THINK INNOVATION

Jaap Trappenburg

eHealth innovation in the Netherlands, the Utrecht region and THINC.

Hi Emma, I am your assistant doctor

https://www.google.nl/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=2ahUKEwjgmpLOtvndAhUGfFAKHZEiA5sQjRx6BAgBEAU&url=https://store.google.com/gb/product/google_home&psig=AOvVaw0YukXPUr5Mq-xoH58KgEvd&ust=1539176817629544

Outline

• eHealth – some framing • eHealth innovation in the Netherlands • regional innovation ecoystem eHealth

Utrecht • THINC. - The Healthcare Innovation Center • My own research – example projects

ehealth

ehealth

ehealth

http://www.google.nl/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=2ahUKEwj-z_Tz_PbdAhUH3aQKHYysCPMQjRx6BAgBEAU&url=http://colmi.manufacturer.globalsources.com/si/6008846317686/pdtl/Activity-tracker/1161695077/Smart-Wearables-Health-Smartwatch.htm&psig=AOvVaw2q_n6fMt0Ff9tDRrppP6Bg&ust=1539092554361430 http://filmi-onlain.info/jpgspng-slim-textiel.shtml https://www.google.nl/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=2ahUKEwjgmpLOtvndAhUGfFAKHZEiA5sQjRx6BAgBEAU&url=https://store.google.com/gb/product/google_home&psig=AOvVaw0YukXPUr5Mq-xoH58KgEvd&ust=1539176817629544 https://www.google.nl/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&cad=rja&uact=8&ved=2ahUKEwi9w4L9nffdAhVE66QKHV2WD2oQjRx6BAgBEAU&url=https://www.onlinewebfonts.com/icon/535483&psig=AOvVaw06dZfFuCv8khqVs-lUbRwW&ust=1539101481062987

Different (& less strict) regulatory evaluation process • To market after CE approval (if required) • The focus is on ‘safety and techical feasibility’ i.s.o. clinical effectiveness • Different market – shorter life cycle • Lower budgets – less time

Increasingly data driven + autonomous Emerging technologies: AI, precision medicine, genomics, blockchain etc.

Increasingly disruptive Digital transformation, substitution, citizen-centric,

Democratized, digital innovation is increasingly a non- academic activity Global market: 2017 - USD 47.60 billion, 2023 - USD 132.35 billion

They come with many + highly diverse i.e. > 335.000 mobile health apps

Outline

• eHealth – some framing • eHealth innovation in the Netherlands • regional innovation ecoystem eHealth

Utrecht • The Healthcare Innovation Center • My own research – example projects

Drivers eHealth innovation in NL

• Because we need it • Policy (top down) • Knowledge economy / innovation

(bottom up)

Because we need it

Healthcare expenditure Annual increase of 2.9%

By 2040  174 billion Euro (9.6 K / person)

By 2022, a shortage of 100 to 125 thousand healthcare employees is

expected

Active policy • Set SMART goals

– >80% of chronically ill access to their medical records – 75% of chronically ill able to monitor certain aspects of their own health and share the data with their health

provider – People receiving care at home should be able to communicate with their care provider 24 hours a day via a

screen, if they wish.

• Measure longitudinal trends in eHealth uptake / barriers / facilitators (annual eHealth monitor)

• Sharing knowhow (i.e. annual eHealth week) • Improve digital integration and harmonized national data standards (i.e. Legal

framework for mandatory exchange of data, legal certification for a digital ledger solution  blockchain) • Stimulate innovation (i.e. Research Grants, public private partnership matching,

ZorgInnovatie.nl : community for innovation in healthcare and wellbeing, providing a platform and database for more than 3300 communities and 700 innovations.

Set SMART goals • >80% of chronically ill access to their medical records • 75% of chronically ill able to monitor certain aspects of

their own health and share the data with their health provider

• People receiving care at home should be able to communicate with their care provider 24 hours a day via a screen, if they wish

Measure longitudinal trends in eHealth uptake, barriers and facilitators annual eHealth monitor

Improve digital integration and harmonized national data standards i.e. Legal framework for mandatory exchange of data, legal certification for a digital ledger solution incl. blockchain

Stimulate innovation i.e. Research Grants, public private partnership matching, ZorgInnovatie.nl : community for innovation in healthcare and wellbeing, providing a platform and database for more than 3300 communities and 700 innovations.

Sharing knowhow i.e. annual eHealth week

Government policy

https://www.google.nl/url?sa=i&rct=j&q=&esrc=s&source=images&cd=&ved=2ahUKEwjyz8jEzbviAhUNGewKHcEWDxIQjRx6BAgBEAU&url=https://www.volkskrant.nl/nieuws-achtergrond/tweede-kamer-krijgt-er-een-hoofdpijndossier-bij-verbouwing-van-het-eigen-binnenhof%7Eb7418d58/&psig=AOvVaw3oT6FZhvwDeQ51U__tPh-b&ust=1559042897002260

(1) Are we doing well ? (online access)

88%

50%Any form of online contact with HC provider

E-consultation 55% 22%

Video consultation 2% 26%

Make an online appoinment 53% 23%

Primary care Secondary care

eHealth monitor 2019, RIVM, NICTIZ

(2) Are we doing well ? (self-management / personal health environments)

64%Seeks information on internet

Uses internet to decide to consult a GP 37%

Tracking of physical activity

Yes 14%

Tracking health (general)

34%

Any user

eHealth monitor 2019, RIVM, NICTIZ

Chronic disease

Yes 10%

(3) Are we doing well ? (remote support)

47% 37%Telemonitoring

Personal alarm

Movement sensors

GPS trackers / door sensors

Primary care Secondary care

eHealth monitor 2019, RIVM, NICTIZ

14%

87%

66%

23%

Nursing home / elderly care

Care robots 10%

Dutch Innovation ecosystem

Worlds most concentrated Life Sciences & Health cluster • Worldwide #1 for number of medical technology patents • #1 EuroHealth Consumer Index 2014, 2015, 2016, 2017 • 3rd for number of biotechnology patents • 7th for number of pharmaceutical patents • Areas and diseases of focus include:

• Biopharmaceuticals • Biotech • Molecular imaging • Medical technology • e-Health • One Health

• Biomaterials and regenerative medicine • Biobanking • Vaccines • Oncology • Cardiovascular diseases • Health systems and research infrastructure

Life Sciences & Health cluster

Regional Health Innovation hubs

Health Hub Utrecht – Healthy Urban Living

Utrecht region

• Most highly educated workforce in the Netherlands: 46% of working population has a university degree

• 8 million skilled employees within an hour’s travel of Utrecht.

• Life science and health community: 1,700 researchers and 1,750 PhD candidates

The Utrecht region has been ranked the most competitive place on the European

mainland by the European Commission since 2010

Health Hub Utrecht

• Most highly educated workforce in the Netherlands: 46% of working population has a university degree

• 8 million skilled employees within an hour’s travel of Utrecht.

• Life science and health community: 1,700 researchers and 1,750 PhD candidates

27,200 jobs 108 companies 51.500 students

Health Hub Utrecht

Community-focused prevention

(lifestyle, health literacy etc.)

A dynamic regio-alliance that aims at highlighting ‘the sense of urgency’ (increasing costs and lack of personnel) and ‘the sense of opportunity’ (unique regional proposition)

Digital transformation

(eHealth, personal health environments, serious

games)

Attractive job market

(professional development,

leadership)

Innovation journey – an iterative multi-stakeholder proces

Idea Research | Development | Validation Commercialisation Or implementation

Scaling up

Science-based & user centered development

Innovation journey - a bumpy road

EFFECTIVE

USED

REACH

? ? ?

Health benefits Cost-effectiveness

Many innovation are not effective, are not used or do not reach limited value for patients professionals and society

Systematic flaws, fragmentation and limited streamlining of the innovation process

Researcher Professional User Designer Techno- logical/ ICT

Entre- preneurial

There’s an urgent need for

• Faster and better available science • Flexible methodology & tailored

scientific services • …that are offered agile through

public-private partnerships

The Healthcare Innovation Center

Access to patients

Network of experts

Experience and cases