PROTEIN SYNTHESIS

Transcription and Translation

Central Dogma

DNA RNA Protein

Transcription

Translation

Transcription and Translation

Transcription

mRNA makes a copy of the DNA strand! Adenine Base Pairs with Uracil Base Pairs with Guanine Base Pairs with Cytosine Base Pairs with

ThymineAdenin

e CytosineGuanine

Step 1- DNA Unzips.

Step 2- mRNA nucleotides match to their complementary

bases.

Step 3- mRNA leaves the nucleus to go to ribosome in the cytoplasm.

Translation At the ribosome, mRNA is “translated” in sets of

three nucleotides called codons.

tRNA matches the correct amino acid to its codon using an anticodon (complementary base pair)The codon CCG has an anticodon The codon AUG has an anticodon

Chains of amino acids are PROTEINS!!!

GGC

UAC

Step 1: The mRNA start codon, AUG, is oriented at the ribosome P site.

Start Codon

Step 2: The tRNA molecule matches the amino acid methionine to the codon using an anticodon- UAC.

U A C

C G G

Anti-Codon

Step 3: The next tRNA molecule carries the next matching amino acid to the A site

where a peptide bond forms between the two amino acids.

Peptide Bond

U A CC G G

A C C

Step 4: The ribosome shifts one codon in the 3’ position so the next tRNA can

match the codon to its amino acid.

U A C

U G A

C G G A C C

TR

AN

SLA

TIO

N

Another way to look at it.

Using your notes and diagram, complete the Venn diagram by placing the

statements in the correct location.

A. Occurs in nucleusB. Occurs on

ribosome C. Assembly of

proteinsD. DNA is copiedE. Involves mRNAF. Involves tRNA

G. Involves DNAH. Amino acids are

matched to their codon.

I. DNA unzipsJ. Peptide bonds are

formed

A B

CD

E FG

HIJ

Transcription Translation

Codon Chart

CodonAUG

Amino AcidMethionine

1st Base

2nd

Base3rd

Base

CODON BINGO!!

Label each space on your Bingo card with one of the following amino acids

You will have to use some amino acids more than once

Arginine Aspartic Acid Serine CysteineLeucine Glutamic Acid Proline HistidineGlycineTryptophan ThreonineGlutamineValine Asparagine Tyrosine IsoleucineAlanineMethionine Lysine Phenylalaine

You can also use the word stop in one of the squares!