The Ultimate Protectionfor every generation

Clinpro™ White Varnish5% Sodium Fluoride White Varnish

Clinpro™ Tooth Crème0.21% w/w Sodium Fluoride Anti-Cavity Paste

EXCLUSIVE TRI-CALCIUM PHOSPHATE FORMULA

Preventive Care Solutions

Clinpro™ White Varnish5% Sodium Fluoride Varnish with Tri-Calcium Phosphate

Clinpro™ White Varnish 5% Sodium Fluoride provides a prolonged, steady fluoride delivery—enhancing absorption into the tooth, giving the protection you expect for patients of all ages.

Advantages

Protection you can’t see

Steady fluoride release

Easy to apply

Flows better

Before your patients leave the chair,

apply that extra layer of preventive care

Apply Clinpro™ White Varnish evenly in a thin layer over treatment area(s) with sweeping, horizontal

brush strokes. No suction required.

Clinical studies show that Clinpro™ White Varnish flows to more than twice as many tooth surfaces after application.

Unlike varnishes that release most of their fluoride in the first hour, Clinpro™ White Varnish provides a prolonged, steady

delivery of fluoride, allowing absorption into the tooth.

Clinpro™ White Varnish and the competitive varnishes were applied to 8 anterior maxillary surfaces in vivo. Migration of

the varnishes was measured at 1 hour and 4 hours. Source: 3M ESPE Dental Data on file

Clinpro™ White Varnish delivers a steady release of fluoride throughout the wear time.

Source: 3M ESPE Dental Data on file

Clinpro™ White Varnish is virtually invisible on the teeth—but leaves a temporary thin coating so patients

know it’s working.

Migration of Varnish

15

10

5

0

20

25(Mean +/– SEM; n=19)

Migration of Varnish

Initial 1 hour 4 hours

Clinpro ™ White VarnishCompetitive Varnish

Competitive Varnish

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Clinpro™ White Varnish with TCP

40

50

60

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80

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Cumulative Fluoride Release(± 95% confidence interval; 3 lots, n=5 each)

“Most studies showing a higher efficacy of fluoride varnish attribute it to its increased contact time.”*

• Optimised formula with Tri-Calcium Phosphate (TCP) delivers targeted and sustained release of fluoride and calcium.

• Adheres to the teeth for continuous fluoride contact.

• Migrates to areas that are hard to reach, including interproximal spaces.

• Easy to apply to moist teeth - application takes just seconds.

• Provides relief from hypersensitivity (22,600ppm Sodium Fluoride)

• Available in Mint flavour & sweetened with xylitol.

• The patient can eat and drink following the application.

Clinpro™ Tooth Créme 0.21% w/w Sodium Fluoride Anti-Cavity Paste with Tri-Calcium Phosphate

Advantages

Clinpro™ Tooth Crème is an advanced formula containing an innovative Tri-Calcium Phosphate ingredient available exclusively from 3M ESPE.

This winning formula is a one-step process requiring patients to simply brush with it twice daily in place of their conventional tooth paste (eliminating the two step regimen associated with topically applied products). Clinpro™ Tooth Crème’s innovative f TCP formula maximises the performance of both calcium and fluoride to provide improved fluoride delivery, resulting in strengthening of enamel and reversal of white spot lesions.

Fluoride Uptake1 [Mean +/- SEM]

Topical Creme with Calcium Phosphate

(900 ppm F-)

Clinpro™ Tooth Crème 0.21% w/w Sodium

Fluoride Paste

Topical Creme with Calcium Phosphate

(900 ppm F-)

Clinpro™ Tooth Crème 0.21% w/w Sodium

Fluoride Paste

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Fluoride Uptake1 [Mean +/- SEM]

Topical Creme with Calcium Phosphate

(900 ppm F-)

Clinpro™ Tooth Crème 0.21% w/w Sodium

Fluoride Paste

Topical Creme with Calcium Phosphate

(900 ppm F-)

Clinpro™ Tooth Crème 0.21% w/w Sodium

Fluoride Paste

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Clinpro™ Tooth Crème 0.21% w/w Sodium Fluoride Anti-Cavity Paste delivers more fluoride to the tooth.

Clinpro™ Tooth Créme remineralises throughout the body of early lesions, resulting in smaller and less severe lesions after treatment.

Clinpro™ Tooth Crème 0.21% w/w Sodium Fluoride Anti-Cavity Paste

strengthens teeth.

• Prevents dental caries and reduces root cavities.

• Contains 0.21% w/w Sodium Fluoride (950 ppm fluoride ion).

• Contains an exclusive and innovative calcium and phosphate ingredient.

• Gentle and effective cleaning.

• Cleans and whitens teeth.

• Low abrasion.

• Available in a convenient 113g flip-top tube.

• Simple one step regimen that ensures higher patient compliance.

Strengthens teeth Helps repair early lesions.Delivers more fluoride to the tooth

0

Reduces Lesion Size*

Placebo

After 10 days of pH cycling—cross-sectional microhardness lesion severity [vol % mineral X µm ± SEM]

Cross-sectional microhardness assessment of enamel remineralisation from calcium-containing NaF formulations. Caries Research 43 (Abstr 118), 221 (2009). Additional data.

Clinically proven 1100 ppm F benchmark

900 ppm F + CPP-ACP

Clinpro™ Tooth Crème 0.21% w/w Sodium Fluoride Paste

1000 2000 3000 4000 5000 7000

After 10 days of pH cycling—cross-sectional microhardness lesion severity [vol % mineral X μm ± SEM]

Cross-sectional microhardness assessment of enamel remineralisation from calcium-containing NaF formulations.

Caries Research 43 (Abstr 118), 221 (2009).

So much protection

So simple to use

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3M and Clinpro are trademarks of 3M. Please recycle. Printed in Australia. © 3M 2015. All rights reserved. PB7321/0415

Tri-Calcium Phosphate (TCP) is an innovative calcium-based additive exclusively from 3M ESPE that allows calcium, phosphate and fluoride to co-exist in an aqueous solution. In very simple terms, TCP is specially milled so an organic calcium phosphate hybrid is formed. (Fig. 1).

How Tri-Calcium Phosphate (TCP) really works? “Smart Tri-calcium phosphate” releases calcium and phosphate on the teeth, not in the formulation.

Ordering Information

Fig. 1: Organic components (often surfactants) have an affinity for tooth surfaces—and carry calcium to the tooth surface, protected from fluoride ions. Saliva activates the protected calcium compound by degrading the protective coating and releasing the calcium making it available to the tooth surface, along with the fluoride, ensuring mineral deposition.

What happens when Clinpro™ Tooth Creme reaches the tooth surface through brushing?

Calcium Oxides

Contact with Saliva

3M ESPE Dental

3M Australia Pty LimitedBuilding A, 1 Rivett RdNorth Ryde NSW 2113Ph: 1300 363 878www.3m.com.au/espe

3M New Zealand Limited94 Apollo DriveRosedale Auckland 0632Ph: 0800 80 81 82www.3m.co.nz/espe

Item Product Information

12250 Clinpro™ White Varnish with Tri-Calcium Phosphate 100 Value Pack - Mint Flavour

1 Box of 100 Unit-Dose Pouches (0.50mL) - Mint 1 Box of 100 applicator brushes 2 Pads of 50 Patient IFUs 9 sheets of 12 stickers 1 Technique Card

12216 Clinpro™ Tooth Crème 0.21% Sodium Fluoride Anti-Cavity Paste with Tri-Calcium Phosphate

113g tube, Vanilla Mint flavour

Contact your local 3M ESPE sales representative to learn more about our full line of preventive products