The Top 20 Drugs Your Dental Patient is Taking:

Drug Interactions and Oral Manifestations

Ronald S. Brown, DDS, MS

The Top Twenty Prescriptions

Rxlist.com/top200.htm2002 drugsNew & Refill

#1, #1 - #4 Hydroxycodone/APAP #3

Oral narcotic analgesic abuse potential

#2, #2 - #8 Lipitor #62

atorvastatin cholesterol lowering agent

#3 Atenalol, #4, #5

Previous brand name Tenormin Beta blocker – selective B1 Negative on lipid profile

#4, #5, #4 - #2 Synthroid #3

Levothyroxine Na Thyroxin replacement drug

#5, #3, #3 - #2 Premarin #1

Conjugated estrogen hormone replacement breast and ovarian cancer vs.

osteoporosis

#6, #7, #19 - #7 Zithromax #9

Azithromycin antibiotic new generation erythromycin less drug interactions

#7, #8 Furosemide

Furosemide Diuretic (very potent) Dry mouth

#8, #9, #14 - #15 Amoxicillin #33

Broad spectrum antibiotic Good penetration Gram positive organisms

#9, #10, #9 - #9 Norvasc #10

Amlodipine besylate Long-acting calcium channel

blocking agent drug-induced gingival

overgrowth/hyperplasia

#10, #14, #17 Hydrochlorothiazide

HCTZ Diuretic Decreases lipid profile K+ loss Dry mouth

#11, #11, #10 Alprazolam

Alprazolam/Xanax (one of the brand names)

Sedative-hypnotic Benzodiazepine class of drugs Anti-anxiety

#12, #12, #8 - #13 Albuterol Aerosol #18

Albuterol (Ventolin) B2 receptor agonist Asthma medication

#13, #16, #18 - #12 Zoloft #11

Sertraline 5HT re-uptake inhibitor Dry mouth

#14, #17 Paxil

Paroxetine 5HT reuptake inhibitor Antidepressant Dry mouth

#15, Zocor

Simvastatin Cholesterol lowering

#16, Prevacid

Lansoprazole H1 blocker GERD

#17, #20, #21 Ibuprofen

NSAID Analgesic, antipyretic GI problems, ulcers Increased bleeding Drug interactions Asthma

#18, #18 Triamterene/HCTZ

Diuretic Combination HCTZ and K+ sparing Dry mouth

#19, #13 - #20 Cephlexin #27

Cephlosporin Staph activity Cross-reacts - allergy with

penicillin – 5 -15%

#20 Celebrex

Celecoxib Selective Nsaid\Cox II inhibitor Analgesia