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Viewing 1360 publicationsExport to Excel (http://www.niehs.nih.gov//portfolio/index.cfm/portfolio/sciencecodepubs/sc/06,07,08,09,10,11,12/topic/5.8/format/excel)
Publication Title Authors GrantNumber(s)
Journal (Pub date) PubMedLink
PubYear
Blood DNA methylation biomarkers of cumulativelead exposure in adults.
Colicino, Elena; Just,Allan;Kioumourtzoglou,Marianthi-Anna;Vokonas, Pantel;Cardenas, Andre ...
P30ES000002,P30ES009089,P30ES023515,R01ES025225,R01ES027747,R01ES028805
J Expo Sci EnvironEpidemiol (2021 Feb)
31636367
2021
Genetically Increased Telomere Length andAging-Related Traits in the U.K. Biobank.
Demanelis, Kathryn;Tong, Lin; Pierce,Brandon L
R35ES028379 J Gerontol A Biol Sci MedSci (2021 Jan 01)
31603979
2021
Gestational perfluoroalkyl substance exposure andbody mass index trajectories over the first 12 yea ...
Braun, Joseph M; Eliot,Melissa; Papandonatos,George D; Buckley,Jessie P; Cecil, Kim M;Kalkw ...
R01ES025214,R01ES027224,R01ES030078,R01ES030078,R01ES030078,R01ES030078
Int J Obes (Lond) (2021Jan)
33208860
2021
Investigation of Break-Induced Replication in Yeast. Osia, Beth; Elango,Rajula; Kramara, Juraj;Roberts, Steven A;Malkova, Anna
R21ES030307 Methods Mol Biol (2021) 32840789
2021
Noninvasive Assessment of Epidermal GenomicMarkers of UV Exposure in Skin.
Muradova, Elnara;Patel, Nishit; Sell,Brittney; Bittencourt,Bruna B; Ojeda, SandraS; Adelman ...
R01ES030562 J Invest Dermatol (2021Jan)
32553564
2021
PCB126 Exposure Revealed Alterations in m6A RNAModifications in Transcripts Associated With AHRAct ...
Aluru, Neelakanteswar;Karchner, Sibel I
P01ES028938,R01ES024915,R01ES024915
Toxicol Sci (2021 Jan 06) 33064826
2021
Per- and polyfluoroalkyl substance mixtures andgestational weight gain among mothers in the Health ...
Romano, Megan E;Gallagher, Lisa G;Eliot, Melissa N;Calafat, Antonia M;Chen, Aimin; Yolton, ...
P30ES013508,R01ES025214
Int J Hyg Environ Health(2021 Jan)
33181449
2021
Production and Analysis of Human Primordial GermCell-Like Cells.
Mitsunaga, Shino;Shioda, Keiko; Hanna,Jacob H; Isselbacher,Kurt J; Shioda, Toshi
R01ES023316,R01ES023316
Methods Mol Biol (2021) 32852762
2021
Transcriptomic and Epigenetic Preservation of GeneticSex Identity in Estrogen-feminized Male Chicke ...
Shioda, Keiko;Odajima, Junko;Kobayashi, Misato;Kobayashi, Mutsumi;Cordazzo, Bianca;Isselba ...
R01ES020454,R01ES020454,R01ES023316,R01ES023316
Endocrinology (2021 Jan01)
33170207
2021
A map of cis-regulatory elements and 3D genomestructures in zebrafish.
Yang, Hongbo; Luan,Yu; Liu, Tingting; Lee,Hyung Joo; Fang, Li;Wang, Yanli; Wang,Xiaotao; ...
U24ES026699 Nature (2020 Dec) 33239788
2020
A naturally-occurring 22-bp coding deletion inUgt86Dd reduces nicotine resistance in Drosophilamel ...
Macdonald, Stuart J;Highfill, Chad A
R01ES029922 BMC Res Notes (2020 Mar30)
32228671
2020
A Positive Feedback Loop Between c-MycUpregulation, Glycolytic Shift, and HistoneAcetylation Enhan ...
Clementino, Marco;Xie, Jie; Yang, Ping; Li,Yunfei; Lin, Hsuan-Pei;Fenske, William K;Tao, ...
R01ES026151,R01ES029942
Toxicol Sci (2020 09 01) 32525551
2020
A precision medicine approach to defining the impactof doxorubicin on the bioenergetic-metabolite i ...
Smith, Matthew Ryan;Chacko, Balu K;Johnson, Michelle S;Benavides, Gloria A;Uppal, Karan; Go ...
P30ES019776,R01ES023485,U2CES026560
Redox Biol (2020 01) 31546171
2020
A Robust Method Uncovers SignificantContext-Specific Heritability in Diverse ComplexTraits.
Dahl, Andy; Nguyen,Khiem; Cai, Na;Gandal, Michael J;Flint, Jonathan; Zaitlen,Noah
R01ES029929 Am J Hum Genet (2020 0102)
31901249
2020
A special issue dedicated to Dr. Bruce N. Ames:Introduction.
Walker, Graham C R35ES028303 Mutat Res (2020 01) 32087846
2020
A stapled POL κ peptide targets REV1 to inhibitmutagenic translesion synthesis.
Chatterjee, Nimrat;D'Souza, Sanjay;Shabab, Mohammad;Harris, Cynthia A;Hilinski, Gerard J; V ...
P30ES002109,R35ES028303
Environ Mol Mutagen(2020 10)
32573829
2020
A vision for exposome epidemiology: The pregnancyexposome in relation to breast cancer in the Child ...
Jones, Dean P; Cohn,Barbara A
P30ES019776,R01ES023485,U2CES026560,U2CES030163
Reprod Toxicol (2020 03) 32197999
2020
Accelerated epigenetic aging as a risk factor forchronic obstructive pulmonary disease and decrease ...
Breen, Miyuki;Nwanaji-Enwerem,Jamaji C; Karrasch,Stefan; Flexeder,Claudia; Schulz,Holger; ...
R01ES025225,R01ES027747
Aging (Albany NY) (202008 03)
32747609
2020
Activation of β-Catenin Signaling and its CrosstalkWith Estrogen and Histone Deacetylases in Human ...
Ali, Mohamed; Shahin,Sara Mahmoud; Sabri,Nagwa Ali; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 J Clin Endocrinol Metab(2020 04 01)
31761932
2020
Activity profiling and crystal structures ofinhibitor-bound SARS-CoV-2 papain-like protease: Afram ...
Rut, Wioletta; Lv,Zongyang; Zmudzinski,Mikolaj; Patchett,Stephanie; Nayak,Digant; Snipas, ...
R01ES025166 Sci Adv (2020 10) 33067239
2020
Adipose tissue-liver crosstalk during pathologicchanges caused by vinyl chloride metabolites in mic ...
Kaelin, Brenna R;McKenzie, Collin M;Hempel, Karl W; Lang,Anna L; Arteel, GavinE; Beier, Ju ...
R21ES031531 Toxicol Appl Pharmacol(2020 07 15)
32445754
2020
Agrochemicals and obesity. Ren, Xiao-Min; Kuo,Yun; Blumberg, Bruce
R01ES023316,R01ES023316
Mol Cell Endocrinol (202009 15)
32619583
2020
Alcohol Consumption and Risk of Uterine Fibroids. Takala, Hajra; Yang,Qiwei; El Razek,Ahmed M Abd; Ali,Mohamed; Al-Hendy,Ayman
R01ES028615 Curr Mol Med (2020) 31612831
2020
An Evolutionary Insertion in the Mxra8Receptor-Binding Site Confers Resistance toAlphavirus Infect ...
Kim, Arthur S;Zimmerman, Ofer; Fox,Julie M; Nelson,Christopher A; Basore,Katherine; Zhang, ...
U24ES026699 Cell Host Microbe (202003 11)
32075743
2020
An introduction for the special issue on environmentalhealth and genome integrity.
Yan, Shan; Vaziri,Cyrus
R01ES029079 Environ Mol Mutagen(2020 08)
32683747
2020
Analysis of Telomere Length and Aberrations byQuantitative FISH.
Fouquerel, Elise;Opresko, Patricia
R00ES027028 Methods Mol Biol (2020) 31989559
2020
AP-endonuclease 1 sculpts DNA through an anchoringtyrosine residue on the DNA intercalating loop.
Hoitsma, Nicole M;Whitaker, Amy M;Beckwitt, Emily C;Jang, Sunbok; Agarwal,Pratul K; Van Hou ...
R01ES029203 Nucleic Acids Res (202007 27)
32542366
2020
Arsenic and benzo[a]pyrene co-exposure actssynergistically in inducing cancer stem cell-like proper...
Wang, Zhishan; Yang,Ping; Xie, Jie; Lin,Hsuan-Pei; Kumagai,Kazuyoshi; Harkema,Jack; Yang, ...
P30ES026529,R01ES028256
Environ Int (2020 04) 32062438
2020
Arsenic Exposure and Compromised Protein QualityControl.
Tam, Lok Ming; Wang,Yinsheng
R35ES031707 Chem Res Toxicol (2020Jul 20)
32410444
2020
Arsenic-induced changes in miRNA expression incancer and other diseases.
Ferragut Cardoso, AnaP; Udoh, Karen T;States, J Christopher
P30ES030283,R01ES027778
Toxicol Appl Pharmacol(2020 12 15)
33127375
2020
Arsenite Binds to ZNF598 to PerturbRibosome-Associated Protein Quality Control.
Tam, Lok Ming; Jiang,Ji; Wang, Pengcheng;Wang, Yinsheng
R35ES031707 Chem Res Toxicol (2020Jul 20)
32324387
2020
Arsenite Exposure Displaces Zinc from ZRANB2Leading to Altered Splicing.
Banerjee, Mayukh;Ferragut Cardoso, AnaP; Lykoudi, Angeliki;Wilkey, Daniel W; Pan,Jianmin; W ...
R01ES027778 Chem Res Toxicol (2020Jun 15)
32274925
2020
Asbestos induces mesothelial cell transformation viaHMGB1-driven autophagy.
Xue, Jiaming;Patergnani, Simone;Giorgi, Carlotta;Suarez, Joelle; Goto,Keisuke; Bononi, Ang...
R01ES030948 Proc Natl Acad Sci U S A(2020 10 13)
32999071
2020
Assessing the impact of arsenic metabolism efficiencyon DNA methylation using Mendelian randomizati ...
DiGiovanni, Anthony;Demanelis, Kathryn;Tong, Lin; Argos,Maria; Shinkle, Justin;Jasmine, Fa ...
R35ES028379 Environ Epidemiol (2020Apr)
32337471
2020
Association of Neutrophil to Lymphocyte Ratio WithPulmonary Function in a 30-Year Longitudinal Stud ...
Gao, Xu; Coull, Brent;Lin, Xihong; Vokonas,Pantel; Sparrow, David;Hou, Lifang; DeMeo,Dawn ...
P30ES009089,R01ES025225,R01ES027747
JAMA Netw Open (202007 01)
32658288
2020
Associations between attention deficit hyperactivitydisorder symptoms and eating behaviors in early ...
Fuemmeler, Bernard F;Sheng, Yaou;Schechter, Julia C; Do,Elizabeth; Zucker,Nancy; Majors, A ...
R24ES028531 Pediatr Obes (2020 07) 32119190
2020
Associations between maternal obesity, gestationalcytokine levels and child obesity in the NEST coh ...
Maguire, Rachel L;House, John S; Lloyd,Dillon T; Skinner,Harlyn G; Allen,Terrence K; Raffi, ...
P30ES025128,R24ES028531
Pediatr Obes (2020 Dec30)
33381912
2020
Associations of annual ambient PM2.5 componentswith DNAm PhenoAge acceleration in elderly men:The ...
Wang, Cuicui;Koutrakis, Petros; Gao,Xu; Baccarelli, Andrea;Schwartz, Joel
P30ES009089,R01ES025225,R01ES027747
Environ Pollut (2020 Mar) 31818625
2020
Associations of smoking and air pollution withperipheral blood RNA N6-methyladenosine in theBeijin ...
Kupsco, Allison;Gonzalez, Gwendolyn;Baker, Brennan H;Knox, Julia M; Zheng,Yinan; Wang, She ...
P30ES009089,R01ES025121,R01ES025225,R01ES027845,T32ES007322
Environ Int (2020 11) 32791345
2020
Asymmetric repair of UV damage in nucleosomesimposes a DNA strand polarity on somatic mutationsin ...
Mao, Peng; Smerdon,Michael J; Roberts,Steven A; Wyrick, JohnJ
R01ES028698 Genome Res (2020 01) 31871068
2020
Atypical UV Photoproducts Induce Non-canonicalMutation Classes Associated with Driver Mutations in...
Laughery, Marian F;Brown, Alexander J;Bohm, Kaitlynne A;Sivapragasam, Smitha;Morris, Haley ...
R01ES028698,R21ES029655
Cell Rep (2020 Nov 17) 33207206
2020
Biomarkers of aging and lung function in thenormative aging study.
Wang, Cuicui; Just,Allan; Heiss, Jonathan;Coull, Brent A; Hou,Lifang; Zheng, Yinan;Sparrow ...
P30ES000002,P30ES009089,R01ES025225,R01ES027747
Aging (Albany NY) (202006 19)
32561690
2020
Cancer Risks Associated With Germline PALB2Pathogenic Variants: An International Study of 524Famil ...
Yang, Xin; Leslie,Goska; Doroszuk,Alicja; Schneider,Sandra; Allen, Jamie;Decker, Brennan; ...
R01ES027121 J Clin Oncol (2020 03 01) 31841383
2020
Catalytic mechanism of the mismatch-specific DNAglycosylase methyl-CpG-binding domain 4.
Ouzon-Shubeita, Hala;Jung, Hunmin; Lee,Michelle H; Koag,Myong-Chul; Lee,Seongmin
R01ES026676 Biochem J (2020 05 15) 32297632
2020
Cell Types in Environmental Epigenetic Studies:Biological and Epidemiological Frameworks.
Campbell, Kyle A;Colacino, Justin A;Park, Sung Kyun;Bakulski, Kelly M
P30ES017885,P42ES017198,R01ES025531,R01ES025574,R01ES028802,R01ES028802,R01ES028802,R01ES028802,U01ES026697
Curr Environ Health Rep(2020 09)
32794033
2020
Cell-type-specific 3D epigenomes in the developinghuman cortex.
Song, Michael;Pebworth, Mark-Phillip;Yang, Xiaoyu; Abnousi,Armen; Fan, Changxu;Wen, Jia; R ...
U24ES026699 Nature (2020 Nov) 33057195
2020
Cellular diversity of the regenerating caudal fin. Hou, Yiran; Lee, HyungJoo; Chen, Yujie; Ge,Jiaxin; Osman, FujrOsman Ibrahim;McAdow, Anthon ...
U24ES026699 Sci Adv (2020 Aug) 32851162
2020
Certain ortho-hydroxylated brominated ethers arepromiscuous kinase inhibitors that impair neuronal ...
Poston, Robert G;Murphy, Lillian;Rejepova, Ayna;Ghaninejad-Esfahani,Mina; Segales, Joshua;...
R01ES028738 J Biol Chem (2020 05 01) 32229587
2020
Characterization of long G4-rich enhancer-associatedgenomic regions engaging in a novel loop:loop ' ...
Williams, Jonathan D;Houserova, Dominika;Johnson, Bradley R;Dyniewski, Brad;Berroyer, Alexa ...
R01ES030084,R01ES030084
Nucleic Acids Res (202006 19)
32383760
2020
Chemical mixtures and neurobehavior: a review ofepidemiologic findings and future directions.
Vuong, Ann M; Yolton,Kimberly; Braun,Joseph M; Lanphear,Bruce P; Chen, Aimin
P30ES013508,R01ES025214
Rev Environ Health (2020Sep 25)
32598325
2020
Chromatin remodeling and mismatch repair: Accessand excision.
Goellner, Eva M R00ES026653 DNA Repair (Amst) (202001)
31698199
2020
Chromosomal alterations among age-relatedhaematopoietic clones in Japan.
Terao, Chikashi;Suzuki, Akari;Momozawa, Yukihide;Akiyama, Masato;Ishigaki, Kazuyoshi;Yamam ...
DP2ES030554 Nature (2020 08) 32581364
2020
Chronic and acute arsenic exposure enhance EGFRexpression via distinct molecular mechanisms.
Kim, Christine; States,J Christopher; Ceresa,Brian P
R01ES027778,T32ES011564
Toxicol In Vitro (2020Sep)
32599262
2020
Chronic exposure to cadmium induces a malignanttransformation of benign prostate epithelial cells.
Chandrasekaran, Balaji;Dahiya, Nisha R; Tyagi,Ashish; Kolluru,Venkatesh; Saran,Uttara; Baby ...
R01ES027778,R01ES028102,R01ES030019
Oncogenesis (2020 Feb 17) 32066655
2020
Co-opted transposons help perpetuate conservedhigher-order chromosomal structures.
Choudhary, MayankNk; Friedman, Ryan Z;Wang, Julia T; Jang,Hyo Sik; Zhuo, Xiaoyu;Wang, Ting
U24ES026699 Genome Biol (2020 01 24) 31973766
2020
CofActor: A light- and stress-gated optogeneticclustering tool to study disease-associated cytoskel ...
Salem, Fatema B;Bunner, Wyatt P;Prabhu, Vishwanath V;Kuyateh, Abu-Bakarr;O'Bryant, Collin T ...
R15ES029673,R15ES029673,R15ES029673,R15ES029673
J Biol Chem (2020 08 07) 32424038
2020
Collision-Induced Dissociation Studies of ProtonatedIons of Alkylated Thymidine and 2'-Deoxyguanosi ...
Cui, Yuxiang; Yuan,Jun; Wang, Pengcheng;Wu, Jun; Yu, Yang;Wang, Yinsheng
R01ES029749 J Am Soc Mass Spectrom(2020 Apr 01)
32134268
2020
Comparison of differential accessibility analysisstrategies for ATAC-seq data.
Gontarz, Paul; Fu,Shuhua; Xing,Xiaoyun; Liu,Shaopeng; Miao,Benpeng; Bazylianska,Viktoriia ...
U24ES026699 Sci Rep (2020 06 23) 32576878
2020
Comparison of the Base Excision and Direct ReversalRepair Pathways for Correcting 1,N6-Ethenoadenin ...
Caffrey, Paul J; Kher,Raadhika; Bian, Ke; Li,Deyu; Delaney, Sarah
R01ES028865,R01ES028865
Chem Res Toxicol (2020Jul 20)
32293880
2020
Comprehensive Molecular Characterization IdentifiesDistinct Genomic and Immune Hallmarks of Renal M...
Msaouel, Pavlos;Malouf, Gabriel G; Su,Xiaoping; Yao, Hui;Tripathi, Durga N;Soeung, Melinda ...
R01ES029680 Cancer Cell (2020 05 11) 32359397
2020
Comprehensive structure-function characterization ofDNMT3B and DNMT3A reveals distinctive de novoD ...
Gao, Linfeng; Emperle,Max; Guo, Yiran;Grimm, Sara A; Ren,Wendan; Adam,Sabrina; Uryu, Hide ...
R35ES031707 Nat Commun (2020 07 03) 32620778
2020
Concentration-response evaluation of ToxCastcompounds for multivariate activity patterns of neural...
Kosnik, Marissa B;Strickland, Jenna D;Marvel, Skylar W;Wallis, Dylan J;Wallace, Kathleen; R ...
P30ES025128,R56ES030007
Arch Toxicol (2020 02) 31822930
2020
Concentrations and loadings of organophosphate andreplacement brominated flame retardants in house ...
Percy, Zana; LaGuardia, Mark J; Xu,Yingying; Hale, RobertC; Dietrich, Kim N;Lanphear, Bruc ...
P30ES006096,R01ES025214,R01ES027224
Chemosphere (2020 Jan) 31499316
2020
Content and Performance of the MiniMUGAGenotyping Array: A New Tool To Improve Rigor andReproducib ...
Sigmon, JohnSebastian; Blanchard,Matthew W; Baric,Ralph S; Bell, TimothyA; Brennan, Jennife ...
P42ES031007,R01ES029925
Genetics (2020 Dec) 33067325
2020
Copper associates with differential methylation inplacentae from two US birth cohorts.
Kennedy, Elizabeth;Everson, Todd M;Punshon, Tracy;Jackson, Brian P; Hao,Ke; Lambertini, Lu ...
P30ES019776,R01ES025145,R01ES025145,R24ES028507
Epigenetics (2020 03) 31462129
2020
Cross-linking of the DNA repair proteinO6-alkylguanine DNA alkyltransferase to DNA in thepresence ...
Ming, Xun;Michaelson-Richie,Erin D; Groehler 4th,Arnold S; Villalta, PeterW; Campbell, Coli ...
R01ES023350 DNA Repair (Amst) (202005)
32283495
2020
DeepH&M: Estimating single-CpGhydroxymethylation and methylation levels fromenrichment and restric ...
He, Yu; Jang, Hyo Sik;Xing, Xiaoyun; Li,Daofeng; Vasek,Michael J; Dougherty,Joseph D; Wang ...
U24ES026699 Sci Adv (2020 Jul) 32937429
2020
Defective postreplication repair of UV photoproductsin melanoma: a mutator phenotype.
Brash, Douglas E;Seidman, Michael M
R01ES030562 Mol Oncol (2020 01) 31821728
2020
Derivation of stable embryonic stem cell-like, buttranscriptionally heterogenous, induced pluripote ...
Garbutt, Tiffany A;Konganti, Kranti;Konneker, Thomas;Hillhouse, Andrew;Phelps, Drake; Jones ...
U01ES026717 Mamm Genome (2020 12) 33015751
2020
Derivation of trophoblast stem cells from naïve humanpluripotent stem cells.
Dong, Chen; Beltcheva,Mariana; Gontarz, Paul;Zhang, Bo; Popli,Pooja; Fischer, Laura A;Khan ...
U24ES026699 Elife (2020 Feb 12) 32048992
2020
Detection and Discrimination of DNA AdductsDiffering in Size, Regiochemistry, and FunctionalGroup ...
Nookaew, Intawat;Jenjaroenpun, Piroon;Du, Hua; Wang,Pengcheng; Wu, Jun;Wongsurawat, Thidat ...
R01ES029749 Chem Res Toxicol (2020Dec 21)
32799528
2020
Determinants of telomere length across human tissues.
Demanelis, Kathryn;Jasmine, Farzana; Chen,Lin S; Chernoff,Meytal; Tong, Lin;Delgado, Dayan ...
P30ES027792,R35ES028379
Science (2020 09 11) 32913074
2020
Deubiquitinase USP7-mediated MCL-1 up-regulationenhances Arsenic and Benzo(a)pyrene co-exposure-ind...
Yang, Ping; Xie, Jie; Li,Yunfei; Lin, Hsuan-Pei;Fenske, William;Clementino, Marco;Jiang, ...
R01ES028256 Theranostics (2020) 32802178
2020
Development of a DNA Adductome Mass SpectralDatabase.
Guo, Jingshu; Turesky,Robert J; Tarifa,Anamary; DeCaprio,Anthony P; Cooke,Marcus S; Walmsle ...
R01ES019564,R03ES031188
Chem Res Toxicol (202004 20)
32223224
2020
Developmental Exposure to PCB153(2,2',4,4',5,5'-Hexachlorobiphenyl) Alters CircadianRhythms and th ...
Aluru, Neelakanteswar;Krick, Keegan S;McDonald, Adriane M;Karchner, Sibel I
R01ES024915,R01ES024915
Toxicol Sci (2020 01 01) 31621872
2020
Developmental origins of transgenerational spermhistone retention following ancestral exposures.
Ben Maamar, Millissia;Beck, Daniel; Nilsson,Eric; McCarrey, JohnR; Skinner, Michael K
R01ES012974,R01ES012974
Dev Biol (2020 Sep 01) 32628935
2020
Differential contribution of bone marrow-derivedinfiltrating monocytes and resident macrophages to ...
Gangwar, RoopeshSingh; Vinayachandran,Vinesh; Rengasamy,Palanivel; Chan, Ricky;Park, Bongso ...
R01ES019616,U01ES026721
Sci Rep (2020 09 01) 32873817
2020
DNA polymerase δ proofreads errors made by DNApolymerase ε.
Bulock, Chelsea R;Xing, Xuanxuan;Shcherbakova, Polina V
R01ES015869 Proc Natl Acad Sci U S A(2020 03 17)
32123096
2020
DNA-protein crosslinks are repaired via homologousrecombination in mammalian mitochondria.
Chesner, Lisa N;Essawy, Maram;Warner, Cecilia;Campbell, Colin
R01ES023350 DNA Repair (Amst) (2020Nov 25)
33316746
2020
Dual genome-wide CRISPR knockout and CRISPRactivation screens identify mechanisms that regulatethe ...
Schleicher, Emily M;Dhoonmoon, Ashna;Jackson, Lindsey M;Clements, Kristen E;Stump, Coryn L; ...
R01ES026184 PLoS Genet (2020 11) 33137164
2020
Dynamic action of DNA repair proteins as revealed bysingle molecule techniques: Seeing is believing ...
Kong, Muwen;Beckwitt, Emily C; VanHouten, Bennett
R35ES031638 DNA Repair (Amst) (202009)
33087275
2020
Dynamic single-cell intracellular pH sensing using aSERS-active nanopipette.
Guo, Jing; SesenaRubfiaro, Alberto; Lai,Yanhao; Moscoso,Joseph; Chen, Feng;Liu, Yuan; Wang ...
R01ES023569 Analyst (2020 Jul 21) 32542257
2020
Dysregulations of Functional RNA Modifications inCancer, Cancer Stemness and Cancer Therapeutics.
Uddin, MohammadBurhan; Wang,Zhishan; Yang,Chengfeng
R01ES026151,R01ES028256,R01ES029496,R01ES029942
Theranostics (2020) 32194861
2020
Efficient Estimation and Applications ofCross-Validated Genetic Predictions to Polygenic RiskScore ...
Mefford, Joel; Park,Danny; Zheng, Zhili;Ko, Arthur;Ala-Korpela, Mika;Laakso, Markku; Pajuk...
R01ES029929 J Comput Biol (2020 04) 32077750
2020
Elagolix Treatment for Up to 12 Months in WomenWith Heavy Menstrual Bleeding and UterineLeiomyomas ...
Simon, James A;Al-Hendy, Ayman;Archer, David F;Barnhart, Kurt T;Bradley, Linda D; Carr,Br ...
R01ES028615 Obstet Gynecol (2020 06) 32459423
2020
Electron microscopic characterization of exhaustparticles containing lead dibromide beads expelled ...
Griffith, Jack D R01ES031635 Atmos Pollut Res (2020Sep)
33100835
2020
Endogenous itaconate is not required for particulatematter-induced NRF2 expression or inflammatory ...
Sun, Kaitlyn A; Li,Yan; Meliton, AngeloY; Woods, Parker S;Kimmig, Lucas M;Cetin-Atalay, Re ...
P30ES027792,R01ES015024,U01ES026718
Elife (2020 Apr 07) 32255424
2020
Engineered unnatural ubiquitin for optimal detectionof deubiquitinating enzymes.
Rut, Wioletta;Zmudzinski, Mikolaj;Snipas, Scott J; Bekes,Miklos; Huang, Tony T;Drag, Marci ...
R01ES025166 Chem Sci (2020 Jun 21) 32953009
2020
Environmental determinants of cardiovascular disease:lessons learned from air pollution.
Al-Kindi, Sadeer G;Brook, Robert D;Biswal, Shyam;Rajagopalan, Sanjay
R01ES019616,U01ES026721
Nat Rev Cardiol (2020 10) 32382149
2020
Environmental Obesogens and Their Impact onSusceptibility to Obesity: New Mechanisms andChemicals.
Egusquiza, RiannJenay; Blumberg, Bruce
R01ES023316,R01ES023316
Endocrinology (2020 0301)
32067051
2020
Environmental Pollution and the DevelopmentalOrigins of Childhood Liver Disease.
Cave, Matthew C P30ES030283,P42ES023716,R21ES031510,R35ES028373,R35ES028373
Hepatology (2020 Nov) 32910501
2020
Epigenetic transgenerational inheritance ofparent-of-origin allelic transmission of outcross pathol...
Ben Maamar, Millissia;King, Stephanie E;Nilsson, Eric; Beck,Daniel; Skinner,Michael K
R01ES012974,R01ES012974
Dev Biol (2020 02 01) 31682807
2020
Epigenome environment interactions accelerateepigenomic aging and unlock metabolically restricted e...
Treviño, Lindsey S;Dong, Jianrong;Kaushal, Ahkilesh;Katz, Tiffany A; Jangid,Rahul Kumar; Ro ...
P30ES030285,U01ES026719
Nat Commun (2020 05 08) 32385268
2020
Epigenome-wide association study fortransgenerational disease sperm epimutationbiomarkers followin ...
Ben Maamar, Millissia;Nilsson, Eric; Thorson,Jennifer L M; Beck,Daniel; Skinner,Michael K
R01ES012974,R01ES012974
Reprod Toxicol (2020Dec)
32905848
2020
Epigenomics and genotype-phenotype associationanalyses reveal conserved genetic architecture of com...
Liu, Shuli; Yu, Ying;Zhang, Shengli; Cole,John B; Tenesa, Albert;Wang, Ting; McDaneld,Tar ...
U24ES026699 BMC Biol (2020 07 03) 32620158
2020
Expanding molecular roles of UV-DDB: Shining lighton genome stability and cancer.
Beecher, Maria; Kumar,Namrata; Jang, Sunbok;Rapić-Otrin, Vesna;Van Houten, Bennett
R35ES031638 DNA Repair (Amst) (202010)
32739133
2020
Exploring the coronavirus pandemic with the WashUVirus Genome Browser.
Flynn, Jennifer A;Purushotham, Deepak;Choudhary, Mayank NK; Zhuo, Xiaoyu; Fan,Changxu; Matt ...
U24ES026699 Nat Genet (2020 10) 32908257
2020
Exposure to Air Pollution Disrupts Circadian Rhythmthrough Alterations in Chromatin Dynamics.
Palanivel, Rengasamy;Vinayachandran,Vinesh; Biswal, Shyam;Deiuliis, Jeffrey A;Padmanabhan, ...
R01ES015146,R01ES015146,R01ES019616,U01ES026721
iScience (2020 Nov 20) 33241196
2020
Exposures to chemical mixtures during pregnancy andneonatal outcomes: The HOME study.
Kalloo, Geetika;Wellenius, Gregory A;McCandless, Lawrence;Calafat, Antonia M;Sjodin, Andrea ...
R01ES025214 Environ Int (2020 01) 31726361
2020
Extracellular NAD+ enhances PARP-dependent DNArepair capacity independently of CD73 activity.
Wilk, Anna; Hayat,Faisal; Cunningham,Richard; Li, Jianfeng;Garavaglia, Silvia;Zamani, Leil ...
R01ES014811,U01ES029518,U01ES029518
Sci Rep (2020 01 20) 31959836
2020
EZH2 has a non-catalytic and PRC2-independent rolein stabilizing DDB2 to promote nucleotide excisio ...
Koyen, Allyson E;Madden, Matthew Z;Park, Dongkyoo;Minten, Elizabeth V;Kapoor-Vazirani, Priy...
U01ES029520 Oncogene (2020 06) 32457468
2020
FANCJ compensates for RAP80 deficiency andsuppresses genomic instability induced by interstrandcro ...
Awate, Sanket;Sommers, Joshua A;Datta, Arindam; Nayak,Sumeet; Bellani, MarinaA; Yang, Oliv ...
R01ES026184 Nucleic Acids Res (202009 18)
32797166
2020
Fluorescence Sheds Light on DNA Damage, DNARepair, and Mutations.
Owiti, Norah A; Nagel,Zachary D; Engelward,Bevin P
P42ES027707,U01ES029520,U44ES024698
Trends Cancer (2020 Nov14)
33203608
2020
Functional Characterization of TMEM127 VariantsReveals Novel Insights into Its Membrane Topologyan ...
Flores, Shahida K;Deng, Yilun; Cheng,Ziming; Zhang, Xingyu;Tao, Sifan; Saliba, Afaf;Chu, ...
R01ES031522 J Clin Endocrinol Metab(2020 Sep 01)
32575117
2020
Functions of the major abasic endonuclease (APE1) incell viability and genotoxin resistance.
McNeill, Daniel R;Whitaker, Amy M;Stark, Wesley J; Illuzzi,Jennifer L; McKinnon,Peter J; Fr ...
R01ES029203 Mutagenesis (2020 02 13) 31816044
2020
Gaining a deeper understanding of social determinantsof preterm birth by integrating multi-omics da ...
Hong, Xiumei; Bartell,Tami R; Wang, Xiaobin
R01ES031272,R01ES031521
Pediatr Res (2020 Nov 13) 33188285
2020
Generation and characterization of the Eµ-Irf8 mousemodel.
Qiu, Zhijun; Holder,Kenneth N; Lin,An-Ping; Myers, Jamie;Jiang, Shoulei; Gorena,Karla M; K ...
R01ES031522 Cancer Genet (2020 07) 32535543
2020
Genetic Determinants of Reduced Arsenic MetabolismEfficiency in the 10q24.32 Region Are Associated ...
Chernoff, Meytal; Tong,Lin; Demanelis,Kathryn; VanderGriend, Donald; Ahsan,Habib; Pierce, ...
R35ES028379 Toxicol Sci (2020 08 01) 32433756
2020
Genetic evidence for reconfiguration of DNApolymerase θ active site for error-free translesion synt...
Yoon, Jung-Hoon;Johnson, Robert E;Prakash, Louise;Prakash, Satya
R01ES022948 J Biol Chem (2020 05 01) 32169903
2020
Genetically predicted telomere length is associatedwith clonal somatic copy number alterations in p ...
Brown, Derek W; Lin,Shu-Hong; Loh, Po-Ru;Chanock, Stephen J;Savage, Sharon A;Machiela, Mit ...
DP2ES030554 PLoS Genet (2020 10) 33090998
2020
Genome-wide CRISPR synthetic lethality screenidentifies a role for the ADP-ribosyltransferase PARP1...
Dhoonmoon, Ashna;Schleicher, Emily M;Clements, Kristen E;Nicolae, Claudia M;Moldovan, Georg ...
R01ES026184 Nucleic Acids Res (202007 27)
32542389
2020
Genome-Wide Mapping of UV-Induced DNA Damagewith CPD-Seq.
Mao, Peng; Wyrick,John J
R01ES028698,R21ES029302,R21ES029655
Methods Mol Biol (2020) 32681485
2020
Genome-wide role of Rad26 in promotingtranscription-coupled nucleotide excision repair inyeast chr ...
Duan, Mingrui; Selvam,Kathiresan; Wyrick,John J; Mao, Peng
R01ES028698,R21ES029302,R21ES029655
Proc Natl Acad Sci U S A(2020 08 04)
32690696
2020
Genome-wide single-nucleotide resolution ofoxaliplatin-DNA adduct repair in drug-sensitive and-res ...
Vaughn, Courtney M;Selby, Christopher P;Yang, Yanyan; Hsu,David S; Sancar, Aziz
R01ES027255 J Biol Chem (2020 05 29) 32299912
2020
Getting in Shape for the World's LeadingEnvironmental Risk Factor.
Rajagopalan, Sanjay;Al-Kindi, Sadeer
R01ES019616,U01ES026721
J Am Coll Cardiol (202002 25)
32081279
2020
Hematopoietic mosaic chromosomal alterations andrisk for infection among 767,891 individuals withou ...
Natarajan, Pradeep;Zekavat, Seyedeh; Lin,Shu-Hong; Bick,Alexander; Liu,Aoxing; Paruchuri, ...
DP2ES030554 Res Sq (2020 Nov 16) 33236004
2020
Hematopoietic mosaic chromosomal alterations andrisk for infection among 767,891 individuals withou ...
Zekavat, Seyedeh M;Lin, Shu-Hong; Bick,Alexander G; Liu,Aoxing; Paruchuri,Kaavya; Uddin, M ...
DP2ES030554 medRxiv (2020 Nov 16) 33236019
2020
Hepatic Tumor Formation in Adult MiceDevelopmentally Exposed to Organotin.
Katz, Tiffany A;Grimm, Sandra L;Kaushal, Akhilesh;Dong, Jianrong;Treviño, Lindsey S;Jangid ...
U01ES026719 Environ Health Perspect(2020 01)
31939706
2020
History of DNA polymerase β X-ray crystallography. Whitaker, Amy M;Freudenthal, Bret D
R01ES029203 DNA Repair (Amst) (202009)
33087265
2020
HLTF Promotes Fork Reversal, Limiting ReplicationStress Resistance and Preventing Multiple Mechanis ...
Bai, Gongshi; Kermi,Chames; Stoy,Henriette; Schiltz, CarlJ; Bacal, Julien; Zaino,Angela M; ...
R01ES016486 Mol Cell (2020 06 18) 32442397
2020
HMCES Maintains Replication Fork Progression andPrevents Double-Strand Breaks in Response toAPOBEC ...
Mehta, Kavi P M;Lovejoy, Courtney A;Zhao, Runxiang;Heintzman, Darren R;Cortez, David
R01ES030575 Cell Rep (2020 06 02) 32492421
2020
HMGB1 as a therapeutic target in disease. Xue, Jiaming; Suarez,Joelle S; Minaai,Michael; Li,Shuangjing; Gaudino,Giovanni; Pass, Harv ...
R01ES030948 J Cell Physiol (2020 Oct26)
33107103
2020
Homologous Recombination Repair TruncationsPredict Hypermutation in Microsatellite StableColorecta ...
Lee, Minyi; Eng,George; Barbari,Stephanie R;Deshpande, Vikram;Shcherbakova, PolinaV; Gala, ...
R01ES015869 Clin Transl Gastroenterol(2020 03)
32352724
2020
Human DNA ligases in replication and repair. Sallmyr, Annahita;Rashid, Ishtiaque;Bhandari, SeemaKhattri; Naila, Tasmin;Tomkinson, Alan E
R01ES012512 DNA Repair (Amst) (202009)
33087274
2020
Human XPG nuclease structure, assembly, andactivities with insights for neurodegeneration andcance ...
Tsutakawa, Susan E;Sarker, Altaf H; Ng,Clifford; Arvai, AndrewS; Shin, David S; Shih,Brian ...
R01ES031635 Proc Natl Acad Sci U S A(2020 06 23)
32522879
2020
Hyperactive CDK2 Activity in Basal-like BreastCancer Imposes a Genome Integrity Liability that Can...
Sviderskiy, VladislavO; Blumenberg, Lili;Gorodetsky, Elizabeth;Karakousi, TriantafylliaR; Hi ...
R01ES025166 Mol Cell (2020 11 19) 33152268
2020
Hypoxia Induces Resistance to EGFR Inhibitors inLung Cancer Cells via Upregulation of FGFR1 and the...
Lu, Yuhong; Liu,Yanfeng; Oeck,Sebastian; Zhang, GaryJ; Schramm, Alexander;Glazer, Peter M
R01ES005775 Cancer Res (2020 Nov 01) 32873635
2020
Impact of 1,N6-ethenoadenosine, a damagedribonucleotide in DNA, on translesion synthesis andrepair ...
Ghodke, Pratibha P;Guengerich, F Peter
R01ES026955 J Biol Chem (2020 05 01) 32213600
2020
Impact of hypoxia on DNA repair and genomeintegrity.
Kaplan, Alanna R;Glazer, Peter M
R01ES005775 Mutagenesis (2020 02 13) 31282537
2020
Improved asthma outcomes observed in the vicinity ofcoal power plant retirement, retrofit, and conv ...
Casey, Joan A; Su,Jason G; Henneman,Lucas R F; Zigler,Corwin; Neophytou,Andreas M; Catalano ...
R00ES027023,R00ES027023,R00ES027511,R01ES026217
Nat Energy (2020 May) 32483491
2020
Individual species and cumulative mixturerelationships of 24-hour urine metal concentrationswith D ...
Nwanaji-Enwerem,Jamaji C; Colicino,Elena; Specht, Aaron J;Gao, Xu; Wang, Cuicui;Vokonas, P ...
P30ES009089,R01ES025225,R01ES027747
Environ Res (2020 07) 32361261
2020
Inhibition of base excision repair by natamycinsuppresses prostate cancer cell proliferation.
Vasquez, Judy L; Lai,Yanhao; Annamalai,Thirunavukkarasu;Jiang, Zhongliang;Zhang, Manqi; Lei ...
R01ES023569 Biochimie (2020 Jan) 31756402
2020
Inhibition of Excision of Oxidatively GeneratedHydantoin DNA Lesions by NEIL1 by the CompetitiveBi ...
Kolbanovskiy, Marina;Shim, Yoonjung; Min,Jung-Hyun; Geacintov,Nicholas E; Shafirovich,Vladi ...
R01ES027059 Biochemistry (2020 05 12) 32302101
2020
Insights into dental mineralization from three heritablemineralization disorders.
Chavez, Michael B;Kramer, Kaitrin; Chu,Emily Y;Thumbigere-Math,Vivek; Foster, Brian L
R24ES028531 J Struct Biol (2020 Oct 01) 32758526
2020
Insights into the Direct Oxidative Repair of EthenoLesions: MD and QM/MM Study on the Substrate Sco...
Lenz, Stefan A P; Li,Deyu; Wetmore, StaceyD
R01ES028865,R01ES028865
DNA Repair (Amst) (202012)
33161373
2020
Integrative QTL analysis of gene expression andchromatin accessibility identifies multi-tissue patt ...
Keele, Gregory R;Quach, Bryan C; Israel,Jennifer W; Chappell,Grace A; Lewis,Lauren; Safi, ...
P30ES010126,P30ES025128,R01ES029911
PLoS Genet (2020 01) 31961859
2020
Intergenerational transmission of childhood trauma?Testing cellular aging in mothers exposed to sex ...
Etzel, Laura; Hastings,Waylon J; Mattern,Brooke C; Oxford,Monica L; Heim,Christine; Putnam, ...
U01ES030949 Psychoneuroendocrinology(2020 10)
32629221
2020
Keratinocyte autophagy enables the activation ofkeratinocytes and fibroblasts and facilitates wound ...
Qiang, Lei; Yang,Seungwon; Cui,Yan-Hong; He,Yu-Ying
R01ES024373,R01ES030576,R01ES031534
Autophagy (2020 Sep 18) 32866426
2020
Long non-coding RNA Gm15441 attenuates hepaticinflammasome activation in response to PPARAagonism ...
Brocker, Chad N; Kim,Donghwan; Melia,Tisha; Karri, Kritika;Velenosi, Thomas J;Takahashi, S ...
R01ES024421 Nat Commun (2020 11 17) 33203882
2020
Low-Dose Silver Nanoparticle Surface Chemistry andTemporal Effects on Gene Expression in Human Live...
House, John S; Bouzos,Evangelia; Fahy, KiraM; Francisco, VictorinoMiguel; Lloyd, DillonT; W ...
P42ES027704,R01ES029911,R15ES025929,R15ES025929
Small (2020 May) 32227433
2020
Macronutrient, Energy, and Bile Acid MetabolismPathways Altered Following a Physiological MealChal ...
Yu, Elaine A; Yu,Tianwei; Jones, Dean P;Martorell, Reynaldo;Ramirez-Zea, Manuel;Stein, Ary ...
P30ES019776,R01ES023485,U2CES030163
J Nutr (2020 08 01) 32597983
2020
Maternal cadmium exposure and neurobehavior inchildren: The HOME study.
Yang, Weili; Vuong,Ann M; Xie,Changchun; Dietrich,Kim N; Karagas,Margaret R; Lanphear,Bru ...
P30ES006096,P30ES013508,R01ES025214
Environ Res (2020 07) 32668545
2020
Maternal serum perfluoroalkyl substance mixtures andthyroid hormone concentrations in maternal and ...
Lebeaux, Rebecca M;Doherty, Brett T;Gallagher, Lisa G;Zoeller, R Thomas;Hoofnagle, Andrew N...
P01ES022832,P30ES013508,R01ES025214
Environ Res (2020 06) 32222633
2020
Maternal, cord, and three-year-old child serum thyroidhormone concentrations in the Health Outcomes ...
Doherty, Brett T;Kosarek, Noelle;Hoofnagle, Andy N; Xu,Yingying; Zoeller, RThomas; Yolton, ...
R01ES025214 Clin Endocrinol (Oxf)(2020 04)
31901217
2020
MCM8IP activates the MCM8-9 helicase to promoteDNA synthesis and homologous recombination uponDNA ...
Huang, Jen-Wei;Acharya, Ananya;Taglialatela, Angelo;Nambiar, Tarun S;Cuella-Martin, Raquel;...
R01ES030335 Nat Commun (2020 06 11) 32528060
2020
Merits and Limitations of Studying NeuronalDepolarization-Dependent Processes Using ElevatedExtern ...
Rienecker, Kira D A;Poston, Robert G; Saha,Ramendra N
R01ES028738 ASN Neuro (2020Jan-Dec)
33256465
2020
Mesenchymal Stem Cells as a Bio Organ forTreatment of Female Infertility.
Esfandyari, Sahar;Chugh, Rishi Man;Park, Hang-Soo;Hobeika, Elie; Ulin,Mara; Al-Hendy, Ayma...
R01ES028615 Cells (2020 10 08) 33050021
2020
Metabolic effects of air pollution exposure andreversibility.
Rajagopalan, Sanjay;Park, Bongsoo;Palanivel, Rengasamy;Vinayachandran,Vinesh; Deiuliis, Jef ...
R01ES015146,R01ES015146,R01ES019616,U01ES026721
J Clin Invest (2020 Nov02)
32780721
2020
Metabolomic Profiling After a Meal Shows GreaterChanges and Lower Metabolic Flexibility in Cardiome...
Yu, Elaine A; Yu,Tianwei; Jones, Dean P;Ramirez-Zea, Manuel;Stein, Aryeh D
P30ES019776,R01ES023485,U2CES030163
J Endocr Soc (2020 Nov01)
33134764
2020
Methodologies for detecting environmentally inducedDNA damage and repair.
Li, Wentao; Sancar,Aziz
R01ES027255 Environ Mol Mutagen(2020 08)
32083352
2020
Mini-review: Epigenetic mechanisms that promotetransgenerational actions of endocrine disrupting ch ...
Martini, Mariangela;Corces, Victor G;Rissman, Emilie F
R01ES027859,R01ES027859
Horm Behav (2020 03) 31927019
2020
Mismatch repair and DNA polymerase δ proofreadingprevent catastrophic accumulation of leading stran ...
Bulock, Chelsea R;Xing, Xuanxuan;Shcherbakova, Polina V
R01ES015869 Nucleic Acids Res (202009 18)
32756902
2020
Mitochondria and aging in older individuals: ananalysis of DNA methylation age metrics, leukocyte t...
Dolcini, Jacopo; Wu,Haotian;Nwanaji-Enwerem,Jamaji C;Kiomourtozlogu,Marianthi-Anna; Cayir,...
P30ES009089,R01ES025225,R01ES027747
Aging (Albany NY) (202002 02)
32009007
2020
Mitochondrial dysfunction and DNA damageaccompany enhanced levels of formaldehyde incultured prima ...
Nadalutti, Cristina A;Stefanick, Donna F;Zhao, Ming-Lang;Horton, Julie K; Prasad,Rajendra; ...
R01ES031635,R56ES013773
Sci Rep (2020 03 27) 32221313
2020
Molecular and structural characterization ofdisease-associated APE1 polymorphisms.
Whitaker, Amy M;Stark, Wesley J; Flynn,Tony S; Freudenthal,Bret D
R01ES029203 DNA Repair (Amst) (2020Jul - Aug)
32454397
2020
Molecular Bio-Imaging Probe for Non-InvasiveDifferentiation Between Human Leiomyoma VersusLeiomyos ...
Shalaby, Shahinaz;Khater, Mostafa;Laknaur, Archana;Arbab, Ali; Al-Hendy,Ayman
R01ES028615 Reprod Sci (2020 02) 31925772
2020
Molecular Mechanisms of Arsenic-Induced Disruptionof DNA Repair.
Tam, Lok Ming; Price,Nathan E; Wang,Yinsheng
R01ES029749,T32ES018827
Chem Res Toxicol (202003 16)
31986875
2020
Monogenic and polygenic inheritance becomeinstruments for clonal selection.
Loh, Po-Ru; Genovese,Giulio; McCarroll,Steven A
DP2ES030554 Nature (2020 08) 32581363
2020
Mouse Genetic Reference Populations: CellularPlatforms for Integrative Systems Genetics.
Swanzey, Emily;O'Connor, Callan;Reinholdt, Laura G
R01ES029916 Trends Genet (2020 Sep30)
33010949
2020
MTOR-initiated metabolic switch and degeneration inthe retinal pigment epithelium.
Go, Young-Mi; Zhang,Jing; Fernandes, Jolyn;Litwin, Christopher;Chen, Rui; Wensel,Theodore ...
R01ES023485 FASEB J (2020 Sep) 32721041
2020
Mutagenesis mechanism of the major oxidativeadenine lesion 7,8-dihydro-8-oxoadenine.
Koag, Myong-Chul;Jung, Hunmin; Lee,Seongmin
R01ES026676 Nucleic Acids Res (202005 21)
32282906
2020
MYC Regulation of D2HGDH and L2HGDHInfluences the Epigenome and Epitranscriptome.
Qiu, ZhiJun; Lin,An-Ping; Jiang, Shoulei;Elkashef, Sara M;Myers, Jamie;Srikantan, Subraman ...
R01ES031522 Cell Chem Biol (2020 0521)
32101699
2020
N6-methyladenosine mediates arsenite-induced humankeratinocyte transformation by suppressing p53 ac ...
Zhao, Tianhe; Sun,Donglei; Zhao, Manyu;Lai, Yanhao; Liu, Yuan;Zhang, Zunzhen
R01ES023569 Environ Pollut (2020 Apr) 31931413
2020
NAD+-mediated regulation of mammalian baseexcision repair.
Saville, Kate M; Clark,Jennifer; Wilk, Anna;Rogers, Gresyn D;Andrews, Joel F;Koczor, Chris ...
P01ES028949,R01ES014811,U01ES029518,U01ES029518
DNA Repair (Amst) (202009)
33087267
2020
Natural variation in the sequestosome-related gene,sqst-5, underlies zinc homeostasis in Caenorhabd ...
Evans, Kathryn S;Zdraljevic, Stefan;Stevens, Lewis; Collins,Kimberly; Tanny,Robyn E; Anders ...
R01ES029930 PLoS Genet (2020 11) 33175833
2020
New insights into abasic site repair and tolerance. Thompson, Petria S;Cortez, David
R01ES030575 DNA Repair (Amst) (202006)
32417669
2020
New insights into the regulation of DNA-ProteinCrosslink Repair by the Aspartic Protease Ddi1 in ye...
El Dika, Mohammed R01ES030575 DNA Repair (Amst) (202006)
32330640
2020
Non-hormonal mediators of uterine fibroid growth. Cetin, Esra; Al-Hendy,Ayman; Ciebiera,Michał
R01ES028615 Curr Opin Obstet Gynecol(2020 10)
32739973
2020
Nonsteroidal Antiinflammatory Drugs Modify theEffect of Short-Term Air Pollution on Lung Function.
Gao, Xu; Coull, Brent;Lin, Xihong; Vokonas,Pantel; Schwartz, Joel;Baccarelli, Andrea A
P30ES009089,R01ES025225,R01ES027747
Am J Respir Crit CareMed (2020 02 01)
31553629
2020
NUCKS1 promotes RAD54 activity in homologousrecombination DNA repair.
Maranon, David G;Sharma, Neelam;Huang, Yuxin;Selemenakis, Platon;Wang, Meiling; Altina,No ...
R03ES029206 J Cell Biol (2020 Oct 05) 32876692
2020
Nuclear and Cytoplasmic Functions of Vitamin C. Zhitkovich, Anatoly R01ES008786,R01ES028072,R01ES031002
Chem Res Toxicol (2020Oct 19)
33001635
2020
Olanzapine-induced liver injury in mice: aggravationby high-fat diet and protection with sulforapha ...
Isaacson, Robin H;Beier, Juliane I; Khoo,Nicholas Kh; Freeman,Bruce A; Freyberg,Zachary; Ar ...
R21ES031531,T32ES011564
J Nutr Biochem (2020 07) 32388251
2020
Omics Integration for Mitochondria Systems Biology.
Hu, Xin; Go,Young-Mi; Jones, DeanP
P30ES019776,R01ES023485,U2CES030163
Antioxid Redox Signal(2020 04 20)
31891667
2020
Oncometabolites suppress DNA repair by disruptinglocal chromatin signalling.
Sulkowski, Parker L;Oeck, Sebastian; Dow,Jonathan; Economos,Nicholas G;Mirfakhraie, Lily; L ...
R01ES005775 Nature (2020 06) 32494005
2020
Organoarsenicals inhibit bacterial peptidoglycanbiosynthesis by targeting the essential enzyme MurA ...
Garbinski, Luis D;Rosen, Barry P;Yoshinaga, Masafumi
R01ES023779 Chemosphere (2020 Sep) 32957300
2020
Oxidative DNA Damage Modulates DNA MethylationPattern in Human Breast Cancer 1 (BRCA1) Gene viathe ...
Jiang, Zhongliang; Lai,Yanhao; Beaver, Jill M;Tsegay, Pawlos S;Zhao, Ming-Lang;Horton, Jul ...
R01ES023569 Cells (2020 01 16) 31963223
2020
Pathogenic Mechanisms of Somatic Mutation andGenome Mosaicism in Aging.
Vijg, Jan; Dong, Xiao U01ES029519 Cell (2020 Jul 09) 32649873
2020
Pharmacological methods to transcriptionallymodulate double-strand break DNA repair.
Kaplan, Alanna R;Glazer, Peter M
R01ES005775 Int Rev Cell Mol Biol(2020)
32475473
2020
Plasma acylcarnitine levels increase with healthyaging.
Jarrell, Zachery R;Smith, M Ryan; Hu,Xin; Orr, Michael; Liu,Ken H; Quyyumi,Arshed A; Jones ...
R01ES023485 Aging (Albany NY) (202006 16)
32554854
2020
Pol β gap filling, DNA ligation and substrate-productchanneling during base excision repair opposit ...
Çağlayan, Melike R00ES026191 DNA Repair (Amst) (202011)
32853828
2020
Pol μ ribonucleotide insertion opposite 8-oxodGfacilitates the ligation of premutagenic DNA repair ...
Çağlayan, Melike R00ES026191 Sci Rep (2020 01 22) 31969622
2020
POLE Mutation Spectra Are Shaped by the MutantAllele Identity, Its Abundance, and Mismatch Repair S...
Hodel, Karl P; Sun,Meijuan J S;Ungerleider, Nathan;Park, Vivian S;Williams, Leonard G;Baue ...
R01ES028271 Mol Cell (2020 06 18) 32497495
2020
Polybrominated diphenyl ether (PBDE) and poly- andperfluoroalkyl substance (PFAS) exposures during ...
Vuong, Ann M; Yolton,Kimberly; Braun,Joseph M; Sjodin,Andreas; Calafat,Antonia M; Xu, Ying ...
P30ES006096,P30ES013508,R01ES025214,T32ES010957
Environ Int (2020 06) 32259757
2020
Polycystic Ovary Syndrome: A Brain DisorderCharacterized by Eating Problems Originating duringPube ...
Steegers-Theunissen,Régine P M; Wiegel,Rosalieke E; Jansen,Pauline W; Laven, JoopS E; Sincla ...
R01ES030374,R01ES030374
Int J Mol Sci (2020 Nov03)
33153014
2020
Prenatal exposure to a mixture of persistent organicpollutants (POPs) and child reading skills at s ...
Vuong, Ann M; Xie,Changchun; Jandarov,Roman; Dietrich, KimN; Zhang, Hongmei;Sjödin, Andrea ...
P30ES006096,R01ES025214,T32ES010957
Int J Hyg Environ Health(2020 07)
32521479
2020
Promutagenic bypass of 7,8-dihydro-8-oxoadenine bytranslesion synthesis DNA polymerase Dpo4.
Jung, Hunmin; Lee,Seongmin
R01ES026676 Biochem J (2020 Aug 14) 32686822
2020
Protection from DNA re-methylation by transcriptionfactors in primordial germ cells and pre-implant ...
Kremsky, Isaac; Corces,Victor G
R01ES027859,R01ES027859
Genome Biol (2020 05 18) 32423419
2020
Proteome-wide Interrogation of Small GTPasesRegulated by N6-Methyladenosine Modulators.
Yang, Yen-Yu; Yu,Kailin; Li, Lin; Huang,Ming; Wang, Yinsheng
R35ES031707,T32ES018827
Anal Chem (2020 07 21) 32567849
2020
Quantification of the pace of biological aging inhumans through a blood test, the DunedinPoAm DNAm ...
Belsky, Daniel W;Caspi, Avshalom;Arseneault, Louise;Baccarelli, Andrea;Corcoran, David L; G ...
P30ES009089,R01ES025225,R01ES027747
Elife (2020 05 05) 32367804
2020
RAD51 Gene Family Structure and Function. Bonilla, Braulio;Hengel, Sarah R;Grundy, McKenzie K;Bernstein, Kara A
R01ES030335 Annu Rev Genet (2020 1123)
32663049
2020
Rad54 and Rdh54 occupy spatially and functionallydistinct sites within the Rad51-ssDNA presynaptic ...
Crickard, J Brooks;Kwon, Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 EMBO J (2020 Oct 15) 32790929
2020
Rad54 Drives ATP Hydrolysis-Dependent DNASequence Alignment during HomologousRecombination.
Crickard, J Brooks;Moevus, Corentin J;Kwon, Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 Cell (2020 06 11) 32502392
2020
Radiation Treatment, ATM, BRCA1/2, andCHEK2*1100delC Pathogenic Variants and Risk ofContralateral ...
Reiner, Anne S;Robson, Mark E;Mellemkjær, Lene;Tischkowitz, Marc;John, Esther M; Lynch,Ch ...
R01ES027121 J Natl Cancer Inst (2020Dec 14)
32119081
2020
Recognition of DNA adducts by edited and uneditedforms of DNA glycosylase NEIL1.
Minko, Irina G;Vartanian, Vladimir L;Tozaki, Naoto N;Coskun, Erdem;Coskun, Sanem Hosbas;Ja ...
R01ES031086 DNA Repair (Amst) (202001)
31733589
2020
Reduction of environmental pollutants for preventionof cardiovascular disease: it's time to act.
Münzel, Thomas;Miller, Mark R;Sørensen, Mette;Lelieveld, Jos; Daiber,Andreas; Rajagopalan,...
R01ES019616,U01ES026721
Eur Heart J (2020 Nov 01) 33141181
2020
Reference Standardization for Quantification andHarmonization of Large-Scale Metabolomics.
Liu, Ken H; Nellis,Mary; Uppal, Karan;Ma, Chunyu; Tran,ViLinh; Liang,Yongliang; Walker, D...
P30ES019776,R01ES023485,U2CES030163
Anal Chem (2020 07 07) 32490663
2020
Regenerating zebrafish fin epigenome is characterizedby stable lineage-specific DNA methylation and ...
Lee, Hyung Joo; Hou,Yiran; Chen, Yujie;Dailey, Zea Z;Riddihough, Aiyana;Jang, Hyo Sik; Wan ...
U24ES026699 Genome Biol (2020 02 27) 32106888
2020
Regulation and pharmacological targeting of RAD51in cancer.
Grundy, McKenzie K;Buckanovich, Ronald J;Bernstein, Kara A
R01ES030335 NAR Cancer (2020 Sep) 33015624
2020
Remarkable Enhancement of Nucleotide ExcisionRepair of a Bulky Guanine Lesion in a CovalentlyClose ...
Kolbanovskiy, Marina;Aharonoff, Abraham;Sales, Ana Helena;Geacintov, Nicholas E;Shafirovich, ...
R01ES027059 Biochemistry (2020 Aug11)
32786887
2020
Requisite Chromatin Remodeling for Myeloid andErythroid Lineage Differentiation fromErythromyeloid ...
Wu, Jun; Krchma,Karen; Lee, Hyung Joo;Prabhakar, Sairam;Wang, Xiaoli; Zhao,Haiyong; Xing, ...
U24ES026699 Cell Rep (2020 Nov 17) 33207205
2020
Research Participants' Attitudes towards ReceivingInformation on Genetic Susceptibility to Arsenic ...
Tamayo, Lizeth I; Lin,Hannah; Ahmed,Alauddin; Shahriar,Hasan; Hasan, Rabiul;Sarwar, Golam; ...
P30ES027792,P42ES010349,R24ES028532,R35ES028379
Public Health Genomics(2020)
32069464
2020
REV1 inhibitor JH-RE-06 enhances tumor cellresponse to chemotherapy by triggering senescencehallma ...
Chatterjee, Nimrat;Whitman, Matthew A;Harris, Cynthia A; Min,Sophia M; Jonas,Oliver; Lien, ...
P30ES002109,R35ES028303
Proc Natl Acad Sci U S A(2020 11 17)
33168727
2020
Rev7 loss alters cisplatin response and increases drugefficacy in chemotherapy-resistant lung cance ...
Vassel, Faye-Marie;Bian, Ke; Walker,Graham C; Hemann,Michael T
P30ES002109,R35ES028303,T32ES007020
Proc Natl Acad Sci U S A(2020 11 17)
33144509
2020
Ribonucleotide incorporation in yeast genomic DNAshows preference for cytosine and guanosine preced ...
Balachander, Sathya;Gombolay, Alli L;Yang, Taehwan; Xu,Penghao; Newnam,Gary; Keskin, Havva ...
R01ES026243 Nat Commun (2020 05 15) 32415081
2020
Robust principal component analysis for accurateoutlier sample detection in RNA-Seq data.
Chen, Xiaoying; Zhang,Bo; Wang, Ting; Bonni,Azad; Zhao, Guoyan
U24ES026699 BMC Bioinformatics (2020Jun 29)
32600248
2020
Role of Isocitrate Dehydrogenase 2 on DNAHydroxymethylation in Human Airway SmoothMuscle Cells.
Yeung, Bonnie H Y;Huang, Jessie; An,Steven S; Solway,Julian; Mitzner, Wayne;Tang, Wan-Yee
R01ES024784 Am J Respir Cell Mol Biol(2020 07)
32150688
2020
Role of Nucleotide Excision Repair in CisplatinResistance.
Duan, Mingrui;Ulibarri, Jenna; Liu, KeJian; Mao, Peng
R01ES030993,R21ES029302
Int J Mol Sci (2020 Dec04)
33291532
2020
Roles for MDC1 in cancer development and treatment.
Ruff, Sophie E; Logan,Susan K; Garabedian,Michael J; Huang, TonyT
R01ES025166 DNA Repair (Amst) (202011)
32866776
2020
Seasonally variant gene expression in full-term humanplacenta.
Clarkson-Townsend,Danielle A; Kennedy,Elizabeth; Everson,Todd M; Deyssenroth,Maya A; Burt, ...
P30ES019776,R01ES025145,R01ES025145,R24ES028507,T32ES012870
FASEB J (2020 Aug) 32574425
2020
Semisynthesis of the Organoarsenical AntibioticArsinothricin.
Suzol, Sazzad H; HasanHowlader, A; Galván,Adriana E;Radhakrishnan,Manohar; Wnuk,Stanislaw ...
R01ES023779 J Nat Prod (2020 09 25) 32830503
2020
Sex-dependent effects of preconception exposure toarsenite on gene transcription in parental germ c ...
Venkatratnam,Abhishek; Douillet,Christelle; Topping,Brent C; Shi, Qing;Addo, Kezia A; Idera ...
P42ES031007,R01ES028721,R01ES028721,R01ES029925
Arch Toxicol (2020 Nov03)
33145626
2020
Single-molecule live-cell imaging revealsRecB-dependent function of DNA polymerase IVin double str ...
Henrikus, Sarah S;Henry, Camille;McGrath, Amy E;Jergic, Slobodan;McDonald, John P;Hellmich ...
R35ES028343 Nucleic Acids Res (202009 04)
32687193
2020
Structural basis for STAT2 suppression by flavivirusNS5.
Wang, Boxiao;Thurmond, Stephanie;Zhou, Kang;Sánchez-Aparicio,Maria T; Fang, Jian; Lu,Jiuw ...
R35ES031707 Nat Struct Mol Biol (202010)
32778820
2020
Structural biology of DNA abasic site protection bySRAP proteins.
Amidon, Katherine M;Eichman, Brandt F
R01ES030575 DNA Repair (Amst) (202010)
32663791
2020
Structural insights into the promutagenic bypass of themajor cisplatin-induced DNA lesion.
Ouzon-Shubeita, Hala;Vilas, Caroline K; Lee,Seongmin
R01ES026676 Biochem J (2020 03 13) 32039434
2020
TCDD-induced multi- and transgenerational changes inthe methylome of male zebrafish gonads.
Akemann, Camille;Meyer, Danielle N;Gurdziel, Katherine;Baker, Tracie R
F31ES030278,F31ES030278,P30ES020957,R01ES030722,R01ES030722
Environ Epigenet (2020) 33214906
2020
Tethering-facilitated DNA 'opening' andcomplementary roles of β-hairpin motifs in theRad4/XPC DNA ...
Paul, Debamita; Mu,Hong; Tavakoli,Amirrasoul; Dai, Qing;Chen, Xuejing;Chakraborty, Sagnik; ...
R01ES025987 Nucleic Acids Res (202012 02)
33119737
2020
TGF-β Promotes Metabolic Reprogramming in LungFibroblasts via mTORC1-dependent ATF4 Activation.
O'Leary, Erin M; Tian,Yufeng; Nigdelioglu,Recep; Witt, Leah J;Cetin-Atalay, Rengul;Meliton, ...
U01ES026718 Am J Respir Cell Mol Biol(2020 11)
32668192
2020
The antitumorigenic roles of BRCA1-BARD1 in DNArepair and replication.
Tarsounas, Madalena;Sung, Patrick
R01ES007061 Nat Rev Mol Cell Biol(2020 05)
32094664
2020
The association between neuraxial anesthesia and thedevelopment of childhood asthma - a secondary a ...
Huang, Yueyang;Tzeng, Jung-Ying;Maguire, Rachel; Hoyo,Cathrine; Allen,Terrence
P30ES025128,R24ES028531
Curr Med Res Opin (202006)
32212939
2020
The cadmium-responsive gene, cdr-6, does notinfluence Caenorhabditis elegans responses toexogenous ...
Evans, Kathryn S;Andersen, Erik C
R01ES029930 MicroPubl Biol (2020 Sep14)
33005884
2020
The conserved DNMT1-dependent methylationregions in human cells are vulnerable to neurotoxicantrot ...
Freeman, Dana M; Lou,Dan; Li, Yanqiang;Martos, Suzanne N;Wang, Zhibin
R01ES025761,R01ES025761,U01ES026721
Epigenetics Chromatin(2020 03 16)
32178731
2020
The DNA-binding activity of USP1-associated factor 1is required for efficient RAD51-mediated homolo ...
Liang, Fengshan;Miller, Adam S; Tang,Caroline; Maranon,David; Williamson,Elizabeth A; Hroma ...
R01ES007061 J Biol Chem (2020 06 12) 32350107
2020
The Evolution of Variance Control. Bruijning, Marjolein;Metcalf, C Jessica E;Jongejans, Eelke;Ayroles, Julien F
R01ES029929 Trends Ecol Evol (202001)
31519463
2020
The Gene scb-1 Underlies Variation in Caenorhabditiselegans Chemotherapeutic Responses.
Evans, Kathryn S;Andersen, Erik C
R01ES029930 G3 (Bethesda) (2020 0707)
32385045
2020
The Great Oxidation Event expanded the geneticrepertoire of arsenic metabolism and cycling.
Chen, Song-Can; Sun,Guo-Xin; Yan, Yu;Konstantinidis,Konstantinos T; Zhang,Si-Yu; Deng, Ye; ...
R01ES023779 Proc Natl Acad Sci U S A(2020 05 12)
32350143
2020
The involvement of nucleotide excision repair proteinsin the removal of oxidative DNA damage.
Kumar, Namrata; Raja,Sripriya; Van Houten,Bennett
R35ES031638 Nucleic Acids Res (202011 18)
33010169
2020
The ligation of pol β mismatch insertion productsgoverns the formation of promutagenic base excisio ...
Çağlayan, Melike R00ES026191 Nucleic Acids Res (202004 17)
32140717
2020
The multifaceted role of PARP1 in RNA biogenesis. Eleazer, Rebekah;Fondufe-Mittendorf,Yvonne N
R01ES024478 Wiley Interdiscip RevRNA (2020 Jul 12)
32656996
2020
The Pseudomonas putida NfnB nitroreductase confersresistance to roxarsone.
Chen, Jian; Rosen,Barry P
R01ES023779 Sci Total Environ (2020Dec 15)
32810805
2020
The qBED track: a novel genome browservisualization for point processes.
Moudgil, Arnav; Li,Daofeng; Hsu, Silas;Purushotham, Deepak;Wang, Ting; Mitra,Robi D
U24ES026699 Bioinformatics (2020 Sep17)
32941613
2020
The role of endocrine-disrupting chemicals in uterinefibroid pathogenesis.
Bariani, Maria Victoria;Rangaswamy, Roshni;Siblini, Hiba; Yang,Qiwei; Al-Hendy,Ayman; Zota, ...
R01ES028615 Curr Opin EndocrinolDiabetes Obes (2020 12)
33044243
2020
The role of environmental exposures and theepigenome in health and disease.
Perera, Bambarendage PU; Faulk, Christopher;Svoboda, Laurie K;Goodrich, Jaclyn M;Dolinoy, D ...
P30ES017885,T32ES007062,U01ES026697
Environ Mol Mutagen(2020 01)
31177562
2020
The Role of Hedgehog Pathway in Female Cancers. Garcia, Natalia; Ulin,Mara; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 J Cancer Sci Clin Ther(2020)
33179013
2020
The roles of polymerases ν and θ in replicative bypassof O6- and N2-alkyl-2'-deoxyguanosine lesions ...
Du, Hua; Wang,Pengcheng; Wu, Jun;He, Xiaomei; Wang,Yinsheng
R01ES029749 J Biol Chem (2020 04 03) 32098870
2020
The Selective Progesterone Receptor ModulatorUlipristal Acetate Inhibits the Activity of the Glucoc ...
Small, Benjamin;Millard, Charles E F;Kisanga, Edwina P;Burman, Andreanna;Anam, Anika; Flann ...
R01ES028615 J Clin Endocrinol Metab(2020 03 01)
31665442
2020
Tissue-Resident Alveolar Macrophages Do Not Relyon Glycolysis for LPS-induced Inflammation.
Woods, Parker S;Kimmig, Lucas M;Meliton, Angelo Y;Sun, Kaitlyn A; Tian,Yufeng; O'Leary, Er ...
P30ES027792,R01ES015024,U01ES026718
Am J Respir Cell Mol Biol(2020 02)
31469581
2020
Tissue-specific usage of transposable element-derivedpromoters in mouse development.
Miao, Benpeng; Fu,Shuhua; Lyu, Cheng;Gontarz, Paul; Wang,Ting; Zhang, Bo
U24ES026699 Genome Biol (2020 09 28) 32988383
2020
TM3'seq: A Tagmentation-Mediated 3' SequencingApproach for Improving Scalability of RNAseqExperime ...
Pallares, Luisa F;Picard, Serge; Ayroles,Julien F
R01ES029929 G3 (Bethesda) (2020 0107)
31676507
2020
ToxPoint: Dissecting Functional RNA Modificationsin Responses to Environmental Exposure-Mechanistic...
Yang, Chengfeng R01ES026151,R01ES029942
Toxicol Sci (2020 03 01) 32101319
2020
Translesion synthesis of 6-nitrochrysene-derived2'-deoxyadenosine adduct in human cells.
Powell, Brent V;Bacurio, Jan Henric T;Basu, Ashis K
R01ES023350 DNA Repair (Amst) (202011)
32721818
2020
Translesion synthesis of the major nitrogenmustard-induced DNA lesion by human DNApolymerase η.
Jung, Hunmin; Rayala,Naveen Kumar; Lee,Seongmin
R01ES026676 Biochem J (2020 12 11) 33175093
2020
Trinucleotide repeat instability via DNA base excisionrepair.
Lai, Yanhao; Beaver,Jill M; Laverde,Eduardo; Liu, Yuan
R01ES023569 DNA Repair (Amst) (202009)
33087278
2020
Tumor-Targeted, Cytoplasmic Delivery of Large,Polar Molecules Using a pH-Low Insertion Peptide.
Svoronos, Alexander A;Bahal, Raman; Pereira,Mohan C; Barrera,Francisco N; Deacon,John C; Bo ...
R01ES005775 Mol Pharm (2020 02 03) 31855437
2020
Twenty years of t-loops: A case study for theimportance of collaboration in molecular biology.
Tomáška, Ľubomír;Cesare, Anthony J;AlTurki, Taghreed M;Griffith, Jack D
R01ES031635 DNA Repair (Amst) (2020Oct)
32620538
2020
Ubiquitinated-PCNA protects replication forks fromDNA2-mediated degradation by regulating Okazaki f...
Thakar, Tanay; Leung,Wendy; Nicolae,Claudia M; Clements,Kristen E; Shen,Binghui; Bielinsky, ...
R01ES026184 Nat Commun (2020 05 01) 32358495
2020
Unhooking of an interstrand cross-link at DNA forkstructures by the DNA glycosylase NEIL3.
Imani Nejad, Maryam;Housh, Kurt;Rodriguez, Alyssa A;Haldar, Tuhin; Kathe,Scott; Wallace, S ...
R01ES021007 DNA Repair (Amst) (202002)
31923807
2020
Using Genetic and Species Diversity to Tackle KidneyDisease.
Garrett, Michael R;Korstanje, Ron
R01ES029916 Trends Genet (2020 07) 32362446
2020
USP7-mediated deubiquitination differentiallyregulates CSB but not UVSSA upon UVradiation-induced ...
Zhu, Qianzheng; Ding,Nan; Wei, Shengcai; Li,Ping; Wani, Gulzar; He,Jinshan; Wani, Altaf A
R01ES012991 Cell Cycle (2020 01) 31775559
2020
Uterine fibroids in menopause and perimenopause. Ulin, Mara; Ali,Mohamed; Chaudhry,Zunir Tayyeb;Al-Hendy, Ayman;Yang, Qiwei
R01ES028615 Menopause (2020 02) 31834160
2020
Variable impact of conformationally distinct DNAlesions on nucleosome structure and dynamics: Impli...
Cai, Yuqin; Geacintov,Nicholas E; Broyde,Suse
R01ES025987 DNA Repair (Amst) (202003)
32018112
2020
Vinyl Chloride and High-Fat Diet as a Model ofEnvironment and Obesity Interaction.
Lang, Anna L;Goldsmith, William T;Schnegelberger, ReginaD; Arteel, Gavin E;Beier, Juliane I
R21ES031531 J Vis Exp (2020 01 12) 31984951
2020
Vitamin D and uterine fibroids: preclinical evidence isin; time for an overdue clinical study!
Ali, Mohamed; Prince,Lillian; Al-Hendy,Ayman
R01ES028615 Fertil Steril (2020 01) 32033736
2020
What Is Lost in the Weismann Barrier? Bline, Abigail P; LeGoff, Anne; Allard,Patrick
R01ES027487,R01ES027487
J Dev Biol (2020 Dec 16) 33339122
2020
YTHDF2 Binds to 5-Methylcytosine in RNA andModulates the Maturation of Ribosomal RNA.
Dai, Xiaoxia; Gonzalez,Gwendolyn; Li, Lin; Li,Jie; You, Changjun;Miao, Weili; Hu,Junchi; ...
R01ES025121,T32ES018827
Anal Chem (2020 01 07) 31815440
2020
YY1 interacts with guanine quadruplexes to regulateDNA looping and gene expression.
Li, Lin; Williams,Preston; Ren, Wendan;Wang, Michelle Y; Gao,Zi; Miao, Weili; Huang,Ming; ...
R35ES031707,T32ES018827
Nat Chem Biol (2020 Nov16)
33199912
2020
1,25 Dihydroxyvitamin D3 Enhances the AntifibroidEffects of Ulipristal Acetate in Human Uterine Fib ...
Ali, Mohamed; Shahin,Sara Mahmoud; Sabri,Nagwa Ali; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 Reprod Sci (2019 06) 30514160
2019
1HN, 13C, and 15N backbone resonance assignmentsof the human DNA ligase 3 DNA-binding domain(resid ...
Roth, Braden M;Varney, Kristen M;Yang, Hui; Weber,David J; Tomkinson,Alan E
R01ES012512 Biomol NMR Assign(2019 10)
31093909
2019
1HN, 13C, and 15N resonance assignments of humancalmodulin bound to a peptide derived from the STRA...
Varney, Kristen M;Wilder, Paul T;Godoy-Ruiz, Raquel;Mancia, Filippo; Weber,David J
R01ES012512 Biomol NMR Assign(2019 10)
30875027
2019
5',8-Cyclopurine Lesions in DNA Damage: Chemical,Analytical, Biological, and Diagnostic Significanc ...
Chatgilialoglu,Chryssostomos; Ferreri,Carla; Geacintov,Nicholas E; Krokidis,Marios G; Liu, ...
R01ES023569,R01ES027059
Cells (2019 05 28) 31141888
2019
5-Formylcytosine-induced DNA-peptide cross-linksreduce transcription efficiency, but do not cause t ...
Ji, Shaofei; Park,Daeyoon; Kropachev,Konstantin;Kolbanovskiy, Marina;Fu, Iwen; Broyde, Sus...
R01ES023350,R01ES025987
J Biol Chem (2019 11 29) 31597704
2019
A missense variant in FTCD is associated with arsenicmetabolism and toxicity phenotypes in Banglade ...
Pierce, Brandon L;Tong, Lin; Dean,Samantha; Argos,Maria; Jasmine,Farzana;Rakibuz-Zaman, M ...
P30ES009089,P30ES027792,P42ES010349,R24ES028532,R35ES028379
PLoS Genet (2019 03) 30893314
2019
A non-randomized procedure for large-scaleheterogeneous multiple discrete testing based onrandomiz ...
Dai, Xiaoyu; Lin, Nan;Li, Daofeng; Wang,Ting
U24ES026699 Biometrics (2019 06) 30387496
2019
A Novel Gene Underlies Bleomycin-ResponseVariation in Caenorhabditis elegans.
Brady, Shannon C;Zdraljevic, Stefan;Bisaga, Karol W;Tanny, Robyn E; Cook,Daniel E; Lee, Da ...
R01ES029930 Genetics (2019 08) 31171655
2019
A parametric meta-analysis. Yu, Chang; Zelterman,Daniel
R01ES005775 Stat Med (2019 09 20) 31206759
2019
A Preliminary Study: Human Fibroid Stro-1+/CD44+Stem Cells Isolated From Uterine Fibroids Demonstra...
Prusinski Fernung,Lauren E; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 Reprod Sci (2019 05) 29954254
2019
A recurrent cancer-associated substitution in DNApolymerase ε produces a hyperactive enzyme.
Xing, Xuanxuan; Kane,Daniel P; Bulock,Chelsea R; Moore,Elizabeth A; Sharma,Sushma; Chabes, ...
R01ES015869 Nat Commun (2019 01 22) 30670691
2019
A Small Molecule Targeting Mutagenic TranslesionSynthesis Improves Chemotherapy.
Wojtaszek, Jessica L;Chatterjee, Nimrat;Najeeb, Javaria; Ramos,Azucena; Lee, Minhee;Bian, ...
R01ES028865,R01ES028865,R35ES028303
Cell (2019 06 27) 31178121
2019
A two-stage phase II clinical trial design with nestedcriteria for early stopping and efficacy.
DeVeaux, Michelle;Kane, Michael; Wei,Wei; Zelterman, Daniel
R01ES005775,R01ES019179
Pharm Stat (2019 11) 31507079
2019
A White-Box Machine Learning Approach forRevealing Antibiotic Mechanisms of Action.
Yang, Jason H; Wright,Sarah N; Hamblin,Meagan; McCloskey,Douglas; Alcantar,Miguel A; Schrüb ...
R35ES028303 Cell (2019 05 30) 31080069
2019
Aberrant Activation of β-Catenin Signaling DrivesGlioma Tumorigenesis via USP1-Mediated Stabilizati...
Ma, Li; Lin, Kangyu;Chang, Guoqiang;Chen, Yiwen; Yue,Chen; Guo, Qing;Zhang, Sicong; Jia, ...
R01ES025166 Cancer Res (2019 01 01) 30425057
2019
Accelerating cancer without mutations. Brash, Douglas E R01ES030562 Elife (2019 03 21) 30895924
2019 Accurate ethnicity prediction from placental DNAmethylation data.
Yuan, Victor; Price, EMagda; Del Gobbo,Giulia; Mostafavi, Sara;Cox, Brian; Binder,Alexandr ...
R01ES025145,R01ES025145,R24ES028507
Epigenetics Chromatin(2019 08 09)
31399127
2019
Acute effects of air pollution on mortality: A 17-yearanalysis in Kuwait.
Achilleos, Souzana;Al-Ozairi, Ebaa;Alahmad, Barrak;Garshick, Eric;Neophytou, Andreas M;Bou ...
R00ES027511 Environ Int (2019 05) 30844583
2019
Addendum: Ribose-seq: global mapping ofribonucleotides embedded in genomic DNA.
Koh, Kyung Duk;Balachander, Sathya;Hesselberth, Jay R;Storici, Francesca
R01ES026243 Nat Methods (2019 08) 31324896
2019
Aflatoxin-Guanine DNA Adducts and OxidativelyInduced DNA Damage in Aflatoxin-Treated Mice inVivo a ...
Coskun, Erdem; Jaruga,Pawel; Vartanian,Vladimir; Erdem, Onur;Egner, Patricia A;Groopman, J ...
R01ES031086 Chem Res Toxicol (201901 22)
30525498
2019
Aging-like Spontaneous Epigenetic SilencingFacilitates Wnt Activation, Stemness, andBrafV600E-Indu ...
Tao, Yong; Kang,Byunghak; Petkovich,Daniel A; Bhandari,Yuba R; In, Julie;Stein-O'Brien, Ge ...
R01ES011858 Cancer Cell (2019 02 11) 30753828
2019
AID-RNA polymerase II transcription-dependentdeamination of IgV DNA.
Pham, Phuong; Malik,Sohail; Mak, Chiho;Calabrese, Peter C;Roeder, Robert G;Goodman, Myron ...
R35ES028343 Nucleic Acids Res (201911 18)
31566237
2019
Air Pollution, Asthma, and Sleep Apnea: NewEpidemiological Links?
Mutlu, Gökhan M;Peker, Yüksel
P30ES027792,R01ES015024,U01ES026718
Ann Am Thorac Soc (2019Mar)
31339334
2019
Air pollution-derived particulate matter dysregulateshepatic Krebs cycle, glucose and lipid metabol ...
Reyes-Caballero,Hermes; Rao,Xiaoquan; Sun, Qiushi;Warmoes, Marc O; Lin,Penghui; Sussan, To ...
P30ES026529,U01ES026721
Sci Rep (2019 11 22) 31757983
2019
Arsinothricin, an arsenic-containing non-proteinogenicamino acid analog of glutamate, is a broad-sp ...
Nadar, VenkadeshSarkarai; Chen, Jian;Dheeman, DharmendraS; Galván, AdrianaEmilce; Yoshinaga- ...
R01ES023779 Commun Biol (2019 Apr15)
31925009
2019
Arsinothricin, an arsenic-containing non-proteinogenicamino acid analog of glutamate, is a broad-sp ...
Nadar, VenkadeshSarkarai; Chen, Jian;Dheeman, DharmendraS; Galván, AdrianaEmilce; Yoshinaga- ...
R01ES023779 Commun Biol (2019) 30993215
2019
Association between gestational urinary bisphenol aconcentrations and adiposity in young children: ...
Braun, Joseph M; Li,Nan; Arbuckle, Tye E;Dodds, Linda;Massarelli, Isabelle;Fraser, William ...
R01ES025214 Environ Res (2019 05) 30831435
2019
Association of a Pathway-Specific Genetic Risk ScoreWith Risk of Radiation-Associated Contralateral ...
Watt, Gordon P; Reiner,Anne S; Smith, SusanA; Stram, Daniel O;Capanu, Marinela;Malone, Kat ...
R01ES027121 JAMA Netw Open (201909 04)
31560388
2019
Association of Arsenic Exposure with Whole BloodDNA Methylation: An Epigenome-Wide Study ofBanglad ...
Demanelis, Kathryn;Argos, Maria; Tong,Lin; Shinkle, Justin;Sabarinathan, Mekala;Rakibuz-Zam ...
P30ES009089,P30ES027792,P42ES010349,R24ES028532,R35ES028379
Environ Health Perspect(2019 05)
31135185
2019
Associations of Benzo(ghi)perylene andHeptachlorodibenzo-p-dioxin in Serum of ServicePersonnel Dep ...
Smith, Matthew Ryan;Woeller, Collynn F;Uppal, Karan; Thatcher,Thomas H; Walker,Douglas I; H ...
P30ES019776,R01ES023485,U2CES030163
J Occup Environ Med(2019 12)
31800449
2019
Associations of cord blood leptin and adiponectin withchildren's cognitive abilities.
Li, Nan; Arbuckle, TyeE; Muckle, Gina;Lanphear, Bruce P;Boivin, Michel; Chen,Aimin; Dodds, ...
R01ES025214 Psychoneuroendocrinology(2019 01)
30390444
2019
Associations of serum perfluoroalkyl substance andvitamin D biomarker concentrations in NHANES, 200...
Etzel, Taylor M; Braun,Joseph M; Buckley,Jessie P
R01ES025214,T32ES007141
Int J Hyg Environ Health(2019 03)
30503928
2019
Benzo[a]pyrene Perturbs Mitochondrial and AminoAcid Metabolism in Lung Epithelial Cells and Has Sim...
Smith, Matthew Ryan;Walker, Douglas I;Uppal, Karan; Utell,Mark J; Hopke, PhilipK; Mallon, ...
P30ES019776,R01ES023485
J Occup Environ Med(2019 12)
31800453
2019
Bioactivation of the tobacco carcinogens4-aminobiphenyl (4-ABP) and2-amino-9H-pyrido[2,3-b]indole ...
Bellamri, Medjda; Yao,Lihua; Bonala, Radha;Johnson, Francis; VonWeymarn, Linda B;Turesky, ...
R01ES019564,R01ES030559
Arch Toxicol (2019 07) 31203411
2019
Biological Evaluation of DNA Biomarkers in aChemically Defined and Site-Specific Manner.
Bian, Ke; Delaney,James C; Zhou,Xianhao; Li, Deyu
R01ES028865,R01ES028865
Toxics (2019 Jun 25) 31242562
2019
Blood Leukocyte DNA Methylation Predicts Risk ofFuture Myocardial Infarction and Coronary Heart Dis...
Agha, Golareh;Mendelson, Michael M;Ward-Caviness, CavinK; Joehanes, Roby;Huan, TianXiao; Go ...
P30ES009089,R01ES025225,R01ES027747
Circulation (2019 08 20) 31424985
2019
BPA interferes with StAR-mediated mitochondrialcholesterol transport to induce germline dysfunction ...
Chen, Yichang; Panter,Blake; Hussain, Aleena;Gibbs, Katherine;Ferreira, Daniel; Allard,Pat ...
R01ES027487,R01ES027487,R25ES025507
Reprod Toxicol (2019 12) 31445225
2019
Burden of Uterine Fibroids: An African Perspective, ACall for Action and Opportunity for Interventi ...
Igboeli, P; Walker, W;McHugh, A; Sultan, A;Al-Hendy, A
R01ES028615 Curr Opin Gynecol Obstet(2019)
32647835
2019
Bypass of the Major Alkylative DNA Lesion byHuman DNA Polymerase η.
Koag, Myong-Chul;Jung, Hunmin; Kou, Yi;Lee, Seongmin
R01ES026676 Molecules (2019 Oct 31) 31683505
2019
Cadmium and High-Fat Diet Disrupt Renal, Cardiacand Hepatic Essential Metals.
Young, Jamie L; Yan,Xiaofang; Xu,Jianxiang; Yin, Xinmin;Zhang, Xiang; Arteel,Gavin E; Barn ...
R01ES027778,R01ES028102,T32ES011564
Sci Rep (2019 10 11) 31604971
2019
Cadmium exposure and MEG3 methylationdifferences between Whites and African Americans inthe NEST C ...
House, John S; Hall,Jonathan; Park, SarahS; Planchart, Antonio;Money, Eric; Maguire,Rachel ...
P42ES010356,R24ES028531
Environ Epigenet (2019Jul)
31528362
2019
Cadmium exposure upregulates SNAIL throughmiR-30 repression in human lung epithelial cells.
Tanwar, Vinay Singh;Zhang, Xiaoru;Jagannathan,Lakshmanan; Jose,Cynthia C; Cuddapah,Suresh
P30ES000260,R01ES024727
Toxicol Appl Pharmacol(2019 06 15)
30998937
2019
Capture of Ribonucleotides in Yeast Genomic DNAUsing Ribose-Seq.
Balachander, Sathya;Yang, Taehwan;Newnam, Gary;El-Sayed, Waleed M M;Koh, Kyung Duk;Storici ...
R01ES026243 Methods Mol Biol (2019) 31602603
2019
Cediranib suppresses homology-directed DNA repairthrough down-regulation of BRCA1/2 and RAD51.
Kaplan, Alanna R;Gueble, Susan E; Liu,Yanfeng; Oeck,Sebastian; Kim, Hoon;Yun, Zhong; Glaze ...
R01ES005775 Sci Transl Med (2019 0515)
31092693
2019
Characterization of rare NEIL1 variants found in EastAsian populations.
Minko, Irina G;Vartanian, Vladimir L;Tozaki, Naoto N; Linde,Oskar K; Jaruga, Pawel;Coskun, ...
R01ES029357 DNA Repair (Amst) (201907)
31100703
2019
Chronic Hexavalent Chromium Exposure InducesCancer Stem Cell-Like Property and Tumorigenesis byInc ...
Wang, Zhishan; Lin,Hsuan-Pei; Li, Yunfei;Tao, Hua; Yang, Ping;Xie, Jie; Maddy, Drew;Kondo ...
P30ES026529,R01ES028256,R01ES029496,R01ES029942
Toxicol Sci (2019 12 01) 31504995
2019
Comparative validation of an epigenetic mortality riskscore with three aging biomarkers for predict ...
Gao, Xu; Colicino,Elena; Shen, Jincheng;Just, Allan C;Nwanaji-Enwerem,Jamaji C; Wang, Cuic...
P30ES009089,R01ES025225,R01ES027747
Int J Epidemiol (2019 1201)
31038702
2019
Comparison of smoking-related DNA methylationbetween newborns from prenatal exposure and adultsfro ...
Sikdar, Sinjini;Joehanes, Roby;Joubert, Bonnie R; Xu,Cheng-Jian;Vives-Usano, Marta;Rezwan, ...
P42ES010356,R24ES028531,R24ES028533
Epigenomics (2019 10) 31536415
2019
Conformational regulation of Escherichia coli DNApolymerase V by RecA and ATP.
Jaszczur, MalgorzataM; Vo, Dan D;Stanciauskas, Ramunas;Bertram, Jeffrey G;Sikand, Adhirath; ...
R35ES028343 PLoS Genet (2019 02) 30716079
2019
Correlation over time of toenail metals amongparticipants in the VA normative aging study from1992 ...
Wu, Alexander C;Allen, Joseph G; Coull,Brent;Amarasiriwardena,Chitra; Sparrow, David;Vokon ...
P30ES000002,R01ES027747
J Expo Sci EnvironEpidemiol (2019 09)
30482937
2019
Coupling of PARP1-mediated chromatin structuralchanges to transcriptional RNA polymerase II elongat...
Matveeva, Elena A;Al-Tinawi, Qamar M H;Rouchka, Eric C;Fondufe-Mittendorf,Yvonne N
R01ES024478 Epigenetics Chromatin(2019 02 18)
30777121
2019
Current Research Approaches and Challenges in theObesogen Field.
Chamorro-Garcia,Raquel; Blumberg,Bruce
R01ES023316,R01ES023316
Front Endocrinol(Lausanne) (2019)
30967838
2019
Ddc2ATRIP promotes Mec1ATR activation atRPA-ssDNA tracts.
Biswas, Himadri; Goto,Greicy; Wang, Weibin;Sung, Patrick;Sugimoto, Katsunori
R01ES007061 PLoS Genet (2019 08) 31369547
2019
Defining the influence of Rad51 and Dmc1lineage-specific amino acids on genetic recombination.
Steinfeld, Justin B;Beláň, Ondrej; Kwon,Youngho; Terakawa,Tsuyoshi; Al-Zain,Amr; Smith, Mi ...
R01ES007061 Genes Dev (2019 09 01) 31371435
2019
Defining UHRF1 Domains that Support Maintenanceof Human Colon Cancer DNA Methylation andOncogenic ...
Kong, Xiangqian; Chen,Jie; Xie, Wenbing;Brown, Stephen M; Cai,Yi; Wu, Kaichun; Fan,Daimin ...
R01ES011858 Cancer Cell (2019 04 15) 30956060
2019
Determination of chemical-disease risk values toprioritize connections between environmental factor ...
Kosnik, Marissa B;Reif, David M
P30ES025128,R56ES030007,T32ES007046
Toxicol Appl Pharmacol(2019 09 15)
31323264
2019
Developmental origins of transgenerational spermDNA methylation epimutations following ancestralDD ...
Ben Maamar, Millissia;Nilsson, Eric;Sadler-Riggleman,Ingrid; Beck, Daniel;McCarrey, John R; ...
R01ES012974,R01ES012974
Dev Biol (2019 01 15) 30500333
2019
Diastereomeric Recognition of5',8-cyclo-2'-Deoxyadenosine Lesions by HumanPoly(ADP-ribose) Polymer ...
Masi, Annalisa; Sabbia,Arianna; Ferreri, Carla;Manoli, Francesco; Lai,Yanhao; Laverde, Edua...
R01ES023569 Cells (2019 02 02) 30717407
2019
Differential damage and repair of DNA-adductsinduced by anti-cancer drug cisplatin across mouse org...
Yimit, Askar; Adebali,Ogun; Sancar, Aziz;Jiang, Yuchao
P30ES010126,R01ES027255
Nat Commun (2019 01 18) 30659176
2019
Differential metabolism of inorganic arsenic in micefrom genetically diverse Collaborative Cross st ...
Stýblo, Miroslav;Douillet, Christelle;Bangma, Jacqueline;Eaves, Lauren A; deVillena, Fernan ...
R01ES028721,R01ES028721,R01ES029925
Arch Toxicol (2019 10) 31493028
2019
DNA methylation aging clocks: challenges andrecommendations.
Bell, Christopher G;Lowe, Robert; Adams,Peter D; Baccarelli,Andrea A; Beck,Stephan; Bell, ...
P30ES009089,R01ES014811,R01ES025225,R01ES027747
Genome Biol (2019 11 25) 31767039
2019
DNA methylome of human neonatal umbilical cord:Enrichment of differentially methylated regions comp...
Sakurai, Kenichi;Shioda, Keiko; Eguchi,Akifumi; Watanabe,Masahiro; Miyaso,Hidenori; Mori, ...
R01ES020454,R01ES020454,R01ES023316,R01ES023316
PLoS One (2019) 31063509
2019
DNA polymerase θ accomplishes translesion synthesisopposite 1,N6-ethenodeoxyadenosine with a remark ...
Yoon, Jung-Hoon;Johnson, Robert E;Prakash, Louise;Prakash, Satya
R01ES022948 Genes Dev (2019 03 01) 30808656
2019
DNA repair enzymes ALKBH2, ALKBH3, and AlkBoxidize 5-methylcytosine to 5-hydroxymethylcytosine,5-f ...
Bian, Ke; Lenz, StefanA P; Tang, Qi; Chen,Fangyi; Qi, Rui; Jost,Marco; Drennan,Catherine ...
P30ES002109,R01ES028865,R01ES028865
Nucleic Acids Res (201906 20)
31114894
2019
DNA replication studies of N-nitrosocompound-induced O6-alkyl-2'-deoxyguanosinelesions in Escheric ...
Wang, Pengcheng;Leng, Jiapeng; Wang,Yinsheng
R01ES025121 J Biol Chem (2019 03 15) 30655287
2019
DNA requirement in FANCD2 deubiquitination byUSP1-UAF1-RAD51AP1 in the Fanconi anemia DNAdamage re ...
Liang, Fengshan;Miller, Adam S;Longerich, Simonne;Tang, Caroline;Maranon, David;Williamson ...
R01ES007061 Nat Commun (2019 06 28) 31253762
2019
Drosophila, which lacks canonicaltranscription-coupled repair proteins, performstranscription-coup ...
Deger, Nazli; Yang,Yanyan; Lindsey-Boltz,Laura A; Sancar, Aziz;Selby, Christopher P
R01ES027255 J Biol Chem (2019 11 29) 31624146
2019
Dual regulation of Arabidopsis AGO2 by argininemethylation.
Hu, Po; Zhao, Hongwei;Zhu, Pei; Xiao,Yongsheng; Miao,Weili; Wang, Yinsheng;Jin, Hailing
R01ES025121 Nat Commun (2019 02 19) 30783097
2019
Dynamic interactions of the homologous pairing 2(Hop2)-meiotic nuclear divisions 1 (Mnd1) protein c...
Crickard, J Brooks;Kwon, Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 J Biol Chem (2019 01 11) 30420424
2019
Effects of Preconception and in Utero InorganicArsenic Exposure on the Metabolic Phenotype ofGenet ...
Fry, Rebecca C; Addo,Kezia A; Bell, TimothyA; Douillet, Christelle;Martin, Elizabeth;Stýblo ...
P30ES010126,R01ES029925
Chem Res Toxicol (201908 19)
31251040
2019
Environmental Cadmium Enhances Lung Injury byRespiratory Syncytial Virus Infection.
Hu, Xin; Kim, Ki-Hye;Lee, Youri; Fernandes,Jolyn; Smith, M Ryan;Jung, Yu-Jin; Orr,Michael ...
P30ES019776,R01ES023485
Am J Pathol (2019 08) 31108100
2019
Environmental Chemicals Altered in Association WithDeployment for High Risk Areas.
Smith, Matthew Ryan;Uppal, Karan; Walker,Douglas I; Utell, MarkJ; Hopke, Philip K;Mallon, ...
P30ES019776,R01ES023485
J Occup Environ Med(2019 12)
31800447
2019
Environmental Obesogens: Mechanisms andControversies.
Heindel, Jerrold J;Blumberg, Bruce
R01ES023316,R01ES023316
Annu Rev PharmacolToxicol (2019 01 06)
30044726
2019
Environmental Toxicant Induced EpigeneticTransgenerational Inheritance of Prostate Pathologyand St ...
Klukovich, Rachel;Nilsson, Eric;Sadler-Riggleman,Ingrid; Beck, Daniel;Xie, Yeming; Yan, We...
R01ES012974,R01ES012974
Sci Rep (2019 02 18) 30778168
2019
Epigenetic dysregulation of enhancers in neurons isassociated with Alzheimer's disease pathology an ...
Li, Peipei; Marshall,Lee; Oh, Gabriel;Jakubowski, Jennifer L;Groot, Daniel; He, Yu;Wang, ...
U24ES026699 Nat Commun (2019 05 21) 31113950
2019
Epigenetic Effects of Polybrominated Diphenyl Etherson Human Health.
Poston, Robert G; Saha,Ramendra N
R01ES028738 Int J Environ Res PublicHealth (2019 07 29)
31362383
2019
Epigenetic transgenerational inheritance of testispathology and Sertoli cell epimutations: generati ...
Sadler-Riggleman,Ingrid; Klukovich,Rachel; Nilsson, Eric;Beck, Daniel; Xie,Yeming; Yan, We ...
R01ES012974,R01ES012974
Environ Epigenet (2019Jul)
31528361
2019
Error-prone replication of a5-formylcytosine-mediated DNA-peptide cross-link inhuman cells.
Naldiga, Spandana; Ji,Shaofei; Thomforde,Jenna; Nicolae, ClaudiaM; Lee, Marietta;Zhang, Zh ...
R01ES023350,R01ES026184
J Biol Chem (2019 07 05) 31138652
2019
Error-Prone Replication through UV Lesions by DNAPolymerase θ Protects against Skin Cancers.
Yoon, Jung-Hoon;McArthur, Mark J;Park, Jeseong; Basu,Debashree; Wakamiya,Maki; Prakash, Lo ...
R01ES022948 Cell (2019 03 07) 30773314
2019
Estrogen down regulates COMT transcription viapromoter DNA methylation in human breast cancercells ...
Wu, Qian;Odwin-Dacosta, Shelly;Cao, Shuyuan; Yager,James D; Tang,Wan-Yee
R01ES024784 Toxicol Appl Pharmacol(2019 Mar 15)
30684530
2019
Evaluation of the Major Steps in the ConventionalProtocol for the Alkaline Comet Assay.
Karbaschi, Mahsa; Ji,Yunhee; Abdulwahed,Abdulhadi MohammedS; Alohaly, Alhanoof;Bedoya, Juan ...
R41ES030274 Int J Mol Sci (2019 Dec02)
31810189
2019
Excision of Oxidatively Generated Guanine Lesionsby Competing Base and Nucleotide Excision Repair M...
Shafirovich, Vladimir;Kropachev, Konstantin;Kolbanovskiy, Marina;Geacintov, Nicholas E
R01ES027059 Chem Res Toxicol (201904 15)
30688445
2019
Exposure to polybrominated diphenyl ethers (PBDEs)during childhood and adiposity measures at age 8 ...
Vuong, Ann M; Braun,Joseph M; Wang,Zhiyang; Yolton,Kimberly; Xie,Changchun; Sjodin,Andrea ...
P30ES006096,R01ES025214,T32ES010957
Environ Int (2019 02) 30529839
2019
FeatSNP: An Interactive Database for Brain-SpecificEpigenetic Annotation of Human SNPs.
Ma, Chun-Yu; Madden,Pamela; Gontarz, Paul;Wang, Ting; Zhang, Bo
U24ES026699 Front Genet (2019) 31001319
2019
Fluorescent 5-Pyrimidine and 8-Purine NucleosidesModified with an N-Unsubstituted 1,2,3-Triazol-4-y ...
Wen, Zhiwei; Tuttle,Paloma R; Howlader, AHasan; Vasilyeva,Anna; Gonzalez, Laura;Tangar, An ...
R01ES023569 J Org Chem (2019 03 15) 30806513
2019
Formaldehyde, Epigenetics, and Alzheimer's Disease. Wang, Fei; Chen,Danqi; Wu, Peipei;Klein, Catherine; Jin,Chunyuan
P30ES000260,R01ES029359
Chem Res Toxicol (201905 20)
30964647
2019
Generation of 8-oxo-7,8-dihydroguanine inG-Quadruplexes Models of Human TelomereSequences by One-e ...
Merta, Tomasz J;Geacintov, Nicholas E;Shafirovich, Vladimir
R01ES027059 Photochem Photobiol(2019 01)
29679477
2019
Generation of Human Primordial Germ Cell-like Cellsat the Surface of Embryoid Bodies from Primed-pl ...
Mitsunaga, Shino;Shioda, Keiko;Isselbacher, Kurt J;Hanna, Jacob H;Shioda, Toshi
R01ES023316,R01ES023316
J Vis Exp (2019 01 11) 30688291
2019
Genetic and environmental perturbations lead toregulatory decoherence.
Lea, Amanda;Subramaniam, Meena;Ko, Arthur; Lehtimäki,Terho; Raitoharju,Emma; Kähönen, Mika...
R01ES029929 Elife (2019 03 05) 30834892
2019
Genetic predisposition to mosaic Y chromosome lossin blood.
Thompson, Deborah J;Genovese, Giulio;Halvardson, Jonatan;Ulirsch, Jacob C;Wright, Daniel J; ...
DP2ES030554 Nature (2019 11) 31748747
2019
Genome-wide mapping of nucleotide excision repairwith XR-seq.
Hu, Jinchuan; Li,Wentao; Adebali,Ogun; Yang, Yanyan;Oztas, Onur; Selby,Christopher P; Sanc ...
P30ES010126,R01ES027255
Nat Protoc (2019 01) 30552409
2019
Genome-wide RNA pol II initiation and pausing inneural progenitors of the rat.
Scheidegger, Adam;Dunn, Carissa J;Samarakkody, Ann;Koney, NiiKoney-Kwaku; Perley,Danielle; ...
R01ES028738 BMC Genomics (2019 Jun11)
31185909
2019
Genomic sites hypersensitive to ultraviolet radiation. Premi, Sanjay; Han,Lynn; Mehta, Sameet;Knight, James; Zhao,Dejian; Palmatier, MegA; Kornac ...
R01ES030562 Proc Natl Acad Sci U S A(2019 11 26)
31723047
2019
Genomic Tools for Environmental Epigenetics andImplications for Public Health.
Perera, Bambarendage PU; Svoboda, Laurie;Dolinoy, Dana C
P30ES017885,T32ES007062,U01ES026697
Curr Opin Toxicol (2019Dec)
31763499
2019
Glutamine Metabolism Is Required for CollagenProtein Synthesis in Lung Fibroblasts.
Hamanaka, Robert B;O'Leary, Erin M; Witt,Leah J; Tian, Yufeng;Gökalp, Gizem A;Meliton, Ang ...
P30ES027792,R01ES015024,U01ES026718
Am J Respir Cell Mol Biol(2019 11)
30973753
2019
Guidelines for DNA recombination and repair studies:Mechanistic assays of DNA repair processes.
Klein, Hannah L; Ang,Kenny K H; Arkin,Michelle R; Beckwitt,Emily C; Chang,Yi-Hsuan; Fan, J ...
R01ES007061 Microb Cell (2019 Jan 07) 30652106
2019
GWAS of mosaic loss of chromosome Y highlightsgenetic effects on blood cell differentiation.
Terao, Chikashi;Momozawa, Yukihide;Ishigaki, Kazuyoshi;Kawakami, Eiryo;Akiyama, Masato; Loh...
DP2ES030554 Nat Commun (2019 10 17) 31624269
2019
High-throughput Evaluation of Protein Migration andLocalization after Laser Micro-Irradiation.
Oeck, Sebastian;Malewicz, Nathalie M;Krysztofiak, Adam;Turchick, Audrey;Jendrossek, Verena; ...
R01ES005775 Sci Rep (2019 02 28) 30816253
2019
Human DNA polymerase η has reverse transcriptaseactivity in cellular environments.
Su, Yan; Ghodke,Pratibha P; Egli, Martin;Li, Lin; Wang,Yinsheng; Guengerich,F Peter
R01ES010546,R01ES025121,R01ES026955
J Biol Chem (2019 04 12) 30842261
2019
Hydrolyzable Tannins Are Iron Chelators That InhibitDNA Repair Enzyme ALKBH2.
Chen, Fangyi; Tang, Qi;Ma, Hang; Bian, Ke;Seeram, Navindra P; Li,Deyu
R01ES028865,R01ES028865
Chem Res Toxicol (201906 17)
31088072
2019
Hypovitaminosis D exacerbates the DNA damage loadin human uterine fibroids, which is ameliorated by ...
Ali, Mohamed; Shahin,Sara Mahmoud; Sabri,Nagwa Ali; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 Acta Pharmacol Sin (2019Jul)
30478352
2019
Identification of Steps in the Pathway of ArsenosugarBiosynthesis.
Xue, Xi-Mei; Ye, Jun;Raber, Georg; Rosen,Barry P; Francesconi,Kevin; Xiong, Chan;Zhu, Zhe ...
R01ES023779 Environ Sci Technol (201901 15)
30525501
2019
Identification of the novel Ido1 imprinted locus and itspotential epigenetic role in pregnancy loss ...
Spinelli, Philip;Latchney, Sarah E;Reed, Jasmine M;Fields, Ashley; Baier,Brian S; Lu, Xian ...
P30ES001247,R01ES029469,T32ES007026
Hum Mol Genet (2019 0215)
30403776
2019
Impacts of air pollution, temperature, and relativehumidity on leukocyte distribution: An epigeneti ...
Gao, Xu; Colicino,Elena; Shen, Jincheng;Kioumourtzoglou,Marianthi-Anna; Just,Allan C; Nwana ...
P30ES009089,R01ES025225,R01ES027747
Environ Int (2019 05) 30826618
2019
In utero tobacco smoke exposure, DNA methylation,and asthma in Latino children.
Neophytou, Andreas M;Oh, Sam S; Hu,Donglei; Huntsman,Scott; Eng, Celeste;Rodríguez-Santana, ...
R00ES027511 Environ Epidemiol (2019Jun)
31342008
2019
Integration of curated and high-throughput screeningdata to elucidate environmental influences on d ...
Kosnik, Marissa B;Planchart, Antonio;Marvel, Skylar W; Reif,David M; Mattingly,Carolyn J
P30ES025128,R01ES014065,R56ES030007,T32ES007046
Comput Toxicol (2019Nov)
31453412
2019
Integrative Network Analysis Linking ClinicalOutcomes With Environmental Exposures andMolecular Va ...
Thakar, Juilee;Thatcher, Thomas H;Smith, Matthew Ryan;Woeller, Collynn F;Walker, Douglas I; ...
P30ES001247,P30ES019776,R01ES023485
J Occup Environ Med(2019 12)
31800452
2019
Interplay between DNA Polymerases and DNALigases: Influence on Substrate Channeling and theFidelit ...
Çağlayan, Melike R00ES026191 J Mol Biol (2019 05 17) 31034893
2019
Long-term, genome-wide kinetic analysis of the effectof the circadian clock and transcription on th ...
Yang, Yanyan; Liu,Zhenxing; Selby,Christopher P; Sancar,Aziz
P30ES010126,R01ES027255
J Biol Chem (2019 08 09) 31217280
2019
Low-dose cadmium disrupts mitochondrial citric acidcycle and lipid metabolism in mouse lung.
Hu, Xin; Chandler,Joshua D; Park, Soojin;Liu, Ken; Fernandes,Jolyn; Orr, Michael;Smith, M ...
P30ES019776,R01ES023485,U2CES026560
Free Radic Biol Med (201902 01)
30529385
2019
Low-dose cadmium potentiates lung inflammatoryresponse to 2009 pandemic H1N1 influenza virus inmic ...
Chandler, Joshua D; Hu,Xin; Ko, Eun-Ju; Park,Soojin; Fernandes,Jolyn; Lee, Young-Tae;Orr, ...
R01ES023485 Environ Int (2019 06) 30999129
2019
m6A mRNA demethylase FTO regulates melanomatumorigenicity and response to anti-PD-1 blockade.
Yang, Seungwon; Wei,Jiangbo; Cui,Yan-Hong; Park,Gayoung; Shah, Palak;Deng, Yu; Aplin, And...
P30ES027792,R01ES024373,R01ES030546,R01ES030576
Nat Commun (2019 06 25) 31239444
2019
Maintenance of CTCF- and TranscriptionFactor-Mediated Interactions from the Gametes to theEarly Mo ...
Jung, Yoon Hee;Kremsky, Isaac; Gold,Hannah B; Rowley, MJordan; Punyawai,Kanchana; Buonanott ...
R01ES027859,R01ES027859
Mol Cell (2019 07 11) 31056445
2019
Maternal cadmium exposure in the mouse leads toincreased heart weight at birth and programs suscept ...
Hudson, Kathleen M;Belcher, Scott M;Cowley, Michael
K22ES027510,P30ES025128
Sci Rep (2019 09 19) 31537853
2019
Maternal circadian disruption is associated withvariation in placental DNA methylation.
Clarkson-Townsend,Danielle A; Everson,Todd M; Deyssenroth,Maya A; Burt, AmberA; Hermetz, Ka ...
P01ES022832,P30ES019776,P30ES023515,R01ES025145,R01ES025145,R24ES028507,T32ES012870
PLoS One (2019) 31026301
2019
Mechanisms of Chromium-Induced Toxicity. DesMarais, Thomas L;Costa, Max
P30ES000260,R01ES029359
Curr Opin Toxicol (2019Apr)
31511838
2019
Mechanisms of MTH1 inhibition-induced DNA strandbreaks: The slippery slope from the oxidized nucleo ...
Rai, Priyamvada;Sobol, Robert W
P01ES028949,R01ES014811,U01ES029518,U01ES029518
DNA Repair (Amst) (201905)
30852368
2019
Mechanisms underlying aflatoxin-associatedmutagenesis - Implications in carcinogenesis.
McCullough, AmandaK; Lloyd, R Stephen
R01ES029357 DNA Repair (Amst) (201905)
30897375
2019
Mechanistic Study of TTF-1 Modulation of CellularSensitivity to Cisplatin.
Phelps, Cody A;Lindsey-Boltz, Laura;Sancar, Aziz; Mu,David
P30ES010126,R01ES027255
Sci Rep (2019 05 29) 31142791
2019
Meta-analysis of epigenome-wide association studiesin neonates reveals widespread differential DNA ...
Küpers, Leanne K;Monnereau, Claire;Sharp, Gemma C;Yousefi, Paul; Salas,Lucas A; Ghantous, ...
P30ES023515,R01ES013744,R01ES025531,R01ES025574,R24ES028507,R24ES028522,R24ES028531
Nat Commun (2019 04 23) 31015461
2019
Metabolic perturbations in classic galactosemiabeyond the Leloir pathway: Insights from an untarget...
Taylor Fischer, S;Frederick, Allison B;Tran, ViLinh; Li,Shuzhao; Jones, DeanP; Fridovich-Ke ...
P30ES019776,R01ES023485
J Inherit Metab Dis (201903)
30667068
2019
Metabolome-Wide Association Study of Deploymentto Balad, Iraq or Bagram, Afghanistan.
Go, Young-Mi; Smith,Matthew R; Walker,Douglas I; Uppal,Karan; Rohrbeck,Patricia; Krahl, Pa ...
P30ES019776,R01ES023485
J Occup Environ Med(2019 12)
31800448
2019
Metabolomic assessment of exposure to near-highwayultrafine particles.
Walker, Douglas I;Lane, Kevin J; Liu,Ken; Uppal, Karan;Patton, Allison P;Durant, John L; J ...
P30ES019776,R01ES023485
J Expo Sci EnvironEpidemiol (2019 06)
30518795
2019
Metabolomic Responses to Manganese Dose inSH-SY5Y Human Neuroblastoma Cells.
Fernandes, Jolyn;Chandler, Joshua D;Liu, Ken H; Uppal,Karan; Hao, Li; Hu,Xin; Go, Young-M ...
P30ES019776,R01ES023485
Toxicol Sci (2019 05 01) 30715528
2019
Metabolomics of childhood exposure to perfluoroalkylsubstances: a cross-sectional study.
Kingsley, Samantha L;Walker, Douglas I;Calafat, Antonia M;Chen, Aimin;Papandonatos, George...
P30ES019776,P30ES023515,P42ES013660,R01ES025214,U2CES026561
Metabolomics (2019 0621)
31227916
2019
Metal carcinogen exposure induces cancer stemcell-like property through epigenetic reprograming: A...
Wang, Zhishan; Yang,Chengfeng
P30ES026529,R01ES026151,R01ES028256
Semin Cancer Biol (201908)
30641125
2019
Metformin Targets Mitochondrial Electron Transportto Reduce Air-Pollution-Induced Thrombosis.
Soberanes, Saul;Misharin, Alexander V;Jairaman, Amit;Morales-Nebreda,Luisa;McQuattie-Piment ...
P30ES027792,R01ES015024,U01ES026718
Cell Metab (2019 02 05) 30318339
2019
Methods to Study Trinucleotide Repeat InstabilityInduced by DNA Damage and Repair.
Lai, Yanhao; Lei,Ruipeng; Ren, Yaou;Liu, Yuan
R01ES023569 Methods Mol Biol (2019) 31127571
2019
MiR223-3p promotes synthetic lethality inBRCA1-deficient cancers.
Srinivasan, Gayathri;Williamson, ElizabethA; Kong, Kimi; Jaiswal,Aruna S; Huang,Guangcun; K ...
R01ES007061 Proc Natl Acad Sci U S A(2019 08 27)
31395736
2019
Mitochondria in precision medicine; linkingbioenergetics and metabolomics in platelets.
Chacko, Balu K; Smith,Matthew R; Johnson,Michelle S; Benavides,Gloria; Culp, Matilda L;Pill ...
P30ES019776,R01ES023485,U2CES026560
Redox Biol (2019 04) 30877854
2019
Mitochondrial DNA: Epigenetics and environment. Sharma, Nidhi; Pasala,Monica S; Prakash,Aishwarya
R01ES030084,R01ES030084
Environ Mol Mutagen(2019 10)
31335990
2019
Multivariate modeling of engineered nanomaterialfeatures associated with developmental toxicity.
To, Kimberly T;Truong, Lisa; Edwards,Sabrina; Tanguay,Robert L; Reif, DavidM
P30ES025128,R56ES030007,T32ES007329,U01ES027294,U24ES026946
NanoImpact (2019 Apr) 32133425
2019
Murine models of accelerated aging andmusculoskeletal disease.
Hambright, William S;Niedernhofer, Laura J;Huard, Johnny;Robbins, Paul D
U01ES029603 Bone (2019 08) 30844492
2019
Mutagenic Replication of the Major OxidativeAdenine Lesion 7,8-Dihydro-8-oxoadenine by HumanDNA Po ...
Koag, Myong-Chul;Jung, Hunmin; Lee,Seongmin
R01ES026676 J Am Chem Soc (2019 0320)
30817143
2019
Myometrial progesterone hyper-responsivenessassociated with increased risk of human uterine fibroid...
Omar, Mona; Laknaur,Archana; Al-Hendy,Ayman; Yang, Qiwei
R01ES028615 BMC Womens Health(2019 07 09)
31288815
2019
N-Acetylcysteine: Antioxidant, Aldehyde Scavenger,and More.
Zhitkovich, Anatoly R01ES008786,R01ES028072
Chem Res Toxicol (201907 15)
31046246
2019
Natural variation in C. elegans arsenic toxicity isexplained by differences in branched chain amino ...
Zdraljevic, Stefan; Fox,Bennett William;Strand, Christine;Panda, Oishika; Tenjo,Francisco J ...
R01ES029930 Elife (2019 04 08) 30958264
2019
Neonatal Adipocytokines and Longitudinal Patterns ofChildhood Growth.
Buck, Catherine O;Eliot, Melissa N;Kelsey, Karl T; Chen,Aimin; Kalkwarf,Heidi; Lanphear, B ...
R01ES025214 Obesity (Silver Spring)(2019 08)
31199076
2019
Nickel-induced transcriptional changes persist postexposure through epigenetic reprogramming.
Jose, Cynthia C; Wang,Zhenjia; Tanwar, VinaySingh; Zhang, Xiaoru;Zang, Chongzhi;Cuddapah, ...
P30ES000260,R01ES024727
Epigenetics Chromatin(2019 12 19)
31856895
2019
NuA4 acetyltransferase is required for efficientnucleotide excision repair in yeast.
Hodges, Amelia J;Plummer, Dalton A;Wyrick, John J
R01ES028698 DNA Repair (Amst) (201901)
30473425
2019
Nucleotide Excision Repair and Impact ofSite-Specific 5',8-Cyclopurine and Bulky DNALesions on the ...
Shafirovich, Vladimir;Kolbanovskiy, Marina;Kropachev, Konstantin;Liu, Zhi; Cai, Yuquin;Terz ...
R01ES025987 Biochemistry (2019 02 12) 30570250
2019
Nucleotide excision repair capacity increases duringdifferentiation of human embryonic carcinoma ce ...
Li, Wentao; Liu,Wenjie; Kakoki,Ayano; Wang, Rujin;Adebali, Ogun; Jiang,Yuchao; Sancar, Az ...
P30ES010126,R01ES027255
J Biol Chem (2019 04 12) 30808711
2019
Organization of DNA damage, excision repair, andmutagenesis in chromatin: A genomic perspective.
Mao, Peng; Wyrick,John J
R01ES028698,R21ES029302,R21ES029655
DNA Repair (Amst) (201909)
31307926
2019
Overall gestational weight gain mediates therelationship between maternal and child obesity.
Josey, Michele J;McCullough, Lauren E;Hoyo, Cathrine;Williams-DeVane,ClarLynda
R24ES028531 BMC Public Health (2019Aug 07)
31391077
2019
Overexpression of hsa-miR-186 induces chromosomalinstability in arsenic-exposed human keratinocytes ...
Wu, Jiguo; FerragutCardoso, Ana P; States,Vanessa A R;Al-Eryani, Laila; Doll,Mark; Wise, S ...
R01ES027778 Toxicol Appl Pharmacol(2019 09 01)
31176655
2019
p53 activation by Cr(VI): a transcriptionally limitedresponse induced by ATR kinase in S-phase.
Luczak, Michal W;Krawic, Casey;Zhitkovich, Anatoly
R01ES008786,R01ES028072
Toxicol Sci (2019 Aug 06) 31388677
2019
Pach-ing It in: The Peculiar Organization ofMammalian Pachytene Chromosomes.
Jung, Yoon Hee;Corces, Victor G
R01ES027859,R01ES027859
Mol Cell (2019 02 07) 30735652
2019
PARP1 is a versatile factor in the regulation of mRNAstability and decay.
Matveeva, Elena A;Mathbout, Lein F;Fondufe-Mittendorf,Yvonne N
R01ES024478 Sci Rep (2019 03 06) 30842529
2019
Pathways of arsenic uptake and efflux. Garbinski, Luis D;Rosen, Barry P; Chen,Jian
R01ES023779 Environ Int (2019 05) 30852446
2019
Phytochelatin database: a resource for phytochelatincomplexes of nutritional and environmental meta ...
Dennis, Kristine K;Uppal, Karan; Liu, KenH; Ma, Chunyu; Liang,Bill; Go, Young-Mi;Jones, D ...
P30ES019776,R01ES023485,U2CES030163
Database (Oxford) (201901 01)
31267134
2019
POLE proofreading defects: Contributions tomutagenesis and cancer.
Park, Vivian S; Pursell,Zachary F
R01ES028271 DNA Repair (Amst) (201904)
30818169
2019
Population-Based Analysis of DNA Damage andEpigenetic Effects of 1,3-Butadiene in the Mouse.
Lewis, Lauren;Borowa-Mazgaj,Barbara; de Conti,Aline; Chappell, GraceA; Luo, Yu-Syuan;Bodna ...
R01ES029911 Chem Res Toxicol (201905 20)
30990016
2019
Prenatal and childhood exposure to poly- andperfluoroalkyl substances (PFAS) and cognitivedevelopm ...
Vuong, Ann M; Yolton,Kimberly; Xie,Changchun; Dietrich,Kim N; Braun, JosephM; Webster, Gle ...
P30ES006096,R01ES025214,T32ES010957
Environ Res (2019 05) 30818233
2019
Prenatal Bisphenol A Exposure in Mice InducesMultitissue Multiomics Disruptions Linking toCardiome ...
Shu, Le; Meng,Qingying; Diamante,Graciel; Tsai, Brandon;Chen, Yen-Wei;Mikhail, Andrew; Luk...
R01ES027487,R01ES027487
Endocrinology (2019 0201)
30566610
2019
Probing the Effect of Bulky Lesion-InducedReplication Fork Conformational Heterogeneity Using4-Ami ...
Cai, Ang; Bian, Ke;Chen, Fangyi; Tang, Qi;Carley, Rachel; Li,Deyu; Cho, Bongsup P
R01ES028865,R01ES028865
Molecules (2019 Apr 20) 31009995
2019
Processing of N5-substituted formamidopyrimidineDNA adducts by DNA glycosylases NEIL1 andNEIL3.
Minko, Irina G;Christov, Plamen P; Li,Liang; Stone, MichaelP; McCullough,Amanda K; Lloyd, ...
R01ES029357 DNA Repair (Amst) (201901)
30448017
2019
Promutagenicity of 8-Chloroguanine, A MajorInflammation-Induced Halogenated DNA Lesion.
Kou, Yi; Koag,Myong-Chul; Lee,Seongmin
R01ES026676 Molecules (2019 Sep 27) 31569643
2019
Protection of abasic sites during DNA replication by astable thiazolidine protein-DNA cross-link.
Thompson, Petria S;Amidon, Katherine M;Mohni, Kareem N;Cortez, David;Eichman, Brandt F
R01ES030575 Nat Struct Mol Biol (201907)
31235915
2019
Quantification of DNA Lesions Induced by4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol inMammalian ...
Guo, Su; Leng, Jiapeng;Tan, Ying; Price,Nathan E; Wang,Yinsheng
R01ES025121,T32ES018827
Chem Res Toxicol (201904 15)
30714728
2019
R-loop formation by dCas9 is mutagenic inSaccharomyces cerevisiae.
Laughery, Marian F;Mayes, Hannah C;Pedroza, Ivan K;Wyrick, John J
R01ES028698 Nucleic Acids Res (201903 18)
30590793
2019
Rad52 Restrains Resection at DNA Double-StrandBreak Ends in Yeast.
Yan, Zhenxin; Xue,Chaoyou; Kumar,Sandeep; Crickard, JBrooks; Yu, Yang;Wang, Weibin; Pham,...
R01ES007061 Mol Cell (2019 12 05) 31542296
2019
Random Walk Enzymes: Information Theory,Quantum Isomorphism, and Entropy Dispersion.
Mak, Chi H; Pham,Phuong; Goodman,Myron F
R35ES028343 J Phys Chem A (2019 Apr04)
30848911
2019
Recurrent Noncoding Mutations in Skin Cancers: UVDamage Susceptibility or Repair Inhibition as Prim ...
Roberts, Steven A;Brown, Alexander J;Wyrick, John J
R01ES028698,R21ES029302
Bioessays (2019 03) 30801747
2019
Redox Systems Biology of Nutrition and OxidativeStress.
Dennis, Kristine K; Go,Young-Mi; Jones, DeanP
P30ES019776,R01ES023485
J Nutr (2019 04 01) 30949678
2019
Regulatory control of Sgs1 and Dna2 duringeukaryotic DNA end resection.
Xue, Chaoyou; Wang,Weibin; Crickard, JBrooks; Moevus,Corentin J; Kwon,Youngho; Sung, Patri ...
R01ES007061 Proc Natl Acad Sci U S A(2019 03 26)
30850524
2019
Repair and translesion synthesis of O6-alkylguanineDNA lesions in human cells.
Du, Hua; Wang,Pengcheng; Li, Lin;Wang, Yinsheng
R01ES025121 J Biol Chem (2019 07 19) 31167778
2019
Replication Stress and Consequential Instability of theGenome and Epigenome.
Tsegay, Pawlos S; Lai,Yanhao; Liu, Yuan
R01ES023569 Molecules (2019 Oct 27) 31717862
2019
Replication-Coupled DNA Repair. Cortez, David R01ES030575 Mol Cell (2019 06 06) 31173722
2019 Ribose-Map: a bioinformatics toolkit to mapribonucleotides embedded in genomic DNA.
Gombolay, Alli L;Vannberg, Fredrik O;Storici, Francesca
R01ES026243 Nucleic Acids Res (201901 10)
30272244
2019
Ribosomal DNA and the Nucleolus as Keystones ofNuclear Architecture, Organization, and Function.
Cerqueira, Amanda V;Lemos, Bernardo
R01ES027981 Trends Genet (2019 10) 31447250
2019
Ribosomal DNA harbors an evolutionarily conservedclock of biological aging.
Wang, Meng; Lemos,Bernardo
P30ES000002,R01ES027981
Genome Res (2019 03) 30765617
2019
Role of CTCF in DNA damage response. Tanwar, Vinay Singh;Jose, Cynthia C;Cuddapah, Suresh
P30ES000260,R01ES024727
Mutat Res (2019 Apr -Jun)
31395350
2019
Role of RNase H enzymes in maintaining genomestability in Escherichia coli expressing a steric-gate ...
Walsh, Erin; Henrikus,Sarah S; Vaisman,Alexandra;Makiela-Dzbenska,Karolina; Armstrong,Thom ...
R35ES028343 DNA Repair (Amst) (201912)
31543434
2019
Role of Y-family translesion DNA polymerases inreplication stress: Implications for new cancer ther ...
Tonzi, Peter; Huang,Tony T
R01ES025166 DNA Repair (Amst) (201906)
30954011
2019
Rotational and translational positions determine thestructural and dynamic impact of a single ribon ...
Fu, Iwen; Smith,Duncan J; Broyde, Suse
R01ES025987 DNA Repair (Amst) (201901)
30522887
2019
Sense and sensibility: ATM oxygen stress signalingmanages brain cell energetics.
Schlacher, Katharina R01ES029680 J Cell Biol (2019 03 04) 30782782
2019
Sex-specific differences in genotoxic and epigeneticeffects of 1,3-butadiene among mouse tissues.
Lewis, Lauren;Chappell, Grace A;Kobets, Tetyana;O'Brian, Bridget E;Sangaraju, Dewakar;Kosy ...
P30ES029067,R01ES029911
Arch Toxicol (2019 03) 30552462
2019
Short-term ambient particle radioactivity level andrenal function in older men: Insight from the No ...
Gao, Xu; Koutrakis,Petros; Blomberg,Annelise J; Coull,Brent; Vokonas, Pantel;Schwartz, Joe ...
P30ES009089,R01ES025225,R01ES027747
Environ Int (2019 10) 31336254
2019
Simple CRISPR-Cas9 Genome Editing inSaccharomyces cerevisiae.
Laughery, Marian F;Wyrick, John J
R01ES028698,R21ES029302,R21ES029655
Curr Protoc Mol Biol(2019 12)
31763795
2019
Single-molecule visualization of human BLM helicaseas it acts upon double- and single-stranded DNA ...
Xue, Chaoyou; Daley,James M; Xue, Xiaoyu;Steinfeld, Justin; Kwon,Youngho; Sung,Patrick; Gr ...
R01ES007061 Nucleic Acids Res (201912 02)
31544923
2019
Single-nucleotide resolution analysis of nucleotideexcision repair of ribosomal DNA in humans and m ...
Yang, Yanyan; Hu,Jinchuan; Selby,Christopher P; Li,Wentao; Yimit, Askar;Jiang, Yuchao; San ...
P30ES010126,R01ES027255
J Biol Chem (2019 01 04) 30413533
2019
SLIRP Interacts with Helicases to Facilitate2'-O-Methylation of rRNA and to Promote Translation.
Li, Lin; Miao, Weili;Williams, Preston; Guo,Cheng; Wang,Yinsheng
R01ES025121 J Am Chem Soc (2019 0717)
31260285
2019
Snacking frequency and dietary intake in toddlers andpreschool children.
Xue, Hong; Maguire,Rachel L; Liu, Jin;Kollins, Scott H;Murphy, Susan K;Hoyo, Cathrine; Fue ...
P30ES025128,R24ES028531
Appetite (2019 11 01) 31302102
2019
Sperm epimutation biomarkers of obesity andpathologies following DDT induced epigenetictransgenera ...
King, Stephanie E;McBirney, Margaux;Beck, Daniel;Sadler-Riggleman,Ingrid; Nilsson, Eric;Sk ...
R01ES012974,R01ES012974
Environ Epigenet (2019Apr)
31186947
2019
Statistical Approaches for Investigating Periods ofSusceptibility in Children's Environmental Healt ...
Buckley, Jessie P;Hamra, Ghassan B;Braun, Joseph M
R01ES025214,R01ES027408
Curr Environ Health Rep(2019 03)
30684243
2019
Structural basis for the bypass of the majoroxaliplatin-DNA adducts by human DNA polymeraseη.
Ouzon-Shubeita, Hala;Baker, Meghan; Koag,Myong-Chul; Lee,Seongmin
R01ES026676 Biochem J (2019 02 28) 30709915
2019
Structural consequence of the most frequentlyrecurring cancer-associated substitution in DNApolyme ...
Parkash, Vimal;Kulkarni, Yashraj; TerBeek, Josy;Shcherbakova, PolinaV; Kamerlin, ShinaCaro ...
R01ES015869 Nat Commun (2019 01 22) 30670696
2019
Structure and mechanism of pyrimidine-pyrimidone(6-4) photoproduct recognition by the Rad4/XPC nucl...
Paul, Debamita; Mu,Hong; Zhao, Hong;Ouerfelli, Ouathek;Jeffrey, Philip D;Broyde, Suse; Min ...
R01ES025987 Nucleic Acids Res (201907 09)
31106376
2019
SUMOning the base excision repair machinery fordifferentiation.
Wiest, Nathaniel E;Tomkinson, Alan E
R01ES012512 EMBO J (2019 01 03) 30545824
2019
Synthesis and Characterization of Site-Specific O6-Alkylguanine DNA-Alkyl Transferase-Oligonucleoti...
Ghodke, Pratibha P;Albertolle, Matthew E;Johnson, Kevin M;Guengerich, F Peter
R01ES010546,R01ES026955,T32ES007028
Curr Protoc Nucleic AcidChem (2019 03)
30657645
2019
Targeted and Persistent 8-Oxoguanine Base Damage atTelomeres Promotes Telomere Loss and Crisis.
Fouquerel, Elise;Barnes, Ryan P; Uttam,Shikhar; Watkins,Simon C; Bruchez,Marcel P; Opresko, ...
R00ES027028,R33ES025606
Mol Cell (2019 07 11) 31101499
2019
Targeted Quantitative Proteomic Approach forHigh-Throughput Quantitative Profiling of SmallGTPases ...
Huang, Ming; Darvas,Martin; Keene, C Dirk;Wang, Yinsheng
R01ES025121,T32ES018827
Anal Chem (2019 10 01) 31460748
2019
Targeted Quantitative Proteomics RevealedArsenite-induced Proteasomal Degradation of RhoB inFibrob ...
Tam, Lok Ming; Huang,Ming; Wang, Yinsheng
R01ES025121,T32ES018827
Chem Res Toxicol (201907 15)
31140275
2019
Targeting phosphatases in cancer: suppression of manyversus the ablation of one.
D'Arcy, Brandon M;Prakash, Aishwarya;Honkanen, Richard E
R01ES030084,R01ES030084
Oncotarget (2019 Nov 12) 31762936
2019
The antibiotic action of methylarsenite is an emergentproperty of microbial communities.
Chen, Jian; Yoshinaga,Masafumi; Rosen,Barry P
R01ES023779 Mol Microbiol (2019 02) 30520200
2019
The BRCA Tumor Suppressor Network inChromosome Damage Repair by HomologousRecombination.
Zhao, Weixing; Wiese,Claudia; Kwon,Youngho; Hromas,Robert; Sung, Patrick
R01ES007061 Annu Rev Biochem (201906 20)
30917004
2019
The contribution of parent-to-offspring transmission oftelomeres to the heritability of telomere le ...
Delgado, Dayana A;Zhang, Chenan;Gleason, Kevin;Demanelis, Kathryn;Chen, Lin S; Gao,Jianju ...
P30ES027792,P42ES010349,R24ES028532,R35ES028379
Hum Genet (2019 Jan) 30536049
2019
The effect of age on DNA methylation in whole bloodamong Bangladeshi men and women.
Jansen, Rick J; Tong,Lin; Argos, Maria;Jasmine, Farzana;Rakibuz-Zaman,Muhammad; Sarwar,Go ...
P30ES027792,P42ES010349,R24ES028532,R35ES028379
BMC Genomics (2019 Sep10)
31506065
2019
The epigenomic landscape of transposable elementsacross normal human development and anatomy.
Pehrsson, Erica C;Choudhary, Mayank NK; Sundaram, Vasavi;Wang, Ting
U24ES026699 Nat Commun (2019 12 10) 31822674
2019
The Impact of Minor-GrooveN2-Alkyl-2'-deoxyguanosine Lesions on DNAReplication in Human Cells.
Wu, Jun; Du, Hua; Li,Lin; Price, Nathan E;Liu, Xiaochuan; Wang,Yinsheng
R01ES025121,T32ES018827
ACS Chem Biol (2019 0816)
31347832
2019
The Rad51 paralogs facilitate a novel DNA strandspecific damage tolerance pathway.
Rosenbaum, Joel C;Bonilla, Braulio;Hengel, Sarah R; Mertz,Tony M; Herken,Benjamin W; Kazemi ...
R01ES007061 Nat Commun (2019 08 05) 31383866
2019
The RecQ helicase Sgs1 drives ATP-dependentdisruption of Rad51 filaments.
Crickard, J Brooks;Xue, Chaoyou; Wang,Weibin; Kwon,Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 Nucleic Acids Res (201905 21)
30916344
2019
The Role of Dynamic m6 A RNA Methylation inPhotobiology.
Robinson, Myles; Shah,Palak; Cui, Yan-Hong;He, Yu-Ying
P30ES027792,R01ES024373,R01ES030576
Photochem Photobiol(2019 01)
29729018
2019
Tightly linked antagonistic-effect loci underliepolygenic phenotypic variation in C. elegans.
Bernstein, Max R;Zdraljevic, Stefan;Andersen, Erik C;Rockman, Matthew V
R01ES029930 Evol Lett (2019 Oct) 31636939
2019
Transcription shapes DNA replication initiation andtermination in human cells.
Chen, Yu-Hung;Keegan, Sarah; Kahli,Malik; Tonzi, Peter;Fenyö, David; Huang,Tony T; Smith, ...
R01ES025166 Nat Struct Mol Biol (201901)
30598550
2019
Transcriptional Bypass of DNA-Protein andDNA-Peptide Conjugates by T7 RNA Polymerase.
Ji, Shaofei; Thomforde,Jenna; Rogers, Colette;Fu, Iwen; Broyde, Suse;Tretyakova, Natalia Y
R01ES023350,R01ES025987
ACS Chem Biol (2019 1220)
31573793
2019
Transcriptome Analysis Reveals Distinct Responses toPhysiologic versus Toxic Manganese Exposure in ...
Fernandes, Jolyn;Chandler, Joshua D;Lili, Loukia N; Uppal,Karan; Hu, Xin; Hao,Li; Go, You ...
P30ES019776,R01ES023485
Front Genet (2019) 31396262
2019
Transgenerational effects of obesogens. Lee, Michelle Kira;Blumberg, Bruce
R01ES023316,R01ES023316
Basic Clin PharmacolToxicol (2019 Aug)
30801972
2019
Transgenerational Self-Reconstruction of DisruptedChromatin Organization After Exposure To An Envir...
Diaz-Castillo, Carlos;Chamorro-Garcia,Raquel; Shioda, Toshi;Blumberg, Bruce
P30ES007048,R01ES023316,R01ES023316
Sci Rep (2019 09 10) 31506492
2019
Transgenerational sperm DNA methylationepimutation developmental origins following ancestralvinclo ...
Skinner, Michael K;Nilsson, Eric;Sadler-Riggleman,Ingrid; Beck, Daniel;Ben Maamar, Millissi ...
R01ES012974,R01ES012974
Epigenetics (2019 07) 31079544
2019
Transposable elements drive widespread expression ofoncogenes in human cancers.
Jang, Hyo Sik; Shah,Nakul M; Du, Alan Y;Dailey, Zea Z;Pehrsson, Erica C;Godoy, Paula M; Zh ...
U24ES026699 Nat Genet (2019 04) 30926969
2019
Unlike the Escherichia coli counterpart, archaealRNase HII cannot process ribose monophosphate abas...
Malfatti, MatildeClarissa; Henneke,Ghislaine; Balachander,Sathya; Koh, KyungDuk; Newnam, Ga ...
R01ES026243 J Biol Chem (2019 08 30) 31300556
2019
Using Collaborative Cross Mouse Population to FillData Gaps in Risk Assessment: A Case Study of Pop...
Luo, Yu-Syuan;Cichocki, Joseph A;Hsieh, Nan-Hung;Lewis, Lauren; Wright,Fred A; Threadgill, ...
P30ES029067,P42ES027704,R01ES029911
Environ Health Perspect(2019 06)
31246107
2019
Using phenome-wide association studies to examinethe effect of environmental exposures on human hea ...
Braun, Joseph M;Kalloo, Geetika;Kingsley, Samantha L;Li, Nan
R01ES025214,R01ES027408
Environ Int (2019 09) 31200158
2019
Virtual Pharmacophore Screening IdentifiesSmall-Molecule Inhibitors of the Rev1-CT/RIRProtein-Prot ...
Dash, Radha C; Ozen,Zuleyha; McCarthy,Kaitlyn R; Chatterjee,Nimrat; Harris, CynthiaA; Rizzo ...
P30ES002109,R35ES028303
ChemMedChem (2019 0904)
31361935
2019
Vitamin C as a Modulator of the Response to CancerTherapy.
Blaszczak, Wiktoria;Barczak, Wojciech;Masternak, Julia;Kopczyński,Przemysław;Zhitkovich, A ...
R01ES008786 Molecules (2019 Jan 28) 30695991
2019
Vitamin C increases DNA breaks and suppresses DNAdamage-independent activation of ATM by bleomycin.
Rubis, Blazej; Luczak,Michal W; Krawic,Casey; Zhitkovich,Anatoly
R01ES008786,R01ES028072
Free Radic Biol Med (201905 20)
30926564
2019
WashU Epigenome Browser update 2019. Li, Daofeng; Hsu, Silas;Purushotham, Deepak;Sears, Renee L; Wang,Ting
U24ES026699 Nucleic Acids Res (201907 02)
31165883
2019
Widespread epigenetic changes to the enhancerlandscape of mouse liver induced by a specificxenobio ...
Rampersaud, Andy;Lodato, Nicholas J;Shin, Aram; Waxman,David J
R01ES024421 Toxicol Sci (2019 Jun 24) 31236583
2019
5-Formylcytosine mediated DNA-protein cross-linksblock DNA replication and induce mutations in huma...
Ji, Shaofei; Fu, Iwen;Naldiga, Spandana;Shao, Hongzhao; Basu,Ashis K; Broyde, Suse;Tretyak ...
R01ES023350,R01ES025987
Nucleic Acids Res (201807 27)
29905846
2018
A DNA nick at Ku-blocked double-strand break endsserves as an entry site for exonuclease 1 (Exo1) o ...
Wang, Weibin; Daley,James M; Kwon,Youngho; Xue, Xiaoyu;Krasner, Danielle S;Miller, Adam S; ...
R01ES007061 J Biol Chem (2018 11 02) 30224356
2018
A high-fat diet alters genome-wide DNA methylationand gene expression in SM/J mice.
Keleher, MadelineRose; Zaidi, Rabab;Hicks, Lauren; Shah,Shyam; Xing, Xiaoyun;Li, Daofeng; ...
U24ES026699 BMC Genomics (2018 Dec07)
30526554
2018
A new mitotic activity comes into focus. Saldivar, Joshua C;Cimprich, Karlene A
R01ES016486 Science (2018 01 05) 29302000
2018
A novel pooled-sample multiplex luminex assay forhigh-throughput measurement of relative telomere l ...
Jasmine, Farzana;Shinkle, Justin;Sabarinathan, Mekala;Ahsan, Habibul; Pierce,Brandon L; Kib ...
R35ES028379 Am J Hum Biol (2018 07) 29527774
2018
A quantitative PCR-based assay reveals thatnucleotide excision repair plays a predominant role in t...
Chesner, Lisa N;Campbell, Colin
R01ES023350 DNA Repair (Amst) (201802)
29413806
2018
A study of telomere length, arsenic exposure, andarsenic toxicity in a Bangladeshi cohort.
Zhang, Chenan;Kibriya, Muhammad G;Jasmine, Farzana; Roy,Shantanu; Gao, Jianjun;Sabarinathan ...
P30ES027792,P42ES010349,R24ES028532,R35ES028379
Environ Res (2018 07) 29567420
2018
Accelerated DNA methylation age and the use ofantihypertensive medication among older adults.
Gao, Xu; Colicino,Elena; Shen, Jincheng;Just, Allan C;Nwanaji-Enwerem,Jamaji C; Wang, Cuic...
P30ES009089,P30ES023515,R01ES025225,R01ES027747
Aging (Albany NY) (201811 10)
30414594
2018
Alterations in sperm DNA methylation, non-codingRNA and histone retention associate with DDT-induce...
Skinner, Michael K;Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;Nilsson, Eri ...
R01ES012974,R01ES012974
Epigenetics Chromatin(2018 02 27)
29482626
2018
Alterations in sperm DNA methylation, non-codingRNA expression, and histone retention mediate vincl ...
Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;McBirney, Margaux;Nilsson, Eric ...
R01ES012974,R01ES012974
Environ Epigenet (2018Apr)
29732173
2018
An intrinsic S/G2 checkpoint enforced by ATR. Saldivar, Joshua C;Hamperl, Stephan;Bocek, Michael J;Chung, Mingyu; Bass,Thomas E; Cisneros ...
R01ES016486 Science (2018 08 24) 30139873
2018
An oxidized abasic lesion inhibits base excision repairleading to DNA strand breaks in a trinucleot ...
Beaver, Jill M; Lai,Yanhao; Rolle, ShantellJ; Weng, Liwei;Greenberg, Marc M;Liu, Yuan
R01ES023569 PLoS One (2018) 29389977
2018
Animal models of endocrine disruption. Patisaul, Heather B;Fenton, Suzanne E;Aylor, David
P30ES025128,U01ES026717
Best Pract Res ClinEndocrinol Metab (201806)
29779582
2018
Arsenic exposure and risk of nonalcoholic fatty liverdisease (NAFLD) among U.S. adolescents and adu ...
Frediani, Jennifer K;Naioti, Eric A; Vos,Miriam B; Figueroa,Janet; Marsit, Carmen J;Welsh, ...
P01ES022832,P30ES019776,R01ES025145,R01ES025145,U2CES026560
Environ Health (2018 0115)
29334960
2018
Arsenic exposure during embryonic developmentalters the expression of the long noncoding RNAgrowth ...
Caldwell, Kevin K;Hafez, Alexander;Solomon, Elizabeth;Cunningham, Matthew;Allan, Andrea M
R01ES019583 Neurotoxicol Teratol (2018Mar - Apr)
29132937
2018
Arsenic-Induced Carcinogenesis: The Impact ofmiRNA Dysregulation.
Cardoso, Ana PFerragut; Al-Eryani,Laila; States, JChristopher
R01ES027778 Toxicol Sci (2018 10 01) 29846715
2018
Arsenite Targets the RING Finger Domain of Rbx1 E3Ubiquitin Ligase to Inhibit Proteasome-Mediated D ...
Jiang, Ji; Tam, LokMing; Wang,Pengcheng; Wang,Yinsheng
R01ES025121 Chem Res Toxicol (201805 21)
29658272
2018
Biochemical Studies and Molecular DynamicSimulations Reveal the Molecular Basis ofConformational C ...
Ye, Fei; Kong,Xiangqian; Zhang, Hao;Liu, Yan; Shao,Zhiyuan; Jin, Jia; Cai,Yi; Zhang, Ruk ...
R01ES011858 ACS Chem Biol (2018 0316)
29381856
2018
Caenorhabditis elegans as an emerging model systemin environmental epigenetics.
Weinhouse, Caren;Truong, Lisa; Meyer,Joel N; Allard, Patrick
P42ES010356,R01ES027487,R01ES027487
Environ Mol Mutagen(2018 08)
30091255
2018
Characterization of a Mouse Model ofBörjeson-Forssman-Lehmann Syndrome.
Cheng, Cheng; Deng,Pan-Yue; Ikeuchi,Yoshiho; Yuede, Carla;Li, Daofeng; Rensing,Nicholas; H ...
U24ES026699 Cell Rep (2018 11 06) 30403997
2018
Cisplatin-DNA adduct repair of transcribed genes iscontrolled by two circadian programs in mouse ti ...
Yang, Yanyan; Adebali,Ogun; Wu, Gang;Selby, Christopher P;Chiou, Yi-Ying;Rashid, Naim; Hu, ...
P30ES010126,R01ES027255
Proc Natl Acad Sci U S A(2018 05 22)
29735688
2018
Co-occurring expression and methylation QTLs allowdetection of common causal variants and shared bi ...
Pierce, Brandon L;Tong, Lin; Argos,Maria; Demanelis,Kathryn; Jasmine,Farzana;Rakibuz-Zaman ...
P30ES027792,P42ES010349,R35ES028379
Nat Commun (2018 02 23) 29476079
2018
Cohort Profile: Pregnancy And Childhood Epigenetics(PACE) Consortium.
Felix, Janine F; Joubert,Bonnie R; Baccarelli,Andrea A; Sharp,Gemma C; Almqvist,Catarina; A ...
P01ES022832,P30ES007048,P30ES017885,P30ES025128,R00ES024116,R01ES025145,R01ES025145,R24ES028507
Int J Epidemiol (2018 0201)
29025028
2018
Comparative properties and functions of type 2 andtype 4 pigeon cryptochromes.
Wang, Xuefeng; Jing,Chengyu; Selby,Christopher P; Chiou,Yi-Ying; Yang,Yanyan; Wu, Wenjian;...
R01ES027255 Cell Mol Life Sci (2018Dec)
30264181
2018
Comprehensive Whole DNA Methylome Analysis byIntegrating MeDIP-seq and MRE-seq.
Xing, Xiaoyun; Zhang,Bo; Li, Daofeng; Wang,Ting
U24ES026699 Methods Mol Biol (2018) 29224147
2018
Computational prediction of CTCF/cohesin-basedintra-TAD loops that insulate chromatin contacts and...
Matthews, Bryan J;Waxman, David J
R01ES024421 Elife (2018 05 14) 29757144
2018
Configurational and Conformational Equilibria ofN6-(2-Deoxy-d-erythro-pentofuranosyl)-2,6-diamino-3...
Bamberger, StephanieN; Malik, Chanchal K;Voehler, Markus W;Brown, Summer K;Pan, Hope; Johns ...
R01ES029357,T32ES007028
Chem Res Toxicol (201809 17)
30169026
2018
Corrigendum: 5-Formylcytosine mediatedDNA-protein cross-links block DNA replication andinduce muta ...
Ji, Shaofei; Fu, Iwen;Naldiga, Spandana;Shao, Hongzhao; Basu,Ashis K; Broyde, Suse;Tretyak ...
R01ES025987 Nucleic Acids Res (201810 12)
30184121
2018
Crosstalk of Genetic Variants, Allele-Specific DNAMethylation, and Environmental Factors for Comple ...
Wang, Huishan; Lou,Dan; Wang, Zhibin
R01ES025761,R01ES025761,U01ES026721
Front Genet (2018) 30687383
2018
Cytotoxic and mutagenic properties of alkylphosphotriester lesions in Escherichia coli cells.
Wu, Jiabin; Wang,Pengcheng; Wang,Yinsheng
R01ES025121 Nucleic Acids Res (201805 04)
29514270
2018
Cytotoxic and mutagenic properties of minor-grooveO2-alkylthymidine lesions in human cells.
Wu, Jun; Wang,Pengcheng; Li, Lin;You, Changjun; Wang,Yinsheng
R01ES025121 J Biol Chem (2018 06 01) 29685891
2018
Cytotoxic and mutagenic properties ofO6-alkyl-2'-deoxyguanosine lesions in Escherichia colicells.
Wang, Pengcheng;Wang, Yinsheng
R01ES025121 J Biol Chem (2018 09 28) 30068548
2018
Determination of thiocyanate in exhaled breathcondensate.
Chandler, Joshua D;Horati, Hamed; Walker,Douglas I; Pagliano,Enea; Tirouvanziam,Rabindra; V ...
P30ES019776,R01ES023485,U2CES026560
Free Radic Biol Med (201810)
30144632
2018
Disulfiram combats cancer via cripplingvalosin-containing protein/p97 segregase adaptorNPL4.
Ding, Nan; Zhu,Qianzheng
R01ES012991 Transl Cancer Res (2018Apr)
30112292
2018
DNA Damage, Mutagenesis and Cancer. Basu, Ashis K R01ES023350 Int J Mol Sci (2018 Mar23)
29570697
2018
DNA polymerase beta participates in DNAEnd-joining.
Ray, Sreerupa; Breuer,Gregory; DeVeaux,Michelle; Zelterman,Daniel; Bindra, Ranjit;Sweasy, ...
R01ES019179 Nucleic Acids Res (201801 09)
29161447
2018
Early life Triclosan exposure and child adiposity at8 Years of age: a prospective cohort study.
Kalloo, Geetika;Calafat, Antonia M;Chen, Aimin; Yolton,Kimberly; Lanphear,Bruce P; Braun, ...
R01ES025214 Environ Health (2018 0305)
29506550
2018
Effect of frozen/thawed embryo transfer onbirthweight, macrosomia, and low birthweight ratesin US ...
Litzky, Julia F; Boulet,Sheree L; Esfandiari,Navid; Zhang, Yujia;Kissin, Dmitry M;Theiler, ...
P01ES022832,P30ES019776,R01ES025145,R01ES025145,R24ES028507
Am J Obstet Gynecol(2018 04)
29291410
2018
Effects of Cadmium Exposure on DNA Methylation atImprinting Control Regions and Genome-Wide inMoth ...
Cowley, Michael;Skaar, David A; Jima,Dereje D; Maguire,Rachel L; Hudson,Kathleen M; Park, ...
K22ES027510,P30ES025128
Environ Health Perspect(2018 03 08)
29529597
2018
Effects of Perinatal Exposure to Dibutyltin Chloride onFat and Glucose Metabolism in Mice, and Mole ...
Chamorro-García,Raquel; Shoucri,Bassem M; Willner,Sigal; Käch, Heidi;Janesick, Amanda;Blum ...
R01ES023316,R01ES023316
Environ Health Perspect(2018 05)
29787037
2018
Electron-Mediated Aminyl and Iminyl Radicals fromC5 Azido-Modified Pyrimidine Nucleosides AugmentR ...
Wen, Zhiwei; Peng,Jufang; Tuttle, PalomaR; Ren, Yaou; Garcia,Carol; Debnath, Dipra;Rishi, ...
R01ES005775,R01ES023569
Org Lett (2018 12 07) 30457873
2018
Endocrine disruptor exposure during developmentincreases incidence of uterine fibroids by altering ...
Prusinski Fernung,Lauren E; Yang, Qiwei;Sakamuro, Daitoku;Kumari, Alpana; Mas,Aymara; Al-He ...
R01ES028615 Biol Reprod (2018 10 01) 29688260
2018
Endocrine Disruptors and Developmental Origins ofNonalcoholic Fatty Liver Disease.
Treviño, Lindsey S;Katz, Tiffany A
U01ES026719 Endocrinology (2018 0101)
29126168
2018
Enhanced spontaneous DNA twisting/bendingfluctuations unveiled by fluorescence lifetimedistributio ...
Chakraborty, Sagnik;Steinbach, Peter J; Paul,Debamita; Mu, Hong;Broyde, Suse; Min,Jung-Hyu ...
R01ES025987 Nucleic Acids Res (201802 16)
29267981
2018
Environmentally Induced Epigenetic Plasticity inDevelopment: Epigenetic Toxicity and Epigenetic Ada...
Tian, Fu-Ying; Marsit,Carmen J
P01ES022832,P30ES019776,R01ES025145,R01ES025145,R24ES028507
Curr Epidemiol Rep (2018Dec)
30984515
2018
Environmentally induced epigenetic transgenerationalinheritance of disease.
Nilsson, Eric E;Sadler-Riggleman,Ingrid; Skinner,Michael K
R01ES012974,R01ES012974
Environ Epigenet (2018Apr)
30038800
2018
Epigenetic mechanisms in the placenta related to infantneurodevelopment.
Lester, Barry M;Marsit, Carmen J
P01ES022832,R01ES025145,R01ES025145,R24ES028507
Epigenomics (2018 03 01) 29381081
2018
Epigenetic Transgenerational Inheritance of AlteredSperm Histone Retention Sites.
Ben Maamar, Millissia;Sadler-Riggleman,Ingrid; Beck, Daniel;Skinner, Michael K
R01ES012974,R01ES012974
Sci Rep (2018 03 28) 29593303
2018
Evidence that microplastics aggravate the toxicity oforganophosphorus flame retardants in mice (Mus ...
Deng, Yongfeng;Zhang, Yan; Qiao,Ruxia; Bonilla, MelvinM; Yang, Xiaoliang;Ren, Hongqiang; L ...
R01ES027981 J Hazard Mater (2018 0905)
29908513
2018
Expanding upon the Human Myometrial Stem CellHypothesis and the Role of Race, Hormones, Age, andPa ...
Prusinski Fernung,Lauren E; Jones,Kimya; Mas, Aymara;Kleven, Daniel; Waller,Jennifer L; Al- ...
R01ES028615 Am J Pathol (2018 10) 30075150
2018
Explosive mutation accumulation triggered byheterozygous human Pol ε proofreading-deficiency isdri ...
Hodel, Karl P; de Borja,Richard; Henninger,Erin E; Campbell,Brittany B; Ungerleider,Nathan; ...
R01ES028271 Elife (2018 02 28) 29488881
2018
Extracellular vesicle-enriched microRNAs interact inthe association between long-term particulate m ...
Rodosthenous,Rodosthenis S; Kloog,Itai; Colicino, Elena;Zhong, Jia; Herrera,Luis A; Vokonas ...
P30ES009089,P30ES023515,R01ES027747
Environ Res (2018 11) 30216846
2018
Functional Analysis of Cancer-Associated DNAPolymerase ε Variants in Saccharomyces cerevisiae.
Barbari, Stephanie R;Kane, Daniel P; Moore,Elizabeth A;Shcherbakova, Polina V
R01ES015869 G3 (Bethesda) (2018 0302)
29352080
2018
Genetic control of predominantly error-free replicationthrough an acrolein-derived minor-groove DNA ...
Yoon, Jung-Hoon;Hodge, Richard P;Hackfeld, Linda C;Park, Jeseong; RoyChoudhury, Jayati; Pra...
R01ES022948 J Biol Chem (2018 02 23) 29330301
2018
Genome-wide association study identifies a novellocus for cannabis dependence.
Agrawal, A; Chou, Y-L;Carey, C E; Baranger, DA A; Zhang, B; Sherva,R; Wetherill, L; Kapoor...
U24ES026699 Mol Psychiatry (2018 05) 29112194
2018
Genome-wide association study of telomere lengthamong South Asians identifies a second RTEL1 associ...
Delgado, Dayana A;Zhang, Chenan; Chen,Lin S; Gao, Jianjun;Roy, Shantanu; Shinkle,Justin; S ...
P30ES027792,P42ES010349,R35ES028379
J Med Genet (2018 01) 29151059
2018
Genome-wide DNA methylation profiling of primarycolorectal laterally spreading tumors identifies di ...
Zhu, Liangliang; Yan,Feihu; Wang, Zhen;Dong, Haiyan; Bian,Chengling; Wang, Ting;Yu, Enda; ...
U24ES026699 Int J Cancer (2018 11 15) 30183087
2018
Genome-wide excision repair in Arabidopsis iscoupled to transcription and reflects circadian gene e ...
Oztas, Onur; Selby,Christopher P; Sancar,Aziz; Adebali, Ogun
P30ES010126,R01ES027255
Nat Commun (2018 04 17) 29666379
2018
High-throughput inference of pairwise coalescencetimes identifies signals of selection and enriched ...
Palamara, PierFrancesco; Terhorst,Jonathan; Song, Yun S;Price, Alkes L
R03ES027902 Nat Genet (2018 09) 30104759
2018
Histone Modifications: Epigenetic Mediators ofEnvironmental Exposure Memory.
Camacho, Jessica;Allard, Patrick
R01ES027487,R01ES027487
Epigenet Insights (2018) 30443644
2018
Histone tails decrease N7-methyl-2'-deoxyguanosinedepurination and yield DNA-protein cross-links in ...
Yang, Kun; Park,Daeyoon; Tretyakova,Natalia Y; Greenberg,Marc M
R01ES023350 Proc Natl Acad Sci U S A(2018 11 27)
30429328
2018
Hypoxia Promotes Resistance to EGFR Inhibition inNSCLC Cells via the Histone Demethylases, LSD1and ...
Lu, Yuhong; Liu,Yanfeng; Oeck,Sebastian; Glazer, PeterM
R01ES005775 Mol Cancer Res (2018 10) 29934325
2018
Identification of ATIC as a Novel Target forChemoradiosensitization.
Liu, Xiangfei; Paila,Uma Devi; Teraoka,Sharon N; Wright,Jocyndra A; Huang,Xin; Quinlan, Aa ...
R01ES027121 Int J Radiat Oncol BiolPhys (2018 01 01)
29029884
2018
Identification of YTH Domain-Containing Proteins asthe Readers for N1-Methyladenosine in RNA.
Dai, Xiaoxia; Wang,Tianlu; Gonzalez,Gwendolyn; Wang,Yinsheng
R01ES025121,T32ES018827
Anal Chem (2018 06 05) 29791134
2018
Impact of CAR Agonist Ligand TCPOBOP on MouseLiver Chromatin Accessibility.
Lodato, Nicholas J;Rampersaud, Andy;Waxman, David J
R01ES024421 Toxicol Sci (2018 07 01) 29617930
2018
Impact of Early-Life Weight Status on CognitiveAbilities in Children.
Li, Nan; Yolton,Kimberly; Lanphear,Bruce P; Chen, Aimin;Kalkwarf, Heidi J;Braun, Joseph M
R01ES025214 Obesity (Silver Spring)(2018 06)
29797555
2018
Impact of prenatal arsenic exposure on chronic adultdiseases.
Young, Jamie L; Cai,Lu; States, JChristopher
R01ES027778,T32ES011564
Syst Biol Reprod Med(2018 Dec)
29873257
2018
Impact of tobacco-specific nitrosamine-derived DNAadducts on the efficiency and fidelity of DNA rep ...
Du, Hua; Leng, Jiapeng;Wang, Pengcheng; Li,Lin; Wang, Yinsheng
R01ES025121 J Biol Chem (2018 07 13) 29789427
2018
Importance of homo-dimerization ofFanconi-associated nuclease 1 in DNA flap cleavage.
Rao, Timsi; Longerich,Simonne; Zhao,Weixing; Aihara,Hideki; Sung, Patrick;Xiong, Yong
R01ES007061 DNA Repair (Amst) (201804)
29518739
2018
In a Class of Its Own: A New Family ofDeubiquitinases Promotes Genome Stability.
Coleman, Kate E;Huang, Tony T
R01ES025166 Mol Cell (2018 04 05) 29625031
2018
Incomplete base excision repair contributes to celldeath from antibiotics and other stresses.
Gruber, Charley C;Walker, Graham C
R35ES028303 DNA Repair (Amst) (201811)
30181041
2018
Inhalational exposure to particulate matter air pollutionalters the composition of the gut microbio ...
Mutlu, Ece A; Comba,Işın Y; Cho, Takugo;Engen, Phillip A;Yazıcı, Cemal;Soberanes, Saul; Ha ...
R01ES015024,U01ES026718
Environ Pollut (2018 Sep) 29783199
2018
Insights into the effect of minor groove interactionsand metal cofactors on mutagenic replication b ...
Koag, Myong-Chul;Lee, Seongmin
R01ES026676 Biochem J (2018 02 09) 29301983
2018
Integrating -Omics Approaches into HumanPopulation-Based Studies of Prenatal and Early-LifeExposur ...
Everson, Todd M;Marsit, Carmen J
P01ES022832,P30ES019776,R01ES025145,R01ES025145,R24ES028507
Curr Environ Health Rep(2018 09)
30054820
2018
Intrauterine multi-metal exposure is associated withreduced fetal growth through modulation of the ...
Deyssenroth, Maya A;Gennings, Chris; Liu,Shelley H; Peng,Shouneng; Hao, Ke;Lambertini, Luc ...
P01ES022832,P30ES023515,P42ES007373,R01ES025145,R01ES025145,R24ES028507
Environ Int (2018 11) 30125854
2018
Introduction to the Thematic Minireview Series: DNAdouble-strand break repair and pathway choice.
Sung, Patrick R01ES007061 J Biol Chem (2018 07 06) 29853635
2018
Krebs-cycle-deficient hereditary cancer syndromes aredefined by defects in homologous-recombination ...
Sulkowski, Parker L;Sundaram, Ranjini K;Oeck, Sebastian; Corso,Christopher D; Liu,Yanfeng; ...
R01ES005775 Nat Genet (2018 08) 30013182
2018
Lesion Sensing during Initial Binding by YeastXPC/Rad4: Toward Predicting Resistance toNucleotide ...
Mu, Hong; Zhang,Yingkai; Geacintov,Nicholas E; Broyde,Suse
R01ES025987 Chem Res Toxicol (201811 19)
30284444
2018
Long repeating (TTAGGG) n single-stranded DNAself-condenses i ...
Kar, Anirban; Jones,Nathan; Arat, N Özlem;Fishel, Richard;Griffith, Jack D
R56ES013773 J Biol Chem (2018 06 15) 29674319
2018
Long-Term In Vitro Expansion of Epithelial StemCells Enabled by Pharmacological Inhibition ofPAK1- ...
Zhang, Chengkang;Lee, Hyung Joo;Shrivastava, Anura;Wang, Ruipeng;McQuiston, Travis J;Chall ...
U24ES026699 Cell Rep (2018 10 16) 30332641
2018
Loss of E2F7 confers resistance to poly-ADP-ribosepolymerase (PARP) inhibitors in BRCA2-deficient c...
Clements, Kristen E;Thakar, Tanay; Nicolae,Claudia M; Liang,Xinwen; Wang,Hong-Gang; Moldova...
R01ES026184 Nucleic Acids Res (201809 28)
30032296
2018
Mapping-free variant calling using haplotypereconstruction from k-mer frequencies.
Audano, Peter A;Ravishankar,Shashidhar; Vannberg,Fredrik O
R01ES026243 Bioinformatics (2018 0515)
29186321
2018
Meiosis-specific recombinase Dmc1 is a potentinhibitor of the Srs2 antirecombinase.
Crickard, J Brooks;Kaniecki, Kyle; Kwon,Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 Proc Natl Acad Sci U S A(2018 10 23)
30301803
2018
miRNA expression profiles of premalignant andmalignant arsenic-induced skin lesions.
Al-Eryani, Laila;Jenkins, Samantha F;States, Vanessa A; Pan,Jianmin; Malone, JanineC; Rai, ...
R01ES027778,T35ES014559
PLoS One (2018) 30114287
2018
Mitochondrial network responses in oxidativephysiology and disease.
Go, Young-Mi;Fernandes, Jolyn; Hu,Xin; Uppal, Karan;Jones, Dean P
P30ES019776,R01ES023485
Free Radic Biol Med (201802 20)
29317273
2018
Modification of Wnt signaling pathway onparaquat-induced inhibition of neural progenitor cellproli ...
Zhao, Lina; Yan,Mengling; Wang,Xinjin; Xiong, Guiya;Wu, Chunhua; Wang,Zhibin; Zhou, Zhiju ...
R01ES025761,R01ES025761,U01ES026721
Food Chem Toxicol (2018Nov)
30171970
2018
Molecular basis for damage recognition andverification by XPC-RAD23B and TFIIH in nucleotideexcisi ...
Mu, Hong; Geacintov,Nicholas E; Broyde,Suse; Yeo, Jung-Eun;Schärer, Orlando D
R01ES025987 DNA Repair (Amst) (201811)
30174301
2018
Monoubiquitinated γ-H2AX: Abundant product andspecific biomarker for non-apoptotic DNAdouble-stran ...
Luczak, Michal W;Zhitkovich, Anatoly
R01ES008786,R01ES028072
Toxicol Appl Pharmacol(2018 09 15)
30006243
2018
Mutant FUS causes DNA ligation defects to inhibitoxidative damage repair in Amyotrophic Lateral Scl ...
Wang, Haibo; Guo,Wenting; Mitra, Joy;Hegde, Pavana M;Vandoorne, Tijs;Eckelmann, Bradley J;...
R01ES012512 Nat Commun (2018 09 11) 30206235
2018
Mutation of hop-1 and pink-1 attenuates vulnerabilityof neurotoxicity in C. elegans: the role of mi ...
Wu, Siyu; Lei, Lili;Song, Yang; Liu,Mengting; Lu, Shibo;Lou, Dan; Shi,Yonghong; Wang, Zh ...
R01ES025761,R01ES025761,U01ES026721
Exp Neurol (2018 11) 30076829
2018
Myeloperoxidase oxidation of methionine associateswith early cystic fibrosis lung disease.
Chandler, Joshua D;Margaroli, Camilla;Horati, Hamed; Kilgore,Matthew B; Veltman,Mieke; Liu, ...
P30ES019776,R01ES023485
Eur Respir J (2018 10) 30190273
2018
Nickel exposure induces persistent mesenchymalphenotype in human lung epithelial cells through epig...
Jose, Cynthia C;Jagannathan,Lakshmanan; Tanwar,Vinay S; Zhang,Xiaoru; Zang,Chongzhi; Cudda ...
P30ES000260,R01ES024727
Mol Carcinog (2018 06) 29528143
2018
Normalized Retention Time for Targeted Analysis ofthe DNA Adductome.
Cui, Yuxiang; Wang,Pengcheng; Yu, Yang;Yuan, Jun; Wang,Yinsheng
R01ES029749 Anal Chem (2018 12 18) 30500177
2018
Not just heads and tails: The complexity of the spermepigenome.
Gold, Hannah B; Jung,Yoon Hee; Corces,Victor G
R01ES027859,R01ES027859
J Biol Chem (2018 09 07) 29507096
2018
Nucleosome positions establish an extended mutationsignature in melanoma.
Brown, Alexander J;Mao, Peng; Smerdon,Michael J; Wyrick, JohnJ; Roberts, Steven A
R01ES028698 PLoS Genet (2018 11) 30485262
2018
Oxidative stress predicts cognitive decline with agingin healthy adults: an observational study.
Hajjar, Ihab; Hayek,Salim S; Goldstein,Felicia C; Martin, Greg;Jones, Dean P;Quyyumi, Arsh ...
P30ES019776,R01ES023485
J Neuroinflammation(2018 Jan 16)
29338747
2018
PARP10 promotes cellular proliferation andtumorigenesis by alleviating replication stress.
Schleicher, Emily M;Galvan, Adri M;Imamura-Kawasawa,Yuka; Moldovan,George-Lucian;Nicolae, ...
R01ES026184 Nucleic Acids Res (201809 28)
30032250
2018
Particulate Matter Air Pollution: Effects on theCardiovascular System.
Hamanaka, Robert B;Mutlu, Gökhan M
P30ES027792,R01ES015024,U01ES026718
Front Endocrinol(Lausanne) (2018)
30505291
2018
Patterns of early life body mass index and childhoodoverweight and obesity status at eight years of ...
Braun, Joseph M;Kalkwarf, Heidi J;Papandonatos, GeorgeD; Chen, Aimin;Lanphear, Bruce P
R01ES025214 BMC Pediatr (2018 05 11) 29751833
2018
Permissiveness to form pluripotent stem cells may bean evolutionarily derived characteristic in Mus ...
Garbutt, Tiffany A;Konneker, Thomas I;Konganti, Kranti;Hillhouse, Andrew E;Swift-Haire, Fra ...
P42ES027704,U01ES026717
Sci Rep (2018 10 02) 30279419
2018
Population-based dose-response analysis of livertranscriptional response to trichloroethylene in mo ...
Venkatratnam,Abhishek; House, JohnS; Konganti, Kranti;McKenney, Connor;Threadgill, David W; ...
P30ES025128,P42ES027704,U01ES026717
Mamm Genome (2018Feb)
29353386
2018
Preconception cold-induced epigenetic inheritance. Skinner, Michael K R01ES012974,R01ES012974
Nat Med (2018 09) 30194411
2018
Prenatal Exposure to Bisphenol A Disrupts NaturallyOccurring Bimodal DNA Methylation at Proximal Pr...
Taylor, Julia A; Shioda,Keiko; Mitsunaga,Shino; Yawata, Shiomi;Angle, Brittany M;Nagel, Su ...
R01ES023316,R01ES023316
Endocrinology (2018 0201)
29220483
2018
Prenatal exposure to perfluoroalkyl substances andadipocytokines: the HOME Study.
Buck, Catherine O;Eliot, Melissa N;Kelsey, Karl T; Calafat,Antonia M; Chen,Aimin; Ehrlich, ...
R01ES025214 Pediatr Res (2018 12) 30250302
2018
Prenatal Exposure to Perfluoroalkyl Substances: InfantBirth Weight and Early Life Growth.
Shoaff, Jessica;Papandonatos, GeorgeD; Calafat, Antonia M;Chen, Aimin; Lanphear,Bruce P; Eh ...
R01ES025214 Environ Epidemiol (2018Jun)
30272047
2018
Prenatal influences on temperament development: Therole of environmental epigenetics.
Gartstein, Maria A;Skinner, Michael K
R01ES012974,R01ES012974
Dev Psychopathol (201810)
29229018
2018
PTEN Regulates Nonhomologous End Joining ByEpigenetic Induction of NHEJ1/XLF.
Sulkowski, Parker L;Scanlon, Susan E; Oeck,Sebastian; Glazer, PeterM
R01ES005775 Mol Cancer Res (2018 08) 29739874
2018
Putrescine as indicator of manganese neurotoxicity:Dose-response study in human SH-SY5Y cells.
Fernandes, Jolyn;Chandler, Joshua D;Liu, Ken H; Uppal,Karan; Go, Young-Mi;Jones, Dean P
P30ES019776,R01ES023485
Food Chem Toxicol (2018Jun)
29684492
2018
Pyrimidine Nucleosides with a Reactive(β-Chlorovinyl)sulfone or (β-Keto)sulfone Group atthe C5 Pos ...
Suzol, Sazzad H;Howlader, A Hasan;Wen, Zhiwei; Ren,Yaou; Laverde,Eduardo E; Garcia,Carol; ...
R01ES023569 ACS Omega (2018 Apr 30) 29732453
2018
Rapid onset of multiple concurrent squamous cellcarcinomas associated with the use of an arsenic-co ...
Siefring, Mark Louis;Lu, Doanh; States, JChristopher; VanHoang, Minh
R01ES027778 BMJ Case Rep (2018 Mar30)
29602886
2018
RE: "INVITED COMMENTARY: EXPOSUREBIOMARKERS INDICATE MORE THAN JUSTEXPOSURE".
Braun, Joseph M R01ES025214 Am J Epidemiol (2018 0401)
29351641
2018
Redox Equivalents and Mitochondrial Bioenergetics. Roede, James R; Go,Young-Mi; Jones, DeanP
R01ES023485,T32ES012870
Methods Mol Biol (2018) 29851002
2018
Regulation of Hed1 and Rad54 binding duringmaturation of the meiosis-specific presynapticcomplex.
Crickard, J Brooks;Kaniecki, Kyle; Kwon,YoungHo; Sung,Patrick; Lisby, Michael;Greene, Eric ...
R01ES007061 EMBO J (2018 04 03) 29444896
2018
Reorientation of the Methyl Group in MAs(III) is theRate-Limiting Step in the ArsM As(III) S-Adenos ...
Packianathan, Charles;Li, Jiaojiao; Kandavelu,Palani; Sankaran,Banumathi; Rosen,Barry P
R01ES023779 ACS Omega (2018 Mar) 29600290
2018
Repair of DNA double-strand breaks by mammalianalternative end-joining pathways.
Sallmyr, Annahita;Tomkinson, Alan E
R01ES012512 J Biol Chem (2018 07 06) 29530982
2018
Retinoid X Receptor Activation During Adipogenesisof Female Mesenchymal Stem Cells Programs a Dysfu...
Shoucri, Bassem M;Hung, Victor T;Chamorro-García,Raquel; Shioda, Toshi;Blumberg, Bruce
R01ES023316,R01ES023316
Endocrinology (2018 0801)
29860300
2018
Rev7 dimerization is important for assembly andfunction of the Rev1/Polζ translesion synthesis comp ...
Rizzo, Alessandro A;Vassel, Faye-Marie;Chatterjee, Nimrat;D'Souza, Sanjay; Li,Yunfeng; Hao, ...
P30ES002109,R35ES028303
Proc Natl Acad Sci U S A(2018 08 28)
30111544
2018
RNA polymerase II is released from the DNA templateduring transcription-coupled repair in mammalian ...
Chiou, Yi-Ying; Hu,Jinchuan; Sancar, Aziz;Selby, Christopher P
R01ES027255 J Biol Chem (2018 02 16) 29282293
2018
Roadmap for investigating epigenome deregulationand environmental origins of cancer.
Herceg, Zdenko;Ghantous, Akram;Wild, Christopher P;Sklias, Athena; Casati,Lavinia; Duthie, ...
P30ES010126,R01ES025145,R01ES025145,R24ES028507
Int J Cancer (2018 03 01) 28836271
2018
Role of DNA methylation in altered gene expressionpatterns in adult zebrafish (Danio rerio) exposed ...
Aluru, Neelakanteswar;Karchner, Sibel I;Krick, Keegan S; Zhu,Wei; Liu, Jiang
R01ES024915,R01ES024915
Environ Epigenet (2018Jan)
29686887
2018
S-Nitrosoglutathione Reductase Is Essential forProtecting the Female Heart FromIschemia-Reperfusio ...
Casin, Kevin M;Fallica, Jonathan;Mackowski, Nathan;Veenema, Ryne J; Chan,Ashley; St Paul, ...
T32ES007141,U01ES026721
Circ Res (2018 11 09) 30571462
2018
Screening for gene-environment (G×E) interactionusing omics data from exposed individuals: an appli ...
Argos, Maria; Tong,Lin; Roy, Shantanu;Sabarinathan, Mekala;Ahmed, Alauddin;Islam, Md Tariq ...
P30ES009089,P30ES027792,P42ES010349,R35ES028379
Mamm Genome (2018 02) 29453499
2018
Selective inhibition of CTCF binding by iAs directsTET-mediated reprogramming of 5-hydroxymethylati...
Rea, Matthew;Gripshover, Tyler;Fondufe-Mittendorf,Yvonne
R01ES024478,R25ES027684
Toxicol Appl Pharmacol(2018 01 01)
29175454
2018
Selenium at the redox interface of the genome,metabolome and exposome.
Fernandes, Jolyn; Hu,Xin; Ryan Smith, M;Go, Young-Mi; Jones,Dean P
R01ES023485 Free Radic Biol Med (201811 01)
29883789
2018
Selenium Supplementation Alters Hepatic Energy andFatty Acid Metabolism in Mice.
Hu, Xin; Chandler,Joshua D; Orr, MichaelL; Hao, Li; Liu, Ken;Uppal, Karan; Go,Young-Mi; J ...
P30ES019776,R01ES023485
J Nutr (2018 05 01) 29982657
2018
Selenium supplementation prevents metabolic andtranscriptomic responses to cadmium in mouse lung.
Hu, Xin; Chandler,Joshua D; Fernandes,Jolyn; Orr, Michael L;Hao, Li; Uppal, Karan;Neujahr, ...
P30ES019776,R01ES023485
Biochim Biophys Acta GenSubj (2018 Nov)
29656123
2018
Sex-Dependent Effects of the Histone DeacetylaseInhibitor, Sodium Valproate, on Reversal Learning A...
Tyler, Christina RSteadman; Smoake,Jane J W; Solomon,Elizabeth R; Villicana,Estrella; Caldwe ...
R01ES019583 Front Genet (2018) 29963072
2018
Single-nucleotide resolution dynamic repair maps ofUV damage in Saccharomyces cerevisiae genome.
Li, Wentao; Adebali,Ogun; Yang, Yanyan;Selby, Christopher P;Sancar, Aziz
P30ES010126,R01ES027255
Proc Natl Acad Sci U S A(2018 04 10)
29581276
2018
Site-specific cross-linking of proteins to DNA via anew bioorthogonal approach employing oxime liga ...
Pujari, Suresh S; Zhang,Yi; Ji, Shaofei;Distefano, Mark D;Tretyakova, Natalia Y
R01ES023350 Chem Commun (Camb)(2018 Jun 14)
29851420
2018
Smoking gun for a rare mutation mechanism. Goodman, Myron F R35ES028343 Nature (2018 02 08) 29420502
2018 Sodium arsenite exposure inhibits histoneacetyltransferase p300 for attenuating H3K27ac atenhancer ...
Zhu, Yan; Li,Yanqiang; Lou, Dan;Gao, Yang; Yu, Jing;Kong, Dehui; Zhang,Qiang; Jia, Yanka ...
R01ES025761,R01ES025761,U01ES026721
Toxicol Appl Pharmacol(2018 10 15)
30130555
2018
Soluble inflammatory mediators induce transcriptionalre-organization that is independent of dna met ...
Jiang, Kaiyu; Wong,Laiping; Chen, Yanmin;Xing, Xiaoyun; Li,Daofeng; Wang, Ting;Jarvis, Ja ...
U24ES026699 J Reprod Immunol (201808)
29800761
2018
Spontaneous self-segregation of Rad51 and Dmc1DNA recombinases within mixed recombinasefilaments.
Crickard, J Brooks;Kaniecki, Kyle; Kwon,YoungHo; Sung,Patrick; Greene, Eric C
R01ES007061 J Biol Chem (2018 03 16) 29382724
2018
Stochastic Endogenous Replication Stress CausesATR-Triggered Fluctuations in CDK2 Activity thatDyn ...
Daigh, Leighton H; Liu,Chad; Chung, Mingyu;Cimprich, Karlene A;Meyer, Tobias
R01ES016486 Cell Syst (2018 07 25) 29909278
2018
Structural and Kinetic Studies of the Effect of GuanineN7 Alkylation and Metal Cofactors on DNA Rep ...
Kou, Yi; Koag,Myong-Chul; Lee,Seongmin
R01ES026676 Biochemistry (2018 08 28) 29957995
2018
Successes and failures of uterine leiomyoma drugdiscovery.
Ali, Mohamed;Chaudhry, ZunirTayyeb; Al-Hendy,Ayman
R01ES028615 Expert Opin Drug Discov(2018 02)
29254389
2018
Suppression of homology-dependent DNAdouble-strand break repair induces PARP inhibitorsensitivity ...
Scanlon, Susan E;Hegan, Denise C;Sulkowski, Parker L;Glazer, Peter M
R01ES005775 Oncotarget (2018 Jan 12) 29435132
2018
Synergistic effects of H3 and H4 nucleosome tails onstructure and dynamics of a lesion-containing D ...
Cai, Yuqin; Fu, Iwen;Geacintov, Nicholas E;Zhang, Yingkai;Broyde, Suse
R01ES025987 DNA Repair (Amst) (201805)
29631253
2018
Technical adequacy of bisulfite sequencing andpyrosequencing for detection of mitochondrial DNAmet ...
Owa, Chie; Poulin,Matthew; Yan, Liying;Shioda, Toshi
R01ES023316,R01ES023316
PLoS One (2018) 29420656
2018
The 3D Genome Browser: a web-based browser forvisualizing 3D genome organization and long-rangechr ...
Wang, Yanli; Song,Fan; Zhang, Bo; Zhang,Lijun; Xu, Jie; Kuang,Da; Li, Daofeng;Choudhary, ...
U24ES026699 Genome Biol (2018 10 04) 30286773
2018
The association of traffic-related air and noisepollution with maternal blood pressure and hyperten ...
Sears, Clara G; Braun,Joseph M; Ryan,Patrick H; Xu,Yingying; Werner,Erika F; Lanphear, Bru...
P42ES013660,R01ES025214
Environ Int (2018 12) 30300815
2018
The COP9 signalosome inhibits Cullin-RING E3ubiquitin ligases independently of its deneddylase acti...
Suisse, Annabelle;Békés, Miklós; Huang,Tony T; Treisman,Jessica E
R01ES025166 Fly (Austin) (2018) 29355077
2018
The deoxyribose phosphate lyase of DNA polymeraseβ suppresses a processive DNA synthesis to prevent ...
Lai, Yanhao;Weizmann, Yossi; Liu,Yuan
R01ES023569 Nucleic Acids Res (201809 28)
30085293
2018
The Emerging Role of p27 in Development ofDiseases.
Yang, Qiwei;Al-Hendy, Ayman
R01ES028615 Cancer Stud Mol Med(2018 Nov)
30474063
2018
The emerging spectrum of early life exposure-relatedinflammation and epigenetic therapy.
Yang, Qiwei; Ali,Mohamed; ElAndaloussi, Abdeljabar;Al-Hendy, Ayman
R01ES028615 Cancer Stud Mol Med(2018 Nov)
30474062
2018
The hypoxic tumor microenvironment in vivo selectsthe cancer stem cell fate of breast cancer cells.
Kim, Hoon; Lin, Qun;Glazer, Peter M; Yun,Zhong
R01ES005775 Breast Cancer Res (201803 06)
29510720
2018
The Memory of Environmental Chemical Exposure inC. elegans Is Dependent on the Jumonji Demethylases...
Camacho, Jessica;Truong, Lisa; Kurt,Zeyneb; Chen,Yen-Wei; Morselli,Marco; Gutierrez, Gerar...
R01ES027487,R01ES027487,R25ES025507
Cell Rep (2018 05 22) 29791850
2018
The NIEHS TaRGET II Consortium andenvironmental epigenomics.
Wang, Ting; Pehrsson,Erica C; Purushotham,Deepak; Li, Daofeng;Zhuo, Xiaoyu; Zhang,Bo; Laws ...
P30ES013508,P30ES017885,P30ES025128,R01ES028802,R01ES028802,R01ES028802,R01ES028802,U01ES026697,U01ES026717,U01ES026719,U24ES026699
Nat Biotechnol (2018 0306)
29509741
2018
The ontogeny of myometrial stem cells in OCT4-GFPtransgenic mouse model.
Brakta, Soumia; Mas,Aymara; Al-Hendy,Ayman
R01ES028615 Stem Cell Res Ther (201811 29)
30486855
2018
The Structure of an As(III) S-AdenosylmethionineMethyltransferase with 3-Coordinately Bound As(III)...
Packianathan, Charles;Kandavelu, Palani;Rosen, Barry P
R01ES023779 Biochemistry (2018 07 17) 29894638
2018
Thiolation in arsenic metabolism: a chemicalperspective.
Fan, Changjun; Liu,Guangliang; Long,Yanmin; Rosen, Barry;Cai, Yong
R01ES023779 Metallomics (2018 10 17) 30207373
2018
Toxicological Antagonism among Welding FumeMetals: Inactivation of Soluble Cr(VI) by Iron.
Krawic, Casey;Zhitkovich, Anatoly
R01ES008786,R01ES028072
Chem Res Toxicol (201811 19)
30362728
2018
Translesion polymerase kappa-dependent DNAsynthesis underlies replication fork recovery.
Tonzi, Peter; Yin,Yandong; Lee, ChelseaWei Ting; Rothenberg,Eli; Huang, Tony T
R01ES025166 Elife (2018 11 13) 30422114
2018
Transposable Element Mediated Innovation in GeneRegulatory Landscapes of Cells: Re-Visiting the "Ge ...
Sundaram, Vasavi;Wang, Ting
U24ES026699 Bioessays (2018 Jan) 29206283
2018
Upregulation of histone-lysine methyltransferasesplays a causal role in hexavalent chromium-induced ...
Wang, Zhishan; Wu,Jianjun; Humphries,Brock; Kondo, Kazuya;Jiang, Yiguo; Shi,Xianglin; Yang ...
P30ES026529,R01ES026151
Toxicol Appl Pharmacol(2018 03 01)
29391238
2018
Variability and predictors of serum perfluoroalkylsubstance concentrations during pregnancy and ear ...
Kingsley, Samantha L;Eliot, Melissa N;Kelsey, Karl T; Calafat,Antonia M; Ehrlich,Shelley; L ...
R01ES025214 Environ Res (2018 08) 29734025
2018
What is the potential of nanolock- andnanocross-nanopore technology in cancer diagnosis?
Gu, Li-Qun; Gates,Kent S; Wang, MichaelX; Li, Guangfu
R01ES021007 Expert Rev Mol Diagn(2018 02)
29171309
2018
xMWAS: a data-driven integration and differentialnetwork analysis tool.
Uppal, Karan; Ma,Chunyu; Go,Young-Mi; Jones, DeanP; Wren, Jonathan
P30ES019776,R01ES023485
Bioinformatics (2018 0215)
29069296
2018
2-Hydroxyglutarate produced by neomorphic IDHmutations suppresses homologous recombination andindu ...
Sulkowski, Parker L;Corso, Christopher D;Robinson, Nathaniel D;Scanlon, Susan E;Purshouse, ...
R01ES005775 Sci Transl Med (2017 0201)
28148839
2017
A comparison of nucleosome organization inDrosophila cell lines.
Martin, Rebecca L;Maiorano, John; Beitel,Greg J; Marko, John F;McVicker, Graham;Fondufe-Mit ...
R01ES024478 PLoS One (2017) 28570602
2017
A METHYLATION-TO-EXPRESSION FEATUREMODEL FOR GENERATING ACCURATEPROGNOSTIC RISK SCORES AND IDENTIF ...
Thompson, Jeffrey A;Marsit, Carmen J
P01ES022832,R01ES025145,R01ES025145
Pac Symp Biocomput(2017)
27897002
2017
A novel role of the Dna2 translocase function in DNAbreak resection.
Miller, Adam S; Daley,James M; Pham, NhungTuyet; Niu, Hengyao;Xue, Xiaoyu; Ira,Grzegorz; S ...
R01ES007061 Genes Dev (2017 03 01) 28336516
2017
A parametric model to estimate the proportion fromtrue null using a distribution for p-values.
Yu, Chang; Zelterman,Daniel
R01ES005775 Comput Stat Data Anal(2017 Oct)
28827889
2017
A role for the base excision repair enzyme NEIL3 inreplication-dependent repair of interstrand DNA ...
Yang, Zhiyu; Nejad,Maryam Imani; Varela,Jacqueline Gamboa;Price, Nathan E; Wang,Yinsheng; G ...
R01ES021007,T32ES018827
DNA Repair (Amst) (201704)
28262582
2017
Abasic and oxidized ribonucleotides embedded inDNA are processed by human APE1 and not by RNaseH2.
Malfatti, MatildeClarissa; Balachander,Sathya; Antoniali,Giulia; Koh, KyungDuk; Saint-Pierre ...
R01ES026243 Nucleic Acids Res (2017Nov 02)
28977421
2017
Acetylation Enhances TET2 Function in Protectingagainst Abnormal DNA Methylation during OxidativeS ...
Zhang, Yang W; Wang,Zhihong; Xie, Wenbing;Cai, Yi; Xia, Limin;Easwaran, Hariharan;Luo, Ji ...
R01ES011858 Mol Cell (2017 Jan 19) 28107650
2017
Airborne Particulate Matter Induces NonallergicEosinophilic Sinonasal Inflammation in Mice.
Ramanathan Jr,Murugappan; LondonJr, Nyall R; Tharakan,Anuj; Surya, Nitya;Sussan, Thomas E; ...
U01ES026721 Am J Respir Cell Mol Biol(2017 07)
28245149
2017
Ancestral perinatal obesogen exposure results in atransgenerational thrifty phenotype in mice.
Chamorro-Garcia,Raquel; Diaz-Castillo,Carlos; Shoucri, BassemM; Käch, Heidi;Leavitt, Ron; S ...
R01ES023316,R01ES023316
Nat Commun (2017 12 08) 29222412
2017
Anti-tumor Activity of miniPEG-γ-Modified PNAs toInhibit MicroRNA-210 for Cancer Therapy.
Gupta, Anisha; Quijano,Elias; Liu, Yanfeng;Bahal, Raman; Scanlon,Susan E; Song, Eric;Hsieh ...
R01ES005775 Mol Ther Nucleic Acids(2017 Dec 15)
29246289
2017
ATM, radiation, and the risk of second primary breastcancer.
Bernstein, Jonine L;WECARE StudyCollaborative Group;Concannon, Patrick
R01ES027121 Int J Radiat Biol (2017 10) 28627265
2017
Atrazine induced epigenetic transgenerationalinheritance of disease, lean phenotype and spermepimu ...
McBirney, Margaux;King, Stephanie E;Pappalardo, Michelle;Houser, Elizabeth;Unkefer, Margare ...
R01ES012974,R01ES012974
PLoS One (2017) 28931070
2017
Bacterial resistance to arsenic protects against protistkilling.
Hao, Xiuli; Li, Xuanji;Pal, Chandan; Hobman,Jon; Larsson, D GJoakim; Saquib,Quaiser; Alwat ...
R01ES023779 Biometals (2017 04) 28210928
2017
Bisphenol A in eggs causes development-specific livermolecular reprogramming in two generations of ...
Sadoul, Bastien;Birceanu, Oana; Aluru,Neel; Thomas, Jith K;Vijayan, Mathilakath M
R01ES024915,R01ES024915
Sci Rep (2017 10 26) 29074850
2017
BRCA1-BARD1 promotes RAD51-mediatedhomologous DNA pairing.
Zhao, Weixing;Steinfeld, Justin B;Liang, Fengshan; Chen,Xiaoyong; Maranon,David G; Jian Ma, ...
R01ES007061 Nature (2017 10 19) 28976962
2017
Brevetoxin-2, is a unique inhibitor of the C-terminalredox center of mammalian thioredoxin reductas ...
Chen, Wei; Tuladhar,Anupama; Rolle,Shantelle; Lai, Yanhao;Rodriguez Del Rey,Freddy; Zavala, ...
R01ES023569 Toxicol Appl Pharmacol(2017 08 15)
28551108
2017
Cadmium stimulates myofibroblast differentiation andmouse lung fibrosis.
Hu, Xin; Fernandes,Jolyn; Jones, Dean P;Go, Young-Mi
R01ES023485 Toxicology (2017 05 15) 28341147
2017
Cellular Repair of DNA-DNA Cross-Links Induced by1,2,3,4-Diepoxybutane.
Chesner, Lisa N;Degner, Amanda;Sangaraju, Dewakar;Yomtoubian, Shira;Wickramaratne, Susith;...
R01ES023350 Int J Mol Sci (2017 May18)
28524082
2017
CHD4 Has Oncogenic Functions in Initiating andMaintaining Epigenetic Suppression of MultipleTumor ...
Xia, Limin; Huang,Wenjie; Bellani,Marina; Seidman,Michael M; Wu,Kaichun; Fan, Daiming;Nie ...
R01ES011858 Cancer Cell (2017 05 08) 28486105
2017
Chemical Biology of N5-SubstitutedFormamidopyrimidine DNA Adducts.
Pujari, Suresh S;Tretyakova, Natalia
R01ES023350 Chem Res Toxicol (201701 17)
27959490
2017
Chronic Cigarette Smoke-Induced EpigenomicChanges Precede Sensitization of Bronchial EpithelialCel ...
Vaz, Michelle; Hwang,Stephen Y;Kagiampakis, Ioannis;Phallen, Jillian; Patil,Ashwini; O'Haga ...
R01ES011858 Cancer Cell (2017 09 11) 28898697
2017
Comprehensive Analysis of Hypermutation in HumanCancer.
Campbell, Brittany B;Light, Nicholas;Fabrizio, David;Zatzman, Matthew;Fuligni, Fabio; de Bo ...
R01ES028271 Cell (2017 Nov 16) 29056344
2017
Controlling the Graphene-Bio Interface: Dispersions inAnimal Sera for Enhanced Stability and Reduce ...
Pattammattel, Ajith;Pande, Paritosh;Kuttappan, Deepa;Puglia, Megan; Basu,Ashis K; Amalaradj ...
R01ES023350 Langmuir (2017 12 12) 29144756
2017
Copper-mediated DNA damage by theneurotransmitter dopamine and L-DOPA: Apro-oxidant mechanism.
Rehmani, Nida; Zafar,Atif; Arif, Hussain;Hadi, Sheikh Mumtaz;Wani, Altaf A
R01ES012991 Toxicol In Vitro (2017Apr)
28137434
2017
Correction to: Parma consensus statement onmetabolic disruptors.
Heindel, Jerrold J; VomSaal, Frederick S;Blumberg, Bruce;Bovolin, Patrizia;Calamandrei, Gem ...
R01ES023316,R01ES023316
Environ Health (2017 1206)
29212512
2017
Critical threshold levels of DNA methyltransferase 1are required to maintain DNA methylation across ...
Cai, Yi; Tsai,Hsing-Chen; Yen,Ray-Whay Chiu; Zhang,Yang W; Kong,Xiangqian; Wang, Wei;Xia, ...
R01ES011858 Genome Res (2017 04) 28232479
2017
Cryo-EM structures of human RAD51 recombinasefilaments during catalysis of DNA-strand exchange.
Xu, Jingfei; Zhao,Lingyun; Xu,Yuanyuan; Zhao,Weixing; Sung, Patrick;Wang, Hong-Wei
R01ES007061 Nat Struct Mol Biol (201701)
27941862
2017
Cytotoxic and Mutagenic Properties of C3'-EpimericLesions of 2'-Deoxyribonucleosides in Escherichia ...
Wang, Pengcheng;Amato, Nicholas J;Wang, Yinsheng
R01ES025121,T32ES018827
Biochemistry (2017 07 25) 28650656
2017
Detection of the Excised, Damage-containingOligonucleotide Products of Nucleotide ExcisionRepair i ...
Song, Jimyeong; Kemp,Michael G; Choi,Jun-Hyuk
R01ES027255 Photochem Photobiol(2017 01)
27634428
2017
Differential DNA Methylation Regions in AdultHuman Sperm following Adolescent Chemotherapy:Potenti ...
Shnorhavorian,Margarett; Schwartz,Stephen M; Stansfeld,Barbara;Sadler-Riggleman,Ingrid; Bec ...
R01ES012974,R01ES012974
PLoS One (2017) 28146567
2017
Dissociation of Rad51 Presynaptic Complexes andHeteroduplex DNA Joints by Tandem Assemblies ofSrs2 ...
Kaniecki, Kyle; DeTullio, Luisina; Gibb,Bryan; Kwon,Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 Cell Rep (2017 Dec 12) 29241544
2017
DNA methyltransferase 3b regulates articular cartilagehomeostasis by altering metabolism.
Shen, Jie; Wang,Cuicui; Li, Daofeng;Xu, Taotao; Myers,Jason; Ashton, John M;Wang, Ting; Z ...
U24ES026699 JCI Insight (2017 Jun 15) 28614801
2017
DNA Polymerase Beta Germline Variant ConfersCellular Response to Cisplatin Therapy.
Nemec, Antonia A;Abriola, Laura; Merkel,Jane S; de Stanchina,Elisa; DeVeaux,Michelle; Zelte ...
R01ES019179 Mol Cancer Res (2017 03) 28074003
2017
DNA repair and systemic lupus erythematosus. Meas, Rithy; Burak,Matthew J; Sweasy,Joann B
R01ES019179 DNA Repair (Amst) (201708)
28623091
2017
DNMT and HDAC inhibitors induce cryptictranscription start sites encoded in long terminalrepeats.
Brocks, David;Schmidt, ChristopherR; Daskalakis, Michael;Jang, Hyo Sik; Shah,Nakul M; Li, ...
U24ES026699 Nat Genet (2017 Jul) 28604729
2017
Dynamic maps of UV damage formation and repair forthe human genome.
Hu, Jinchuan; Adebali,Ogun; Adar, Sheera;Sancar, Aziz
P30ES010126,R01ES027255
Proc Natl Acad Sci U S A(2017 06 27)
28607063
2017
Dynamics of p53: A Master Decider of Cell Fate. Luo, Qingyin; Beaver,Jill M; Liu, Yuan;Zhang, Zunzhen
R01ES023569 Genes (Basel) (2017 Feb09)
28208785
2017
Early Life Exposure to Low Levels of AHR AgonistPCB126 (3,3',4,4',5-Pentachlorobiphenyl) Reprograms...
Aluru, Neelakanteswar;Karchner, Sibel I;Glazer, Lilah
R01ES024915,R01ES024915
Toxicol Sci (2017 Dec 01) 28973690
2017
Early-life exposure to EDCs: role in childhood obesityand neurodevelopment.
Braun, Joseph M R01ES025214 Nat Rev Endocrinol (201703)
27857130
2017
Early-Life Phthalate Exposure and Adiposity at 8Years of Age.
Shoaff, Jessica;Papandonatos, GeorgeD; Calafat, Antonia M;Ye, Xiaoyun; Chen,Aimin; Lanphear ...
R01ES025214 Environ Health Perspect(2017 09 11)
28935615
2017
Endocrine Disruptors and Health Effects in Africa: ACall for Action.
Bornman, Maria S;Aneck-Hahn, Natalie H;de Jager, Christiaan;Wagenaar, Gesina M;Bouwman, Hin ...
R01ES023316,R01ES023316
Environ Health Perspect(2017 08 22)
28935616
2017
Endocrine-disrupting chemicals and fatty liver disease.
Foulds, Charles E;Treviño, Lindsey S;York, Brian; Walker,Cheryl L
U01ES026719 Nat Rev Endocrinol (201708)
28524171
2017
Enhancement of BLM-DNA2-Mediated Long-RangeDNA End Resection by CtIP.
Daley, James M;Jimenez-Sainz, Judit;Wang, Weibin; Miller,Adam S; Xue, Xiaoyu;Nguyen, Kevin ...
R01ES007061 Cell Rep (2017 Oct 10) 29020620
2017
EpiCompare: an online tool to define and exploregenomic regions with tissue or cell type-specific e ...
He, Yu; Wang, Ting U24ES026699 Bioinformatics (2017 Oct15)
28605501
2017
Epigenetic effects of environmental chemicals:insights from zebrafish.
Aluru, Neelakanteswar R01ES024915,R01ES024915
Curr Opin Toxicol (2017Oct)
29202112
2017
Epigenetic variation between urban and ruralpopulations of Darwin's finches.
McNew, Sabrina M;Beck, Daniel;Sadler-Riggleman,Ingrid; Knutie, Sarah A;Koop, Jennifer A H; ...
R01ES012974,R01ES012974
BMC Evol Biol (2017 0824)
28835203
2017
Epigenetics and adaptive phenotypic variation betweenhabitats in an asexual snail.
Thorson, Jennifer L M;Smithson, Mark; Beck,Daniel;Sadler-Riggleman,Ingrid; Nilsson, Eric; D...
R01ES012974,R01ES012974
Sci Rep (2017 10 26) 29074962
2017
Epigenomic annotation of noncoding mutationsidentifies mutated pathways in primary liver cancer.
Lowdon, Rebecca F;Wang, Ting
U24ES026699 PLoS One (2017) 28333948
2017
Epigenomic reprogramming in inorganicarsenic-mediated gene expression patterns duringcarcinogenesi ...
Eckstein, Meredith;Eleazer, Rebekah; Rea,Matthew;Fondufe-Mittendorf,Yvonne
R01ES024478 Rev Environ Health (2017Mar 01)
27701139
2017
ETV2/ER71 regulates hematopoietic regeneration bypromoting hematopoietic stem cell proliferation.
Xu, Can-Xin; Lee,Tae-Jin; Sakurai,Nagisa; Krchma, Karen;Liu, Fang; Li, Daofeng;Wang, Ting ...
U24ES026699 J Exp Med (2017 06 05) 28461595
2017
Expression quantitative trait loci (eQTLs) in humanplacentas suggest developmental origins of compl ...
Peng, Shouneng;Deyssenroth, Maya A;Di Narzo, Antonio F;Lambertini, Luca;Marsit, Carmen J; C ...
P30ES023515,R01ES025145,R01ES025145,R24ES028507
Hum Mol Genet (2017 0901)
28854703
2017
Fathers Matter: Why It's Time to Consider the Impactof Paternal Environmental Exposures on Children ...
Braun, Joseph M;Messerlian, Carmen;Hauser, Russ
P30ES000002,R01ES009718,R01ES009718,R01ES025214
Curr Epidemiol Rep (2017Mar)
28848695
2017
Forging Ahead through Darkness: PCNA, Still thePrincipal Conductor at the Replication Fork.
Choe, Katherine N;Moldovan,George-Lucian
R01ES026184 Mol Cell (2017 Feb 02) 28157503
2017
From the Cover: Manganese Stimulates MitochondrialH2O2 Production in SH-SY5Y Human NeuroblastomaCe ...
Fernandes, Jolyn; Hao,Li; Bijli, Kaiser M;Chandler, Joshua D;Orr, Michael; Hu, Xin;Jones, ...
P30ES019776,R01ES023485
Toxicol Sci (2017 01) 27701121
2017
Functional cis-regulatory modules encoded bymouse-specific endogenous retrovirus.
Sundaram, Vasavi;Choudhary, Mayank NK; Pehrsson, Erica;Xing, Xiaoyun; Fiore,Christopher; Pa ...
U24ES026699 Nat Commun (2017 03 28) 28348391
2017
Generational comparisons (F1 versus F3) ofvinclozolin induced epigenetic transgenerationalinherita ...
Beck, Daniel;Sadler-Riggleman,Ingrid; Skinner,Michael K
R01ES012974,R01ES012974
Environ Epigenet (2017Jul)
29147574
2017
Genome-wide DNA methylation reprogramming inresponse to inorganic arsenic links inhibition of CTCF...
Rea, Matthew; Eckstein,Meredith; Eleazer,Rebekah; Smith,Caroline;Fondufe-Mittendorf,Yvonne ...
R01ES024478 Sci Rep (2017 02 02) 28150704
2017
Genome-wide transcription-coupled repair inEscherichia coli is mediated by the Mfd translocase.
Adebali, Ogun; Chiou,Yi-Ying; Hu, Jinchuan;Sancar, Aziz; Selby,Christopher P
R01ES027255 Proc Natl Acad Sci U S A(2017 03 14)
28167766
2017
Gestational exposure to endocrine disruptingchemicals in relation to infant birth weight: a Bayesia...
Woods, Meghan M;Lanphear, Bruce P;Braun, Joseph M;McCandless, LawrenceC
R01ES025214 Environ Health (2017 1027)
29078782
2017
Human CRL4DDB2 ubiquitin ligase preferentiallyregulates post-repair chromatin restoration of H3K56A...
Zhu, Qianzheng; Wei,Shengcai; Sharma,Nidhi; Wani, Gulzar;He, Jinshan; Wani,Altaf A
R01ES012991 Oncotarget (2017 Nov 28) 29262658
2017
Human DNA polymerase η accommodates RNA forstrand extension.
Su, Yan; Egli, Martin;Guengerich, F Peter
R01ES010546,R01ES026955
J Biol Chem (2017 11 03) 28972162
2017
Human genome-wide repair map of DNA damagecaused by the cigarette smoke carcinogenbenzo[a]pyrene.
Li, Wentao; Hu,Jinchuan; Adebali,Ogun; Adar, Sheera;Yang, Yanyan; Chiou,Yi-Ying; Sancar, ...
P30ES010126,R01ES027255
Proc Natl Acad Sci U S A(2017 06 27)
28607059
2017
Human RAD52 interactions with replication protein Aand the RAD51 presynaptic complex.
Ma, Chu Jian; Kwon,Youngho; Sung,Patrick; Greene, Eric C
R01ES007061 J Biol Chem (2017 07 14) 28551686
2017
Identification of a unique gene expression signature inmercury and 2,3,7,8-tetrachlorodibenzo-p-dio ...
Jagannathan,Lakshmanan; Jose,Cynthia C; Tanwar,Vinay Singh;Bhattacharya, Sudin;Cuddapah, S ...
P30ES000260,R01ES024727
Toxicol Res (Camb) (2017May 01)
29057067
2017
Identification of critical base pairs required for CTCFbinding in motif M1 and M2.
Li, Wufeng; Shang,Liping; Huang,Kaimeng; Li, Jiao;Wang, Zhibin; Yao,Hongjie
R01ES025761,R01ES025761
Protein Cell (2017 07) 28315159
2017
Incorporation of Biological Knowledge Into the Studyof Gene-Environment Interactions.
Ritchie, Marylyn D;Davis, Joe R; Aschard,Hugues; Battle, Alexis;Conti, David; Du,Mengmeng; ...
P30ES007048,P30ES013508,R35ES028379
Am J Epidemiol (2017 Oct01)
28978191
2017
Interstrand cross-links arising from strand breaks attrue abasic sites in duplex DNA.
Yang, Zhiyu; Price,Nathan E; Johnson,Kevin M; Wang,Yinsheng; Gates, KentS
R01ES021007,T32ES018827
Nucleic Acids Res (2017Jun 20)
28531327
2017
Is it time to reassess current safety standards forglyphosate-based herbicides?
Vandenberg, Laura N;Blumberg, Bruce;Antoniou, Michael N;Benbrook, Charles M;Carroll, Lynn; ...
R01ES023316,R01ES023316
J Epidemiol CommunityHealth (2017 Jun)
28320775
2017
Lessons Learned From Past Gene-EnvironmentInteraction Successes.
Ritz, Beate R;Chatterjee, Nilanjan;Garcia-Closas,Montserrat; Gauderman,W James; Pierce, Bra ...
P30ES007048,R35ES028379
Am J Epidemiol (2017 Oct01)
28978190
2017
Linking Genes to Microbial Biogeochemical Cycling:Lessons from Arsenic.
Zhu, Yong-Guan; Xue,Xi-Mei; Kappler,Andreas; Rosen, BarryP; Meharg, Andrew A
R01ES023779 Environ Sci Technol (2017Jul 05)
28602082
2017
Liquid Chromatography-Tandem Mass Spectrometryfor the Quantification of Tobacco-Specific Nitrosamin...
Leng, Jiapeng; Wang,Yinsheng
R01ES025121 Anal Chem (2017 09 05) 28749651
2017
Machine learning for epigenetics and future medicalapplications.
Holder, Lawrence B;Haque, M Muksitul;Skinner, Michael K
R01ES012974,R01ES012974
Epigenetics (2017 07 03) 28524769
2017
Mass Spectrometry Based Proteomics Study ofCisplatin-Induced DNA-Protein Cross-Linking inHuman Fib ...
Ming, Xun; Groehler4th, Arnold;Michaelson-Richie,Erin D; Villalta, PeterW; Campbell, Colin; ...
R01ES023350 Chem Res Toxicol (201704 17)
28282121
2017
Mass Spectrometry-Based Tools to CharacterizeDNA-Protein Cross-Linking by Bis-Electrophiles.
Groehler 4th, Arnold;Degner, Amanda;Tretyakova, Natalia Y
R01ES023350 Basic Clin PharmacolToxicol (2017 Sep)
28032943
2017
Maternal serum PFOA concentration and DNAmethylation in cord blood: A pilot study.
Kingsley, Samantha L;Kelsey, Karl T; Butler,Rondi; Chen, Aimin;Eliot, Melissa N;Romano, Me ...
R01ES025214 Environ Res (2017 10) 28645023
2017
Mechanism of DNA alkylation-induced transcriptionalstalling, lesion bypass, and mutagenesis.
Xu, Liang; Wang, Wei;Wu, Jiabin; Shin, JiHyun; Wang,Pengcheng; Unarta,Ilona Christy; Chong ...
R01ES025121 Proc Natl Acad Sci U S A(2017 08 22)
28784758
2017
Mercury-induced epigenetic transgenerationalinheritance of abnormal neurobehavior is correlatedwit ...
Carvan 3rd, Michael J;Kalluvila, Thomas A;Klingler, Rebekah H;Larson, Jeremy K;Pickens, Mat ...
R01ES012974,R01ES012974
PLoS One (2017) 28464002
2017
Metabolism disrupting chemicals and metabolicdisorders.
Heindel, Jerrold J;Blumberg, Bruce; Cave,Mathew; Machtinger,Ronit; Mantovani,Alberto; Mende ...
R01ES023316,R01ES023316
Reprod Toxicol (2017 03) 27760374
2017
Methodology to Identify Poly-ADP-RibosePolymerase 1 (PARP1)-mRNA Targets by PAR-CLiP.
Melikishvili, Manana;Matveeva, Elena;Fondufe-Mittendorf,Yvonne
R01ES024478 Methods Mol Biol (2017) 28695513
2017
Mfd Protein and Transcription-Repair Coupling inEscherichia coli.
Selby, Christopher P R01ES027255 Photochem Photobiol(2017 01)
27864884
2017
Mfd translocase is necessary and sufficient fortranscription-coupled repair in Escherichia coli.
Adebali, Ogun; Sancar,Aziz; Selby,Christopher P
R01ES027255 J Biol Chem (2017 11 10) 28986449
2017
Microarray dataset of transient and permanent DNAmethylation changes in HeLa cells undergoing inorg ...
Eckstein, Meredith;Rea, Matthew;Fondufe-Mittendorf,Yvonne N
R01ES024478 Data Brief (2017 Aug) 28589171
2017
MicroRNAs Induce a Permissive ChromatinEnvironment that Enables Neuronal Subtype-SpecificReprogram ...
Abernathy, Daniel G;Kim, Woo Kyung;McCoy, Matthew J;Lake, Allison M;Ouwenga, Rebecca;Lee, ...
U24ES026699 Cell Stem Cell (2017 0907)
28886366
2017
miR-155 mediates arsenic trioxide resistance byactivating Nrf2 and suppressing apoptosis in lung ca ...
Gu, Shiyan; Lai,Yanhao; Chen, Hongyu;Liu, Yuan; Zhang,Zunzhen
R01ES023569 Sci Rep (2017 09 22) 28939896
2017
Modulation of trinucleotide repeat instability by DNApolymerase β polymorphic variant R137Q.
Ren, Yaou; Lai,Yanhao; Laverde,Eduardo E; Lei,Ruipeng; Rein, HayleyL; Liu, Yuan
R01ES023569 PLoS One (2017) 28475635
2017
Molecular mechanisms and genomic maps of DNAexcision repair in Escherichia coli and humans.
Hu, Jinchuan; Selby,Christopher P; Adar,Sheera; Adebali, Ogun;Sancar, Aziz
P30ES010126,R01ES027255
J Biol Chem (2017 09 22) 28798238
2017
Multivariate Bayesian variable selection exploitingdependence structure among outcomes: Application ...
Lee, Kyu Ha; Tadesse,Mahlet G; Baccarelli,Andrea A; Schwartz,Joel; Coull, Brent A
P30ES000002,P30ES009089,R01ES027747
Biometrics (2017 03) 27377873
2017
Mutagenicity of a Model DNA-Peptide Cross-Link inHuman Cells: Roles of Translesion Synthesis DNA Po...
Pande, Paritosh; Ji,Shaofei; Mukherjee,Shivam; Schärer,Orlando D; Tretyakova,Natalia Y; Bas ...
R01ES023350 Chem Res Toxicol (2017Feb 20)
27951635
2017
Nanoarmoring: strategies for preparation ofmulti-catalytic enzyme polymer conjugates andenhancemen ...
Zore, Omkar V; Pande,Paritosh; Okifo,Oghenenyerovwo;Basu, Ashis K; Kasi,Rajeswari M; Kumar, ...
R01ES023350 RSC Adv (2017) 29403641
2017
Nickel induces transcriptional down-regulation ofDNA repair pathways in tumorigenic and non-tumorig...
Scanlon, Susan E;Scanlon, Christine D;Hegan, Denise C;Sulkowski, Parker L;Glazer, Peter M
R01ES005775 Carcinogenesis (2017 0601)
28472268
2017
Nickel-induced HIF-1α promotes growth arrest andsenescence in normal human cells but lacks toxic ef ...
Luczak, Michal W;Zhitkovich, Anatoly
R01ES008786 Toxicol Appl Pharmacol(2017 09 15)
28552779
2017
Nonsynonymous Polymorphisms in the HumanAS3MT Arsenic Methylation Gene: Implications forArsenic To ...
Li, Jiaojiao;Packianathan, Charles;Rossman, Toby G;Rosen, Barry P
R01ES023779 Chem Res Toxicol (201707 17)
28537708
2017
Nrf2 regulates gene-environment interactions in ananimal model of intrauterine inflammation: Implic ...
Sussan, Thomas E;Sudini, Kuladeep;Talbot Jr, C Conover;Wang, Xiaobin;Wills-Karp, Marsha; Bu...
U01ES026721 Sci Rep (2017 01 10) 28071748
2017
Nucleosome Histone Tail Conformation andDynamics: Impacts of Lysine Acetylation and aNearby Minor ...
Fu, Iwen; Cai, Yuqin;Geacintov, Nicholas E;Zhang, Yingkai;Broyde, Suse
R01ES025987 Biochemistry (2017 04 11) 28304160
2017
Nucleosome-like, Single-stranded DNA(ssDNA)-Histone Octamer Complexes and theImplication for DNA D ...
Adkins, Nicholas L;Swygert, Sarah G; Kaur,Parminder; Niu,Hengyao; Grigoryev,Sergei A; Sung, ...
P30ES025128,R01ES007061
J Biol Chem (2017 Mar31)
28202543
2017
Nucleotide Excision Repair Lesion-RecognitionProtein Rad4 Captures a Pre-Flipped Partner Base in a...
Mu, Hong; Geacintov,Nicholas E; Min,Jung-Hyun; Zhang,Yingkai; Broyde, Suse
R01ES025987 Chem Res Toxicol (201706 19)
28460163
2017
Nucleotide Excision Repair: Finely Tuned MolecularOrchestra of Early Pre-incision Events.
Zhu, Qianzheng; Wani,Altaf A
R01ES012991 Photochem Photobiol(2017 01)
27696486
2017
Nucleotide selectivity defect and mutator phenotypeconferred by a colon cancer-associated DNA polym ...
Mertz, T M;Baranovskiy, A G;Wang, J; Tahirov, T H;Shcherbakova, P V
R01ES015869 Oncogene (2017 Aug) 28368425
2017
PARPi focus the spotlight on replication forkprotection in cancer.
Schlacher, Katharina R01ES029680 Nat Cell Biol (2017 Oct31)
29087384
2017
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nucleaseensemble in the processing of DNA-bound obstacles.
Wang, Weibin; Daley,James M; Kwon,Youngho; Krasner,Danielle S; Sung,Patrick
R01ES007061 Genes Dev (2017 12 01) 29321177
2017
PostExcision Events in Human Nucleotide ExcisionRepair.
Kemp, Michael G; Hu,Jinchuan
R01ES027255 Photochem Photobiol(2017 01)
27645806
2017
Prenatal arsenic exposure alters REST/NRSF andmicroRNA regulators of embryonic neural stem cellfat ...
Tyler, Christina R;Labrecque, Matthew T;Solomon, Elizabeth R;Guo, Xun; Allan,Andrea M
R01ES019583 Neurotoxicol Teratol (2017Jan - Feb)
27751817
2017
Protection of Nrf2 against arsenite-induced oxidativedamage is regulated by the cyclic guanosine mo ...
Chen, Chengzhi; Jiang,Xuejun; Gu, Shiyan;Lai, Yanhao; Liu, Yuan;Zhang, Zunzhen
R01ES023569 Environ Toxicol (2017Aug)
27774770
2017
Rapid Recall Ability of Memory T cells is Encoded intheir Epigenome.
Barski, Artem;Cuddapah, Suresh;Kartashov, Andrey V;Liu, Chong; Imamichi,Hiromi; Yang, Wenj ...
R01ES024727 Sci Rep (2017 01 05) 28054639
2017
Recurrent horizontal transfer of arsenitemethyltransferase genes facilitated adaptation of life to...
Chen, Song-Can; Sun,Guo-Xin; Rosen, BarryP; Zhang, Si-Yu; Deng,Ye; Zhu, Bo-Kai;Rensing, C ...
R01ES023779 Sci Rep (2017 08 10) 28798375
2017
Redox dynamics of manganese as a mitochondriallife-death switch.
Smith, Matthew Ryan;Fernandes, Jolyn; Go,Young-Mi; Jones, DeanP
R01ES023485 Biochem Biophys ResCommun (2017 01 15)
28212723
2017
Redox theory of aging: implications for health anddisease.
Go, Young-Mi; Jones,Dean P
P30ES019776,R01ES023485
Clin Sci (Lond) (2017 Jul15)
28667066
2017
Regulation of drug metabolism and toxicity bymultiple factors of genetics, epigenetics, lncRNAs, gu...
Yu, Ai-Ming;Ingelman-Sundberg,Magnus; Cherrington,Nathan J; Aleksunes,Lauren M; Zanger, Ulr...
P30ES005022,P30ES006694,P30ES010126,R01ES024421
Acta Pharm Sin B (201703)
28388695
2017
Relevance of iPSC-derived human PGC-like cells atthe surface of embryoid bodies to prechemotaxis mi ...
Mitsunaga, Shino;Odajima, Junko;Yawata, Shiomi;Shioda, Keiko; Owa,Chie; Isselbacher, Kurt...
R01ES023316,R01ES023316
Proc Natl Acad Sci U S A(2017 11 14)
29087313
2017
Removal of oxidatively generated DNA damage byoverlapping repair pathways.
Shafirovich, Vladimir;Geacintov, Nicholas E
R01ES027059 Free Radic Biol Med (201706)
27818219
2017
Repair-Resistant DNA Lesions. Geacintov, Nicholas E;Broyde, Suse
R01ES025987 Chem Res Toxicol (201708 21)
28750166
2017
Replication and repair of a reduced2΄-deoxyguanosine-abasic site interstrand cross-link inhuman ce ...
Price, Nathan E; Li, Lin;Gates, Kent S; Wang,Yinsheng
R01ES021007,T32ES018827
Nucleic Acids Res (2017Jun 20)
28431012
2017
Replicative DNA polymerase defects in humancancers: Consequences, mechanisms, and implicationsfor ...
Barbari, Stephanie R;Shcherbakova, Polina V
R01ES015869 DNA Repair (Amst) (201708)
28687338
2017
Reply to "Comment on 'On the Utility of ToxCast™and ToxPi as Methods for Identifying New Obesogens'...
Janesick, Amanda S;Dimastrogiovanni,Giorgio;Chamorro-Garcia,Raquel; Blumberg,Bruce
R01ES023316,R01ES023316
Environ Health Perspect(2017 01 01)
28055946
2017
Retinoid X Receptor Activation Alters the ChromatinLandscape To Commit Mesenchymal Stem Cells to th...
Shoucri, Bassem M;Martinez, Eric S;Abreo, Timothy J;Hung, Victor T;Moosova, Zdena;Shioda, ...
R01ES023316,R01ES023316
Endocrinology (2017 1001)
28977589
2017
Reversible DNA-Protein Cross-Linking at EpigeneticDNA Marks.
Ji, Shaofei; Shao,Hongzhao; Han,Qiyuan; Seiler,Christopher L;Tretyakova, Natalia Y
R01ES023350 Angew Chem Int Ed Engl(2017 11 06)
28898504
2017
Role of DNA polymerase β oxidized nucleotideinsertion in DNA ligation failure.
Çaglayan, Melike;Wilson, Samuel H
R00ES026191 J Radiat Res (2017 Sep 01) 28992331
2017
Role of the Pif1-PCNA Complex in Pol δ-DependentStrand Displacement DNA Synthesis andBreak-Induced ...
Buzovetsky, Olga;Kwon, Youngho; Pham,Nhung Tuyet; Kim,Claire; Ira, Grzegorz;Sung, Patrick; ...
R01ES007061 Cell Rep (2017 Nov 14) 29141206
2017
Selective Nrf2 Gene Deletion in the RostralVentrolateral Medulla Evokes Hypertension andSympathoex ...
Gao, Lie; Zimmerman,Matthew C; Biswal,Shyam; Zucker, IrvingH
U01ES026721 Hypertension (2017 06) 28461605
2017
SENP8 limits aberrant neddylation of NEDD8pathway components to promote cullin-RINGubiquitin ligas ...
Coleman, Kate E;Békés, Miklós;Chapman, Jessica R;Crist, Sarah B; Jones,Mathew Jk; Ueberheid...
R01ES025166 Elife (2017 05 05) 28475037
2017
Sequence imperfections and base triplet recognition bythe Rad51/RecA family of recombinases.
Lee, Ja Yil; Steinfeld,Justin B; Qi, Zhi;Kwon, YoungHo; Sung,Patrick; Greene, Eric C
R01ES007061 J Biol Chem (2017 06 30) 28476890
2017
Sequence-Specific Covalent Capture Coupled withHigh-Contrast Nanopore Detection of aDisease-Derive ...
Nejad, Maryam Imani;Shi, Ruicheng; Zhang,Xinyue; Gu, Li-Qun;Gates, Kent S
R01ES021007 Chembiochem (2017 0718)
28422400
2017
Sex-Differential Responses of TumorPromotion-Associated Genes and Dysregulation ofNovel Long Nonco ...
Lodato, Nicholas J;Melia, Tisha;Rampersaud, Andy;Waxman, David J
R01ES024421 Toxicol Sci (2017 09 01) 28903501
2017
Sexually Dimorphic Effects of Early-Life Exposuresto Endocrine Disruptors: Sex-Specific Epigenetic ...
McCabe, Carolyn;Anderson, Olivia S;Montrose, Luke; Neier,Kari; Dolinoy, Dana C
P30ES017885,T32ES007062,U01ES026697
Curr Environ Health Rep(2017 12)
28980159
2017
Structure-activity relationships among DNA ligaseinhibitors: Characterization of a selective uncomp ...
Howes, Timothy R L;Sallmyr, Annahita;Brooks, Rhys; Greco,George E; Jones, DarinE; Matsumoto ...
R01ES012512 DNA Repair (Amst) (201712)
29078112
2017
TALEN-Mediated FLAG-Tagging of EndogenousHistone Methyltransferase DOT1L.
An, Cheng; Zhu,Guangjing; Martos,Suzanne N; Feng, Xue;Zhang, Haimou; Jia,Yankai; Wang, Zh ...
R01ES025761,R01ES025761
Adv Biosci Biotechnol(2017 Sep)
29796335
2017
The association between telomere length and mortalityin Bangladesh.
Dean, Samantha G;Zhang, Chenan; Gao,Jianjun; Roy, Shantanu;Shinkle, Justin;Sabarinathan, M ...
P42ES010349,R35ES028379
Aging (Albany NY) (2017Jun 15)
28630379
2017
The Cartography of UV-induced DNA DamageFormation and DNA Repair.
Hu, Jinchuan; Adar,Sheera
R01ES027255 Photochem Photobiol(2017 01)
27861959
2017
The essential kinase ATR: ensuring faithfulduplication of a challenging genome.
Saldivar, Joshua C;Cortez, David;Cimprich, Karlene A
R01ES016486 Nat Rev Mol Cell Biol(2017 10)
28811666
2017
The Human Ligase IIIα-XRCC1 Protein ComplexPerforms DNA Nick Repair after TransientUnwrapping of N ...
Cannan, Wendy J;Rashid, Ishtiaque;Tomkinson, Alan E;Wallace, Susan S;Pederson, David S
R01ES012512 J Biol Chem (2017 Mar31)
28184006
2017
The Nonbulky DNA Lesions Spiroiminodihydantoinand 5-Guanidinohydantoin Significantly Block HumanRN ...
Kolbanovskiy, Marina;Chowdhury, MoinuddinA; Nadkarni, Aditi;Broyde, Suse;Geacintov, Nichola ...
R01ES025987,R01ES027059
Biochemistry (2017 06 20) 28514164
2017
The unexpected teratogenicity of RXR antagonistUVI3003 via activation of PPARγ in Xenopus tropicali...
Zhu, Jingmin; Janesick,Amanda; Wu, Lijiao;Hu, Lingling; Tang,Weiyi; Blumberg,Bruce; Shi, ...
R01ES023316,R01ES023316
Toxicol Appl Pharmacol(2017 Jan 01)
27894914
2017
Tissue-specific DNA methylation is conserved acrosshuman, mouse, and rat, and driven by primary seq ...
Zhou, Jia; Sears, ReneeL; Xing, Xiaoyun;Zhang, Bo; Li, Daofeng;Rockweiler, Nicole B;Jang, ...
U24ES026699 BMC Genomics (2017 Sep12)
28899353
2017
Transient and permanent changes in DNA methylationpatterns in inorganic arsenic-mediated epithelial ...
Eckstein, Meredith;Rea, Matthew;Fondufe-Mittendorf,Yvonne N
R01ES024478 Toxicol Appl Pharmacol(2017 09 15)
28336213
2017
Translesion synthesis DNA polymerases promoteerror-free replication through the minor-groove DNAad ...
Yoon, Jung-Hoon; RoyChoudhury, Jayati;Park, Jeseong; Prakash,Satya; Prakash, Louise
R01ES022948 J Biol Chem (2017 11 10) 28939775
2017
Translesion Synthesis of 2'-Deoxyguanosine Lesionsby Eukaryotic DNA Polymerases.
Basu, Ashis K; Pande,Paritosh; Bose,Arindam
R01ES021762,R01ES023350
Chem Res Toxicol (201701 17)
27760288
2017
Two approaches reveal a new paradigm of 'switchableor genetics-influenced allele-specific DNA methy ...
Martos, Suzanne N; Li,Teng; Ramos, RamonBossardi; Lou, Dan;Dai, Hongzheng; Xu,Jin-Chong; G ...
R01ES025761,R01ES025761,T32ES007141
Cell Discov (2017) 29387450
2017
Ultrathin Graphene-Protein Supercapacitors forMiniaturized Bioelectronics.
Mosa, Islam M;Pattammattel, Ajith;Kadimisetty, Karteek;Pande, Paritosh;El-Kady, Maher F; Bi...
R01ES023350 Adv Energy Mater (2017Sep 06)
29104523
2017
Uncovering the transcriptomic and epigenomiclandscape of nicotinic receptor genes in non-neuronal t...
Zhang, Bo; Madden,Pamela; Gu, Junchen;Xing, Xiaoyun; Sankar,Savita; Flynn, Jennifer;Kroll, ...
U24ES026699 BMC Genomics (2017 0605)
28583088
2017
UV radiation-induced SUMOylation of DDB2regulates nucleotide excision repair.
Han, Chunhua; Zhao,Ran; Kroger, John; He,Jinshan; Wani, Gulzar;Wang, Qi-En; Wani,Altaf A
R01ES012991 Carcinogenesis (2017 1001)
28981631
2017
UV-induced proteolysis of RNA polymerase II ismediated by VCP/p97 segregase and timelyorchestratio ...
He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Wani, Altaf A
R01ES012991 Oncotarget (2017 Feb 14) 28036256
2017
Variation in Extracellular Detoxification Is a Link toDifferent Carcinogenicity among Chromates in ...
Krawic, Casey; Luczak,Michal W; Zhitkovich,Anatoly
R01ES008786 Chem Res Toxicol (201709 18)
28759204
2017
Whole-Genome DNA Methylation Profiling IdentifiesEpigenetic Signatures of Uterine Carcinosarcoma.
Li, Jing; Xing,Xiaoyun; Li, Daofeng;Zhang, Bo; Mutch,David G; Hagemann,Ian S; Wang, Ting
U24ES026699 Neoplasia (2017 02) 28088687
2017
Whole-transcriptome analysis delineates the humanplacenta gene network and its associations with fe ...
Deyssenroth, Maya A;Peng, Shouneng; Hao,Ke; Lambertini, Luca;Marsit, Carmen J; Chen,Jia
P30ES023515,R01ES025145,R01ES025145,R24ES028507
BMC Genomics (2017 0710)
28693416
2017
xMSannotator: An R Package for Network-BasedAnnotation of High-Resolution Metabolomics Data.
Uppal, Karan; Walker,Douglas I; Jones, DeanP
P30ES019776,R01ES023485
Anal Chem (2017 01 17) 27977166
2017
Yale school of public health symposium on lifetimeexposures and human health: the exposome; summary...
Johnson, Caroline H;Athersuch, Toby J;Collman, Gwen W;Dhungana, Suraj; Grant,David F; Jones ...
P30ES019776,R01ES023485,U2CES026560
Hum Genomics (2017 Dec08)
29221465
2017
Yeast DNA polymerase ζ maintains consistent activityand mutagenicity across a wide range of physiol ...
Kochenova, Olga V;Bezalel-Buch, Rachel;Tran, Phong; Makarova,Alena V; Chabes,Andrei; Burger ...
R01ES015869 Nucleic Acids Res (201702 17)
28180291
2017
Yeast Srs2 Helicase Promotes Redistribution ofSingle-Stranded DNA-Bound RPA and Rad52 inHomologous ...
De Tullio, Luisina;Kaniecki, Kyle; Kwon,Youngho; Crickard, JBrooks; Sung, Patrick;Greene, ...
R01ES007061 Cell Rep (2017 Oct 17) 29045827
2017
Aberrant DNA Methylation of Phosphodiesterase[corrected] 4D Alters Airway Smooth Muscle CellPhenot ...
Lin, Amanda H Y;Shang, Yan; Mitzner,Wayne; Sham, James SK; Tang, Wan-yee
R01ES024784 Am J Respir Cell Mol Biol(2016 Feb)
26181301
2016
An essential role for UTX in resolution and activationof bivalent promoters.
Dhar, Shilpa S; Lee,Sung-Hun; Chen, Kaifu;Zhu, Guangjing; Oh,WonKyung; Allton,Kendra; Gafn ...
R01ES025761,R01ES025761
Nucleic Acids Res (201605 05)
26762983
2016
Ancestral vinclozolin exposure alters the epigenetictransgenerational inheritance of sperm small no ...
Schuster, Andrew;Skinner, Michael K;Yan, Wei
R01ES012974,R01ES012974
Environ Epigenet (2016) 27390623
2016
AP endonuclease 1 prevents the extension of a T/Gmismatch by DNA polymerase β to prevent mutations...
Lai, Yanhao; Jiang,Zhongliang; Zhou, Jing;Osemota, Emmanuel;Liu, Yuan
R01ES023569 DNA Repair (Amst) (201607)
27183823
2016
Arsenic Directly Binds to and Activates the YeastAP-1-Like Transcription Factor Yap8.
Kumar, Nallani Vijay;Yang, Jianbo; Pillai,Jitesh K; Rawat, Swati;Solano, Carlos; Kumar,Abh ...
R01ES023779 Mol Cell Biol (2016 Mar) 26711267
2016
ATR- and ATM-Mediated DNA Damage Response IsDependent on Excision Repair Assembly during G1but Not ...
Ray, Alo; Blevins,Chessica; Wani, Gulzar;Wani, Altaf A
R01ES012991 PLoS One (2016) 27442013
2016
Bypass of DNA-Protein Cross-links Conjugated to the7-Deazaguanine Position of DNA by Translesion Sy ...
Wickramaratne, Susith;Ji, Shaofei; Mukherjee,Shivam; Su, Yan;Pence, Matthew G;Lior-Hoffmann ...
R01ES010546,R01ES023350,R01ES025987
J Biol Chem (2016 Nov04)
27621316
2016
Chemical and Hormonal Effects onSTAT5b-Dependent Sexual Dimorphism of the LiverTranscriptome.
Oshida, Keiyu;Waxman, David J;Corton, J Christopher
R01ES024421 PLoS One (2016) 26959237
2016
Cisplatin DNA damage and repair maps of the humangenome at single-nucleotide resolution.
Hu, Jinchuan; Lieb,Jason D; Sancar, Aziz;Adar, Sheera
P30ES010126,R01ES027255
Proc Natl Acad Sci U S A(2016 10 11)
27688757
2016
Comparative analysis of linker histone H1, MeCP2,and HMGD1 on nucleosome stability and target site ...
Riedmann, Caitlyn;Fondufe-Mittendorf,Yvonne N
R01ES024478 Sci Rep (2016 09 14) 27624769
2016
Comparative Error-Free and Error-Prone TranslesionSynthesis of N(2)-2'-Deoxyguanosine Adducts Forme...
Bose, Arindam;Surugihalli, Chaitra;Pande, Paritosh;Champeil, Elise; Basu,Ashis K
R01ES023350 Chem Res Toxicol (201605 16)
27082015
2016
Computational Metabolomics: A Framework for theMillion Metabolome.
Uppal, Karan; Walker,Douglas I; Liu, Ken; Li,Shuzhao; Go,Young-Mi; Jones, DeanP
P30ES019776,R01ES023485,T32ES012870,U2CES026560
Chem Res Toxicol (201612 19)
27629808
2016
Concerns over use of glyphosate-based herbicides andrisks associated with exposures: a consensus st ...
Myers, John Peterson;Antoniou, Michael N;Blumberg, Bruce;Carroll, Lynn; Colborn,Theo; Evere ...
R01ES023316,R01ES023316
Environ Health (2016 Feb17)
26883814
2016
Covalent DNA-Protein Cross-Linking byPhosphoramide Mustard and Nornitrogen Mustard inHuman Cells.
Groehler 4th, Arnold;Villalta, Peter W;Campbell, Colin;Tretyakova, Natalia
R01ES023350 Chem Res Toxicol (2016Feb 15)
26692166
2016
Crosstalk between MSH2-MSH3 and polβ promotestrinucleotide repeat expansion during base excision re...
Lai, Yanhao; Budworth,Helen; Beaver, Jill M;Chan, Nelson L S;Zhang, Zunzhen;McMurray, Cynt ...
R01ES023569 Nat Commun (2016 08 22) 27546332
2016
Deployment-Associated Exposure Surveillance WithHigh-Resolution Metabolomics.
Walker, Douglas I;Mallon, Col TimothyM; Hopke, Philip K;Uppal, Karan; Go,Young-Mi; Rohrbeck ...
P30ES019776,R01ES023485,T32ES012870
J Occup Environ Med(2016 08)
27501099
2016
Developmental origins of epigenetic transgenerationalinheritance.
Hanson, Mark A;Skinner, Michael K
R01ES012974,R01ES012974
Environ Epigenet (2016) 27390622
2016
Different ATM Signaling in Response toChromium(VI) Metabolism via Ascorbate andNonascorbate Reduct ...
Luczak, Michal W;Green, Samantha E;Zhitkovich, Anatoly
R01ES008786 Environ Health Perspect(2016 Jan)
25977998
2016
Differential DNA lesion formation and repair inheterochromatin and euchromatin.
Han, Chunhua;Srivastava, AmitKumar; Cui, Tiantian;Wang, Qi-En; Wani,Altaf A
R01ES012991 Carcinogenesis (2016 Feb) 26717995
2016
Differential DNA methylation analysis optimallyrequires purified cell populations.
Skinner, Michael K R01ES012974,R01ES012974
Fertil Steril (2016 09 01) 27349925
2016
Directed evolution using dCas9-targeted somatichypermutation in mammalian cells.
Hess, Gaelen T;Frésard, Laure; Han,Kyuho; Lee, CameronH; Li, Amy; Cimprich,Karlene A; Mont ...
R01ES016486 Nat Methods (2016 Dec) 27798611
2016
Effective molarity in a nucleic acid-controlled reaction.
Catalano, Michael J;Price, Nathan E; Gates,Kent S
R01ES021007 Bioorg Med Chem Lett(2016 06 01)
27117430
2016
Endocrine disruptors in 2015: Epigenetictransgenerational inheritance.
Skinner, Michael K R01ES012974,R01ES012974
Nat Rev Endocrinol (2016Feb)
26585656
2016
Enrichment of Cdk1-cyclins at DNA double-strandbreaks stimulates Fun30 phosphorylation and DNAend ...
Chen, Xuefeng; Niu,Hengyao; Yu, Yang;Wang, Jingjing; Zhu,Shuangyi; Zhou, Jianjie;Papusha, ...
R01ES007061 Nucleic Acids Res (2016Apr 07)
26801641
2016
Epigenetic programming alterations in alligators fromenvironmentally contaminated lakes.
Guillette Jr, Louis J;Parrott, Benjamin B;Nilsson, Eric; Haque, MM; Skinner, Michael K
R01ES012974,R01ES012974
Gen Comp Endocrinol(2016 11 01)
27080547
2016
Epigenetic Therapeutics: A New Weapon in the WarAgainst Cancer.
Ahuja, Nita; Sharma,Anup R; Baylin,Stephen B
R01ES011858 Annu Rev Med (2016) 26768237
2016
Erasure of DNA methylation, genomic imprints, andepimutations in a primordial germ-cell model deriv ...
Miyoshi, Norikatsu;Stel, Jente M; Shioda,Keiko; Qu, Na;Odajima, Junko;Mitsunaga, Shino; Zh ...
R01ES023316,R01ES023316
Proc Natl Acad Sci U S A(2016 08 23)
27486249
2016
Estrogen Drives Cellular Transformation andMutagenesis in Cells Expressing the BreastCancer-Associ ...
Nemec, Antonia A;Bush, Korie B;Towle-Weicksel, JamieB; Taylor, B Frazier;Schulz, Vincent; W ...
R01ES019179 Mol Cancer Res (2016 11) 27621267
2016
Evolution of Telomeres in Schizosaccharomycespombe and Its Possible Relationship to the Diversifica...
Sepsiova, Regina;Necasova, Ivona;Willcox, Smaranda;Prochazkova, Katarina;Gorilak, Peter; No ...
R56ES013773 PLoS One (2016) 27101289
2016
Exposure Memory and Lung Regeneration. Go, Young-Mi; Jones,Dean P
R01ES023485 Ann Am Thorac Soc (201612)
28005420
2016
Expression of arsenic resistance genes in the obligateanaerobe Bacteroides vulgatus ATCC 8482, a gu ...
Li, Jiaojiao; Mandal,Goutam; Rosen, BarryP
R01ES023779 Anaerobe (2016 Jun) 27040269
2016
Genomic Clustering of differential DNA methylatedregions (epimutations) associated with the epigene ...
Haque, M Muksitul;Nilsson, Eric E; Holder,Lawrence B; Skinner,Michael K
R01ES012974,R01ES012974
BMC Genomics (2016 0601)
27245821
2016
How SUMOylation Fine-Tunes the Fanconi AnemiaDNA Repair Pathway.
Coleman, Kate E;Huang, Tony T
R01ES025166 Front Genet (2016) 27148358
2016
HUWE1 comes to the rescue at stalled replicationforks.
Coleman, Kate E;Huang, Tony T
R01ES025166 EMBO Rep (2016 06) 27146074
2016
HUWE1 interacts with PCNA to alleviate replicationstress.
Choe, Katherine N;Nicolae, Claudia M;Constantin, Daniel;Imamura Kawasawa,Yuka; Delgado-Diaz, ...
R01ES026184 EMBO Rep (2016 06) 27146073
2016
Hydrogen peroxide and central redox theory foraerobic life: A tribute to Helmut Sies: Scout, trailb ...
Jones, Dean P P30ES019776,R01ES023485,U2CES026560
Arch Biochem Biophys(2016 Apr 01)
27095208
2016
In Vitro Lesion Bypass Studies ofO(4)-Alkylthymidines with Human DNA Polymeraseη.
Williams, Nicole L;Wang, Pengcheng; Wu,Jiabin; Wang, Yinsheng
R01ES025121 Chem Res Toxicol (2016Apr 18)
27002924
2016
Inhibiting Mitochondrial DNA Ligase IIIα ActivatesCaspase 1-Dependent Apoptosis in Cancer Cells.
Sallmyr, Annahita;Matsumoto, Yoshihiro;Roginskaya, Vera; VanHouten, Bennett;Tomkinson, Alan ...
R01ES012512 Cancer Res (2016 09 15) 27503931
2016
Inhibition of DNA Methyltransferases Blocks MutantHuntingtin-Induced Neurotoxicity.
Pan, Yanchun; Daito,Takuji; Sasaki, Yo;Chung, Yong Hee;Xing, Xiaoyun;Pondugula, Santhi; Sw...
U24ES026699 Sci Rep (2016 08 12) 27516062
2016
Inhibition of ileal bile acid uptake protects againstnonalcoholic fatty liver disease in high-fat d ...
Rao, Anuradha;Kosters, Astrid; Mells,Jamie E; Zhang,Wujuan; Setchell,Kenneth D R; Amanso,...
P30ES019776,R01ES023485
Sci Transl Med (2016 0921)
27655848
2016
Involvement of PARP1 in the regulation of alternativesplicing.
Matveeva, Elena;Maiorano, John; Zhang,Qingyang; Eteleeb,Abdallah M;Convertini, Paolo;Chen, ...
R01ES024478 Cell Discov (2016) 27462443
2016
Low-dose oral cadmium increases airway reactivityand lung neuronal gene expression in mice.
Chandler, Joshua D;Wongtrakool, Cherry;Banton, Sophia A; Li,Shuzhao; Orr, MichaelL; Barr, ...
R01ES023485,T32ES012870
Physiol Rep (2016 Jul) 27401458
2016
Mass Spectrometry-Based Quantitative Strategies forAssessing the Biological Consequences and Repair ...
You, Changjun; Wang,Yinsheng
R01ES025121 Acc Chem Res (2016 Feb16)
26758048
2016
Maternal serum perfluoroalkyl substances duringpregnancy and duration of breastfeeding.
Romano, Megan E; Xu,Yingying; Calafat,Antonia M; Yolton,Kimberly; Chen, Aimin;Webster, Gle ...
P30ES006096,R01ES025214
Environ Res (2016 08) 27179585
2016
Mek1 Down Regulates Rad51 Activity during YeastMeiosis by Phosphorylation of Hed1.
Callender, Tracy L;Laureau, Raphaelle;Wan, Lihong; Chen,Xiangyu; Sandhu,Rima; Laljee, Saif ...
R01ES007061 PLoS Genet (2016 Aug) 27483004
2016
Metabolic Pathways and Networks Associated WithTobacco Use in Military Personnel.
Jones, Dean P; Walker,Douglas I; Uppal,Karan; Rohrbeck,Patricia; Mallon, ColTimothy M; Go, ...
P30ES019776,R01ES023485,T32ES012870
J Occup Environ Med(2016 08)
27501098
2016
Metabolic pathways of lung inflammation revealed byhigh-resolution metabolomics (HRM) of H1N1 influ ...
Chandler, Joshua D; Hu,Xin; Ko, Eun-Ju; Park,Soojin; Lee,Young-Tae; Orr,Michael; Fernandes ...
R01ES023485 Am J Physiol Regul IntegrComp Physiol (2016 11 01)
27558316
2016
Metabolomics and Mycobacterial Disease: Don'tForget the Bioinformatics.
Collins, Jeffrey M;Kempker, Russell R;Ziegler, Thomas R;Blumberg, Henry M;Jones, Dean P
P30ES019776,R01ES023485,T32ES012870
Ann Am Thorac Soc (2016Jan)
26730872
2016
miR-155 Overexpression Promotes GenomicInstability by Reducing High-fidelity PolymeraseDelta Expre ...
Czochor, Jennifer R;Sulkowski, Parker;Glazer, Peter M
R01ES005775 Mol Cancer Res (2016Apr)
26850462
2016
Mismatch repair proteins recruit DNAmethyltransferase 1 to sites of oxidative DNA damage.
Ding, Ning; Bonham,Emily M; Hannon,Brooke E; Amick,Thomas R; Baylin,Stephen B; O'Hagan,He ...
R01ES011858 J Mol Cell Biol (2016 06) 26186941
2016
New mechanisms of bacterial arsenic resistance. Yang, Hung-Chi;Rosen, Barry P
R01ES023779 Biomed J (2016 Feb) 27105594
2016
Nuclear Factor κB1/RelA Mediates Inflammation inHuman Lung Epithelial Cells at Atmospheric OxygenL ...
Jagannathan,Lakshmanan; Jose,Cynthia C; Arita,Adriana; Kluz, Thomas;Sun, Hong; Zhang,Xiao ...
P30ES000260,R01ES024727
J Cell Physiol (2016 Jul) 26588041
2016
Nuclear Thioredoxin-1 Overexpression AttenuatesAlcohol-Mediated Nrf2 Signaling and Lung Fibrosis.
Sueblinvong, Viranuj;Mills, Stephen T;Neujahr, David C; Go,Young-Mi; Jones, DeanP; Guidot, ...
R01ES023485 Alcohol Clin Exp Res(2016 09)
27436123
2016
Obesogens: an emerging threat to public health. Janesick, Amanda S;Blumberg, Bruce
R01ES023316,R01ES023316
Am J Obstet Gynecol(2016 05)
26829510
2016
On the Utility of ToxCast™ and ToxPi as Methods forIdentifying New Obesogens.
Janesick, AmandaShaine;Dimastrogiovanni,Giorgio; Vanek, Lenka;Boulos, Christy;Chamorro-Garc ...
R01ES023316,R01ES023316
Environ Health Perspect(2016 08)
26757984
2016
Oxidative stress under ambient and physiologicaloxygen tension in tissue culture.
Jagannathan,Lakshmanan;Cuddapah, Suresh;Costa, Max
P30ES000260,R01ES024727
Curr Pharmacol Rep (2016Apr)
27034917
2016
PARP10 deficiency manifests by severedevelopmental delay and DNA repair defect.
Shahrour, Maher Awni;Nicolae, Claudia M;Edvardson, Simon;Ashhab, Motee; Galvan,Adri M; Cons ...
R01ES026184 Neurogenetics (2016 10) 27624574
2016
Patterns of growth and tract formation during the earlydevelopment of secondary lineages in the Dro ...
Lovick, Jennifer K;Kong, Angel; Omoto,Jaison J; Ngo, Kathy T;Younossi-Hartenstein,Amelia; H ...
R01ES029357 Dev Neurobiol (2016 Apr) 26178322
2016
Placental Epigenetics in Children's EnvironmentalHealth.
Marsit, Carmen J P01ES022832,R01ES025145,R01ES025145
Semin Reprod Med (2016Jan)
26696277
2016
Proliferating cell nuclear antigen preventstrinucleotide repeat expansions by promoting repeatdele ...
Beaver, Jill M; Lai,Yanhao; Rolle, ShantellJ; Liu, Yuan
R01ES023569 DNA Repair (Amst) (201612)
27793507
2016
Promotion of RAD51-Mediated Homologous DNAPairing by the RAD51AP1-UAF1 Complex.
Liang, Fengshan;Longerich, Simonne;Miller, Adam S; Tang,Caroline; Buzovetsky,Olga; Xiong, ...
R01ES007061 Cell Rep (2016 06 07) 27239033
2016
Quantitative Mass Spectrometry Reveals Changes inHistone H2B Variants as Cells Undergo Inorganic Ar...
Rea, Matthew; Jiang,Tingting; Eleazer,Rebekah; Eckstein,Meredith; Marshall,Alan G; Fondufe- ...
R01ES024478 Mol Cell Proteomics (201607)
27169413
2016
Recognition of Lys48-Linked Di-ubiquitin andDeubiquitinating Activities of the SARS CoronavirusPap ...
Békés, Miklós; van derHeden van Noort,Gerbrand J; Ekkebus,Reggy; Ovaa, Huib;Huang, Tony T; ...
R01ES025166 Mol Cell (2016 05 19) 27203180
2016
Replicative Bypass of O2-Alkylthymidine Lesions inVitro.
Williams, Nicole L;Wang, Pengcheng;Wang, Yinsheng
R01ES025121 Chem Res Toxicol (201610 17)
27611246
2016
Reply. Janesick, Amanda S;Blumberg, Bruce
R01ES023316,R01ES023316
Am J Obstet Gynecol(2016 10)
27242202
2016
Reprogramming of the Epigenome by MLL1 LinksEarly-Life Environmental Exposures to ProstateCancer R ...
Wang, Quan; Trevino,Lindsey S; Wong,Rebecca Lee Yean;Medvedovic, Mario;Chen, Jing; Ho, Shu ...
P30ES006096,U01ES026719
Mol Endocrinol (2016Aug)
27219490
2016
Roles of Aag, Alkbh2, and Alkbh3 in the Repair ofCarboxymethylated and Ethylated Thymidine Lesions.
You, Changjun; Wang,Pengcheng; Nay,Stephanie L; Wang,Jianshuang; Dai,Xiaoxia; O'Connor, Ti...
R01ES025121,T32ES018827
ACS Chem Biol (2016 0520)
26930515
2016
SCR7 is neither a selective nor a potent inhibitor ofhuman DNA ligase IV.
Greco, George E;Matsumoto, Yoshihiro;Brooks, Rhys C; Lu,Zhengfei; Lieber,Michael R; Tomkins ...
R01ES012512 DNA Repair (Amst) (201607)
27235626
2016
Sequencing the exposome: A call to action. Jones, Dean P P30ES019776,R01ES023485,T32ES012870
Toxicol Rep (2016) 26722641
2016
Simple, High-Yield Syntheses of DNA DuplexesContaining Interstrand DNA-DNA Cross-LinksBetween an N ...
Gamboa Varela,Jacqueline; Gates, KentS
R01ES021007 Curr Protoc Nucleic AcidChem (2016 06 01)
27248783
2016
Small Molecule Inhibitor of NRF2 SelectivelyIntervenes Therapeutic Resistance inKEAP1-Deficient NS ...
Singh, Anju;Venkannagari,Sreedhar; Oh, Kyu H;Zhang, Ya-Qin; Rohde,Jason M; Liu, Li;Nimmag ...
R01ES025761,R01ES025761
ACS Chem Biol (2016 1118)
27552339
2016
Statistical Approaches for Assessing Health Effects ofEnvironmental Chemical Mixtures in Epidemiolo ...
Taylor, Kyla W;Joubert, Bonnie R;Braun, Joe M; Dilworth,Caroline; Gennings,Chris; Hauser, ...
P30ES023515,R01ES025214
Environ Health Perspect(2016 12 01)
27905274
2016
Tel1 and Rif2 Regulate MRX Functions inEnd-Tethering and Repair of DNA Double-StrandBreaks.
Cassani, Corinne;Gobbini, Elisa; Wang,Weibin; Niu, Hengyao;Clerici, Michela; Sung,Patrick; ...
R01ES007061 PLoS Biol (2016 Feb) 26901759
2016
Tertiary Epimutations - A Novel Aspect of EpigeneticTransgenerational Inheritance Promoting Genome ...
McCarrey, John R;Lehle, Jake D; Raju,Seetha S; Wang,Yufeng; Nilsson, EricE; Skinner, Micha ...
R01ES012974,R01ES012974
PLoS One (2016) 27992467
2016
The Metacaspase (Mca1p) Restricts O-glycosylationDuring Farnesol-induced Apoptosis in Candida albic...
Léger, Thibaut; Garcia,Camille; Camadro,Jean-Michel
R01ES024478 Mol Cell Proteomics (201607)
27125826
2016
The organoarsenical biocycle and the primordialantibiotic methylarsenite.
Li, Jiaojiao; Pawitwar,Shashank S; Rosen,Barry P
R01ES023779 Metallomics (2016 10 01) 27730229
2016
Translesion synthesis of O4-alkylthymidine lesions inhuman cells.
Wu, Jun; Li, Lin; Wang,Pengcheng; You,Changjun; Williams,Nicole L; Wang,Yinsheng
R01ES025121 Nucleic Acids Res (2016Nov 02)
27466394
2016
Uppsala Consensus Statement on EnvironmentalContaminants and the Global Obesity Epidemic.
Lind, Lars; Lind, PMonica; Lejonklou,Margareta H; Dunder,Linda; Bergman, Åke;Guerrero-Bosag ...
R01ES023316,R01ES023316
Environ Health Perspect(2016 05 01)
27135406
2016
Valosin-containing Protein (VCP)/p97 SegregaseMediates Proteolytic Processing of CockayneSyndrome ...
He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Sharma, Nidhi;Wani, Altaf A
R01ES012991 J Biol Chem (2016 Apr 01) 26826127
2016
Yeast DNA polymerase ζ maintains consistent activityand mutagenicity across a wide range of physiol ...
Kochenova, Olga V;Bezalel-Buch, Rachel;Tran, Phong; Makarova,Alena V; Chabes,Andrei; Burger ...
R01ES015869 Nucleic Acids Res (2016Nov 29)
27903904
2016
ZMYND8 Reads the Dual Histone MarkH3K4me1-H3K14ac to Antagonize the Expression ofMetastasis-Linked ...
Li, Na; Li, Yuanyuan;Lv, Jie; Zheng,Xiangdong; Wen,Hong; Shen, Hongjie;Zhu, Guangjing; Ch ...
R01ES025761,R01ES025761
Mol Cell (2016 08 04) 27477906
2016
A rolling circle replication mechanism producesmultimeric lariats of mitochondrial DNA in Caenorhab...
Lewis, Samantha C;Joers, Priit; Willcox,Smaranda; Griffith,Jack D; Jacobs, HowardT; Hyman, ...
R56ES013773 PLoS Genet (2015 Feb) 25693201
2015
A simple, high-yield synthesis of DNA duplexescontaining a covalent, thermally cleavable interstran ...
Gamboa Varela,Jacqueline; Gates, KentS
R01ES021007 Angew Chem Int Ed Engl(2015 Jun 22)
25967397
2015
Anticancer therapeutic potential of Mnporphyrin/ascorbate system.
Tovmasyan, Artak;Sampaio, Romulo S;Boss, Mary-Keara;Bueno-Janice,Jacqueline C; Bader,Bader ...
R01ES023485 Free Radic Biol Med (2015Dec)
26496207
2015
AP endonuclease 1 prevents trinucleotide repeatexpansion via a novel mechanism during base excision...
Beaver, Jill M; Lai,Yanhao; Xu, Meng;Casin, Astrid H;Laverde, Eduardo E;Liu, Yuan
R01ES023569 Nucleic Acids Res (2015Jul 13)
25990721
2015
Bypass of a 5',8-cyclopurine-2'-deoxynucleoside byDNA polymerase β during DNA replication and base...
Jiang, Zhongliang; Xu,Meng; Lai, Yanhao;Laverde, Eduardo E;Terzidis, Michael A;Masi, Annal ...
R01ES023569 DNA Repair (Amst) (2015Sep)
26123757
2015
Cdt2-mediated XPG degradation promotes gap-fillingDNA synthesis in nucleotide excision repair.
Han, Chunhua; Wani,Gulzar; Zhao, Ran;Qian, Jiang; Sharma,Nidhi; He, Jinshan;Zhu, Qianzhen ...
R01ES012991 Cell Cycle (2015) 25483071
2015
Characterization of Interstrand DNA-DNACross-Links Derived from Abasic Sites UsingBacteriophage ϕ2 ...
Yang, Zhiyu; Price,Nathan E; Johnson,Kevin M; Gates, Kent S
R01ES021007 Biochemistry (2015 Jul 14) 26103998
2015
Characterization of Interstrand DNA-DNACross-Links Using the α-Hemolysin Protein Nanopore.
Zhang, Xinyue; Price,Nathan E; Fang, Xi;Yang, Zhiyu; Gu,Li-Qun; Gates, Kent S
R01ES021007 ACS Nano (2015 Dec 22) 26563913
2015
Chemical and structural characterization of interstrandcross-links formed between abasic sites and ...
Price, Nathan E;Catalano, Michael J;Liu, Shuo; Wang,Yinsheng; Gates, KentS
R01ES021007 Nucleic Acids Res (2015Apr 20)
25779045
2015
Chemical structure and properties of interstrandcross-links formed by reaction of guanine residues ...
Catalano, Michael J;Liu, Shuo; Andersen,Nisana; Yang, Zhiyu;Johnson, Kevin M;Price, Nathan ...
R01ES021007 J Am Chem Soc (2015Mar 25)
25710271
2015
ChIP-Seq analysis of the adult male mouse brain afterdevelopmental exposure to arsenic.
Tyler, Christina R;Weber, Jessica A;Labrecque, Matthew;Hessinger, Justin M;Edwards, Jeremy ...
R01ES019583 Data Brief (2015 Dec) 26543888
2015
Colon cancer-associated mutator DNA polymerase δvariant causes expansion of dNTP pools increasing i ...
Mertz, Tony M;Sharma, Sushma;Chabes, Andrei;Shcherbakova, Polina V
R01ES015869 Proc Natl Acad Sci U S A(2015 May 12)
25827231
2015
Cytotoxic and mutagenic properties ofO4-alkylthymidine lesions in Escherichia coli cells.
Wang, Pengcheng;Amato, Nicholas J;Zhai, Qianqian; Wang,Yinsheng
R01ES025121 Nucleic Acids Res (2015Dec 15)
26400162
2015
Damaged DNA-binding protein down-regulatesepigenetic mark H3K56Ac through histone deacetylase1 and ...
Zhu, Qianzheng; Battu,Aruna; Ray, Alo; Wani,Gulzar; Qian, Jiang; He,Jinshan; Wang, Qi-en;...
R01ES012991 Mutat Res (2015 Jun) 26255936
2015
Developmental exposure to 50 parts-per-billion arsenicinfluences histone modifications and associat ...
Tyler, Christina R;Hafez, Alexander K;Solomon, Elizabeth R;Allan, Andrea M
R01ES019583 Toxicol Appl Pharmacol(2015 Oct 01)
26193056
2015
Distinct actions of ancestral vinclozolin and juvenilestress on neural gene expression in the male ...
Gillette, Ross;Miller-Crews, Isaac;Skinner, Michael K;Crews, David
R01ES012974,R01ES012974
Front Genet (2015) 25784924
2015
Disturbed flow induces systemic changes inmetabolites in mouse plasma: a metabolomics studyusing A ...
Go, Young-Mi; Kim,Chan Woo; Walker,Douglas I; Kang, DongWon; Kumar, Sandeep;Orr, Michael; ...
R01ES023485 Am J Physiol Regul IntegrComp Physiol (2015 Jan01)
25377480
2015
DNA double-strand breaks by Cr(VI) are targeted toeuchromatin and cause ATR-dependent phosphorylati...
DeLoughery, Zachary;Luczak, Michal W;Ortega-Atienza, Sara;Zhitkovich, Anatoly
R01ES008786 Toxicol Sci (2015 Jan) 25288669
2015
DNA polymerase ζ-dependent lesion bypass inSaccharomyces cerevisiae is accompanied byerror-prone c ...
Kochenova, Olga V;Daee, Danielle L;Mertz, Tony M;Shcherbakova, Polina V
R01ES015869 PLoS Genet (2015 Mar) 25826305
2015
DNA replication stress underlies renal phenotypes inCEP290-associated Joubert syndrome.
Slaats, Gisela G;Saldivar, Joshua C;Bacal, Julien; Zeman,Michelle K; Kile,Andrew C; Hynes, ...
R01ES016486 J Clin Invest (2015 Sep) 26301811
2015
DNA sequence alignment by microhomology samplingduring homologous recombination.
Qi, Zhi; Redding, Sy;Lee, Ja Yil; Gibb,Bryan; Kwon,YoungHo; Niu,Hengyao; Gaines,William ...
R01ES007061 Cell (2015 Feb 26) 25684365
2015
DNA-Protein Cross-Links: Formation, StructuralIdentities, and Biological Outcomes.
Tretyakova, Natalia Y;Groehler 4th, Arnold;Ji, Shaofei
R01ES023350 Acc Chem Res (2015 Jun16)
26032357
2015
Early programing of uterine tissue by bisphenol A:Critical evaluation of evidence from animal expos ...
Suvorov, Alexander;Waxman, David J
R01ES024421 Reprod Toxicol (2015Nov)
26028543
2015
Environmental Epigenetics and a Unified Theory ofthe Molecular Aspects of Evolution: A Neo-Lamarcki...
Skinner, Michael K R01ES012974,R01ES012974
Genome Biol Evol (2015May)
25917417
2015
Environmentally Induced EpigeneticTransgenerational Inheritance of Altered SRYGenomic Binding Duri ...
Skinner, Michael K;Bhandari, Ramji K;Haque, M Muksitul;Nilsson, Eric E
R01ES012974,R01ES012974
Environ Epigenet (2015Dec)
27175298
2015
Environmentally induced epigenetic transgenerationalinheritance of disease susceptibility.
Nilsson, Eric E;Skinner, Michael K
R01ES012974,R01ES012974
Transl Res (2015 Jan) 24657180
2015
Environmentally Induced EpigeneticTransgenerational Inheritance of ReproductiveDisease.
Nilsson, Eric E;Skinner, Michael K
R01ES012974,R01ES012974
Biol Reprod (2015 Dec) 26510870
2015
Environmentally induced epigenetic transgenerationalinheritance of sperm epimutations promote genet ...
Skinner, Michael K;Guerrero-Bosagna,Carlos; Haque, MMuksitul
R01ES012974,R01ES012974
Epigenetics (2015) 26237076
2015
Error-prone translesion synthesis past DNA-peptidecross-links conjugated to the major groove of DNA ...
Wickramaratne, Susith;Boldry, Emily J;Buehler, Charles;Wang, Yen-Chih;Distefano, Mark D; Tr...
R01ES023350 J Biol Chem (2015 Jan 9) 25391658
2015
Functions and regulation of the multitasking FANCMfamily of DNA motor proteins.
Xue, Xiaoyu; Sung,Patrick; Zhao, Xiaolan
R01ES007061 Genes Dev (2015 Sep 01) 26341555
2015
Genome-Wide Locations of Potential EpimutationsAssociated with Environmentally Induced EpigeneticT ...
Haque, M Muksitul;Holder, Lawrence B;Skinner, Michael K
R01ES012974,R01ES012974
PLoS One (2015) 26571271
2015
Genome-Wide Profiling of PARP1 Reveals anInterplay with Gene Regulatory Regions and DNAMethylation ...
Nalabothula,Narasimharao;Al-jumaily, Taha;Eteleeb, Abdallah M;Flight, Robert M;Xiaorong, S ...
R01ES024478 PLoS One (2015) 26305327
2015
Heterozygosity for a hypomorphic Polβ mutationreduces the expansion frequency in a mouse model of t...
Lokanga, Rachel Adihe;Senejani, AlirezaGhodsi; Sweasy, JoannBalazs; Usdin, Karen
R01ES019179 PLoS Genet (2015 Apr) 25886163
2015
High-throughput screening-compatible assays ofAs(III) S-adenosylmethionine methyltransferase activi...
Dong, Hui; Xu,Wenzhong; Pillai,Jitesh K; Packianathan,Charles; Rosen, Barry P
R01ES023779 Anal Biochem (2015 Jul01)
25866076
2015
HLTF's Ancient HIRAN Domain Binds 3' DNA Endsto Drive Replication Fork Reversal.
Kile, Andrew C;Chavez, Diana A;Bacal, Julien; Eldirany,Sherif; Korzhnev,Dmitry M; Bezsonova...
R01ES016486 Mol Cell (2015 Jun 18) 26051180
2015
Human DNA ligase III bridges two DNA ends topromote specific intermolecular DNA end joining.
Kukshal, Vandna; Kim,In-Kwon; Hura,Gregory L; Tomkinson,Alan E; Tainer, John A;Ellenberger, ...
R01ES012512 Nucleic Acids Res (2015Aug 18)
26130724
2015
Identification of Small Molecule Inhibitors of HumanAs(III) S-Adenosylmethionine Methyltransferase ...
Dong, Hui;Madegowda, Mahendra;Nefzi, Adel; Houghten,Richard A; Giulianotti,Marc A; Rosen, ...
R01ES023779 Chem Res Toxicol (2015Dec 21)
26577531
2015
Inorganic Arsenic-induced cellular transformation iscoupled with genome wide changes in chromatin s ...
Riedmann, Caitlyn; Ma,Ye; Melikishvili,Manana; Godfrey,Steven Grason; Zhang,Zhou; Chen, Ku ...
R01ES024478 BMC Genomics (2015) 25879800
2015
Linker histone H1 and H3K56 acetylation areantagonistic regulators of nucleosome dynamics.
Bernier, Morgan; Luo,Yi; Nwokelo, KingsleyC; Goodwin, Michelle;Dreher, Sarah J; Zhang,Pei; ...
R01ES024478 Nat Commun (2015) 26648124
2015
LKB1 preserves genome integrity by stimulatingBRCA1 expression.
Gupta, Romi; Liu, AlexY; Glazer, Peter M;Wajapeyee, Narendra
R01ES005775 Nucleic Acids Res (2015Jan)
25488815
2015
Low-Dose Cadmium Causes Metabolic and GeneticDysregulation Associated With Fatty Liver Disease inM ...
Go, Young-Mi; Sutliff,Roy L; Chandler,Joshua D; Khalidur,Rahman; Kang,Bum-Yong; Anania, Fr...
P30ES019776,R01ES023485,T32ES012870
Toxicol Sci (2015 Oct) 26187450
2015
Markov counting models for correlated binaryresponses.
Crawford, Forrest W;Zelterman, Daniel
R01ES005775 Biostatistics (2015 Jul) 25792624
2015
Mass spectrometry for the assessment of theoccurrence and biological consequences of DNAadducts.
Liu, Shuo; Wang,Yinsheng
R01ES021007 Chem Soc Rev (2015 Nov7)
26204249
2015
Mechanism of action studies of lomaiviticin A and themonomeric lomaiviticin aglycon. Selective and ...
Colis, Laureen C;Hegan, Denise C;Kaneko, Miho; Glazer,Peter M; Herzon, SethB
R01ES005775 J Am Chem Soc (2015May 6)
25849366
2015
Metabolic Characterization of the Common Marmoset(Callithrix jacchus).
Go, Young-Mi; Liang,Yongliang; Uppal,Karan; Soltow, QuinlynA; Promislow, Daniel EL; Wachtma ...
P30ES019776,R01ES023485,T32ES012870
PLoS One (2015) 26581102
2015
Metabolome-wide association study of phenylalaninein plasma of common marmosets.
Go, Young-Mi; Walker,Douglas I; Soltow,Quinlyn A; Uppal,Karan; Wachtman,Lynn M; Strobel, F ...
P30ES019776,R01ES023485,T32ES012870
Amino Acids (2015 Mar) 25526869
2015
Metabolome-Wide Association Study of Primary OpenAngle Glaucoma.
Burgess, L Goodwin;Uppal, Karan; Walker,Douglas I; Roberson,Rachel M; Tran,ViLinh; Parks, ...
P30ES019776,R01ES023485,T32ES012870
Invest Ophthalmol Vis Sci(2015 Jul)
26230767
2015
MicroRNA silencing for cancer therapy targeted to thetumour microenvironment.
Cheng, Christopher J;Bahal, Raman; Babar,Imran A; Pincus,Zachary; Barrera,Francisco; Liu, ...
R01ES005775 Nature (2015 Feb 5) 25409146
2015
Mimicking Ribosomal Unfolding of RNA Pseudoknotin a Protein Channel.
Zhang, Xinyue; Xu,Xiaojun; Yang, Zhiyu;Burcke, Andrew J;Gates, Kent S; Chen,Shi-Jie; Gu, ...
R01ES021007 J Am Chem Soc (2015Dec 23)
26595106
2015
Mitochondrial Single-stranded DNA-binding ProteinsStimulate the Activity of DNA Polymerase γ by Org ...
Ciesielski, Grzegorz L;Bermek, Oya;Rosado-Ruiz, FernandoA; Hovde, Stacy L;Neitzke, Orrin J; ...
R56ES013773 J Biol Chem (2015 Nov27)
26446790
2015
Multifaceted control of DNA repair pathways by thehypoxic tumor microenvironment.
Scanlon, Susan E;Glazer, Peter M
R01ES005775 DNA Repair (Amst) (2015Aug)
25956861
2015
Obesity, diabetes, and associated costs of exposure toendocrine-disrupting chemicals in the Europea ...
Legler, Juliette;Fletcher, Tony;Govarts, Eva; Porta,Miquel; Blumberg,Bruce; Heindel, Jerro ...
R01ES023316,R01ES023316
J Clin Endocrinol Metab(2015 Apr)
25742518
2015
Origin and development of neuropil glia of theDrosophila larval and adult brain: Two distinct glial ...
Omoto, Jaison Jiro;Yogi, Puja; Hartenstein,Volker
R01ES029357 Dev Biol (2015 Aug 15) 25779704
2015
Parma consensus statement on metabolic disruptors. Heindel, Jerrold J; VomSaal, Frederick S;Blumberg, Bruce;Bovolin, Patrizia;Calamandrei, Gem ...
R01ES023316,R01ES023316
Environ Health (2015 0620)
26092037
2015
Prenatal arsenic exposure alters the programming ofthe glucocorticoid signaling system during embry ...
Caldwell, Katharine E;Labrecque, Matthew T;Solomon, Benjamin R;Ali, Abdulmehdi; Allan,Andre ...
R01ES019583 Neurotoxicol Teratol (2015Jan-Feb)
25459689
2015
Promotion of BRCA2-Dependent HomologousRecombination by DSS1 via RPA Targeting and DNAMimicry.
Zhao, Weixing;Vaithiyalingam,Sivaraja; San Filippo,Joseph; Maranon, DavidG; Jimenez-Sainz, ...
R01ES007061 Mol Cell (2015 Jul 16) 26145171
2015
Promotion of presynaptic filament assembly by theensemble of S. cerevisiae Rad51 paralogues with Ra ...
Gaines, William A;Godin, Stephen K;Kabbinavar, Faiz F;Rao, Timsi;VanDemark, Andrew P;Sung, ...
R01ES007061 Nat Commun (2015) 26215801
2015
Quantitative measurement of transcriptional inhibitionand mutagenesis induced by site-specifically ...
You, Changjun; Wang,Yinsheng
R01ES025121 Nat Protoc (2015 Sep) 26292071
2015
Redox theory of aging. Jones, Dean P P30ES019776,R01ES023485,T32ES012870
Redox Biol (2015 Aug) 25863726
2015
Reference Standardization for Mass Spectrometry andHigh-resolution Metabolomics Applications to Exp ...
Go, Young-Mi; Walker,Douglas I; Liang,Yongliang; Uppal,Karan; Soltow, QuinlynA; Tran, ViLi ...
P30ES019776,R01ES023485,T32ES012870
Toxicol Sci (2015 Dec) 26358001
2015
Resveratrol protects against arsenic trioxide-inducedoxidative damage through maintenance of glutat ...
Chen, Chengzhi; Jiang,Xuejun; Lai, Yanhao;Liu, Yuan; Zhang,Zunzhen
R01ES023569 Environ Mol Mutagen(2015 Apr)
25339131
2015
Rev1 promotes replication through UV lesions inconjunction with DNA polymerases η, ι, and κ but not...
Yoon, Jung-Hoon; Park,Jeseong; Conde, Juan;Wakamiya, Maki;Prakash, Louise;Prakash, Satya
R01ES022948 Genes Dev (2015 Dec 15) 26680302
2015
Role of mismatch repair proteins in the processing ofcisplatin interstrand cross-links.
Sawant, Akshada;Kothandapani,Anbarasi; Zhitkovich,Anatoly; Sobol, RobertW; Patrick, Steve M
R01ES008786 DNA Repair (Amst) (2015Nov)
26519826
2015
Selective modulation of the functions of a conservedDNA motor by a histone fold complex.
Xue, Xiaoyu; Choi,Koyi; Bonner, Jaclyn N;Szakal, Barnabas; Chen,Yu-Hung; Papusha,Alma; Sar ...
R01ES007061 Genes Dev (2015 May 15) 25956905
2015
Sex-Dependent effects of developmental arsenicexposure on methylation capacity and methylation regu...
Allan, Andrea M;Hafez, Alexander K;Labrecque, Matthew T;Solomon, Elizabeth R;Shaikh, M Nabi ...
R01ES019583 Toxicol Rep (2015 Oct) 26855884
2015
Significance of ligand interactions involvingHop2-Mnd1 and the RAD51 and DMC1 recombinasesin homol ...
Zhao, Weixing; Sung,Patrick
R01ES007061 Nucleic Acids Res (2015Apr 30)
25820426
2015
Synthesis of DNA Oligodeoxynucleotides ContainingSite-Specific 1,3-Butadiene-Deoxyadenosine Lesions...
Wickramaratne, Susith;Seiler, Christopher L;Tretyakova, Natalia Y
R01ES023350 Curr Protoc Nucleic AcidChem (2015 Jun 03)
26344227
2015
Synthetic viability genomic screening defines Sae2function in DNA repair.
Puddu, Fabio;Oelschlaegel, Tobias;Guerini, Ilaria; Geisler,Nicola J; Niu, Hengyao;Herzog, ...
R01ES007061 EMBO J (2015 Jun 03) 25899817
2015
The cysteine proteome. Go, Young-Mi;Chandler, Joshua D;Jones, Dean P
P30ES019776,R01ES023485,T32ES012870
Free Radic Biol Med (2015Jul)
25843657
2015
The Redox Code. Jones, Dean P; Sies,Helmut
P30ES019776,R01ES023485,T32ES012870
Antioxid Redox Signal(2015 Sep 20)
25891126
2015
Tumor suppressor p53 stole the AKT in hypoxia. Yun, Zhong; Glazer,Peter M
R01ES005775 J Clin Invest (2015 Jun) 25961449
2015
USP7 deubiquitinase promotes ubiquitin-dependentDNA damage signaling by stabilizing RNF168.
Zhu, Qianzheng;Sharma, Nidhi; He,Jinshan; Wani, Gulzar;Wani, Altaf A
R01ES012991 Cell Cycle (2015) 25894431
2015
USP7 modulates UV-induced PCNAmonoubiquitination by regulating DNA polymeraseeta stability.
Qian, J; Pentz, K; Zhu,Q; Wang, Q; He, J;Srivastava, A K; Wani,A A
R01ES012991 Oncogene (2015 Sep 03) 25435364
2015
A 5', 8-cyclo-2'-deoxypurine lesion inducestrinucleotide repeat deletion via a unique lesion bypass...
Xu, Meng; Lai, Yanhao;Jiang, Zhongliang;Terzidis, Michael A;Masi, Annalisa;Chatgilialoglu, ...
R01ES023569 Nucleic Acids Res (2014Dec 16)
25428354
2014
A common cancer-associated DNA polymerase εmutation causes an exceptionally strong mutatorphenotyp ...
Kane, Daniel P;Shcherbakova, Polina V
R01ES015869 Cancer Res (2014 Apr 1) 24525744
2014
A new kind of inheritance. Skinner, Michael K R01ES012974,R01ES012974
Sci Am (2014 Aug) 25095468
2014
A recombinant reporter system for monitoringreactivation of an endogenously DNAhypermethylated gen ...
Cui, Ying; Hausheer,Frederick; Beaty,Robert; Zahnow,Cynthia; Issa, JeanPierre; Bunz, Frede ...
R01ES011858 Cancer Res (2014 Jul 15) 24876104
2014
Amplified single base-pair mismatch detection viaaggregation of exonuclease-sheared gold nanopartic ...
Wu, Shuo; Liang,Pingping; Yu, Haixiang;Xu, Xiaowen; Liu,Yuan; Lou, Xinhui;Xiao, Yi
R01ES023569 Anal Chem (2014 Apr 1) 24611947
2014
Avoidance of ribonucleotide-induced mutations byRNase H2 and Srs2-Exo1 mechanisms.
Potenski, Catherine J;Niu, Hengyao; Sung,Patrick; Klein, HannahL
R01ES007061 Nature (2014 Jul 10) 24896181
2014
Base excision repair of chemotherapeutically-inducedalkylated DNA damage predominantly causes contr ...
Lai, Yanhao; Beaver,Jill M; Lorente, Karla;Melo, Jonathan;Ramjagsingh, Shyama;Agoulnik, Ir ...
R01ES023569 PLoS One (2014) 24691413
2014
Base excision repair of oxidative DNA damagecoupled with removal of a CAG repeat hairpinattenuates ...
Xu, Meng; Lai, Yanhao;Torner, Justin; Zhang,Yanbin; Zhang,Zunzhen; Liu, Yuan
R01ES023569 Nucleic Acids Res (2014Apr)
24423876
2014
Cancer epigenetics: tumor heterogeneity, plasticity ofstem-like states, and drug resistance.
Easwaran, Hariharan;Tsai, Hsing-Chen;Baylin, Stephen B
R01ES011858 Mol Cell (2014 Jun 5) 24905005
2014
Causes and consequences of replication stress. Zeman, Michelle K;Cimprich, Karlene A
R01ES016486 Nat Cell Biol (2014 Jan) 24366029
2014
Chromosomal translocations in human cells aregenerated by canonical nonhomologous end-joining.
Ghezraoui, Hind;Piganeau, Marion;Renouf, Benjamin;Renaud, Jean-Baptiste;Sallmyr, Annahita; ...
R01ES012512 Mol Cell (2014 Sep 18) 25201414
2014
Concentration-dependent exchange of replicationprotein A on single-stranded DNA revealed by single-...
Gibb, Bryan; Ye, LingF; Gergoudis, StephanieC; Kwon, YoungHo;Niu, Hengyao; Sung,Patrick; G ...
R01ES007061 PLoS One (2014) 24498402
2014
Conditional inactivation of Miwi2 reveals that MIWI2is only essential for prospermatogonial develop ...
Bao, J; Zhang, Y;Schuster, A S;Ortogero, N; Nilsson, EE; Skinner, M K; Yan,W
R01ES012974,R01ES012974
Cell Death Differ (2014May)
24464225
2014
Covalent adduct formation between theantihypertensive drug hydralazine and abasic sites indouble- ...
Melton, Douglas;Lewis, Calvin D; Price,Nathan E; Gates, Kent S
R01ES021007 Chem Res Toxicol (2014Dec 15)
25405892
2014
Cytokine (IL16) and tyrphostin actions on ovarianprimordial follicle development.
Feeney, Amanda;Nilsson, Eric; Skinner,Michael K
R01ES012974,R01ES012974
Reproduction (2014 Sep) 24970835
2014
DDT, epigenetic harm, and transgenerationalenvironmental justice.
Kabasenche, William P;Skinner, Michael K
R01ES012974,R01ES012974
Environ Health (2014 Aug02)
25086599
2014
Disturbed flow enhances inflammatory signaling andatherogenesis by increasing thioredoxin-1 level i ...
Go, Young-Mi; Son,Dong Ju; Park,Heonyong; Orr,Michael; Hao, Li;Takabe, Wakako;Kumar, San ...
R01ES023485 PLoS One (2014) 25265386
2014
DNA damage-binding complex recruits HDAC1 torepress Bcl-2 transcription in human ovarian cancercel ...
Zhao, Ran; Han,Chunhua; Eisenhauer,Eric; Kroger, John;Zhao, Weiqiang; Yu,Jianhua; Selvendi ...
R01ES012991 Mol Cancer Res (2014Mar)
24249678
2014
DNA damage-specific deubiquitination regulatesRad18 functions to suppress mutagenesis.
Zeman, Michelle K;Lin, Jia-Ren; Freire,Raimundo; Cimprich,Karlene A
R01ES016486 J Cell Biol (2014 Jul 21) 25023518
2014
DNA polymerases ζ and Rev1 mediate error-pronebypass of non-B DNA structures.
Northam, Matthew R;Moore, Elizabeth A;Mertz, Tony M; Binz,Sara K; Stith, Carrie M;Stepchenk ...
R01ES015869 Nucleic Acids Res (2014Jan)
24049079
2014
Down-regulation of Rad51 activity during meiosis inyeast prevents competition with Dmc1 for repair ...
Liu, Yan; Gaines,William A; Callender,Tracy; Busygina,Valeria; Oke, Ashwini;Sung, Patrick; ...
R01ES007061 PLoS Genet (2014 Jan) 24465215
2014
Earth Abides Arsenic Biotransformations. Zhu, Yong-Guan;Yoshinaga, Masafumi;Zhao, Fang-Jie; Rosen,Barry P
R01ES023779 Annu Rev Earth Planet Sci(2014 May 01)
26778863
2014
Endocrine disruptor induction of epigenetictransgenerational inheritance of disease.
Skinner, Michael K R01ES012974,R01ES012974
Mol Cell Endocrinol (2014Dec)
25088466
2014
Environment, epigenetics and reproduction. Skinner, Michael K R01ES012974,R01ES012974
Mol Cell Endocrinol (2014Dec)
25086400
2014
Environmental epigenetics andphytoestrogen/phytochemical exposures.
Guerrero-Bosagna,Carlos M; Skinner,Michael K
R01ES012974,R01ES012974
J Steroid Biochem MolBiol (2014 Jan)
23274117
2014
Environmental stress and epigenetic transgenerationalinheritance.
Skinner, Michael K R01ES012974,R01ES012974
BMC Med (2014 Sep 05) 25259699
2014
Environmentally induced epigenetic transgenerationalinheritance of male infertility.
Guerrero-Bosagna,Carlos; Skinner,Michael K
R01ES012974,R01ES012974
Curr Opin Genet Dev(2014 Jun)
25104619
2014
Epigenetics and the evolution of Darwin's Finches. Skinner, Michael K;Gurerrero-Bosagna,Carlos; Haque, MMuksitul; Nilsson, EricE; Koop, Jennif ...
R01ES012974,R01ES012974
Genome Biol Evol (2014Aug)
25062919
2014
Expression of the p12 subunit of human DNApolymerase δ (Pol δ), CDK inhibitor p21(WAF1),Cdt1, cycl ...
Zhao, Hong; Zhang,Sufang; Xu, Dazhong;Lee, Marietta Ywt;Zhang, Zhongtao; Lee,Ernest Yc; Da ...
R56ES014737 Cell Cycle (2014) 25483089
2014
Fluoxetine treatment ameliorates depression inducedby perinatal arsenic exposure via a neurogenic m ...
Tyler, Christina R;Solomon, Benjamin R;Ulibarri, Adam L;Allan, Andrea M
R01ES019583 Neurotoxicology (2014Sep)
24952232
2014
Gene bionetworks involved in the epigenetictransgenerational inheritance of altered matepreference ...
Skinner, Michael K;Savenkova, Marina I;Zhang, Bin; Gore,Andrea C; Crews,David
R01ES012974,R01ES012974
BMC Genomics (2014) 24885959
2014
Harnessing the potential of epigenetic therapy to targetsolid tumors.
Ahuja, Nita; Easwaran,Hariharan; Baylin,Stephen B
R01ES011858 J Clin Invest (2014 Jan) 24382390
2014
Hypoxic stress facilitates acute activation and chronicdownregulation of fanconi anemia proteins.
Scanlon, Susan E;Glazer, Peter M
R01ES005775 Mol Cancer Res (2014 Jul) 24688021
2014
Identification of genomic features in environmentallyinduced epigenetic transgenerational inherited ...
Guerrero-Bosagna,Carlos; Weeks, Shelby;Skinner, Michael K
R01ES012974,R01ES012974
PLoS One (2014) 24937757
2014
Imbalanced class learning in epigenetics. Haque, M Muksitul;Skinner, Michael K;Holder, Lawrence B
R01ES012974,R01ES012974
J Comput Biol (2014 Jul) 24798423
2014
Interplay between DNA repair and inflammation, andthe link to cancer.
Kidane, Dawit; Chae,Wook Jin; Czochor,Jennifer; Eckert, KristinA; Glazer, Peter M;Bothwell, ...
R01ES019179 Crit Rev Biochem MolBiol (2014 Mar-Apr)
24410153
2014
Interstrand DNA-DNA cross-link formation betweenadenine residues and abasic sites in duplex DNA.
Price, Nathan E;Johnson, Kevin M;Wang, Jin; Fekry,Mostafa I; Wang,Yinsheng; Gates, KentS
R01ES021007 J Am Chem Soc (2014Mar 5)
24506784
2014
Mechanistic insights into the role of Hop2-Mnd1 inmeiotic homologous DNA pairing.
Zhao, Weixing; Saro,Dorina; Hammel,Michal; Kwon,Youngho; Xu,Yuanyuan; Rambo,Robert P; Wil ...
R01ES007061 Nucleic Acids Res (2014Jan)
24150939
2014
Mitochondrial metabolomics using high-resolutionFourier-transform mass spectrometry.
Go, Young-Mi; Uppal,Karan; Walker, DouglasI; Tran, ViLinh; Dury,Lauriane; Strobel,Frederic ...
R01ES023485,T32ES012870
Methods Mol Biol (2014) 25270922
2014
Monitoring Cr intermediates and reactive oxygenspecies with fluorescent probes during chromate redu...
DeLoughery, Zachary;Luczak, Michal W;Zhitkovich, Anatoly
R01ES008786 Chem Res Toxicol (2014May 19)
24646070
2014
Mutation of POLB causes lupus in mice. Senejani, Alireza G;Liu, Yanfeng; Kidane,Dawit; Maher, StephenE; Zeiss, Caroline J;Park, H ...
R01ES019179 Cell Rep (2014 Jan 16) 24388753
2014
Nature, nurture and epigenetics. Crews, David; Gillette,Ross; Miller-Crews,Isaac; Gore, Andrea C;Skinner, Michael K
R01ES012974,R01ES012974
Mol Cell Endocrinol (2014Dec)
25102229
2014
Pathway of human AS3MT arsenic methylation. Dheeman, DharmendraS; Packianathan,Charles; Pillai, Jitesh K;Rosen, Barry P
R01ES023779 Chem Res Toxicol (2014Nov 17)
25325836
2014
Pesticide methoxychlor promotes the epigenetictransgenerational inheritance of adult-onset disease ...
Manikkam, Mohan;Haque, M Muksitul;Guerrero-Bosagna,Carlos; Nilsson, Eric E;Skinner, Michael ...
R01ES012974,R01ES012974
PLoS One (2014) 25057798
2014
Protein dynamics during presynaptic-complexassembly on individual single-stranded DNAmolecules.
Gibb, Bryan; Ye, LingF; Kwon, YoungHo;Niu, Hengyao; Sung,Patrick; Greene, Eric C
R01ES007061 Nat Struct Mol Biol (2014Oct)
25195049
2014
Replicative bypass of abasic site in Escherichia coliand human cells: similarities and differences.
Weerasooriya, Savithri;Jasti, Vijay P; Basu,Ashis K
R01ES021762,R01ES023350
PLoS One (2014) 25226389
2014
Response to the letter to the editor regarding our article(Dheeman et al., 2014).
Dheeman, DharmendraS; Packianathana,Charles; Pillai, Jitesh K;Rosen, Barry P
R01ES023779 Chem Res Toxicol (2014Dec 15)
25383697
2014
Restriction of replication fork regression activities by aconserved SMC complex.
Xue, Xiaoyu; Choi,Koyi; Bonner, Jaclyn;Chiba, Tamara; Kwon,Youngho; Xu,Yuanyuan; Sanchez, ...
R01ES007061 Mol Cell (2014 Nov 6) 25439736
2014
Role of CpG deserts in the epigenetic transgenerationalinheritance of differential DNA methylation ...
Skinner, Michael K;Guerrero-Bosagna,Carlos
R01ES012974,R01ES012974
BMC Genomics (2014) 25142051
2014
Roles of Gremlin 1 and Gremlin 2 in regulatingovarian primordial to primary follicle transition.
Nilsson, Eric E; Larsen,Ginger; Skinner,Michael K
R01ES012974,R01ES012974
Reproduction (2014 Jun) 24614542
2014
Sexually dimorphic effects of ancestral exposure tovinclozolin on stress reactivity in rats.
Gillette, Ross;Miller-Crews, Isaac;Nilsson, Eric E;Skinner, Michael K;Gore, Andrea C; Crews...
R01ES012974,R01ES012974
Endocrinology (2014 Oct) 25051444
2014
Silencing of the DNA mismatch repair gene MLH1induced by hypoxic stress in a pathway dependent on t...
Lu, Yuhong;Wajapeyee, Narendra;Turker, Mitchell S;Glazer, Peter M
R01ES005775 Cell Rep (2014 Jul 24) 25043185
2014
Structural and functional conservation of fungal MatAand human SRY sex-determining proteins.
Czaja, Wioletta; Miller,Karen Y; Skinner,Michael K; Miller,Bruce L
R01ES012974,R01ES012974
Nat Commun (2014) 25399555
2014
Syntheses and characterizations of the in vivoreplicative bypass and mutagenic properties of the mi...
Zhai, Qianqian; Wang,Pengcheng; Cai, Qian;Wang, Yinsheng
R01ES025121 Nucleic Acids Res (2014) 25120272
2014
The cytotoxicity of (-)-lomaiviticin A arises frominduction of double-strand breaks in DNA.
Colis, Laureen C; Woo,Christina M; Hegan,Denise C; Li, Zhenwu;Glazer, Peter M;Herzon, Seth ...
R01ES005775 Nat Chem (2014 Jun) 24848236
2014
The Effects of Arsenic Exposure on Neurological andCognitive Dysfunction in Human and Rodent Studie ...
Tyler, Christina R;Allan, Andrea M
R01ES019583 Curr Environ Health Rep(2014)
24860722
2014
The NuRD complex cooperates with DNMTs tomaintain silencing of key colorectal tumor suppressorgene ...
Cai, Y; Geutjes, E-J; deLint, K; Roepman, P;Bruurs, L; Yu, L-R;Wang, W; vanBlijswijk, J; ...
R01ES011858 Oncogene (2014 Apr 24) 23708667
2014
The S229L colon tumor-associated variant of DNApolymerase β induces cellular transformation as a re ...
Nemec, Antonia A;Murphy, Drew L;Donigan, Katherine A;Sweasy, Joann B
R01ES019179 J Biol Chem (2014 May16)
24668809
2014
The tail that wags the dog: p12, the smallest subunit ofDNA polymerase δ, is degraded by ubiquitin ...
Lee, Marietta Y W T;Zhang, Sufang; Lin, SzuHua Sharon; Wang,Xiaoxiao;Darzynkiewicz, Zbignie...
R56ES014737 Cell Cycle (2014) 24300032
2014
Toward hypoxia-selective DNA-alkylating agents builtby grafting nitrogen mustards onto the bioreduc ...
Johnson, Kevin M;Parsons, Zachary D;Barnes, Charles L;Gates, Kent S
R01ES021007 J Org Chem (2014 Aug 15) 25029663
2014
Transcriptional bypass of regioisomeric ethylatedthymidine lesions by T7 RNA polymerase and humanR ...
You, Changjun; Wang,Pengcheng; Dai,Xiaoxia; Wang,Yinsheng
R01ES025121 Nucleic Acids Res (2014Dec 16)
25404131
2014
Transcriptome-metabolome wide association study(TMWAS) of maneb and paraquat neurotoxicityreveals ...
Roede, James R; Uppal,Karan; Park, Youngja;Tran, ViLinh; Jones,Dean P
P30ES019776,R01ES023485
Toxicol Rep (2014) 27722094
2014
Transgenerational effects of obesogens and the obesityepidemic.
Chamorro-García,Raquel; Blumberg,Bruce
R01ES023316,R01ES023316
Curr Opin Pharmacol(2014 Dec)
25460228
2014
Transgenerational inheritance of prenatal obesogenexposure.
Janesick, Amanda S;Shioda, Toshihiro;Blumberg, Bruce
R01ES023316,R01ES023316
Mol Cell Endocrinol (2014Dec)
25218215
2014
Ubiquitin-specific protease 7 regulates nucleotideexcision repair through deubiquitinating XPC prot ...
He, Jinshan; Zhu,Qianzheng; Wani,Gulzar; Sharma, Nidhi;Han, Chunhua; Qian,Jiang; Pentz, K ...
R01ES012991 J Biol Chem (2014 Sep 26) 25118285
2014
USP3 counteracts RNF168 via deubiquitinating H2Aand γH2AX at lysine 13 and 15.
Sharma, Nidhi; Zhu,Qianzheng; Wani,Gulzar; He, Jingshan;Wang, Qi-en; Wani,Altaf A
R01ES012991 Cell Cycle (2014) 24196443
2014
A quantitative mass spectrometry-based approach forassessing the repair of 8-methoxypsoralen-induce ...
Liu, Shuo; Wang,Yinsheng
R01ES021007 Anal Chem (2013 Jul 16) 23789926
2013
A reversible histone H3 acetylation cooperates withmismatch repair and replicative polymerases in m ...
Kadyrova, Lyudmila Y;Mertz, Tony M; Zhang,Yu; Northam, MatthewR; Sheng, Ziwei;Lobachev, Ki ...
R01ES015869 PLoS Genet (2013 Oct) 24204308
2013
A role for the MRN complex in ATR activation viaTOPBP1 recruitment.
Duursma, Anja M;Driscoll, Robert; Elias,Josh E; Cimprich,Karlene A
R01ES016486 Mol Cell (2013 Apr 11) 23582259
2013
Adult hippocampal neurogenesis and mRNAexpression are altered by perinatal arsenic exposure inmice ...
Tyler, Christina R;Allan, Andrea M
R01ES019583 PLoS One (2013) 24019935
2013
ATR phosphorylates SMARCAL1 to preventreplication fork collapse.
Couch, Frank B;Bansbach, Carol E;Driscoll, Robert;Luzwick, Jessica W;Glick, Gloria G; Bétou...
R01ES016486,T32ES007028
Genes Dev (2013 Jul 15) 23873943
2013
Caspase-2 short isoform interacts withmembrane-associated cytoskeleton proteins to inhibitapoptosi ...
Han, Chunhua; Zhao,Ran; Kroger, John; Qu,Meihua; Wani, Altaf A;Wang, Qi-En
R01ES012991 PLoS One (2013) 23840868
2013
Cellular roles of DNA polymerase beta. Ray, Sreerupa;Menezes, Miriam Rose;Senejani, Alireza;Sweasy, Joann B
R01ES019179 Yale J Biol Med (2013Dec 13)
24348210
2013
Chromium(VI) causes interstrand DNA cross-linkingin vitro but shows no hypersensitivity in cross-li ...
Morse, Jessica L;Luczak, Michal W;Zhitkovich, Anatoly
R01ES008786 Chem Res Toxicol (2013Oct 21)
24059640
2013
Cognitive function and breast cancer: promise andpotential insights from functional brain imaging.
Reuter-Lorenz, PatriciaA; Cimprich, Bernadine
R01ES016486 Breast Cancer Res Treat(2013 Jan)
23053652
2013
DNA ligases as therapeutic targets. Tomkinson, Alan E;Howes, Timothy R L;Wiest, Nathaniel E
R01ES012512 Transl Cancer Res (2013Jun)
24224145
2013
Dynamics of enzymatic interactions during short flaphuman Okazaki fragment processing by two forms ...
Lin, Szu Hua Sharon;Wang, Xiaoxiao;Zhang, Sufang; Zhang,Zhongtao; Lee, ErnestY C; Lee, Mar ...
R56ES014737 DNA Repair (Amst) (2013Nov)
24035200
2013
Epigenetic abnormalities in cancer find a "home on therange".
Easwaran, Hariharan;Baylin, Stephen B
R01ES011858 Cancer Cell (2013 Jan 14) 23328477
2013
Functional attributes of the Saccharomyces cerevisiaemeiotic recombinase Dmc1.
Busygina, Valeria;Gaines, William A; Xu,Yuanyuan; Kwon,Youngho; Williams,Gareth J; Lin, Sh ...
R01ES007061 DNA Repair (Amst) (2013Sep)
23769192
2013
Hydrocarbons (jet fuel JP-8) induce epigenetictransgenerational inheritance of obesity, reproductiv ...
Tracey, Rebecca;Manikkam, Mohan;Guerrero-Bosagna,Carlos; Skinner,Michael K
R01ES012974,R01ES012974
Reprod Toxicol (2013 Apr) 23453003
2013
Hypoxia and DNA repair. Glazer, Peter M; Hegan,Denise C; Lu, Yuhong;Czochor, Jennifer;Scanlon, Susan E
R01ES005775 Yale J Biol Med (2013Dec 13)
24348208
2013
NEK8 links the ATR-regulated replication stressresponse and S phase CDK activity to renal ciliopath ...
Choi, Hyo Jei Claudia;Lin, Jia-Ren; Vannier,Jean-Baptiste; Slaats,Gisela G; Kile, AndrewC; ...
R01ES016486 Mol Cell (2013 Aug 22) 23973373
2013
NER initiation factors, DDB2 and XPC, regulate UVradiation response by recruiting ATR and ATM kinas...
Ray, Alo; Milum,Keisha; Battu, Aruna;Wani, Gulzar; Wani,Altaf A
R01ES012991 DNA Repair (Amst) (2013Apr 01)
23422745
2013
Novel methylation biomarker panel for the earlydetection of pancreatic cancer.
Yi, Joo Mi; Guzzetta,Angela A; Bailey,Vasudev J; Downing,Stephanie R; VanNeste, Leander; Ch ...
R01ES011858 Clin Cancer Res (2013Dec 01)
24088737
2013
Nucleosome dynamics regulates DNA processing. Adkins, Nicholas L;Niu, Hengyao; Sung,Patrick; Peterson, CraigL
R01ES007061 Nat Struct Mol Biol (2013Jul)
23728291
2013
On the formation and properties of interstrandDNA-DNA cross-links forged by reaction of an abasics ...
Johnson, Kevin M;Price, Nathan E; Wang,Jin; Fekry, Mostafa I;Dutta, Sanjay; Seiner,Derrick ...
R01ES021007 J Am Chem Soc (2013 Jan23)
23215239
2013
p38 MAPK- and Akt-mediated p300 phosphorylationregulates its degradation to facilitate nucleotide e ...
Wang, Qi-En; Han,Chunhua; Zhao, Ran;Wani, Gulzar; Zhu,Qianzheng; Gong, Li;Battu, Aruna; R ...
R01ES012991 Nucleic Acids Res (2013Feb 01)
23275565
2013
p53 activation by Ni(II) is a HIF-1α independentresponse causing caspases 9/3-mediated apoptosis in ...
Wong, Victor C; Morse,Jessica L; Zhitkovich,Anatoly
P42ES013660,R01ES008786
Toxicol Appl Pharmacol(2013 Jun 15)
23566959
2013
PDIP38 is translocated to the spliceosomes/nuclearspeckles in response to UV-induced DNA damage and...
Wong, Agnes; Zhang,Sufang; Mordue, Dana;Wu, Joseph M; Zhang,Zhongtao;Darzynkiewicz, Zbigni...
R56ES014737 Cell Cycle (2013 Oct 01) 23989611
2013
PHD domain from human SHPRH. Machado, Luciana E F;Pustovalova, Yulia;Kile, Andrew C;Pozhidaeva, Alexandra;Cimprich, Karl ...
R01ES016486 J Biomol NMR (2013Aug)
23907177
2013
Pif1 helicase and Polýý promoterecombination-coupled DNA synthesis via bubblemigration.
Wilson, Marenda A;Kwon, YoungHo; Xu,Yuanyuan; Chung,Woo-Hyun; Chi, Peter;Niu, Hengyao; May ...
R01ES007061 Nature (2013 Oct 17) 24025768
2013
Postembryonic lineages of the Drosophila brain: I.Development of the lineage-associated fiber tract ...
Lovick, Jennifer K;Ngo, Kathy T; Omoto,Jaison J; Wong, DarrenC; Nguyen, Joseph D;Hartenstei ...
R01ES029357 Dev Biol (2013 Dec 15) 23880429
2013
RIF1 in DNA break repair pathway choice. Daley, James M; Sung,Patrick
R01ES007061 Mol Cell (2013 Mar 07) 23473603
2013
Role of direct reactivity with metals inchemoprotection by N-acetylcysteine againstchromium(VI), c ...
Luczak, Michal W;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Free Radic Biol Med (2013Dec)
23792775
2013
Role of replication protein A in double hollidayjunction dissolution mediated by the BLM-Topo IIIýý...
Xue, Xiaoyu; Raynard,Steven; Busygina,Valeria; Singh,Akhilesh K; Sung,Patrick
R01ES007061 J Biol Chem (2013 May17)
23543748
2013
Roles of DNA helicases in the mediation andregulation of homologous recombination.
Daley, James M; Niu,Hengyao; Sung, Patrick
R01ES007061 Adv Exp Med Biol (2013) 23161012
2013
Structure and function of the DNA ligases encoded bythe mammalian LIG3 gene.
Tomkinson, Alan E;Sallmyr, Annahita
R01ES012512 Gene (2013 Dec 01) 24013086
2013
Targeting abnormal DNA double-strand break repair intyrosine kinase inhibitor-resistant chronic mye ...
Tobin, L A; Robert, C;Rapoport, A P; Gojo, I;Baer, M R; Tomkinson,A E; Rassool, F V
R01ES012512 Oncogene (2013 Apr 04) 22641215
2013
Thymoquinone inhibits autophagy and inducescathepsin-mediated, caspase-independent cell death ingl ...
Racoma, Ira O; Meisen,Walter Hans; Wang,Qi-En; Kaur, Balveen;Wani, Altaf A
R01ES012991 PLoS One (2013) 24039814
2013
Uptake, p53 pathway activation, and cytotoxicresponses for Co(II) and Ni(II) in human lung cells: i...
Green, Samantha E;Luczak, Michal W;Morse, Jessica L;DeLoughery, Zachary;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Toxicol Sci (2013 Dec) 24068677
2013
A DNA hypermethylation module for thestem/progenitor cell signature of cancer.
Easwaran, Hariharan;Johnstone, Sarah E;Van Neste, Leander;Ohm, Joyce;Mosbruger, Tim; Wang,...
R01ES011858 Genome Res (2012 May) 22391556
2012
A two-dimensional ERK-AKT signaling code for anNGF-triggered cell-fate decision.
Chen, Jia-Yun; Lin,Jia-Ren; Cimprich,Karlene A; Meyer,Tobias
R01ES016486 Mol Cell (2012 Jan 27) 22206868
2012
Characterization of human DNA polymerase delta andits subassemblies reconstituted by expression in ...
Zhou, Yajing; Meng,Xiao; Zhang, Sufang;Lee, Ernest Y C; Lee,Marietta Y W T
R56ES014737 PLoS One (2012) 22723953
2012
DNMT1 modulates gene expression without itscatalytic activity partially through its interactions wi ...
Clements, Eriko G;Mohammad, Helai P;Leadem, Benjamin R;Easwaran, Hariharan;Cai, Yi; Van Nes ...
R01ES011858 Nucleic Acids Res (2012May)
22278882
2012
Environmentally induced epigenetic transgenerationalinheritance of phenotype and disease.
Guerrero-Bosagna,Carlos; Skinner,Michael K
R01ES012974,R01ES012974
Mol Cell Endocrinol (2012May 06)
22020198
2012
Epigenetic transgenerational inheritance of alteredstress responses.
Crews, David; Gillette,Ross; Scarpino, SamuelV; Manikkam, Mohan;Savenkova, Marina I;Skinner ...
R01ES012974,R01ES012974
Proc Natl Acad Sci U S A(2012 Jun 5)
22615374
2012
Epigenetic transgenerational inheritance of somatictranscriptomes and epigenetic control regions.
Skinner, Michael K;Manikkam, Mohan;Haque, Md M; Zhang,Bin; Savenkova, MarinaI
R01ES012974,R01ES012974
Genome Biol (2012 Oct03)
23034163
2012
Epigenetic transgenerational inheritance of vinclozolininduced mouse adult onset disease and associ ...
Guerrero-Bosagna,Carlos; Covert, TrevorR; Haque, Md M;Settles, Matthew;Nilsson, Eric E; Anw ...
R01ES012974,R01ES012974
Reprod Toxicol (2012Dec)
23041264
2012
Extrachromosomal microDNAs and chromosomalmicrodeletions in normal tissues.
Shibata, Yoshiyuki;Kumar, Pankaj; Layer,Ryan; Willcox,Smaranda; Gagan,Jeffrey R; Griffith, ...
R56ES013773 Science (2012 Apr 06) 22403181
2012
Finally, polyubiquitinated PCNA gets recognized. Zeman, Michelle K;Cimprich, Karlene A
R01ES016486 Mol Cell (2012 Aug 10) 22883622
2012
Increased risk of lung cancer associated with afunctionally impaired polymorphic variant of the hum...
Dey, Sanjib; Maiti,Amit K; Hegde,Muralidhar L; Hegde,Pavana M; Boldogh,Istvan; Sarkar, Par ...
R01ES012512 DNA Repair (Amst) (2012Jun 01)
22497777
2012
Lack of CAK complex accumulation at DNA damagesites in XP-B and XP-B/CS fibroblasts reveals differe...
Zhu, Qianzheng; Wani,Gulzar; Sharma, Nidhi;Wani, Altaf
R01ES012991 DNA Repair (Amst) (2012Dec 1)
23083890
2012
Mechanistic insights into RAD51-associated protein 1(RAD51AP1) action in homologous DNA repair.
Dunlop, Myun Hwa;Dray, Eloïse; Zhao,Weixing; San Filippo,Joseph; Tsai,Miaw-Sheue; Leung, S...
R01ES007061 J Biol Chem (2012 Apr 06) 22375013
2012
Metabolism of Cr(VI) by ascorbate but not glutathioneis a low oxidant-generating process.
Wong, Victor;Armknecht, Susan;Zhitkovich, Anatoly
P42ES013660,R01ES008786
J Trace Elem Med Biol(2012 Jun)
22572042
2012
Novel attributes of Hed1 affect dynamics and activityof the Rad51 presynaptic filament during meiot ...
Busygina, Valeria;Saro, Dorina; Williams,Gareth; Leung,Wing-Kit; Say, AmandaF; Sehorn, Mic ...
R01ES007061 J Biol Chem (2012 Jan 06) 22115747
2012
Nucleotide excision repair factor XPC enhances DNAdamage-induced apoptosis by downregulating the an ...
Wang, Qi-En; Han,Chunhua; Zhang, Bo;Sabapathy, Kanaga;Wani, Altaf A
R01ES012991 Cancer Res (2012 Feb 01) 22174370
2012
Perinatal exposure to 50 ppb sodium arsenate induceshypothalamic-pituitary-adrenal axis dysregulati ...
Goggin, Samantha L;Labrecque, Matthew T;Allan, Andrea M
R01ES019583 Neurotoxicology (2012Oct)
22960421
2012
Pesticide and insect repellent mixture (permethrin andDEET) induces epigenetic transgenerational in ...
Manikkam, Mohan;Tracey, Rebecca;Guerrero-Bosagna,Carlos; Skinner,Michael K
R01ES012974,R01ES012974
Reprod Toxicol (2012Dec)
22975477
2012
RAD51 protein ATP cap regulates nucleoproteinfilament stability.
Amunugama, Ravindra;He, Yujiong; Willcox,Smaranda; Forties,Robert A; Shim,Kang-Sup; Bundsch ...
R56ES013773 J Biol Chem (2012 Mar16)
22275364
2012
Role of DNA polymerases in repeat-mediated genomeinstability.
Shah, Kartik A;Shishkin, Alexander A;Voineagu, Irina;Pavlov, Youri I;Shcherbakova, Polina V...
R01ES015869 Cell Rep (2012 Nov 29) 23142667
2012
S-phase sensing of DNA-protein crosslinks triggersTopBP1-independent ATR activation and p53-mediate...
Wong, VictorChun-Lam; Cash,Haley L; Morse, JessicaL; Lu, Shan;Zhitkovich, Anatoly
R01ES008786 Cell Cycle (2012 Jul 01) 22722496
2012
Spatiotemporal recruitment of human DNApolymerase delta to sites of UV damage.
Chea, Jennifer; Zhang,Sufang; Zhao, Hong;Zhang, Zhongtao; Lee,Ernest Y C;Darzynkiewicz, Zb ...
R56ES014737 Cell Cycle (2012 Aug 01) 22801543
2012
Structure of monoubiquitinated PCNA: implicationsfor DNA polymerase switching and Okazaki fragment...
Zhang, Zhongtao;Zhang, Sufang; Lin, SzuHua Sharon; Wang,Xiaoxiao; Wu, Licheng;Lee, Ernest ...
R56ES014737 Cell Cycle (2012 Jun 01) 22592530
2012
Targeting abnormal DNA repair in therapy-resistantbreast cancers.
Tobin, Lisa A; Robert,Carine; Nagaria, Pratik;Chumsri, Saranya;Twaddell, William;Ioffe, Ol ...
R01ES012512 Mol Cancer Res (2012 Jan) 22112941
2012
The cancer epigenome: its origins, contributions totumorigenesis, and translational implications.
Baylin, Stephen B R01ES011858 Proc Am Thorac Soc(2012 May)
22550245
2012
The E288K colon tumor variant of DNA polymeraseýý is a sequence specific mutator.
Murphy, Drew L;Donigan, Katherine A;Jaeger, Joachim;Sweasy, Joann B
R01ES019179 Biochemistry (2012 Jul 3) 22650412
2012
The interaction between polynucleotide kinasephosphatase and the DNA repair protein XRCC1 iscritic ...
Della-Maria, Julie;Hegde, Muralidhar L;McNeill, Daniel R;Matsumoto, Yoshihiro;Tsai, Miaw-Sh ...
R01ES012512 J Biol Chem (2012 Nov09)
22992732
2012
The nucleotide sequence, DNA damage location, andprotein stoichiometry influence the base excision ...
Goula, Agathi-Vasiliki;Pearson, Christopher E;Della Maria, Julie;Trottier, Yvon;Tomkinson, ...
R01ES012512 Biochemistry (2012 May8)
22497302
2012
Transgenerational actions of environmentalcompounds on reproductive disease and identificationof e ...
Manikkam, Mohan;Guerrero-Bosagna,Carlos; Tracey,Rebecca; Haque, MdM; Skinner, Michael K
R01ES012974,R01ES012974
PLoS One (2012) 22389676
2012
Undetectable role of oxidative DNA damage in cellcycle, cytotoxic and clastogenic effects of Cr(VI) ...
Reynolds, Mindy;Armknecht, Susan;Johnston, Tatiana;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Mutagenesis (2012 Jul) 22241526
2012
Y265C DNA polymerase beta knockin mice survivepast birth and accumulate base excision repair interm...
Senejani, Alireza G;Dalal, Shibani; Liu,Yanfeng; Nottoli,Timothy P; McGrath,James M; Clairm ...
R01ES019179 Proc Natl Acad Sci U S A(2012 Apr 24)
22493258
2012
Activation of protein kinase Tel1 through recognitionof protein-bound DNA ends.
Fukunaga, Kenzo;Kwon, Youngho; Sung,Patrick; Sugimoto,Katsunori
R01ES007061 Mol Cell Biol (2011 May) 21402778
2011
Analyses of the yeast Rad51 recombinase A265Vmutant reveal different in vivo roles of Swi2-like fac ...
Chi, Peter; Kwon,YoungHo; Visnapuu,Mari-Liis; Lam, Isabel;Santa Maria, Sergio R;Zheng, Xiu ...
R01ES007061 Nucleic Acids Res (2011Aug)
21558173
2011
ASF1A and ATM regulate H3K56-mediated cell-cyclecheckpoint recovery in response to UV irradiation.
Battu, Aruna; Ray, Alo;Wani, Altaf A
R01ES012991 Nucleic Acids Res (2011Oct)
21727091
2011
Cell cycle regulation of DNA double-strand break endresection by Cdk1-dependent Dna2 phosphorylatio ...
Chen, Xuefeng; Niu,Hengyao; Chung,Woo-Hyun; Zhu, Zhu;Papusha, Alma; Shim,Eun Yong; Lee, S ...
R01ES007061 Nat Struct Mol Biol (2011Sep)
21841787
2011
Child health, developmental plasticity, and epigeneticprogramming.
Hochberg, Z; Feil, R;Constancia, M; Fraga,M; Junien, C; Carel,J-C; Boileau, P; LeBouc, Y ...
R01ES012974,R01ES012974
Endocr Rev (2011 Apr) 20971919
2011
Chromium in drinking water: sources, metabolism, andcancer risks.
Zhitkovich, Anatoly P42ES013660,R01ES008786
Chem Res Toxicol (2011Oct 17)
21766833
2011
Differential contributory roles of nucleotide excisionand homologous recombination repair for enhan ...
Wang, Qi-En; Milum,Keisha; Han, Chunhua;Huang, Yi-Wen; Wani,Gulzar; Thomale,Jurgen; Wani, ...
R01ES012991 Mol Cancer (2011) 21385444
2011
Environmental epigenetic transgenerational inheritanceand somatic epigenetic mitotic stability.
Skinner, Michael K R01ES012974,R01ES012974
Epigenetics (2011 Jul) 21637037
2011
Epigenetic transgenerational actions of endocrinedisruptors.
Skinner, Michael K;Manikkam, Mohan;Guerrero-Bosagna,Carlos
R01ES012974,R01ES012974
Reprod Toxicol (2011 Apr) 21055462
2011
Genomic and epigenomic integration identifies aprognostic signature in colon cancer.
Yi, Joo Mi; Dhir,Mashaal; Van Neste,Leander; Downing,Stephanie R; Jeschke,Jana; Glöckner, ...
R01ES011858 Clin Cancer Res (2011Mar 15)
21278247
2011
Human Mre11/human Rad50/Nbs1 and DNA ligaseIIIalpha/XRCC1 protein complexes act together in analte ...
Della-Maria, Julie;Zhou, Yi; Tsai,Miaw-Sheue; Kuhnlein,Jeff; Carney, James P;Paull, Tanya ...
R01ES012512 J Biol Chem (2011 Sep 30) 21816818
2011
Hypoxia-induced epigenetic regulation and silencingof the BRCA1 promoter.
Lu, Yuhong; Chu,Adrian; Turker,Mitchell S; Glazer,Peter M
R01ES005775 Mol Cell Biol (2011 Aug) 21670155
2011
Inhibition of hypoxia-induced miR-155 radiosensitizeshypoxic lung cancer cells.
Babar, Imran A;Czochor, Jennifer;Steinmetz, Allison;Weidhaas, Joanne B;Glazer, Peter M; Sla ...
R01ES005775 Cancer Biol Ther (2011Nov 15)
22027557
2011
Loss of a single Hic1 allele accelerates polypformation in Apc(Δ716) mice.
Mohammad, H P;Zhang, W; Prevas, H S;Leadem, B R; Zhang,M; Herman, J G;Hooker, C M; Watkin ...
R01ES011858 Oncogene (2011 Jun 9) 21297660
2011
Molecular basis for enhancement of the meiotic DMC1recombinase by RAD51 associated protein 1 (RAD51...
Dray, Eloïse; Dunlop,Myun Hwa; Kauppi,Liisa; San Filippo,Joseph; Wiese, Claudia;Tsai, Miaw ...
R01ES007061 Proc Natl Acad Sci U S A(2011 Mar 01)
21307306
2011
Nucleosome disruption by DNA ligase III-XRCC1promotes efficient base excision repair.
Odell, Ian D; Barbour,Joy-El; Murphy, DrewL; Della-Maria, Julie A;Sweasy, Joann B;Tomkinson ...
R01ES012512 Mol Cell Biol (2011 Nov) 21930793
2011
Oxidative damage targets complexes containing DNAmethyltransferases, SIRT1, and polycomb members to...
O'Hagan, Heather M;Wang, Wei; Sen,Subhojit; DestefanoShields, Christina; Lee,Stella S; Zhan ...
R01ES011858,T32ES007141
Cancer Cell (2011 Nov 15) 22094255
2011
Participation of translesion synthesis DNApolymerases in the maintenance of chromosomeintegrity in ...
Kochenova, O V;Soshkina, J V;Stepchenkova, E I;Inge-Vechtomov, S G;Shcherbakova, P V
R01ES015869 Biochemistry (Mosc)(2011 Jan)
21568839
2011
Processing of DNA structures via DNA unwinding andbranch migration by the S. cerevisiae Mph1 protei ...
Zheng, Xiao-Feng;Prakash, Rohit; Saro,Dorina; Longerich,Simonne; Niu,Hengyao; Sung, Patric...
R01ES007061 DNA Repair (Amst) (2011Oct 10)
21880555
2011
RAD51-associated protein 1 (RAD51AP1) interactswith the meiotic recombinase DMC1 through aconserve ...
Dunlop, Myun Hwa;Dray, Eloïse; Zhao,Weixing; Tsai,Miaw-Sheue; Wiese,Claudia; Schild, David...
R01ES007061 J Biol Chem (2011 Oct 28) 21903585
2011
Reduced expression of MAPK/ERK genes in perinatalarsenic-exposed offspring induced by glucocorticoi ...
Martinez-Finley, EbanyJ; Goggin, Samantha L;Labrecque, Matthew T;Allan, Andrea M
R01ES019583 Neurotoxicol Teratol (2011Sep-Oct)
21784148
2011
Replication protein A safeguards genome integrity bycontrolling NER incision events.
Overmeer, René M;Moser, Jill; Volker,Marcel; Kool, Hanneke;Tomkinson, Alan E;van Zeeland, ...
R01ES012512 J Cell Biol (2011 Feb 07) 21282463
2011
Role of epigenetics in developmental biology andtransgenerational inheritance.
Skinner, Michael K R01ES012974,R01ES012974
Birth Defects Res CEmbryo Today (2011 Mar)
21425441
2011
SHPRH and HLTF act in a damage-specific manner tocoordinate different forms of postreplication repa ...
Lin, Jia-Ren; Zeman,Michelle K; Chen,Jia-Yun; Yee,Muh-Ching; Cimprich,Karlene A
R01ES016486 Mol Cell (2011 Apr 22) 21396873
2011
Stem cell protein Piwil2 modulates chromatinmodifications upon cisplatin treatment.
Wang, Qi-En; Han,Chunhua; Milum,Keisha; Wani, Altaf A
R01ES012991 Mutat Res (2011 Mar 15) 21310163
2011
The non-canonical protein binding site at themonomer-monomer interface of yeast proliferating cell...
Sharma, Neeru M;Kochenova, Olga V;Shcherbakova, Polina V
R01ES015869 J Biol Chem (2011 Sep 23) 21799021
2011
The Rad50 coiled-coil domain is indispensable forMre11 complex functions.
Hohl, Marcel; Kwon,Youngho; Galván,Sandra Muñoz; Xue,Xiaoyu; Tous, Cristina;Aguilera, Andr ...
R01ES007061 Nat Struct Mol Biol (2011Sep 04)
21892167
2011
Thymoquinone up-regulates PTEN expression andinduces apoptosis in doxorubicin-resistant humanbreas ...
Arafa, El-Shaimaa A;Zhu, Qianzheng; Shah,Zubair I; Wani, Gulzar;Barakat, Bassant M;Racoma, ...
R01ES012991 Mutat Res (2011 Jan 10) 21040738
2011
A cancer-associated DNA polymerase delta variantmodeled in yeast causes a catastrophic increase in ...
Daee, Danielle L;Mertz, Tony M;Shcherbakova, Polina V
R01ES015869 Proc Natl Acad Sci U S A(2010 Jan 5)
19966286
2010
Aberrant silencing of cancer-related genes by CpGhypermethylation occurs independently of their spa ...
Easwaran, Hariharan P;Van Neste, Leander;Cope, Leslie; Sen,Subhojit; Mohammad,Helai P; Page ...
R01ES011858 Cancer Res (2010 Oct 15) 20736368
2010
Alterations in the developing testis transcriptomefollowing embryonic vinclozolin exposure.
Clement, Tracy M;Savenkova, Marina I;Settles, Matthew;Anway, Matthew D;Skinner, Michael K
R01ES012974,R01ES012974
Reprod Toxicol (2010Nov)
20566332
2010
Basic helix-loop-helix transcription factor gene familyphylogenetics and nomenclature.
Skinner, Michael K;Rawls, Alan;Wilson-Rawls, Jeanne;Roalson, Eric H
R01ES012974,R01ES012974
Differentiation (2010 Jul) 20219281
2010
Checkpoint recovery after DNA damage: a rolling stopfor CDKs.
Duursma, Anja M;Cimprich, Karlene A
R01ES016486 EMBO Rep (2010 Jun) 20467435
2010
Continued primer synthesis at stalled replication forkscontributes to checkpoint activation.
Van, Christopher; Yan,Shan; Michael, WMatthew; Waga, Shou;Cimprich, Karlene A
R01ES016486 J Cell Biol (2010 Apr 19) 20385778
2010
Crystal structures of RMI1 and RMI2, two OB-foldregulatory subunits of the BLM complex.
Wang, Feng; Yang,Yuting; Singh, ThiyamRamsing; Busygina,Valeria; Guo, Rong;Wan, Ke; Wang, ...
R01ES007061 Structure (2010 Sep 08) 20826342
2010
Dissociation of CAK from core TFIIH reveals afunctional link between XP-G/CS and the TFIIHdisassem ...
Arab, Hany H; Wani,Gulzar; Ray, Alo; Shah,Zubair I; Zhu,Qianzheng; Wani, AltafA
R01ES012991 PLoS One (2010) 20543986
2010
DNA polymerases at the eukaryotic fork-20 years later.
Pavlov, Youri I;Shcherbakova, Polina V
R01ES015869 Mutat Res (2010 Mar 01) 19682465
2010
Enhancement of RAD51 recombinase activity by thetumor suppressor PALB2.
Dray, Eloïse; Etchin,Julia; Wiese, Claudia;Saro, Dorina; Williams,Gareth J; Hammel,Michal; ...
R01ES007061 Nat Struct Mol Biol (2010Oct)
20871616
2010
Epigenetic transgenerational actions of environmentalfactors in disease etiology.
Skinner, Michael K;Manikkam, Mohan;Guerrero-Bosagna,Carlos
R01ES012974,R01ES012974
Trends Endocrinol Metab(2010 Apr)
20074974
2010
Epigenetic transgenerational actions of vinclozolin onpromoter regions of the sperm epigenome.
Guerrero-Bosagna,Carlos; Settles,Matthew; Lucker, Ben;Skinner, Michael K
R01ES012974,R01ES012974
PLoS One (2010) 20927350
2010
Functional capacity of XRCC1 protein variantsidentified in DNA repair-deficient Chinese hamsterova ...
Berquist, Brian R;Singh, DharmendraKumar; Fan, Jinshui;Kim, Daemyung;Gillenwater, Elizabeth...
R01ES012512 Nucleic Acids Res (2010Aug)
20385586
2010
Histone modifications: crucial elements for damageresponse and chromatin restoration.
Zhu, Qianzheng; Wani,Altaf A
R01ES012991 J Cell Physiol (2010 May) 20112283
2010
Hsp27 protects adenocarcinoma cells fromUV-induced apoptosis by Akt and p21-dependentpathways of s ...
Kanagasabai, Ragu;Karthikeyan,Krishnamurthy; Vedam,Kaushik; Qien, Wang;Zhu, Qianzheng; Ilan ...
R01ES012991 Mol Cancer Res (2010Oct)
20858736
2010
Human DNA ligase III recognizes DNA ends bydynamic switching between two DNA-bound states.
Cotner-Gohara,Elizabeth; Kim,In-Kwon; Hammel,Michal; Tainer, John A;Tomkinson, Alan E;Elle ...
R01ES012512 Biochemistry (2010 Jul 27) 20518483
2010
Inhibition of poly(ADP-ribose) polymerasedown-regulates BRCA1 and RAD51 in a pathwaymediated by E2 ...
Hegan, Denise Campisi;Lu, Yuhong; Stachelek,Gregory C; Crosby,Meredith E; Bindra,Ranjit S; ...
R01ES005775 Proc Natl Acad Sci U S A(2010 Feb 02)
20133863
2010
Mapping networks of protein-mediated physicalinteractions between chromatin elements.
Tiwari, Vijay K; Baylin,Stephen B
R01ES011858 Curr Protoc Mol Biol(2010 Jan)
20069537
2010
Mechanism of DNA-protein cross-linking bychromium.
Macfie, Andrea; Hagan,Elizabeth; Zhitkovich,Anatoly
P42ES013660,R01ES008786
Chem Res Toxicol (2010Feb 15)
19877617
2010
Mechanism of the ATP-dependent DNA end-resectionmachinery from Saccharomyces cerevisiae.
Niu, Hengyao; Chung,Woo-Hyun; Zhu, Zhu;Kwon, Youngho; Zhao,Weixing; Chi, Peter;Prakash, R ...
R01ES007061 Nature (2010 Sep 2) 20811460
2010
Metabolic disorders: Fathers' nutritional legacy. Skinner, Michael K R01ES012974,R01ES012974
Nature (2010 Oct 21) 20962833
2010
MHF1-MHF2, a histone-fold-containing proteincomplex, participates in the Fanconi anemia pathwayvia ...
Singh, ThiyamRamsing; Saro, Dorina;Ali, AbdullahMahmood; Zheng,Xiao-Feng; Du,Chang-hu; Kil ...
R01ES007061 Mol Cell (2010 Mar 26) 20347429
2010
Overexpression of DDB2 enhances the sensitivity ofhuman ovarian cancer cells to cisplatin by augmen ...
Barakat, Bassant M;Wang, Qi-En; Han,Chunhua; Milum,Keisha; Yin, De-Tao;Zhao, Qun; Wani, G ...
R01ES012991 Int J Cancer (2010 Aug 15) 20013802
2010
Participation of DNA polymerase zeta in replication ofundamaged DNA in Saccharomyces cerevisiae.
Northam, Matthew R;Robinson, Heather A;Kochenova, Olga V;Shcherbakova, Polina V
R01ES015869 Genetics (2010 Jan) 19841096
2010
Potentiation of temozolomide cytotoxicity byinhibition of DNA polymerase beta is accentuated byBRC ...
Stachelek, Gregory C;Dalal, Shibani;Donigan, Katherine A;Campisi Hegan, Denise;Sweasy, Joan ...
R01ES005775 Cancer Res (2010 Jan 01) 20028873
2010
Promotion and regulation of homologousrecombination by DNA helicases.
Colavito, Sierra;Prakash, Rohit; Sung,Patrick
R01ES007061 Methods (2010 Jul) 20156560
2010
Rad52 SUMOylation affects the efficiency of the DNArepair.
Altmannova, Veronika;Eckert-Boulet, Nadine;Arneric, Milica;Kolesar, Peter;Chaloupkova, Radk ...
R01ES007061 Nucleic Acids Res (2010Aug)
20371517
2010
Role of nuclear architecture in epigenetic alterations incancer.
Easwaran, H P; Baylin,S B
R01ES011858 Cold Spring Harb SympQuant Biol (2010)
21447817
2010
Stress and the epigenetic landscape: a link to thepathobiology of human diseases?
Johnstone, Sarah E;Baylin, Stephen B
R01ES011858 Nat Rev Genet (2010 Nov) 20921961
2010
Targeting abnormal DNA double strand break repair incancer.
Rassool, Feyruz V;Tomkinson, Alan E
R01ES012512 Cell Mol Life Sci (2010Nov)
20697770
2010
XPA impacts formation but not proteasome-sensitiverepair of DNA-protein cross-links induced by chro ...
Zecevic, Alma; Hagan,Elizabeth; Reynolds,Mindy; Poage, Graham;Johnston, Tatiana;Zhitkovich, ...
P42ES013660,R01ES008786
Mutagenesis (2010 Jul) 20410141
2010
XRCC1 deficiency sensitizes human lung epithelialcells to genotoxicity by crocidolite asbestos and ...
Pietruska, Jodie R;Johnston, Tatiana;Zhitkovich, Anatoly;Kane, Agnes B
P42ES013660,R01ES008786
Environ Health Perspect(2010 Dec)
20705543
2010
A deficiency of lunatic fringe is associated with cysticdilation of the rete testis.
Hahn, K L; Beres, B;Rowton, Megan J;Skinner, M K; Chang,Y; Rawls, A;Wilson-Rawls, J
R01ES012974,R01ES012974
Reproduction (2009 Jan) 18801836
2009
A genome-wide siRNA screen reveals diverse cellularprocesses and pathways that mediate genome stabi ...
Paulsen, Renee D; Soni,Deena V; Wollman,Roy; Hahn, Angela T;Yee, Muh-Ching; Guan,Anna; Hes ...
R01ES016486 Mol Cell (2009 Jul 31) 19647519
2009
Assay for human Rad51-mediated DNA displacementloop formation.
Raynard, Steven; Sung,Patrick
R01ES007061 Cold Spring Harb Protoc(2009 Jan)
20147015
2009
Chromatin restoration following nucleotide excisionrepair involves the incorporation of ubiquitinat ...
Zhu, Qianzheng; Wani,Gulzar; Arab, Hany H;El-Mahdy, MohamedA; Ray, Alo; Wani,Altaf A
R01ES012991 DNA Repair (Amst) (2009Feb 01)
19059499
2009
Cooperativity of Mus81.Mms4 with Rad54 in theresolution of recombination and replication intermedia...
Matulova, Petra;Marini, Victoria;Burgess, Rebecca C;Sisakova, Alexandra;Kwon, Youngho; Roth...
R01ES007061 J Biol Chem (2009 Mar20)
19129197
2009
Distinct kinetics of human DNA ligases I, IIIalpha,IIIbeta, and IV reveal direct DNA sensing abilit ...
Chen, Xi; Ballin, Jeff D;Della-Maria, Julie; Tsai,Miaw-Sheue; White,Elizabeth J; Tomkinson,...
R01ES012512 DNA Repair (Amst) (2009Aug 6)
19589734
2009
DNA damage alters DNA polymerase delta to a formthat exhibits increased discrimination against modi ...
Meng, Xiao; Zhou,Yajing; Zhang, Sufang;Lee, Ernest Y C; Frick,David N; Lee, MariettaY W T
R56ES014737 Nucleic Acids Res (2009Feb)
19074196
2009
DNA damage tolerance: when it's OK to makemistakes.
Chang, Debbie J;Cimprich, Karlene A
R01ES016486 Nat Chem Biol (2009 Feb) 19148176
2009
Emerging roles of microRNAs in the molecularresponses to hypoxia.
Crosby, Meredith E;Devlin, Cecilia M;Glazer, Peter M; Calin,George A; Ivan, Mircea
R01ES005775 Curr Pharm Des (2009) 19925433
2009
Environmental signals and transgenerationalepigenetics.
Skinner, Michael K;Guerrero-Bosagna,Carlos
R01ES012974,R01ES012974
Epigenomics (2009 Oct) 20563319
2009
Epigenetic transgenerational effects of endocrinedisruptors on male reproduction.
Guerrero-Bosagna,Carlos M; Skinner,Michael K
R01ES012974,R01ES012974
Semin Reprod Med (2009Sep)
19711250
2009
Functional interactions of meiotic recombinationfactors Rdh54 and Dmc1.
Chi, Peter; Kwon,Youngho; Moses, DanaN; Seong, Changhyun;Sehorn, Michael G;Singh, Akhilesh ...
R01ES007061 DNA Repair (Amst) (2009Feb 1)
19028606
2009
Functional significance of the Rad51-Srs2 complex inRad51 presynaptic filament disruption.
Colavito, Sierra;Macris-Kiss, Margaret;Seong, Changhyun;Gleeson, Olive; Greene,Eric C; Klei ...
R01ES007061 Nucleic Acids Res (2009Nov)
19745052
2009
HARPing on about the DNA damage response duringreplication.
Driscoll, Robert;Cimprich, Karlene A
R01ES016486 Genes Dev (2009 Oct 15) 19833762
2009
Human SNF5/INI1, a component of the humanSWI/SNF chromatin remodeling complex, promotesnucleotide ...
Ray, Alo; Mir, Safita N;Wani, Gulzar; Zhao,Qun; Battu, Aruna; Zhu,Qianzheng; Wang,Qi-En; ...
R01ES012991 Mol Cell Biol (2009 Dec) 19805520
2009
Localization of recombination proteins and Srs2reveals anti-recombinase function in vivo.
Burgess, Rebecca C;Lisby, Michael;Altmannova, Veronika;Krejci, Lumir; Sung,Patrick; Rothste ...
R01ES007061 J Cell Biol (2009 Jun 15) 19506039
2009
MicroRNA regulation of DNA repair gene expressionin hypoxic stress.
Crosby, Meredith E;Kulshreshtha, Ritu;Ivan, Mircea; Glazer,Peter M
R01ES005775 Cancer Res (2009 Feb 01) 19141645
2009
Modulation of nucleotide excision repair bymammalian SWI/SNF chromatin-remodeling complex.
Zhao, Qun; Wang,Qi-En; Ray, Alo; Wani,Gulzar; Han, Chunhua;Milum, Keisha; Wani,Altaf A
R01ES012991 J Biol Chem (2009 Oct 30) 19740755
2009
Progesterone regulation of primordial follicleassembly in bovine fetal ovaries.
Nilsson, Eric E;Skinner, Michael K
R01ES012974,R01ES012974
Mol Cell Endocrinol (2009Dec 10)
19747959
2009
Proliferating cell nuclear antigen uses two distinctmodes to move along DNA.
Kochaniak, Anna B;Habuchi, Satoshi;Loparo, Joseph J;Chang, Debbie J;Cimprich, Karlene A;Wa ...
R01ES016486 J Biol Chem (2009 Jun 26) 19411704
2009
Rapid DNA double-strand breaks resulting fromprocessing of Cr-DNA cross-links by both MutSdimers.
Reynolds, Mindy F;Peterson-Roth,Elizabeth C; Bespalov,Ivan A; Johnston,Tatiana; Gurel, Volk ...
R01ES008786 Cancer Res (2009 Feb 01) 19141647
2009
Regulation of Rad51 recombinase presynapticfilament assembly via interactions with the Rad52mediat ...
Seong, Changhyun;Colavito, Sierra; Kwon,Youngho; Sung,Patrick; Krejci, Lumir
R01ES007061 J Biol Chem (2009 Sep 04) 19605344
2009
Role of the Rad52 amino-terminal DNA bindingactivity in DNA strand capture in homologousrecombinat ...
Shi, Idina; Hallwyl,Swee C L; Seong,Changhyun; Mortensen,Uffe; Rothstein,Rodney; Sung, Pat ...
R01ES007061 J Biol Chem (2009 Nov27)
19812039
2009
Sem1p and Ubp6p orchestrate telomeric silencing bymodulating histone H2B ubiquitination and H3 acet ...
Qin, Song; Wang, Qien;Ray, Alo; Wani, Gulzar;Zhao, Qun; Bhaumik,Sukesh R; Wani, AltafA
R01ES012991 Nucleic Acids Res (2009Apr)
19188254
2009
Structural transitions within human Rad51nucleoprotein filaments.
Robertson, Ragan B;Moses, Dana N; Kwon,YoungHo; Chan,Pamela; Chi, Peter;Klein, Hannah; Sun ...
R01ES007061 Proc Natl Acad Sci U S A(2009 Aug 4)
19622740
2009
Tangeretin sensitizes cisplatin-resistant human ovariancancer cells through downregulation of phosp ...
Arafa, El-Shaimaa A;Zhu, Qianzheng;Barakat, Bassant M;Wani, Gulzar; Zhao,Qun; El-Mahdy, Mo ...
R01ES012991 Cancer Res (2009 Dec 01) 19903849
2009
Visualizing the disassembly of S. cerevisiae Rad51nucleoprotein filaments.
Robertson, Ragan B;Moses, Dana N; Kwon,YoungHo; Chan,Pamela; Zhao, Weixing;Chi, Peter; Kle ...
R01ES007061 J Mol Biol (2009 May 15) 19327367
2009
WRN helicase promotes repair of DNA double-strandbreaks caused by aberrant mismatch repair of chrom ...
Zecevic, Alma; Menard,Haley; Gurel, Volkan;Hagan, Elizabeth;DeCaro, Rosamaria;Zhitkovich, ...
P42ES013660,R01ES008786,T32ES007272
Cell Cycle (2009 Sep 01) 19652551
2009
Yeast Mph1 helicase dissociates Rad51-made D-loops:implications for crossover control in mitotic re ...
Prakash, Rohit; Satory,Dominik; Dray, Eloïse;Papusha, Almas;Scheller, Jürgen;Kramer, Wilfr ...
R01ES007061 Genes Dev (2009 Jan 01) 19136626
2009
A novel 6C assay uncovers Polycomb-mediated higherorder chromatin conformations.
Tiwari, Vijay K; Cope,Leslie; McGarvey,Kelly M; Ohm, JoyceE; Baylin, Stephen B
R01ES011858 Genome Res (2008 Jul) 18502945
2008
A requirement for DICER to maintain full promoterCpG island hypermethylation in human cancer cells.
Ting, Angela H; Suzuki,Hiromu; Cope, Leslie;Schuebel, Kornel E;Lee, Byron H; Toyota,Minoru ...
R01ES011858 Cancer Res (2008 Apr 15) 18413723
2008
Abnormal DNA methylation of CD133 in colorectaland glioblastoma tumors.
Yi, Joo Mi; Tsai,Hsing-Chen; Glöckner,Sabine C; Lin, Steven;Ohm, Joyce E;Easwaran, Hari; J ...
R01ES011858 Cancer Res (2008 Oct 01) 18829568
2008
ATP-dependent chromatin remodeling by theSaccharomyces cerevisiae homologous recombinationfactor R ...
Kwon, YoungHo;Seong, Changhyun;Chi, Peter; Greene, EricC; Klein, Hannah;Sung, Patrick
R01ES007061 J Biol Chem (2008 Apr 18) 18292093
2008
ATR: an essential regulator of genome integrity. Cimprich, Karlene A;Cortez, David
R01ES016486 Nat Rev Mol Cell Biol(2008 Aug)
18594563
2008
Chronic hypoxia decreases synthesis of homologousrecombination proteins to offset chemoresistance a ...
Chan, Norman;Koritzinsky, Marianne;Zhao, Helen; Bindra,Ranjit; Glazer, Peter M;Powell, Sim ...
R01ES005775 Cancer Res (2008 Jan 15) 18199558
2008
Convergence of mutation and epigenetic alterationsidentifies common genes in cancer that predict fo ...
Chan, Timothy A;Glockner, Sabine; Yi,Joo Mi; Chen, Wei; VanNeste, Leander; Cope,Leslie; He ...
R01ES011858 PLoS Med (2008 May 27) 18507500
2008
Defining a chromatin pattern that characterizesDNA-hypermethylated genes in colon cancer cells.
McGarvey, Kelly M;Van Neste, Leander;Cope, Leslie; Ohm,Joyce E; Herman, JamesG; Van Criekin ...
R01ES011858 Cancer Res (2008 Jul 15) 18632628
2008
Epigenetic inactivation of the canonical Wntantagonist SRY-box containing gene 17 in colorectalcan ...
Zhang, Wei; Glöckner,Sabine C; Guo,Mingzhou; Machida,Emi Ota; Wang, DavidH; Easwaran, Hari ...
R01ES011858 Cancer Res (2008 Apr 15) 18413743
2008
Epigenetic programming of the germ line: effects ofendocrine disruptors on the development of trans ...
Anway, Matthew D;Skinner, Michael K
R01ES012974,R01ES012974
Reprod Biomed Online(2008 Jan)
18252044
2008
Eukaryotic DNA ligases: structural and functionalinsights.
Ellenberger, Tom;Tomkinson, Alan E
R01ES012512 Annu Rev Biochem (2008) 18518823
2008
Genetic and epigenetic mechanisms in metalcarcinogenesis and cocarcinogenesis: nickel, arsenic,and ...
Salnikow, Konstantin;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Chem Res Toxicol (2008Jan)
17970581
2008
Identification and validation of human DNA ligaseinhibitors using computer-aided drug design.
Zhong, Shijun; Chen,Xi; Zhu, Xiao;Dziegielewska, Barbara;Bachman, Kurtis E;Ellenberger, To ...
R01ES012512 J Med Chem (2008 Aug14)
18630893
2008
Integration of CREB and bHLH transcriptionalsignaling pathways through direct heterodimerizationof ...
Muir, Tera;Wilson-Rawls, Jeanne;Stevens, Jeffrey D;Rawls, Alan;Schweitzer, Ronen;Kang, Ch ...
R01ES012974,R01ES012974
Mol Reprod Dev (2008Nov)
18361414
2008
Interaction with RPA is necessary for Rad52 repaircenter formation and for its mediator activity.
Plate, Iben; Hallwyl,Swee C L; Shi, Idina;Krejci, Lumir; Muller,Christian; Albertsen,Line; ...
R01ES007061 J Biol Chem (2008 Oct 24) 18703507
2008
Molecular anatomy of the recombination mediatorfunction of Saccharomyces cerevisiae Rad52.
Seong, Changhyun;Sehorn, Michael G;Plate, Iben; Shi, Idina;Song, Binwei; Chi,Peter; Morten ...
R01ES007061 J Biol Chem (2008 May 2) 18310075
2008
Naringenin protects HaCaT human keratinocytesagainst UVB-induced apoptosis and enhances theremoval ...
El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-En; Wani,Gulzar; Patnaik,Srinivas; Zhao, Qun; ...
R01ES012991 Photochem Photobiol(2008 Mar-Apr)
18086244
2008
PcG proteins, DNA methylation, and gene repressionby chromatin looping.
Tiwari, Vijay K;McGarvey, Kelly M;Licchesi, Julien D F;Ohm, Joyce E; Herman,James G; Schübe ...
R01ES011858 PLoS Biol (2008 Dec 02) 19053175
2008
PCNA is ubiquitinated by RNF8. Zhang, Sufang; Chea,Jennifer; Meng, Xiao;Zhou, Yajing; Lee,Ernest Y C; Lee,Marietta Y W T
R56ES014737 Cell Cycle (2008 Nov 01) 18948756
2008
Phylogenetic and expression analysis of the basichelix-loop-helix transcription factor gene family: ...
Stevens, Jeffrey D;Roalson, Eric H;Skinner, Michael K
R01ES012974,R01ES012974
Differentiation (2008 Nov) 18557763
2008
Rad52 multimerization is important for its nuclearlocalization in Saccharomyces cerevisiae.
Plate, Iben; Albertsen,Line; Lisby, Michael;Hallwyl, Swee C L;Feng, Qi; Seong,Changhyun; R ...
R01ES007061 DNA Repair (Amst) (2008Jan 1)
17888746
2008
Rational design of human DNA ligase inhibitors thattarget cellular DNA replication and repair.
Chen, Xi; Zhong,Shijun; Zhu, Xiao;Dziegielewska, Barbara;Ellenberger, Tom;Wilson, Gerald M ...
R01ES012512 Cancer Res (2008 May 1) 18451142
2008
Reduction with glutathione is a weakly mutagenicpathway in chromium(VI) metabolism.
Guttmann, David;Poage, Graham;Johnston, Tatiana;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Chem Res Toxicol (2008Nov)
18808157
2008
Remodeling of the human papillomavirus type 11replication origin into discrete nucleoprotein partic ...
Sim, Jeonggu; Ozgur,Sezgin; Lin, BiingYuan; Yu, Jei-Hwa;Broker, Thomas R;Chow, Louise T; G ...
R56ES013773 J Mol Biol (2008 Jan 25) 18067922
2008
The chromate-inducible chrBACF operon from thetransposable element TnOtChr confers resistance to ch...
Branco, Rita; Chung,Ana Paula; Johnston,Tatiana; Gurel, Volkan;Morais, Paula;Zhitkovich, A ...
P42ES013660,R01ES008786
J Bacteriol (2008 Nov) 18776016
2008
The p38 mitogen-activated protein kinase augmentsnucleotide excision repair by mediating DDB2 degra ...
Zhao, Qun; Barakat,Bassant M; Qin, Song;Ray, Alo; El-Mahdy,Mohamed A; Wani,Gulzar; Arafa, ...
R01ES012991 J Biol Chem (2008 Nov21)
18806262
2008
Transforming growth factor beta (TGFbeta1,TGFbeta2 and TGFbeta3) null-mutant phenotypes inembryoni ...
Memon, Mushtaq A;Anway, Matthew D;Covert, Trevor R;Uzumcu, Mehmet;Skinner, Michael K
R01ES012974,R01ES012974
Mol Cell Endocrinol (2008Nov 6)
18790002
2008
Transgenerational epigenetic programming of theembryonic testis transcriptome.
Anway, Matthew D;Rekow, Stephen S;Skinner, Michael K
R01ES012974,R01ES012974
Genomics (2008 Jan) 18042343
2008
Two DNA-binding and nick recognition modules inhuman DNA ligase III.
Cotner-Gohara,Elizabeth; Kim,In-Kwon; Tomkinson,Alan E; Ellenberger,Tom
R01ES012512 J Biol Chem (2008 Apr 18) 18238776
2008
Up-regulation of WRN and DNA ligase IIIalpha inchronic myeloid leukemia: consequences for the repai...
Sallmyr, Annahita;Tomkinson, Alan E;Rassool, Feyruz V
R01ES012512 Blood (2008 Aug 15) 18524993
2008
What is an epigenetic transgenerational phenotype? F3or F2.
Skinner, Michael K R01ES012974,R01ES012974
Reprod Toxicol (2008 Jan) 17949945
2008
Analyzing the ATR-mediated checkpoint usingXenopus egg extracts.
Lupardus, Patrick J;Van, Christopher;Cimprich, Karlene A
R01ES016486 Methods (2007 Feb) 17189864
2007
Ascorbate acts as a highly potent inducer of chromatemutagenesis and clastogenesis: linkage to DNA ...
Reynolds, Mindy;Stoddard, Lauren;Bespalov, Ivan;Zhitkovich, Anatoly
R01ES008786,T32ES007272
Nucleic Acids Res (2007) 17169990
2007
Bipartite stimulatory action of the Hop2-Mnd1complex on the Rad51 recombinase.
Chi, Peter; San Filippo,Joseph; Sehorn,Michael G; Petukhova,Galina V; Sung, Patrick
R01ES007061 Genes Dev (2007 Jul 15) 17639080
2007
Cellular vitamin C increases chromate toxicity via adeath program requiring mismatch repair but not ...
Reynolds, Mindy;Zhitkovich, Anatoly
R01ES008786 Carcinogenesis (2007 Jul) 17301063
2007
Co-repression of mismatch repair gene expression byhypoxia in cancer cells: role of the Myc/Max net ...
Bindra, Ranjit S;Glazer, Peter M
R01ES005775 Cancer Lett (2007 Jul 8) 17275176
2007
Comparing the DNA hypermethylome with genemutations in human colorectal cancer.
Schuebel, Kornel E;Chen, Wei; Cope,Leslie; Glöckner,Sabine C; Suzuki,Hiromu; Yi, Joo-Mi; C...
R01ES011858 PLoS Genet (2007 Sep) 17892325
2007
DNA methylation and complete transcriptionalsilencing of cancer genes persist after depletion of EZ...
McGarvey, Kelly M;Greene, Eriko; Fahrner,Jill A; Jenuwein,Thomas; Baylin,Stephen B
R01ES011858 Cancer Res (2007 Jun 1) 17545586
2007
Epigenetic transgenerational actions of vinclozolin onthe development of disease and cancer.
Skinner, Michael K;Anway, Matthew D
R01ES012974,R01ES012974
Crit Rev Oncog (2007Aug)
17956218
2007
hTERT is expressed in cancer cell lines despitepromoter DNA methylation by preservation ofunmethyl ...
Zinn, Rebekah L; Pruitt,Kevin; Eguchi, Sayaka;Baylin, Stephen B;Herman, James G
R01ES011858 Cancer Res (2007 Jan 1) 17210699
2007
Inhibition of lysine-specific demethylase 1 bypolyamine analogues results in reexpression of aberra...
Huang, Yi; Greene,Eriko; Murray Stewart,Tracy; Goodwin,Andrew C; Baylin,Stephen B; Woster, ...
R01ES011858 Proc Natl Acad Sci U S A(2007 May 8)
17463086
2007
Lessons from 50 years of SOS DNA-damage-inducedmutagenesis.
Schlacher, Katharina;Goodman, Myron F
R01ES029680 Nat Rev Mol Cell Biol(2007 07)
17551516
2007
Probing ATR activation with model DNA templates. Cimprich, Karlene A R01ES016486 Cell Cycle (2007 Oct 01) 17700074
2007 Repression of RAD51 gene expression by E2F4/p130complexes in hypoxia.
Bindra, R S; Glazer, PM
R01ES005775 Oncogene (2007 Mar 29) 17001309
2007
Role of Claspin in regulation of nucleotide excisionrepair factor DDB2.
Praetorius-Ibba, Mette;Wang, Qi-En; Wani,Gulzar; El-Mahdy,Mohamed A; Zhu,Qianzheng; Qin, S ...
R01ES012991 DNA Repair (Amst) (2007May 01)
17196446
2007
Role of Dnl4-Lif1 in nonhomologous end-joiningrepair complex assembly and suppression ofhomologous ...
Zhang, Yu; Hefferin,Melissa L; Chen, Ling;Shim, Eun Yong;Tseng, Hui-Min; Kwon,Youngho; Sun ...
R01ES007061 Nat Struct Mol Biol (2007Jul)
17589524
2007
The ATR pathway: fine-tuning the fork. Paulsen, Renee D;Cimprich, Karlene A
R01ES016486 DNA Repair (Amst) (2007Jul 01)
17531546
2007
The epigenomics of cancer. Jones, Peter A; Baylin,Stephen B
R01ES011858 Cell (2007 Feb 23) 17320506
2007
The structural determinants of checkpoint activation. MacDougall, ChristinaA; Byun, Tony S; Van,Christopher; Yee,Muh-ching; Cimprich,Karlene A
R01ES016486 Genes Dev (2007 Apr 15) 17437996
2007
The ubiquitin-proteasome system regulatesp53-mediated transcription at p21waf1 promoter.
Zhu, Q; Wani, G; Yao,J; Patnaik, S; Wang,Q-E; El-Mahdy, M A;Praetorius-Ibba, M;Wani, A A
R01ES012991 Oncogene (2007 Jun 21) 17224908
2007
Transgenerational epigenetic imprints on matepreference.
Crews, David; Gore,Andrea C; Hsu,Timothy S; Dangleben,Nygerma L; Spinetta,Michael; Schaller ...
R01ES012974,R01ES012974
Proc Natl Acad Sci U S A(2007 Apr 3)
17389367
2007
Ubiquitylation-independent degradation of Xerodermapigmentosum group C protein is required for effi ...
Wang, Qi-En;Praetorius-Ibba, Mette;Zhu, Qianzheng;El-Mahdy, MohamedA; Wani, Gulzar; Zhao,...
R01ES012991 Nucleic Acids Res (2007) 17693435
2007
Ascorbate depletion mediates up-regulation ofhypoxia-associated proteins by cell density and nickel...
Karaczyn, Aldona;Ivanov, Sergey;Reynolds, Mindy;Zhitkovich, Anatoly;Kasprzak, Kazimierz S;...
R01ES008786 J Cell Biochem (2006 Apr1)
16288478
2006
ATM mediates oxidative stress-induceddephosphorylation of DNA ligase IIIalpha.
Dong, Zhiwan;Tomkinson, Alan E
R01ES012512 Nucleic Acids Res (2006) 17040896
2006
Basal repression of BRCA1 by multiple E2Fs andpocket proteins at adjacent E2F sites.
Bindra, Ranjit S;Glazer, Peter M
R01ES005775 Cancer Biol Ther (2006Oct)
17106239
2006
Causes of DNA single-strand breaks during reductionof chromate by glutathione in vitro and in cells ...
Messer, Joseph;Reynolds, Mindy;Stoddard, Lauren;Zhitkovich, Anatoly
R01ES008786,T32ES007272
Free Radic Biol Med (2006Jun 1)
16716899
2006
CHK2-dependent phosphorylation of BRCA1 inhypoxia.
Gibson, Shannon L;Bindra, Ranjit S;Glazer, Peter M
R01ES005775 Radiat Res (2006 Oct) 17007555
2006
Cullin 4A-mediated proteolysis of DDB2 protein atDNA damage sites regulates in vivo lesion recognit ...
El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-en; Wani,Gulzar; Praetorius-Ibba,Mette; Wani, ...
R01ES012991 J Biol Chem (2006 May12)
16527807
2006
De novo CpG island methylation in human cancercells.
Jair, Kam-Wing;Bachman, Kurtis E;Suzuki, Hiromu; Ting,Angela H; Rhee, Ina;Yen, Ray-Whay Ch ...
R01ES011858 Cancer Res (2006 Jan 15) 16423997
2006
Differential requirement for DNA methyltransferase 1in maintaining human cancer cell gene promoter ...
Ting, Angela H; Jair,Kam-wing; Schuebel,Kornel E; Baylin,Stephen B
R01ES011858 Cancer Res (2006 Jan 15) 16424002
2006
Differing patterns of genetic instability in micedeficient in the mismatch repair genes Pms2, Mlh1, ...
Hegan, Denise Campisi;Narayanan, Latha; Jirik,Frank R; Edelmann,Winfried; Liskay, RMichael; ...
R01ES005775 Carcinogenesis (2006 Dec) 16728433
2006
DNA damage binding protein component DDB1participates in nucleotide excision repair throughDDB2 DN ...
Li, Jinyou; Wang,Qi-En; Zhu, Qianzheng;El-Mahdy, MohamedA; Wani, Gulzar;Praetorius-Ibba, M ...
R01ES012991 Cancer Res (2006 Sep 01) 16951172
2006
DNA ligases: structure, reaction mechanism, andfunction.
Tomkinson, Alan E;Vijayakumar,Sangeetha; Pascal, JohnM; Ellenberger, Tom
R01ES012512 Chem Rev (2006 Feb) 16464020
2006
Human DNA ligases I, III, and IV-purification andnew specific assays for these enzymes.
Chen, Xi; Pascal, John;Vijayakumar,Sangeetha; Wilson,Gerald M; Ellenberger,Tom; Tomkinson, ...
R01ES012512 Methods Enzymol (2006) 16793394
2006
Lower mutagenicity but higher stability of Cr-DNAadducts formed during gradual chromate activation ...
Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly
P42ES013660,R01ES008786
Carcinogenesis (2006 Nov) 16714765
2006
Monoubiquitination of proliferating cell nuclearantigen induced by stalled replication requires unc ...
Chang, Debbie J;Lupardus, Patrick J;Cimprich, Karlene A
R01ES016486 J Biol Chem (2006 Oct 27) 16959771
2006
NEIL2-initiated, APE-independent repair of oxidizedbases in DNA: Evidence for a repair complex in h ...
Das, Aditi; Wiederhold,Lee; Leppard, John B;Kedar, Padmini; Prasad,Rajendra; Wang,Huxian; ...
R01ES012512 DNA Repair (Amst) (2006Dec 09)
16982218
2006
Overexpression of the DNA mismatch repair factor,PMS2, confers hypermutability and DNA damagetoler ...
Gibson, Shannon L;Narayanan, Latha;Hegan, Denise Campisi;Buermeyer, Andrew B;Liskay, R Mich ...
R01ES005775 Cancer Lett (2006 Dec 8) 16426742
2006
RecA acts in trans to allow replication of damagedDNA by DNA polymerase V.
Schlacher, Katharina;Cox, Michael M;Woodgate, Roger;Goodman, Myron F
R01ES029680 Nature (2006 Aug 24) 16929290
2006
Recombination mediator and Rad51 targeting activitiesof a human BRCA2 polypeptide.
San Filippo, Joseph;Chi, Peter; Sehorn,Michael G; Etchin,Julia; Krejci, Lumir;Sung, Patric ...
R01ES007061 J Biol Chem (2006 Apr 28) 16513631
2006
Roles of ATP binding and ATP hydrolysis in humanRad51 recombinase function.
Chi, Peter; Van Komen,Stephen; Sehorn,Michael G; Sigurdsson,Stefan; Sung, Patrick
R01ES007061 DNA Repair (Amst) (2006Mar 7)
16388992
2006
Silenced tumor suppressor genes reactivated by DNAdemethylation do not return to a fully euchromati ...
McGarvey, Kelly M;Fahrner, Jill A; Greene,Eriko; Martens, Joost;Jenuwein, Thomas;Baylin, S ...
R01ES011858 Cancer Res (2006 Apr 1) 16585178
2006
Yeast recombination factor Rdh54 functionallyinteracts with the Rad51 recombinase and catalyzesRad ...
Chi, Peter; Kwon,Youngho; Seong,Changhyun; Epshtein,Anastasiya; Lam,Isabel; Sung, Patrick; ...
R01ES007061 J Biol Chem (2006 Sep 8) 16831867
2006
Aberrant gene silencing in tumor progression:implications for control of cancer.
Baylin, S B; Chen, W Y R01ES011858 Cold Spring Harb SympQuant Biol (2005)
16869780
2005
Cellular ubiquitination and proteasomal functionspositively modulate mammalian nucleotide excision ...
Wang, Qi-En; Wani,Manzoor A; Chen,Jianming; Zhu,Qianzheng; Wani,Gulzar; El-Mahdy,Mohamed ...
R01ES012991 Mol Carcinog (2005 Jan) 15547920
2005
Deubiquitination by proteasome is coordinated withsubstrate translocation for proteolysis in vivo.
Zhu, Qianzheng; Wani,Gulzar; Wang, Qi-en;El-mahdy, Mohamed;Snapka, Robert M;Wani, Altaf A
R01ES012991 Exp Cell Res (2005 Jul 15) 15950624
2005
DNA repair factor XPC is modified by SUMO-1 andubiquitin following UV irradiation.
Wang, Qi-En; Zhu,Qianzheng; Wani,Gulzar; El-Mahdy,Mohamed A; Li,Jinyou; Wani, Altaf A
R01ES012991 Nucleic Acids Res (2005) 16030353
2005
Effect of amino acid substitutions in the rad50 ATPbinding domain on DNA double strand break repair ...
Chen, Ling; Trujillo,Kelly M; Van Komen,Stephen; Roh, DongHyun; Krejci, Lumir;Lewis, L Kev ...
R01ES007061 J Biol Chem (2005 Jan 28) 15546877
2005
Hypoxia down-regulates DNA double strand breakrepair gene expression in prostate cancer cells.
Meng, Alice X; Jalali,Farid; Cuddihy,Andrew; Chan,Norman; Bindra, RanjitS; Glazer, Peter M ...
R01ES005775 Radiother Oncol (2005Aug)
16026872
2005
Hypoxia-induced down-regulation of BRCA1expression by E2Fs.
Bindra, Ranjit S;Gibson, Shannon L;Meng, Alice;Westermark, Ulrica;Jasin, Maria; Pierce, An...
R01ES005775 Cancer Res (2005 Dec 15) 16357170
2005
Hypoxia-induced phosphorylation of Chk2 in anataxia telangiectasia mutated-dependent manner.
Gibson, Shannon L;Bindra, Ranjit S;Glazer, Peter M
R01ES005775 Cancer Res (2005 Dec 1) 16322218
2005
Importance of chromium-DNA adducts inmutagenicity and toxicity of chromium(VI).
Zhitkovich, Anatoly R01ES008786 Chem Res Toxicol (2005Jan)
15651842
2005
Killing of chromium-damaged cells by mismatchrepair and its relevance to carcinogenesis.
Zhitkovich, Anatoly;Peterson-Roth,Elizabeth; Reynolds,Mindy
R01ES008786 Cell Cycle (2005 Aug) 15970712
2005
Mismatch repair proteins are activators of toxicresponses to chromium-DNA damage.
Peterson-Roth,Elizabeth; Reynolds,Mindy; Quievryn,George; Zhitkovich,Anatoly
R01ES008786,T32ES007272
Mol Cell Biol (2005 May) 15831465
2005
Saccharomyces cerevisiae MPH1 gene, required forhomologous recombination-mediated mutationavoidanc ...
Prakash, Rohit; Krejci,Lumir; Van Komen,Stephen; Anke Schurer,Kirsten; Kramer,Wilfried; Sun ...
R01ES007061 J Biol Chem (2005 Mar 4) 15634678
2005
Thymoquinone induces apoptosis through activation ofcaspase-8 and mitochondrial events in p53-null ...
El-Mahdy, MohamedA; Zhu, Qianzheng;Wang, Qi-En; Wani,Gulzar; Wani, Altaf A
R01ES012991 Int J Cancer (2005 Nov 10) 15906362
2005
Translocation of XRCC1 and DNA ligase IIIalphafrom centrosomes to chromosomes in response toDNA da ...
Okano, Satoshi; Lan, Li;Tomkinson, Alan E;Yasui, Akira
R01ES012512 Nucleic Acids Res (2005) 15653642
2005
Cell-interdependent cisplatin killing byKu/DNA-dependent protein kinase signalingtransduced throug ...
Jensen, Ryan; Glazer,Peter M
R01ES005775 Proc Natl Acad Sci U S A(2004 Apr 20)
15069205
2004
Depletion of intracellular ascorbate by thecarcinogenic metals nickel and cobalt results in the ind...
Salnikow, Konstantin;Donald, Steven P;Bruick, Richard K;Zhitkovich, Anatoly;Phang, James M; ...
R01ES008786 J Biol Chem (2004 Sep 24) 15271983
2004
Differential arrangements of conserved buildingblocks among homologs of the Rad50/Mre11 DNArepair ...
de Jager, Martijn;Trujillo, Kelly M; Sung,Patrick; Hopfner,Karl-Peter; Carney,James P; Tain ...
R01ES007061 J Mol Biol (2004 Jun 11) 15165861
2004
Differentiation of DNA reactive and non-reactivegenotoxic mechanisms using gene expression profile...
Dickinson, Donna A;Warnes, Gregory R;Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly; R...
R01ES008786 Mutat Res (2004 May 18) 15120961
2004
Down-regulation of Rad51 and decreased homologousrecombination in hypoxic cancer cells.
Bindra, Ranjit S;Schaffer, Paul J; Meng,Alice; Woo, Jennifer;Måseide, Kårstein;Roth, Matt ...
R01ES005775 Mol Cell Biol (2004 Oct) 15367671
2004
Human nucleotide excision repair efficiently removeschromium-DNA phosphate adducts and protects cel ...
Reynolds, Mindy;Peterson, Elizabeth;Quievryn, George;Zhitkovich, Anatoly
R01ES008786,T32ES007272
J Biol Chem (2004 Jul 16) 15087443
2004
Meiotic recombination: an affair of two recombinases.
Sehorn, Michael G;Sung, Patrick
R01ES007061 Cell Cycle (2004 Nov) 15547324
2004
Multiple interactions with the Rad51 recombinasegovern the homologous recombination function of Rad...
Raschle, Markus; VanKomen, Stephen; Chi,Peter; Ellenberger,Tom; Sung, Patrick
R01ES007061 J Biol Chem (2004 Dec10)
15465810
2004
Physical and functional interaction between theXPF/ERCC1 endonuclease and hRad52.
Motycka, Teresa A;Bessho, Tadayoshi;Post, Sean M; Sung,Patrick; Tomkinson,Alan E
R01ES007061 J Biol Chem (2004 Apr 2) 14734547
2004
Role of ATP hydrolysis in the antirecombinasefunction of Saccharomyces cerevisiae Srs2 protein.
Krejci, Lumir; Macris,Margaret; Li, Ying; VanKomen, Stephen;Villemain, Jana;Ellenberger, T ...
R01ES007061 J Biol Chem (2004 May28)
15047689
2004
Role of the nuclease activity of Saccharomycescerevisiae Mre11 in repair of DNA double-strandbreak ...
Lewis, L Kevin; Storici,Francesca; Van Komen,Stephen; Calero,Shanna; Sung, Patrick;Resnick, ...
R01ES007061 Genetics (2004 Apr) 15126391
2004
UV radiation-induced XPC translocation withinchromatin is mediated by damaged-DNA bindingprotein, ...
Wang, Qi-En; Zhu,Qianzheng; Wani,Gulzar; Chen, Jianming;Wani, Altaf A
R01ES012991 Carcinogenesis (2004 Jun) 14742321
2004
ATPase and DNA helicase activities of theSaccharomyces cerevisiae anti-recombinase Srs2.
Van Komen, Stephen;Reddy, MotheSreedhar; Krejci,Lumir; Klein, Hannah;Sung, Patrick
R01ES007061 J Biol Chem (2003 Nov 7) 12966095
2003
Decreased expression of the DNA mismatch repairgene Mlh1 under hypoxic stress in mammalian cells.
Mihaylova, Valia T;Bindra, Ranjit S; Yuan,Jianling; Campisi,Denise; Narayanan,Latha; Jensen ...
R01ES005775 Mol Cell Biol (2003 May) 12697826
2003
Elevated levels of DNA-protein crosslinks andmicronuclei in peripheral lymphocytes of tanneryworke ...
Medeiros, M G;Rodrigues, A S;Batoréu, M C; Laires,A; Rueff, J; Zhitkovich,A
R01ES008786 Mutagenesis (2003 Jan) 12473731
2003
GATA-4 and GATA-5 transcription factor genes andpotential downstream antitumor target genes are epi ...
Akiyama, Yoshimitsu;Watkins, Neil; Suzuki,Hiromu; Jair,Kam-Wing; vanEngeland, Manon;Estell ...
R01ES011858 Mol Cell Biol (2003 Dec) 14612389
2003
Gene silencing in cancer in association with promoterhypermethylation.
Herman, James G;Baylin, Stephen B
R01ES011858 N Engl J Med (2003 Nov20)
14627790
2003
Genetic control of interconnected neuronal populationsin the mouse primary visual system.
Seecharan, Dave J;Kulkarni, Anand L; Lu,Lu; Rosen, Glenn D;Williams, Robert W
R01ES012991 J Neurosci (2003 Dec 03) 14657177
2003
Genotoxicity and mutagenicity ofchromium(VI)/ascorbate-generated DNA adducts inhuman and bacterial ...
Quievryn, George;Peterson, Elizabeth;Messer, Joseph;Zhitkovich, Anatoly
R01ES008786,T32ES007272
Biochemistry (2003 Feb 4) 12549927
2003
Rad51 recombinase and recombination mediators. Sung, Patrick; Krejci,Lumir; Van Komen,Stephen; Sehorn,Michael G
R01ES007061 J Biol Chem (2003 Oct 31) 12912992
2003
Yeast xrs2 binds DNA and helps target rad50 andmre11 to DNA ends.
Trujillo, Kelly M; Roh,Dong Hyun; Chen,Ling; Van Komen,Stephen; Tomkinson,Alan; Sung, Patr ...
R01ES007061 J Biol Chem (2003 Dec05)
14522986
2003
Carcinogenic chromium(VI) induces cross-linking ofvitamin C to DNA in vitro and in human lung A549 ...
Quievryn, George;Messer, Joseph;Zhitkovich, Anatoly
R01ES008786 Biochemistry (2002 Mar05)
11863455
2002
Dependence of histone modifications and geneexpression on DNA hypermethylation in cancer.
Fahrner, Jill A; Eguchi,Sayaka; Herman, JamesG; Baylin, Stephen B
R01ES011858 Cancer Res (2002 Dec 15) 12499261
2002
Functional cross-talk among Rad51, Rad54, andreplication protein A in heteroduplex DNA jointformat ...
Van Komen, Stephen;Petukhova, Galina;Sigurdsson, Stefan;Sung, Patrick
R01ES007061 J Biol Chem (2002 Nov15)
12226081
2002
Interaction with Rad51 is indispensable forrecombination mediator function of Rad52.
Krejci, Lumir; Song,Binwei; Bussen,Wendy; Rothstein,Rodney; Mortensen,Uffe H; Sung, Patric ...
R01ES007061 J Biol Chem (2002 Oct 18) 12171935
2002
Reductive activation with cysteine represents achromium(III)-dependent pathway in the induction of...
Zhitkovich, Anatoly;Quievryn, George;Messer, Joseph;Motylevich, Zhanna
R01ES008786 Environ Health Perspect(2002 Oct)
12426121
2002
ATM-dependent expression of the insulin-like growthfactor-I receptor in a pathway regulating radiat ...
Peretz, S; Jensen, R;Baserga, R; Glazer, P M
R01ES005775 Proc Natl Acad Sci U S A(2001 Feb 13)
11172010
2001
Basis for avid homologous DNA strand exchange byhuman Rad51 and RPA.
Sigurdsson, S; Trujillo,K; Song, B; Stratton, S;Sung, P
R01ES007061 J Biol Chem (2001 Mar23)
11124265
2001
DNA pairing and strand exchange by the Escherichiacoli RecA and yeast Rad51 proteins without ATP hy ...
Rice, K P; Eggler, A L;Sung, P; Cox, M M
R01ES007061 J Biol Chem (2001 Oct 19) 11504729
2001
DNA structure-specific nuclease activities in theSaccharomyces cerevisiae Rad50*Mre11 complex.
Trujillo, K M; Sung, P R01ES007061 J Biol Chem (2001 Sep 21) 11454871
2001
Hypermutability to ionizing radiation in mismatchrepair-deficient, Pms2 knockout mice.
Xu, X S; Narayanan, L;Dunklee, B; Liskay, RM; Glazer, P M
R01ES005775 Cancer Res (2001 May 1) 11325851
2001
Mediator function of the human Rad51B-Rad51Ccomplex in Rad51/RPA-catalyzed DNA strandexchange.
Sigurdsson, S; VanKomen, S; Bussen, W;Schild, D; Albala, J S;Sung, P
R01ES007061 Genes Dev (2001 Dec 15) 11751636
2001
Non-oxidative mechanisms are responsible for theinduction of mutagenesis by reduction of Cr(VI) wit ...
Zhitkovich, A; Song, Y;Quievryn, G; Voitkun,V
R01ES008786 Biochemistry (2001 Jan16)
11148050
2001
Promotion of Dnl4-catalyzed DNA end-joining by theRad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes.
Chen, L; Trujillo, K;Ramos, W; Sung, P;Tomkinson, A E
R01ES007061 Mol Cell (2001 Nov) 11741545
2001
Reduction of Cr (VI) by cysteine: significance inhuman lymphocytes and formation of DNA damage inr ...
Quievryn, G; Goulart,M; Messer, J;Zhitkovich, A
R01ES008786 Mol Cell Biochem (2001Jun)
11678591
2001
Structure of the Rad50 x Mre11 DNA repair complexfrom Saccharomyces cerevisiae by electron microsco...
Anderson, D E; Trujillo,K M; Sung, P;Erickson, H P
R01ES007061 J Biol Chem (2001 Oct 5) 11470800
2001
Functional interactions among yeast Rad51recombinase, Rad52 mediator, and replication proteinA in ...
Song, B; Sung, P R01ES007061 J Biol Chem (2000 May26)
10748203
2000
Interactions of the DNA ligase IV-XRCC4 complexwith DNA ends and the DNA-dependent proteinkinase.
Chen, L; Trujillo, K;Sung, P; Tomkinson, AE
R01ES007061 J Biol Chem (2000 Aug25)
10854421
2000
Ionizing radiation-induced apoptosis via separatePms2- and p53-dependent pathways.
Zeng, M; Narayanan, L;Xu, X S; Prolla, T A;Liskay, R M; Glazer, PM
R01ES005775 Cancer Res (2000 Sep 1) 10987303
2000
Loss of DNA-protein crosslinks fromformaldehyde-exposed cells occurs throughspontaneous hydrolysis ...
Quievryn, G;Zhitkovich, A
R01ES008786 Carcinogenesis (2000 Aug) 10910961
2000
Mutagenesis in PMS2- and MSH2-deficient miceindicates differential protection from transversions an...
Andrew, S E; Xu, X S;Baross-Francis, A;Narayanan, L;Milhausen, K; Liskay, RM; Jirik, F R; ...
R01ES005775 Carcinogenesis (2000 Jul) 10874005
2000
Promotion of Rad51-dependent D-loop formation byyeast recombination factor Rdh54/Tid1.
Petukhova, G; Sung, P;Klein, H
R01ES007061 Genes Dev (2000 Sep 01) 10970884
2000
Rats retain chromium in tissues following chronicingestion of drinking water containing hexavalent ...
Sutherland, J E;Zhitkovich, A; Kluz, T;Costa, M
R01ES008786 Biol Trace Elem Res (2000Apr)
11049199
2000
Recombination factors of Saccharomyces cerevisiae. Sung, P; Trujillo, K M;Van Komen, S
R01ES007061 Mutat Res (2000 Jun 30) 10915877
2000
Reductive metabolism of Cr(VI) by cysteine leads tothe formation of binary and ternary Cr--DNA addu ...
Zhitkovich, A; Shrager,S; Messer, J
R01ES008786 Chem Res Toxicol (2000Nov)
11087433
2000
Superhelicity-driven homologous DNA pairing byyeast recombination factors Rad51 and Rad54.
Van Komen, S;Petukhova, G;Sigurdsson, S; Stratton,S; Sung, P
R01ES007061 Mol Cell (2000 Sep) 11030336
2000
Analysis of DNA-protein crosslinking activity ofmalondialdehyde in vitro.
Voitkun, V; Zhitkovich,A
R01ES008786 Mutat Res (1999 Mar 08) 10064853
1999
Different mutator phenotypes in Mlh1- versusPms2-deficient mice.
Yao, X; Buermeyer, AB; Narayanan, L; Tran,D; Baker, S M; Prolla,T A; Glazer, P M;Liskay, ...
R01ES005775 Proc Natl Acad Sci U S A(1999 Jun 08)
10359802
1999
Single strand DNA binding and annealing activities inthe yeast recombination factor Rad59.
Petukhova, G; Stratton,S A; Sung, P
R01ES007061 J Biol Chem (1999 Nov26)
10567339
1999
The Tyr-265-to-Cys mutator mutant of DNApolymerase beta induces a mutator phenotype inmouse LN12 c ...
Clairmont, C A;Narayanan, L; Sun, KW; Glazer, P M;Sweasy, J B
R01ES005775 Proc Natl Acad Sci U S A(1999 Aug 17)
10449735
1999
Yeast Rad54 promotes Rad51-dependent homologousDNA pairing via ATP hydrolysis-driven change inDNA ...
Petukhova, G; VanKomen, S; Vergano, S;Klein, H; Sung, P
R01ES007061 J Biol Chem (1999 Oct 08) 10506208
1999
Cr(III)-mediated crosslinks of glutathione or aminoacids to the DNA phosphate backbone are mutageni ...
Voitkun, V; Zhitkovich,A; Costa, M
R01ES008786 Nucleic Acids Res (1998Apr 15)
9518499 1998
Nuclease activities in a complex of humanrecombination and DNA repair factors Rad50, Mre11,and p95 ...
Trujillo, K M; Yuan, SS; Lee, E Y; Sung, P
R01ES007061 J Biol Chem (1998 Aug21)
9705271 1998
Utilization of DNA-protein cross-links as a biomarkerof chromium exposure.
Zhitkovich, A; Voitkun,V; Kluz, T; Costa, M
R01ES008786 Environ Health Perspect(1998 Aug)
9703480 1998
Elevated levels of mutation in multiple tissues of micedeficient in the DNA mismatch repair gene Pm ...
Narayanan, L; Fritzell, JA; Baker, S M; Liskay,R M; Glazer, P M
R01ES005775 Proc Natl Acad Sci U S A(1997 Apr 01)
9096356 1997
Function of yeast Rad52 protein as a mediator betweenreplication protein A and the Rad51 recombinas ...
Sung, P R01ES007061 J Biol Chem (1997 Nov07)
9353267 1997
Insulin-like growth factor-I receptor overexpressionmediates cellular radioresistance and local bre ...
Turner, B C; Haffty, BG; Narayanan, L; Yuan,J; Havre, P A; Gumbs,A A; Kaplan, L;Burgaud, ...
R01ES005775 Cancer Res (1997 Aug 1) 9242428 1997
Role of DNA mismatch repair in the cytotoxicity ofionizing radiation.
Fritzell, J A; Narayanan,L; Baker, S M; Bronner,C E; Andrew, S E;Prolla, T A; Bradley, A;...
R01ES005775 Cancer Res (1997 Nov 15) 9371516 1997
Yeast Rad55 and Rad57 proteins form a heterodimerthat functions with replication protein A to promo ...
Sung, P R01ES007061 Genes Dev (1997 May 01) 9159392 1997
Dual requirement for the yeast MMS19 gene in DNArepair and RNA polymerase II transcription.
Lauder, S; Bankmann,M; Guzder, S N; Sung,P; Prakash, L; Prakash,S
R01ES007061 Mol Cell Biol (1996 Dec) 8943333 1996
Frequent spontaneous deletions at a shuttle vectorlocus in transgenic mice.
Leach, E G; Gunther, EJ; Yeasky, T M;Gibson, L H;Yang-Feng, T L;Glazer, P M
R01ES005775 Mutagenesis (1996 Jan) 8671715 1996
Genetic instability induced by the tumormicroenvironment.
Reynolds, T Y;Rockwell, S; Glazer, PM
R01ES005775 Cancer Res (1996 Dec 15) 8971187 1996
Mutagenesis by third-strand-directed psoralen adductsin repair-deficient human cells: high frequenc ...
Raha, M; Wang, G;Seidman, M M; Glazer,P M
R01ES005775 Proc Natl Acad Sci U S A(1996 Apr 02)
8610147 1996
Mutagenesis in mammalian cells induced by triplehelix formation and transcription-coupled repair.
Wang, G; Seidman, MM; Glazer, P M
R01ES005775 Science (1996 Feb 09) 8628995 1996
Recombination induced by triple-helix-targeted DNAdamage in mammalian cells.
Faruqi, A F; Seidman,M M; Segal, D J;Carroll, D; Glazer, P M
R01ES005775 Mol Cell Biol (1996 Dec) 8943337 1996
Targeted mutagenesis mediated by the triple helixformation.
Glazer, P M; Wang, G;Havre, P A; Gunther, EJ
R01ES005775 Methods Mol Biol (1996) 8849999 1996
Tissue specificity of spontaneous point mutations inlambda supF transgenic mice.
Leach, E G; Narayanan,L; Havre, P A; Gunther,E J; Yeasky, T M;Glazer, P M
R01ES005775 Environ Mol Mutagen(1996)
8991078 1996
Yeast Rad51 recombinase mediates polar DNA strandexchange in the absence of ATP hydrolysis.
Sung, P; Stratton, S A R01ES007061 J Biol Chem (1996 Nov08)
8910403 1996
Altered repair of targeted psoralen photoadducts in thecontext of an oligonucleotide-mediated tripl ...
Wang, G; Glazer, P M R01ES005775 J Biol Chem (1995 Sep 22) 7673252 1995
DNA strand exchange mediated by a RAD51-ssDNAnucleoprotein filament with polarity opposite to that ...
Sung, P; Robberson, DL
R01ES007061 Cell (1995 Aug 11) 7634335 1995
G:C transversions in X-irradiated mouse cells.">Frequent T:A-->G:C transversions in X-irradiatedmouse cells.
Yuan, J; Yeasky, T M;Rhee, M C; Glazer, P M
R01ES005775 Carcinogenesis (1995 Jan) 7834808 1995
Induction of p53 in mouse cells decreases mutagenesisby UV radiation.
Yuan, J; Yeasky, T M;Havre, P A; Glazer, P M
R01ES005775 Carcinogenesis (1995 Oct) 7586125 1995
Mutagenesis by 8-methoxypsoralen and5-methylangelicin photoadducts in mouse fibroblasts:mutations ...
Gunther, E J; Yeasky, TM; Gasparro, F P;Glazer, P M
R01ES005775 Cancer Res (1995 Mar 15) 7882323 1995
Targeted mutagenesis in mammalian cells mediated byintracellular triple helix formation.
Wang, G; Levy, D D;Seidman, M M; Glazer,P M
R01ES005775 Mol Cell Biol (1995 Mar) 7862165 1995
Site-specific targeting of psoralen photoadducts with atriple helix-forming oligonucleotide: charac ...
Gasparro, F P; Havre, PA; Olack, G A;Gunther, E J; Glazer, PM
R01ES005775 Nucleic Acids Res (1994Jul 25)
8052539 1994
High efficiency, restriction-deficient in vitro packagingextracts for bacteriophage lambda DNA usin ...
Gunther, E J; Murray, NE; Glazer, P M
R01ES005775 Nucleic Acids Res (1993Aug 11)
8396240 1993
Targeted mutagenesis of DNA using triplehelix-forming oligonucleotides linked to psoralen.
Havre, P A; Gunther, EJ; Gasparro, F P; Glazer,P M
R01ES005775 Proc Natl Acad Sci U S A(1993 Aug 15)
8356097 1993
Targeted mutagenesis of simian virus 40 DNAmediated by a triple helix-forming oligonucleotide.
Havre, P A; Glazer, P M R01ES005775 J Virol (1993 Dec) 8230456 1993