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BONE FUNCTION: Support and Protection
Give shape and provide protection to head, face, thorax, and limbs
Structural support for heart, lungs and marrow
Protection for brain, uterus, and other internal organs
Attachment sites for muscles allowing movement of limbs
BONE FUNCTION:Body Movement
Movement is possible through of the attachment of bones to muscles. (Tendons)
Bones and muscles interact as mechanical devices called levers.
4 basic components of levers: 1) rod or bar 2) pivot point 3) object moving against resistance
4) force supplying energy McGrallHill Textbook
BONE FUNCTION:Blood Cell Formation
3 groups of blood cells: red blood cells, white blood cells, and platelets
Also called hematopoiesis Begins in the yolk sac, later occurs in the
liver and spleen, and finally in bone marrow Marrow: soft mass of connective tissue
found within medullary cavities of long bones, spongy bone, and central canals of compact bone tissue
2 kinds of bone marrow: Red marrow and yellow marrow
Continued…
Red marrow: formation of red blood cells, white blood cells and platelets.
In infants, red marrow occupies the cavities of bones
Yellow marrow: stores fat. Is not active in blood formation
However, if needed, can become red marrow, then reverts back to yellow marrow
www.propofs.com
BONE FUNCTION:Storage of Inorganic Salts
• The extracellular matrix of bone tissue is rich in calcium salts
• Vital Metabolic processes require calcium• When blood is low in calcium, osteoclasts
break down bone tissue, which releases calcium salts into the blood
• High blood calcium activates osteoclasts and causes the release of calcitonin, which stimulates osteoblasts to form bone tissue.
• Excess calcium is stored in the extracellular matrix
Bones
• Bone tissue is a type of dense connective tissue.
• Come in a variety of shapes and have a complex internal and external structure
• Lightweight, yet strong and hard• Rigid and has a honeycomb-like, three-
dimensional internal structure. • Includes marrow, endosteum and periosteum,
nerves, and blood vessels • There are 206 bones in the adult human body
and 270 in an infant.
Ligaments
• Connect bone to another bone
• Allow most joints to move help control their range of motion
• Stabilize them so that the bones move in proper alignment
• Collagen makes up the tissue in most ligaments.
• Collagen fibers allow to stretch significantly when they move, such as when the elbow is bent or straightened.
http://www.wisegeek.com/what-are-ligaments.htm
Tendons
• Tough band of fibrous connective tissue that usually connect muscle to bone
• Capable of withstanding great tension.
• Similar to ligaments and fasciae as they are all made of collagen but ligaments join one bone to another bone, and fasciae connect muscles to other muscles.
• Tendons and muscles work together
http://www.wisegeek.org/what-are-tendons.htm#slideshow
Cartilage
• Flexible connective tissue found in many areas in the body like the rib cage, the ear, the nose.
• Provide support, frameworks, and attachments
• Protect underlying tissues• Form structural models for
developing bones• Not as hard and rigid as
bone but is stiffer and less flexible than muscle.
• 3 types: elastic cartilage, hyaline cartilage and fibrocartilage
• Do not contain blood vessels and as a result, heals very slowly.
http://www.tumblr.com/tagged/elastic%20cartilage
http://tissueslides.blogspot.com/2009/10/fibrocartilage.html
http://washington.uwc.edu/about/wayne.schaefer/TissuesPage.htm
Bone Development and Growth
The skeletal systems begins to grow during prenatal development
Continues to grow into adulthood Form by replacing existing connective
tissues 2 types of bone formation:
Intramembranous and endochondral
Bone Development and Growth:Intramembranous Ossification
Formation of flat bones like the skull Connective tissue forms in sheets at sites of
future bones Highly invested with blood vessels. The future bones are first formed as connective
tissue membranes. Osteoblasts migrate to the membranes and
deposit bony matrix around themselves. As a result, spongy bone tissue forms in all
directions within the membrane layers Periosteum: cells of the membranous tissues that
lie outside the developing bone Osteoblasts lie within the periosteum and form
compact bone around spongy bone
Endochondral Ossification:
Future bones first form as hyaline cartilage models.
3rd month after conception: the perichondrium that surrounds the hyaline cartilage models fills with blood vessels and osteoblasts and changes into a periosteum.
The osteoblasts form a collar of compact bone around the diaphysis. Cartilage in the center of the diaphysis begins to disintegrate.
Osteoblasts penetrate the disintegrating cartilage and replace it with spongy bone.
• Continues from the center toward the ends of the bones.
• After spongy bone is formed in the diaphysis, osteoclasts break down the newly formed bone to open up the medullary cavity.
• As the developing bone increases in length, cartilage continues to disintegrate
• When secondary ossification is complete, the hyaline cartilage is totally replaced by bone but a region of hyaline cartilage remains over the surface of the epiphysis as articular cartilage
Primary Ossification Center
Secondary Ossification Center
• Replacement of hyaline cartilage with bony tissue.
• Most of the bones of the skeleton are formed in this manner.
Axial v. Appendicular Skeletons
Axial: Head, neck and trunk
Appendicular: Upper and lower limbs
http://bodyorgans.blogspot.com/2012_09_01_archive.html
Major Bones of the Body: Anterior View
Femur
Humerus
Fibula
Tibia
RadiusUlna
Skull
Sternum
Ribs
Carpals
Phalanges
Coxa
Metacarpals
Tarsals
MetatarsalsPhalanges
Clavicle
Patella
http://kootation.com/this-actually-made-me-cry-such-humanity.html
Major Bones of the Body:Posterior View
Scapula
Sacrum
Coccyx
Floating RibsVertebral Column
http://www.clker.com/clipart-skeleton-posterior.html
Joints of Different Tissue
http://www.infovisual.info/03/img_en/026%20Types%20of%20joints%20found%20in%20the%20human%20body.jpg
Joints
Fibrous Lie closely between one another Thin layer of dense conn. tissue I.e. sutures on skull bones
Cartilaginous Hyaline cartilage or fibrocartilage Separate the vertebral column
Synovial Mostly of all joins Allows free movement Complex structures
Six Synovial Joints
HINGE
Condyloid
Gliding
PIVOT
BALL-AND-SOCKET
SADDLE
http://classconnection.s3.amazonaws.com/404/flashcards/1237404/jpg/slide321333990034923.jpg
http://www.usi.edu/science/biology/mkhopper/hopper/BIOL2401/LABUNIT2/01Ex12Joints/Ex.13Images/DorsiPlantar.jpg
http://d3j7fudf8o8iuo.cloudfront.net/var/ezwebin_site/storage/images/media/images/e-anatomy/anatomical-terms-of-location-position-motion/inversion-eversion/2511097-1-eng-GB/inversion-eversion_imagelarge.jpg
http://www.baileybio.com/plogger/images/anatomy___physiology/04._powerpoint_-_skeletal_system/protraction___retraction.jpg
http://www.usi.edu/science/biology/mkhopper/hopper/BIOL2401/LABUNIT2/01Ex12Joints/Ex.13Images/DorsiPlantar.jpg
http://www.baileybio.com/plogger/images/anatomy___physiology/04._powerpoint_-_skeletal_system/elevation___depression.jpg
Osteoporosis
http://1.bp.blogspot.com/-QAa7G65np08/Tcq0QVHnkrI/AAAAAAAAAWs/dZcSfC0WQYo/s1600/osteoporosis1.jpg
• Thinning and weakening of the bone
• More common to women
• Low bone density and low dietary sodium intake
• Hips, wrists, and spine
• Considered a ‘silent disease’
• Can be prevented or treated with a healthy lifestyle; correct diet, exercise, and medications such as bisphonates
OSTEOPOROSIS=POROUS BONE
Osteogenesis Imperfecta
Congenital Disease More common within
shorter stature Bones become weaker Damages in the gene for
type 1 collagen Blue tint to the whites of
the eye, hearing losses, and multiple fractures
No definite cure http://www.primehealthchannel.com/wp-content/uploads/2011/08/Osteogenesis-Imperfecta.jpg
Bone Tumor
Abnormal growth of bones
Genetics, radiation, injury
Symptoms: Pain (night) and fractures
Treated like most cancers
http://www.magmire.net/wp-content/uploads/Dog-Bone-Tumors.jpg
"Bone tumor - PubMed Health." National Center for Biotechnology Information. N.p., n.d. Web. 26 Feb. 2013.
<http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002210/>
"Osteogenesis imperfecta - PubMed Health." National Center for Biotechnology Information.
Web. 23 Feb. 2013. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002540>
"NIHSeniorHealth: Osteoporosis - What Is Osteoporosis?." NIHSeniorHealth Home Page. N.p., n.d. Web. 24 Feb. 2013.
<http://nihseniorhealth.gov/osteoporosis/whatisosteoporosis/01.html>
Shier, David, Jackie Butler, and Ricki Lewis. Hole's essentials of human anatomy and physiology. 9th ed. Boston: McGraw-Hill,
2006. Print.
Work Cited