+ All Categories
Home > Documents > TREATMENT OF BACTERIAL ENDOCARDITIS

TREATMENT OF BACTERIAL ENDOCARDITIS

Date post: 05-Jan-2017
Category:
Upload: dinhmien
View: 217 times
Download: 4 times
Share this document with a friend
2
117 " XBD=207 XHG=133 YBD=212 YHG=180>and " XBD=313 XHG=224 YBD=212 YHG=180>Glen " XBD=341 XHG=328 YBD=199 YHG=180>6 " XBD=464 XHG=355 YBD=212 YHG=180>when " XBD=572 XHG=479 YBD=222 YHG=181>they " XBD=871 XHG=589 YBD=213 YHG=181>demonstrated " XBD=973 XHG=887 YBD=212 YHG=181>that " XBD=1166 XHG=989 YBD=221 YHG=181>ordinary " XBD=1302 XHG=1184 YBD=217 YHG=181>doses, " XBD=226 XHG=135 YBD=258 YHG=225>such " XBD=283 XHG=242 YBD=256 YHG=234>as " XBD=422 XHG=303 YBD=265 YHG=225>might " XBD=489 XHG=442 YBD=256 YHG=225>be " XBD=600 XHG=508 YBD=258 YHG=225>used " XBD=968 XHG=619 YBD=265 YHG=224>prophylactically, " XBD=1065 XHG=988 YBD=256 YHG=225>had " XBD=1134 XHG=1086 YBD=255 YHG=234>an " XBD=1304 XHG=1153 YBD=265 YHG=224>insigni- " XBD=285 XHG=135 YBD=310 YHG=270>ficantly " XBD=452 XHG=299 YBD=300 YHG=269>adverse " XBD=576 XHG=467 YBD=301 YHG=269>effect " XBD=641 XHG=592 YBD=300 YHG=279>on " XBD=980 XHG=654 YBD=309 YHG=269>intelligence-test " XBD=1127 XHG=995 YBD=300 YHG=277>scores. " XBD=1224 XHG=1179 YBD=299 YHG=269>In " XBD=1305 XHG=1238 YBD=299 YHG=268>the " XBD=233 XHG=134 YBD=355 YHG=315>early " XBD=367 XHG=246 YBD=354 YHG=316>stages " XBD=421 XHG=383 YBD=344 YHG=313>of " XBD=501 XHG=434 YBD=344 YHG=313>the " XBD=736 XHG=516 YBD=353 YHG=314>Normandy " XBD=960 XHG=752 YBD=353 YHG=313>campaign, " XBD=1128 XHG=978 YBD=344 YHG=311>Colonel " XBD=1305 XHG=1142 YBD=353 YHG=313>Thomp- " XBD=199 XHG=133 YBD=391 YHG=369>son " XBD=259 XHG=221 YBD=389 YHG=358>of " XBD=344 XHG=279 YBD=389 YHG=359>the " XBD=427 XHG=367 YBD=389 YHG=357>US " XBD=570 XHG=450 YBD=397 YHG=357>Army " XBD=673 XHG=591 YBD=388 YHG=357>told " XBD=885 XHG=699 YBD=396 YHG=358>reporters " XBD=994 XHG=907 YBD=387 YHG=357>that " XBD=1105 XHG=1019 YBD=397 YHG=356>75% " XBD=1167 XHG=1129 YBD=388 YHG=357>of " XBD=1308 XHG=1197 YBD=388 YHG=358>acute " XBD=373 XHG=104 YBD=434 YHG=396>breakdowns " XBD=430 XHG=391 YBD=432 YHG=401>in " XBD=513 XHG=447 YBD=432 YHG=401>the " XBD=632 XHG=529 YBD=432 YHG=401>front " XBD=723 XHG=650 YBD=432 YHG=402>line " XBD=803 XHG=742 YBD=431 YHG=410>are " XBD=933 XHG=822 YBD=441 YHG=400>being " XBD=1016 XHG=950 YBD=440 YHG=401>got " XBD=1131 XHG=1033 YBD=431 YHG=400>back " XBD=1190 XHG=1148 YBD=431 YHG=402>to " XBD=1306 XHG=1210 YBD=440 YHG=400>duty " XBD=184 XHG=136 YBD=487 YHG=448>by " XBD=303 XHG=201 YBD=477 YHG=447>these " XBD=506 XHG=321 YBD=476 YHG=445>methods. " XBD=645 XHG=556 YBD=475 YHG=444>This " XBD=778 XHG=662 YBD=484 YHG=444>figure " XBD=983 XHG=796 YBD=475 YHG=445>contrasts " XBD=1092 XHG=999 YBD=475 YHG=443>with " XBD=1175 XHG=1110 YBD=474 YHG=444>the " XBD=1306 XHG=1194 YBD=474 YHG=444>much " XBD=241 XHG=136 YBD=521 YHG=491>lower " XBD=333 XHG=265 YBD=520 YHG=499>one " XBD=396 XHG=357 YBD=519 YHG=489>of " XBD=484 XHG=418 YBD=519 YHG=489>the " XBD=683 XHG=507 YBD=519 YHG=488>numbers " XBD=886 XHG=707 YBD=519 YHG=488>returned " XBD=949 XHG=907 YBD=518 YHG=489>to " XBD=1071 XHG=974 YBD=527 YHG=486>duty " XBD=1192 XHG=1093 YBD=518 YHG=487>from " XBD=1306 XHG=1214 YBD=519 YHG=487>base " XBD=323 XHG=133 YBD=573 YHG=533>hospitals, " XBD=420 XHG=345 YBD=563 YHG=532>and " XBD=648 XHG=439 YBD=572 YHG=534>represents " XBD=690 XHG=669 YBD=562 YHG=541>a " XBD=922 XHG=712 YBD=572 YHG=531>significant " XBD=1112 XHG=943 YBD=562 YHG=531>advance " XBD=1171 XHG=1132 YBD=562 YHG=531>in " XBD=1306 XHG=1191 YBD=562 YHG=532>treat- " XBD=247 XHG=136 YBD=609 YHG=578>ment. " XBD=414 XHG=297 YBD=607 YHG=576>These " XBD=565 XHG=425 YBD=607 YHG=576>lessons " XBD=698 XHG=579 YBD=616 YHG=575>might " XBD=758 XHG=711 YBD=606 YHG=576>be " XBD=922 XHG=771 YBD=615 YHG=575>applied " XBD=1068 XHG=934 YBD=615 YHG=575>during " XBD=1144 XHG=1079 YBD=606 YHG=575>the " XBD=1307 XHG=1155 YBD=615 YHG=575>present " XBD=347 XHG=137 YBD=661 YHG=622>long-range " XBD=499 XHG=367 YBD=651 YHG=619>attack " XBD=567 XHG=519 YBD=651 YHG=630>on " XBD=738 XHG=588 YBD=650 YHG=620>civilian " XBD=820 XHG=756 YBD=650 YHG=619>life " XBD=916 XHG=840 YBD=650 YHG=619>and " XBD=1076 XHG=937 YBD=650 YHG=619>morale " XBD=1148 XHG=1096 YBD=659 YHG=619>by " XBD=1308 XHG=1166 YBD=659 YHG=628>power- " XBD=278 XHG=137 YBD=697 YHG=665>bombs. " XBD=374 XHG=328 YBD=695 YHG=664>In " XBD=421 XHG=399 YBD=694 YHG=673>a " XBD=562 XHG=448 YBD=695 YHG=664>letter " XBD=651 XHG=586 YBD=694 YHG=663>Dr. " XBD=840 XHG=680 YBD=695 YHG=655>Stewart " XBD=951 XHG=864 YBD=694 YHG=663>tells " XBD=1060 XHG=974 YBD=695 YHG=663>how " XBD=1123 XHG=1084 YBD=695 YHG=664>in " XBD=1312 XHG=1146 YBD=694 YHG=662>bombed " XBD=302 XHG=136 YBD=741 YHG=708>civilians " XBD=395 XHG=328 YBD=739 YHG=709>the " XBD=578 XHG=417 YBD=739 YHG=717>nervous " XBD=747 XHG=605 YBD=748 YHG=709>system " XBD=846 XHG=776 YBD=738 YHG=717>can " XBD=915 XHG=868 YBD=739 YHG=708>be " XBD=1139 XHG=942 YBD=748 YHG=707>protected " XBD=1308 XHG=1161 YBD=748 YHG=707>against " XBD=197 XHG=135 YBD=785 YHG=754>the " XBD=487 XHG=214 YBD=784 YHG=752>accumulation " XBD=550 XHG=512 YBD=783 YHG=752>of " XBD=731 XHG=573 YBD=792 YHG=752>phobias " XBD=832 XHG=757 YBD=784 YHG=753>and " XBD=1063 XHG=856 YBD=793 YHG=749>increasing " XBD=1233 XHG=1085 YBD=783 YHG=752>tension " XBD=1310 XHG=1257 YBD=792 YHG=752>by " XBD=299 XHG=136 YBD=836 YHG=797>securing " XBD=452 XHG=307 YBD=836 YHG=797>regular " XBD=538 XHG=462 YBD=827 YHG=797>and " XBD=738 XHG=552 YBD=835 YHG=796>adequate " XBD=850 XHG=752 YBD=837 YHG=797>sleep " XBD=954 XHG=878 YBD=827 YHG=797>and " XBD=1144 XHG=965 YBD=839 YHG=796>reducing " XBD=1312 XHG=1155 YBD=836 YHG=797>anxiety " XBD=345 XHG=137 YBD=872 YHG=840>tendencies " XBD=493 XHG=359 YBD=880 YHG=840>during " XBD=654 XHG=504 YBD=880 YHG=840>waking " XBD=790 XHG=664 YBD=872 YHG=840>hours. " XBD=954 XHG=841 YBD=871 YHG=840>From " XBD=1138 XHG=965 YBD=872 YHG=840>America " XBD=1276 XHG=1151 YBD=872 YHG=849>comes " XBD=1312 XHG=1289 YBD=871 YHG=849>a " XBD=284 XHG=137 YBD=925 YHG=883>report 7 on " XBD=592 XHG=362 YBD=925 YHG=884>ergotamine " XBD=767 XHG=605 YBD=916 YHG=885>tartrate " XBD=821 XHG=781 YBD=915 YHG=885>in " XBD=901 XHG=835 YBD=916 YHG=885>the " XBD=1121 XHG=915 YBD=916 YHG=885>treatment " XBD=1176 XHG=1137 YBD=916 YHG=884>of " XBD=1313 XHG=1190 YBD=916 YHG=884>battle " XBD=329 XHG=137 YBD=960 YHG=928>casualties " XBD=402 XHG=361 YBD=959 YHG=929>at " XBD=509 XHG=434 YBD=960 YHG=938>sea. " XBD=648 XHG=559 YBD=960 YHG=928>This " XBD=776 XHG=681 YBD=970 YHG=929>drug " XBD=1026 XHG=806 YBD=961 YHG=928>neutralises " XBD=1313 XHG=1058 YBD=970 YHG=929>sympathetic " XBD=384 XHG=140 YBD=1013 YHG=971>overactivity " XBD=485 XHG=408 YBD=1004 YHG=973>and " XBD=675 XHG=508 YBD=1014 YHG=973>patients " XBD=876 XHG=699 YBD=1013 YHG=974>reported " XBD=986 XHG=900 YBD=1005 YHG=973>that " XBD=1044 XHG=1012 YBD=1005 YHG=974>it " XBD=1181 XHG=1070 YBD=1005 YHG=974>made " XBD=1322 XHG=1206 YBD=1006 YHG=974>them. " XBD=207 XHG=137 YBD=1049 YHG=1017>feel " XBD=376 XHG=229 YBD=1054 YHG=1017>calmer, " XBD=573 XHG=403 YBD=1059 YHG=1019>stronger " XBD=674 XHG=597 YBD=1049 YHG=1017>and " XBD=801 XHG=698 YBD=1049 YHG=1027>more " XBD=867 XHG=826 YBD=1049 YHG=1019>at " XBD=988 XHG=893 YBD=1055 YHG=1027>ease, " XBD=1092 XHG=1016 YBD=1050 YHG=1018>and " XBD=1314 XHG=1116 YBD=1059 YHG=1018>improved " XBD=232 XHG=136 YBD=1093 YHG=1061>their " XBD=464 XHG=266 YBD=1102 YHG=1062>appetites. " XBD=566 XHG=514 YBD=1094 YHG=1061>As " XBD=694 XHG=601 YBD=1094 YHG=1062>with " XBD=965 XHG=728 YBD=1094 YHG=1062>barbiturate " XBD=1184 XHG=1000 YBD=1100 YHG=1063>sedation, " XBD=1314 XHG=1219 YBD=1103 YHG=1072>poor " XBD=268 XHG=139 YBD=1137 YHG=1106>results " XBD=393 XHG=298 YBD=1138 YHG=1115>were " XBD=614 XHG=424 YBD=1138 YHG=1106>obtained- " XBD=673 XHG=633 YBD=1137 YHG=1106>in " XBD=769 XHG=702 YBD=1138 YHG=1107>the " XBD=950 XHG=799 YBD=1139 YHG=1107>chronic " XBD=1149 XHG=980 YBD=1139 YHG=1108>neurotic " XBD=1312 XHG=1181 YBD=1139 YHG=1108>states. " XBD=188 XHG=140 YBD=1182 YHG=1150>As " XBD=229 XHG=208 YBD=1181 YHG=1160>a " XBD=326 XHG=246 YBD=1181 YHG=1150>first " XBD=447 XHG=347 YBD=1188 YHG=1150>dose, " XBD=490 XHG=471 YBD=1182 YHG=1152>3 " XBD=585 XHG=511 YBD=1192 YHG=1159>mg. " XBD=837 XHG=606 YBD=1192 YHG=1151>ergotamine " XBD=1018 XHG=855 YBD=1184 YHG=1153>tartrate " XBD=1113 XHG=1035 YBD=1184 YHG=1161>was " XBD=1243 XHG=1132 YBD=1193 YHG=1151>given " XBD=1315 XHG=1262 YBD=1192 YHG=1152>by " XBD=280 XHG=141 YBD=1231 YHG=1195>mouth, " XBD=375 XHG=299 YBD=1227 YHG=1195>and " XBD=485 XHG=392 YBD=1227 YHG=1195>then " XBD=526 XHG=504 YBD=1226 YHG=1195>2 " XBD=621 XHG=546 YBD=1237 YHG=1205>mg. " XBD=717 XHG=640 YBD=1228 YHG=1205>was " XBD=848 XHG=736 YBD=1237 YHG=1196>given " XBD=980 XHG=866 YBD=1236 YHG=1206>every " XBD=1104 XHG=998 YBD=1227 YHG=1196>three " XBD=1236 XHG=1121 YBD=1228 YHG=1197>hours " XBD=1315 XHG=1255 YBD=1227 YHG=1196>for " XBD=202 XHG=139 YBD=1270 YHG=1240>ten " XBD=345 XHG=241 YBD=1280 YHG=1239>days. " XBD=433 XHG=396 YBD=1271 YHG=1240>It " XBD=565 XHG=475 YBD=1280 YHG=1249>may " XBD=720 XHG=602 YBD=1281 YHG=1250>prove " XBD=935 XHG=760 YBD=1272 YHG=1240>valuable " XBD=1015 XHG=975 YBD=1273 YHG=1241>in " XBD=1313 XHG=1054 YBD=1281 YHG=1240>prophylaxis. " XBD=237 XHG=123 YBD=1315 YHG=1283>Both " XBD=479 XHG=250 YBD=1324 YHG=1284>ergotamine " XBD=568 XHG=492 YBD=1317 YHG=1285>and " XBD=646 XHG=580 YBD=1316 YHG=1286>the " XBD=913 XHG=660 YBD=1317 YHG=1285>barbiturates " XBD=1061 XHG=926 YBD=1317 YHG=1285>reduce " XBD=1140 XHG=1074 YBD=1316 YHG=1285>the " XBD=1314 XHG=1153 YBD=1317 YHG=1286>somatic " XBD=476 XHG=138 YBD=1368 YHG=1328>accompaniments " XBD=535 XHG=496 YBD=1361 YHG=1329>of " XBD=645 XHG=553 YBD=1366 YHG=1330>fear, " XBD=745 XHG=668 YBD=1361 YHG=1329>and " XBD=928 XHG=764 YBD=1361 YHG=1330>without " XBD=1056 XHG=949 YBD=1361 YHG=1330>these " XBD=1316 XHG=1077 YBD=1369 YHG=1329>accompani- " XBD=257 XHG=139 YBD=1405 YHG=1373>ments " XBD=345 XHG=280 YBD=1405 YHG=1373>the " XBD=533 XHG=365 YBD=1405 YHG=1374>emotion " XBD=658 XHG=555 YBD=1405 YHG=1374>itself " XBD=711 XHG=679 YBD=1406 YHG=1374>is " XBD=872 XHG=727 YBD=1406 YHG=1373>robbed " XBD=935 XHG=896 YBD=1406 YHG=1375>of " XBD=1007 XHG=956 YBD=1405 YHG=1374>its " XBD=1163 XHG=1024 YBD=1415 YHG=1383>power. THIOCYANATES IN HYPERTENSION " XBD=236 XHG=185 YBD=1548 YHG=1517>As " XBD=350 XHG=256 YBD=1548 YHG=1516>with " XBD=487 XHG=370 YBD=1558 YHG=1527>many " XBD=616 XHG=508 YBD=1548 YHG=1517>other " XBD=853 XHG=637 YBD=1549 YHG=1517>vaunted &dquo; " XBD=1010 XHG=869 YBD=1548 YHG=1518>cures &dquo; " XBD=1092 XHG=1032 YBD=1548 YHG=1517>for " XBD=1314 XHG=1112 YBD=1557 YHG=1516>hyperten- " XBD=230 XHG=140 YBD=1598 YHG=1562>sion, " XBD=286 XHG=255 YBD=1592 YHG=1561>it " XBD=341 XHG=310 YBD=1593 YHG=1562>is " XBD=525 XHG=368 YBD=1594 YHG=1561>difficult " XBD=648 XHG=547 YBD=1593 YHG=1561>from " XBD=738 XHG=672 YBD=1593 YHG=1562>the " XBD=941 XHG=762 YBD=1593 YHG=1561>evidence " XBD=1007 XHG=965 YBD=1593 YHG=1563>to " XBD=1137 XHG=1034 YBD=1593 YHG=1561>draw " XBD=1316 XHG=1163 YBD=1593 YHG=1561>definite " XBD=366 XHG=141 YBD=1638 YHG=1606>conclusions " XBD=445 XHG=396 YBD=1637 YHG=1616>on " XBD=539 XHG=473 YBD=1638 YHG=1605>the " XBD=680 XHG=568 YBD=1637 YHG=1606>value " XBD=749 XHG=710 YBD=1637 YHG=1606>of " XBD=842 XHG=775 YBD=1637 YHG=1605>the " XBD=1135 XHG=870 YBD=1646 YHG=1606>thiocyanates " XBD=1222 XHG=1165 YBD=1646 YHG=1608>(or " XBD=1317 XHG=1249 YBD=1637 YHG=1605>the " XBD=461 XHG=142 YBD=1691 YHG=1650>sulphocyanides, " XBD=526 XHG=485 YBD=1682 YHG=1660>as " XBD=601 XHG=545 YBD=1682 YHG=1660>we " XBD=715 XHG=621 YBD=1682 YHG=1650>used " XBD=777 XHG=735 YBD=1682 YHG=1651>to " XBD=871 XHG=799 YBD=1681 YHG=1650>call " XBD=1025 XHG=891 YBD=1690 YHG=1650>them). " XBD=1123 XHG=1076 YBD=1681 YHG=1650>In " XBD=1318 XHG=1143 YBD=1682 YHG=1649>America " XBD=289 XHG=143 YBD=1735 YHG=1695>opinion " XBD=331 XHG=302 YBD=1726 YHG=1695>is " XBD=513 XHG=347 YBD=1726 YHG=1695>divided. " XBD=636 XHG=558 YBD=1727 YHG=1694>One " XBD=686 XHG=648 YBD=1726 YHG=1694>of " XBD=762 XHG=696 YBD=1726 YHG=1695>the " XBD=844 XHG=771 YBD=1727 YHG=1695>few " XBD=996 XHG=854 YBD=1726 YHG=1695>British " XBD=1319 XHG=1006 YBD=1735 YHG=1694>investigations " XBD=1319 XHG=1305 YBD=1714 YHG=1695>8 " XBD=303 XHG=141 YBD=1780 YHG=1740>suggests " XBD=417 XHG=328 YBD=1771 YHG=1739>that " XBD=511 XHG=444 YBD=1771 YHG=1739>the " XBD=652 XHG=539 YBD=1780 YHG=1740>drugs " XBD=770 XHG=680 YBD=1779 YHG=1748>may " XBD=973 XHG=798 YBD=1771 YHG=1739>alleviate " XBD=1213 XHG=1000 YBD=1780 YHG=1740>symptoms " XBD=1319 XHG=1242 YBD=1770 YHG=1739>and " XBD=301 XHG=142 YBD=1824 YHG=1784>produce " XBD=372 XHG=331 YBD=1815 YHG=1786>at " XBD=499 XHG=402 YBD=1816 YHG=1784>least " XBD=554 XHG=531 YBD=1815 YHG=1793>a " XBD=804 XHG=584 YBD=1824 YHG=1785>temporary " XBD=902 XHG=833 YBD=1815 YHG=1783>fall " XBD=971 XHG=931 YBD=1815 YHG=1784>in " XBD=1315 XHG=1001 YBD=1824 YHG=1783>blood-pressure. " XBD=384 XHG=143 YBD=1869 YHG=1828>Twenty-five " XBD=632 XHG=417 YBD=1860 YHG=1828>unselected " XBD=777 XHG=663 YBD=1865 YHG=1838>cases, " XBD=848 XHG=808 YBD=1859 YHG=1828>in " XBD=930 XHG=880 YBD=1859 YHG=1828>all " XBD=1000 XHG=961 YBD=1859 YHG=1828>of " XBD=1151 XHG=1028 YBD=1860 YHG=1828>which " XBD=1317 XHG=1181 YBD=1868 YHG=1828>hyper- " XBD=285 XHG=143 YBD=1905 YHG=1873>tension " XBD=399 XHG=320 YBD=1905 YHG=1883>was " XBD=574 XHG=435 YBD=1904 YHG=1873>known " XBD=652 XHG=609 YBD=1904 YHG=1875>to " XBD=786 XHG=685 YBD=1904 YHG=1873>have " XBD=912 XHG=818 YBD=1904 YHG=1873>been " XBD=1092 XHG=941 YBD=1913 YHG=1874>present " XBD=1188 XHG=1128 YBD=1904 YHG=1873>for " XBD=1317 XHG=1228 YBD=1904 YHG=1873>1-12 " XBD=257 XHG=144 YBD=1958 YHG=1927>years, " XBD=381 XHG=286 YBD=1949 YHG=1927>were " XBD=676 XHG=409 YBD=1958 YHG=1917>investigated, " XBD=784 XHG=708 YBD=1949 YHG=1917>and " XBD=912 XHG=815 YBD=1948 YHG=1917>after " XBD=991 XHG=942 YBD=1949 YHG=1927>an " XBD=1143 XHG=1019 YBD=1949 YHG=1917>initial " XBD=1320 XHG=1171 YBD=1949 YHG=1917>control " XBD=269 XHG=144 YBD=2003 YHG=1962>period " XBD=327 XHG=289 YBD=1993 YHG=1962>of " XBD=376 XHG=353 YBD=1993 YHG=1971>a " XBD=505 XHG=400 YBD=1994 YHG=1962>week " XBD=741 XHG=529 YBD=2002 YHG=1962>potassium " XBD=1012 XHG=765 YBD=2002 YHG=1962>thiocyanate " XBD=1114 XHG=1036 YBD=1994 YHG=1971>was " XBD=1251 XHG=1139 YBD=2003 YHG=1961>given " XBD=1316 XHG=1276 YBD=1993 YHG=1962>in " XBD=246 XHG=147 YBD=2039 YHG=2007>doses " XBD=298 XHG=259 YBD=2038 YHG=2006>of " XBD=365 XHG=309 YBD=2038 YHG=2008>O’l g. " XBD=532 XHG=426 YBD=2038 YHG=2007>three " XBD=654 XHG=543 YBD=2038 YHG=2006>times " XBD=689 XHG=668 YBD=2037 YHG=2016>a " XBD=790 XHG=703 YBD=2046 YHG=2006>day. " XBD=892 XHG=840 YBD=2037 YHG=2006>At " XBD=970 XHG=904 YBD=2037 YHG=2006>the " XBD=1056 XHG=982 YBD=2038 YHG=2006>end " XBD=1108 XHG=1069 YBD=2038 YHG=2006>of " XBD=1142 XHG=1120 YBD=2038 YHG=2016>a " XBD=1257 XHG=1152 YBD=2038 YHG=2006>week " XBD=1319 XHG=1270 YBD=2038 YHG=2016>on " XBD=215 XHG=144 YBD=2083 YHG=2051>this " XBD=368 XHG=231 YBD=2092 YHG=2051>dosage " XBD=449 XHG=382 YBD=2082 YHG=2051>the " XBD=585 XHG=462 YBD=2082 YHG=2060>serum " XBD=844 XHG=598 YBD=2091 YHG=2051>thiocyanate " XBD=934 XHG=856 YBD=2082 YHG=2059>was " XBD=1160 XHG=947 YBD=2088 YHG=2050>estimated, " XBD=1253 XHG=1176 YBD=2083 YHG=2051>and " XBD=1318 XHG=1269 YBD=2083 YHG=2061>on " XBD=206 XHG=145 YBD=2128 YHG=2095>the " XBD=324 XHG=225 YBD=2127 YHG=2095>basis " XBD=387 XHG=348 YBD=2127 YHG=2096>of " XBD=475 XHG=408 YBD=2127 YHG=2095>the " XBD=660 XHG=497 YBD=2136 YHG=2095>findings " XBD=749 XHG=681 YBD=2127 YHG=2095>the " XBD=939 XHG=771 YBD=2136 YHG=2095>patients " XBD=1073 XHG=961 YBD=2126 YHG=2095>could " XBD=1141 XHG=1095 YBD=2127 YHG=2095>be " XBD=1320 XHG=1165 YBD=2127 YHG=2095>divided " XBD=221 XHG=145 YBD=2172 YHG=2140>into " XBD=342 XHG=237 YBD=2172 YHG=2140>three " XBD=462 XHG=360 YBD=2171 YHG=2140>main " XBD=779 XHG=481 YBD=2181 YHG=2140>groups-those " XBD=835 XHG=795 YBD=2170 YHG=2139>in " XBD=979 XHG=852 YBD=2171 YHG=2139>whom " XBD=1062 XHG=996 YBD=2171 YHG=2139>the " XBD=1204 XHG=1080 YBD=2174 YHG=2149>serum " XBD=1319 XHG=1221 YBD=2171 YHG=2136>thio- " XBD=301 XHG=146 YBD=2225 YHG=2186>cyanate " XBD=391 XHG=314 YBD=2216 YHG=2194>was " XBD=478 XHG=407 YBD=2216 YHG=2184>less " XBD=591 XHG=494 YBD=2215 YHG=2184>than " XBD=630 XHG=608 YBD=2215 YHG=2186>4 " XBD=736 XHG=647 YBD=2225 YHG=2193>mg., " XBD=921 XHG=752 YBD=2216 YHG=2184>between " XBD=961 XHG=939 YBD=2215 YHG=2185>4 " XBD=1055 XHG=978 YBD=2216 YHG=2184>and " XBD=1114 XHG=1075 YBD=2215 YHG=2186>I mg., " XBD=1320 XHG=1240 YBD=2216 YHG=2184>and " XBD=230 XHG=147 YBD=2261 YHG=2239>over " XBD=287 XHG=247 YBD=2260 YHG=2231>11 " XBD=377 XHG=304 YBD=2270 YHG=2238>mg. " XBD=460 XHG=393 YBD=2269 YHG=2238>per " XBD=664 XHG=478 YBD=2261 YHG=2230>100 c.cm. " XBD=761 XHG=716 YBD=2260 YHG=2229>In " XBD=842 XHG=775 YBD=2260 YHG=2229>the " XBD=938 XHG=857 YBD=2260 YHG=2228>first " XBD=1072 XHG=953 YBD=2269 YHG=2238>group " XBD=1229 XHG=1090 YBD=2269 YHG=2229>dosage " XBD=1320 XHG=1242 YBD=2261 YHG=2238>was " XBD=336 XHG=146 YBD=2314 YHG=2274>gradually " XBD=550 XHG=358 YBD=2305 YHG=2273>increased " XBD=672 XHG=574 YBD=2304 YHG=2273>until " XBD=719 XHG=696 YBD=2304 YHG=2282>a " XBD=866 XHG=743 YBD=2305 YHG=2282>serum " XBD=1136 XHG=890 YBD=2313 YHG=2273>thiocyanate " XBD=1256 XHG=1158 YBD=2305 YHG=2273>level " XBD=1320 XHG=1281 YBD=2305 YHG=2273>of " XBD=231 XHG=146 YBD=2349 YHG=2319>5-12 " XBD=321 XHG=247 YBD=2358 YHG=2328>mg. " XBD=415 XHG=337 YBD=2349 YHG=2328>was " XBD=638 XHG=433 YBD=2356 YHG=2318>obtained ; " XBD=708 XHG=669 YBD=2349 YHG=2318>in " XBD=790 XHG=723 YBD=2349 YHG=2317>the " XBD=945 XHG=806 YBD=2349 YHG=2318>second " XBD=1080 XHG=961 YBD=2358 YHG=2327>group " XBD=1164 XHG=1097 YBD=2349 YHG=2318>the " XBD=1321 XHG=1182 YBD=2359 YHG=2318>dosage " XBD=216 XHG=144 YBD=2393 YHG=2371>was " XBD=393 XHG=232 YBD=2393 YHG=2362>reduced " XBD=548 XHG=412 YBD=2402 YHG=2362>during " XBD=631 XHG=564 YBD=2393 YHG=2362>the " XBD=787 XHG=649 YBD=2393 YHG=2362>second " XBD=908 XHG=804 YBD=2393 YHG=2362>week " XBD=967 XHG=926 YBD=2393 YHG=2364>to |>" XBD=1046 XHG=988 YBD=2393 YHG=2362>0’2 " XBD=1100 XHG=1065 YBD=2402 YHG=2372>g. " XBD=1225 XHG=1122 YBD=2401 YHG=2362>daily " XBD=1321 XHG=1244 YBD=2393 YHG=2362>and " XBD=405 XHG=146 YBD=2446 YHG=2406>subsequently " XBD=644 XHG=435 YBD=2437 YHG=2406>controlled " XBD=726 XHG=674 YBD=2446 YHG=2406>by " XBD=993 XHG=757 YBD=2438 YHG=2406>estimations " XBD=1064 XHG=1025 YBD=2437 YHG=2406>of " XBD=1166 XHG=1100 YBD=2437 YHG=2406>the " XBD=1320 XHG=1198 YBD=2437 YHG=2415>serum " XBD=407 XHG=144 YBD=2491 YHG=2450>thiocyanate ; " XBD=476 XHG=436 YBD=2481 YHG=2450>in " XBD=559 XHG=492 YBD=2482 YHG=2450>the " XBD=678 XHG=574 YBD=2482 YHG=2450>third " XBD=814 XHG=694 YBD=2491 YHG=2460>group " XBD=862 XHG=831 YBD=2482 YHG=2451>it " XBD=955 XHG=877 YBD=2482 YHG=2460>was " XBD=1133 XHG=970 YBD=2482 YHG=2450>reduced " XBD=1191 XHG=1149 YBD=2482 YHG=2452>to 0- " XBD=1320 XHG=1249 YBD=2491 YHG=2452>1 g. " XBD=225 XHG=145 YBD=2527 YHG=2495>four " XBD=352 XHG=242 YBD=2527 YHG=2495>times " XBD=396 XHG=372 YBD=2526 YHG=2504>a " XBD=518 XHG=413 YBD=2527 YHG=2494>week " XBD=614 XHG=537 YBD=2526 YHG=2495>and " XBD=726 XHG=633 YBD=2526 YHG=2495>then " XBD=958 XHG=746 YBD=2536 YHG=2494>cautiously " XBD=1101 XHG=976 YBD=2526 YHG=2494>raised " XBD=1322 XHG=1121 YBD=2536 YHG=2494>according " XBD=184 XHG=146 YBD=2571 YHG=2541>to " XBD=266 XHG=203 YBD=2571 YHG=2539>the " XBD=408 XHG=286 YBD=2571 YHG=2549>serum " XBD=673 XHG=426 YBD=2580 YHG=2539>thiocyanate " XBD=819 XHG=691 YBD=2572 YHG=2539>levels. " XBD=971 XHG=871 YBD=2571 YHG=2538>Once " XBD=1056 XHG=989 YBD=2571 YHG=2539>the " XBD=1224 XHG=1075 YBD=2580 YHG=2539>patient " XBD=1320 XHG=1242 YBD=2572 YHG=2549>was " XBD=362 XHG=149 YBD=2624 YHG=2584>discharged " XBD=472 XHG=372 YBD=2616 YHG=2584>from " XBD=668 XHG=489 YBD=2624 YHG=2583>hospital, " XBD=807 XHG=683 YBD=2616 YHG=2593>serum " XBD=1071 XHG=825 YBD=2624 YHG=2585>thiocyanate " XBD=1320 XHG=1084 YBD=2616 YHG=2584>estimations " XBD=235 XHG=147 YBD=2660 YHG=2637>were " XBD=391 XHG=248 YBD=2660 YHG=2628>carried " XBD=472 XHG=406 YBD=2660 YHG=2630>out " XBD=556 XHG=485 YBD=2660 YHG=2628>less " XBD=688 XHG=572 YBD=2665 YHG=2628>often, " XBD=782 XHG=705 YBD=2660 YHG=2629>and " XBD=834 XHG=794 YBD=2660 YHG=2629>in " XBD=948 XHG=849 YBD=2660 YHG=2630>most " XBD=1065 XHG=963 YBD=2660 YHG=2638>cases " XBD=1145 XHG=1079 YBD=2660 YHG=2629>the " XBD=1319 XHG=1158 YBD=2668 YHG=2629>require- " XBD=262 XHG=147 YBD=2704 YHG=2675>ments " XBD=325 XHG=287 YBD=2703 YHG=2672>of " XBD=558 XHG=346 YBD=2713 YHG=2673>potassium " XBD=828 XHG=581 YBD=2713 YHG=2672>thiocyanate " XBD=946 XHG=850 YBD=2705 YHG=2682>were " XBD=1088 XHG=967 YBD=2704 YHG=2672>found " XBD=1152 XHG=1111 YBD=2704 YHG=2674>to " XBD=1320 XHG=1176 YBD=2704 YHG=2673>remain " XBD=334 XHG=146 YBD=2757 YHG=2712>relatively " XBD=552 XHG=364 YBD=2748 YHG=2719>constant. " XBD=654 XHG=606 YBD=2748 YHG=2717>Of " XBD=749 XHG=682 YBD=2748 YHG=2717>the " XBD=824 XHG=779 YBD=2749 YHG=2718>25 " XBD=1021 XHG=853 YBD=2758 YHG=2718>patients " XBD=1316 XHG=1049 YBD=2757 YHG=2717>investigated, " XBD=186 XHG=150 YBD=2791 YHG=2762>11 " XBD=355 XHG=208 YBD=2792 YHG=2760>showed " XBD=398 XHG=376 YBD=2792 YHG=2771>a " XBD=484 XHG=416 YBD=2792 YHG=2761>fall " XBD=543 XHG=504 YBD=2793 YHG=2762>of " XBD=613 XHG=568 YBD=2793 YHG=2762>40 " XBD=724 XHG=634 YBD=2792 YHG=2771>mm. " XBD=809 XHG=747 YBD=2802 YHG=2761>Hg " XBD=871 XHG=830 YBD=2793 YHG=2772>or " XBD=993 XHG=891 YBD=2793 YHG=2772>more " XBD=1051 XHG=1012 YBD=2793 YHG=2762>in " XBD=1141 XHG=1075 YBD=2793 YHG=2761>the " XBD=1320 XHG=1166 YBD=2801 YHG=2760>systolic " XBD=307 XHG=146 YBD=2845 YHG=2814>pressure " XBD=403 XHG=326 YBD=2837 YHG=2805>and " XBD=468 XHG=423 YBD=2837 YHG=2806>20 " XBD=578 XHG=488 YBD=2837 YHG=2816>mm. " XBD=642 XHG=600 YBD=2837 YHG=2816>or " XBD=764 XHG=662 YBD=2837 YHG=2815>more " XBD=822 XHG=783 YBD=2837 YHG=2806>in " XBD=907 XHG=841 YBD=2837 YHG=2806>the " XBD=1101 XHG=929 YBD=2837 YHG=2806>diastolic " XBD=1313 XHG=1120 YBD=2846 YHG=2815>pressure ; " XBD=167 XHG=148 YBD=2880 YHG=2851>6 " XBD=331 XHG=185 YBD=2881 YHG=2849>showed " XBD=500 XHG=351 YBD=2881 YHG=2850>smaller " XBD=617 XHG=517 YBD=2887 YHG=2850>falls; " XBD=744 XHG=635 YBD=2881 YHG=2849>while " XBD=786 XHG=765 YBD=2881 YHG=2852>8 " XBD=903 XHG=806 YBD=2891 YHG=2860>gave " XBD=971 XHG=921 YBD=2881 YHG=2860>no " XBD=1179 XHG=991 YBD=2891 YHG=2860>response. " XBD=1268 XHG=1231 YBD=2881 YHG=2850>It " XBD=1318 XHG=1286 YBD=2881 YHG=2850>is " XBD=350 XHG=148 YBD=2934 YHG=2893>significant " XBD=460 XHG=372 YBD=2925 YHG=2894>that " XBD=523 XHG=484 YBD=2925 YHG=2895>of " XBD=611 XHG=544 YBD=2926 YHG=2894>the " XBD=679 XHG=638 YBD=2924 YHG=2894>12 " XBD=869 XHG=701 YBD=2934 YHG=2894>patients " XBD=984 XHG=891 YBD=2926 YHG=2895>with " XBD=1056 XHG=1007 YBD=2926 YHG=2904>no " XBD=1257 XHG=1079 YBD=2926 YHG=2894>evidence " XBD=1321 XHG=1281 YBD=2926 YHG=2894>of " XBD=301 XHG=148 YBD=2978 YHG=2938>activity " XBD=549 XHG=311 YBD=2978 YHG=2938>(hsematuria " XBD=606 XHG=565 YBD=2969 YHG=2948>or " XBD=757 XHG=619 YBD=2970 YHG=2938>retinal |>" XBD=1061 XHG=770 YBD=2979 YHG=2938>haemorrhages) " XBD=1162 XHG=1074 YBD=2979 YHG=2939>only " XBD=1194 XHG=1177 YBD=2969 YHG=2940>1 " XBD=1321 XHG=1205 YBD=2970 YHG=2938>failed " XBD=185 XHG=147 YBD=3013 YHG=2983>to " XBD=312 XHG=212 YBD=3014 YHG=2982>show " XBD=361 XHG=339 YBD=3013 YHG=2992>a " XBD=454 XHG=386 YBD=3013 YHG=2982>fall " XBD=520 XHG=481 YBD=3014 YHG=2983>of " XBD=593 XHG=546 YBD=3014 YHG=2984>40 " XBD=710 XHG=619 YBD=3014 YHG=2992>mm. " XBD=776 XHG=736 YBD=3013 YHG=2982>in " XBD=956 XHG=802 YBD=3022 YHG=2983>systolic " XBD=1061 XHG=984 YBD=3014 YHG=2983>and " XBD=1134 XHG=1088 YBD=3015 YHG=2983>20 " XBD=1250 XHG=1160 YBD=3014 YHG=2992>mm. " XBD=1318 XHG=1278 YBD=3013 YHG=2982>in " XBD=312 XHG=149 YBD=3058 YHG=3026>diastolic " XBD=514 XHG=333 YBD=3066 YHG=3036>pressure, " XBD=702 XHG=536 YBD=3058 YHG=3027>whereas " XBD=765 XHG=726 YBD=3058 YHG=3027>of " XBD=853 XHG=787 YBD=3058 YHG=3026>the " XBD=920 XHG=880 YBD=3058 YHG=3027>12 " XBD=1111 XHG=944 YBD=3067 YHG=3027>patients " XBD=1227 XHG=1133 YBD=3060 YHG=3027>with " XBD=1321 XHG=1250 YBD=3058 YHG=3036>one " XBD=187 XHG=149 YBD=3101 YHG=3079>or " XBD=292 XHG=199 YBD=3102 YHG=3071>both " XBD=345 XHG=307 YBD=3102 YHG=3071>of " XBD=463 XHG=358 YBD=3103 YHG=3071>these " XBD=577 XHG=477 YBD=3112 YHG=3072>signs " XBD=631 XHG=592 YBD=3103 YHG=3072>of " XBD=807 XHG=646 YBD=3111 YHG=3071>activity " XBD=918 XHG=820 YBD=3103 YHG=3080>none " XBD=1085 XHG=932 YBD=3103 YHG=3071>showed " XBD=1193 XHG=1099 YBD=3103 YHG=3072>such " XBD=1229 XHG=1207 YBD=3102 YHG=3081>a " XBD=1322 XHG=1242 YBD=3103 YHG=3071>fall. " XBD=417 XHG=150 YBD=3155 YHG=3113>Symptomatic " XBD=715 XHG=437 YBD=3155 YHG=3116>improvement " XBD=813 XHG=735 YBD=3147 YHG=3125>was " XBD=938 XHG=835 YBD=3147 YHG=3125>more " XBD=1120 XHG=959 YBD=3156 YHG=3116>striking " XBD=1236 XHG=1139 YBD=3147 YHG=3116>than " XBD=1324 XHG=1257 YBD=3147 YHG=3116>the " XBD=211 XHG=147 YBD=3189 YHG=3158>fall " XBD=266 XHG=228 YBD=3189 YHG=3159>in " XBD=609 XHG=286 YBD=3199 YHG=3159>blood-pressure ; " XBD=736 XHG=646 YBD=3191 YHG=3159>thus " XBD=803 XHG=761 YBD=3190 YHG=3161>14 " XBD=892 XHG=825 YBD=3190 YHG=3161>out " XBD=954 XHG=915 YBD=3190 YHG=3159>of " XBD=1019 XHG=977 YBD=3190 YHG=3161>17 " XBD=1209 XHG=1041 YBD=3198 YHG=3160>patients " XBD=1322 XHG=1228 YBD=3191 YHG=3159>with " XBD=331 XHG=147 YBD=3233 YHG=3201>headache " XBD=519 XHG=349 YBD=3234 YHG=3203>received " XBD=651 XHG=536 YBD=3240 YHG=3204>relief, " XBD=712 XHG=672 YBD=3234 YHG=3212>as " XBD=798 XHG=733 YBD=3234 YHG=3203>did " XBD=839 XHG=818 YBD=3233 YHG=3205>5 " XBD=926 XHG=859 YBD=3234 YHG=3204>out " XBD=985 XHG=947 YBD=3233 YHG=3203>of " XBD=1026 XHG=1006 YBD=3233 YHG=3204>6 " XBD=1212 XHG=1045 YBD=3242 YHG=3203>patients " XBD=1324 XHG=1230 YBD=3234 YHG=3203>with " XBD=300 XHG=149 YBD=3286 YHG=3246>vertigo, " XBD=410 XHG=334 YBD=3277 YHG=3246>and " XBD=466 XHG=444 YBD=3278 YHG=3248>5 " XBD=568 XHG=502 YBD=3278 YHG=3248>out " XBD=643 XHG=604 YBD=3278 YHG=3247>of " XBD=698 XHG=678 YBD=3278 YHG=3249>8 " XBD=900 XHG=732 YBD=3286 YHG=3246>patients " XBD=1027 XHG=933 YBD=3278 YHG=3246>with " XBD=1322 XHG=1060 YBD=3286 YHG=3246>palpitations. " XBD=384 XHG=149 YBD=3329 YHG=3288>Presumably " XBD=571 XHG=412 YBD=3321 YHG=3290>because " XBD=640 XHG=601 YBD=3322 YHG=3291>of " XBD=740 XHG=674 YBD=3322 YHG=3291>the " XBD=916 XHG=776 YBD=3322 YHG=3290>careful " XBD=1092 XHG=945 YBD=3321 YHG=3290>control " XBD=1171 XHG=1119 YBD=3329 YHG=3289>by " XBD=1323 XHG=1200 YBD=3321 YHG=3299>serum 6. Slater, P., Sargant, W. and Glen, M. Lancet, 1942, i, 676. 7. Heath, R. G. and Powdermaker, F. J. Amer. med. Ass. 1944, 125, 111. 8. D’Silva, J. L. and Evans, G. Brit. J. Urol. 1944, 16, 1. " XBD=1612 XHG=1365 YBD=220 YHG=180>thiocyanate " XBD=1872 XHG=1623 YBD=216 YHG=180>estimations, " XBD=1988 XHG=1885 YBD=211 YHG=180>toxic " XBD=2127 XHG=2000 YBD=212 YHG=181>effects " XBD=2239 XHG=2144 YBD=213 YHG=191>were " XBD=2344 XHG=2250 YBD=218 YHG=191>rare, " XBD=2552 XHG=2358 YBD=221 YHG=182>occurring " XBD=1405 XHG=1365 YBD=256 YHG=225>in " XBD=1508 XHG=1418 YBD=264 YHG=225>only " XBD=1541 XHG=1520 YBD=254 YHG=225>2 " XBD=1733 XHG=1553 YBD=263 YHG=225>patients. " XBD=1864 XHG=1786 YBD=255 YHG=223>One " XBD=1917 XHG=1878 YBD=254 YHG=224>of " XBD=2038 XHG=1931 YBD=254 YHG=224>these " XBD=2116 XHG=2048 YBD=255 YHG=224>felt " XBD=2355 XHG=2128 YBD=265 YHG=225>excessively " XBD=2464 XHG=2365 YBD=256 YHG=225>tired " XBD=2553 XHG=2477 YBD=255 YHG=225>and " XBD=1586 XHG=1366 YBD=306 YHG=268>nauseated, " XBD=1676 XHG=1600 YBD=299 YHG=268>and " XBD=1930 XHG=1692 YBD=308 YHG=267>complained " XBD=1981 XHG=1942 YBD=298 YHG=268>of " XBD=2104 XHG=1995 YBD=306 YHG=267>pains " XBD=2158 XHG=2119 YBD=298 YHG=267>in " XBD=2239 XHG=2173 YBD=299 YHG=268>the " XBD=2330 XHG=2252 YBD=309 YHG=267>legs " XBD=2419 XHG=2342 YBD=299 YHG=268>and " XBD=2553 XHG=2433 YBD=307 YHG=268>impo- " XBD=1474 XHG=1366 YBD=344 YHG=314>tence " XBD=1601 XHG=1492 YBD=344 YHG=312>when " XBD=1691 XHG=1625 YBD=343 YHG=312>the " XBD=1838 XHG=1714 YBD=343 YHG=321>serum |>" XBD=2108 XHG=1861 YBD=351 YHG=311>thiocyanate " XBD=2207 XHG=2129 YBD=342 YHG=321>was " XBD=2277 XHG=2235 YBD=342 YHG=313>18 " XBD=2375 XHG=2301 YBD=352 YHG=321>mg. " XBD=2461 XHG=2393 YBD=351 YHG=321>per " XBD=2554 XHG=2488 YBD=342 YHG=313>100 " XBD=1500 XHG=1368 YBD=394 YHG=366>c.cm. ; " XBD=1606 XHG=1540 YBD=387 YHG=356>the " XBD=1741 XHG=1632 YBD=387 YHG=356>other " XBD=2004 XHG=1766 YBD=395 YHG=355>complained " XBD=2069 XHG=2031 YBD=386 YHG=355>of " XBD=2273 XHG=2092 YBD=386 YHG=354>tiredness " XBD=2377 XHG=2300 YBD=386 YHG=356>and " XBD=2554 XHG=2400 YBD=386 YHG=364>nausea. " XBD=1430 XHG=1368 YBD=431 YHG=399>All " XBD=1527 XHG=1450 YBD=431 YHG=400>this " XBD=1580 XHG=1549 YBD=431 YHG=400>is " XBD=1845 XHG=1603 YBD=439 YHG=400>satisfactory " XBD=1910 XHG=1869 YBD=430 YHG=409>as " XBD=1995 XHG=1935 YBD=430 YHG=400>far " XBD=2059 XHG=2018 YBD=430 YHG=408>as " XBD=2116 XHG=2084 YBD=429 YHG=399>it " XBD=2238 XHG=2138 YBD=439 YHG=408>goes, " XBD=2331 XHG=2261 YBD=430 YHG=398>but " XBD=2420 XHG=2352 YBD=430 YHG=399>the " XBD=2555 XHG=2445 YBD=430 YHG=399>series " XBD=1399 XHG=1368 YBD=474 YHG=443>is " XBD=1504 XHG=1412 YBD=483 YHG=452>very " XBD=1627 XHG=1517 YBD=475 YHG=444>small " XBD=1716 XHG=1639 YBD=475 YHG=444>and " XBD=1783 XHG=1727 YBD=475 YHG=453>we " XBD=1895 XHG=1796 YBD=475 YHG=443>have " XBD=1956 XHG=1907 YBD=474 YHG=453>no " XBD=2148 XHG=1970 YBD=474 YHG=443>evidence " XBD=2200 XHG=2161 YBD=473 YHG=442>of " XBD=2299 XHG=2212 YBD=473 YHG=442>how " XBD=2399 XHG=2308 YBD=482 YHG=443>long " XBD=2476 XHG=2410 YBD=473 YHG=443>the " XBD=2556 XHG=2488 YBD=473 YHG=443>fall " XBD=1408 XHG=1369 YBD=517 YHG=487>in " XBD=1589 XHG=1420 YBD=526 YHG=496>pressure " XBD=1630 XHG=1600 YBD=518 YHG=488>is " XBD=1878 XHG=1644 YBD=519 YHG=487>maintained " XBD=1933 XHG=1891 YBD=518 YHG=497>or " XBD=2047 XHG=1943 YBD=518 YHG=487>what " XBD=2089 XHG=2058 YBD=517 YHG=487>is " XBD=2150 XHG=2101 YBD=517 YHG=486>its " XBD=2271 XHG=2162 YBD=517 YHG=485>effect " XBD=2333 XHG=2285 YBD=516 YHG=495>on " XBD=2553 XHG=2345 YBD=526 YHG=487>prognosis. " XBD=1531 XHG=1370 YBD=561 YHG=531>Further " XBD=1574 XHG=1543 YBD=561 YHG=531>it " XBD=1723 XHG=1587 YBD=562 YHG=531>should " XBD=1782 XHG=1736 YBD=562 YHG=531>be " XBD=1912 XHG=1794 YBD=562 YHG=531>noted " XBD=2012 XHG=1924 YBD=562 YHG=531>that " XBD=2165 XHG=2025 YBD=562 YHG=529>careful " XBD=2324 XHG=2178 YBD=561 YHG=529>control " XBD=2365 XHG=2335 YBD=560 YHG=530>is " XBD=2554 XHG=2382 YBD=569 YHG=529>required " XBD=1422 XHG=1369 YBD=614 YHG=575>by " XBD=1659 XHG=1438 YBD=615 YHG=574>laboratory " XBD=1853 XHG=1677 YBD=607 YHG=575>methods " XBD=1958 XHG=1870 YBD=606 YHG=575>that " XBD=2045 XHG=1978 YBD=606 YHG=580>are " XBD=2205 XHG=2056 YBD=614 YHG=574>usually " XBD=2290 XHG=2222 YBD=605 YHG=575>not " XBD=2495 XHG=2309 YBD=605 YHG=573>available " XBD=2554 XHG=2512 YBD=605 YHG=575>to " XBD=1437 XHG=1349 YBD=649 YHG=614>the " XBD=1704 XHG=1457 YBD=658 YHG=619>practitioner " XBD=1766 XHG=1725 YBD=650 YHG=629>or " XBD=1881 XHG=1785 YBD=651 YHG=629>even " XBD=1941 XHG=1900 YBD=651 YHG=621>to " XBD=2079 XHG=1963 YBD=659 YHG=629>many " XBD=2209 XHG=2099 YBD=650 YHG=618>small " XBD=2425 XHG=2230 YBD=658 YHG=617>hospitals. TREATMENT OF BACTERIAL ENDOCARDITIS " XBD=1553 XHG=1422 YBD=784 YHG=752>WHEN " XBD=1685 XHG=1575 YBD=783 YHG=751>faced " XBD=1799 XHG=1705 YBD=783 YHG=751>with " XBD=1870 XHG=1820 YBD=783 YHG=761>an " XBD=2029 XHG=1892 YBD=785 YHG=752>almost " XBD=2263 XHG=2050 YBD=793 YHG=752>invariably " XBD=2380 XHG=2282 YBD=783 YHG=751>fatal " XBD=2557 XHG=2402 YBD=788 YHG=751>disease, " XBD=1442 XHG=1375 YBD=828 YHG=796>the " XBD=1659 XHG=1460 YBD=836 YHG=795>physician " XBD=1708 XHG=1677 YBD=827 YHG=796>is " XBD=1829 XHG=1728 YBD=836 YHG=795>right " XBD=1891 XHG=1849 YBD=827 YHG=798>to " XBD=1975 XHG=1910 YBD=836 YHG=798>try " XBD=2108 XHG=1994 YBD=837 YHG=806>every " XBD=2210 XHG=2127 YBD=829 YHG=806>new " XBD=2395 XHG=2227 YBD=836 YHG=806>weapon, " XBD=2512 XHG=2417 YBD=827 YHG=805>even " XBD=2561 XHG=2531 YBD=827 YHG=796>if " XBD=1406 XHG=1375 YBD=872 YHG=841>it " XBD=1566 XHG=1431 YBD=871 YHG=840>carries " XBD=1639 XHG=1589 YBD=871 YHG=840>its " XBD=1747 XHG=1664 YBD=871 YHG=849>own " XBD=1878 XHG=1770 YBD=871 YHG=840>risks. " XBD=2007 XHG=1929 YBD=872 YHG=840>But " XBD=2069 XHG=2029 YBD=872 YHG=841>in " XBD=2275 XHG=2092 YBD=881 YHG=841>assessing " XBD=2364 XHG=2298 YBD=872 YHG=841>the " XBD=2498 XHG=2387 YBD=871 YHG=840>value " XBD=2562 XHG=2522 YBD=871 YHG=840>of " XBD=1469 XHG=1377 YBD=916 YHG=884>such " XBD=1673 XHG=1497 YBD=924 YHG=887>weapons " XBD=1741 XHG=1700 YBD=915 YHG=884>in " XBD=1951 XHG=1769 YBD=916 YHG=884>subacute " XBD=2160 XHG=1979 YBD=916 YHG=884>bacterial " XBD=2439 XHG=2189 YBD=917 YHG=884>endocarditis " XBD=2500 XHG=2468 YBD=916 YHG=885>it " XBD=2561 XHG=2528 YBD=916 YHG=884>is " XBD=1634 XHG=1375 YBD=969 YHG=928>unjustifiable " XBD=1690 XHG=1650 YBD=960 YHG=929>to " XBD=1833 XHG=1706 YBD=969 YHG=928>ignore " XBD=1916 XHG=1849 YBD=960 YHG=928>the " XBD=2019 XHG=1929 YBD=970 YHG=928>long " XBD=2244 XHG=2032 YBD=961 YHG=930>remissions " XBD=2347 XHG=2259 YBD=961 YHG=930>that " XBD=2433 XHG=2363 YBD=961 YHG=939>can " XBD=2561 XHG=2450 YBD=961 YHG=938>occur " XBD=1569 XHG=1375 YBD=1006 YHG=973>whatever " XBD=1802 XHG=1594 YBD=1005 YHG=974>treatment " XBD=1860 XHG=1828 YBD=1005 YHG=973>is " XBD=2085 XHG=1888 YBD=1014 YHG=973>adopted. " XBD=2155 XHG=2118 YBD=1005 YHG=973>It " XBD=2213 XHG=2182 YBD=1005 YHG=974>is " XBD=2326 XHG=2240 YBD=1006 YHG=984>now " XBD=2425 XHG=2350 YBD=1006 YHG=974>five " XBD=2570 XHG=2450 YBD=1015 YHG=979>years’ " XBD=1477 XHG=1377 YBD=1050 YHG=1019>since " XBD=1579 XHG=1511 YBD=1049 YHG=1018>the " XBD=1873 XHG=1613 YBD=1050 YHG=1017>introduction " XBD=1949 XHG=1909 YBD=1048 YHG=1017>of " XBD=2007 XHG=1984 YBD=1049 YHG=1027>a " XBD=2240 XHG=2042 YBD=1058 YHG=1017>relatively " XBD=2367 XHG=2273 YBD=1059 YHG=1028>pure " XBD=2560 XHG=2402 YBD=1060 YHG=1018>heparin " XBD=1582 XHG=1375 YBD=1104 YHG=1062>permitted " XBD=1814 XHG=1613 YBD=1095 YHG=1062>American workers " XBD=2098 XHG=2011 YBD=1094 YHG=1062>1 to " XBD=2195 XHG=2130 YBD=1102 YHG=1063>try " XBD=2292 XHG=2226 YBD=1094 YHG=1062>the " XBD=2429 XHG=2320 YBD=1095 YHG=1063>effect " XBD=2502 XHG=2463 YBD=1095 YHG=1063>of " XBD=2557 XHG=2534 YBD=1095 YHG=1073>a " XBD=1635 XHG=1378 YBD=1139 YHG=1107>combination " XBD=1699 XHG=1660 YBD=1138 YHG=1107>of " XBD=2027 XHG=1721 YBD=1148 YHG=1107>sulphonamides " XBD=2127 XHG=2050 YBD=1138 YHG=1106>and " XBD=2317 XHG=2148 YBD=1146 YHG=1107>heparin, " XBD=2464 XHG=2341 YBD=1139 YHG=1107>which " XBD=2564 XHG=2485 YBD=1139 YHG=1108>had " XBD=1537 XHG=1378 YBD=1183 YHG=1152>obvious " XBD=1772 XHG=1550 YBD=1183 YHG=1152>theoretical " XBD=2036 XHG=1784 YBD=1192 YHG=1151>possibilities, " XBD=2091 XHG=2051 YBD=1183 YHG=1151>in " XBD=2285 XHG=2104 YBD=1182 YHG=1151>bacterial " XBD=2561 XHG=2297 YBD=1184 YHG=1151>endocarditis. " XBD=1575 XHG=1381 YBD=1237 YHG=1196>Repeated |>" XBD=1794 XHG=1583 YBD=1237 YHG=1196>warnings 2 of " XBD=1931 XHG=1865 YBD=1227 YHG=1196>the " XBD=2106 XHG=1948 YBD=1236 YHG=1195>dangers " XBD=2158 XHG=2119 YBD=1226 YHG=1195>of " XBD=2330 XHG=2173 YBD=1235 YHG=1195>heparin " XBD=2507 XHG=2345 YBD=1237 YHG=1196>therapy " XBD=2563 XHG=2522 YBD=1228 YHG=1196>in " XBD=1472 XHG=1380 YBD=1272 YHG=1240>such " XBD=1592 XHG=1489 YBD=1272 YHG=1250>cases " XBD=1793 XHG=1608 YBD=1278 YHG=1240>followed, " XBD=1884 XHG=1812 YBD=1272 YHG=1241>but " XBD=1932 XHG=1900 YBD=1272 YHG=1240>it " XBD=2153 XHG=1950 YBD=1272 YHG=1239>continued " XBD=2211 XHG=2170 YBD=1271 YHG=1241>to " XBD=2276 XHG=2229 YBD=1271 YHG=1240>be " XBD=2385 XHG=2292 YBD=1272 YHG=1240>used " XBD=2561 XHG=2403 YBD=1273 YHG=1240>because " XBD=1408 XHG=1377 YBD=1317 YHG=1286>it " XBD=1516 XHG=1438 YBD=1317 YHG=1294>was " XBD=1613 XHG=1547 YBD=1316 YHG=1284>the " XBD=1734 XHG=1644 YBD=1325 YHG=1284>only " XBD=1874 XHG=1762 YBD=1325 YHG=1285>hope. " XBD=2048 XHG=1925 YBD=1316 YHG=1284>Cooke " XBD=2155 XHG=2078 YBD=1316 YHG=1283>and Taylor " XBD=2448 XHG=2331 YBD=1316 YHG=1283>3 last " XBD=2565 XHG=2472 YBD=1325 YHG=1294>year " XBD=1621 XHG=1379 YBD=1369 YHG=1328>reported ’on " XBD=1685 XHG=1639 YBD=1360 YHG=1329>20 " XBD=1805 XHG=1702 YBD=1361 YHG=1338>cases " XBD=1970 XHG=1821 YBD=1361 YHG=1329>treated " XBD=2079 XHG=1985 YBD=1361 YHG=1328>with " XBD=2411 XHG=2095 YBD=1369 YHG=1329>sulphonamides, " XBD=2469 XHG=2429 YBD=1360 YHG=1329>in " XBD=2566 XHG=2487 YBD=1361 YHG=1329>5 -of " XBD=1500 XHG=1377 YBD=1405 YHG=1374>which " XBD=1623 XHG=1528 YBD=1414 YHG=1373>they " XBD=1741 XHG=1645 YBD=1406 YHG=1383>were " XBD=1964 XHG=1766 YBD=1405 YHG=1373>combined " XBD=2080 XHG=1987 YBD=1406 YHG=1373>with " XBD=2272 XHG=2103 YBD=1414 YHG=1373>heparin. " XBD=2383 XHG=2322 YBD=1405 YHG=1373>All " XBD=2516 XHG=2410 YBD=1406 YHG=1373>these " XBD=2563 XHG=2542 YBD=1405 YHG=1375>5 " XBD=1546 XHG=1378 YBD=1459 YHG=1418>patients " XBD=1663 XHG=1565 YBD=1456 YHG=1417>died, " XBD=1758 XHG=1681 YBD=1450 YHG=1418>and " XBD=1815 XHG=1774 YBD=1450 YHG=1417>in " XBD=1902 XHG=1832 YBD=1450 YHG=1428>one " XBD=2004 XHG=1920 YBD=1450 YHG=1427>case " XBD=2137 XHG=2022 YBD=1450 YHG=1418>death " XBD=2230 XHG=2153 YBD=1450 YHG=1427>was " XBD=2321 XHG=2248 YBD=1450 YHG=1418>due " XBD=2379 XHG=2338 YBD=1450 YHG=1419>to " XBD=2563 XHG=2398 YBD=1451 YHG=1418>cerebral " XBD=1634 XHG=1379 YBD=1504 YHG=1462>haemorrhage " XBD=1801 XHG=1665 YBD=1495 YHG=1463>almost " XBD=2014 XHG=1831 YBD=1503 YHG=1462>certainly " XBD=2291 XHG=2043 YBD=1495 YHG=1462>attributable " XBD=2361 XHG=2320 YBD=1495 YHG=1465>to " XBD=2561 XHG=2390 YBD=1504 YHG=1463>heparin. " XBD=1499 XHG=1380 YBD=1540 YHG=1508>These " XBD=1734 XHG=1540 YBD=1540 YHG=1502>observers " XBD=1954 XHG=1774 YBD=1539 YHG=1507>conclude " XBD=2080 XHG=1991 YBD=1539 YHG=1502>that " XBD=2364 XHG=2121 YBD=1540 YHG=1508>intravenous " XBD=2561 XHG=2404 YBD=1548 YHG=1508>heparin " XBD=1515 XHG=1380 YBD=1585 YHG=1552>should " XBD=1605 XHG=1537 YBD=1583 YHG=1553>not " XBD=1675 XHG=1627 YBD=1584 YHG=1552>be " XBD=1802 XHG=1696 YBD=1588 YHG=1551>used, " XBD=1848 XHG=1825 YBD=1584 YHG=1561>a " XBD=1967 XHG=1870 YBD=1584 YHG=1552>view " XBD=2122 XHG=1987 YBD=1584 YHG=1552>shared " XBD=2197 XHG=2144 YBD=1593 YHG=1552>by " XBD=2319 XHG=2220 YBD=1584 YHG=1553>Katz " XBD=2419 XHG=2343 YBD=1584 YHG=1552>and " XBD=2565 XHG=2442 YBD=1589 YHG=1551>Elek |>" XBD=2565 XHG=2550 YBD=1570 YHG=1551>4 " XBD=1463 XHG=1378 YBD=1629 YHG=1597>who " XBD=1636 XHG=1484 YBD=1628 YHG=1597>blamed " XBD=1687 XHG=1656 YBD=1628 YHG=1597>it " XBD=1767 XHG=1707 YBD=1628 YHG=1596>for " XBD=1852 XHG=1786 YBD=1628 YHG=1596>the " XBD=2038 XHG=1873 YBD=1628 YHG=1596>cerebral " XBD=2310 XHG=2056 YBD=1638 YHG=1596>haemorrhage " XBD=2418 XHG=2330 YBD=1628 YHG=1596>that " XBD=2562 XHG=2438 YBD=1629 YHG=1596>devel- " XBD=1476 XHG=1379 YBD=1682 YHG=1642>oped " XBD=1542 XHG=1502 YBD=1672 YHG=1641>in " XBD=1582 XHG=1561 YBD=1671 YHG=1641>2 " XBD=1640 XHG=1600 YBD=1672 YHG=1641>of " XBD=1722 XHG=1657 YBD=1673 YHG=1641>the " XBD=1773 XHG=1750 YBD=1673 YHG=1642>4 " XBD=1901 XHG=1799 YBD=1672 YHG=1650>cases " XBD=2021 XHG=1928 YBD=1681 YHG=1640>they " XBD=2221 XHG=2046 YBD=1682 YHG=1641>reported " XBD=2324 XHG=2247 YBD=1673 YHG=1641>and " XBD=2459 XHG=2349 YBD=1674 YHG=1641>could " XBD=2566 XHG=2484 YBD=1673 YHG=1641>find " XBD=1428 XHG=1379 YBD=1718 YHG=1696>no " XBD=1641 XHG=1463 YBD=1718 YHG=1686>evidence " XBD=1758 XHG=1670 YBD=1717 YHG=1686>that " XBD=1810 XHG=1779 YBD=1717 YHG=1685>it " XBD=1898 XHG=1832 YBD=1717 YHG=1685>did " XBD=2016 XHG=1919 YBD=1727 YHG=1686>good " XBD=2077 XHG=2037 YBD=1717 YHG=1685>in " XBD=2174 XHG=2098 YBD=1726 YHG=1695>any " XBD=2235 XHG=2196 YBD=1717 YHG=1686>of " XBD=2381 XHG=2264 YBD=1718 YHG=1686>them. " XBD=2565 XHG=2442 YBD=1718 YHG=1686>Cooke " XBD=1459 XHG=1382 YBD=1762 YHG=1730>and " XBD=1613 XHG=1476 YBD=1772 YHG=1730>Taylor " XBD=1698 XHG=1629 YBD=1771 YHG=1740>say " XBD=1801 XHG=1713 YBD=1762 YHG=1730>that " XBD=2126 XHG=1817 YBD=1771 YHG=1730>long-continued " XBD=2435 XHG=2143 YBD=1771 YHG=1730>chemotherapy " XBD=2562 XHG=2452 YBD=1762 YHG=1730>offers " XBD=1405 XHG=1383 YBD=1807 YHG=1785>a " XBD=1565 XHG=1425 YBD=1807 YHG=1775>chance " XBD=1624 XHG=1584 YBD=1807 YHG=1774>of " XBD=1730 XHG=1643 YBD=1806 YHG=1784>cure " XBD=1787 XHG=1747 YBD=1807 YHG=1775>in " XBD=1829 XHG=1807 YBD=1807 YHG=1785>a " XBD=1921 XHG=1847 YBD=1807 YHG=1775>few " XBD=2116 XHG=1936 YBD=1816 YHG=1775>patients, " XBD=2207 XHG=2137 YBD=1807 YHG=1775>but " XBD=2318 XHG=2226 YBD=1816 YHG=1775>they " XBD=2458 XHG=2338 YBD=1807 YHG=1775>admit " XBD=2564 XHG=2476 YBD=1807 YHG=1775>that " XBD=1446 XHG=1379 YBD=1851 YHG=1820>the " XBD=1557 XHG=1470 YBD=1852 YHG=1821>vast " XBD=1762 XHG=1582 YBD=1860 YHG=1819>majority " XBD=1845 XHG=1782 YBD=1852 YHG=1829>are " XBD=1937 XHG=1869 YBD=1852 YHG=1821>not " XBD=2163 XHG=1963 YBD=1852 YHG=1819>benefited. " XBD=2313 XHG=2216 YBD=1860 YHG=1820>Only " XBD=2358 XHG=2343 YBD=1851 YHG=1821>1 " XBD=2433 XHG=2394 YBD=1852 YHG=1820>of " XBD=2561 XHG=2462 YBD=1852 YHG=1819>their " XBD=1430 XHG=1384 YBD=1896 YHG=1865>20 " XBD=1621 XHG=1452 YBD=1904 YHG=1865>patients " XBD=1720 XHG=1643 YBD=1896 YHG=1874>was " XBD=1823 XHG=1745 YBD=1896 YHG=1864>still " XBD=1944 XHG=1846 YBD=1896 YHG=1864>alive " XBD=1991 XHG=1968 YBD=1896 YHG=1874>a " XBD=2105 XHG=2014 YBD=1906 YHG=1874>year " XBD=2227 XHG=2128 YBD=1896 YHG=1865>after " XBD=2442 XHG=2251 YBD=1905 YHG=1857>discharge " XBD=2564 XHG=2465 YBD=1896 YHG=1864>from " XBD=1560 XHG=1382 YBD=1949 YHG=1909>hospital, " XBD=1627 XHG=1587 YBD=1941 YHG=1909>in " XBD=1751 XHG=1654 YBD=1950 YHG=1909>spite " XBD=1818 XHG=1779 YBD=1941 YHG=1910>of " XBD=1910 XHG=1844 YBD=1941 YHG=1909>the " XBD=2073 XHG=1936 YBD=1942 YHG=1910>almost " XBD=2365 XHG=2100 YBD=1942 YHG=1910>astronomical " XBD=2499 XHG=2392 YBD=1941 YHG=1910>doses " XBD=2566 XHG=2526 YBD=1941 YHG=1909>of " XBD=1688 XHG=1383 YBD=1994 YHG=1953>sulphonamides " XBD=1943 XHG=1711 YBD=1995 YHG=1954>given-700 " XBD=2000 XHG=1965 YBD=1996 YHG=1964>g. " XBD=2065 XHG=2026 YBD=1986 YHG=1955>of " XBD=2366 XHG=2086 YBD=1996 YHG=1953>sulphadiazine " XBD=2428 XHG=2388 YBD=1985 YHG=1954>in " XBD=2565 XHG=2451 YBD=1985 YHG=1963>seven " XBD=1536 XHG=1385 YBD=2030 YHG=1999>months " XBD=1587 XHG=1555 YBD=2030 YHG=1998>is " XBD=1656 XHG=1605 YBD=2030 YHG=2008>an " XBD=1859 XHG=1674 YBD=2041 YHG=1998>example. " XBD=2071 XHG=1912 YBD=2040 YHG=2000>Reports " XBD=2187 XHG=2089 YBD=2031 YHG=2000>have " XBD=2359 XHG=2206 YBD=2040 YHG=1999>already " XBD=2565 XHG=2378 YBD=2039 YHG=1999>appeared " XBD=1424 XHG=1384 YBD=2075 YHG=2044>in " XBD=1517 XHG=1450 YBD=2074 YHG=2043>the " XBD=1688 XHG=1546 YBD=2076 YHG=2042>United " XBD=1842 XHG=1716 YBD=2076 YHG=2044>States " XBD=1920 XHG=1871 YBD=2076 YHG=2054>on " XBD=2013 XHG=1946 YBD=2075 YHG=2044>the " XBD=2106 XHG=2040 YBD=2077 YHG=2053>use " XBD=2387 XHG=2134 YBD=2085 YHG=2043>of’ penicillin " XBD=2473 XHG=2414 YBD=2075 YHG=2043>for " XBD=2566 XHG=2500 YBD=2075 YHG=2043>the " XBD=1557 XHG=1382 YBD=2129 YHG=2097>purpose. " XBD=1686 XHG=1607 YBD=2120 YHG=2088>The " XBD=1843 XHG=1707 YBD=2120 YHG=2089>official verdict " XBD=2162 XHG=2023 YBD=2121 YHG=2088>5 there " XBD=2214 XHG=2182 YBD=2120 YHG=2089>is " XBD=2321 XHG=2235 YBD=2120 YHG=2089>that " XBD=2409 XHG=2342 YBD=2120 YHG=2088>the " XBD=2565 XHG=2429 YBD=2120 YHG=2087>results " XBD=1447 XHG=1385 YBD=2165 YHG=2143>are " XBD=1751 XHG=1470 YBD=2175 YHG=2133>disappointing " XBD=1848 XHG=1771 YBD=2165 YHG=2134>and " XBD=1933 XHG=1867 YBD=2165 YHG=2133>the " XBD=2051 XHG=1955 YBD=2175 YHG=2134>drug " XBD=2205 XHG=2069 YBD=2165 YHG=2133>should " XBD=2410 XHG=2223 YBD=2166 YHG=2133>therefore " XBD=2499 XHG=2430 YBD=2164 YHG=2134>not " XBD=2567 XHG=2520 YBD=2165 YHG=2132>be " XBD=1478 XHG=1384 YBD=2211 YHG=2178>used " XBD=1542 XHG=1502 YBD=2210 YHG=2178>in " XBD=1632 XHG=1566 YBD=2210 YHG=2177>the " XBD=1800 XHG=1659 YBD=2210 YHG=2178>disease " XBD=1924 XHG=1825 YBD=2210 YHG=2178>until " XBD=2068 XHG=1947 YBD=2219 YHG=2178>larger " XBD=2255 XHG=2092 YBD=2219 YHG=2178>supplies " XBD=2344 XHG=2280 YBD=2210 YHG=2188>are " XBD=2566 XHG=2369 YBD=2209 YHG=2177>available. " XBD=1463 XHG=1379 YBD=2255 YHG=2223>But " XBD=1521 XHG=1480 YBD=2254 YHG=2224>at " XBD=1603 XHG=1537 YBD=2254 YHG=2222>the " XBD=1885 XHG=1619 YBD=2263 YHG=2222>Presbyterian " XBD=2200 XHG=1903 YBD=2264 YHG=2218>Hospital,’New " XBD=2347 XHG=2216 YBD=2263 YHG=2223>YOJ;k,6 " XBD=2385 XHG=2363 YBD=2252 YHG=2223>2 " XBD=2567 XHG=2400 YBD=2263 YHG=2222>patients " XBD=1453 XHG=1385 YBD=2299 YHG=2268>out " XBD=1510 XHG=1471 YBD=2299 YHG=2268>of |>" XBD=1631 XHG=1525 YBD=2299 YHG=2267>the 5 " XBD=1759 XHG=1647 YBD=2309 YHG=2268>given " XBD=1964 XHG=1776 YBD=2308 YHG=2268>adequate " XBD=2118 XHG=1981 YBD=2309 YHG=2268>dosage " XBD=2228 XHG=2132 YBD=2299 YHG=2276>were " XBD=2470 XHG=2245 YBD=2307 YHG=2267>apparently " XBD=2570 XHG=2485 YBD=2299 YHG=2266>well " XBD=1552 XHG=1386 YBD=2343 YHG=2312>thirteen " XBD=1655 XHG=1578 YBD=2344 YHG=2312>and " XBD=1768 XHG=1680 YBD=2343 YHG=2312>nine " XBD=1947 XHG=1794 YBD=2343 YHG=2312>months " XBD=2072 XHG=1973 YBD=2344 YHG=2312>after " XBD=2284 XHG=2096 YBD=2352 YHG=2311>receiving " XBD=2466 XHG=2312 YBD=2348 YHG=2313>800,000 " XBD=2569 XHG=2493 YBD=2343 YHG=2312>and " XBD=1579 XHG=1391 YBD=2393 YHG=2357>1,400,000 " XBD=1715 XHG=1600 YBD=2393 YHG=2356>units, " XBD=1815 XHG=1738 YBD=2388 YHG=2357>and " XBD=1940 XHG=1834 YBD=2387 YHG=2356>these " XBD=2056 XHG=1961 YBD=2388 YHG=2366>were " XBD=2384 XHG=2077 YBD=2395 YHG=2355>non-haemolytic " XBD=2567 XHG=2407 YBD=2396 YHG=2357>strepto- " XBD=1511 XHG=1386 YBD=2432 YHG=2400>coccal " XBD=1638 XHG=1536 YBD=2432 YHG=2410>cases " XBD=1757 XHG=1664 YBD=2433 YHG=2400>with " XBD=1994 XHG=1782 YBD=2432 YHG=2400>rheumatic " XBD=2146 XHG=2018 YBD=2432 YHG=2400>hearts " XBD=2248 XHG=2172 YBD=2431 YHG=2400>and " XBD=2412 XHG=2274 YBD=2431 YHG=2400>emboli " XBD=2477 XHG=2437 YBD=2431 YHG=2400>in " XBD=2569 XHG=2503 YBD=2431 YHG=2400>the " XBD=1543 XHG=1384 YBD=2476 YHG=2444>femoral " XBD=1756 XHG=1591 YBD=2477 YHG=2446>arteries. |>" XBD=1976 XHG=1806 YBD=2476 YHG=2444>Another " XBD=2177 XHG=2023 YBD=2484 YHG=2444>report " XBD=2177 XHG=2165 YBD=2462 YHG=2444>7 " XBD=2431 XHG=2227 YBD=2476 YHG=2444>maintains " XBD=2568 XHG=2480 YBD=2476 YHG=2444>that " XBD=1575 XHG=1384 YBD=2529 YHG=2489>penicillin " XBD=1791 XHG=1592 YBD=2521 YHG=2489>combined " XBD=1899 XHG=1806 YBD=2520 YHG=2489>with " XBD=2072 XHG=1915 YBD=2529 YHG=2488>heparin " XBD=2180 XHG=2090 YBD=2529 YHG=2498>may " XBD=2244 XHG=2197 YBD=2521 YHG=2488>be " XBD=2301 XHG=2262 YBD=2520 YHG=2488>of " XBD=2440 XHG=2317 YBD=2521 YHG=2488>value. " XBD=2570 XHG=2491 YBD=2521 YHG=2489>The " XBD=1542 XHG=1384 YBD=2575 YHG=2534>heparin " XBD=1633 XHG=1556 YBD=2566 YHG=2544>was " XBD=1759 XHG=1648 YBD=2575 YHG=2534>given " XBD=2094 XHG=1775 YBD=2574 YHG=2533>subcutaneously " XBD=2148 XHG=2108 YBD=2565 YHG=2534>in " XBD=2271 XHG=2164 YBD=2565 YHG=2533>doses " XBD=2326 XHG=2287 YBD=2565 YHG=2533>of " XBD=2412 XHG=2344 YBD=2565 YHG=2534>300 " XBD=2503 XHG=2428 YBD=2574 YHG=2543>mg. " XBD=2570 XHG=2520 YBD=2566 YHG=2544>on " XBD=1569 XHG=1384 YBD=2611 YHG=2578>alternate " XBD=1689 XHG=1584 YBD=2619 YHG=2579>days, " XBD=1746 XHG=1704 YBD=2609 YHG=2588>or " XBD=2043 XHG=1757 YBD=2618 YHG=2578>intravenously " XBD=2094 XHG=2054 YBD=2609 YHG=2578>in " XBD=2215 XHG=2108 YBD=2609 YHG=2578>doses " XBD=2268 XHG=2228 YBD=2609 YHG=2578>of " XBD=2351 XHG=2280 YBD=2609 YHG=2578>200 " XBD=2438 XHG=2364 YBD=2620 YHG=2588>mg. " XBD=2568 XHG=2454 YBD=2620 YHG=2578>daily, " XBD=1609 XHG=1384 YBD=2664 YHG=2623>apparently " XBD=1790 XHG=1627 YBD=2655 YHG=2623>without |>" XBD=1988 XHG=1808 YBD=2654 YHG=2621>ill-effect. " XBD=2117 XHG=2038 YBD=2653 YHG=2622>The " XBD=2234 XHG=2135 YBD=2653 YHG=2622>total " XBD=2389 XHG=2252 YBD=2664 YHG=2622>dosage " XBD=2448 XHG=2409 YBD=2654 YHG=2623>of " XBD=2569 XHG=2465 YBD=2663 YHG=2624>peni- " XBD=1487 XHG=1386 YBD=2698 YHG=2667>cillin " XBD=1643 XHG=1501 YBD=2708 YHG=2667>ranged " XBD=1755 XHG=1657 YBD=2698 YHG=2667>from " XBD=1927 XHG=1774 YBD=2703 YHG=2668>870,000 " XBD=1984 XHG=1942 YBD=2698 YHG=2667>to " XBD=2130 XHG=1999 YBD=2706 YHG=2666>nearly " XBD=2339 XHG=2147 YBD=2703 YHG=2667>8,000,000 " XBD=2468 XHG=2353 YBD=2699 YHG=2668>units. " XBD=2570 XHG=2521 YBD=2700 YHG=2668>Of " XBD=1451 XHG=1386 YBD=2742 YHG=2711>the " XBD=1496 XHG=1476 YBD=2742 YHG=2713>7 " XBD=1686 XHG=1519 YBD=2751 YHG=2712>patients " XBD=1869 XHG=1708 YBD=2747 YHG=2710>treated, " XBD=1932 XHG=1892 YBD=2741 YHG=2710>in " XBD=1980 XHG=1958 YBD=2742 YHG=2713>5 " XBD=2066 XHG=2000 YBD=2741 YHG=2710>the " XBD=2279 XHG=2091 YBD=2752 YHG=2710>organism " XBD=2376 XHG=2299 YBD=2743 YHG=2720>was " XBD=2424 XHG=2401 YBD=2742 YHG=2721>a " XBD=2566 XHG=2450 YBD=2752 YHG=2712>Strep. " XBD=1564 XHG=1386 YBD=2791 YHG=2756>viridans, " XBD=1632 XHG=1592 YBD=2786 YHG=2755>in " XBD=1680 XHG=1665 YBD=2785 YHG=2756>1 " XBD=1734 XHG=1711 YBD=2785 YHG=2763>a " XBD=1977 XHG=1760 YBD=2794 YHG=2754>haemolytic " XBD=2297 XHG=2006 YBD=2794 YHG=2755>streptococcus, " XBD=2402 XHG=2326 YBD=2786 YHG=2755>and " XBD=2469 XHG=2429 YBD=2786 YHG=2755>in " XBD=2517 XHG=2501 YBD=2787 YHG=2757>1 " XBD=2571 XHG=2548 YBD=2787 YHG=2765>a " XBD=1683 XHG=1385 YBD=2840 YHG=2807>pneumococcus " XBD=1790 XHG=1697 YBD=2838 YHG=2799>type " XBD=1864 XHG=1806 YBD=2830 YHG=2798>27. " XBD=1961 XHG=1915 YBD=2830 YHG=2798>In " XBD=2037 XHG=1976 YBD=2835 YHG=2798>all, " XBD=2294 XHG=2053 YBD=2831 YHG=2798>sterilisation " XBD=2348 XHG=2309 YBD=2830 YHG=2799>of " XBD=2427 XHG=2361 YBD=2831 YHG=2799>the " XBD=2570 XHG=2441 YBD=2832 YHG=2800>blood- " XBD=1526 XHG=1386 YBD=2875 YHG=2845>stream " XBD=1614 XHG=1537 YBD=2875 YHG=2853>was " XBD=1808 XHG=1628 YBD=2874 YHG=2843>obtained " XBD=1913 XHG=1818 YBD=2875 YHG=2843>with " XBD=2215 XHG=1926 YBD=2883 YHG=2843>corresponding " XBD=2373 XHG=2227 YBD=2875 YHG=2843>clinical " XBD=2570 XHG=2384 YBD=2885 YHG=2844>improve- " XBD=1503 XHG=1386 YBD=2919 YHG=2889>ment. " XBD=1631 XHG=1554 YBD=2919 YHG=2887>But " XBD=1753 XHG=1656 YBD=2918 YHG=2896>none " XBD=1817 XHG=1778 YBD=2918 YHG=2887>of " XBD=1945 XHG=1839 YBD=2919 YHG=2887>them " XBD=2046 XHG=1968 YBD=2919 YHG=2887>had " XBD=2164 XHG=2069 YBD=2919 YHG=2887>been " XBD=2360 XHG=2186 YBD=2920 YHG=2887>followed " XBD=2441 XHG=2382 YBD=2921 YHG=2889>for " XBD=2568 XHG=2465 YBD=2920 YHG=2898>more " XBD=1482 XHG=1385 YBD=2963 YHG=2932>than " XBD=1521 XHG=1499 YBD=2963 YHG=2941>a " XBD=1612 XHG=1539 YBD=2964 YHG=2931>few " XBD=1782 XHG=1629 YBD=2963 YHG=2931>months " XBD=1898 XHG=1800 YBD=2963 YHG=2931>after " XBD=2109 XHG=1917 YBD=2971 YHG=2931>discharge " XBD=2225 XHG=2126 YBD=2963 YHG=2931>from " XBD=2419 XHG=2241 YBD=2973 YHG=2931>hospital, " XBD=2514 XHG=2438 YBD=2964 YHG=2934>and " XBD=2571 XHG=2531 YBD=2963 YHG=2933>in " XBD=1529 XHG=1386 YBD=3008 YHG=2975>several " XBD=1712 XHG=1551 YBD=3007 YHG=2976>massive " XBD=2022 XHG=1734 YBD=3016 YHG=2975>sulphonamide " XBD=2205 XHG=2043 YBD=3016 YHG=2976>therapy " XBD=2302 XHG=2225 YBD=3008 YHG=2985>was " XBD=2422 XHG=2324 YBD=3009 YHG=2977>tried " XBD=2571 XHG=2443 YBD=3007 YHG=2977>before " XBD=1451 XHG=1385 YBD=3052 YHG=3021>the " XBD=1677 XHG=1475 YBD=3060 YHG=3020>penicillin. " XBD=1782 XHG=1728 YBD=3051 YHG=3020>To " XBD=1926 XHG=1807 YBD=3051 YHG=3028>assess " XBD=2007 XHG=1941 YBD=3051 YHG=3020>the " XBD=2259 XHG=2024 YBD=3060 YHG=3019>significance " XBD=2315 XHG=2276 YBD=3053 YHG=3021>of " XBD=2423 XHG=2330 YBD=3053 YHG=3021>such " XBD=2572 XHG=2448 YBD=3052 YHG=3020>obser- " XBD=1536 XHG=1385 YBD=3097 YHG=3065>vations " XBD=1597 XHG=1567 YBD=3096 YHG=3064>is " XBD=1818 XHG=1629 YBD=3105 YHG=3064>well-nigh " XBD=2077 XHG=1849 YBD=3104 YHG=3064>impossible. " XBD=2228 XHG=2130 YBD=3097 YHG=3065>Here " XBD=2391 XHG=2258 YBD=3098 YHG=3065>within " XBD=2438 XHG=2416 YBD=3095 YHG=3074>a " XBD=2571 XHG=2464 YBD=3096 YHG=3064>short 1. Kelson, S. R. and White, P. D. J. Amer. med. Ass. 1939, 113, 1700; Friedman, M., Hamburger, W. W. and Katz, L. N. Ibid, 1939, 113, 1702. 2. Fletcher, C. M. Lancet, 1940, ii, 512; Petch, C. P. Ibid, 1940, ii, 637. 3. Cooke, W. T. and Taylor, B. Brit. Heart J. 1943, 5, 229. 4. Katz, L. N. and Elek, S. R. J. Amer. med. Ass. 1944, 124, 149. 5. Keefer, C. S., Blake, F. G., Marshall, B. K. jun., Lockwood, J. S. and Wood, W. B. jun., Ibid, 1943, 122, 1217. 6. Dawson, M. H. and Hobby, G. L. Ibid, 1944, 124, 611. 7. Loewe, L., Rosenblatt, P., Greene, H. J. and Russell, M. Ibid, 1944, 124, 144.
Transcript
Page 1: TREATMENT OF BACTERIAL ENDOCARDITIS

117

" XBD=207 XHG=133 YBD=212 YHG=180>and " XBD=313 XHG=224 YBD=212 YHG=180>Glen " XBD=341 XHG=328 YBD=199 YHG=180>6 " XBD=464 XHG=355 YBD=212 YHG=180>when " XBD=572 XHG=479 YBD=222 YHG=181>they " XBD=871 XHG=589 YBD=213 YHG=181>demonstrated " XBD=973 XHG=887 YBD=212 YHG=181>that " XBD=1166 XHG=989 YBD=221 YHG=181>ordinary " XBD=1302 XHG=1184 YBD=217 YHG=181>doses," XBD=226 XHG=135 YBD=258 YHG=225>such " XBD=283 XHG=242 YBD=256 YHG=234>as " XBD=422 XHG=303 YBD=265 YHG=225>might " XBD=489 XHG=442 YBD=256 YHG=225>be " XBD=600 XHG=508 YBD=258 YHG=225>used " XBD=968 XHG=619 YBD=265 YHG=224>prophylactically, " XBD=1065 XHG=988 YBD=256 YHG=225>had " XBD=1134 XHG=1086 YBD=255 YHG=234>an " XBD=1304 XHG=1153 YBD=265 YHG=224>insigni-" XBD=285 XHG=135 YBD=310 YHG=270>ficantly " XBD=452 XHG=299 YBD=300 YHG=269>adverse " XBD=576 XHG=467 YBD=301 YHG=269>effect " XBD=641 XHG=592 YBD=300 YHG=279>on " XBD=980 XHG=654 YBD=309 YHG=269>intelligence-test " XBD=1127 XHG=995 YBD=300 YHG=277>scores. " XBD=1224 XHG=1179 YBD=299 YHG=269>In " XBD=1305 XHG=1238 YBD=299 YHG=268>the" XBD=233 XHG=134 YBD=355 YHG=315>early " XBD=367 XHG=246 YBD=354 YHG=316>stages " XBD=421 XHG=383 YBD=344 YHG=313>of " XBD=501 XHG=434 YBD=344 YHG=313>the " XBD=736 XHG=516 YBD=353 YHG=314>Normandy " XBD=960 XHG=752 YBD=353 YHG=313>campaign, " XBD=1128 XHG=978 YBD=344 YHG=311>Colonel " XBD=1305 XHG=1142 YBD=353 YHG=313>Thomp-" XBD=199 XHG=133 YBD=391 YHG=369>son " XBD=259 XHG=221 YBD=389 YHG=358>of " XBD=344 XHG=279 YBD=389 YHG=359>the " XBD=427 XHG=367 YBD=389 YHG=357>US " XBD=570 XHG=450 YBD=397 YHG=357>Army " XBD=673 XHG=591 YBD=388 YHG=357>told " XBD=885 XHG=699 YBD=396 YHG=358>reporters " XBD=994 XHG=907 YBD=387 YHG=357>that " XBD=1105 XHG=1019 YBD=397 YHG=356>75% " XBD=1167 XHG=1129 YBD=388 YHG=357>of " XBD=1308 XHG=1197 YBD=388 YHG=358>acute" XBD=373 XHG=104 YBD=434 YHG=396>breakdowns " XBD=430 XHG=391 YBD=432 YHG=401>in " XBD=513 XHG=447 YBD=432 YHG=401>the " XBD=632 XHG=529 YBD=432 YHG=401>front " XBD=723 XHG=650 YBD=432 YHG=402>line " XBD=803 XHG=742 YBD=431 YHG=410>are " XBD=933 XHG=822 YBD=441 YHG=400>being " XBD=1016 XHG=950 YBD=440 YHG=401>got " XBD=1131 XHG=1033 YBD=431 YHG=400>back " XBD=1190 XHG=1148 YBD=431 YHG=402>to " XBD=1306 XHG=1210 YBD=440 YHG=400>duty" XBD=184 XHG=136 YBD=487 YHG=448>by " XBD=303 XHG=201 YBD=477 YHG=447>these " XBD=506 XHG=321 YBD=476 YHG=445>methods. " XBD=645 XHG=556 YBD=475 YHG=444>This " XBD=778 XHG=662 YBD=484 YHG=444>figure " XBD=983 XHG=796 YBD=475 YHG=445>contrasts " XBD=1092 XHG=999 YBD=475 YHG=443>with " XBD=1175 XHG=1110 YBD=474 YHG=444>the " XBD=1306 XHG=1194 YBD=474 YHG=444>much" XBD=241 XHG=136 YBD=521 YHG=491>lower " XBD=333 XHG=265 YBD=520 YHG=499>one " XBD=396 XHG=357 YBD=519 YHG=489>of " XBD=484 XHG=418 YBD=519 YHG=489>the " XBD=683 XHG=507 YBD=519 YHG=488>numbers " XBD=886 XHG=707 YBD=519 YHG=488>returned " XBD=949 XHG=907 YBD=518 YHG=489>to " XBD=1071 XHG=974 YBD=527 YHG=486>duty " XBD=1192 XHG=1093 YBD=518 YHG=487>from " XBD=1306 XHG=1214 YBD=519 YHG=487>base" XBD=323 XHG=133 YBD=573 YHG=533>hospitals, " XBD=420 XHG=345 YBD=563 YHG=532>and " XBD=648 XHG=439 YBD=572 YHG=534>represents " XBD=690 XHG=669 YBD=562 YHG=541>a " XBD=922 XHG=712 YBD=572 YHG=531>significant " XBD=1112 XHG=943 YBD=562 YHG=531>advance " XBD=1171 XHG=1132 YBD=562 YHG=531>in " XBD=1306 XHG=1191 YBD=562 YHG=532>treat-" XBD=247 XHG=136 YBD=609 YHG=578>ment. " XBD=414 XHG=297 YBD=607 YHG=576>These " XBD=565 XHG=425 YBD=607 YHG=576>lessons " XBD=698 XHG=579 YBD=616 YHG=575>might " XBD=758 XHG=711 YBD=606 YHG=576>be " XBD=922 XHG=771 YBD=615 YHG=575>applied " XBD=1068 XHG=934 YBD=615 YHG=575>during " XBD=1144 XHG=1079 YBD=606 YHG=575>the " XBD=1307 XHG=1155 YBD=615 YHG=575>present" XBD=347 XHG=137 YBD=661 YHG=622>long-range " XBD=499 XHG=367 YBD=651 YHG=619>attack " XBD=567 XHG=519 YBD=651 YHG=630>on " XBD=738 XHG=588 YBD=650 YHG=620>civilian " XBD=820 XHG=756 YBD=650 YHG=619>life " XBD=916 XHG=840 YBD=650 YHG=619>and " XBD=1076 XHG=937 YBD=650 YHG=619>morale " XBD=1148 XHG=1096 YBD=659 YHG=619>by " XBD=1308 XHG=1166 YBD=659 YHG=628>power-" XBD=278 XHG=137 YBD=697 YHG=665>bombs. " XBD=374 XHG=328 YBD=695 YHG=664>In " XBD=421 XHG=399 YBD=694 YHG=673>a " XBD=562 XHG=448 YBD=695 YHG=664>letter " XBD=651 XHG=586 YBD=694 YHG=663>Dr. " XBD=840 XHG=680 YBD=695 YHG=655>Stewart " XBD=951 XHG=864 YBD=694 YHG=663>tells " XBD=1060 XHG=974 YBD=695 YHG=663>how " XBD=1123 XHG=1084 YBD=695 YHG=664>in " XBD=1312 XHG=1146 YBD=694 YHG=662>bombed" XBD=302 XHG=136 YBD=741 YHG=708>civilians " XBD=395 XHG=328 YBD=739 YHG=709>the " XBD=578 XHG=417 YBD=739 YHG=717>nervous " XBD=747 XHG=605 YBD=748 YHG=709>system " XBD=846 XHG=776 YBD=738 YHG=717>can " XBD=915 XHG=868 YBD=739 YHG=708>be " XBD=1139 XHG=942 YBD=748 YHG=707>protected " XBD=1308 XHG=1161 YBD=748 YHG=707>against" XBD=197 XHG=135 YBD=785 YHG=754>the " XBD=487 XHG=214 YBD=784 YHG=752>accumulation " XBD=550 XHG=512 YBD=783 YHG=752>of " XBD=731 XHG=573 YBD=792 YHG=752>phobias " XBD=832 XHG=757 YBD=784 YHG=753>and " XBD=1063 XHG=856 YBD=793 YHG=749>increasing " XBD=1233 XHG=1085 YBD=783 YHG=752>tension " XBD=1310 XHG=1257 YBD=792 YHG=752>by" XBD=299 XHG=136 YBD=836 YHG=797>securing " XBD=452 XHG=307 YBD=836 YHG=797>regular " XBD=538 XHG=462 YBD=827 YHG=797>and " XBD=738 XHG=552 YBD=835 YHG=796>adequate " XBD=850 XHG=752 YBD=837 YHG=797>sleep " XBD=954 XHG=878 YBD=827 YHG=797>and " XBD=1144 XHG=965 YBD=839 YHG=796>reducing " XBD=1312 XHG=1155 YBD=836 YHG=797>anxiety" XBD=345 XHG=137 YBD=872 YHG=840>tendencies " XBD=493 XHG=359 YBD=880 YHG=840>during " XBD=654 XHG=504 YBD=880 YHG=840>waking " XBD=790 XHG=664 YBD=872 YHG=840>hours. " XBD=954 XHG=841 YBD=871 YHG=840>From " XBD=1138 XHG=965 YBD=872 YHG=840>America " XBD=1276 XHG=1151 YBD=872 YHG=849>comes " XBD=1312 XHG=1289 YBD=871 YHG=849>a" XBD=284 XHG=137 YBD=925 YHG=883>report 7 on " XBD=592 XHG=362 YBD=925 YHG=884>ergotamine " XBD=767 XHG=605 YBD=916 YHG=885>tartrate " XBD=821 XHG=781 YBD=915 YHG=885>in " XBD=901 XHG=835 YBD=916 YHG=885>the " XBD=1121 XHG=915 YBD=916 YHG=885>treatment " XBD=1176 XHG=1137 YBD=916 YHG=884>of " XBD=1313 XHG=1190 YBD=916 YHG=884>battle" XBD=329 XHG=137 YBD=960 YHG=928>casualties " XBD=402 XHG=361 YBD=959 YHG=929>at " XBD=509 XHG=434 YBD=960 YHG=938>sea. " XBD=648 XHG=559 YBD=960 YHG=928>This " XBD=776 XHG=681 YBD=970 YHG=929>drug " XBD=1026 XHG=806 YBD=961 YHG=928>neutralises " XBD=1313 XHG=1058 YBD=970 YHG=929>sympathetic" XBD=384 XHG=140 YBD=1013 YHG=971>overactivity " XBD=485 XHG=408 YBD=1004 YHG=973>and " XBD=675 XHG=508 YBD=1014 YHG=973>patients " XBD=876 XHG=699 YBD=1013 YHG=974>reported " XBD=986 XHG=900 YBD=1005 YHG=973>that " XBD=1044 XHG=1012 YBD=1005 YHG=974>it " XBD=1181 XHG=1070 YBD=1005 YHG=974>made " XBD=1322 XHG=1206 YBD=1006 YHG=974>them." XBD=207 XHG=137 YBD=1049 YHG=1017>feel " XBD=376 XHG=229 YBD=1054 YHG=1017>calmer, " XBD=573 XHG=403 YBD=1059 YHG=1019>stronger " XBD=674 XHG=597 YBD=1049 YHG=1017>and " XBD=801 XHG=698 YBD=1049 YHG=1027>more " XBD=867 XHG=826 YBD=1049 YHG=1019>at " XBD=988 XHG=893 YBD=1055 YHG=1027>ease, " XBD=1092 XHG=1016 YBD=1050 YHG=1018>and " XBD=1314 XHG=1116 YBD=1059 YHG=1018>improved" XBD=232 XHG=136 YBD=1093 YHG=1061>their " XBD=464 XHG=266 YBD=1102 YHG=1062>appetites. " XBD=566 XHG=514 YBD=1094 YHG=1061>As " XBD=694 XHG=601 YBD=1094 YHG=1062>with " XBD=965 XHG=728 YBD=1094 YHG=1062>barbiturate " XBD=1184 XHG=1000 YBD=1100 YHG=1063>sedation, " XBD=1314 XHG=1219 YBD=1103 YHG=1072>poor" XBD=268 XHG=139 YBD=1137 YHG=1106>results " XBD=393 XHG=298 YBD=1138 YHG=1115>were " XBD=614 XHG=424 YBD=1138 YHG=1106>obtained- " XBD=673 XHG=633 YBD=1137 YHG=1106>in " XBD=769 XHG=702 YBD=1138 YHG=1107>the " XBD=950 XHG=799 YBD=1139 YHG=1107>chronic " XBD=1149 XHG=980 YBD=1139 YHG=1108>neurotic " XBD=1312 XHG=1181 YBD=1139 YHG=1108>states." XBD=188 XHG=140 YBD=1182 YHG=1150>As " XBD=229 XHG=208 YBD=1181 YHG=1160>a " XBD=326 XHG=246 YBD=1181 YHG=1150>first " XBD=447 XHG=347 YBD=1188 YHG=1150>dose, " XBD=490 XHG=471 YBD=1182 YHG=1152>3 " XBD=585 XHG=511 YBD=1192 YHG=1159>mg. " XBD=837 XHG=606 YBD=1192 YHG=1151>ergotamine " XBD=1018 XHG=855 YBD=1184 YHG=1153>tartrate " XBD=1113 XHG=1035 YBD=1184 YHG=1161>was " XBD=1243 XHG=1132 YBD=1193 YHG=1151>given " XBD=1315 XHG=1262 YBD=1192 YHG=1152>by" XBD=280 XHG=141 YBD=1231 YHG=1195>mouth, " XBD=375 XHG=299 YBD=1227 YHG=1195>and " XBD=485 XHG=392 YBD=1227 YHG=1195>then " XBD=526 XHG=504 YBD=1226 YHG=1195>2 " XBD=621 XHG=546 YBD=1237 YHG=1205>mg. " XBD=717 XHG=640 YBD=1228 YHG=1205>was " XBD=848 XHG=736 YBD=1237 YHG=1196>given " XBD=980 XHG=866 YBD=1236 YHG=1206>every " XBD=1104 XHG=998 YBD=1227 YHG=1196>three " XBD=1236 XHG=1121 YBD=1228 YHG=1197>hours " XBD=1315 XHG=1255 YBD=1227 YHG=1196>for" XBD=202 XHG=139 YBD=1270 YHG=1240>ten " XBD=345 XHG=241 YBD=1280 YHG=1239>days. " XBD=433 XHG=396 YBD=1271 YHG=1240>It " XBD=565 XHG=475 YBD=1280 YHG=1249>may " XBD=720 XHG=602 YBD=1281 YHG=1250>prove " XBD=935 XHG=760 YBD=1272 YHG=1240>valuable " XBD=1015 XHG=975 YBD=1273 YHG=1241>in " XBD=1313 XHG=1054 YBD=1281 YHG=1240>prophylaxis." XBD=237 XHG=123 YBD=1315 YHG=1283>Both " XBD=479 XHG=250 YBD=1324 YHG=1284>ergotamine " XBD=568 XHG=492 YBD=1317 YHG=1285>and " XBD=646 XHG=580 YBD=1316 YHG=1286>the " XBD=913 XHG=660 YBD=1317 YHG=1285>barbiturates " XBD=1061 XHG=926 YBD=1317 YHG=1285>reduce " XBD=1140 XHG=1074 YBD=1316 YHG=1285>the " XBD=1314 XHG=1153 YBD=1317 YHG=1286>somatic" XBD=476 XHG=138 YBD=1368 YHG=1328>accompaniments " XBD=535 XHG=496 YBD=1361 YHG=1329>of " XBD=645 XHG=553 YBD=1366 YHG=1330>fear, " XBD=745 XHG=668 YBD=1361 YHG=1329>and " XBD=928 XHG=764 YBD=1361 YHG=1330>without " XBD=1056 XHG=949 YBD=1361 YHG=1330>these " XBD=1316 XHG=1077 YBD=1369 YHG=1329>accompani-" XBD=257 XHG=139 YBD=1405 YHG=1373>ments " XBD=345 XHG=280 YBD=1405 YHG=1373>the " XBD=533 XHG=365 YBD=1405 YHG=1374>emotion " XBD=658 XHG=555 YBD=1405 YHG=1374>itself " XBD=711 XHG=679 YBD=1406 YHG=1374>is " XBD=872 XHG=727 YBD=1406 YHG=1373>robbed " XBD=935 XHG=896 YBD=1406 YHG=1375>of " XBD=1007 XHG=956 YBD=1405 YHG=1374>its " XBD=1163 XHG=1024 YBD=1415 YHG=1383>power.

THIOCYANATES IN HYPERTENSION

" XBD=236 XHG=185 YBD=1548 YHG=1517>As " XBD=350 XHG=256 YBD=1548 YHG=1516>with " XBD=487 XHG=370 YBD=1558 YHG=1527>many " XBD=616 XHG=508 YBD=1548 YHG=1517>other " XBD=853 XHG=637 YBD=1549 YHG=1517>vaunted &dquo; " XBD=1010 XHG=869 YBD=1548 YHG=1518>cures &dquo; " XBD=1092 XHG=1032 YBD=1548 YHG=1517>for " XBD=1314 XHG=1112 YBD=1557 YHG=1516>hyperten-" XBD=230 XHG=140 YBD=1598 YHG=1562>sion, " XBD=286 XHG=255 YBD=1592 YHG=1561>it " XBD=341 XHG=310 YBD=1593 YHG=1562>is " XBD=525 XHG=368 YBD=1594 YHG=1561>difficult " XBD=648 XHG=547 YBD=1593 YHG=1561>from " XBD=738 XHG=672 YBD=1593 YHG=1562>the " XBD=941 XHG=762 YBD=1593 YHG=1561>evidence " XBD=1007 XHG=965 YBD=1593 YHG=1563>to " XBD=1137 XHG=1034 YBD=1593 YHG=1561>draw " XBD=1316 XHG=1163 YBD=1593 YHG=1561>definite" XBD=366 XHG=141 YBD=1638 YHG=1606>conclusions " XBD=445 XHG=396 YBD=1637 YHG=1616>on " XBD=539 XHG=473 YBD=1638 YHG=1605>the " XBD=680 XHG=568 YBD=1637 YHG=1606>value " XBD=749 XHG=710 YBD=1637 YHG=1606>of " XBD=842 XHG=775 YBD=1637 YHG=1605>the " XBD=1135 XHG=870 YBD=1646 YHG=1606>thiocyanates " XBD=1222 XHG=1165 YBD=1646 YHG=1608>(or " XBD=1317 XHG=1249 YBD=1637 YHG=1605>the" XBD=461 XHG=142 YBD=1691 YHG=1650>sulphocyanides, " XBD=526 XHG=485 YBD=1682 YHG=1660>as " XBD=601 XHG=545 YBD=1682 YHG=1660>we " XBD=715 XHG=621 YBD=1682 YHG=1650>used " XBD=777 XHG=735 YBD=1682 YHG=1651>to " XBD=871 XHG=799 YBD=1681 YHG=1650>call " XBD=1025 XHG=891 YBD=1690 YHG=1650>them). " XBD=1123 XHG=1076 YBD=1681 YHG=1650>In " XBD=1318 XHG=1143 YBD=1682 YHG=1649>America" XBD=289 XHG=143 YBD=1735 YHG=1695>opinion " XBD=331 XHG=302 YBD=1726 YHG=1695>is " XBD=513 XHG=347 YBD=1726 YHG=1695>divided. " XBD=636 XHG=558 YBD=1727 YHG=1694>One " XBD=686 XHG=648 YBD=1726 YHG=1694>of " XBD=762 XHG=696 YBD=1726 YHG=1695>the " XBD=844 XHG=771 YBD=1727 YHG=1695>few " XBD=996 XHG=854 YBD=1726 YHG=1695>British " XBD=1319 XHG=1006 YBD=1735 YHG=1694>investigations " XBD=1319 XHG=1305 YBD=1714 YHG=1695>8" XBD=303 XHG=141 YBD=1780 YHG=1740>suggests " XBD=417 XHG=328 YBD=1771 YHG=1739>that " XBD=511 XHG=444 YBD=1771 YHG=1739>the " XBD=652 XHG=539 YBD=1780 YHG=1740>drugs " XBD=770 XHG=680 YBD=1779 YHG=1748>may " XBD=973 XHG=798 YBD=1771 YHG=1739>alleviate " XBD=1213 XHG=1000 YBD=1780 YHG=1740>symptoms " XBD=1319 XHG=1242 YBD=1770 YHG=1739>and" XBD=301 XHG=142 YBD=1824 YHG=1784>produce " XBD=372 XHG=331 YBD=1815 YHG=1786>at " XBD=499 XHG=402 YBD=1816 YHG=1784>least " XBD=554 XHG=531 YBD=1815 YHG=1793>a " XBD=804 XHG=584 YBD=1824 YHG=1785>temporary " XBD=902 XHG=833 YBD=1815 YHG=1783>fall " XBD=971 XHG=931 YBD=1815 YHG=1784>in " XBD=1315 XHG=1001 YBD=1824 YHG=1783>blood-pressure." XBD=384 XHG=143 YBD=1869 YHG=1828>Twenty-five " XBD=632 XHG=417 YBD=1860 YHG=1828>unselected " XBD=777 XHG=663 YBD=1865 YHG=1838>cases, " XBD=848 XHG=808 YBD=1859 YHG=1828>in " XBD=930 XHG=880 YBD=1859 YHG=1828>all " XBD=1000 XHG=961 YBD=1859 YHG=1828>of " XBD=1151 XHG=1028 YBD=1860 YHG=1828>which " XBD=1317 XHG=1181 YBD=1868 YHG=1828>hyper-" XBD=285 XHG=143 YBD=1905 YHG=1873>tension " XBD=399 XHG=320 YBD=1905 YHG=1883>was " XBD=574 XHG=435 YBD=1904 YHG=1873>known " XBD=652 XHG=609 YBD=1904 YHG=1875>to " XBD=786 XHG=685 YBD=1904 YHG=1873>have " XBD=912 XHG=818 YBD=1904 YHG=1873>been " XBD=1092 XHG=941 YBD=1913 YHG=1874>present " XBD=1188 XHG=1128 YBD=1904 YHG=1873>for " XBD=1317 XHG=1228 YBD=1904 YHG=1873>1-12" XBD=257 XHG=144 YBD=1958 YHG=1927>years, " XBD=381 XHG=286 YBD=1949 YHG=1927>were " XBD=676 XHG=409 YBD=1958 YHG=1917>investigated, " XBD=784 XHG=708 YBD=1949 YHG=1917>and " XBD=912 XHG=815 YBD=1948 YHG=1917>after " XBD=991 XHG=942 YBD=1949 YHG=1927>an " XBD=1143 XHG=1019 YBD=1949 YHG=1917>initial " XBD=1320 XHG=1171 YBD=1949 YHG=1917>control" XBD=269 XHG=144 YBD=2003 YHG=1962>period " XBD=327 XHG=289 YBD=1993 YHG=1962>of " XBD=376 XHG=353 YBD=1993 YHG=1971>a " XBD=505 XHG=400 YBD=1994 YHG=1962>week " XBD=741 XHG=529 YBD=2002 YHG=1962>potassium " XBD=1012 XHG=765 YBD=2002 YHG=1962>thiocyanate " XBD=1114 XHG=1036 YBD=1994 YHG=1971>was " XBD=1251 XHG=1139 YBD=2003 YHG=1961>given " XBD=1316 XHG=1276 YBD=1993 YHG=1962>in" XBD=246 XHG=147 YBD=2039 YHG=2007>doses " XBD=298 XHG=259 YBD=2038 YHG=2006>of " XBD=365 XHG=309 YBD=2038 YHG=2008>O’l g. " XBD=532 XHG=426 YBD=2038 YHG=2007>three " XBD=654 XHG=543 YBD=2038 YHG=2006>times " XBD=689 XHG=668 YBD=2037 YHG=2016>a " XBD=790 XHG=703 YBD=2046 YHG=2006>day. " XBD=892 XHG=840 YBD=2037 YHG=2006>At " XBD=970 XHG=904 YBD=2037 YHG=2006>the " XBD=1056 XHG=982 YBD=2038 YHG=2006>end " XBD=1108 XHG=1069 YBD=2038 YHG=2006>of " XBD=1142 XHG=1120 YBD=2038 YHG=2016>a " XBD=1257 XHG=1152 YBD=2038 YHG=2006>week " XBD=1319 XHG=1270 YBD=2038 YHG=2016>on" XBD=215 XHG=144 YBD=2083 YHG=2051>this " XBD=368 XHG=231 YBD=2092 YHG=2051>dosage " XBD=449 XHG=382 YBD=2082 YHG=2051>the " XBD=585 XHG=462 YBD=2082 YHG=2060>serum " XBD=844 XHG=598 YBD=2091 YHG=2051>thiocyanate " XBD=934 XHG=856 YBD=2082 YHG=2059>was " XBD=1160 XHG=947 YBD=2088 YHG=2050>estimated, " XBD=1253 XHG=1176 YBD=2083 YHG=2051>and " XBD=1318 XHG=1269 YBD=2083 YHG=2061>on" XBD=206 XHG=145 YBD=2128 YHG=2095>the " XBD=324 XHG=225 YBD=2127 YHG=2095>basis " XBD=387 XHG=348 YBD=2127 YHG=2096>of " XBD=475 XHG=408 YBD=2127 YHG=2095>the " XBD=660 XHG=497 YBD=2136 YHG=2095>findings " XBD=749 XHG=681 YBD=2127 YHG=2095>the " XBD=939 XHG=771 YBD=2136 YHG=2095>patients " XBD=1073 XHG=961 YBD=2126 YHG=2095>could " XBD=1141 XHG=1095 YBD=2127 YHG=2095>be " XBD=1320 XHG=1165 YBD=2127 YHG=2095>divided" XBD=221 XHG=145 YBD=2172 YHG=2140>into " XBD=342 XHG=237 YBD=2172 YHG=2140>three " XBD=462 XHG=360 YBD=2171 YHG=2140>main " XBD=779 XHG=481 YBD=2181 YHG=2140>groups-those " XBD=835 XHG=795 YBD=2170 YHG=2139>in " XBD=979 XHG=852 YBD=2171 YHG=2139>whom " XBD=1062 XHG=996 YBD=2171 YHG=2139>the " XBD=1204 XHG=1080 YBD=2174 YHG=2149>serum " XBD=1319 XHG=1221 YBD=2171 YHG=2136>thio-" XBD=301 XHG=146 YBD=2225 YHG=2186>cyanate " XBD=391 XHG=314 YBD=2216 YHG=2194>was " XBD=478 XHG=407 YBD=2216 YHG=2184>less " XBD=591 XHG=494 YBD=2215 YHG=2184>than " XBD=630 XHG=608 YBD=2215 YHG=2186>4 " XBD=736 XHG=647 YBD=2225 YHG=2193>mg., " XBD=921 XHG=752 YBD=2216 YHG=2184>between " XBD=961 XHG=939 YBD=2215 YHG=2185>4 " XBD=1055 XHG=978 YBD=2216 YHG=2184>and " XBD=1114 XHG=1075 YBD=2215 YHG=2186>I mg., " XBD=1320 XHG=1240 YBD=2216 YHG=2184>and" XBD=230 XHG=147 YBD=2261 YHG=2239>over " XBD=287 XHG=247 YBD=2260 YHG=2231>11 " XBD=377 XHG=304 YBD=2270 YHG=2238>mg. " XBD=460 XHG=393 YBD=2269 YHG=2238>per " XBD=664 XHG=478 YBD=2261 YHG=2230>100 c.cm. " XBD=761 XHG=716 YBD=2260 YHG=2229>In " XBD=842 XHG=775 YBD=2260 YHG=2229>the " XBD=938 XHG=857 YBD=2260 YHG=2228>first " XBD=1072 XHG=953 YBD=2269 YHG=2238>group " XBD=1229 XHG=1090 YBD=2269 YHG=2229>dosage " XBD=1320 XHG=1242 YBD=2261 YHG=2238>was" XBD=336 XHG=146 YBD=2314 YHG=2274>gradually " XBD=550 XHG=358 YBD=2305 YHG=2273>increased " XBD=672 XHG=574 YBD=2304 YHG=2273>until " XBD=719 XHG=696 YBD=2304 YHG=2282>a " XBD=866 XHG=743 YBD=2305 YHG=2282>serum " XBD=1136 XHG=890 YBD=2313 YHG=2273>thiocyanate " XBD=1256 XHG=1158 YBD=2305 YHG=2273>level " XBD=1320 XHG=1281 YBD=2305 YHG=2273>of" XBD=231 XHG=146 YBD=2349 YHG=2319>5-12 " XBD=321 XHG=247 YBD=2358 YHG=2328>mg. " XBD=415 XHG=337 YBD=2349 YHG=2328>was " XBD=638 XHG=433 YBD=2356 YHG=2318>obtained ; " XBD=708 XHG=669 YBD=2349 YHG=2318>in " XBD=790 XHG=723 YBD=2349 YHG=2317>the " XBD=945 XHG=806 YBD=2349 YHG=2318>second " XBD=1080 XHG=961 YBD=2358 YHG=2327>group " XBD=1164 XHG=1097 YBD=2349 YHG=2318>the " XBD=1321 XHG=1182 YBD=2359 YHG=2318>dosage" XBD=216 XHG=144 YBD=2393 YHG=2371>was " XBD=393 XHG=232 YBD=2393 YHG=2362>reduced " XBD=548 XHG=412 YBD=2402 YHG=2362>during " XBD=631 XHG=564 YBD=2393 YHG=2362>the " XBD=787 XHG=649 YBD=2393 YHG=2362>second " XBD=908 XHG=804 YBD=2393 YHG=2362>week " XBD=967 XHG=926 YBD=2393 YHG=2364>to |>" XBD=1046 XHG=988 YBD=2393 YHG=2362>0’2 " XBD=1100 XHG=1065 YBD=2402 YHG=2372>g. " XBD=1225 XHG=1122 YBD=2401 YHG=2362>daily " XBD=1321 XHG=1244 YBD=2393 YHG=2362>and" XBD=405 XHG=146 YBD=2446 YHG=2406>subsequently " XBD=644 XHG=435 YBD=2437 YHG=2406>controlled " XBD=726 XHG=674 YBD=2446 YHG=2406>by " XBD=993 XHG=757 YBD=2438 YHG=2406>estimations " XBD=1064 XHG=1025 YBD=2437 YHG=2406>of " XBD=1166 XHG=1100 YBD=2437 YHG=2406>the " XBD=1320 XHG=1198 YBD=2437 YHG=2415>serum" XBD=407 XHG=144 YBD=2491 YHG=2450>thiocyanate ; " XBD=476 XHG=436 YBD=2481 YHG=2450>in " XBD=559 XHG=492 YBD=2482 YHG=2450>the " XBD=678 XHG=574 YBD=2482 YHG=2450>third " XBD=814 XHG=694 YBD=2491 YHG=2460>group " XBD=862 XHG=831 YBD=2482 YHG=2451>it " XBD=955 XHG=877 YBD=2482 YHG=2460>was " XBD=1133 XHG=970 YBD=2482 YHG=2450>reduced " XBD=1191 XHG=1149 YBD=2482 YHG=2452>to 0- " XBD=1320 XHG=1249 YBD=2491 YHG=2452>1 g." XBD=225 XHG=145 YBD=2527 YHG=2495>four " XBD=352 XHG=242 YBD=2527 YHG=2495>times " XBD=396 XHG=372 YBD=2526 YHG=2504>a " XBD=518 XHG=413 YBD=2527 YHG=2494>week " XBD=614 XHG=537 YBD=2526 YHG=2495>and " XBD=726 XHG=633 YBD=2526 YHG=2495>then " XBD=958 XHG=746 YBD=2536 YHG=2494>cautiously " XBD=1101 XHG=976 YBD=2526 YHG=2494>raised " XBD=1322 XHG=1121 YBD=2536 YHG=2494>according" XBD=184 XHG=146 YBD=2571 YHG=2541>to " XBD=266 XHG=203 YBD=2571 YHG=2539>the " XBD=408 XHG=286 YBD=2571 YHG=2549>serum " XBD=673 XHG=426 YBD=2580 YHG=2539>thiocyanate " XBD=819 XHG=691 YBD=2572 YHG=2539>levels. " XBD=971 XHG=871 YBD=2571 YHG=2538>Once " XBD=1056 XHG=989 YBD=2571 YHG=2539>the " XBD=1224 XHG=1075 YBD=2580 YHG=2539>patient " XBD=1320 XHG=1242 YBD=2572 YHG=2549>was" XBD=362 XHG=149 YBD=2624 YHG=2584>discharged " XBD=472 XHG=372 YBD=2616 YHG=2584>from " XBD=668 XHG=489 YBD=2624 YHG=2583>hospital, " XBD=807 XHG=683 YBD=2616 YHG=2593>serum " XBD=1071 XHG=825 YBD=2624 YHG=2585>thiocyanate " XBD=1320 XHG=1084 YBD=2616 YHG=2584>estimations" XBD=235 XHG=147 YBD=2660 YHG=2637>were " XBD=391 XHG=248 YBD=2660 YHG=2628>carried " XBD=472 XHG=406 YBD=2660 YHG=2630>out " XBD=556 XHG=485 YBD=2660 YHG=2628>less " XBD=688 XHG=572 YBD=2665 YHG=2628>often, " XBD=782 XHG=705 YBD=2660 YHG=2629>and " XBD=834 XHG=794 YBD=2660 YHG=2629>in " XBD=948 XHG=849 YBD=2660 YHG=2630>most " XBD=1065 XHG=963 YBD=2660 YHG=2638>cases " XBD=1145 XHG=1079 YBD=2660 YHG=2629>the " XBD=1319 XHG=1158 YBD=2668 YHG=2629>require-" XBD=262 XHG=147 YBD=2704 YHG=2675>ments " XBD=325 XHG=287 YBD=2703 YHG=2672>of " XBD=558 XHG=346 YBD=2713 YHG=2673>potassium " XBD=828 XHG=581 YBD=2713 YHG=2672>thiocyanate " XBD=946 XHG=850 YBD=2705 YHG=2682>were " XBD=1088 XHG=967 YBD=2704 YHG=2672>found " XBD=1152 XHG=1111 YBD=2704 YHG=2674>to " XBD=1320 XHG=1176 YBD=2704 YHG=2673>remain" XBD=334 XHG=146 YBD=2757 YHG=2712>relatively " XBD=552 XHG=364 YBD=2748 YHG=2719>constant. " XBD=654 XHG=606 YBD=2748 YHG=2717>Of " XBD=749 XHG=682 YBD=2748 YHG=2717>the " XBD=824 XHG=779 YBD=2749 YHG=2718>25 " XBD=1021 XHG=853 YBD=2758 YHG=2718>patients " XBD=1316 XHG=1049 YBD=2757 YHG=2717>investigated," XBD=186 XHG=150 YBD=2791 YHG=2762>11 " XBD=355 XHG=208 YBD=2792 YHG=2760>showed " XBD=398 XHG=376 YBD=2792 YHG=2771>a " XBD=484 XHG=416 YBD=2792 YHG=2761>fall " XBD=543 XHG=504 YBD=2793 YHG=2762>of " XBD=613 XHG=568 YBD=2793 YHG=2762>40 " XBD=724 XHG=634 YBD=2792 YHG=2771>mm. " XBD=809 XHG=747 YBD=2802 YHG=2761>Hg " XBD=871 XHG=830 YBD=2793 YHG=2772>or " XBD=993 XHG=891 YBD=2793 YHG=2772>more " XBD=1051 XHG=1012 YBD=2793 YHG=2762>in " XBD=1141 XHG=1075 YBD=2793 YHG=2761>the " XBD=1320 XHG=1166 YBD=2801 YHG=2760>systolic" XBD=307 XHG=146 YBD=2845 YHG=2814>pressure " XBD=403 XHG=326 YBD=2837 YHG=2805>and " XBD=468 XHG=423 YBD=2837 YHG=2806>20 " XBD=578 XHG=488 YBD=2837 YHG=2816>mm. " XBD=642 XHG=600 YBD=2837 YHG=2816>or " XBD=764 XHG=662 YBD=2837 YHG=2815>more " XBD=822 XHG=783 YBD=2837 YHG=2806>in " XBD=907 XHG=841 YBD=2837 YHG=2806>the " XBD=1101 XHG=929 YBD=2837 YHG=2806>diastolic " XBD=1313 XHG=1120 YBD=2846 YHG=2815>pressure ;" XBD=167 XHG=148 YBD=2880 YHG=2851>6 " XBD=331 XHG=185 YBD=2881 YHG=2849>showed " XBD=500 XHG=351 YBD=2881 YHG=2850>smaller " XBD=617 XHG=517 YBD=2887 YHG=2850>falls; " XBD=744 XHG=635 YBD=2881 YHG=2849>while " XBD=786 XHG=765 YBD=2881 YHG=2852>8 " XBD=903 XHG=806 YBD=2891 YHG=2860>gave " XBD=971 XHG=921 YBD=2881 YHG=2860>no " XBD=1179 XHG=991 YBD=2891 YHG=2860>response. " XBD=1268 XHG=1231 YBD=2881 YHG=2850>It " XBD=1318 XHG=1286 YBD=2881 YHG=2850>is" XBD=350 XHG=148 YBD=2934 YHG=2893>significant " XBD=460 XHG=372 YBD=2925 YHG=2894>that " XBD=523 XHG=484 YBD=2925 YHG=2895>of " XBD=611 XHG=544 YBD=2926 YHG=2894>the " XBD=679 XHG=638 YBD=2924 YHG=2894>12 " XBD=869 XHG=701 YBD=2934 YHG=2894>patients " XBD=984 XHG=891 YBD=2926 YHG=2895>with " XBD=1056 XHG=1007 YBD=2926 YHG=2904>no " XBD=1257 XHG=1079 YBD=2926 YHG=2894>evidence " XBD=1321 XHG=1281 YBD=2926 YHG=2894>of" XBD=301 XHG=148 YBD=2978 YHG=2938>activity " XBD=549 XHG=311 YBD=2978 YHG=2938>(hsematuria " XBD=606 XHG=565 YBD=2969 YHG=2948>or " XBD=757 XHG=619 YBD=2970 YHG=2938>retinal |>" XBD=1061 XHG=770 YBD=2979 YHG=2938>haemorrhages) " XBD=1162 XHG=1074 YBD=2979 YHG=2939>only " XBD=1194 XHG=1177 YBD=2969 YHG=2940>1 " XBD=1321 XHG=1205 YBD=2970 YHG=2938>failed" XBD=185 XHG=147 YBD=3013 YHG=2983>to " XBD=312 XHG=212 YBD=3014 YHG=2982>show " XBD=361 XHG=339 YBD=3013 YHG=2992>a " XBD=454 XHG=386 YBD=3013 YHG=2982>fall " XBD=520 XHG=481 YBD=3014 YHG=2983>of " XBD=593 XHG=546 YBD=3014 YHG=2984>40 " XBD=710 XHG=619 YBD=3014 YHG=2992>mm. " XBD=776 XHG=736 YBD=3013 YHG=2982>in " XBD=956 XHG=802 YBD=3022 YHG=2983>systolic " XBD=1061 XHG=984 YBD=3014 YHG=2983>and " XBD=1134 XHG=1088 YBD=3015 YHG=2983>20 " XBD=1250 XHG=1160 YBD=3014 YHG=2992>mm. " XBD=1318 XHG=1278 YBD=3013 YHG=2982>in" XBD=312 XHG=149 YBD=3058 YHG=3026>diastolic " XBD=514 XHG=333 YBD=3066 YHG=3036>pressure, " XBD=702 XHG=536 YBD=3058 YHG=3027>whereas " XBD=765 XHG=726 YBD=3058 YHG=3027>of " XBD=853 XHG=787 YBD=3058 YHG=3026>the " XBD=920 XHG=880 YBD=3058 YHG=3027>12 " XBD=1111 XHG=944 YBD=3067 YHG=3027>patients " XBD=1227 XHG=1133 YBD=3060 YHG=3027>with " XBD=1321 XHG=1250 YBD=3058 YHG=3036>one" XBD=187 XHG=149 YBD=3101 YHG=3079>or " XBD=292 XHG=199 YBD=3102 YHG=3071>both " XBD=345 XHG=307 YBD=3102 YHG=3071>of " XBD=463 XHG=358 YBD=3103 YHG=3071>these " XBD=577 XHG=477 YBD=3112 YHG=3072>signs " XBD=631 XHG=592 YBD=3103 YHG=3072>of " XBD=807 XHG=646 YBD=3111 YHG=3071>activity " XBD=918 XHG=820 YBD=3103 YHG=3080>none " XBD=1085 XHG=932 YBD=3103 YHG=3071>showed " XBD=1193 XHG=1099 YBD=3103 YHG=3072>such " XBD=1229 XHG=1207 YBD=3102 YHG=3081>a " XBD=1322 XHG=1242 YBD=3103 YHG=3071>fall." XBD=417 XHG=150 YBD=3155 YHG=3113>Symptomatic " XBD=715 XHG=437 YBD=3155 YHG=3116>improvement " XBD=813 XHG=735 YBD=3147 YHG=3125>was " XBD=938 XHG=835 YBD=3147 YHG=3125>more " XBD=1120 XHG=959 YBD=3156 YHG=3116>striking " XBD=1236 XHG=1139 YBD=3147 YHG=3116>than " XBD=1324 XHG=1257 YBD=3147 YHG=3116>the" XBD=211 XHG=147 YBD=3189 YHG=3158>fall " XBD=266 XHG=228 YBD=3189 YHG=3159>in " XBD=609 XHG=286 YBD=3199 YHG=3159>blood-pressure ; " XBD=736 XHG=646 YBD=3191 YHG=3159>thus " XBD=803 XHG=761 YBD=3190 YHG=3161>14 " XBD=892 XHG=825 YBD=3190 YHG=3161>out " XBD=954 XHG=915 YBD=3190 YHG=3159>of " XBD=1019 XHG=977 YBD=3190 YHG=3161>17 " XBD=1209 XHG=1041 YBD=3198 YHG=3160>patients " XBD=1322 XHG=1228 YBD=3191 YHG=3159>with" XBD=331 XHG=147 YBD=3233 YHG=3201>headache " XBD=519 XHG=349 YBD=3234 YHG=3203>received " XBD=651 XHG=536 YBD=3240 YHG=3204>relief, " XBD=712 XHG=672 YBD=3234 YHG=3212>as " XBD=798 XHG=733 YBD=3234 YHG=3203>did " XBD=839 XHG=818 YBD=3233 YHG=3205>5 " XBD=926 XHG=859 YBD=3234 YHG=3204>out " XBD=985 XHG=947 YBD=3233 YHG=3203>of " XBD=1026 XHG=1006 YBD=3233 YHG=3204>6 " XBD=1212 XHG=1045 YBD=3242 YHG=3203>patients " XBD=1324 XHG=1230 YBD=3234 YHG=3203>with" XBD=300 XHG=149 YBD=3286 YHG=3246>vertigo, " XBD=410 XHG=334 YBD=3277 YHG=3246>and " XBD=466 XHG=444 YBD=3278 YHG=3248>5 " XBD=568 XHG=502 YBD=3278 YHG=3248>out " XBD=643 XHG=604 YBD=3278 YHG=3247>of " XBD=698 XHG=678 YBD=3278 YHG=3249>8 " XBD=900 XHG=732 YBD=3286 YHG=3246>patients " XBD=1027 XHG=933 YBD=3278 YHG=3246>with " XBD=1322 XHG=1060 YBD=3286 YHG=3246>palpitations." XBD=384 XHG=149 YBD=3329 YHG=3288>Presumably " XBD=571 XHG=412 YBD=3321 YHG=3290>because " XBD=640 XHG=601 YBD=3322 YHG=3291>of " XBD=740 XHG=674 YBD=3322 YHG=3291>the " XBD=916 XHG=776 YBD=3322 YHG=3290>careful " XBD=1092 XHG=945 YBD=3321 YHG=3290>control " XBD=1171 XHG=1119 YBD=3329 YHG=3289>by " XBD=1323 XHG=1200 YBD=3321 YHG=3299>serum

6. Slater, P., Sargant, W. and Glen, M. Lancet, 1942, i, 676.7. Heath, R. G. and Powdermaker, F. J. Amer. med. Ass. 1944,

125, 111.8. D’Silva, J. L. and Evans, G. Brit. J. Urol. 1944, 16, 1.

" XBD=1612 XHG=1365 YBD=220 YHG=180>thiocyanate " XBD=1872 XHG=1623 YBD=216 YHG=180>estimations, " XBD=1988 XHG=1885 YBD=211 YHG=180>toxic " XBD=2127 XHG=2000 YBD=212 YHG=181>effects " XBD=2239 XHG=2144 YBD=213 YHG=191>were " XBD=2344 XHG=2250 YBD=218 YHG=191>rare, " XBD=2552 XHG=2358 YBD=221 YHG=182>occurring" XBD=1405 XHG=1365 YBD=256 YHG=225>in " XBD=1508 XHG=1418 YBD=264 YHG=225>only " XBD=1541 XHG=1520 YBD=254 YHG=225>2 " XBD=1733 XHG=1553 YBD=263 YHG=225>patients. " XBD=1864 XHG=1786 YBD=255 YHG=223>One " XBD=1917 XHG=1878 YBD=254 YHG=224>of " XBD=2038 XHG=1931 YBD=254 YHG=224>these " XBD=2116 XHG=2048 YBD=255 YHG=224>felt " XBD=2355 XHG=2128 YBD=265 YHG=225>excessively " XBD=2464 XHG=2365 YBD=256 YHG=225>tired " XBD=2553 XHG=2477 YBD=255 YHG=225>and" XBD=1586 XHG=1366 YBD=306 YHG=268>nauseated, " XBD=1676 XHG=1600 YBD=299 YHG=268>and " XBD=1930 XHG=1692 YBD=308 YHG=267>complained " XBD=1981 XHG=1942 YBD=298 YHG=268>of " XBD=2104 XHG=1995 YBD=306 YHG=267>pains " XBD=2158 XHG=2119 YBD=298 YHG=267>in " XBD=2239 XHG=2173 YBD=299 YHG=268>the " XBD=2330 XHG=2252 YBD=309 YHG=267>legs " XBD=2419 XHG=2342 YBD=299 YHG=268>and " XBD=2553 XHG=2433 YBD=307 YHG=268>impo-" XBD=1474 XHG=1366 YBD=344 YHG=314>tence " XBD=1601 XHG=1492 YBD=344 YHG=312>when " XBD=1691 XHG=1625 YBD=343 YHG=312>the " XBD=1838 XHG=1714 YBD=343 YHG=321>serum |>" XBD=2108 XHG=1861 YBD=351 YHG=311>thiocyanate " XBD=2207 XHG=2129 YBD=342 YHG=321>was " XBD=2277 XHG=2235 YBD=342 YHG=313>18 " XBD=2375 XHG=2301 YBD=352 YHG=321>mg. " XBD=2461 XHG=2393 YBD=351 YHG=321>per " XBD=2554 XHG=2488 YBD=342 YHG=313>100" XBD=1500 XHG=1368 YBD=394 YHG=366>c.cm. ; " XBD=1606 XHG=1540 YBD=387 YHG=356>the " XBD=1741 XHG=1632 YBD=387 YHG=356>other " XBD=2004 XHG=1766 YBD=395 YHG=355>complained " XBD=2069 XHG=2031 YBD=386 YHG=355>of " XBD=2273 XHG=2092 YBD=386 YHG=354>tiredness " XBD=2377 XHG=2300 YBD=386 YHG=356>and " XBD=2554 XHG=2400 YBD=386 YHG=364>nausea." XBD=1430 XHG=1368 YBD=431 YHG=399>All " XBD=1527 XHG=1450 YBD=431 YHG=400>this " XBD=1580 XHG=1549 YBD=431 YHG=400>is " XBD=1845 XHG=1603 YBD=439 YHG=400>satisfactory " XBD=1910 XHG=1869 YBD=430 YHG=409>as " XBD=1995 XHG=1935 YBD=430 YHG=400>far " XBD=2059 XHG=2018 YBD=430 YHG=408>as " XBD=2116 XHG=2084 YBD=429 YHG=399>it " XBD=2238 XHG=2138 YBD=439 YHG=408>goes, " XBD=2331 XHG=2261 YBD=430 YHG=398>but " XBD=2420 XHG=2352 YBD=430 YHG=399>the " XBD=2555 XHG=2445 YBD=430 YHG=399>series" XBD=1399 XHG=1368 YBD=474 YHG=443>is " XBD=1504 XHG=1412 YBD=483 YHG=452>very " XBD=1627 XHG=1517 YBD=475 YHG=444>small " XBD=1716 XHG=1639 YBD=475 YHG=444>and " XBD=1783 XHG=1727 YBD=475 YHG=453>we " XBD=1895 XHG=1796 YBD=475 YHG=443>have " XBD=1956 XHG=1907 YBD=474 YHG=453>no " XBD=2148 XHG=1970 YBD=474 YHG=443>evidence " XBD=2200 XHG=2161 YBD=473 YHG=442>of " XBD=2299 XHG=2212 YBD=473 YHG=442>how " XBD=2399 XHG=2308 YBD=482 YHG=443>long " XBD=2476 XHG=2410 YBD=473 YHG=443>the " XBD=2556 XHG=2488 YBD=473 YHG=443>fall" XBD=1408 XHG=1369 YBD=517 YHG=487>in " XBD=1589 XHG=1420 YBD=526 YHG=496>pressure " XBD=1630 XHG=1600 YBD=518 YHG=488>is " XBD=1878 XHG=1644 YBD=519 YHG=487>maintained " XBD=1933 XHG=1891 YBD=518 YHG=497>or " XBD=2047 XHG=1943 YBD=518 YHG=487>what " XBD=2089 XHG=2058 YBD=517 YHG=487>is " XBD=2150 XHG=2101 YBD=517 YHG=486>its " XBD=2271 XHG=2162 YBD=517 YHG=485>effect " XBD=2333 XHG=2285 YBD=516 YHG=495>on " XBD=2553 XHG=2345 YBD=526 YHG=487>prognosis." XBD=1531 XHG=1370 YBD=561 YHG=531>Further " XBD=1574 XHG=1543 YBD=561 YHG=531>it " XBD=1723 XHG=1587 YBD=562 YHG=531>should " XBD=1782 XHG=1736 YBD=562 YHG=531>be " XBD=1912 XHG=1794 YBD=562 YHG=531>noted " XBD=2012 XHG=1924 YBD=562 YHG=531>that " XBD=2165 XHG=2025 YBD=562 YHG=529>careful " XBD=2324 XHG=2178 YBD=561 YHG=529>control " XBD=2365 XHG=2335 YBD=560 YHG=530>is " XBD=2554 XHG=2382 YBD=569 YHG=529>required" XBD=1422 XHG=1369 YBD=614 YHG=575>by " XBD=1659 XHG=1438 YBD=615 YHG=574>laboratory " XBD=1853 XHG=1677 YBD=607 YHG=575>methods " XBD=1958 XHG=1870 YBD=606 YHG=575>that " XBD=2045 XHG=1978 YBD=606 YHG=580>are " XBD=2205 XHG=2056 YBD=614 YHG=574>usually " XBD=2290 XHG=2222 YBD=605 YHG=575>not " XBD=2495 XHG=2309 YBD=605 YHG=573>available " XBD=2554 XHG=2512 YBD=605 YHG=575>to" XBD=1437 XHG=1349 YBD=649 YHG=614>the " XBD=1704 XHG=1457 YBD=658 YHG=619>practitioner " XBD=1766 XHG=1725 YBD=650 YHG=629>or " XBD=1881 XHG=1785 YBD=651 YHG=629>even " XBD=1941 XHG=1900 YBD=651 YHG=621>to " XBD=2079 XHG=1963 YBD=659 YHG=629>many " XBD=2209 XHG=2099 YBD=650 YHG=618>small " XBD=2425 XHG=2230 YBD=658 YHG=617>hospitals.

TREATMENT OF BACTERIAL ENDOCARDITIS

" XBD=1553 XHG=1422 YBD=784 YHG=752>WHEN " XBD=1685 XHG=1575 YBD=783 YHG=751>faced " XBD=1799 XHG=1705 YBD=783 YHG=751>with " XBD=1870 XHG=1820 YBD=783 YHG=761>an " XBD=2029 XHG=1892 YBD=785 YHG=752>almost " XBD=2263 XHG=2050 YBD=793 YHG=752>invariably " XBD=2380 XHG=2282 YBD=783 YHG=751>fatal " XBD=2557 XHG=2402 YBD=788 YHG=751>disease," XBD=1442 XHG=1375 YBD=828 YHG=796>the " XBD=1659 XHG=1460 YBD=836 YHG=795>physician " XBD=1708 XHG=1677 YBD=827 YHG=796>is " XBD=1829 XHG=1728 YBD=836 YHG=795>right " XBD=1891 XHG=1849 YBD=827 YHG=798>to " XBD=1975 XHG=1910 YBD=836 YHG=798>try " XBD=2108 XHG=1994 YBD=837 YHG=806>every " XBD=2210 XHG=2127 YBD=829 YHG=806>new " XBD=2395 XHG=2227 YBD=836 YHG=806>weapon, " XBD=2512 XHG=2417 YBD=827 YHG=805>even " XBD=2561 XHG=2531 YBD=827 YHG=796>if" XBD=1406 XHG=1375 YBD=872 YHG=841>it " XBD=1566 XHG=1431 YBD=871 YHG=840>carries " XBD=1639 XHG=1589 YBD=871 YHG=840>its " XBD=1747 XHG=1664 YBD=871 YHG=849>own " XBD=1878 XHG=1770 YBD=871 YHG=840>risks. " XBD=2007 XHG=1929 YBD=872 YHG=840>But " XBD=2069 XHG=2029 YBD=872 YHG=841>in " XBD=2275 XHG=2092 YBD=881 YHG=841>assessing " XBD=2364 XHG=2298 YBD=872 YHG=841>the " XBD=2498 XHG=2387 YBD=871 YHG=840>value " XBD=2562 XHG=2522 YBD=871 YHG=840>of" XBD=1469 XHG=1377 YBD=916 YHG=884>such " XBD=1673 XHG=1497 YBD=924 YHG=887>weapons " XBD=1741 XHG=1700 YBD=915 YHG=884>in " XBD=1951 XHG=1769 YBD=916 YHG=884>subacute " XBD=2160 XHG=1979 YBD=916 YHG=884>bacterial " XBD=2439 XHG=2189 YBD=917 YHG=884>endocarditis " XBD=2500 XHG=2468 YBD=916 YHG=885>it " XBD=2561 XHG=2528 YBD=916 YHG=884>is" XBD=1634 XHG=1375 YBD=969 YHG=928>unjustifiable " XBD=1690 XHG=1650 YBD=960 YHG=929>to " XBD=1833 XHG=1706 YBD=969 YHG=928>ignore " XBD=1916 XHG=1849 YBD=960 YHG=928>the " XBD=2019 XHG=1929 YBD=970 YHG=928>long " XBD=2244 XHG=2032 YBD=961 YHG=930>remissions " XBD=2347 XHG=2259 YBD=961 YHG=930>that " XBD=2433 XHG=2363 YBD=961 YHG=939>can " XBD=2561 XHG=2450 YBD=961 YHG=938>occur" XBD=1569 XHG=1375 YBD=1006 YHG=973>whatever " XBD=1802 XHG=1594 YBD=1005 YHG=974>treatment " XBD=1860 XHG=1828 YBD=1005 YHG=973>is " XBD=2085 XHG=1888 YBD=1014 YHG=973>adopted. " XBD=2155 XHG=2118 YBD=1005 YHG=973>It " XBD=2213 XHG=2182 YBD=1005 YHG=974>is " XBD=2326 XHG=2240 YBD=1006 YHG=984>now " XBD=2425 XHG=2350 YBD=1006 YHG=974>five " XBD=2570 XHG=2450 YBD=1015 YHG=979>years’" XBD=1477 XHG=1377 YBD=1050 YHG=1019>since " XBD=1579 XHG=1511 YBD=1049 YHG=1018>the " XBD=1873 XHG=1613 YBD=1050 YHG=1017>introduction " XBD=1949 XHG=1909 YBD=1048 YHG=1017>of " XBD=2007 XHG=1984 YBD=1049 YHG=1027>a " XBD=2240 XHG=2042 YBD=1058 YHG=1017>relatively " XBD=2367 XHG=2273 YBD=1059 YHG=1028>pure " XBD=2560 XHG=2402 YBD=1060 YHG=1018>heparin" XBD=1582 XHG=1375 YBD=1104 YHG=1062>permitted " XBD=1814 XHG=1613 YBD=1095 YHG=1062>American workers " XBD=2098 XHG=2011 YBD=1094 YHG=1062>1 to " XBD=2195 XHG=2130 YBD=1102 YHG=1063>try " XBD=2292 XHG=2226 YBD=1094 YHG=1062>the " XBD=2429 XHG=2320 YBD=1095 YHG=1063>effect " XBD=2502 XHG=2463 YBD=1095 YHG=1063>of " XBD=2557 XHG=2534 YBD=1095 YHG=1073>a" XBD=1635 XHG=1378 YBD=1139 YHG=1107>combination " XBD=1699 XHG=1660 YBD=1138 YHG=1107>of " XBD=2027 XHG=1721 YBD=1148 YHG=1107>sulphonamides " XBD=2127 XHG=2050 YBD=1138 YHG=1106>and " XBD=2317 XHG=2148 YBD=1146 YHG=1107>heparin, " XBD=2464 XHG=2341 YBD=1139 YHG=1107>which " XBD=2564 XHG=2485 YBD=1139 YHG=1108>had" XBD=1537 XHG=1378 YBD=1183 YHG=1152>obvious " XBD=1772 XHG=1550 YBD=1183 YHG=1152>theoretical " XBD=2036 XHG=1784 YBD=1192 YHG=1151>possibilities, " XBD=2091 XHG=2051 YBD=1183 YHG=1151>in " XBD=2285 XHG=2104 YBD=1182 YHG=1151>bacterial " XBD=2561 XHG=2297 YBD=1184 YHG=1151>endocarditis." XBD=1575 XHG=1381 YBD=1237 YHG=1196>Repeated |>" XBD=1794 XHG=1583 YBD=1237 YHG=1196>warnings 2 of " XBD=1931 XHG=1865 YBD=1227 YHG=1196>the " XBD=2106 XHG=1948 YBD=1236 YHG=1195>dangers " XBD=2158 XHG=2119 YBD=1226 YHG=1195>of " XBD=2330 XHG=2173 YBD=1235 YHG=1195>heparin " XBD=2507 XHG=2345 YBD=1237 YHG=1196>therapy " XBD=2563 XHG=2522 YBD=1228 YHG=1196>in" XBD=1472 XHG=1380 YBD=1272 YHG=1240>such " XBD=1592 XHG=1489 YBD=1272 YHG=1250>cases " XBD=1793 XHG=1608 YBD=1278 YHG=1240>followed, " XBD=1884 XHG=1812 YBD=1272 YHG=1241>but " XBD=1932 XHG=1900 YBD=1272 YHG=1240>it " XBD=2153 XHG=1950 YBD=1272 YHG=1239>continued " XBD=2211 XHG=2170 YBD=1271 YHG=1241>to " XBD=2276 XHG=2229 YBD=1271 YHG=1240>be " XBD=2385 XHG=2292 YBD=1272 YHG=1240>used " XBD=2561 XHG=2403 YBD=1273 YHG=1240>because" XBD=1408 XHG=1377 YBD=1317 YHG=1286>it " XBD=1516 XHG=1438 YBD=1317 YHG=1294>was " XBD=1613 XHG=1547 YBD=1316 YHG=1284>the " XBD=1734 XHG=1644 YBD=1325 YHG=1284>only " XBD=1874 XHG=1762 YBD=1325 YHG=1285>hope. " XBD=2048 XHG=1925 YBD=1316 YHG=1284>Cooke " XBD=2155 XHG=2078 YBD=1316 YHG=1283>and Taylor " XBD=2448 XHG=2331 YBD=1316 YHG=1283>3 last " XBD=2565 XHG=2472 YBD=1325 YHG=1294>year" XBD=1621 XHG=1379 YBD=1369 YHG=1328>reported ’on " XBD=1685 XHG=1639 YBD=1360 YHG=1329>20 " XBD=1805 XHG=1702 YBD=1361 YHG=1338>cases " XBD=1970 XHG=1821 YBD=1361 YHG=1329>treated " XBD=2079 XHG=1985 YBD=1361 YHG=1328>with " XBD=2411 XHG=2095 YBD=1369 YHG=1329>sulphonamides, " XBD=2469 XHG=2429 YBD=1360 YHG=1329>in " XBD=2566 XHG=2487 YBD=1361 YHG=1329>5 -of" XBD=1500 XHG=1377 YBD=1405 YHG=1374>which " XBD=1623 XHG=1528 YBD=1414 YHG=1373>they " XBD=1741 XHG=1645 YBD=1406 YHG=1383>were " XBD=1964 XHG=1766 YBD=1405 YHG=1373>combined " XBD=2080 XHG=1987 YBD=1406 YHG=1373>with " XBD=2272 XHG=2103 YBD=1414 YHG=1373>heparin. " XBD=2383 XHG=2322 YBD=1405 YHG=1373>All " XBD=2516 XHG=2410 YBD=1406 YHG=1373>these " XBD=2563 XHG=2542 YBD=1405 YHG=1375>5" XBD=1546 XHG=1378 YBD=1459 YHG=1418>patients " XBD=1663 XHG=1565 YBD=1456 YHG=1417>died, " XBD=1758 XHG=1681 YBD=1450 YHG=1418>and " XBD=1815 XHG=1774 YBD=1450 YHG=1417>in " XBD=1902 XHG=1832 YBD=1450 YHG=1428>one " XBD=2004 XHG=1920 YBD=1450 YHG=1427>case " XBD=2137 XHG=2022 YBD=1450 YHG=1418>death " XBD=2230 XHG=2153 YBD=1450 YHG=1427>was " XBD=2321 XHG=2248 YBD=1450 YHG=1418>due " XBD=2379 XHG=2338 YBD=1450 YHG=1419>to " XBD=2563 XHG=2398 YBD=1451 YHG=1418>cerebral" XBD=1634 XHG=1379 YBD=1504 YHG=1462>haemorrhage " XBD=1801 XHG=1665 YBD=1495 YHG=1463>almost " XBD=2014 XHG=1831 YBD=1503 YHG=1462>certainly " XBD=2291 XHG=2043 YBD=1495 YHG=1462>attributable " XBD=2361 XHG=2320 YBD=1495 YHG=1465>to " XBD=2561 XHG=2390 YBD=1504 YHG=1463>heparin." XBD=1499 XHG=1380 YBD=1540 YHG=1508>These " XBD=1734 XHG=1540 YBD=1540 YHG=1502>observers " XBD=1954 XHG=1774 YBD=1539 YHG=1507>conclude " XBD=2080 XHG=1991 YBD=1539 YHG=1502>that " XBD=2364 XHG=2121 YBD=1540 YHG=1508>intravenous " XBD=2561 XHG=2404 YBD=1548 YHG=1508>heparin" XBD=1515 XHG=1380 YBD=1585 YHG=1552>should " XBD=1605 XHG=1537 YBD=1583 YHG=1553>not " XBD=1675 XHG=1627 YBD=1584 YHG=1552>be " XBD=1802 XHG=1696 YBD=1588 YHG=1551>used, " XBD=1848 XHG=1825 YBD=1584 YHG=1561>a " XBD=1967 XHG=1870 YBD=1584 YHG=1552>view " XBD=2122 XHG=1987 YBD=1584 YHG=1552>shared " XBD=2197 XHG=2144 YBD=1593 YHG=1552>by " XBD=2319 XHG=2220 YBD=1584 YHG=1553>Katz " XBD=2419 XHG=2343 YBD=1584 YHG=1552>and " XBD=2565 XHG=2442 YBD=1589 YHG=1551>Elek |>" XBD=2565 XHG=2550 YBD=1570 YHG=1551>4" XBD=1463 XHG=1378 YBD=1629 YHG=1597>who " XBD=1636 XHG=1484 YBD=1628 YHG=1597>blamed " XBD=1687 XHG=1656 YBD=1628 YHG=1597>it " XBD=1767 XHG=1707 YBD=1628 YHG=1596>for " XBD=1852 XHG=1786 YBD=1628 YHG=1596>the " XBD=2038 XHG=1873 YBD=1628 YHG=1596>cerebral " XBD=2310 XHG=2056 YBD=1638 YHG=1596>haemorrhage " XBD=2418 XHG=2330 YBD=1628 YHG=1596>that " XBD=2562 XHG=2438 YBD=1629 YHG=1596>devel-" XBD=1476 XHG=1379 YBD=1682 YHG=1642>oped " XBD=1542 XHG=1502 YBD=1672 YHG=1641>in " XBD=1582 XHG=1561 YBD=1671 YHG=1641>2 " XBD=1640 XHG=1600 YBD=1672 YHG=1641>of " XBD=1722 XHG=1657 YBD=1673 YHG=1641>the " XBD=1773 XHG=1750 YBD=1673 YHG=1642>4 " XBD=1901 XHG=1799 YBD=1672 YHG=1650>cases " XBD=2021 XHG=1928 YBD=1681 YHG=1640>they " XBD=2221 XHG=2046 YBD=1682 YHG=1641>reported " XBD=2324 XHG=2247 YBD=1673 YHG=1641>and " XBD=2459 XHG=2349 YBD=1674 YHG=1641>could " XBD=2566 XHG=2484 YBD=1673 YHG=1641>find" XBD=1428 XHG=1379 YBD=1718 YHG=1696>no " XBD=1641 XHG=1463 YBD=1718 YHG=1686>evidence " XBD=1758 XHG=1670 YBD=1717 YHG=1686>that " XBD=1810 XHG=1779 YBD=1717 YHG=1685>it " XBD=1898 XHG=1832 YBD=1717 YHG=1685>did " XBD=2016 XHG=1919 YBD=1727 YHG=1686>good " XBD=2077 XHG=2037 YBD=1717 YHG=1685>in " XBD=2174 XHG=2098 YBD=1726 YHG=1695>any " XBD=2235 XHG=2196 YBD=1717 YHG=1686>of " XBD=2381 XHG=2264 YBD=1718 YHG=1686>them. " XBD=2565 XHG=2442 YBD=1718 YHG=1686>Cooke" XBD=1459 XHG=1382 YBD=1762 YHG=1730>and " XBD=1613 XHG=1476 YBD=1772 YHG=1730>Taylor " XBD=1698 XHG=1629 YBD=1771 YHG=1740>say " XBD=1801 XHG=1713 YBD=1762 YHG=1730>that " XBD=2126 XHG=1817 YBD=1771 YHG=1730>long-continued " XBD=2435 XHG=2143 YBD=1771 YHG=1730>chemotherapy " XBD=2562 XHG=2452 YBD=1762 YHG=1730>offers" XBD=1405 XHG=1383 YBD=1807 YHG=1785>a " XBD=1565 XHG=1425 YBD=1807 YHG=1775>chance " XBD=1624 XHG=1584 YBD=1807 YHG=1774>of " XBD=1730 XHG=1643 YBD=1806 YHG=1784>cure " XBD=1787 XHG=1747 YBD=1807 YHG=1775>in " XBD=1829 XHG=1807 YBD=1807 YHG=1785>a " XBD=1921 XHG=1847 YBD=1807 YHG=1775>few " XBD=2116 XHG=1936 YBD=1816 YHG=1775>patients, " XBD=2207 XHG=2137 YBD=1807 YHG=1775>but " XBD=2318 XHG=2226 YBD=1816 YHG=1775>they " XBD=2458 XHG=2338 YBD=1807 YHG=1775>admit " XBD=2564 XHG=2476 YBD=1807 YHG=1775>that" XBD=1446 XHG=1379 YBD=1851 YHG=1820>the " XBD=1557 XHG=1470 YBD=1852 YHG=1821>vast " XBD=1762 XHG=1582 YBD=1860 YHG=1819>majority " XBD=1845 XHG=1782 YBD=1852 YHG=1829>are " XBD=1937 XHG=1869 YBD=1852 YHG=1821>not " XBD=2163 XHG=1963 YBD=1852 YHG=1819>benefited. " XBD=2313 XHG=2216 YBD=1860 YHG=1820>Only " XBD=2358 XHG=2343 YBD=1851 YHG=1821>1 " XBD=2433 XHG=2394 YBD=1852 YHG=1820>of " XBD=2561 XHG=2462 YBD=1852 YHG=1819>their" XBD=1430 XHG=1384 YBD=1896 YHG=1865>20 " XBD=1621 XHG=1452 YBD=1904 YHG=1865>patients " XBD=1720 XHG=1643 YBD=1896 YHG=1874>was " XBD=1823 XHG=1745 YBD=1896 YHG=1864>still " XBD=1944 XHG=1846 YBD=1896 YHG=1864>alive " XBD=1991 XHG=1968 YBD=1896 YHG=1874>a " XBD=2105 XHG=2014 YBD=1906 YHG=1874>year " XBD=2227 XHG=2128 YBD=1896 YHG=1865>after " XBD=2442 XHG=2251 YBD=1905 YHG=1857>discharge " XBD=2564 XHG=2465 YBD=1896 YHG=1864>from" XBD=1560 XHG=1382 YBD=1949 YHG=1909>hospital, " XBD=1627 XHG=1587 YBD=1941 YHG=1909>in " XBD=1751 XHG=1654 YBD=1950 YHG=1909>spite " XBD=1818 XHG=1779 YBD=1941 YHG=1910>of " XBD=1910 XHG=1844 YBD=1941 YHG=1909>the " XBD=2073 XHG=1936 YBD=1942 YHG=1910>almost " XBD=2365 XHG=2100 YBD=1942 YHG=1910>astronomical " XBD=2499 XHG=2392 YBD=1941 YHG=1910>doses " XBD=2566 XHG=2526 YBD=1941 YHG=1909>of" XBD=1688 XHG=1383 YBD=1994 YHG=1953>sulphonamides " XBD=1943 XHG=1711 YBD=1995 YHG=1954>given-700 " XBD=2000 XHG=1965 YBD=1996 YHG=1964>g. " XBD=2065 XHG=2026 YBD=1986 YHG=1955>of " XBD=2366 XHG=2086 YBD=1996 YHG=1953>sulphadiazine " XBD=2428 XHG=2388 YBD=1985 YHG=1954>in " XBD=2565 XHG=2451 YBD=1985 YHG=1963>seven" XBD=1536 XHG=1385 YBD=2030 YHG=1999>months " XBD=1587 XHG=1555 YBD=2030 YHG=1998>is " XBD=1656 XHG=1605 YBD=2030 YHG=2008>an " XBD=1859 XHG=1674 YBD=2041 YHG=1998>example. " XBD=2071 XHG=1912 YBD=2040 YHG=2000>Reports " XBD=2187 XHG=2089 YBD=2031 YHG=2000>have " XBD=2359 XHG=2206 YBD=2040 YHG=1999>already " XBD=2565 XHG=2378 YBD=2039 YHG=1999>appeared" XBD=1424 XHG=1384 YBD=2075 YHG=2044>in " XBD=1517 XHG=1450 YBD=2074 YHG=2043>the " XBD=1688 XHG=1546 YBD=2076 YHG=2042>United " XBD=1842 XHG=1716 YBD=2076 YHG=2044>States " XBD=1920 XHG=1871 YBD=2076 YHG=2054>on " XBD=2013 XHG=1946 YBD=2075 YHG=2044>the " XBD=2106 XHG=2040 YBD=2077 YHG=2053>use " XBD=2387 XHG=2134 YBD=2085 YHG=2043>of’ penicillin " XBD=2473 XHG=2414 YBD=2075 YHG=2043>for " XBD=2566 XHG=2500 YBD=2075 YHG=2043>the" XBD=1557 XHG=1382 YBD=2129 YHG=2097>purpose. " XBD=1686 XHG=1607 YBD=2120 YHG=2088>The " XBD=1843 XHG=1707 YBD=2120 YHG=2089>official verdict " XBD=2162 XHG=2023 YBD=2121 YHG=2088>5 there " XBD=2214 XHG=2182 YBD=2120 YHG=2089>is " XBD=2321 XHG=2235 YBD=2120 YHG=2089>that " XBD=2409 XHG=2342 YBD=2120 YHG=2088>the " XBD=2565 XHG=2429 YBD=2120 YHG=2087>results" XBD=1447 XHG=1385 YBD=2165 YHG=2143>are " XBD=1751 XHG=1470 YBD=2175 YHG=2133>disappointing " XBD=1848 XHG=1771 YBD=2165 YHG=2134>and " XBD=1933 XHG=1867 YBD=2165 YHG=2133>the " XBD=2051 XHG=1955 YBD=2175 YHG=2134>drug " XBD=2205 XHG=2069 YBD=2165 YHG=2133>should " XBD=2410 XHG=2223 YBD=2166 YHG=2133>therefore " XBD=2499 XHG=2430 YBD=2164 YHG=2134>not " XBD=2567 XHG=2520 YBD=2165 YHG=2132>be" XBD=1478 XHG=1384 YBD=2211 YHG=2178>used " XBD=1542 XHG=1502 YBD=2210 YHG=2178>in " XBD=1632 XHG=1566 YBD=2210 YHG=2177>the " XBD=1800 XHG=1659 YBD=2210 YHG=2178>disease " XBD=1924 XHG=1825 YBD=2210 YHG=2178>until " XBD=2068 XHG=1947 YBD=2219 YHG=2178>larger " XBD=2255 XHG=2092 YBD=2219 YHG=2178>supplies " XBD=2344 XHG=2280 YBD=2210 YHG=2188>are " XBD=2566 XHG=2369 YBD=2209 YHG=2177>available." XBD=1463 XHG=1379 YBD=2255 YHG=2223>But " XBD=1521 XHG=1480 YBD=2254 YHG=2224>at " XBD=1603 XHG=1537 YBD=2254 YHG=2222>the " XBD=1885 XHG=1619 YBD=2263 YHG=2222>Presbyterian " XBD=2200 XHG=1903 YBD=2264 YHG=2218>Hospital,’New " XBD=2347 XHG=2216 YBD=2263 YHG=2223>YOJ;k,6 " XBD=2385 XHG=2363 YBD=2252 YHG=2223>2 " XBD=2567 XHG=2400 YBD=2263 YHG=2222>patients" XBD=1453 XHG=1385 YBD=2299 YHG=2268>out " XBD=1510 XHG=1471 YBD=2299 YHG=2268>of |>" XBD=1631 XHG=1525 YBD=2299 YHG=2267>the 5 " XBD=1759 XHG=1647 YBD=2309 YHG=2268>given " XBD=1964 XHG=1776 YBD=2308 YHG=2268>adequate " XBD=2118 XHG=1981 YBD=2309 YHG=2268>dosage " XBD=2228 XHG=2132 YBD=2299 YHG=2276>were " XBD=2470 XHG=2245 YBD=2307 YHG=2267>apparently " XBD=2570 XHG=2485 YBD=2299 YHG=2266>well" XBD=1552 XHG=1386 YBD=2343 YHG=2312>thirteen " XBD=1655 XHG=1578 YBD=2344 YHG=2312>and " XBD=1768 XHG=1680 YBD=2343 YHG=2312>nine " XBD=1947 XHG=1794 YBD=2343 YHG=2312>months " XBD=2072 XHG=1973 YBD=2344 YHG=2312>after " XBD=2284 XHG=2096 YBD=2352 YHG=2311>receiving " XBD=2466 XHG=2312 YBD=2348 YHG=2313>800,000 " XBD=2569 XHG=2493 YBD=2343 YHG=2312>and" XBD=1579 XHG=1391 YBD=2393 YHG=2357>1,400,000 " XBD=1715 XHG=1600 YBD=2393 YHG=2356>units, " XBD=1815 XHG=1738 YBD=2388 YHG=2357>and " XBD=1940 XHG=1834 YBD=2387 YHG=2356>these " XBD=2056 XHG=1961 YBD=2388 YHG=2366>were " XBD=2384 XHG=2077 YBD=2395 YHG=2355>non-haemolytic " XBD=2567 XHG=2407 YBD=2396 YHG=2357>strepto-" XBD=1511 XHG=1386 YBD=2432 YHG=2400>coccal " XBD=1638 XHG=1536 YBD=2432 YHG=2410>cases " XBD=1757 XHG=1664 YBD=2433 YHG=2400>with " XBD=1994 XHG=1782 YBD=2432 YHG=2400>rheumatic " XBD=2146 XHG=2018 YBD=2432 YHG=2400>hearts " XBD=2248 XHG=2172 YBD=2431 YHG=2400>and " XBD=2412 XHG=2274 YBD=2431 YHG=2400>emboli " XBD=2477 XHG=2437 YBD=2431 YHG=2400>in " XBD=2569 XHG=2503 YBD=2431 YHG=2400>the" XBD=1543 XHG=1384 YBD=2476 YHG=2444>femoral " XBD=1756 XHG=1591 YBD=2477 YHG=2446>arteries. |>" XBD=1976 XHG=1806 YBD=2476 YHG=2444>Another " XBD=2177 XHG=2023 YBD=2484 YHG=2444>report " XBD=2177 XHG=2165 YBD=2462 YHG=2444>7 " XBD=2431 XHG=2227 YBD=2476 YHG=2444>maintains " XBD=2568 XHG=2480 YBD=2476 YHG=2444>that" XBD=1575 XHG=1384 YBD=2529 YHG=2489>penicillin " XBD=1791 XHG=1592 YBD=2521 YHG=2489>combined " XBD=1899 XHG=1806 YBD=2520 YHG=2489>with " XBD=2072 XHG=1915 YBD=2529 YHG=2488>heparin " XBD=2180 XHG=2090 YBD=2529 YHG=2498>may " XBD=2244 XHG=2197 YBD=2521 YHG=2488>be " XBD=2301 XHG=2262 YBD=2520 YHG=2488>of " XBD=2440 XHG=2317 YBD=2521 YHG=2488>value. " XBD=2570 XHG=2491 YBD=2521 YHG=2489>The" XBD=1542 XHG=1384 YBD=2575 YHG=2534>heparin " XBD=1633 XHG=1556 YBD=2566 YHG=2544>was " XBD=1759 XHG=1648 YBD=2575 YHG=2534>given " XBD=2094 XHG=1775 YBD=2574 YHG=2533>subcutaneously " XBD=2148 XHG=2108 YBD=2565 YHG=2534>in " XBD=2271 XHG=2164 YBD=2565 YHG=2533>doses " XBD=2326 XHG=2287 YBD=2565 YHG=2533>of " XBD=2412 XHG=2344 YBD=2565 YHG=2534>300 " XBD=2503 XHG=2428 YBD=2574 YHG=2543>mg. " XBD=2570 XHG=2520 YBD=2566 YHG=2544>on" XBD=1569 XHG=1384 YBD=2611 YHG=2578>alternate " XBD=1689 XHG=1584 YBD=2619 YHG=2579>days, " XBD=1746 XHG=1704 YBD=2609 YHG=2588>or " XBD=2043 XHG=1757 YBD=2618 YHG=2578>intravenously " XBD=2094 XHG=2054 YBD=2609 YHG=2578>in " XBD=2215 XHG=2108 YBD=2609 YHG=2578>doses " XBD=2268 XHG=2228 YBD=2609 YHG=2578>of " XBD=2351 XHG=2280 YBD=2609 YHG=2578>200 " XBD=2438 XHG=2364 YBD=2620 YHG=2588>mg. " XBD=2568 XHG=2454 YBD=2620 YHG=2578>daily," XBD=1609 XHG=1384 YBD=2664 YHG=2623>apparently " XBD=1790 XHG=1627 YBD=2655 YHG=2623>without |>" XBD=1988 XHG=1808 YBD=2654 YHG=2621>ill-effect. " XBD=2117 XHG=2038 YBD=2653 YHG=2622>The " XBD=2234 XHG=2135 YBD=2653 YHG=2622>total " XBD=2389 XHG=2252 YBD=2664 YHG=2622>dosage " XBD=2448 XHG=2409 YBD=2654 YHG=2623>of " XBD=2569 XHG=2465 YBD=2663 YHG=2624>peni-" XBD=1487 XHG=1386 YBD=2698 YHG=2667>cillin " XBD=1643 XHG=1501 YBD=2708 YHG=2667>ranged " XBD=1755 XHG=1657 YBD=2698 YHG=2667>from " XBD=1927 XHG=1774 YBD=2703 YHG=2668>870,000 " XBD=1984 XHG=1942 YBD=2698 YHG=2667>to " XBD=2130 XHG=1999 YBD=2706 YHG=2666>nearly " XBD=2339 XHG=2147 YBD=2703 YHG=2667>8,000,000 " XBD=2468 XHG=2353 YBD=2699 YHG=2668>units. " XBD=2570 XHG=2521 YBD=2700 YHG=2668>Of" XBD=1451 XHG=1386 YBD=2742 YHG=2711>the " XBD=1496 XHG=1476 YBD=2742 YHG=2713>7 " XBD=1686 XHG=1519 YBD=2751 YHG=2712>patients " XBD=1869 XHG=1708 YBD=2747 YHG=2710>treated, " XBD=1932 XHG=1892 YBD=2741 YHG=2710>in " XBD=1980 XHG=1958 YBD=2742 YHG=2713>5 " XBD=2066 XHG=2000 YBD=2741 YHG=2710>the " XBD=2279 XHG=2091 YBD=2752 YHG=2710>organism " XBD=2376 XHG=2299 YBD=2743 YHG=2720>was " XBD=2424 XHG=2401 YBD=2742 YHG=2721>a " XBD=2566 XHG=2450 YBD=2752 YHG=2712>Strep." XBD=1564 XHG=1386 YBD=2791 YHG=2756>viridans, " XBD=1632 XHG=1592 YBD=2786 YHG=2755>in " XBD=1680 XHG=1665 YBD=2785 YHG=2756>1 " XBD=1734 XHG=1711 YBD=2785 YHG=2763>a " XBD=1977 XHG=1760 YBD=2794 YHG=2754>haemolytic " XBD=2297 XHG=2006 YBD=2794 YHG=2755>streptococcus, " XBD=2402 XHG=2326 YBD=2786 YHG=2755>and " XBD=2469 XHG=2429 YBD=2786 YHG=2755>in " XBD=2517 XHG=2501 YBD=2787 YHG=2757>1 " XBD=2571 XHG=2548 YBD=2787 YHG=2765>a" XBD=1683 XHG=1385 YBD=2840 YHG=2807>pneumococcus " XBD=1790 XHG=1697 YBD=2838 YHG=2799>type " XBD=1864 XHG=1806 YBD=2830 YHG=2798>27. " XBD=1961 XHG=1915 YBD=2830 YHG=2798>In " XBD=2037 XHG=1976 YBD=2835 YHG=2798>all, " XBD=2294 XHG=2053 YBD=2831 YHG=2798>sterilisation " XBD=2348 XHG=2309 YBD=2830 YHG=2799>of " XBD=2427 XHG=2361 YBD=2831 YHG=2799>the " XBD=2570 XHG=2441 YBD=2832 YHG=2800>blood-" XBD=1526 XHG=1386 YBD=2875 YHG=2845>stream " XBD=1614 XHG=1537 YBD=2875 YHG=2853>was " XBD=1808 XHG=1628 YBD=2874 YHG=2843>obtained " XBD=1913 XHG=1818 YBD=2875 YHG=2843>with " XBD=2215 XHG=1926 YBD=2883 YHG=2843>corresponding " XBD=2373 XHG=2227 YBD=2875 YHG=2843>clinical " XBD=2570 XHG=2384 YBD=2885 YHG=2844>improve-" XBD=1503 XHG=1386 YBD=2919 YHG=2889>ment. " XBD=1631 XHG=1554 YBD=2919 YHG=2887>But " XBD=1753 XHG=1656 YBD=2918 YHG=2896>none " XBD=1817 XHG=1778 YBD=2918 YHG=2887>of " XBD=1945 XHG=1839 YBD=2919 YHG=2887>them " XBD=2046 XHG=1968 YBD=2919 YHG=2887>had " XBD=2164 XHG=2069 YBD=2919 YHG=2887>been " XBD=2360 XHG=2186 YBD=2920 YHG=2887>followed " XBD=2441 XHG=2382 YBD=2921 YHG=2889>for " XBD=2568 XHG=2465 YBD=2920 YHG=2898>more" XBD=1482 XHG=1385 YBD=2963 YHG=2932>than " XBD=1521 XHG=1499 YBD=2963 YHG=2941>a " XBD=1612 XHG=1539 YBD=2964 YHG=2931>few " XBD=1782 XHG=1629 YBD=2963 YHG=2931>months " XBD=1898 XHG=1800 YBD=2963 YHG=2931>after " XBD=2109 XHG=1917 YBD=2971 YHG=2931>discharge " XBD=2225 XHG=2126 YBD=2963 YHG=2931>from " XBD=2419 XHG=2241 YBD=2973 YHG=2931>hospital, " XBD=2514 XHG=2438 YBD=2964 YHG=2934>and " XBD=2571 XHG=2531 YBD=2963 YHG=2933>in" XBD=1529 XHG=1386 YBD=3008 YHG=2975>several " XBD=1712 XHG=1551 YBD=3007 YHG=2976>massive " XBD=2022 XHG=1734 YBD=3016 YHG=2975>sulphonamide " XBD=2205 XHG=2043 YBD=3016 YHG=2976>therapy " XBD=2302 XHG=2225 YBD=3008 YHG=2985>was " XBD=2422 XHG=2324 YBD=3009 YHG=2977>tried " XBD=2571 XHG=2443 YBD=3007 YHG=2977>before" XBD=1451 XHG=1385 YBD=3052 YHG=3021>the " XBD=1677 XHG=1475 YBD=3060 YHG=3020>penicillin. " XBD=1782 XHG=1728 YBD=3051 YHG=3020>To " XBD=1926 XHG=1807 YBD=3051 YHG=3028>assess " XBD=2007 XHG=1941 YBD=3051 YHG=3020>the " XBD=2259 XHG=2024 YBD=3060 YHG=3019>significance " XBD=2315 XHG=2276 YBD=3053 YHG=3021>of " XBD=2423 XHG=2330 YBD=3053 YHG=3021>such " XBD=2572 XHG=2448 YBD=3052 YHG=3020>obser-" XBD=1536 XHG=1385 YBD=3097 YHG=3065>vations " XBD=1597 XHG=1567 YBD=3096 YHG=3064>is " XBD=1818 XHG=1629 YBD=3105 YHG=3064>well-nigh " XBD=2077 XHG=1849 YBD=3104 YHG=3064>impossible. " XBD=2228 XHG=2130 YBD=3097 YHG=3065>Here " XBD=2391 XHG=2258 YBD=3098 YHG=3065>within " XBD=2438 XHG=2416 YBD=3095 YHG=3074>a " XBD=2571 XHG=2464 YBD=3096 YHG=3064>short

1. Kelson, S. R. and White, P. D. J. Amer. med. Ass. 1939, 113,1700; Friedman, M., Hamburger, W. W. and Katz, L. N. Ibid,1939, 113, 1702.

2. Fletcher, C. M. Lancet, 1940, ii, 512; Petch, C. P. Ibid, 1940,ii, 637.

3. Cooke, W. T. and Taylor, B. Brit. Heart J. 1943, 5, 229.4. Katz, L. N. and Elek, S. R. J. Amer. med. Ass. 1944, 124, 149.5. Keefer, C. S., Blake, F. G., Marshall, B. K. jun., Lockwood, J. S.

and Wood, W. B. jun., Ibid, 1943, 122, 1217.6. Dawson, M. H. and Hobby, G. L. Ibid, 1944, 124, 611.7. Loewe, L., Rosenblatt, P., Greene, H. J. and Russell, M. Ibid,

1944, 124, 144.

Page 2: TREATMENT OF BACTERIAL ENDOCARDITIS

118

" XBD=266 XHG=133 YBD=224 YHG=184>period " XBD=336 XHG=280 YBD=214 YHG=193>we " XBD=449 XHG=350 YBD=214 YHG=183>have " XBD=571 XHG=465 YBD=214 YHG=183>three " XBD=733 XHG=587 YBD=222 YHG=185>reports " XBD=800 XHG=750 YBD=214 YHG=193>on " XBD=880 XHG=814 YBD=213 YHG=182>the " XBD=1051 XHG=896 YBD=222 YHG=183>efficacy " XBD=1107 XHG=1067 YBD=213 YHG=182>of " XBD=1321 XHG=1120 YBD=222 YHG=182>penicillin," XBD=206 XHG=135 YBD=258 YHG=237>one " XBD=362 XHG=225 YBD=266 YHG=227>calling " XBD=439 XHG=380 YBD=257 YHG=227>for " XBD=507 XHG=458 YBD=257 YHG=227>its " XBD=651 XHG=529 YBD=258 YHG=227>disuse " XBD=748 XHG=671 YBD=257 YHG=227>and " XBD=842 XHG=767 YBD=258 YHG=229>two " XBD=921 XHG=862 YBD=257 YHG=227>for " XBD=990 XHG=940 YBD=258 YHG=227>its " XBD=1087 XHG=1009 YBD=257 YHG=236>use. " XBD=1191 XHG=1138 YBD=257 YHG=225>To " XBD=1323 XHG=1212 YBD=257 YHG=226>make" XBD=332 XHG=135 YBD=301 YHG=270>confusion " XBD=487 XHG=357 YBD=306 YHG=279>worse, " XBD=564 XHG=515 YBD=302 YHG=280>no " XBD=725 XHG=592 YBD=301 YHG=280>sooner " XBD=813 XHG=751 YBD=301 YHG=279>are " XBD=895 XHG=840 YBD=301 YHG=279>we " XBD=1079 XHG=923 YBD=301 YHG=270>advised " XBD=1146 XHG=1106 YBD=301 YHG=271>to " XBD=1367 XHG=1175 YBD=301 YHG=270>discard" XBD=292 XHG=133 YBD=352 YHG=313>heparin " XBD=468 XHG=309 YBD=344 YHG=313>because " XBD=527 XHG=487 YBD=343 YHG=314>of " XBD=593 XHG=543 YBD=345 YHG=315>its " XBD=769 XHG=611 YBD=353 YHG=314>dangers " XBD=828 XHG=787 YBD=345 YHG=315>to " XBD=909 XHG=846 YBD=344 YHG=314>life " XBD=1023 XHG=926 YBD=345 YHG=314>than " XBD=1095 XHG=1040 YBD=345 YHG=323>we " XBD=1176 XHG=1114 YBD=345 YHG=323>are " XBD=1276 XHG=1193 YBD=345 YHG=314>told " XBD=1324 XHG=1292 YBD=344 YHG=314>it" XBD=167 XHG=134 YBD=387 YHG=357>is " XBD=263 XHG=197 YBD=387 YHG=356>the " XBD=413 XHG=294 YBD=387 YHG=358>secret " XBD=483 XHG=444 YBD=387 YHG=357>of " XBD=578 XHG=511 YBD=388 YHG=357>the " XBD=754 XHG=609 YBD=388 YHG=366>success " XBD=825 XHG=786 YBD=388 YHG=358>of " XBD=1043 XHG=853 YBD=396 YHG=357>penicillin " XBD=1114 XHG=1073 YBD=388 YHG=358>in " XBD=1325 XHG=1143 YBD=389 YHG=358>bacterial" XBD=402 XHG=135 YBD=431 YHG=399>endocarditis. " XBD=553 XHG=454 YBD=439 YHG=400>Only " XBD=597 XHG=576 YBD=431 YHG=410>a " XBD=837 XHG=620 YBD=440 YHG=400>large-scale " XBD=1067 XHG=861 YBD=432 YHG=401>controlled " XBD=1323 XHG=1090 YBD=441 YHG=401>experiment" XBD=207 XHG=135 YBD=474 YHG=452>can " XBD=379 XHG=221 YBD=482 YHG=443>provide " XBD=461 XHG=395 YBD=474 YHG=443>the " XBD=633 XHG=478 YBD=480 YHG=453>answer, " XBD=727 XHG=650 YBD=475 YHG=444>and " XBD=833 XHG=743 YBD=484 YHG=444>only " XBD=913 XHG=847 YBD=475 YHG=444>the " XBD=1036 XHG=931 YBD=476 YHG=444>MRC " XBD=1129 XHG=1052 YBD=477 YHG=445>and " XBD=1326 XHG=1144 YBD=476 YHG=445>National" XBD=324 XHG=135 YBD=519 YHG=486>Research " XBD=496 XHG=343 YBD=519 YHG=487>Council " XBD=574 XHG=512 YBD=518 YHG=497>are " XBD=630 XHG=591 YBD=518 YHG=487>in " XBD=670 XHG=647 YBD=518 YHG=497>a " XBD=852 XHG=687 YBD=527 YHG=488>position " XBD=910 XHG=869 YBD=519 YHG=489>to " XBD=1058 XHG=929 YBD=520 YHG=488>decide " XBD=1243 XHG=1074 YBD=520 YHG=489>whether " XBD=1345 XHG=1259 YBD=524 YHG=489>the" XBD=313 XHG=133 YBD=562 YHG=530>evidence " XBD=362 XHG=330 YBD=562 YHG=531>is " XBD=479 XHG=380 YBD=571 YHG=531>good " XBD=645 XHG=497 YBD=570 YHG=531>enough " XBD=704 XHG=663 YBD=562 YHG=533>to " XBD=859 XHG=722 YBD=571 YHG=531>justify " XBD=953 XHG=877 YBD=563 YHG=531>this " XBD=1059 XHG=972 YBD=564 YHG=534>vast " XBD=1325 XHG=1077 YBD=572 YHG=533>expenditure" XBD=174 XHG=134 YBD=605 YHG=574>of " XBD=257 XHG=191 YBD=605 YHG=574>the " XBD=422 XHG=274 YBD=605 YHG=574>limited " XBD=603 XHG=439 YBD=615 YHG=575>supplies " XBD=661 XHG=621 YBD=605 YHG=574>of " XBD=1327 XHG=677 YBD=614 YHG=571>penicillin.

VITAMIN C AND INFECTION

" XBD=322 XHG=184 YBD=740 YHG=709>THERE " XBD=466 XHG=347 YBD=740 YHG=718>seems " XBD=587 XHG=490 YBD=748 YHG=708>good " XBD=789 XHG=611 YBD=740 YHG=709>evidence " XBD=899 XHG=813 YBD=741 YHG=709>that " XBD=1086 XHG=924 YBD=741 YHG=711>vitamin " XBD=1138 XHG=1112 YBD=742 YHG=711>C " XBD=1318 XHG=1160 YBD=742 YHG=711>inhibits" XBD=201 XHG=135 YBD=784 YHG=753>the " XBD=365 XHG=218 YBD=793 YHG=753>growth " XBD=422 XHG=383 YBD=784 YHG=753>of " XBD=541 XHG=438 YBD=784 YHG=762>some " XBD=783 XHG=559 YBD=784 YHG=753>bacteria’in " XBD=900 XHG=801 YBD=785 YHG=754>vitro " XBD=991 XHG=914 YBD=786 YHG=755>and " XBD=1079 XHG=1009 YBD=786 YHG=764>can " XBD=1142 XHG=1096 YBD=786 YHG=755>be " XBD=1318 XHG=1160 YBD=786 YHG=755>bacteri-" XBD=235 XHG=136 YBD=828 YHG=797>cidal " XBD=285 XHG=246 YBD=828 YHG=798>in " XBD=486 XHG=298 YBD=837 YHG=797>adequate " XBD=813 XHG=498 YBD=829 YHG=798>concentrations. " XBD=916 XHG=865 YBD=829 YHG=798>As " XBD=1038 XHG=928 YBD=829 YHG=799>small " XBD=1098 XHG=1049 YBD=829 YHG=808>an " XBD=1268 XHG=1111 YBD=829 YHG=800>amount " XBD=1322 XHG=1280 YBD=829 YHG=808>as" XBD=183 XHG=137 YBD=872 YHG=843>80 " XBD=272 XHG=197 YBD=882 YHG=850>mg. " XBD=353 XHG=286 YBD=881 YHG=851>per " XBD=453 XHG=366 YBD=872 YHG=841>litre " XBD=505 XHG=466 YBD=871 YHG=841>of " XBD=687 XHG=519 YBD=880 YHG=850>aqueous " XBD=866 XHG=701 YBD=873 YHG=842>solution " XBD=911 XHG=880 YBD=873 YHG=843>is " XBD=1007 XHG=925 YBD=873 YHG=843>said " XBD=1061 XHG=1020 YBD=873 YHG=844>to " XBD=1123 XHG=1075 YBD=873 YHG=842>be " XBD=1319 XHG=1137 YBD=873 YHG=843>bacterio-" XBD=251 XHG=136 YBD=917 YHG=886>static " XBD=338 XHG=278 YBD=916 YHG=885>for " XBD=417 XHG=367 YBD=916 YHG=886>H. " XBD=652 XHG=443 YBD=926 YHG=886>pertussis.1 " XBD=779 XHG=700 YBD=917 YHG=886>The " XBD=970 XHG=808 YBD=917 YHG=886>vitamin " XBD=1030 XHG=999 YBD=917 YHG=887>is " XBD=1137 XHG=1060 YBD=917 YHG=886>also " XBD=1250 XHG=1168 YBD=917 YHG=886>said " XBD=1318 XHG=1277 YBD=917 YHG=888>to" XBD=296 XHG=134 YBD=969 YHG=931>prevent " XBD=389 XHG=323 YBD=960 YHG=929>the " XBD=564 XHG=417 YBD=969 YHG=929>growth " XBD=631 XHG=591 YBD=960 YHG=930>of " XBD=919 XHG=659 YBD=969 YHG=930>streptococci, " XBD=1215 XHG=948 YBD=970 YHG=930>pneumococei " XBD=1319 XHG=1243 YBD=961 YHG=930>and" XBD=441 XHG=136 YBD=1013 YHG=973>staphylocceei.2 " XBD=580 XHG=491 YBD=1004 YHG=973>This " XBD=773 XHG=610 YBD=1014 YHG=974>activity " XBD=893 XHG=803 YBD=1014 YHG=983>may " XBD=970 XHG=924 YBD=1005 YHG=974>be " XBD=1073 XHG=1002 YBD=1004 YHG=974>due " XBD=1248 XHG=1105 YBD=1012 YHG=974>mainly " XBD=1318 XHG=1277 YBD=1005 YHG=975>to" XBD=186 XHG=134 YBD=1049 YHG=1018>its " XBD=329 XHG=199 YBD=1058 YHG=1019>strong " XBD=520 XHG=340 YBD=1058 YHG=1018>reducing " XBD=672 XHG=532 YBD=1049 YHG=1018>action. " XBD=769 XHG=724 YBD=1049 YHG=1018>In " XBD=966 XHG=781 YBD=1054 YHG=1018>addition, " XBD=1142 XHG=980 YBD=1048 YHG=1017>vitamin " XBD=1183 XHG=1155 YBD=1049 YHG=1017>C " XBD=1225 XHG=1193 YBD=1048 YHG=1018>is " XBD=1320 XHG=1237 YBD=1048 YHG=1017>said" XBD=177 XHG=135 YBD=1093 YHG=1063>to " XBD=411 XHG=202 YBD=1094 YHG=1062>inactivate " XBD=540 XHG=434 YBD=1094 YHG=1072>some " XBD=744 XHG=562 YBD=1094 YHG=1062>bacterial " XBD=909 XHG=768 YBD=1098 YHG=1061>toxins, " XBD=1088 XHG=928 YBD=1101 YHG=1061>notably " XBD=1320 XHG=1106 YBD=1102 YHG=1060>diphtheria" XBD=257 XHG=134 YBD=1144 YHG=1107>toxin, " XBD=319 XHG=279 YBD=1138 YHG=1107>in " XBD=455 XHG=340 YBD=1144 YHG=1107>vitro, " XBD=555 XHG=478 YBD=1138 YHG=1107>and " XBD=616 XHG=576 YBD=1138 YHG=1108>in " XBD=739 XHG=637 YBD=1148 YHG=1107>large " XBD=939 XHG=761 YBD=1138 YHG=1107>amounts " XBD=1002 XHG=961 YBD=1137 YHG=1108>to " XBD=1137 XHG=1027 YBD=1137 YHG=1106>make " XBD=1319 XHG=1160 YBD=1136 YHG=1105>animals" XBD=239 XHG=136 YBD=1183 YHG=1160>more " XBD=441 XHG=262 YBD=1183 YHG=1151>resistant " XBD=506 XHG=465 YBD=1182 YHG=1153>to " XBD=731 XHG=531 YBD=1191 YHG=1151>injections " XBD=795 XHG=755 YBD=1181 YHG=1151>of " XBD=1034 XHG=819 YBD=1190 YHG=1150>diphtheria " XBD=1194 XHG=1057 YBD=1181 YHG=1150>toxin.3 " XBD=1321 XHG=1243 YBD=1180 YHG=1149>But

Zilva " XBD=362 XHG=256 YBD=1226 YHG=1196>4 and Agnew " XBD=683 XHG=532 YBD=1226 YHG=1194>found " XBD=785 XHG=698 YBD=1227 YHG=1195>that " XBD=868 XHG=802 YBD=1225 YHG=1194>the " XBD=1043 XHG=885 YBD=1225 YHG=1195>amount " XBD=1100 XHG=1060 YBD=1225 YHG=1194>of " XBD=1277 XHG=1116 YBD=1225 YHG=1194>vitamin " XBD=1322 XHG=1295 YBD=1225 YHG=1193>C" XBD=287 XHG=135 YBD=1279 YHG=1241>present " XBD=340 XHG=300 YBD=1271 YHG=1240>in " XBD=465 XHG=351 YBD=1271 YHG=1239>blood " XBD=547 XHG=477 YBD=1270 YHG=1239>has " XBD=608 XHG=560 YBD=1270 YHG=1249>no " XBD=732 XHG=622 YBD=1270 YHG=1239>effect " XBD=795 XHG=746 YBD=1269 YHG=1248>on " XBD=857 XHG=806 YBD=1269 YHG=1238>its " XBD=1133 XHG=870 YBD=1269 YHG=1238>antibacterial " XBD=1320 XHG=1145 YBD=1277 YHG=1238>activity." XBD=287 XHG=139 YBD=1315 YHG=1283>Similar " XBD=595 XHG=312 YBD=1323 YHG=1283>contradictory " XBD=754 XHG=618 YBD=1314 YHG=1283>results " XBD=877 XHG=778 YBD=1314 YHG=1283>have " XBD=998 XHG=902 YBD=1314 YHG=1282>been " XBD=1203 XHG=1023 YBD=1313 YHG=1282>obtained " XBD=1321 XHG=1227 YBD=1313 YHG=1282>with" XBD=268 XHG=135 YBD=1368 YHG=1328>regard " XBD=325 XHG=284 YBD=1359 YHG=1329>to " XBD=408 XHG=340 YBD=1359 YHG=1328>the " XBD=531 XHG=423 YBD=1359 YHG=1328>other " XBD=850 XHG=545 YBD=1367 YHG=1326>immunological " XBD=995 XHG=865 YBD=1358 YHG=1326>effects " XBD=1049 XHG=1010 YBD=1357 YHG=1326>of " XBD=1129 XHG=1063 YBD=1358 YHG=1323>the " XBD=1318 XHG=1142 YBD=1357 YHG=1326>vitamin." XBD=358 XHG=135 YBD=1412 YHG=1371>Birkhaug,6 " XBD=454 XHG=394 YBD=1402 YHG=1372>for " XBD=677 XHG=491 YBD=1411 YHG=1371>example, " XBD=837 XHG=716 YBD=1402 YHG=1371>found " XBD=963 XHG=875 YBD=1402 YHG=1371>that " XBD=1066 XHG=1001 YBD=1402 YHG=1371>the " XBD=1319 XHG=1105 YBD=1402 YHG=1370>tuberculin" XBD=304 XHG=134 YBD=1447 YHG=1416>reaction " XBD=359 XHG=319 YBD=1446 YHG=1416>in " XBD=616 XHG=374 YBD=1446 YHG=1415>tuberculous " XBD=851 XHG=632 YBD=1455 YHG=1415>guineapigs " XBD=944 XHG=866 YBD=1447 YHG=1425>was " XBD=1073 XHG=960 YBD=1447 YHG=1415>much " XBD=1251 XHG=1088 YBD=1447 YHG=1414>reduced " XBD=1320 XHG=1267 YBD=1454 YHG=1414>by" XBD=201 XHG=135 YBD=1491 YHG=1460>the " XBD=391 XHG=218 YBD=1491 YHG=1459>addition " XBD=448 XHG=409 YBD=1491 YHG=1459>of " XBD=511 XHG=468 YBD=1490 YHG=1461>10 " XBD=603 XHG=529 YBD=1500 YHG=1469>mg. " XBD=645 XHG=622 YBD=1490 YHG=1469>a " XBD=739 XHG=663 YBD=1499 YHG=1459>day " XBD=796 XHG=757 YBD=1490 YHG=1459>of " XBD=975 XHG=812 YBD=1491 YHG=1459>vitamin " XBD=1020 XHG=992 YBD=1491 YHG=1460>C " XBD=1077 XHG=1036 YBD=1491 YHG=1461>to " XBD=1193 XHG=1095 YBD=1491 YHG=1459>their " XBD=1320 XHG=1210 YBD=1490 YHG=1458>usual" XBD=450 XHG=137 YBD=1543 YHG=1503>(non-scorbutic) " XBD=553 XHG=463 YBD=1540 YHG=1504>diet, " XBD=643 XHG=567 YBD=1535 YHG=1503>and " XBD=741 XHG=654 YBD=1535 YHG=1503>that " XBD=829 XHG=753 YBD=1535 YHG=1503>this " XBD=1014 XHG=842 YBD=1535 YHG=1504>addition " XBD=1103 XHG=1025 YBD=1534 YHG=1504>had " XBD=1137 XHG=1114 YBD=1534 YHG=1513>a " XBD=1318 XHG=1149 YBD=1535 YHG=1503>curative" XBD=246 XHG=135 YBD=1579 YHG=1548>effect " XBD=316 XHG=267 YBD=1578 YHG=1557>on " XBD=402 XHG=334 YBD=1579 YHG=1547>the " XBD=576 XHG=422 YBD=1579 YHG=1548>disease. " XBD=747 XHG=630 YBD=1579 YHG=1547>Other " XBD=954 XHG=764 YBD=1579 YHG=1547>workers have " XBD=1212 XHG=1091 YBD=1579 YHG=1547>found " XBD=1318 XHG=1231 YBD=1578 YHG=1547>that" XBD=201 XHG=134 YBD=1623 YHG=1592>the " XBD=378 XHG=220 YBD=1623 YHG=1593>amount " XBD=437 XHG=398 YBD=1623 YHG=1592>of " XBD=617 XHG=454 YBD=1622 YHG=1592>vitamin " XBD=663 XHG=637 YBD=1623 YHG=1592>C " XBD=722 XHG=681 YBD=1623 YHG=1592>in " XBD=806 XHG=740 YBD=1624 YHG=1592>the " XBD=902 XHG=825 YBD=1623 YHG=1592>diet " XBD=1054 XHG=922 YBD=1624 YHG=1592>affects " XBD=1139 XHG=1072 YBD=1623 YHG=1592>the " XBD=1319 XHG=1158 YBD=1631 YHG=1592>comple-" XBD=241 XHG=135 YBD=1667 YHG=1637>ment " XBD=346 XHG=256 YBD=1667 YHG=1636>titre " XBD=401 XHG=362 YBD=1667 YHG=1636>of " XBD=616 XHG=416 YBD=1676 YHG=1635>guineapig " XBD=757 XHG=630 YBD=1667 YHG=1636>blood. " XBD=883 XHG=808 YBD=1667 YHG=1637>Yet " XBD=1002 XHG=899 YBD=1667 YHG=1646>some workers " XBD=1318 XHG=1193 YBD=1667 YHG=1635>have" XBD=255 XHG=134 YBD=1712 YHG=1680>found " XBD=359 XHG=272 YBD=1712 YHG=1679>that " XBD=487 XHG=379 YBD=1711 YHG=1681>extra " XBD=666 XHG=504 YBD=1711 YHG=1680>vitamin " XBD=712 XHG=686 YBD=1711 YHG=1680>C " XBD=820 XHG=732 YBD=1711 YHG=1681>does " XBD=906 XHG=838 YBD=1711 YHG=1682>not " XBD=1130 XHG=926 YBD=1712 YHG=1680>accelerate " XBD=1213 XHG=1147 YBD=1712 YHG=1680>the " XBD=1318 XHG=1232 YBD=1712 YHG=1689>cure" XBD=175 XHG=134 YBD=1756 YHG=1724>of " XBD=444 XHG=195 YBD=1756 YHG=1724>tuberculosis " XBD=499 XHG=459 YBD=1755 YHG=1724>in " XBD=666 XHG=520 YBD=1755 YHG=1724>human " XBD=830 XHG=688 YBD=1765 YHG=1724>beings, " XBD=925 XHG=848 YBD=1755 YHG=1724>and " XBD=1072 XHG=947 YBD=1756 YHG=1725>others " XBD=1187 XHG=1089 YBD=1756 YHG=1725>have " XBD=1317 XHG=1201 YBD=1755 YHG=1724>failed" XBD=175 XHG=133 YBD=1799 YHG=1770>to " XBD=346 XHG=190 YBD=1799 YHG=1767>confirm " XBD=425 XHG=358 YBD=1799 YHG=1768>the " XBD=681 XHG=436 YBD=1808 YHG=1768>relationship " XBD=866 XHG=696 YBD=1800 YHG=1768>between " XBD=1085 XHG=878 YBD=1800 YHG=1769>vitamin-C " XBD=1228 XHG=1098 YBD=1800 YHG=1768>intake " XBD=1317 XHG=1242 YBD=1800 YHG=1769>and" XBD=388 XHG=134 YBD=1851 YHG=1812>complement " XBD=647 XHG=408 YBD=1851 YHG=1812>production. " XBD=777 XHG=698 YBD=1843 YHG=1812>The " XBD=976 XHG=799 YBD=1844 YHG=1813>evidence " XBD=1083 XHG=997 YBD=1844 YHG=1813>that " XBD=1318 XHG=1105 YBD=1850 YHG=1813>infections," XBD=381 XHG=133 YBD=1896 YHG=1856>particularly " XBD=501 XHG=392 YBD=1888 YHG=1856>those " XBD=722 XHG=512 YBD=1897 YHG=1856>producing " XBD=848 XHG=732 YBD=1893 YHG=1856>fever, " XBD=973 XHG=863 YBD=1888 YHG=1866>cause " XBD=1008 XHG=986 YBD=1887 YHG=1866>a " XBD=1094 XHG=1020 YBD=1888 YHG=1857>loss " XBD=1146 XHG=1107 YBD=1888 YHG=1857>of " XBD=1319 XHG=1157 YBD=1889 YHG=1857>vitamin" XBD=162 XHG=136 YBD=1931 YHG=1900>C " XBD=288 XHG=188 YBD=1932 YHG=1900>from " XBD=380 XHG=313 YBD=1931 YHG=1900>the " XBD=509 XHG=407 YBD=1940 YHG=1900>body " XBD=656 XHG=537 YBD=1932 YHG=1910>seems " XBD=973 XHG=692 YBD=1941 YHG=1900>convincing. , " XBD=1126 XHG=997 YBD=1932 YHG=1901>Harris " XBD=1234 XHG=1158 YBD=1932 YHG=1901>and " XBD=1318 XHG=1260 YBD=1933 YHG=1902>his" XBD=341 XHG=134 YBD=1984 YHG=1944>colleagues " XBD=370 XHG=355 YBD=1962 YHG=1944>9 " XBD=510 XHG=390 YBD=1975 YHG=1944>found " XBD=555 XHG=532 YBD=1975 YHG=1953>a " XBD=737 XHG=576 YBD=1976 YHG=1944>lowered " XBD=957 XHG=765 YBD=1976 YHG=1945>excretion " XBD=1018 XHG=979 YBD=1976 YHG=1946>of " XBD=1206 XHG=1045 YBD=1977 YHG=1946>vitamin " XBD=1256 XHG=1230 YBD=1977 YHG=1945>C " XBD=1318 XHG=1278 YBD=1977 YHG=1946>in" XBD=345 XHG=133 YBD=2024 YHG=1988>infections, " XBD=451 XHG=375 YBD=2018 YHG=1988>and " XBD=587 XHG=478 YBD=2019 YHG=1988>when " XBD=681 XHG=615 YBD=2020 YHG=1988>the " XBD=890 XHG=708 YBD=2020 YHG=1988>infection " XBD=994 XHG=917 YBD=2020 YHG=1999>was " XBD=1225 XHG=1030 YBD=2021 YHG=1999>overcome " XBD=1318 XHG=1252 YBD=2021 YHG=1990>the" XBD=341 XHG=133 YBD=2063 YHG=2031>vitamin-C " XBD=561 XHG=369 YBD=2062 YHG=2032>excretion " XBD=743 XHG=588 YBD=2062 YHG=2031>became " XBD=919 XHG=770 YBD=2063 YHG=2032>normal " XBD=1068 XHG=946 YBD=2072 YHG=2033>again. " XBD=1318 XHG=1130 YBD=2073 YHG=2033>Similarly" XBD=200 XHG=133 YBD=2107 YHG=2075>the " XBD=424 XHG=216 YBD=2107 YHG=2075>vitamin-C " XBD=596 XHG=441 YBD=2106 YHG=2077>content " XBD=654 XHG=615 YBD=2106 YHG=2076>of " XBD=736 XHG=670 YBD=2106 YHG=2076>the " XBD=856 XHG=752 YBD=2116 YHG=2075>body " XBD=984 XHG=872 YBD=2107 YHG=2076>fluids " XBD=1069 XHG=1000 YBD=2108 YHG=2076>has " XBD=1181 XHG=1085 YBD=2108 YHG=2077>been " XBD=1316 XHG=1196 YBD=2108 YHG=2077>found" XBD=175 XHG=132 YBD=2150 YHG=2121>to " XBD=237 XHG=190 YBD=2150 YHG=2120>be " XBD=415 XHG=252 YBD=2151 YHG=2120>reduced " XBD=467 XHG=428 YBD=2151 YHG=2120>in " XBD=689 XHG=489 YBD=2151 YHG=2120>infections " XBD=788 XHG=711 YBD=2150 YHG=2120>and " XBD=889 XHG=803 YBD=2151 YHG=2120>that " XBD=947 XHG=908 YBD=2151 YHG=2120>of " XBD=1034 XHG=968 YBD=2151 YHG=2121>the " XBD=1184 XHG=1050 YBD=2161 YHG=2130>organs " XBD=1240 XHG=1200 YBD=2152 YHG=2121>of " XBD=1316 XHG=1254 YBD=2152 YHG=2131>ex-" XBD=400 XHG=133 YBD=2204 YHG=2163>perimentally " XBD=575 XHG=409 YBD=2196 YHG=2164>infected " XBD=744 XHG=585 YBD=2195 YHG=2163>animals " XBD=930 XHG=755 YBD=2195 YHG=2163>likewise. " XBD=1061 XHG=966 YBD=2196 YHG=2164>Hess " XBD=1099 XHG=1070 YBD=2183 YHG=2164>10 " XBD=1187 XHG=1112 YBD=2196 YHG=2165>and " XBD=1319 XHG=1199 YBD=2196 YHG=2165>Fox 11" XBD=232 XHG=133 YBD=2239 YHG=2207>have " XBD=438 XHG=255 YBD=2250 YHG=2207>observed " XBD=549 XHG=461 YBD=2239 YHG=2208>that " XBD=614 XHG=574 YBD=2238 YHG=2207>in " XBD=660 XHG=638 YBD=2238 YHG=2217>a " XBD=821 XHG=685 YBD=2247 YHG=2217>person " XBD=884 XHG=845 YBD=2238 YHG=2208>in " XBD=926 XHG=903 YBD=2238 YHG=2217>a " XBD=1205 XHG=948 YBD=2248 YHG=2208>prescorbutic " XBD=1317 XHG=1231 YBD=2240 YHG=2219>con-" XBD=257 XHG=135 YBD=2283 YHG=2251>dition " XBD=461 XHG=279 YBD=2283 YHG=2251>infection " XBD=508 XHG=477 YBD=2283 YHG=2252>is " XBD=637 XHG=524 YBD=2282 YHG=2251>liable " XBD=700 XHG=659 YBD=2282 YHG=2253>to " XBD=943 XHG=717 YBD=2292 YHG=2251>precipitate " XBD=1123 XHG=960 YBD=2291 YHG=2261>scurvy ; " XBD=1218 XHG=1148 YBD=2283 YHG=2252>but " XBD=1317 XHG=1235 YBD=2284 YHG=2253>Fox" XBD=322 XHG=133 YBD=2327 YHG=2297>mentions " XBD=424 XHG=337 YBD=2327 YHG=2296>that " XBD=539 XHG=441 YBD=2327 YHG=2296>mine " XBD=747 XHG=555 YBD=2327 YHG=2296>labourers " XBD=834 XHG=764 YBD=2326 YHG=2305>can " XBD=948 XHG=850 YBD=2327 YHG=2296>exist " XBD=1003 XHG=963 YBD=2326 YHG=2296>in " XBD=1204 XHG=1019 YBD=2336 YHG=2298>apparent " XBD=1318 XHG=1219 YBD=2337 YHG=2297>good" XBD=264 XHG=132 YBD=2371 YHG=2339>health " XBD=326 XHG=277 YBD=2371 YHG=2350>on " XBD=486 XHG=337 YBD=2372 YHG=2340>intakes " XBD=538 XHG=500 YBD=2371 YHG=2340>of " XBD=712 XHG=551 YBD=2371 YHG=2339>vitamin " XBD=754 XHG=727 YBD=2371 YHG=2339>C " XBD=807 XHG=764 YBD=2371 YHG=2349>so " XBD=891 XHG=818 YBD=2371 YHG=2339>low " XBD=1038 XHG=904 YBD=2378 YHG=2340>(about " XBD=1098 XHG=1055 YBD=2370 YHG=2342>15 " XBD=1185 XHG=1111 YBD=2380 YHG=2350>mg. " XBD=1316 XHG=1198 YBD=2380 YHG=2341>daily)" XBD=176 XHG=134 YBD=2415 YHG=2392>as " XBD=290 XHG=200 YBD=2424 YHG=2385>only " XBD=392 XHG=313 YBD=2424 YHG=2384>just " XBD=457 XHG=416 YBD=2415 YHG=2386>to " XBD=641 XHG=481 YBD=2424 YHG=2385>prevent " XBD=772 XHG=665 YBD=2415 YHG=2384>them " XBD=893 XHG=794 YBD=2415 YHG=2384>from " XBD=1142 XHG=919 YBD=2426 YHG=2384>developing " XBD=1315 XHG=1166 YBD=2424 YHG=2394>scurvy." XBD=244 XHG=135 YBD=2459 YHG=2427>Some " XBD=518 XHG=267 YBD=2468 YHG=2429>experiments " XBD=590 XHG=542 YBD=2459 YHG=2438>on " XBD=678 XHG=612 YBD=2459 YHG=2427>the " XBD=871 XHG=700 YBD=2459 YHG=2428>curative " XBD=1022 XHG=893 YBD=2458 YHG=2427>effects " XBD=1083 XHG=1045 YBD=2458 YHG=2428>of " XBD=1266 XHG=1105 YBD=2459 YHG=2428>vitamin " XBD=1316 XHG=1290 YBD=2460 YHG=2428>C" XBD=172 XHG=133 YBD=2503 YHG=2471>in " XBD=384 XHG=184 YBD=2504 YHG=2472>infections " XBD=435 XHG=395 YBD=2503 YHG=2473>in " XBD=537 XHG=447 YBD=2503 YHG=2481>man " XBD=659 XHG=549 YBD=2503 YHG=2472>claim " XBD=694 XHG=672 YBD=2503 YHG=2481>a " XBD=868 XHG=704 YBD=2512 YHG=2472>positive " XBD=956 XHG=881 YBD=2502 YHG=2472>and " XBD=1095 XHG=969 YBD=2502 YHG=2471>others " XBD=1129 XHG=1108 YBD=2502 YHG=2481>a " XBD=1316 XHG=1140 YBD=2511 YHG=2472>negative" XBD=256 XHG=133 YBD=2548 YHG=2516>effect. " XBD=397 XHG=308 YBD=2548 YHG=2516>This " XBD=443 XHG=411 YBD=2547 YHG=2516>is " XBD=645 XHG=457 YBD=2556 YHG=2515>probably " XBD=733 XHG=660 YBD=2548 YHG=2516>due " XBD=789 XHG=749 YBD=2547 YHG=2518>to " XBD=872 XHG=806 YBD=2547 YHG=2516>the " XBD=1073 XHG=888 YBD=2555 YHG=2515>difficulty " XBD=1129 XHG=1090 YBD=2546 YHG=2515>of " XBD=1317 XHG=1144 YBD=2556 YHG=2516>carrying" XBD=201 XHG=133 YBD=2591 YHG=2562>out " XBD=452 XHG=245 YBD=2593 YHG=2560>controlled " XBD=747 XHG=494 YBD=2600 YHG=2560>experiments " XBD=867 XHG=790 YBD=2590 YHG=2560>and " XBD=948 XHG=909 YBD=2590 YHG=2560>of " XBD=1174 XHG=991 YBD=2599 YHG=2560>assessing " XBD=1315 XHG=1216 YBD=2590 YHG=2569>cure." XBD=292 XHG=132 YBD=2644 YHG=2603>Anyone " XBD=392 XHG=307 YBD=2636 YHG=2605>who " XBD=476 XHG=407 YBD=2636 YHG=2605>has " XBD=583 XHG=493 YBD=2644 YHG=2604>kept " XBD=819 XHG=600 YBD=2644 YHG=2604>guineapigs " XBD=893 XHG=834 YBD=2634 YHG=2604>for " XBD=997 XHG=907 YBD=2644 YHG=2604>long " XBD=1061 XHG=1013 YBD=2634 YHG=2613>on " XBD=1174 XHG=1078 YBD=2634 YHG=2603>diets " XBD=1263 XHG=1190 YBD=2635 YHG=2603>low " XBD=1316 XHG=1276 YBD=2634 YHG=2603>in" XBD=295 XHG=132 YBD=2679 YHG=2649>vitamin " XBD=339 XHG=314 YBD=2679 YHG=2648>C " XBD=432 XHG=355 YBD=2680 YHG=2648>will " XBD=546 XHG=447 YBD=2680 YHG=2648>have " XBD=714 XHG=563 YBD=2679 YHG=2649>noticed " XBD=817 XHG=730 YBD=2679 YHG=2648>that " XBD=927 XHG=834 YBD=2687 YHG=2648>they " XBD=1008 XHG=945 YBD=2679 YHG=2657>are " XBD=1128 XHG=1025 YBD=2678 YHG=2657>more " XBD=1258 XHG=1143 YBD=2687 YHG=2647>likely " XBD=1316 XHG=1274 YBD=2678 YHG=2649>to" XBD=193 XHG=123 YBD=2723 YHG=2692>.die " XBD=302 XHG=203 YBD=2723 YHG=2693>from " XBD=512 XHG=314 YBD=2723 YHG=2692>infections " XBD=620 XHG=524 YBD=2723 YHG=2693>than " XBD=737 XHG=628 YBD=2723 YHG=2692>those " XBD=934 XHG=746 YBD=2732 YHG=2692>receiving " XBD=1130 XHG=943 YBD=2730 YHG=2692>adequate " XBD=1316 XHG=1139 YBD=2721 YHG=2692>amounts" XBD=171 XHG=132 YBD=2766 YHG=2736>of " XBD=275 XHG=209 YBD=2767 YHG=2736>the " XBD=488 XHG=314 YBD=2766 YHG=2736>vitamin. " XBD=720 XHG=538 YBD=2768 YHG=2736>Whether " XBD=808 XHG=759 YBD=2766 YHG=2744>an " XBD=1036 XHG=847 YBD=2775 YHG=2735>adequate " XBD=1233 XHG=1075 YBD=2765 YHG=2735>amount " XBD=1312 XHG=1273 YBD=2766 YHG=2734>of" XBD=294 XHG=131 YBD=2810 YHG=2780>vitamin " XBD=342 XHG=317 YBD=2810 YHG=2779>C " XBD=494 XHG=364 YBD=2811 YHG=2789>means " XBD=728 XHG=515 YBD=2811 YHG=2780>saturation " XBD=841 XHG=747 YBD=2810 YHG=2779>with " XBD=928 XHG=862 YBD=2810 YHG=2779>the " XBD=1112 XHG=949 YBD=2811 YHG=2779>vitamin " XBD=1163 XHG=1131 YBD=2809 YHG=2778>is " XBD=1313 XHG=1184 YBD=2809 YHG=2787>uncer-" XBD=225 XHG=131 YBD=2860 YHG=2824>tain, " XBD=312 XHG=241 YBD=2854 YHG=2824>but " XBD=442 XHG=326 YBD=2854 YHG=2823>Jones " XBD=532 XHG=455 YBD=2854 YHG=2824>and " XBD=601 XHG=544 YBD=2854 YHG=2824>his " XBD=865 XHG=617 YBD=2863 YHG=2824>colleagues 12 " XBD=989 XHG=878 YBD=2854 YHG=2823>claim " XBD=1089 XHG=1002 YBD=2854 YHG=2823>that " XBD=1315 XHG=1103 YBD=2854 YHG=2821>saturation

1. Otani, T. Orient. J. Dis. Infants, 1939, 25, 1.2. Büsing, K. H. Münch. med. Wschr. 1939, 86, 575; Meyer, H. H.

Klin. Wschr. 1939, 20, 704.3. Greenwald, C. K. and Harde, E. Proc. Soc. exp. Biol., N.Y. 1935,

32, 1157.4. Zilva, S. S. Brit. J. exp. Path. 1937, 18, 449.5. Agnew et al. J. Immunol. 1942, 44, 289.6. Birkhaug, K. E. Acta tuberc. scand. 1939, 13, 45.7. Ecker, E. E. and Pilleman, L. J. Amer. med. Ass. 1939, 112,

1449 ; Chu, F. and Chow, B. F, Proc. Soc. exp. Biol., N.Y. 1938,38, 679.

8. Sweany, H. C. et al. J. Amer. med. Ass. 1941, 116, 469.9. Harris, L. J. et al. Lancet, 1937, ii, 183, and other papers.

10. Hess, A. F. Scurvy Past and Present, London, 1920.11. Fox, F. W. J. Lancet, 1943, 63, 349.12. Jones, C. M., Bartlett, M. K., Ryan, A. E. and Drummey, G. D.

New Engl. J. Med. 1943, 229, 642.

" XBD=1491 XHG=1384 YBD=221 YHG=181>helps " XBD=1590 XHG=1550 YBD=212 YHG=183>to " XBD=1799 XHG=1640 YBD=221 YHG=182>prevent " XBD=2119 XHG=1849 YBD=220 YHG=180>experimental " XBD=2305 XHG=2166 YBD=212 YHG=180>wound " XBD=2561 XHG=2352 YBD=212 YHG=180>infections." XBD=1536 XHG=1385 YBD=262 YHG=226>Hunt,13 " XBD=1778 XHG=1586 YBD=257 YHG=225>Bourne 14 " XBD=1889 XHG=1814 YBD=255 YHG=224>and " XBD=2051 XHG=1926 YBD=255 YHG=224>others " XBD=2185 XHG=2086 YBD=256 YHG=224>have " XBD=2506 XHG=2223 YBD=256 YHG=225>demonstrated " XBD=2562 XHG=2541 YBD=257 YHG=234>a" XBD=1617 XHG=1381 YBD=301 YHG=269>retardation " XBD=1676 XHG=1637 YBD=300 YHG=269>of " XBD=1926 XHG=1695 YBD=299 YHG=268>fibroblastic " XBD=2108 XHG=1946 YBD=308 YHG=269>activity " XBD=2165 XHG=2126 YBD=300 YHG=269>in " XBD=2328 XHG=2186 YBD=309 YHG=270>aseptic " XBD=2504 XHG=2347 YBD=300 YHG=269>wounds " XBD=2560 XHG=2523 YBD=300 YHG=269>in" XBD=1570 XHG=1379 YBD=345 YHG=314>scorbutic " XBD=1663 XHG=1586 YBD=344 YHG=314>and " XBD=1937 XHG=1679 YBD=344 YHG=312>subscorbutic " XBD=2126 XHG=1955 YBD=349 YHG=313>animals, " XBD=2219 XHG=2143 YBD=344 YHG=313>and " XBD=2345 XHG=2238 YBD=344 YHG=313>Hunt " XBD=2560 XHG=2363 YBD=353 YHG=313>suggested" XBD=1469 XHG=1382 YBD=388 YHG=358>that " XBD=1503 XHG=1482 YBD=388 YHG=367>a " XBD=1657 XHG=1516 YBD=388 YHG=357>similar " XBD=1785 XHG=1669 YBD=396 YHG=357>study " XBD=1935 XHG=1797 YBD=387 YHG=356>should " XBD=1990 XHG=1944 YBD=387 YHG=356>be " XBD=2112 XHG=2003 YBD=387 YHG=356>made " XBD=2161 XHG=2122 YBD=387 YHG=356>of " XBD=2265 XHG=2168 YBD=388 YHG=356>local " XBD=2559 XHG=2272 YBD=388 YHG=357>inflammation." XBD=1511 XHG=1383 YBD=440 YHG=401>Meyer " XBD=1614 XHG=1538 YBD=431 YHG=401>and " XBD=1808 XHG=1640 YBD=440 YHG=399>Meyer 15 " XBD=1931 XHG=1832 YBD=431 YHG=400>have " XBD=2042 XHG=1957 YBD=431 YHG=410>now " XBD=2271 XHG=2072 YBD=431 YHG=400>examined " XBD=2364 XHG=2297 YBD=431 YHG=401>the " XBD=2500 XHG=2390 YBD=432 YHG=400>effect " XBD=2563 XHG=2525 YBD=432 YHG=402>of" XBD=1591 XHG=1383 YBD=476 YHG=444>vitamin-C " XBD=1822 XHG=1619 YBD=484 YHG=444>deficiency " XBD=1897 XHG=1848 YBD=474 YHG=453>on " XBD=1944 XHG=1922 YBD=474 YHG=453>a " XBD=2066 XHG=1969 YBD=475 YHG=444>local " XBD=2372 XHG=2090 YBD=483 YHG=444>inflammatory " XBD=2562 XHG=2397 YBD=476 YHG=444>reaction" XBD=1575 XHG=1382 YBD=528 YHG=489>produced " XBD=1936 XHG=1586 YBD=528 YHG=488>by staphylococci, " XBD=2062 XHG=1944 YBD=518 YHG=488>under " XBD=2253 XHG=2073 YBD=527 YHG=488>carefully " XBD=2467 XHG=2259 YBD=519 YHG=488>controlled " XBD=2560 XHG=2478 YBD=519 YHG=497>con." XBD=1538 XHG=1384 YBD=568 YHG=533>ditions, " XBD=1670 XHG=1560 YBD=572 YHG=533>using " XBD=1758 XHG=1692 YBD=562 YHG=532>the " XBD=1909 XHG=1777 YBD=571 YHG=532>paired " XBD=2077 XHG=1928 YBD=572 YHG=532>feeding " XBD=2270 XHG=2103 YBD=563 YHG=532>method. " XBD=2403 XHG=2323 YBD=562 YHG=531>One " XBD=2561 XHG=2423 YBD=563 YHG=532>animal" XBD=1423 XHG=1383 YBD=607 YHG=576>of " XBD=1540 XHG=1447 YBD=607 YHG=576>each " XBD=1646 XHG=1564 YBD=615 YHG=576>pair " XBD=1745 XHG=1668 YBD=606 YHG=585>was " XBD=1881 XHG=1769 YBD=615 YHG=575>given " XBD=1949 XHG=1907 YBD=606 YHG=578>15 " XBD=2044 XHG=1970 YBD=615 YHG=584>mg. " XBD=2105 XHG=2066 YBD=606 YHG=576>of " XBD=2289 XHG=2121 YBD=607 YHG=576>vitamin " XBD=2337 XHG=2311 YBD=606 YHG=575>C " XBD=2465 XHG=2363 YBD=615 YHG=575>daily " XBD=2562 XHG=2489 YBD=607 YHG=576>and" XBD=1448 XHG=1382 YBD=650 YHG=620>the " XBD=1575 XHG=1466 YBD=651 YHG=620>other " XBD=1639 XHG=1590 YBD=650 YHG=629>no " XBD=1819 XHG=1656 YBD=651 YHG=619>vitamin " XBD=1875 XHG=1836 YBD=651 YHG=619>C. " XBD=2005 XHG=1926 YBD=650 YHG=619>Ten " XBD=2115 XHG=2022 YBD=659 YHG=620>days " XBD=2231 XHG=2132 YBD=650 YHG=619>after " XBD=2312 XHG=2246 YBD=650 YHG=619>the " XBD=2426 XHG=2329 YBD=650 YHG=620>start " XBD=2561 XHG=2444 YBD=651 YHG=618>of. the" XBD=1630 XHG=1383 YBD=703 YHG=664>experiment, |>" XBD=1713 XHG=1656 YBD=694 YHG=665>0-1 " XBD=1847 XHG=1741 YBD=694 YHG=673>c.cm. " XBD=1912 XHG=1873 YBD=694 YHG=663>of " XBD=1958 XHG=1936 YBD=694 YHG=673>a " XBD=2203 XHG=1983 YBD=703 YHG=664>suspension " XBD=2445 XHG=2228 YBD=703 YHG=663>containing " XBD=2561 XHG=2475 YBD=694 YHG=665>1000" XBD=1527 XHG=1384 YBD=738 YHG=707>million " XBD=1832 XHG=1551 YBD=747 YHG=707>staphylococci " XBD=1922 XHG=1855 YBD=747 YHG=717>per " XBD=2051 XHG=1945 YBD=738 YHG=717>c.cm. " XBD=2152 XHG=2075 YBD=748 YHG=717>was " XBD=2342 XHG=2176 YBD=747 YHG=707>injected " XBD=2447 XHG=2365 YBD=738 YHG=707>into " XBD=2561 XHG=2471 YBD=738 YHG=707>each" XBD=1536 XHG=1383 YBD=782 YHG=751>animal. " XBD=1693 XHG=1587 YBD=782 YHG=751>Pairs " XBD=1747 XHG=1708 YBD=782 YHG=751>of " XBD=1920 XHG=1761 YBD=782 YHG=751>animals " XBD=2030 XHG=1934 YBD=782 YHG=761>were " XBD=2159 XHG=2044 YBD=782 YHG=745>killed " XBD=2220 XHG=2174 YBD=782 YHG=752>24 " XBD=2359 XHG=2233 YBD=787 YHG=751>hours, " XBD=2423 XHG=2378 YBD=781 YHG=751>72 " XBD=2560 XHG=2437 YBD=788 YHG=750>hours," XBD=1405 XHG=1386 YBD=825 YHG=796>8 " XBD=1534 XHG=1428 YBD=834 YHG=795>days, " XBD=1604 XHG=1561 YBD=826 YHG=796>14 " XBD=1718 XHG=1624 YBD=834 YHG=795>days " XBD=1816 XHG=1740 YBD=826 YHG=795>and " XBD=1883 XHG=1841 YBD=826 YHG=797>18 " XBD=1999 XHG=1905 YBD=835 YHG=795>days " XBD=2118 XHG=2019 YBD=826 YHG=795>after " XBD=2380 XHG=2136 YBD=826 YHG=795>inoculation. " XBD=2479 XHG=2432 YBD=825 YHG=794>In " XBD=2561 XHG=2498 YBD=827 YHG=795>the" XBD=1465 XHG=1383 YBD=869 YHG=838>first " XBD=1566 XHG=1488 YBD=870 YHG=841>two " XBD=1740 XHG=1589 YBD=878 YHG=848>groups, " XBD=1983 XHG=1766 YBD=870 YHG=839>differences " XBD=2176 XHG=2007 YBD=870 YHG=839>between " XBD=2265 XHG=2200 YBD=870 YHG=839>the " XBD=2464 XHG=2290 YBD=869 YHG=838>deficient " XBD=2562 XHG=2489 YBD=870 YHG=839>and" XBD=1531 XHG=1383 YBD=913 YHG=882>normal " XBD=1709 XHG=1550 YBD=914 YHG=883>animals " XBD=1823 XHG=1726 YBD=914 YHG=892>were " XBD=1911 XHG=1842 YBD=913 YHG=884>not " XBD=1971 XHG=1931 YBD=914 YHG=892>as " XBD=2073 XHG=1989 YBD=914 YHG=882>well " XBD=2248 XHG=2092 YBD=913 YHG=882>marked " XBD=2308 XHG=2266 YBD=913 YHG=891>as " XBD=2366 XHG=2326 YBD=913 YHG=882>in " XBD=2451 XHG=2385 YBD=912 YHG=882>the " XBD=2563 XHG=2470 YBD=914 YHG=882>later" XBD=1534 XHG=1382 YBD=966 YHG=935>groups, " XBD=1743 XHG=1560 YBD=966 YHG=926>although " XBD=1809 XHG=1767 YBD=957 YHG=928>at " XBD=1880 XHG=1837 YBD=957 YHG=927>72 " XBD=2019 XHG=1904 YBD=957 YHG=927>hours " XBD=2150 XHG=2043 YBD=957 YHG=926>there " XBD=2268 XHG=2173 YBD=957 YHG=936>were " XBD=2397 XHG=2294 YBD=956 YHG=935>more " XBD=2561 XHG=2422 YBD=957 YHG=934>macro-" XBD=1524 XHG=1381 YBD=1010 YHG=969>phages " XBD=1697 XHG=1551 YBD=1001 YHG=970>around " XBD=1789 XHG=1723 YBD=1001 YHG=970>the " XBD=2048 XHG=1815 YBD=1001 YHG=971>inoculation " XBD=2115 XHG=2073 YBD=1001 YHG=971>in " XBD=2208 XHG=2140 YBD=1012 YHG=969>the normal " XBD=2561 XHG=2405 YBD=1002 YHG=969>animals" XBD=1475 XHG=1379 YBD=1044 YHG=1013>than " XBD=1544 XHG=1502 YBD=1044 YHG=1013>in " XBD=1636 XHG=1570 YBD=1045 YHG=1014>the " XBD=1840 XHG=1665 YBD=1045 YHG=1013>deficient " XBD=1970 XHG=1869 YBD=1045 YHG=1024>ones. " XBD=2222 XHG=2020 YBD=1055 YHG=1014>Migration " XBD=2289 XHG=2250 YBD=1044 YHG=1013>of " XBD=2559 XHG=2315 YBD=1054 YHG=1013>polymorphs" XBD=1529 XHG=1380 YBD=1088 YHG=1057>seemed " XBD=1607 XHG=1539 YBD=1089 YHG=1059>not " XBD=1661 XHG=1620 YBD=1089 YHG=1059>to " XBD=1723 XHG=1675 YBD=1089 YHG=1057>be " XBD=1898 XHG=1735 YBD=1091 YHG=1057>affected " XBD=2033 XHG=1910 YBD=1098 YHG=1058>by the " XBD=2261 XHG=2048 YBD=1098 YHG=1058>deficiency, |>" XBD=2455 XHG=2271 YBD=1097 YHG=1057>although " XBD=2559 XHG=2466 YBD=1098 YHG=1058>they" XBD=1531 XHG=1381 YBD=1133 YHG=1102>seemed " XBD=1625 XHG=1553 YBD=1133 YHG=1101>less " XBD=1773 XHG=1648 YBD=1134 YHG=1102>active " XBD=2111 XHG=1794 YBD=1143 YHG=1102>phagocytically. " XBD=2208 XHG=2162 YBD=1133 YHG=1102>In " XBD=2297 XHG=2230 YBD=1133 YHG=1102>the |>" XBD=2416 XHG=2319 YBD=1133 YHG=1102>later " XBD=2560 XHG=2440 YBD=1142 YHG=1104>stages" XBD=1448 XHG=1381 YBD=1176 YHG=1145>the " XBD=1682 XHG=1464 YBD=1177 YHG=1145>differences " XBD=1867 XHG=1698 YBD=1177 YHG=1146>between " XBD=1948 XHG=1882 YBD=1177 YHG=1147>the " XBD=2110 XHG=1962 YBD=1177 YHG=1146>normal " XBD=2201 XHG=2125 YBD=1177 YHG=1146>and " XBD=2389 XHG=2216 YBD=1177 YHG=1146>deficient " XBD=2562 XHG=2406 YBD=1178 YHG=1146>animals" XBD=1537 XHG=1381 YBD=1220 YHG=1189>became " XBD=1654 XHG=1552 YBD=1220 YHG=1199>more " XBD=1841 XHG=1669 YBD=1221 YHG=1189>obvious. " XBD=1981 XHG=1891 YBD=1221 YHG=1190>This " XBD=2144 XHG=1995 YBD=1221 YHG=1190>seemed " XBD=2200 XHG=2158 YBD=1221 YHG=1191>to " XBD=2261 XHG=2214 YBD=1221 YHG=1190>be " XBD=2349 XHG=2276 YBD=1221 YHG=1190>due " XBD=2508 XHG=2365 YBD=1229 YHG=1189>mainly " XBD=2561 XHG=2521 YBD=1222 YHG=1192>to" XBD=1447 XHG=1381 YBD=1264 YHG=1233>the " XBD=1561 XHG=1474 YBD=1265 YHG=1233>lack " XBD=1628 XHG=1588 YBD=1264 YHG=1234>of " XBD=1851 XHG=1653 YBD=1265 YHG=1233>fibroblast " XBD=2053 XHG=1880 YBD=1274 YHG=1234>activity, " XBD=2124 XHG=2083 YBD=1265 YHG=1243>as " XBD=2227 XHG=2150 YBD=1265 YHG=1234>had " XBD=2350 XHG=2255 YBD=1265 YHG=1234>been " XBD=2498 XHG=2376 YBD=1265 YHG=1234>found " XBD=2561 XHG=2522 YBD=1266 YHG=1235>in" XBD=1525 XHG=1381 YBD=1317 YHG=1278>aseptic " XBD=1706 XHG=1535 YBD=1314 YHG=1277>wounds, " XBD=1841 XHG=1717 YBD=1309 YHG=1277>which " XBD=2060 XHG=1853 YBD=1317 YHG=1278>prevented " XBD=2138 XHG=2072 YBD=1308 YHG=1277>the " XBD=2331 XHG=2149 YBD=1309 YHG=1278>infection " XBD=2441 XHG=2340 YBD=1308 YHG=1277>from " XBD=2563 XHG=2453 YBD=1320 YHG=1277>being" XBD=1506 XHG=1382 YBD=1353 YHG=1321>sealed " XBD=1587 XHG=1523 YBD=1353 YHG=1321>off. " XBD=1844 XHG=1641 YBD=1361 YHG=1321>&dquo; Grossly, " XBD=1927 XHG=1861 YBD=1353 YHG=1322>the " XBD=2060 XHG=1943 YBD=1353 YHG=1322>lesion " XBD=2190 XHG=2075 YBD=1353 YHG=1321>failed " XBD=2246 XHG=2205 YBD=1353 YHG=1324>to " XBD=2387 XHG=2263 YBD=1353 YHG=1322>round " XBD=2466 XHG=2402 YBD=1362 YHG=1331>up. " XBD=2561 XHG=2518 YBD=1354 YHG=1322>In" XBD=1447 XHG=1380 YBD=1397 YHG=1366>the " XBD=1609 XHG=1461 YBD=1398 YHG=1366>normal " XBD=1769 XHG=1622 YBD=1397 YHG=1365>control " XBD=1953 XHG=1781 YBD=1402 YHG=1366>animals, " XBD=2034 XHG=1967 YBD=1397 YHG=1365>the " XBD=2195 XHG=2048 YBD=1397 YHG=1366>abscess " XBD=2364 XHG=2209 YBD=1397 YHG=1365>became " XBD=2475 XHG=2377 YBD=1398 YHG=1366>hard " XBD=2562 XHG=2488 YBD=1398 YHG=1367>and" XBD=1625 XHG=1381 YBD=1446 YHG=1409>button-like, " XBD=1811 XHG=1645 YBD=1441 YHG=1410>whereas " XBD=1870 XHG=1830 YBD=1441 YHG=1410>in " XBD=1954 XHG=1889 YBD=1441 YHG=1410>the " XBD=2163 XHG=1974 YBD=1441 YHG=1410>scorbutic " XBD=2341 XHG=2183 YBD=1441 YHG=1410>animals " XBD=2427 XHG=2361 YBD=1441 YHG=1410>the " XBD=2561 XHG=2446 YBD=1442 YHG=1410>lesion" XBD=1573 XHG=1380 YBD=1485 YHG=1454>remained " XBD=1665 XHG=1590 YBD=1485 YHG=1454>soft " XBD=1760 XHG=1684 YBD=1485 YHG=1454>and " XBD=2109 XHG=1776 YBD=1485 YHG=1454>undemarcated.&dquo; " XBD=2250 XHG=2161 YBD=1485 YHG=1454>This " XBD=2372 XHG=2266 YBD=1485 YHG=1454>work " XBD=2561 XHG=2389 YBD=1486 YHG=1454>confirms" XBD=1467 XHG=1380 YBD=1530 YHG=1499>that " XBD=1646 XHG=1483 YBD=1530 YHG=1498>vitamin " XBD=1689 XHG=1662 YBD=1529 YHG=1498>C " XBD=1735 XHG=1704 YBD=1529 YHG=1499>is " XBD=1960 XHG=1750 YBD=1538 YHG=1499>important " XBD=2015 XHG=1975 YBD=1529 YHG=1498>in " XBD=2248 XHG=2031 YBD=1539 YHG=1498>combating " XBD=2313 XHG=2262 YBD=1529 YHG=1507>an " XBD=2508 XHG=2327 YBD=1530 YHG=1498>infection " XBD=2560 XHG=2522 YBD=1530 YHG=1499>in" XBD=1502 XHG=1379 YBD=1574 YHG=1542>which " XBD=1583 XHG=1516 YBD=1573 YHG=1542>the " XBD=1705 XHG=1595 YBD=1582 YHG=1542>rapid " XBD=1945 XHG=1717 YBD=1582 YHG=1542>production " XBD=1998 XHG=1958 YBD=1573 YHG=1543>of " XBD=2151 XHG=2011 YBD=1574 YHG=1542>fibrous " XBD=2281 XHG=2164 YBD=1574 YHG=1542>tissue " XBD=2326 XHG=2294 YBD=1574 YHG=1543>is " XBD=2390 XHG=2340 YBD=1574 YHG=1552>an " XBD=2562 XHG=2402 YBD=1584 YHG=1543>integral" XBD=1467 XHG=1379 YBD=1628 YHG=1588>part " XBD=1524 XHG=1485 YBD=1618 YHG=1587>of " XBD=1607 XHG=1540 YBD=1618 YHG=1586>the " XBD=1758 XHG=1624 YBD=1626 YHG=1586>body’s " XBD=1941 XHG=1776 YBD=1618 YHG=1587>defence. " XBD=2192 XHG=1993 YBD=1627 YHG=1586>Generally " XBD=2389 XHG=2207 YBD=1628 YHG=1586>speaking " XBD=2476 XHG=2405 YBD=1618 YHG=1596>one " XBD=2561 XHG=2492 YBD=1619 YHG=1597>can" XBD=1449 XHG=1381 YBD=1671 YHG=1641>say " XBD=1552 XHG=1464 YBD=1662 YHG=1631>that " XBD=1709 XHG=1568 YBD=1662 YHG=1631>animal " XBD=1988 XHG=1723 YBD=1671 YHG=1631>experiments, " XBD=2043 XHG=2004 YBD=1662 YHG=1631>in " XBD=2180 XHG=2057 YBD=1662 YHG=1631>which " XBD=2384 XHG=2196 YBD=1671 YHG=1631>adequate " XBD=2561 XHG=2399 YBD=1663 YHG=1632>controls" XBD=1451 XHG=1380 YBD=1707 YHG=1685>can " XBD=1521 XHG=1474 YBD=1707 YHG=1675>be " XBD=1758 XHG=1544 YBD=1712 YHG=1675>instituted, " XBD=1934 XHG=1782 YBD=1716 YHG=1677>suggest " XBD=2043 XHG=1956 YBD=1706 YHG=1676>that " XBD=2228 XHG=2067 YBD=1706 YHG=1675>vitamin " XBD=2279 XHG=2252 YBD=1707 YHG=1675>C " XBD=2371 XHG=2301 YBD=1707 YHG=1675>has " XBD=2443 XHG=2393 YBD=1706 YHG=1684>an " XBD=2560 XHG=2466 YBD=1707 YHG=1676>anti-" XBD=1558 XHG=1378 YBD=1751 YHG=1719>infective " XBD=1748 XHG=1574 YBD=1759 YHG=1720>activity, " XBD=1930 XHG=1764 YBD=1751 YHG=1719>whereas " XBD=2089 XHG=1945 YBD=1751 YHG=1720>human " XBD=2369 XHG=2105 YBD=1760 YHG=1720>experiments, " XBD=2426 XHG=2386 YBD=1750 YHG=1719>in " XBD=2561 XHG=2441 YBD=1751 YHG=1719>which" XBD=1568 XHG=1378 YBD=1804 YHG=1765>adequate " XBD=1763 XHG=1600 YBD=1795 YHG=1764>controls " XBD=1859 XHG=1795 YBD=1795 YHG=1773>are " XBD=2027 XHG=1890 YBD=1795 YHG=1764>almost " XBD=2288 XHG=2059 YBD=1803 YHG=1763>impossible, " XBD=2420 XHG=2320 YBD=1795 YHG=1764>have " XBD=2561 XHG=2451 YBD=1804 YHG=1764>given" XBD=1662 XHG=1380 YBD=1848 YHG=1808>contradictory " XBD=1823 XHG=1675 YBD=1839 YHG=1808>results. " XBD=1953 XHG=1873 YBD=1839 YHG=1808>The " XBD=2182 XHG=1967 YBD=1839 YHG=1808>conclusion " XBD=2253 XHG=2194 YBD=1839 YHG=1808>for " XBD=2331 XHG=2265 YBD=1840 YHG=1808>the " XBD=2439 XHG=2345 YBD=1839 YHG=1809>time " XBD=2562 XHG=2451 YBD=1849 YHG=1808>being" XBD=1482 XHG=1378 YBD=1884 YHG=1855>must " XBD=1545 XHG=1498 YBD=1883 YHG=1853>be " XBD=1647 XHG=1561 YBD=1884 YHG=1853>that " XBD=1694 XHG=1663 YBD=1883 YHG=1852>it " XBD=1741 XHG=1710 YBD=1884 YHG=1852>is " XBD=1967 XHG=1757 YBD=1893 YHG=1852>important " XBD=2024 XHG=1982 YBD=1884 YHG=1854>to " XBD=2172 XHG=2040 YBD=1884 YHG=1862>ensure " XBD=2211 XHG=2188 YBD=1883 YHG=1862>a " XBD=2444 XHG=2226 YBD=1884 YHG=1852>reasonable " XBD=2562 XHG=2461 YBD=1892 YHG=1852>daily" XBD=1626 XHG=1375 YBD=1929 YHG=1897>intake-not " XBD=1724 XHG=1651 YBD=1928 YHG=1897>less " XBD=1846 XHG=1750 YBD=1928 YHG=1896>than " XBD=1990 XHG=1872 YBD=1929 YHG=1896>about " XBD=2064 XHG=2010 YBD=1928 YHG=1899>50 " XBD=2256 XHG=2091 YBD=1937 YHG=1897>mg.-of " XBD=2444 XHG=2281 YBD=1928 YHG=1896>vitamin " XBD=2498 XHG=2472 YBD=1928 YHG=1896>C " XBD=2561 XHG=2523 YBD=1928 YHG=1897>in" XBD=1545 XHG=1378 YBD=1973 YHG=1941>infected " XBD=1701 XHG=1558 YBD=1973 YHG=1941>human " XBD=1858 XHG=1716 YBD=1982 YHG=1941>beings, " XBD=1950 XHG=1874 YBD=1972 YHG=1942>and " XBD=2051 XHG=1964 YBD=1972 YHG=1941>that " XBD=2096 XHG=2065 YBD=1972 YHG=1941>it " XBD=2202 XHG=2112 YBD=1981 YHG=1951>may " XBD=2262 XHG=2215 YBD=1972 YHG=1941>be " XBD=2360 XHG=2276 YBD=1972 YHG=1941>well " XBD=2414 XHG=2373 YBD=1972 YHG=1943>to " XBD=2561 XHG=2429 YBD=1972 YHG=1950>ensure" XBD=1591 XHG=1378 YBD=2017 YHG=1986>saturation " XBD=1644 XHG=1605 YBD=2017 YHG=1986>in " XBD=1710 XHG=1660 YBD=2016 YHG=1985>all " XBD=1886 XHG=1723 YBD=2016 YHG=1985>feverish " XBD=2080 XHG=1900 YBD=2025 YHG=1985>patients." XBD=1598 XHG=1428 YBD=2061 YHG=2029>Vitamin " XBD=1647 XHG=1621 YBD=2060 YHG=2029>C " XBD=1760 XHG=1670 YBD=2068 YHG=2039>may " XBD=1879 XHG=1780 YBD=2060 YHG=2029>have " XBD=1951 XHG=1901 YBD=2060 YHG=2039>an " XBD=2250 XHG=1973 YBD=2060 YHG=2029>anti-infective " XBD=2400 XHG=2272 YBD=2061 YHG=2029>action " XBD=2463 XHG=2422 YBD=2060 YHG=2030>at " XBD=2560 XHG=2485 YBD=2060 YHG=2030>two" XBD=1505 XHG=1378 YBD=2104 YHG=2073>levels. " XBD=1607 XHG=1556 YBD=2104 YHG=2073>At " XBD=1693 XHG=1623 YBD=2104 YHG=2083>one " XBD=1737 XHG=1707 YBD=2104 YHG=2073>it " XBD=1944 XHG=1751 YBD=2104 YHG=2073>functions " XBD=1997 XHG=1957 YBD=2104 YHG=2073>in " XBD=2121 XHG=2012 YBD=2104 YHG=2073>small " XBD=2311 XHG=2134 YBD=2104 YHG=2075>amounts " XBD=2364 XHG=2324 YBD=2104 YHG=2073>in " XBD=2445 XHG=2376 YBD=2104 YHG=2073>the " XBD=2597 XHG=2458 YBD=2112 YHG=2072>body" XBD=1418 XHG=1378 YBD=2148 YHG=2118>in " XBD=1507 XHG=1441 YBD=2149 YHG=2118>the " XBD=1641 XHG=1531 YBD=2149 YHG=2117>usual " XBD=1748 XHG=1662 YBD=2157 YHG=2126>way " XBD=1812 XHG=1771 YBD=2148 YHG=2126>as " XBD=1860 XHG=1837 YBD=2148 YHG=2126>a " XBD=2046 XHG=1882 YBD=2148 YHG=2117>vitamin " XBD=2146 XHG=2070 YBD=2148 YHG=2117>and " XBD=2210 XHG=2169 YBD=2148 YHG=2119>at " XBD=2394 XHG=2234 YBD=2149 YHG=2117>another " XBD=2448 XHG=2415 YBD=2148 YHG=2117>it " XBD=2561 XHG=2473 YBD=2156 YHG=2125>may" XBD=1552 XHG=1376 YBD=2193 YHG=2162>function " XBD=1606 XHG=1567 YBD=2193 YHG=2162>in " XBD=1715 XHG=1622 YBD=2202 YHG=2171>very " XBD=1832 XHG=1730 YBD=2202 YHG=2162>large " XBD=2025 XHG=1848 YBD=2193 YHG=2163>amounts " XBD=2140 XHG=2043 YBD=2201 YHG=2163>(e.g., |>" XBD=2263 XHG=2159 YBD=2192 YHG=2162>0-5-1 " XBD=2317 XHG=2281 YBD=2201 YHG=2170>g. " XBD=2358 XHG=2334 YBD=2192 YHG=2170>a " XBD=2465 XHG=2374 YBD=2201 YHG=2161>day) " XBD=2524 XHG=2483 YBD=2192 YHG=2170>as " XBD=2562 XHG=2538 YBD=2191 YHG=2169>a|>" XBD=1571 XHG=1380 YBD=2246 YHG=2205>drug. A " XBD=1801 XHG=1583 YBD=2246 YHG=2205>large-scale " XBD=2047 XHG=1814 YBD=2246 YHG=2205>experiment " XBD=2102 XHG=2061 YBD=2236 YHG=2207>to " XBD=2192 XHG=2116 YBD=2236 YHG=2207>test " XBD=2271 XHG=2205 YBD=2236 YHG=2205>the " XBD=2397 XHG=2284 YBD=2237 YHG=2205>effect " XBD=2449 XHG=2410 YBD=2236 YHG=2205>of " XBD=2561 XHG=2461 YBD=2245 YHG=2205>large" XBD=1488 XHG=1380 YBD=2281 YHG=2249>doses " XBD=1544 XHG=1504 YBD=2280 YHG=2250>of " XBD=1625 XHG=1559 YBD=2281 YHG=2250>the " XBD=1803 XHG=1640 YBD=2282 YHG=2250>vitamin " XBD=1859 XHG=1819 YBD=2281 YHG=2250>in " XBD=2050 XHG=1874 YBD=2289 YHG=2249>aborting " XBD=2107 XHG=2066 YBD=2280 YHG=2259>or " XBD=2301 XHG=2122 YBD=2289 YHG=2248>reducing " XBD=2382 XHG=2316 YBD=2280 YHG=2249>the " XBD=2562 XHG=2398 YBD=2288 YHG=2249>severity" XBD=1431 XHG=1379 YBD=2330 YHG=2294>of, " XBD=1538 XHG=1457 YBD=2333 YHG=2303>say, " XBD=1668 XHG=1564 YBD=2325 YHG=2294>colds " XBD=1769 XHG=1693 YBD=2325 YHG=2294>and " XBD=1980 XHG=1793 YBD=2325 YHG=2293>influenza " XBD=2126 XHG=2006 YBD=2333 YHG=2293>might " XBD=2316 XHG=2151 YBD=2333 YHG=2293>produce " XBD=2562 XHG=2339 YBD=2332 YHG=2293>interesting" XBD=1526 XHG=1376 YBD=2369 YHG=2337>results.

MINISTER ON EVACUATION SCHEME

" XBD=1494 XHG=1424 YBD=2502 YHG=2473>Mr. |>" XBD=1711 XHG=1513 YBD=2508 YHG=2474>WILLINK, " XBD=1930 XHG=1729 YBD=2510 YHG=2473>reviewing " XBD=1996 XHG=1946 YBD=2503 YHG=2482>on " XBD=2180 XHG=2012 YBD=2510 YHG=2473>Monday " XBD=2261 XHG=2196 YBD=2502 YHG=2473>the " XBD=2360 XHG=2277 YBD=2502 YHG=2473>first " XBD=2563 XHG=2376 YBD=2510 YHG=2473>fortnight" XBD=1420 XHG=1376 YBD=2540 YHG=2512>of " XBD=1501 XHG=1442 YBD=2542 YHG=2512>his " XBD=1755 XHG=1528 YBD=2542 YHG=2513>evacuation " XBD=1942 XHG=1781 YBD=2547 YHG=2513>scheme, " XBD=2042 XHG=1970 YBD=2549 YHG=2513>put " XBD=2134 XHG=2069 YBD=2541 YHG=2513>the " XBD=2277 XHG=2161 YBD=2549 YHG=2512>figure " XBD=2355 XHG=2312 YBD=2541 YHG=2513>at " XBD=2560 XHG=2393 YBD=2547 YHG=2512>152,652." XBD=1453 XHG=1375 YBD=2580 YHG=2551>and " XBD=1633 XHG=1482 YBD=2588 YHG=2550>rapidly " XBD=1774 XHG=1662 YBD=2588 YHG=2552>going " XBD=1867 XHG=1802 YBD=2588 YHG=2548>up. " XBD=2038 XHG=1918 YBD=2581 YHG=2551>Block " XBD=2287 XHG=2066 YBD=2581 YHG=2551>allocations " XBD=2376 XHG=2316 YBD=2580 YHG=2551>for " XBD=2560 XHG=2408 YBD=2585 YHG=2551>100,000" XBD=1537 XHG=1377 YBD=2619 YHG=2589>London " XBD=1708 XHG=1561 YBD=2620 YHG=2600>women " XBD=1814 XHG=1736 YBD=2620 YHG=2590>and " XBD=2007 XHG=1840 YBD=2620 YHG=2590>children " XBD=2109 XHG=2031 YBD=2619 YHG=2590>had " XBD=2229 XHG=2133 YBD=2619 YHG=2590>been " XBD=2368 XHG=2256 YBD=2619 YHG=2589>made " XBD=2490 XHG=2400 YBD=2627 YHG=2590>long " XBD=2562 XHG=2522 YBD=2619 YHG=2590>in" XBD=1560 XHG=1376 YBD=2663 YHG=2629>advance, " XBD=1665 XHG=1588 YBD=2658 YHG=2629>and " XBD=1755 XHG=1696 YBD=2658 YHG=2630>for " XBD=1853 XHG=1786 YBD=2659 YHG=2630>the " XBD=1982 XHG=1881 YBD=2659 YHG=2631>most " XBD=2097 XHG=2010 YBD=2665 YHG=2630>part " XBD=2203 XHG=2127 YBD=2659 YHG=2629>had " XBD=2326 XHG=2232 YBD=2666 YHG=2638>gone " XBD=2558 XHG=2356 YBD=2665 YHG=2629>smoothly." XBD=1455 XHG=1376 YBD=2696 YHG=2668>Not " XBD=1573 XHG=1469 YBD=2696 YHG=2676>more " XBD=1691 XHG=1595 YBD=2697 YHG=2668>than " XBD=1808 XHG=1710 YBD=2705 YHG=2669>0-1% " XBD=1869 XHG=1825 YBD=2698 YHG=2669>of " XBD=1947 XHG=1881 YBD=2697 YHG=2668>the " XBD=2139 XHG=1960 YBD=2699 YHG=2677>evacuees " XBD=2263 XHG=2160 YBD=2697 YHG=2677>came " XBD=2388 XHG=2274 YBD=2704 YHG=2668>back, " XBD=2442 XHG=2401 YBD=2696 YHG=2668>in " XBD=2559 XHG=2456 YBD=2697 YHG=2676>some" XBD=1479 XHG=1374 YBD=2735 YHG=2715>cases " XBD=1665 XHG=1506 YBD=2736 YHG=2706>because " XBD=1795 XHG=1695 YBD=2743 YHG=2707>large " XBD=1968 XHG=1825 YBD=2742 YHG=2707>parties " XBD=2146 XHG=1996 YBD=2736 YHG=2706>refused " XBD=2216 XHG=2174 YBD=2736 YHG=2708>to " XBD=2292 XHG=2245 YBD=2735 YHG=2707>be " XBD=2466 XHG=2321 YBD=2735 YHG=2705>broken " XBD=2558 XHG=2493 YBD=2743 YHG=2715>up." XBD=1616 XHG=1378 YBD=2781 YHG=2744>Hospitality " XBD=1680 XHG=1640 YBD=2773 YHG=2745>in " XBD=1772 XHG=1705 YBD=2775 YHG=2746>the " XBD=1866 XHG=1797 YBD=2774 YHG=2745>NE " XBD=2021 XHG=1892 YBD=2782 YHG=2745>region " XBD=2121 XHG=2044 YBD=2775 YHG=2754>was " XBD=2389 XHG=2147 YBD=2782 YHG=2745>exemplary ; " XBD=2470 XHG=2429 YBD=2773 YHG=2745>in " XBD=2560 XHG=2494 YBD=2775 YHG=2746>the|>" XBD=1462 XHG=1377 YBD=2813 YHG=2784>NW " XBD=1541 XHG=1474 YBD=2813 YHG=2783>the " XBD=1768 XHG=1554 YBD=2813 YHG=2783>time-clash " XBD=1875 XHG=1780 YBD=2814 YHG=2785>with " XBD=1910 XHG=1891 YBD=2797 YHG=2785>&dquo; " XBD=2052 XHG=1928 YBD=2814 YHG=2785>wakes " XBD=2090 XHG=2069 YBD=2797 YHG=2784>&dquo; " XBD=2182 XHG=2104 YBD=2815 YHG=2784>had " XBD=2306 XHG=2194 YBD=2814 YHG=2783>made " XBD=2447 XHG=2319 YBD=2821 YHG=2784>things " XBD=2564 XHG=2459 YBD=2814 YHG=2793>more" XBD=1551 XHG=1377 YBD=2857 YHG=2822>difficult, " XBD=1636 XHG=1565 YBD=2852 YHG=2822>but " XBD=1827 XHG=1655 YBD=2859 YHG=2822>billeting " XBD=2067 XHG=1845 YBD=2853 YHG=2824>authorities " XBD=2163 XHG=2086 YBD=2853 YHG=2824>had " XBD=2305 XHG=2182 YBD=2860 YHG=2824>rarely " XBD=2365 XHG=2323 YBD=2852 YHG=2824>to " XBD=2450 XHG=2384 YBD=2853 YHG=2832>use " XBD=2565 XHG=2465 YBD=2853 YHG=2824>their" XBD=1520 XHG=1376 YBD=2898 YHG=2870>powers " XBD=1582 XHG=1538 YBD=2890 YHG=2861>of " XBD=1838 XHG=1594 YBD=2898 YHG=2862>compulsion. " XBD=1926 XHG=1878 YBD=2897 YHG=2863>(A " XBD=2034 XHG=1936 YBD=2892 YHG=2863>little " XBD=2307 XHG=2050 YBD=2899 YHG=2862>black-listing " XBD=2362 XHG=2321 YBD=2891 YHG=2862>in " XBD=2443 XHG=2377 YBD=2892 YHG=2862>the " XBD=2564 XHG=2460 YBD=2899 YHG=2862>daily" XBD=1480 XHG=1376 YBD=2937 YHG=2909>press " XBD=1590 XHG=1499 YBD=2936 YHG=2909>may " XBD=1703 XHG=1604 YBD=2930 YHG=2900>have " XBD=1866 XHG=1722 YBD=2937 YHG=2901>proved " XBD=2063 XHG=1880 YBD=2937 YHG=2901>salutary, " XBD=2112 XHG=2077 YBD=2931 YHG=2901>if " XBD=2355 XHG=2126 YBD=2938 YHG=2900>wounding.) " XBD=2466 XHG=2406 YBD=2931 YHG=2901>He " XBD=2563 XHG=2485 YBD=2930 YHG=2899>had" XBD=1400 XHG=1377 YBD=2968 YHG=2948>a " XBD=1522 XHG=1418 YBD=2968 YHG=2939>word " XBD=1584 XHG=1540 YBD=2968 YHG=2938>of " XBD=1718 XHG=1596 YBD=2975 YHG=2939>praise " XBD=1794 XHG=1735 YBD=2968 YHG=2939>for " XBD=2006 XHG=1811 YBD=2976 YHG=2940>transport " XBD=2099 XHG=2022 YBD=2968 YHG=2940>and " XBD=2264 XHG=2115 YBD=2976 YHG=2939>feeding " XBD=2563 XHG=2281 YBD=2977 YHG=2941>arrangements" XBD=1417 XHG=1375 YBD=3007 YHG=2978>in " XBD=1508 XHG=1442 YBD=3007 YHG=2978>the " XBD=1700 XHG=1534 YBD=3007 YHG=2978>bombed " XBD=1844 XHG=1725 YBD=3013 YHG=2987>areas, " XBD=1947 XHG=1871 YBD=3007 YHG=2978>and " XBD=2173 XHG=1973 YBD=3015 YHG=2978>especially " XBD=2257 XHG=2197 YBD=3007 YHG=2979>for " XBD=2564 XHG=2281 YBD=3015 YHG=2979>inter-hospital" XBD=1583 XHG=1376 YBD=3053 YHG=3017>transport. " XBD=1713 XHG=1635 YBD=3046 YHG=3017>The " XBD=1859 XHG=1734 YBD=3053 YHG=3017>Royal " XBD=1971 XHG=1879 YBD=3046 YHG=3017>Free " XBD=2182 XHG=1992 YBD=3053 YHG=3017>Hospital, " XBD=2261 XHG=2201 YBD=3046 YHG=3017>for " XBD=2464 XHG=2281 YBD=3054 YHG=3017>example, " XBD=2562 XHG=2485 YBD=3047 YHG=3017>had" XBD=1472 XHG=1376 YBD=3085 YHG=3056>been " XBD=1665 XHG=1497 YBD=3091 YHG=3055>emptied " XBD=1735 XHG=1692 YBD=3084 YHG=3055>of " XBD=1924 XHG=1756 YBD=3092 YHG=3056>patients " XBD=1990 XHG=1949 YBD=3084 YHG=3056>in " XBD=2060 XHG=2016 YBD=3084 YHG=3055>80 " XBD=2251 XHG=2086 YBD=3085 YHG=3056>minutes " XBD=2376 XHG=2276 YBD=3085 YHG=3056>after " XBD=2451 XHG=2400 YBD=3086 YHG=3057>its " XBD=2562 XHG=2476 YBD=3085 YHG=3057>mis-" XBD=1538 XHG=1373 YBD=3123 YHG=3094>fortune.

13. Hunt, A. H. Brit. J. Surg. 1941, 28, 436.14. Bourne, G. H. Lancet, 1942, ii, 661; Ibid, 1944, i, 688.15. Meyer, E. and Meyer, E. B. Bull. Johns Hopk. Hosp. 1944, 74, 98.

" XBD=1553 XHG=1420 YBD=3372 YHG=3340>LIQUID " XBD=1708 XHG=1571 YBD=3367 YHG=3341>extract " XBD=1794 XHG=1723 YBD=3365 YHG=3338>and " XBD=1961 XHG=1808 YBD=3366 YHG=3338>tincture " XBD=2018 XHG=1977 YBD=3366 YHG=3338>of " XBD=2263 XHG=2028 YBD=3374 YHG=3337>ipecacuanha " XBD=2369 XHG=2278 YBD=3366 YHG=3338>have " XBD=2463 XHG=2384 YBD=3366 YHG=3347>now " XBD=2565 XHG=2477 YBD=3365 YHG=3338>been" XBD=1495 XHG=1373 YBD=3415 YHG=3378>placed " XBD=1571 XHG=1525 YBD=3405 YHG=3387>on " XBD=1661 XHG=1599 YBD=3405 YHG=3377>the " XBD=2039 XHG=1691 YBD=3405 YHG=3376>scarce-substances’ " XBD=2242 XHG=2069 YBD=3410 YHG=3377>schedule, " XBD=2334 XHG=2272 YBD=3405 YHG=3377>the " XBD=2566 XHG=2363 YBD=3406 YHG=3375>authorised" XBD=1581 XHG=1371 YBD=3446 YHG=3417>alternative " XBD=1704 XHG=1601 YBD=3454 YHG=3416>being " XBD=1833 XHG=1721 YBD=3453 YHG=3416>liquid " XBD=1988 XHG=1851 YBD=3445 YHG=3419>extract " XBD=2047 XHG=2008 YBD=3444 YHG=3416>of " XBD=2192 XHG=2061 YBD=3455 YHG=3416>squills.


Recommended