Mycobacteria
Acid fast ,aerobic bacilli
M TB obligate intracel parasite stains with Acid Fast so
named AFB
Fast in retaining of carbol fuchsin or fluorochrome dyes
after washing with acid or alcohol or both
Ziehl nielson stain
Cell wall contains complex lipids and glycolipids cord
factor produces granulomas
Multiply in phagocytic cells
Characteristic lesion granuloma with central caseation
and Langhans giant cells
TRANSMITION:PERSON TO PERSON BY INFECTIVE DROPLETS FROM RESPIRATORY SECRETIONS FROM AN ADULT WITH CAVITARY PULM TB COUGHING CROWDED ROOMS INGESTION LESS LIKELY
TUBERCULIN SKIN TEST ALTHOUGH NEGATIVE IN 5-20%
The biologically active material in the liquid medium
after growth of M TB named tuberculin after Koch
A purified protein derivative of tuberculin was made
(PPD)
Mantoux TEST tuberculin units injected intracutaneously