The Role of Proteolytic Enzymes in the Treatment of (People With) Cancer

8/3/2019 The Role of Proteolytic Enzymes in the Treatment of (People With) Cancer

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The Role

of

Proteolytic Enzymes

in the Treatment of(people with)

Cancer

© 2010 Bradford S. Weeks, M.D.



Disclaimer –

no commercial interest

or

conflict of interest declared



The Executive Summary

Proteolytic Enzymes:1) selectively attack and kill cancer cells

(nagalese, CIC)2) clean up after themselves

3) prevent metastatic disease

4) offer systemic immune enhancement5) a compelling scientific /clinical pedigree

6) excellent risk/benefit ratio (including cost)



Clinical take Home Message

1) avoid eating junk and enzyme blockers(no such thing as “junk food”)

2) eat enzyme rich food

(raw and sprouted)

3) conserve endogenous enzymes

(eat infrequently and in moderation)

4) use digestive aids(OACV, bitters, anti-pasta, betain HCl and pepsin)

5) supplement with high quality enzymes

(young source and fresh quality)



The Nature of Cancer

1) Inevitable or not?

2) Perpetual or not?

3) Curable or not?4) Infectious or not?

5) What is the role of mind/body?

6) Aggressive or not?



“Nature abhors a vacuum.”

Empty or unfilled spaces are

unnatural as they go against the

laws of nature and physics.



Cancer is not the problem.

Cancer is an adaptive response

to the problem.

Toxic blood and tissue is the

problemEvery town has a garbage dump.

Solution: make less trash, recycle.

To avoid cancer: eat non-toxic foods and eat less!



Whidbey Island mushroom



Removing the tumor is the least

important step in curing someonechallenged by cancer.



Corrective Cancer Care

The

Three-Fold Approach

http://weeksmd.com/?p=3329





First leg: we strive to take down the

“Cancer Welcome” sign by correctingthe environment (both external and

internal) which is “opening the door”

to cancer. This includes correcting andreinforcing the foundation of your

health and vitality:

Nutrition, Exercise and Thought

(the “NET” )



Second leg: we strive to enhance the

immune system through identifying and

correcting imbalances on all four levels of human existence: 1) the material body (using

nutritional and biochemical interventions),

2) the etheric body (using lifestyle and habitmodifications), 3) the emotional body (using

practices for enhancing mastery of mood

“CorThot”) and 4) the spiritual body (using practices for enhancing one’s humanity and

relationship with the Divine).



Third leg: we strive eliminate

cancer cells and tumors using the

best of conventional and

innovative medicine.






Oxygen breathing may be a cheaper and safer alternative to

exogenous erythropoietin (EPO)

Recently discovered “normobaric oxygen paradox” demonstratesthat renal tissue can be stimulated to increase EPO production via a

simple pattern of oxygen breathing at normal atmospheric

pressures. This leads directly to the hypothesis that oxygen

breathing may provide chemotherapy patients with a convenient and

inexpensive alternative to ESAs. Stimulating endogenous EPO

production eliminates the small risk of immune system reaction

associated with ESAs. Further, the endogenous physiological EPO

doses provided by this method may be safer, in terms of cancer

mortality, than the exogenous pharmacological doses inherent inESA administration.

Author: R. Burk Medical Hypothesis published on line 5/ 11/ 07



Change Diet

Change Lifestyle

Change Level of Enjoyment

Change Beliefs and Attitude.

The Challenge:

“People want to be cured with

their sins, not from their sins.”



The role of Hope

“There are no incurable illnesses,

only incurable people”.

Paracelsus



The Role of Diet

Are you feeding yourself ?

or

Are you feeding a cancer?



HOW TO EAT

Not what you eat, but how you eat.

Michio Kushi - father of macrobiotics

1) Say a Grace in order to cultivate

a sense of calm and appreciation

2) chew, chew, chew

3) select good organic foods



Caloric Restriction

Raw and Fermented Foods

Use Digestive Aids

(OACV, betine HCl & pepsin)

Avoid digestive blockers

(antacids, dairy, excess water with meals)

Avoid foods with enyme blockers



Stop the junk!(We can disagree on what is junk,but there is no disagreement

that it is worth avoiding!)



Introduction to Enzymes

metabolicdigestive

food



Availablity of Proteolytic Enzmes

Oral

TopicalTransdermal

Intradermal



ORALDiet

raw and fresh foods

Natto

Supplements:high quality

BoloukeNattokinase

Vit K2



What is this

squirrel doing?



Sprouting (germination) inactivates

endogenous enzyme inhibitors

Enzyme activity in the seed is at

its highest when the sprout is

1/4 inch long.

Soaking and sprouting is EASY



Meat Tenderizing Enzymes

The two most often used meat tenderizing

enzymes are Papain (papaya) and Bromelain

(pineapple).

Ficin, derived from fig tree latex is also used.

Other sources of enzymes are Pancreatin andTrypsin derived from the pancreas gland



Enzymes molecules are protein chains

whose composition and configuration

dictate biological function.

Enzymes are not degraded by activity,co-enzymes are and substrates are.

Catabolic enzymes 97%Anabolic enzymes 3%



Enzymes can produce light –

“cold light” bioluminescence

(firefly, deep sea fish, diatoms)

luciferin catalyzes with oxygen to make an

enzyme complex

“luceferin producellight ”

Gene package LUX inserted into bacteria

which are pathologic to plants to identify

sick plants – glow in the dark;



The Uruguay “railroad worm” has red lamps on head

and rows of green lamps down both sides

Macrophages, bones, GI bacteria - all glow!



Brief History

of

Health Applications

of Proteolytic Enzymes



Zosimos in Greece the original juicer

called the “chymist” Chyme =juice

To avoid prosecution for blasphemy,

he moved to Egypt 3rd century BCwhere his work was referred to as

al kimiya from whence we know the

term alchemy - the study of the

Mysterious Force



Sought the “mysterious

forces” in the

transformation of food

(mechanical crushing

presumed)

Rene-Antoine Ferchant de

Reaumur 1683-1757



Gizzard of the Hawk

experiment:

Meat placed within aperforated

metal capsule

disappeared,

this proved crushing

was not the

mechanism of

digestion.



Lazzaro Spallanzani

(1729-1799)

filled the perforated metalcase with a sponge and

retrieved juice form falcon

gullet which, when applied

in vitro to meat “digestedit”.

Proved digestion was in the

juice.

Proved the force can be

denatured by boiling.



Jean Senebier1742-1809

First modern scientist

(pastor, botanist)

who applied gastric juices to openvaricose ulcers and poorly healing

wounds

also noted for clarifying

“the influence of light on vegetation”



Theodur Schwann 1836

Discovered pepsin -“transmutation of proteins”

Willy Kuhne 1897 Professor of Physiology U. Heidelberg coined the

term “enzyme” defined as

“a biocatalyst that alters protein

outside of a living cell”



Dr. John Beard,

EmbryologistU. Edinburgh

(1857-1924)

Embryonic enzymes

aka “ferments”

See http://users.navi.net/~rsc/beard066.htm



Observation:

“The day the Trophoblast changes behavior was the day

that the embryonic pancreas became active and begins

producing pancreatic proteolytic enzymes.”

Hypothesis:“If pancreatic enzymes can control a trophoblast which is

a very invasive aggressive cancer-like organisism and

convert it into a tame and life sustaining organism, they

should do the same with cancer.”

Beard concluded that cancer was trophoblastic



Beard concluded that cancer was trophoblastic.

Trophoblast is the first differentiated cell to arise after

the zygote is formed by union of sperm and egg. This

cell goes on to form the placenta and is the source cellfor the entire placenta. None of the cells comprising

the placenta are incorporated into the human body, but

neatly surround the entire fetus like a ballon. Somehow

the body destroys this tissue resulting in the birth of theindividual. Beard believed that cancer was this

trophoblast manifesting in the wrong time and place.

Furthermore, he believed that normal trophoblast is

eventually destroyed by the mother and fetus through

their pancreatic secretions, that the totality of these

enzymes constitute the cause of birth.

See http://weeksmd.com/?p=3810



Reasoning:

Young animals need strong enzymes to control

growth.Therefore, doctors can use pancreatic enzymesfrom young animals and use fresh enzymes to “control

cancer growth”.

Declaration:Pancreatic enzymes are the main defense against cancer.

Cancer does not occur in mature cells but in

trophoblastic nests.

The way to cure cancer is to give proteolytic enzymes.”



Treatment:

Fairchild Co. produced injectable enzymes.

Case study 170 patients - cured

Consequence:

Madame Curie PhD discovered radium andproposed as a treatment for cancer -stole the show.

A whole generation of doctors died of leukemia and

lymphoma

Beard’s work was forgotten - in his lifetime.



Early Hackers

(hack jobs)

The refuting studies used stale

enzymes from old animals

Example: fresh pineapple has potent

bromelin but not the canned fruit.



“Dr Beard did not allow himself to

become discouraged, since most of

the patients who came to him were

suffering from terminal cancer hewas prepared to do anything which

offered a ghost of a chance.”

" M di l ki d i i l



"...Medical mankind in particular, were

supposed to be waiting for the advent of

some new scientific discoveryconcerning the nature of cancer... ...The

physical martyrdom was lacking; but

there are, as I can testify fromexperience, many more ways than one of

burning a scientific man at the stake." –

John Beard. D.Sc., The Enzyme Treatment of

Cancer and its Scientific Basis. 1911



Oral

Dr. Max Wolf andDr. Helen Benitez

“WoBe” of wobenzyme

“pancreatin, chymotrypsin,

trypsin, amylase and lipase

Papain bromelain

Rutin a bioflavanoid “Vit P”

Calves thymus hydrolsylates and proteases



Wolf-Benitez enzyme mixture –

inflammation, degeneration andcancer administered to

over

50,000 cancer patients a year

over the past 25 years (1969-1994)

Medical Enzyme Research Institute NY



Topical Enzymes

Heat

Penzim

BVT ointmentHoney

Escarotics (plant/mineral)

Cansema, Bec5 /Curaderm



http://sunwatt.mystarband.net/valueofescharotics1948.htm



I j bl E



Injectable Enzymes

John Bauer Coley Toxin Urokinase

Pancreatic Enzymes

Dr. Neuhofer in Salzburg Austria had MS

Then treated MS patients with

“intramuscular pancreatic enzyme

injections”



William Donald Kelley, DDS

(1925-2005)

He cured himself of pancreatic cancer

He wrote One Answer To Cancer

33,000 cancer cases over 30 years

New Century Promotions 3711 Altal Loma Drive

Bonita, CA 91902 800-768-8484 or 619-479-3829.



Evaluation of Pancreatic Proteolytic Enzyme

Treatment of Adenocarcinoma of the

Pancreas, With Nutrition and DetoxificationSupport

Gonzalez, N. Nutrition and Cancer.

June 1999 issue Vol 33, No 2

Of 11 patients followed in the trial, 8 of 11

suffered stage IV disease. Nine of 11 (81%)lived one year, 5 of 11 lived two years (45%), 4

of 11 lived three years (36%) and two have lived

longer than four years.



In comparison, in a recent trial of the newly approved drug

gemcitabine, of 126 patients with

pancreatic cancer not a single

patient lived longer than 19

months.



Gerson Regimen. Cassileth, B

Oncology. 2010 Feb;24(2):201.

An NCI-sponsored study of Gonzalez therapy,which is similar to the Gerson diet, showed that

patients with inoperable pancreatic

adenocarcinoma who underwent standard chemotherapy with gemcitabine (Gemzar)

survived three times longer and had better

quality of life than those who chose enzymetreatment, which included pancreatic enzymes,

nutritional supplements, detoxification, and an

organic diet.



Dr. Gonzalez’ rebuttal:

“fraud”, “incompetence”,

“conflict of interest”

see

http://www.dr-gonzalez.com/jco_rebuttal.htm

http://www.dr-gonzalez.com/engel_1_05.pdf











“The therapy itself is quite complex, but

basically involves three components: diet,

aggressive supplementation with nutrients

and enzymes, and detoxification. The

protocols are individualized and each

patient receives a diet designed for his or

her specific needs.”

“130 and 175 capsules daily”



“These enzymes are available only to our

patients, and are not available over the

Internet or in health food stores. In ourexperience, quality, manufacturing methods,

and composition vary widely among

commercially available preparations of pancreatic enzymes. The results of our

studies cannot be used as validation for any

other product, whether obtained from ahealth food store, a pharmacy or an Internet

source.” Nick Gonzalez



"In summary, PPE (porcine pancreatic

enzyme) is the first experimentally and

clinically proven agent for the effective

treatment of PC (pancreatic cancer). The

significant advantages of PPE over any

other currently available therapeutic

modalities include its effects on physical

condition, nutrition and lack of toxicity."

Gonzalez, N. Pancreas May 2004



Proteolytic Enzymes

Mechanism of Actions

Molecular & Systemic



Drugs(“drug” derived from “drouge” meaning

“poison” old Eng. 1500’s )

function as enzyme inhibitors.

Bee Venom is an inhibitor of many

enzymes including cyclooxygenase

(“Cox 2 inhibition) like ASA

The proteolytic enzymes include:



The proteolytic enzymes include:

1) Pancreatin (reduces joint discomfort and swelling,

reduces chance of pancreatitis);2) Bromelain (enhances immune system, supports anti-

inflammation, enhances circulation and anti-coagulation,

inhibits excessive blood clotting, reducing joint

swelling);3) Trypsin (accelerates repair of injuries, boosts immune

activity and enhances circulation);

4) Papain (strong anti-inflammatory agent);

chymotrypsin (enhances circulation);

5) Rutin (a free-radical scavanger to serve as anti-

inflammatory)

1) d di h h i CIC



1) degrading the pathogenic CIC

macrophages reactivated (secrete TNF?)

2) attack cancer cells via degradation of fibrin (reveals the cancer antigen)

3) remove adhesive glue

4) more immune complex degradingenzymes and more fibrinolytic enzymes

break down incompletely degraded antigen

immune complexes (relax the complementcascade system)

5) enhance macrophage function



Under the Radar

An Example of Cancer Stealth

Lysis of the normal cells was abolished

when either 75 mM galactosamine,glucosamine or 100 microM

beta-lactoglobulin was added to the

melittin-cell reaction, but lysis of theleukemia cells was unaffected.



The amino-groups appeared

necessary for blockingmelittin-mediated lysis since

glucose, galactose and the N-acetyl

derivatives were not inhibitory.

Bone-marrow cells were more

readily protected from lysis thanspleen cells.



the evidence suggests thatbone-marrow cells are rich in

membrane binding sites for

carbohydrates that decrease in maturespleen cells and are virtually absent

after neoplastic transformation.



Exogenous Proteases Confer a Significant Chemopreventive

Effect in Experimental Tumor Models

Martin Wald, MD

Integrative Cancer Therapies, Vol. 7, No. 4, 295-310 (2008)

The chemopreventive effects of enterally administered proteases

(trypsin, chymotrypsin, and papain) have been documented in a

series of animal experimental tumor models. The experimentalevidence demonstrates a significant inhibition of growth of both the

primary tumor and the metastatic disseminations. Survival in animals

treated with proteases is significantly longer than in untreated

animals.Comparable results have been shown in solid tumors inanimal models (melanoma and Lewis lung carcinoma) and in human

tumors (pancreatic and breast cancers).

REFERENCE BOOKS



REFERENCE BOOKS

John Beard The enzyme Treatment of Cancerand its Biological Basis pub 1911

Max Wolf and his Enzymes

Enzymes the Fountain of Life byLopez,

Williams and Miehlke Neville Press 1994

Dr. Edward Howell’s Enzyme Nutrition 1985



OTHER MECHANISMS OF ACTION

Enhance TNF

(interferon, Japanese fungus extract)

Mimics: Plasmapheresis and lymphapheresis

Mimics: cryoprecipitation

(protein A adhesion) removes CIC

Fever -

at 104 deg, enzymes are in a fever of activity -higher -> denature, lower -> sluggish;

“If you want life, eat living things.” Raw liver



Venoms

as

Medicines



“Poisonis a matter of

dosage”.

T.B.vH. Paracelsus



Scorpion Venom Tested Against Brain Cancer

Memelak et al. J of Clinical Oncology Aug 2006







Snake Venom May Slow Cancer

Growth, Studies Hint

"Snakes use venom to alter biological

functions, and that's what medicinedoes too. This is why venoms have

always been of interest to medicalresearchers."

John Perez, Natural Toxins Research Center, Texas A&M University-Kingsville

Therapeutic Benefits of BVT



1) Arthritis:

RA,OA, JRA, frozen shoulder, tennis elbow,sciatica, back pain;

2) Neurological Illnesses:

Multiple Sclerosis, Parkinson’s, ALS 3) Cancers:

Breast, Prostate, Colon, Melanoma, L&L

4) Infective diseases:Viral – mono, warts, AIDs, herpes, cancer

Spirochete – Lyme’s disease

5) Analgesia and sclerolysis











Anti-Inflammation



Inhibitory effect of whole bee

venom in adjuvant-inducedarthritis.

In Vivo 2005 Jul-Aug;19(4):801-5. Lee JY, Republic of Korea.

“The aim of this study was to assess theinhibitory effect of whole bee venom (BV) on

adjuvant-induced arthritis in the rat.”

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=PubMed&cmd=Search&itool=PubMed_Abstract&term=%22Lee+JY%22%5BAuthor%5D





“In conclusion, whole BV was foundto inhibit arthritic inflammation and

bone changes in the rat.

This may be an alternative treatment

for arthritis in humans.”



Oncological Applications

of

Honey Bee Venom



Bee venom protects against x-radiation

Melittin used as a protective agentagainst x-irradiation.

Ginsberg, Dauer, Slotta Nature. 1968 Dec 28. 220(174). P 1334.

Melittin stimulates Na entry Na-K



Melittin stimulates Na entry, Na K

pump activity and DNA synthesis in

quiescent cultures of mouse cells.Rozengurt, Gelehrter et al

Cell 1981 Mar. 23(3). P 781-8.

Melittin, an amphipatic polypeptide,increases several fold the activity of Na-K

pump in quiescent Swiss 3T3 cells.

As with other growth factors, melittin

increases the activity of the pump by

increasing Na entry into the cell.

In contrast, other early responses are not



In contrast, other early responses are not

elicited by the toxin. At concentrations that

promote ion fluxes, melittin stimulatesDNA synthesis in quiescent mouse cells

acting synergistically with insulin,

epidermal growth factor and with thegrowth factor released by SV40 BHK

cells.The cellular effects of melittin are

consistent with the proposal that ion fluxessignal the initiation of mitogenesis in

quiescent cells.

Inhibition of growth of leukemic cells by



inhibitors of calmodulin: phenothiazines

and melittin. Hait, Grais et al Cancer-Chemother-Pharmacol. 1985. 14(3). P 202-5.

Calmodulin, a ubiquitous calcium-binding

protein, has recently been shown to play an

important role in cellular proliferation. The

calmodulin inhibitors melittin, trifluoperazine,

and chlorpromazine inhibited the growth and

clonogenicity of human and murine leukemiccells, and their potency reflected their activity as

inhibitors of calmodulin.

M li i hi h i f



Melittin, which is a far more potent

inhibitor of calmodulin activity,was also a more potent inhibitor of

cell growth and clonogenicity. The

less active phenothiazine

metabolite, chlorpromazine

sulfoxide, had much less potentcytotoxic activity.



Cancer cells cover their antigens under a adhesive fibrin

layer which is 15 times thicker than that of normal cells

thereby escaping detection while they proliferate. (253)

Blocking factors

Proteolytic enzymes sweep up residual antigen particlesotherwise platelet aggregation and activation are caused

by the undegraded immune complexes which remain in

circulation and lymph system.

CIC increases complement cascade – further damaging

tissues



Melittin-stimulated antimycobacterial

activity of the membrane fraction isolated

from phagocytes of guinea pigs.Kondo-E. Jpn-J-Med-Sci-Biol. 1986 Feb. 39(1). P 21-4.

Virulent tubercle bacilli - A markedinhibition of mycobacterial growth was

observed in the presence of added melittin

which is known as an activator of membrane phospholipase A.



Bee venom induces apoptosis through

caspase-3 activation in synovial

fibroblasts of patients with rheumatoidarthritis.

Toxicon 2005 Jul;46(1):39-45.

Hong SJ, Rim GS South Korea.

The anti-inflammatory effect of



peripheral bee venom stimulation is

mediated by central muscarinic type 2receptors and activation of sympathetic

preganglionic neurons.

Brain Res. 2005 Jul 12;1049(2):210-6.

Yoon SY South Korea.

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=PubMed&cmd=Search&itool=PubMed_Abstract&term=%22Yoon+SY%22%5BAuthor%5D



Cytotoxic properties of

immunoconjugates containingmelittin-like peptide 101 against

prostate cancer: in vitro and invivo studies.

Russell PJ, Hewish D, Carter T et al.



The induced apoptosis of

recombinant adenoviruscarrying melittin gene for

hepatocellular carcinomacell.

[Article in Chinese]

Li B, Ling CQ, Zhang C Li SX



.

Inhibitory effect of

recombinant adenoviruscarrying melittin gene on

hepatocellular carcinoma.

Ling CQ, Li B, Zhang C

Ann Oncol. 2005 Jan;16(1):109-15



Differential cytolysis of murine spleen,

bone-marrow and leukemia cells by melittin

reveals differences in membrane topography.Killion-J-J. Dunn-J-D.

Biochem-Biophys-Res-Commun. 1986 Aug 29. 139(1).

P 222-7.L1210 leukemia cells are 2-4 fold more sensitive

to the cytolytic effects of melittin, the

membrane-active toxin of bee venom, thannormal DBA/2 mouse spleen and bone-marrow

cells.



[Effect of melittin on

apoptosis and necrosis ofOsteosarcoma cells]Chen YQ, Zhu ZA, Zhang C

“CONCLUSION: Melittin inhibits the

proliferation of osterosarcoma cell linethrough up-regulating Fas expression

and inducing apoptsis.”



Bee venom induces apoptosis and

inhibits expression of cyclooxygenase-2mRNA in human lung cancer cell line

NCI-H1299.

J Pharmacol Sci. 2003 Feb;91(2):95-104. Jang

MH,



“Expression of COX-2 mRNA and

synthesis of PGE(2) were inhibitedby Bee Venom.

These results suggest the possibility

that Bee Venom may exert an

anti-tumor effect on human lungcancer.”



“Dear Dr. Weeks,

In our studies we successfully destroyed

prostate and breast cancer tumors and

metastases with membrane disruptingpeptides; examples for these are

naturally occurring peptides like

mellitin.



These peptides destroy the outer cell

membrane and cause rapid cell

death in vitro and in vivo.

Carola Leuschner, PhD”



“Hyaluronan promotes

tumorigenesis, the level of HA onthe surface of cancer cells correlating

with aggressiveness and pooroutcome.”

(Zhang et al., 1995)..



Effect of honey bee venom on

proliferation of K1735M2 mousemelanoma cells in-vitro and growth of

murine B16 melanomas in-vivo.

J Pharm Pharmacol. 2002

Aug;54(8):1083-9.

Liu X, China.

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Liu+X%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Liu+X%22%5BAuthor%5D



“Bee venom has been reported to

exhibit antitumour activity in-vitro andin-vivo.”

“Apoptosis, necrosis and lysis of tumour

cells were suggested as possible

mechanisms by which bee venominhibited tumour growth.”



“The in-vivo experimentindicated that bee venom

could be used as achemotherapeutic agent

against malignant tumors.”



A matrix metalloproteinase 2

cleavable melittin/avidin conjugate

specifically targets tumor cells in vitro

and in vivo.

Int J Oncol. 2003 Jan;22(1):93-8.

Holle L, Song W,

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Holle+L%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Song+W%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Song+W%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Holle+L%22%5BAuthor%5D



“Melittin alone is extremely toxic to

cells and induces immediate celllysis, but becomes inactive when

coupled with avidin.

The incorporation of the MMP2

target sequence into the peptide was

used as a means for targeting tumorcells.”

Bee venom induces apoptosis and



inhibits expression of cyclooxygenase-2

mRNA in human lung cancer cell lineNCI-H1299.

J Pharmacol Sci. 2003 Feb;91(2):95-104.

Jang MH, Shin MC, Seoul, Korea.

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Jang+MH%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Shin+MC%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Shin+MC%22%5BAuthor%5D

http://www.ncbi.nlm.nih.gov.offcampus.lib.washington.edu/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_Abstract&term=%22Jang+MH%22%5BAuthor%5D



Immune Stimulant Effect

Inject at Command Points

BVT suppresses suppressor T-Cells

Acute pain is immuno-stimulatingChronic pain is immuno-suppressive



Dr. Rudolf Steiner

father of Anthroposophy

“Nine lectures on Bees”

Dornach, Switz. 1923



“Poisons are gatherers of

what is spiritual; for thisreason they are healing

remedies.”

Dr. Rudolf Steiner



“The remarkable thing is this; that substances

that can make a man ill or even kill him, canalso cure him. This is one of the great

responsibilities one has in the preparation of

medicines, for there are no real remedieswhich, if wrongly applied, cannot cause the

same illnesses which they can also cure.”

Dr. Rudolf Steiner



“I told you that these creatures all

have a poisonous substance withinthem and that this poisonous

substance, if given in the right dose,

is an excellent remedy. Bee venom is

an excellent remedy”.

Dr. Rudolf Steiner

“The ego-organization works directly



in the circulation of the blood. Now

it is actually the case that his ego-

organization is in a mysterious way

present in the poison of the bee; it isa similar force to the force that

circulates in your blood that ispresent in the bee venom”.

Dr. Rudolf Steiner



Topical Applications

Proteolytic Enzymes



Irritant

/Counter-Irritant

Therapy



“Give me the power to createfever

and I will cure all illness”. Parmenides (500 BC)



Metastatic ovarian cancer

pre BVT and pre Penzim













The role of the teacher

“One cannot cure a chronic illness. The

best one can hope for is to return it to

its acute phase; only then do you onceagain have the opportunity to cure it.”

Hahnemann





Honey

May PreventRecurring Tumors

Dr. Ismail Hamzaoglu

Istanbul University

Dec 2004, Archives of Surgery.



A Mayo Clinic cancer expert said the

results, though preliminary, are

“too fascinating to be dismissed.”



Topical Honey Application vs.

Acyclovir for the Treatment ofRecurrent Herpes Simplex

Lesions.

Med Sci Monit, 2004; 10 (8)

Al Waili, N.S. Dubai UAE



“Two cases of labial herpesand one case of genital herpes

remitted completelywith

the use of honey.”

Results:



For labial herpes, the mean duration of attacks

and pain, occurrence of crusting, and mean

healing time with honey treatment were 35%,

39%, 28% and 43% better, respectively, than with

acyclovir treatment.

For genital herpes, the mean duration of attacks

and pain, occurrence of crusting, and mean

healing time with honey treatment were 53%,

50%, 49% and 59% better, respectively than with

acyclovir treatment.

CONCLUSION:



“Topical honey application is

safe and effective

in the management of the signs and

symptoms of recurrent lesions fromlabial and genital herpes.”



Comparative Costs

Acyclovir $3,810.00 / pound

Raw Honey $15.00 / pound



THE LEG





























THE CHEEK





















“This is the word of the Lord. Give

your last instructions to your



your last instructions to your

household, for you are a dyingman and will not recover.”

2nd Book of Kings, Chapter 20

M.D. = Medical Deity ?

Hezekiah was dying.



“Then Isiah told them to apply a

fig plaster. So they made one and

applied it to the boil and herecovered.”

….And lived another 15 years.

Proteolytic enzymes in fig

“the fresh figs were boiled then



g

opened up and placed on the patientsface with the skin being eaten away on

half his face, they were bandaged up

onto his face and left there for 4weeks, when removed the cancer had

completely gone.”

Culpepper’s Old English Herbal

The fig plant produces

a latex that contains



ficin, a protein-

decomposing enzyme

similar to papain.

Contact with skincauses dermatitis,

making use of gloves

advisable whenworking with or

harvesting figs.

Summary:

P t l ti E Th



Proteolytic Enzyme Therapy

potent agents

help overcome cancer

excellent risk / benefit ratioavailable: oral, injectable, topical

benefits: local and systemic effects

strong scientific and clinical support

Summary:

P l i E Th



Proteolytic Enzyme Therapy

(continued)

Caveats:

products must be fresh

proteolytic therapies are

adjunctive to the lifestyle“The NET”

Nutrition Exercise and Thought



Take Home Benefits

of

Proteolytic Enzymes







Thank you



and….

Bee Well!

Bradford S. Weeks, M.D.



The Weeks Clinic

for

Corrective

Medicine and Psychiatry

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The Role of Proteolytic Enzymes in the Treatment of (People With) Cancer

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