+ All Categories

Home > Documents > Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic...

Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic...

Date post:	17-Jul-2020
Category:	Documents
Upload:	others
View:	17 times
Download:	0 times

Download Report this document

Share this document with a friend

Embed Size (px):

17

Transgenic Animals

Transcript

Page 1: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 2: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 3: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 4: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 5: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

“Cloning”

Page 6: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 7: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Tissue specific Expression

CFTR: Cystic Fibrosis Transmembrane Conductance Regulator

Page 8: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Tissue specific Expression

Page 9: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic animals as organ supplier

Immunological Barriers

Hyperacute rejectionAcute vascular rejectionCellular rejectionChronic rejection

Porcine endogenous retroviruses

Humanizing the pig:

Introduction of Human Genes

Knock out of pig genes -1.3 galactosyltransferase avoid immunogenic reaction

Page 10: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 11: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 12: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 13: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 14: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 15: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 16: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Page 17: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Recommended

(Re)producing transgenic pigs for xenotransplantation ... · PDF fileis a successful method for generating novel transgenic pig lines, efficiency in large scale reproduction of already

Comparative proteomics of Bt-transgenic and non-transgenic ...

Success Story of Transgenic crops Transgenic crops.

Harlan Transgenic Services Harlan UK & Harlan BV Transgenic Services platforms.

Problems in Gene Therapy and Transgenesis Bio...Producing transgenic animals Purpose: Production of heterolog proteins in transgenic animals Principle: Integration of heterolog DNA

Application of Transgenic Technologies on Transgenic ...

TRANSGENIC CROPS

Transgenic Tech

TRANSGENIC TECHNOLOGY

Transgenic goats producing an improved version of ... · produce cetuximab in milk. We demonstrated trans-generational stability of the integrated transgenes and cetuximab production

Product Development & Commercialization Kiran K … · National Institute of Nutrition, Hyderabad, Nov. 17-18, ... Producing Transgenic Plants ... Crop biology document,

Transgenic plants

Metabolic and Cardiovascular Disease Models and Services...LIGHT PRODUCING TRANSGENIC ANIMALS ® (LPTA ®) Reporter models expressing luciferase under the control of various promoters,

Transgenic Mice - Massachusetts General · PDF fileEarly transgenic mice . ... rabbit, or pig: a) The availability of genetically homogeneous inbred strains ... transgenic transgenic

The Cost of Research and Development for Producing a ...ris.org.in/images/RIS_images/pdf/article4_v11n1.pdf · Keywords: Biosafety regulations, Cost of biosafety, R&D, Transgenic

MOL.911 Transgenic Plants - ftp.tugraz.atftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · 21 Bacillus thuringiensis Toxin Cry toxins belonging to the three domain

Transgenic Organisms