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UCD DCRC - University College Dublin Symposium Programme.pdf · 15:00 – 15:30 Maciej Tomaszewski,...

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UCD DCRC Complications of Diabetes and Obesity Symposium January 11-13 2017 Initiation, Progression and Regression Sponsored By Science Foundation Ireland Catalyst Award UCD School of Medicine UCD Conway Institute of Biomolecular & Biomedical Research
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UCD DCRC Complications of Diabetes and Obesity Symposium January 11-13 2017

Initiation, Progression and Regression

Sponsored By Science Foundation Ireland Catalyst Award

UCD School of Medicine

UCD Conway Institute of Biomolecular & Biomedical Research

Day 1: 11th January UCD Conway Institute13:00 – 13:50 Registration & Lunch

13:50 - 14:00 WELCOME Catherine Godson

14:00 – 14:30 SESSION 1:INITIATION Chaired by Peter Maxwell QUB & Yvonne O’Meara MMUH

Guy Rutter, Imperial College LondonBeta cell identity in health and in type 2 diabetes: from GWAS to optogenetics

14:30 – 15:00 Ronit Shiri-Sverdlov, MaastrichtOxLDL is taking the lead in NASH

15:00 – 15:30 Maciej Tomaszewski, University of ManchesterGenes of hypertension – insights from the transcriptome profiling of the human kidney

15:30 – 16:00 Amy Jayne McKnight, Queen’s University BelfastGenomic Biomarkers for DKD

16:00 – 16:30 Helen Roche, DCRC University College DublinNutrient derived metabolic-inflammatory stressors on adipogenesis and insulin resistance

16:30 – 17:00 COFFEE BREAK

17:00 – 18:00 Ciaran Duffy, National Contact Point EU Health Horizon 2020 – Opportunities for Funding

19:15 – 22:00 Speaker’s Dinner

UCD DCRC Complications of Diabetes and Obesity Symposium January 11-13 2017Initiation, Progression and Regression

Day 2: 12th January UCD Conway Institute 9:00 – 09:25 SESSION 2:

INITIATIONChaired by Fiona McGillicuddy UCD & Gareth McKay QUB

Ulf Smith, University of Goteborg Regulation of beige/brown adipogenesis by BMP agonists and antagonists

09:25 – 09:50 Lydia Lynch, Harvard Medical School/Trinity College DublinThe role of immune suppression in obesity-induced cancer and infection in humans

09:50 – 10:15 Silke Ryan, University College DublinIntermittent hypoxia-induced adipose tissue inflammation in obstructive sleep apnoea

10:15 – 10:40 Andrew Morris, University of LiverpoolProgress in understanding the genetics of type 2 diabetes

10:40 – 10:55 Eoin Brennan, DCRC University College DublinTherapeutic Potential of Lipoxins in Diabetic Complications

10:55 – 11:15 COFFEE BREAK

11:15 – 11:40 SESSION 3:PROGRESSIONChaired by Carel le Roux UCD & Andy Hogan SVUH

Marta Ruiz-Oretga, Universidad Autonoma de Madrid Epigenetic mechanisms involved in renal diseases: BET inhibitors as potential therapeutic targets.

11:40 – 12:05 Robert Unwin, University College London/Astra Zeneca Goteborg ThePharmaceutical Industry: What is it good for?! A future for drug discovery in nephrology?

12:05 – 12:30 Francisco Lopez-Hernandez, University of SalamancaPathophysiology of diabetic nephropathy and associated biomarkers

12:30 – 12:55 Harald Mischak, Mosaique Munich /University of Glasgow Urinary proteomics in the management of diabetes-associated complications: from discovery to application

12:55 – 13:10 Danny Crean, DCRC University College DublinDesign and characterisation of novel BMP agonists and antagonists for the treatment of fibrotic disease

13:10 – 13:25 Derek Brazil, Queen’s University BelfastGremlins in kidney development and disease

13:25 – 14:00 LUNCH

14:15 – 14:40 SESSION 4:PROGRESSIONChaired by Neil Docherty UCD & John Holian SVUH

Dieter Steinhilber University of FrankfurtRegulation of 5-lipoxygenase in the onset and resolution of inflammation

14:40 – 15:05 Paola Patrignani University of ChietiBiology and inhibition of cyclooxygenases in cardiovascular disease

15:05 – 15:30 Jussi Pihlajamaki University of Eastern Finland Diet, lipids and epigenetics - the role of the human liver

15:30 – 15:55 Lena Carlsson University of GoteborgBariatric surgery and long-term prevention of microvascular complications

15:55 – 16:10 Orina Belton, DCRC University College DublinCardioprotective mechanisms of GLP-1

16:10 – 16:30 COFFEE BREAK

16:30 – 17:15 Maire Coyle UCD Research Office, Marie Curie Training Networks

17:30 – 19:00 Symposium ReceptionCharles Institute

Day 3: 13th January UCD Conway Institute08:30 – 08:55 SESSION 5:

REPAIR & REGENERATIONChaired by Breandan Kennedy UCD & Denise Sadlier MMUH

Mario Schiffer, University of Hannover Regeneration of the actin cytoskeleton in podocytes

08:55 – 09:20 Geltrude Mingrone, Catholic University of Rome New insight into the mechanisms of action of metabolic surgery in diabetes remission

09:20 – 09:45 Alan Stitt, Queen’s University Belfast New therapeutic strategies to treat diabetic retinopathy

09:45 – 10:10 Roel Goldschmeding, University of Utrecht Involvement of DNA damage response in diabetic kidney disease

10:10 – 10:25 Neil Docherty, DCRC University College DublinGastric Bypass and “Medical Bypass”-Impact on Experimental Diabetic Kidney Disease

10:25 – 10:40 John Crean, DCRC University College Dublin Manipulation of the chromatin landscape for therapeutic reprogramming in Diabetic Nephropathy

10:40 – 11:00 COFFEE BREAK

11:00 – 11:45 Facilitated Workshop 1

11:45 – 12:30 Facilitated Workshop 2

12:30 – 13:15 Conclusions and Future Plans

13:15 LUNCH

14:00 Adjourn

CONTACT DETAILS:

School Office, UCD School of Medicine

e: [email protected]

www.twitter.com/UCDMedicine

Catherine Godson [Chair] Orina Belton

John CreanNeil Docherty

Carel leRouxFiona McGillicuddy

Donal O’SheaHelen Roche

Programme Committee


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