Development of a combined microPET®-MR system
Alun Lucas1, Rob Hawkes1, Pedro Guerra1, Richard Ansorge1,Stefan Siegel2, Robert Nutt2,
John Clark1, Tim Fryer1, Adrian Carpenter1
1University of Cambridge2Siemens Molecular Imaging, USA
CAMBRIDGEUNIVERSITY OF
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Outline:1. Concept
take ‘state-of-art’ multi-ring microPET® Focus120minimize modification and/or compromise to PETuncompromised MRsimultaneous PET-MR
2. Confirm the ‘basics’‘long’ fibersPMTs in magnetic fieldsMR performance
3. ‘Hot off the press’steps toward commissioning the system.
4. And next…
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
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Fit complete PET detector ring into gap in magnet
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
microPET Focus120 novel 1T magnet
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12 x 12 LSO crystals1.5 x 1.5 x 10 mm each
4 detector blocksin each ‘module’
96 detector blocksin the entire system
microPET® Focus™ 120
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
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Concept:
1. Magnet with ‘gap’ to accommodate PET
manipulate magnetic field remotelynovel 1T superconducting magnet with 80mm gap
2. Use well-developed and established PMT technology
extend fiber bundles between LSO crystal and PMT to ~120 cm
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
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CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
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‘Hot off the press’: features of system design
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CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
‘Hot off the press’: features of system design
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CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
‘Hot off the press’: MR hardware
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CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
~53.9 Signal-to-noise ~45.7
PET off PET on
‘Hot off the press’: MR performance
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CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
‘Hot off the press’:
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FDOPA + MR Next steps:
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
‘Move toward demonstratingpre-clinical utility of simultaneous PET-MR’
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Thanks to:
Concorde-CTI/Siemens Molecular Imaging
BrukerGlaxoSmithKline
Funding
EPSRC (Grant number EP/C009096/1)
This study was funded in part by the EC-FP6-project DiMI,LSHB-CT-2005-512146
CAMBRIDGEUNIVERSITY OF
Development of a combined microPET®-MR systemAlun Lucas et al.
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![Monte Carlo simulation of the microPET FOCUS system for small …projects.itn.pt/AF_FCT09/JAN05.pdf · 2009. 12. 3. · platform [1] based on the Geant4 toolkit package and dedicated](https://static.documents.pub/doc/80x56/5fe0da3ccb148a1bc8221f4b/monte-carlo-simulation-of-the-micropet-focus-system-for-small-2009-12-3-platform.jpg)
