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TUES 4/30 wk-6 OBJECTIVE: 11 TOPIC: genetic technology DO NOW : daily grade: -12.4 READ-APP/Qs...

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TUES 4/30 wk-6 OBJECTIVE: 11 TOPIC: genetic technology DO NOW: daily grade: -12.4 READ-APP/Qs AGENDA: WRAP UP: DW: -13.2 pre-LAB: VIRTUAL ELECTROPHORESIS DUE: BLOCK 12.3 mini-EXAM—this FRI! -WK#5 OBJECTIVE QUIZ—MON (abs: before/after school) -12.3 REVIEW -13.2 READ Qs -13.2 PRE-LAB: ELECTROPHORESIS MON: -GATTACA Qs -wk #5 org/OBJ QUIZ ABSENT-- HANDOUTS: -13.2 virtual electrophoresis -protein concept map COMPLETE & TURN IN: -GATTACA Qs -wk #5 ORG/OBJ QUIZ BEFORE/AFTER SCHOOL : -DW check—12 materials - -protein concept map A:-see next slide general/ honors
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TUES 4/30 wk-6 OBJECTIVE: 11 TOPIC: genetic technology

DO NOW:daily grade: -12.4 READ-APP/Qs

AGENDA:

WRAP UP:DW: -13.2 pre-LAB: VIRTUAL ELECTROPHORESIS DUE:

BLOCK 12.3 mini-EXAM—this FRI!

-WK#5 OBJECTIVE QUIZ—MON (abs: before/after school)-12.3 REVIEW-13.2 READ Qs-13.2 PRE-LAB: ELECTROPHORESIS

MON:-GATTACA Qs-wk #5 org/OBJ QUIZ

ABSENT--HANDOUTS:-13.2 virtual electrophoresis-protein concept map

COMPLETE & TURN IN:-GATTACA Qs-wk #5 ORG/OBJ QUIZBEFORE/AFTER SCHOOL:-DW check—12 materials

-

-protein concept map

A:-see next slide

general/honors

DO NOW

DO NOW

TRANSCRIPTION TRANSLATION

mRNA

CYTOPLASM

NUCLEUS

CYTOPLASM

PROTEINS

AMINO ACIDS

2007-2008

FLOW CHART

TRANSCRIPTION/TRANSLATIONhttp://www.youtube.com/watch?feature=player_embedded&v=NJxobgkPEAoFrom RNA to Protein Synthesis - YouTube

NUCLEUSCYTOPLASMRIBOSOMEDNAmRNArRNAtRNARNA polymeraseAmino AcidPolypeptide chain [PROTEIN]TRANSLATIONTRANSCRIPTION

FLOW CARTTRANSCRIPTION TRANSLATION

-----------------------------

NUCLEUS CYTOPLASM

RNA

polymerase

mRNA [code]

tRNA [interpret]

polypeptide chain / PROTEIN

rRNA

a.a

TRANSCRIPTION/TRANSLATION

PROTEIN

PROTEIN STRUCTURE

12.4 GENE REGULATIONS and MUTATIONS

WHAT YOU WILL LEARN-prokaryotic/eukaryotic gene regulation-types of mutations & results-mutagens

READING Q’s

1-Like DNA code, the following sentence: “The dog ran” contains only 3 letter words

-INSERT a “z” after “Th”—rewrite the sentence:Thz edo gra-WRITE the sentence again inserting an additional letterThz zed ogr-What happens to the sentences as you add letters?become nonsense

READING Q’s

2-DESCRIBE point mutation

-single nucleotide/base pair is changedcan cause a genetic disorder

READING Q’s

3-NAME-what type of mutation occurs when a STOP codon replaces an amino acid codon

-nonsense mutation cause translation to terminate early proteins cannot function normally

READING Q’s

4-EVALUATE-Would a 3-nucleotide insertion result in a frameshift? YES NO-EXPLAIN-insertion of a nucleotide shifts an entire 3 code sequence—shifts amino acid sequence

X

READING Q’s

5-RECORDThe mRNA sequence/sub A for G

-AUG–AAG–UUU–GGC – ACA – UUG-UAA

READING Q’s

6-COMPLETE table: frameshift / substitution

-substitution-substitution-frameshift

READING Q’s

7-EXPLAIN how UV light damages DNA

-links thymines—forms a “kink”

READING Q’s

8-DETERMINE -what a mutation can do to a body (somatic) cell

-cell death-cancer cell

READING Q’s

9-DISCUSS why a mutagen can have longer lasting effects in a sex cell than a body cell

-mutations in sex cells are passed on to their offspring-mutations in body cells are not inherited


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