University of California, San Francisco Price List · 2016. 6. 23. · Unless otherwise stated, the...

RESEARCH MODELS AND SERVICES

2 0 1 6

University of California, San Francisco Price List

Customer Support CenterPhone: 1.877.CRIVER1 (1.877.274.8371) Email: [email protected]

Our expert technical group, including our highly qualified professional staff of veterinarians and doctorate-level scientists, can assist you in areas such as laboratory animal science, biology, husbandry, surgery and health issues.

Specifically, we can assist you with:

• Information regarding the Charles Riverportfolio

• Scheduling sample submissions

• Coordinating delivery of your complimentaryshipping materials

• Performing literature searches

• Running and interpreting results reports

• Answering questions about specific animal models

• Coordinating custom orders, including surgical procedures and genetically modified or preconditioned research models

Research Models Customer Service DepartmentPhone: 1.800.LAB.RATS (1.800.522.7287) Fax: 1.800.992.7329

Our customer service representatives strive to make the research model order and shipment process as easy as possible for you. When you call our Customer Service Department, our automated phone system directs your call (by area code) to your customer service team. This team concept lets you routinely speak with people who know you and your account. We offer five ways for you to order research models: phone, fax, mail, Electronic Data Interchange (EDI) and online ordering.

Specifically, we can assist you with:

• Animal orders

• Model availability

• Pricing and shipping details

Laboratory Testing Management® (LTM™) Help DeskPhone: 1.781.222.6701 Email: [email protected]

LTM™ is our online, interactive order entry and results management system that centralizes your health and genetic testing programs into one virtual location. Use LTM™ to search for tests and sample submission information, create and track orders, as well as archive and trend your testing results. Visit www.criver.com/ltm for details.

The LTM™ Help Desk can assist you with:

• Online ordering and sample shipping

• Results retrieval and interpretation

• Account management and troubleshooting

• One-on-one or group demonstrations and training

• Creating custom templates and reports

• Summarizing and trending data

If you are unsure about whom to contact at Charles River, we recommend that you start with our Customer Support Center. Our representatives are available from 6 a.m.–6 p.m. ET Monday through Friday to field any questions you may have, or to direct inquiries to the correct contact or department. For all correspondence: Charles River, 251 Ballardvale Street, Wilmington, MA 01887

www.criver.com CUSTOMER SUPPORT RESOURCES

CONTACT US

mailto:[email protected]


http://www.criver.com/ltm

www.criver.com

Filtered shipping container (Sew Easy™) 18.20 Filtered shipping container (Sew Easy™) 16.38 10% discountGnoto-safe™ shipping container 34.30 Gnoto-safe™ shipping container 30.87 10% discount

Air Freight 242.15 Air Freight 242.15Truck Freight 39.50 Truck Freight 39.50Truck Freight from Hollister & San Diego 39.50 Truck Freight 13.80 65% discountLocal Truck Freight 13.80 Local Truck Freight 10.35 25% discountRabbit Air Freight 242.15 Rabbit Air Freight 242.15

www.criver.com CHARLES RIVER RESEARCH MODELS AND SERVICES | US 2016

Unless otherwise stated, the following University of California, San Francisco pricing reflects a 0% discount off of the 2016 published Charles River research models and services price list.

2016 CHARLES RIVER LIST PRICE 2016 CUSTOMER PRICE

Crate Charges

Freight Charges

CRATE & FREIGHT

Weight in Grams Weight in GramsUp to 50 Up to 50

51-75 51-7576-100 76-100

101-125 101-125126-150 126-150151-175 151-175176-200 176-200201-225 201-225226-250 226-250251-275 251-275276-300 276-300301-325 301-325326-350 326-350351 plus 351 plus

Retired breeders Retired breedersLittermates 21 days old only Littermates 21 days old only

Lactating rat with litter Lactating rat with litterTimed pregnant Timed pregnant

Untimed pregnant Untimed pregnant*Estimated age

STRAIN CODE: 400 No discount


51-75 51-7576-100 76-100

101-125 101-125126-150 126-150151-175 151-175176-200 176-200201-225 201-225226-250 226-250251-275 251-275276-300 276-300301-325 301-325326-plus 326-plus

Retired Breeder Retired BreederLittermates (21 days old only) Littermates (21 days old only)

Lactating Rat with Litter Lactating Rat with LitterTimed Pregnant Timed Pregnant

Untimed Pregnant Untimed Pregnant*Estimated age

STRAIN CODE: 001

Sprague Dawley® Rats when ordering, specify SAS SD


14.80 14.8017.0019.9522.8524.6027.80


MALE FEMALE MALE FEMALE


CD® IGS Rats when ordering, specify CD

Prices upon request

FEMALE FEMALE MALEMALE

Prices upon requestPrices upon request44.05

23.2027.0529.6032.65

19.9522.8524.6027.8031.0034.6037.0538.8542.25

14.50

30.4517.65

102.35

31.0517.65

30.4517.65

102.3598.5578.85

31.0034.6037.0538.8542.2544.05

17.00

98.5578.85

Price Price Price Price

17.7521.1523.2027.0529.6032.6535.4538.05

14.5017.7521.15

35.4538.05

31.0517.65

Price Price15.50 15.5519.65 20.6024.20 25.2027.45 28.5531.70 35.0033.70 38.3039.30 41.2541.95 43.7045.60 47.4549.1051.2054.1559.45

39.4029.90

53.50

38.3029.90

140.70131.15110.00

25.71

Price13.3316.9020.8123.6127.2628.9833.8036.08

Price13.3717.7221.6724.5530.1032.9435.4837.5840.8146.01

32.9425.71

121.00112.7994.60

Prices upon request

39.2242.2344.0346.5751.13

33.88

OUTBRED RATS

Age in Days* Age in Days*Up to 21 Up to 21

22-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-7071-77 71-7778-84 78-84

85 Plus 85 PlusRetired breeders Retired breeders

Lactating rat with litter Lactating rat with litterUntimed pregnant Untimed pregnant

*Estimated age *Estimated age

STRAIN CODE: 006


51-75 51-7576-100 76-100

101-125 101-125126-150 126-150151-175 151-175176-200 176-200201-225 201-225226-250 226-250251-275 251-275276-300 276-300301-325 301-325326 plus 326 plus




STRAIN CODE: 118

Age in Days* Age in Days*28-42 28-42


50.7053.7557.4160.50

252.80

65.0669.4573.7080.6787.33

50.7053.7557.4160.5065.0669.45

55.04

58.9562.5066.7570.35

73.7080.6787.33

54.48

187.95

Long-Evans Rats

85.7093.80101.55

Prices upon request Prices upon request

218.55

Prices upon request

36.40

FEMALE

Price31.30

Sentinel Rats (Isolator-Maintained)

FEMALE

Price

64.00

FEMALE


Prices upon request

Price Price19.45

35.10

STRAIN CODE: 184CD® Hairless Rats

MALEPrice54.35

MALEPrice46.74

FEMALE Price54.35

FEMALE Price46.74


MALE FEMALE MALE


58.9562.5066.7570.3575.6580.75

75.65

217.41

80.7585.7093.80

101.55

63.35

19.7522.95 24.5527.75 29.1031.10 32.0533.9536.15 40.8040.00 43.1542.75 47.6048.55 51.5553.10 58.5055.8559.40

40.3031.15

39.9531.15

151.50140.60115.25

Price Price16.73 16.9919.74 21.1123.87 25.0326.75 27.5629.20 30.1931.09 35.0934.40 37.1136.77 40.9441.75 44.3345.67 50.3148.0351.08

34.6626.79

34.3626.79

130.29120.9299.12

OUTBRED RATS

STRAIN CODE: 003


51-75 51-7576-100 76-100

101-125 101-125126-150 126-150151-175 151-175176-200 176-200201-225 201-225226-250 226-250251-275 251-275276-300 276-300 301-325 301-325 326 plus 326 plus




STRAIN CODE: 273


51-75 51-7576-100 76-100

101-125 101-125126-150 126-150151-175 151-175176-200 176-200201-225 201-225226-250 226-250251-275 251-275276-300 276-300301-325 301-325326 plus 326 plus





FEMALE

Wistar Rats


MALE FEMALE

MALE FEMALE


MALE FEMALE


Wistar Han IGS Rats


MALE

44.5048.0550.2551.75

Price15.9021.2025.1529.2033.1036.8539.7042.3045.65

Price15.5519.7023.7527.6530.9032.8537.9041.05

38.2741.3243.2244.51

Price13.6718.2321.6325.1128.4731.6934.1436.3839.26

Price13.3716.9420.4323.7826.5728.2532.5935.30

33.4125.24

33.1125.24

118.59110.6492.54

38.8529.35

38.5029.35

137.90128.65107.60

Price Price16.45 16.5021.00 22.7025.50 27.0529.75 30.9532.45 35.8033.95 38.2038.50 41.8542.30 44.9046.7549.3551.9056.05

40.60 39.0530.80 30.80

144.70134.90112.90

Price Price14.15 14.1918.06 19.5221.93 23.2625.59 26.6227.91 30.7929.20 32.8533.11 35.9936.38 38.6140.21

116.0197.09

42.4444.6348.20

34.92 33.5826.49 26.49

124.44

OUTBRED RATS

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-7071-77 71-77

78 plus 78 plusRetired breeders Retired breeders

Littermates 21 days old only Littermates 21 days old onlyLactating rat with litter Lactating rat with litter

Timed pregnant Timed pregnantUntimed pregnant Untimed pregnant


Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70



Untimed pregnant Untimed pregnant*Estimated age *Estimated age

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-63






Prices upon request

41.6246.48

MALEPrice44.9848.5051.69

FEMALE Price42.7048.3354.52

238.65

Prices upon request

80.0599.50

131.05

40.08

60.5968.9378.4381.8787.81

68.8485.57

112.70

Age in Days*

Age in Days*Age in Days*MALE FEMALE

Age in Days*

MALE

Prices upon request

Brown Norway Rats when ordering, specify BNSTRAIN CODE: 091

Copenhagen RatsSTRAIN CODE: 286

Fischer Rats when ordering, specify CDF ™

STRAIN CODE: 002

FEMALE MALEAge in Days* Age in Days*

MALE FEMALE

Prices upon request

Prices upon request

Price52.3056.4060.10

49.40

69.0584.1587.5599.50



70.4580.1591.2095.20102.10

48.4054.05 46.48

280.02205.24

MALE FEMALE

105.35

47.8549.00

Price43.9543.9555.3566.8080.8580.8594.4594.45

121.90

46.0549.00

275.00229.15210.25

Price43.3043.30

60.20

104.83

39.6042.14

236.50197.07180.82

Price37.2437.2442.4851.7759.3872.3775.2985.57

Prices upon request

Price37.8037.8047.6057.4569.5369.5381.2381.23

29.8533.0036.2544.3549.5559.3059.30

90.60

41.1542.14

49.6556.2063.40

46.6054.05

325.60

FEMALE Price

Price

43.3045.80

42.4545.80

242.85197.40177.60

Price25.2026.0632.2538.5342.1447.4350.44

Price29.3030.3037.5044.8049.0055.1558.65

Price

208.85169.76152.74

37.2439.39

25.6728.3831.1838.1442.6151.0051.00

36.5139.39

INBRED RATS

STRAIN CODE: 403 No discount

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-63





Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70





45.97 44.7253.71 48.2057.58 53.1560.54 53.15

Price Price28.12 27.1831.99 30.9235.82 35.0037.84 38.79

35.6936.64 36.64

173.98149.68116.57

42.60 42.60202.30174.05135.55

37.07

53.45 52.0062.45 56.0566.95 61.8070.40 61.80

43.10 41.50Prices upon request

Price Price32.70 31.6037.20 35.9541.65 40.7044.00 45.10

62.1038.0062.10

240.85114.9593.15

38.0062.10

240.85114.9593.15

Price Price27.20 27.9529.10 30.9533.15 30.9536.90 34.9542.05 40.0052.70 44.7054.35

39.10

42.05 40.0052.70 44.7054.35 44.70

39.1062.10

Price Price27.20 27.9529.10 30.9533.15 30.9536.90 34.95


Prices upon request

MALE FEMALE

MALE FEMALE MALE

Age in Days*

Lewis RatsSTRAIN CODE: 004

FEMALE


Age in Days*

MALE FEMALE

Age in Days*


Age in Days*

F344 Rats when ordering, specify SAS FISCH


INBRED RATS

Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-56

57 plus 57 plusTimed Pregnant Timed Pregnant


Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-56

57 plus 57 plusTimed Pregnant Timed Pregnant


Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70

71 plus 71 plus*Estimated age *Estimated age

Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70


Prices upon Request Prices upon Request

Obese Resistant Rats when ordering, specify OR-CDSTRAIN CODE: 462

Age in Days*MALE FEMALE



249.00 249.45283.55 285.25 283.55 285.25



188.35 192.55 188.35 192.55216.85 219.15 216.85

105.10 104.75 105.10132.85 130.15 132.85 130.15159.75 161.20 159.75 161.20

104.75

Price104.75132.85159.75188.35216.85249.00283.55

FEMALE Price

104.40111.90117.65124.95130.50

MALEPrice

110.40118.35124.45132.15138.00

251.75

FEMALE Price

102.45109.70115.45122.55127.95

MALEPrice

Prices upon Request

104.45111.85117.70124.90130.45

251.75

FEMALE Price

102.45109.70115.45122.55127.95

Price

Prices upon Request

2016 CUSTOMER PRICE2016 CHARLES RIVER LIST PRICE

Dahl/Salt Sensitive Rats (Dahl/SS)

256.75

FEMALE Price

104.40111.90117.65124.95130.50

Prices upon Request

249.00 249.45

FEMALE

256.75

FEMALE Price

105.10130.15161.20

192.55219.15249.45285.25

219.15

192.55219.15249.45285.25

MALE

STRAIN CODE: 320

Age in Days*Age in Days*MALE

Price104.75132.85159.75188.35

PriceMALE

MALEPrice

110.40118.35124.45132.15138.00

Prices upon Request

104.45111.85117.70124.90130.45


SS-13BN Rats (control for the Dahl/SS)STRAIN CODE: 334

Age in Days*

Age in Days* Age in Days*

Age in Days*

Obese Prone Rats when ordering, specify OP-CDSTRAIN CODE: 463

216.85249.00283.55

105.10130.15161.20

DISEASE AND TRANSLATIONAL RATS

Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-56


Obese Lean +/? Obese Lean +/? Obese Lean +/? Obese Lean +/?Up to 42 425.45 184.45 301.05 148.70 Up to 42 425.45 184.45 301.05 148.70

43-49 436.65 198.05 314.05 161.60 43-49 436.65 198.05 314.05 161.6050-56 452.65 211.70 326.85 174.40 50-56 452.65 211.70 326.85 174.4057-63 466.30 225.40 339.85 187.25 57-63 466.30 225.40 339.85 187.2564-70 479.95 238.95 352.80 200.15 64-70 479.95 238.95 352.80 200.15


Up to 21 Up to 21 22-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-7071-77 71-7778-84 78-8485-91 85-9192-98 92-98

99-105 99-105106 Plus 106 Plus




288.75 288.75

94.10 94.10 94.10 94.10394.40 394.40308.05 308.05

165.25 155.45 165.25 155.45Prices upon request Prices upon request

89.25 85.95 89.25 85.95

127.95 120.25 127.95 120.25141.25 132.80 141.25 132.80150.15 141.20 150.15 141.20

97.40 96.80 97.40 96.80106.10 105.45 106.10 105.45116.65 109.75 116.65 109.75

75.85 75.75 75.85 75.7580.95 80.90 80.95 80.9088.85 88.75 88.85 88.75

60.80 58.50 60.80 58.5063.35 61.40 63.35 61.4068.40 65.85 68.40 65.85

Age in Days*

MALE FEMALE Age in Days*

MALE FEMALE Price Price Price Price

FEMALE Price

133.70143.45150.70160.10167.00

MALEPrice

136.30146.20

Age in Days*

SHR Rats




Prices upon request

PCK RatsSTRAIN CODE: 453

Age in Days*

STRAIN CODE: 007

143.45150.70160.10167.00

MALE PRICE

153.60163.15170.20

MALEPrice

136.30146.20153.60163.15170.20

FEMALE Price

133.70

FEMALE PRICE

Prices upon request

MALE PRICEAge in Days*

FEMALE PRICE


Age in Days*

SHHF RatsSTRAIN CODE: 373 (Obese), 374 (Lean +/?)


Up to 21 Up to 21 22-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-7071-77 71-7778-84 78-8485-91 85-9192-98 92-98

99-105 99-105106 Plus 106 Plus




Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-56

57 plus 57 plus


Obese Lean fa/+ Lean +/? Obese Lean fa/+ Lean +/? Up to 42 368.50 188.75 149.85 Up to 42 368.50 188.75 149.85

43-49 380.75 201.85 162.95 43-49 380.75 201.85 162.9550-56 393.25 214.85 175.95 50-56 393.25 214.85 175.9557-63 405.75 227.75 188.75 57-63 405.75 227.75 188.7564-70 418.05 240.95 201.85 64-70 418.05 240.95 201.85

71 plus 71 plus

Obese Lean fa/+ Lean +/? Obese Lean fa/+ Lean +/? Up to 42 262.95 188.75 149.85 Up to 42 262.95 188.75 149.85

43-49 275.35 201.85 162.95 43-49 275.35 201.85 162.9550-56 287.90 214.85 175.95 50-56 287.90 214.85 175.9557-63 300.30 227.75 188.75 57-63 300.30 227.75 188.7564-70 312.65 240.95 201.85 64-70 312.65 240.95 201.85


Stroke Prone Rats when ordering, specify SHRSPSTRAIN CODE: 324




128.50139.90152.75

87.6092.35

113.05123.80


288.75

88.30

68.1082.1588.3097.95

104.60

128.50139.90152.75

308.05288.75

Age in Days*

MALE PRICE

Age in Days*

MALE PRICE


Prices upon request

136.80 129.35 136.80 129.35145.90 137.95 145.90 137.95160.30 151.55 160.30 151.55


123.45 116.70 123.45 116.70

147.20Prices upon request

134.75

ZDF RatsSTRAIN CODE: 370 (Obese), 380 (Lean fa/+), 371 (Lean +/?)

69.9580.6086.65

134.75147.20

114.15 107.90 114.15 107.90

96.10

68.1082.15

117.35

97.95104.60117.35 113.05

123.80

100.80

69.9580.6086.6596.10

100.80

53.8558.70

WKY Rats (control for the SHR)STRAIN CODE: 008

Age in Days*MALEPrice48.7053.8558.70

FEMALE

47.7552.8557.60

MALEPrice Price

87.60

62.15 62.1560.95

48.70

FEMALE Price47.7552.8557.6060.95

Age in Days*



85.9592.35

394.40308.05

92.35394.40

92.35

Age in Days*FEMALE PRICE

Age in Days*FEMALE PRICE


85.95


Obese Lean +/? Obese Lean +/? Obese Lean +/? Obese Lean +/?Up to 42 369.50 144.95 267.30 142.85 Up to 42 369.50 144.95 267.30 142.85

43-49 383.05 158.30 280.55 156.05 43-49 383.05 158.30 280.55 156.0550-56 396.25 171.70 293.90 169.30 50-56 396.25 171.70 293.90 169.3057-63 409.45 184.85 307.30 182.90 57-63 409.45 184.85 307.30 182.9064-70 422.90 198.25 320.75 196.00 64-70 422.90 198.25 320.75 196.00


STRAIN CODE: 185 (Obese), 186 (lean) 6% discount

Obese Lean Obese Lean Obese Lean Obese LeanUp to 28 250.85 63.90 241.55 61.55 Up to 28 235.80 60.07 227.06 57.86

29-35 262.25 66.45 252.55 64.00 29-35 246.52 62.46 237.40 60.1636-42 274.65 69.15 264.50 66.60 36-42 258.17 65.00 248.63 62.6043-49 288.80 78.25 278.10 75.35 43-49 271.47 73.56 261.41 70.8350-56 310.10 86.15 298.60 82.95 50-56 291.49 80.98 280.68 77.9757-63 327.45 94.15 315.30 90.65 57-63 307.80 88.50 296.38 85.2164-70 344.10 98.20 331.35 94.55 64-70 323.45 92.31 311.47 88.8871-77 360.00 102.15 346.65 98.35 71-77 338.40 96.02 325.85 92.4578-84 369.60 106.45 355.90 102.50 78-84 347.42 100.06 334.55 96.3585-91 380.60 112.70 366.50 108.55 85-91 357.76 105.94 344.51 102.04

Retired breeders 109.50 Retired breeders 102.93*Estimated age *Estimated age

MALE PRICE FEMALE PRICE



Age in Days*

STRAIN CODE: 378 (Obese), 379 (Lean +/?)MALE PRICE

Age in Days*MALE PRICE



ZSF1 Rats


FEMALE PRICE FEMALE PRICE

Zucker Rats

FEMALE PRICEMALE PRICE


Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56


Up to 12 Up to 1213-15 13-1516-18 16-1819-21 19-2122-24 22-24


Littermates 21 days old only Littermates 21 days old onlyLactating mouse with litter Lactating mouse with litter


Up to 21 Up to 2122 - 28 22 - 2829 - 35 29 - 3536 - 42 36 - 4243 - 49 43 - 4950 Plus 50 Plus

**Isolator-maintained **Isolator-maintained

Up to 12 Up to 1213-15 13-1516-18 16-1819-21 19-2122-24 22-24




46.7030.79

6.45 6.45

6.45 6.157.57 7.57

68.71

Prices upon request

Price Price5.68 5.556.19 6.196.24 6.246.32 6.32

7.25 7.257.35 7.357.50 7.50

7.50 7.158.80 8.80

6.157.74

70.0547.6031.39

7.359.00

7.159.00

81.4555.3536.50

6.36 6.366.41 6.416.45 6.45

6.327.74

Prices upon request

11.9513.2013.75

FEMALE

PRICE11.5011.8012.4512.8513.4514.20

MALE

PRICE10.6510.8011.55

11.0511.5712.21

MALE

PRICE9.16

MALE

Prices upon request

21.55

MALEPRICE19.3021.30

FEMALE

MALE MALE

MALEPRICE16.60

7.457.50

Price Price


Prices upon request

18.3218.5318.7118.83

FEMALE PRICE

18.3218.53

Prices upon request

21.30

6.70 6.707.35 7.357.40 7.407.45

7.50

Price Price5.76 5.766.32 6.32

FEMALE



FEMALE PRICE18.6520.9521.15

Prices upon request

79.9054.3035.80

FEMALE MALEPrice Price6.60 6.457.20 7.20

Prices upon request


Black Swiss MiceSTRAIN CODE: 492

Weight in Grams Weight in Grams


16.0418.0218.19

9.299.93

10.2811.3511.83

FEMALE

PRICE9.89

10.1510.71

FEMALE


CD-1® IGS MiceSTRAIN CODE: 022

CF-1™ MiceSTRAIN CODE: 023

CD1-Elite Mice**STRAIN CODE: 482

21.5521.7521.90

Prices upon request

OUTBRED MICE

Up to 12 Up to 1213-15 13-1516-18 16-1819-21 19-2122-24 22-24




Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56



Untimed pregnant Untimed pregnant*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained

STRAIN CODE: 491

Age in Weeks* Age in Weeks*4-6 4-6


36.15

Price Price5.63 5.636.15 6.246.19 6.286.41 6.416.54 6.54

6.24 6.157.65 7.65

69.3647.1731.09

80.6554.85

8.90

262.30

MALEPRICE

314.33

32.8535.3938.4040.3341.2443.17

225.58

Prices upon requestPrices upon request

40.3341.2443.17

42.0148.85137.40

365.50

35.39

Prices upon request

FEMALE

MALEPRICE

MALEFEMALE MALE

FEMALE FEMALE

38.40

47.9550.20

48.85

Price Price6.55 6.557.15 7.257.20 7.307.45 7.457.60 7.60

7.25 7.158.90

42.01

2016 CUSTOMER PRICE

46.90



CFW® Mice (Swiss Webster)STRAIN CODE: 024

SKH1-Elite Mice**STRAIN CODE: 477

2016 CHARLES RIVER LIST PRICE

Prices upon request


PRICE

118.16118.16

PRICE

137.40


32.85

12.50 10.75

Sentinel Mice (Isolator-Maintained)

FEMALE FEMALE

Price Price

41.1544.6546.9047.9550.20

38.20 38.2041.1544.65

OUTBRED MICE

Up to 28 Up to 2829 - 35 29 - 3536 - 42 36 - 4243 - 49 43 - 4950 - 56 50 - 5657 plus 57 plus

Retired breeders Retired breedersLittermates 21 days old only Littermates 21 days old onlyLactating mouse with litter Lactating mouse with litter

Untimed pregnant Untimed pregnant*Estimated age *Estimated age**Isolator maintained **Isolator maintained

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56


Lactating mouse with litter Lactating mouse with litterUntimed pregnant Untimed pregnant



*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56




27.4834.30 34.30 29.50 29.50

27.80 27.80 23.91 23.91

36.70 36.70 31.56 31.5639.10 39.10 33.63 33.6341.45 41.45 35.65 35.65

B6-Ly5.1/Cr MiceSTRAIN CODE: 564

Age in Days*

MALE FEMALE

Age in Days*

MALE FEMALE PRICE PRICE PRICE PRICE29.55 29.55 25.41



25.4131.95 31.95 27.48

FEMALE PRICE27.8231.39

29.8431.18

21.8431.65

Prices upon request22.0631.65

185.07166.41193.50

25.4036.80215.20

55.60 55.6057.05 57.0565.25

129-Elite Mice**STRAIN CODE: 476

FEMALE PRICE32.3536.5038.5541.0545.70

25.9329.2031.39

38.55

PRICE

Prices upon request

Age in Days*

MALE

25.65

33.9536.50

47.10 47.1048.40 48.4050.85 50.85

40.51PRICE

36.80

A/JCr MiceSTRAIN CODE: 563

Age in Days*

MALE FEMALEPRICE PRICE

33.1535.3039.30



MALEPRICE30.15

Age in Days*

43.1033.1537.07

65.25

47.8249.06 49.06

Age in Days*

MALE

47.82

Prices upon request67.08 66.44

FEMALEPRICE

221.36177.03

40.5141.62 41.6243.73 43.73

56.12 56.12

257.40205.85

Prices upon request78.00 77.25

STRAIN CODE: 493MALEFEMALE

Age in Days*

MALE

B6 Albino Mice**

PRICE34.1035.6037.0543.4546.70

Age in Days*

FEMALE PRICE29.3330.6231.8637.37

37.70 32.4240.8543.95 40.16

PRICE34.7036.25

35.1337.80

PRICE

INBRED MICE

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70


Littermates 21 days old only Littermates 21 days old onlyLactating mouse with litter Lactating mouse with litterTimed/Untimed pregnant Timed/Untimed pregnant


Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-63


*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70



*Estimated age *Estimated age181.00 155.66

22.60 22.60 19.44 19.4435.15 35.15 30.23 30.23

211.40 181.80

38.15 37.00 32.81 31.8244.95 37.70 38.66 32.42


27.0035.45 33.75 30.49 29.0336.10 34.35 31.05 29.54

C3H MiceSTRAIN CODE: 025

Age in Days*

MALE FEMALE

Age in Days*

MALE FEMALE PRICE PRICE PRICE PRICE23.45 24.95 20.17 21.4627.60 28.50

Prices upon request Prices upon request31.30 31.30 26.92 26.92

23.74 24.5128.75 29.50 24.73 25.3731.40 31.40 27.00

43.40 43.60 37.32 37.5045.45 44.90 39.09 38.6147.45 45.90 40.81 39.47

36.70 39.60 31.56 34.0638.05 40.95 32.72 35.2239.10 42.20 33.63 36.29

MALE FEMALE PRICE PRICE PRICE PRICE31.70 34.15 27.26 29.37



28.08

21.24 22.5326.35 27.05 22.66 23.2629.45 28.70 25.33 24.6830.00 29.25


18.36 19.3924.70 26.20

FEMALE FEMALE MALE MALEAge in Days* Age in Days*PRICE PRICE PRICE PRICE

BALB/c MiceSTRAIN CODE: 028

21.35 22.55

25.80 25.1633.30 31.20 28.64 26.8333.95 31.80 29.20 27.3534.60 32.45 29.76 27.91


192.50 165.55163.45 140.57

28.0832.65 32.65

BALB/c-Elite Mice** STRAIN CODE: 547

Age in Days*

MALE FEMALE

Age in Days*

INBRED MICE

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70




Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-63




Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-5657-63 57-6364-70 64-70





193.40 166.32

27.35 27.35 23.52 23.5237.75 37.75 32.47 32.47

221.70 190.66

40.50 40.10 34.83 34.4944.45 40.85 38.23 35.1345.30 42.75 38.96 36.77

33.05 30.06 28.4236.85 38.70 31.69 33.2839.75 39.45 34.19 33.93

DBA/2 Mice

47.30 47.30 40.68 40.68366.45 315.15243.90 209.75


31.90 31.90 27.43 27.43

41.85 44.15

STRAIN CODE: 026



PRICE PRICE PRICE PRICE30.85 32.45 26.53 27.9134.95

35.99 37.9748.95 45.00 42.10 38.7049.90 46.00 42.91 39.56

31.60 34.80 27.18 29.9336.65 40.20 31.52 34.5739.50 43.35 33.97 37.28

MALE FEMALE Age in Days*

MALE FEMALE PRICE PRICE PRICE PRICE

27.22244.70 210.44

C57BL/6-Elite Mice**STRAIN CODE: 475

Age in Days*

203.50 175.01

33.40 30.90 28.72 26.5733.75 31.50 29.03 27.0934.55 32.10 29.71 27.61



21.70 21.10 18.66 18.1531.65 31.65 27.22

18.06 19.4824.30 26.1026.3528.50 28.95 24.51

20.90 22.4527.40 22.66 23.56

24.90

21.00 22.65

32.80

MALE FEMALE MALESTRAIN CODE: 027

FEMALE Age in Days* Age in Days*PRICE PRICE PRICE PRICE

29.50 28.21 25.37

C57BL/6 Mice



INBRED MICE

Up to 28 Up to 2829-35 29-3536-42 36-4243-49 43-4950-56 50-56

57 plus 57 plus*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained

Up to 21 Up to 2122-35 22-3536-49 36-4950-63 50-6364-77 64-7778-91 78-91


Timed /Untimed pregnant Timed /Untimed pregnant*Estimated age *Estimated age


Retired breeders Retired breedersLittermates 21 days old only Littermates 21 days old onlyLactating mouse with litter Lactating mouse with litter


205.60 176.82

25.55 25.55 21.97 21.9733.90 33.90 29.15 29.15

238.65 205.24

35.30 38.55 30.36 33.1537.05 40.55 31.86 34.87


29.55 31.80 25.41 27.3531.55 33.45 27.13 28.7733.30 38.00 28.64 32.68

SJL-Elite Mice**STRAIN CODE: 478



PRICE PRICE PRICE PRICE


236.75 203.61

35.75 37.65 30.75 32.3842.45 44.20 36.51 38.0148.85 49.85 42.01 42.87

23.30 25.85 20.04 22.2325.95 28.40 22.32 24.4230.05 32.60 25.84 28.04

88.20 88.20 75.85Prices upon request Prices upon request

FVB MiceSTRAIN CODE: 207



PRICE PRICE PRICE PRICE

75.85

70.60 70.60 60.7277.95 77.95 67.0483.20 83.20 71.55


Age in Days*PRICE

Fox Chase CB17™ Mice** STRAIN CODE: 251

2016 CUSTOMER PRICE



60.7267.0471.55

MALEPRICE56.63


65.85PRICE65.85

FEMALE PRICE56.63

INBRED MICE

Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56

57 plus 57 plusLittermates 21 days old only Littermates 21 days old only


Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56



Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56



Up to 21 Up to 2122-28 22-2829-35 29-3536-42 36-4243-49 43-4950-56 50-56



29.37 27.6129.37 27.61

31.69 31.69

23.13 24.0825.67 24.9425.67 25.93

Prices upon request

34.15 32.1034.15 32.10

36.85 36.85

26.90 28.0029.85 29.0029.85 30.15

Prices upon request

29.84 29.84

Price Price22.50 24.60

Price Price19.35 21.16

34.70 34.70

32.5529.90 32.55

Price Price19.69 21.4622.70 25.3323.39 25.9724.30 27.99

26.53

29.80 29.80

Price Price

42.15 30.85

34.65 34.65

36.25

23.6127.86 24.7330.83 26.53

Price17.97 20.0820.73 22.58

Price

23.2227.00 27.4532.40 28.7535.85 30.85

Price Price20.90 23.3524.10 26.25

31.95

Price22.2025.6527.6033.10

27.48

30.01 30.01

24.9028.47 27.4831.30 27.48

Price19.09 20.6422.06 24.17


B6C3F1 Mice

B6D2F1 Mice when ordering, specify BDF1

CB6F1 Mice


Age in Days*FEMALE MALE

Prices upon requestPrices upon request43.30 31.95

34.90 34.90

Price

23.74

37.2436.40



Age in Days*


Age in Days*

CD2F1 Mice when ordering, specify CDF1

22.90 24.9526.40 29.4527.20 30.20

25.71 27.9925.71 27.99

28.25 32.5529.90


STRAIN CODE: 033

STRAIN CODE: 176

STRAIN CODE: 099

MALE FEMALE MALE FEMALE


FEMALE

Age in Days*MALE


STRAIN CODE: 031

FEMALE

Age in Days*MALE

Price24.0028.1028.9531.95

HYBRID MICE

MALE FEMALE MALE FEMALE Price Price Price Price

Up to 28 99.50 99.50 Up to 28 99.50 99.5035 108.00 108.00 35 108.00 108.0042 116.75 116.75 42 116.75 116.7549 125.45 125.45 49 125.45 125.4556 134.20 134.20 56 134.20 134.20

57 plus 57 plus*Estimated age *Estimated age**Isolator-maintained **Isolator-maintained






PGP Mice** P-glycoprotein DeficientSTRAIN CODE: 291

DISEASE AND TRANSLATIONAL MICE

STRAIN CODE: 490 (Homozygous), 491 (Heterozygous)§ 14% discount on 1st tier only

1-100 101-250 251+ 1-100 101-250 251+Up to 42 72.45 54.45 45.50 Up to 42 62.31 54.45 45.50

43-56 80.25 62.60 53.40 43-56 69.02 62.60 53.4057-63 91.30 73.50 65.25 57-63 78.52 73.50 65.25

64 Plus 64 Plus

1-100 101-250 251+ 1-100 101-250 251+Up to 42 84.20 63.30 53.00 Up to 42 72.41 63.30 53.00

43-56 93.40 73.75 63.40 43-56 80.32 73.75 63.4057-63 105.75 85.05 75.15 57-63 90.95 85.05 75.15

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient §Heterozygous (haired) animals are not immunodeficient.

MALE FEMALE MALE FEMALE PRICE PRICE PRICE PRICE

Up to 28 80.20 80.20 Up to 28 68.97 68.9729-35 85.70 85.70 29-35 73.70 73.7036-42 91.70 91.70 36-42 78.86 78.8643-49 96.60 96.60 43-49 83.08 83.0850-56 102.10 102.10 50-56 87.81 87.81

57 plus 57 plus*Estimated age *Estimated age**Congenic, isolator-maintained **Congenic, isolator-maintained


Up to 28 84.20 85.00 Up to 28 72.41 73.1029-35 89.10 90.00 29-35 76.63 77.4036-42 94.90 94.90 36-42 81.61 81.6143-49 100.20 100.20 43-49 86.17 86.1750-56 105.20 105.20 50-56 90.47 90.47



Up to 42 118.55 125.70 Up to 42 101.95 108.1043-56 128.20 138.70 43-56 110.25 119.28

56 Plus 56 Plus*Estimated age *Estimated age**Congenic, isolator-maintained **Congenic, isolator-maintained

HOMOZYGOUS PRICINGMALES (QUANTITY)

Prices upon request




Prices upon request

Prices upon request

Age in Days*

Age in Days*

Age in Days*

Age in Days*FEMALES (QUANTITY)

Prices upon request

FEMALES (QUANTITY)HOMOZYGOUS PRICING

Prices upon request

Prices Upon Request




Age in Days*

Age in Days*

Fox Chase SCID® Mice** When Ordering, Specify C.B-17 SCIDSTRAIN CODE: 236

Fox Chase SCID® Beige Mice**STRAIN CODE: 250

Athymic Nude Mice**


Prices Upon Request

Prices Upon Request

NOD SCID Mice**STRAIN CODE: 394

HOMOZYGOUS PRICING

IMMUNODEFICIENT MODELS

PRICE PRICE166.95 143.5861.40 52.80

Prices Upon Request Prices upon request

**Inbred, isolator-maintained *Inbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.

STRAIN CODE: 086 (Homozygous), 087 (Heterozygous)§ 251+ pricing

1-100 101-250 251+ 1-100 101-250 251+Up to 42 72.45 54.45 45.50 Up to 42 45.50 45.50 45.50

43-56 80.25 62.60 53.40 43-56 53.40 53.40 53.4057-63 90.40 72.75 64.60 57-63 64.60 64.60 64.60

64 Plus 64 Plus

1-100 101-250 251+ 1-100 101-250 251+Up to 42 84.20 63.30 52.95 Up to 42 52.95 52.95 52.95

43-56 93.40 73.75 63.40 43-56 63.40 63.40 63.4057-63 105.75 85.05 75.15 57-63 75.15 75.15 75.15

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.

PRICE PRICE96.15 82.6949.50 42.57

*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.

STRAIN CODE: 088 (Homozygous), 089 (Heterozygous)§ 251+ pricing

1-100 101-250 251+ 1-100 101-250 251+Up to 42 72.45 54.45 45.50 Up to 42 45.50 45.50 45.50

43-56 80.25 62.60 53.40 43-56 53.40 53.40 53.4057-63 90.40 72.75 64.60 57-63 64.60 64.60 64.60

64 Plus 64 Plus

1-100 101-250 251+ 1-100 101-250 251+Up to 42 84.20 63.30 53.00 Up to 42 53.00 53.00 53.00

43-56 93.40 73.75 63.40 43-56 63.40 63.40 63.4057-63 104.70 84.25 74.45 57-63 74.45 74.45 74.45

64 Plus 64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.


MALES (QUANTITY)

HOMOZYGOUS PRICING**FEMALES (QUANTITY)

HOMOZYGOUS PRICING

Prices upon request


Prices upon request

Age in Days*

Age in Days*

Age in Days*



STRAIN CODE: 201 (Homozygous), 202 (Heterozygous)§

Age in Days*

Age in Days*

MALES (QUANTITY)

Prices Upon Request

Prices upon request

NIH III Nude Mice**

Age in Days*

Age in Days*

HOMOZYGOUS PRICING**

NU/NU BALB/c Mice**STRAIN CODE: 194 (Homozygous), 195 (Heterozygous)§

NU/NU- CD-1® Mice**


Prices upon request

NU/NU Mice**

FEMALES (QUANTITY)

Homozygous, either sex nu/nu, 28-42 days*

Prices upon request

Heterozygous, either sex nu+, 28-42 days*Homozygous, either sex nu/nu, 28-42 days*Heterozygous, either sex nu+, 28-42 days*

Homozygous, either sex nu/nu, 28-42 days*Heterozygous, either sex nu+, 28-42 days*43 plus*Estimated age

Homozygous, either sex nu/nu, 28-42 days*

Prices upon request Prices Upon Request

Heterozygous, either sex nu+, 28-42 days*43 plus*Estimated age

HOMOZYGOUS PRICINGFEMALES (QUANTITY)

Age in Days*

HOMOZYGOUS PRICINGFEMALES (QUANTITY)

HOMOZYGOUS PRICING


HOMOZYGOUS HOMOZYGOUS HOMOZYGOUS HOMOZYGOUSMALE FEMALE MALE FEMALE PRICE PRICE PRICE PRICE

Up to 4 145.70 148.45 Up to 4 125.30 127.675 182.40 182.40 5 156.86 156.866 219.15 219.15 6 188.47 188.477 252.95 252.95 7 217.54 217.548 290.00 290.00 8 249.40 249.409 323.35 323.35 9 278.08 278.08

10 357.85 361.15 10 307.75 310.5911 plus 11 plus

*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained§Heterozygous (haired) animals are not immunodeficient. §Heterozygous (haired) animals are not immunodeficient.


Up to 28 100.15 100.15 Up to 28 86.13 86.1329-35 106.90 106.90 29-35 91.93 91.9336-42 113.30 113.30 36-42 97.44 97.4443-49 119.35 119.35 43-49 102.64 102.6450-56 126.15 126.15 50-56 108.49 108.49


STRAIN CODE: 474 14% discount on 1st tier only

1-100 101-250 251+ 1-100 101-250 251+Up to 42 87.10 65.50 54.75 Up to 42 87.10 65.50 54.75

43-56 96.60 75.20 64.25 43-56 96.60 75.20 64.2557-63 109.80 88.50 78.40 57-63 109.80 88.50 78.40

64 Plus 64 Plus

1-100 101-250 251+ 1-100 101-250 251+Up to 42 101.35 76.20 63.70 Up to 42 101.35 76.20 63.70

43-56 112.35 88.80 76.25 43-56 112.35 88.80 76.2557-63 124.90 100.50 88.85 57-63 124.90 100.50 88.85

64 Plus*Estimated age *Estimated age**Outbred, isolator-maintained **Outbred, isolator-maintained


Up to 21 92.55 92.55 Up to 21 79.59 79.5922-28 94.65 94.65 22-28 81.40 81.4029-35 96.75 96.75 29-35 83.21 83.2136-42 98.80 98.80 36-42 84.97 84.9743-49 100.90 100.90 43-49 86.77 86.7750-56 103.00 103.00 50-56 88.58 88.58

57 plus 57 plus

**Inbred, isolator-maintained **Inbred, isolator-maintained


Prices Upon Request Prices Upon Request


SCID/NCr Mice** (BALB/c background)STRAIN CODE: 561


STRAIN CODE: 488

Age in Weeks* Age in Weeks*

Prices upon request

Prices upon requestPrices Upon Request

Prices upon request

MALE QUANTITY AND PRICING MALE QUANTITY AND PRICING

SCID Hairless Outbred Mice* when ordering, specify SHO ®


Prices upon requestPrices Upon Request

Age in Days*

Age in Days*

Age in Days*

Age in Days*



NUDE RATS** When Ordering, Specify RNUSTRAIN CODE: 316 (Homozygous), 118 (Heterozygous)§

SCID Hairless Congenic Mice** when ordering, specify SHC™


FEMALE QUANTITY AND PRICINGFEMALE QUANTITY AND PRICING


Up to 200 Up to 200201-250 201-250251-300 251-300301-350 301-350351-400 351-400401-450 401-450451-500 451-500501-550 501-550551 plus 551 plus

Retired breeders Retired breeders

Up to 200 Up to 200201-250 201-250251-300 251-300301-350 301-350351-400 351-400401-450 401-450451-500 451-500501-550 501-550551 plus 651 plus

Up to 50 Up to 5051-60 51-6061-70 61-7071-80 71-8081-90 81-9091-100 91-100

101-110 101-110111-120 111-120121 plus 131 plus

Retired breeders Retired breedersTimed pregnant Timed pregnant105.70

Price Price25.41 25.4128.12 28.1230.62 30.6234.53 34.53

90.90

45.20 45.2050.60 50.6054.55 54.5556.80 56.80

46.05 46.05

38.87 38.8743.52 43.5246.91 46.9148.85 48.85

39.60 39.60

Price Price29.55 29.5532.70 32.7035.60 35.6040.15 40.15



124.79130.46140.74

MALEPrice

191.50206.35230.60251.20271.65287.20297.40

FEMALEPrice

198.32

164.69177.46198.32

164.69177.46

30.0630.06Prices upon request Prices upon request

118.51

34.9534.95

103.11

Either SexPrice64.9370.7876.4581.2786.0489.8794.43109.80

119.90

233.62246.99255.76277.01

216.03233.62246.99255.76277.01

216.03230.60

2016 CUSTOMER PRICE2016 CHARLES RIVER LIST PRICE

Hartley Guinea PigsSTRAIN CODE: 051

IAF Hairless Guinea PigsSTRAIN CODE: 161

STRAIN CODE: 049

Weight in Grams

Prices upon request

271.65

94.50

Either SexPrice75.5082.3088.90

Weight in Grams

LVG Golden Syrian Hamsters


Prices upon request

Weight in Grams

Weight in Grams

MALE FEMALE

287.20297.40322.10322.10

MALE

251.20

89.87100.36106.30112.49

PriceWeight in Grams

FEMALEPrice

MALE FEMALE Weight in Grams

Specified SexPricePrice

104.50116.70123.60130.80137.80145.10151.70163.65

Specified Sex

100.05104.50

191.50206.35

GUINEA PIGS & HAMSTERS

Up to 40 Up to 4041-50 41-5051-60 51-6061-70 61-7071-80 71-8081-90 81-90

91 Plus 91 PlusRetired Breeder Retired Breeder

Proven Breeder Pair Proven Breeder PairUntimed Pregnant Untimed Pregnant

Lactating mother with pups Lactating mother with pups

Weight Weight Kgs Lbs Kgs Lbs1.4-1.8 3-4 1.4-1.8 3-41.9-2.3 4-5 1.9-2.3 4-52.4-2.7 5-6 2.4-2.7 5-62.8-3.0 6-7 2.8-3.0 6-7

3.1-3.3 7 3.1-3.3 7 3.4 - 3.6 8 3.4 - 3.6 8 3.7-3.9 8-9 3.7-3.9 8-9

187.57207.95218.10

Price Price59.81 56.9361.62 59.8166.31 61.6268.28 64.0770.65 68.2874.56

59.81 59.81170.32178.84

79.40 74.5082.15 79.4086.70

69.55 69.55198.05


Price Price69.55 66.2071.65 69.5577.10 71.65


286.20

Specified SexPrice

151.15179.25208.15233.65269.30292.45303.35

Either SexPrice

126.60153.95182.70

179.01208.38228.20246.13

Specified SexPrice

129.99154.16179.01200.94231.60251.51260.88

Either SexPrice

108.88132.40157.12

208.15

STRAIN CODE: 052New Zealand White Rabbits

242.30265.35


Weight in Grams Weight in GramsMALE FEMALE

STRAIN CODE: 243Mongolian Gerbils


MALE FEMALE

GERBILS & RABBITS

LIST CUSTOMER LIST CUSTOMER LIST CUSTOMER CODE RAT PRICE*† RAT PRICE*† MOUSE PRICE*† MOUSE PRICE*† G.PIG PRICE*† G.PIG PRICE*†

Carotid Artery, Common CARART 96.80 96.80 151.60 151.60 130.70 130.70Carotid Artery - Cranial Dosing CARART-CD 96.80 96.80 155.90 155.90 - -Femoral Artery FEMART 112.00 112.00 - - - -Femoral Vein FEMVEIN 95.45 95.45 - - - -Jugular Vein JUGVEIN 78.10 78.10 113.50 113.50 96.25 96.25Double Jugular Vein2 JUGJUGVEIN 158.65 158.65 - - 192.05 192.05Portal Vein PORTVEIN 152.00 152.00 - - - -Portal Vein with T-Tubing PVCTTUBING 190.50 190.50 - - - -Vena Cava (Femoral Vein) VENACAVA-FV 95.45 95.45 - - - -

1 Charles River partners with multiple catheter manufacturers to provide standard and customized catheters. Our standard vascular catheter is made of polyurethane. However, silicone, polyethylene and blended catheters are available upon request. Specific catheters that are able to accommodate automated samplers are also available at an additional cost.2 Infusion using only one of these two catheters (indicated on shipping documentation).*Surgical procedures do not include the price of the animal, shipping, or container charges.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 surcharge per animal for immunodeficient models.


Bile Duct†† BILECANN 172.45 172.45 271.25 271.25 - -Colon3 COLON 152.15 152.15 180.20 180.20 - -Duodenum3 DUODCANN 142.35 142.35 220.40 220.40 - -Ileum3 ILEUM 173.60 173.60 - - - -Intraperitoneal Catheterization IP-CATH 113.10 113.10 130.05 130.05 140.30 140.30Intrathecal Cannulation3 THECALCAN 189.75 189.75 - - - -Jejunum3 JEJUNUM 167.30 167.30 177.50 177.50 - -Stomach (gastric)3 STOMCANN 122.30 122.30 133.30 133.30 - -Subcutaneous Catheter SQCATH 54.40 54.40 90.55 90.55 - -Urinary Bladder3 URIBLADCAN 114.40 114.40 133.30 - - -Uterus - Unilateral3 UTERCATH 122.30 122.30 - - - -

3For infusion only; no sample collection.*Surgical procedures do not include the price of the animal, shipping, or container charges.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 surcharge per animal for immunodeficient models.†† The IACUC surgery protocol requires an extended post-operative holding period, for animal recovery, before shipping.


Angiotensin II Testing for IVC ANG II 90.25 90.25 - - - -Chronic Constriction Injury (CCI) of Sciatic Nerve BENNETT 170.25 170.25 - - - -Bilateral Brain Cannulation4†† BIL-BRAIN 225.45 225.45 279.15 279.15 - -Bilateral Superior Ganglion Denervation GANGLIONBI 85.80 85.80 117.60 117.60 - -Spinal Nerve Ligation (SNL) CHUNG 183.95 183.95 - - - -Intracisternal Cannulation INTRCIST 174.30 174.30 - - - -Intralateral Ventricular Cannulation †† IVC 125.50 125.50 147.90 147.90 - -Intralateral Ventricular Cannulation MRI Compatible†† IVC-MRI 151.55 151.55 - - - -

Intralateral Ventricular Cannulation for Pump Connection†† IVCTUBING 149.25 149.25 - - - -

Intralateral Ventricular Cannulation for Pump Connection MRI Compatible†† IVCTUBINMRI 175.20 175.20 - - - -

Intrathecal Cannulation3 THECALCANN 189.75 189.75 - - - -Microdialysis Probe Implantation4†† UNI-BMICRO 166.50 166.50 - - - -Parkinson’s Model (Chemical-60HDA)†† PARKINSON 205.90 205.90 - - - -Schizophrenia/Epilepsy Model - ** ** - - - -Superior Cervical Ganglion Denervation GANGLION 60.00 60.00 92.25 92.25 - -Unilateral Brain Cannulation4†† UNI-BRAIN 136.35 136.35 154.60 154.60 - -Third Ventricular Cannulation†† 3RDVENTCAN 143.25 143.25 203.20 203.20 - -

3 For infusion only; no sample collection4 Customer provides coordinates.* Surgical procedures do not include the price of the animal, shipping or container charges.** Priced upon request.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 Surcharge per animal for immunodeficient models.†† The IACUC surgery protocol requeires an extended post-operative holding period, for animal recovery, before shipping.



Vascular Catheterizations1

Non-Vascular Catheterizations

Neurological Procedures

Any two vascular catheter procedures may be combined.

Any of these procedures may be combined with a vascular catheter procedure.

Any non-vascular catheter procedure may be combined with a vascular catheter procedure

SURGICAL SERVICES


Abdominal Banding – Hypertension Model†† ABDBAND 82.00 82.00 - - - -Atherosclerosis - Carotid Artery Embolectomy ATHERO-EMB 208.45 208.45 - - - -Left Coronary Artery Ligation†† MYOINFARC 255.65 255.65 - - - -Portal circulation redirected to the vena cava, bypassing the liver PORTCAVSHT 282.90 282.90 - - - -

Thoracic Aortic Banding†† TABAND 139.65 139.65 - - - -Thoracic Aortic Banding - Ascending Aorta†† AATABAND 180.50 180.50 - - - -* Surgical procedures do not include the price of the animal, shipping, or container charges.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 Surcharge per animal for immunodeficient models.†† The IACUC surgery protocol requeires an extended post-operative holding period, for animal recovery, before shipping.


Adrenalectomy ADREX 22.45 22.45 23.60 23.60 - -Adrenal Demedullation ADREXDEMED 37.05 37.05 40.25 40.25 - -Bile Duct Ligation BILEDUCLIG 62.40 62.40 71.35 71.35 - -Castration CASTRATE 21.90 21.90 22.85 22.85 - -Facial Nerve Axotomy - Unilateral FACAXOT 70.75 70.75 - - - -Hepatectomy HEPATEX - - 146.90 146.90 - -Hypophysectomy (Pharyngeal) - Std weights†† HYPOX 62.30 62.30 97.80 97.80 - -Hypophysectomy <75g or >200g†† HYPOX1 93.05 93.05 - - - -Hysterectomy HYSTERX 68.40 68.40 73.20 73.20 - -Nephrectomy – Unilateral NEPHREX 38.15 38.15 40.85 40.85 - -5/6 Nephrectomy – Multiple survival†† 5/6 NEPHREX 124.10 124.10 136.40 136.40 - -Olfactory Bulbectomy OLFACTOREX 123.00 123.00 - - - -Osteoarthritis Model (MIA) †† MIA14 28.70 28.70 - - - -Ovariectomy OVARIEX 21.90 21.90 22.40 22.40 43.45 43.45Pancreatectomy PANCRISX 126.50 126.50 - - - -Parathyroidectomy†† PARATHYROX 46.15 46.15 - - - -Pinealectomy PINEAL 211.50 211.50 - - - -Splenectomy SPLEENX 26.80 26.80 32.10 32.10 - -Splenic Denervation SPLENDNERV 130.60 130.60 - - -Thymectomy THYMEX 48.55 48.55 61.30 61.30 - -Thyroidectomy w/ Parathyroid Reimplant THYROX 49.05 49.05 - - - -Thyroidectomy + Parathyroidectomy THYRO+PARA 47.75 47.75 48.50 48.50 - -Tubal Ligation – Bilateral BITUBALLIG 34.60 34.60 36.45 36.45 - -Tubal Ligation – Unilateral UNTUBALLIG 28.95 28.95 29.85 29.85 - -Ureter Ligation URETERLIG 81.45 81.45 94.00 94.00 - -Vagotomy (Hepatic - standard procedure for mice)†† VAGOX 70.45 70.45 72.35 72.35 - -Vagotomy-Stomach†† VAGOX-STM 70.45 70.45 - - - -Vagotomy (Sub-diaphragmatic - standard procedure for rats)†† VAGOX-SD 70.45 70.45 - - - -

Vasectomy VASEX 26.65 26.65 28.60 28.60 - -

Sham procedures are available upon request.* Surgical procedures do not include the price of the animal, shipping, or container charges.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 Surcharge per animal for immunodeficient models.†† The IACUC surgery protocol requeires an extended post-operative holding period, for animal recovery, before shipping.



A soft tissue procedure may be combined with a vascular catheter procedure.

Soft Tissue Procedures

Cardiovascular Procedures

SURGICAL SERVICES


Blood Pressure Telemetry†† TELEMBP 163.20 163.20 183.25 183.25 170.45 170.45Blood Pressure + Electrocardiograph Telemetry†† TELEMBPECG 199.70 199.70 238.55 238.55 201.60 201.60Blood Pressure + Electroencephalograph Telemetry†† TELEMBPEEG 199.70 199.70 - - - -Electrocardiograph Telemetry†† TELEMECG 137.20 137.20 142.30 142.30 141.95 141.95

Electroencephalograph + Electrocardiograph Telemetry†† EEG/ECG 162.05 162.05 174.40 174.40 - -

Electroencephalograph + Electromyograph Telemetry†† EEG/EMG 169.05 169.05 - - - -

Electroencephalograph + Electroencephalograph + Electromyograph†† EEG/EEG/EMG 289.25 289.25 - - - -

Electromyograph Telemetry †† EMG 137.20 137.20 - - - -Osmotic/Infusion Pump IMPLANT2 61.90 61.90 61.90 61.90 61.90 61.90Pleural Pressure Telemetry†† TELEMPP 231.15 231.15 - - - -Pleural Pressure + Electrocardiograph Telemetry†† TELEMPPECG 280.85 280.85 - - - -Simple Injectable Implant IMPLANT 25.15 25.15 25.15 25.15 25.15 25.15Temperature + Activity Telemetr†† TELEMTA 117.15 117.15 - - - -

* Surgical procedures do not include the price of the animal, shipping, or container charges.† Add $11.25 Surcharge per animal for gas anesthesia. Add $13.50 Surcharge per animal for immunodeficient models.†† The IACUC surgery protocol requeires an extended post-operative holding period, for animal recovery, before shipping.

Item Price**Rent-a-Surgeon 3,549.00Rent-a-Trainer 5,460.00*Pricing does not include travel expenses.


DEVICE IMPLANTS5

Surgical Support

5 Charles River does not stock of any of these items, but will implant them when supplied by customer in factory-direct packaging. Price does not include cost of these devices.


SURGICAL SERVICES

Description Code Price Description Code PriceNEW RapID Tags® (customer supplied tag)** RAPID 5.00 NEW RapID Tags® (customer supplied tag)** RAPID 5.00Avid Brand Identification Chip - Subcutaneous Implant AVIDTRANS 12.10 Avid Brand Identification Chip - Subcutaneous Implant AVIDTRANS 12.10Biomed Brand Identification Chip - Subcutaneous Implant BIOMEDTRNS 12.10 Biomed Brand Identification Chip - Subcutaneous Implant BIOMEDTRNS 12.10Ear Punch EARPUNCH 3.80 Ear Punch EARPUNCH 3.80Ear Tags EARTAGS 3.80 Ear Tags EARTAGS 3.80Somark Labstamp® (mice only) LABSTAMP ID 5.00 Somark Labstamp® (mice only) LABSTAMP ID 5.00Tail Marking TAILMARK 3.60 Tail Marking TAILMARK 3.60Tattoo TATTOO 6.60 Tattoo TATTOO 6.60*Pre-ID™ services do not include the price of the animal, shipping or container charges. *Pre-ID™ services do not include the price of the animal, shipping or container charges.** Charles River can supply the tag and service for $10.50. ** Charles River can supply the tag and service for $10.50.

Description Code Price Description Code PriceGlucose Monitoring GLUCOSE 6.25 Glucose Monitoring GLUCOSE 6.25*Pre-Screening services do not include the price of the animal, shipping or container charges. *Pre-Screening services do not include the price of the animal, shipping or container charges.

Description Code Price Description Code PriceInjection** INJECT 5.35 Injection** INJECT 5.35IP (intraperitoneal) Injection** INJ-IP 5.35 IP (intraperitoneal) Injection** INJ-IP 5.35Subcutaneous Injection** INJ-SUB-Q 5.35 Subcutaneous Injection** INJ-SUB-Q 5.35IP (intraperitoneal) Injection of Pristane (mice only) PRISTANE 3.60 IP (intraperitoneal) Injection of Pristane (mice only) PRISTANE 3.60*Pre-Dosing/Pre-Injection services do not include the price of the animal, shipping or *Pre-Dosing/Pre-Injection services do not include the price of the animal, shipping orcontainer charges. container charges.**Customer-supplied injectable. **Customer-supplied injectable.


Pre-Screening Services*

Pre-Dosing/Pre-Injection Services*

2016 CUSTOMER PRICE



Pre-ID™ Services*

PRECONDITIONED MODELS

www.criver.com GENERAL TERMS & CONDITIONS OF SALE

General Terms & Conditions of Sale (“Terms and Conditions”)Charles River Laboratories, Inc. and its affiliates (“Charles River”) will provide the products (“Products”) and services (“Services”) described in the Charles River invoice, quotation, protocol, or statement of work as applicable (“SOW”) and Charles River’s customer (“Customer”) will purchase the Products and Services pursuant to the specifications contained in the SOW and in accordance with these Terms and Conditions. These Terms and Conditions will also apply to all future purchases of Products and Services by Customer.

1. Binding Character

All sales and/or purchases of Products and Services are (a) governed by these Terms and Conditions and (b) made expressly conditioned upon Customer’s acceptance of these Terms and Conditions.

Customer’s acceptance of delivery of Products or Services will be deemed agreement to the Terms and Conditions.

No other document attempting to negate or otherwise modify the terms hereof, including any purchase order or request for proposal or any deviating or supplementing standard terms and conditions of Customer, will be binding upon Charles River unless expressly agreed to Charles River in writing. Instead these Terms and Conditions, including any special terms and conditions set forth separately as supplemented by any applicable provisions of Applicable Law, shall exclusively govern the sale of Products and Services by Charles River. This also applies if Charles River delivers Products or provides Services despite being aware of conflicting or additional standard terms and conditions of Customer.

2. Provision of the Products and Conduct of the Services

Charles River will adhere to all laws, rules and regulations applicable to the provision of the Products and the conduct of the Services at the place of performance (“Applicable Law”).

If an amendment to the SOW requires additional or different work on the part of Charles River, Charles River may agree to conduct such work and will be paid an amount mutually agreed to by the parties. Deviations from the SOW may be made in an emergency without Customer’s approval, provided that Charles River uses commercially reasonable efforts to obtain Customer’s verbal approval, which will be subsequently confirmed by Customer in writing. The parties acknowledge that during the course of performing the Services in accordance with the SOW, additional costs may be incurred by Charles River as a result of procedural changes, which do not amount to, or require a change in, the SOW, but which are deemed necessary by Charles River to successfully perform the Services, and which could not be foreseen at the time of the preparation of the SOW. If such procedural change occurs, Charles River will advise Customer prior to implementation and solicit Customer’s agreement as to the necessity and additional cost thereof. If Charles River is unable to contact Customer in advance, Customer agrees that in order to maintain the integrity of the Services, Charles River may proceed accordingly, and be entitled to recover such additional costs from Customer upon presentation of an explanation of such procedural changes and the necessity thereof.

3. Restrictions on Use and Breeding

Products will be used by Customer in a safe manner and in accordance with all Applicable Laws. Customer agrees and will ensure that all animals purchased from Charles River, descendants of those animals derived by inbreeding or crossbreeding, including unmodified derivatives of those animals or their descendants (“Models”) will not be: (i) used for any purpose other than the internal research of Customer in compliance with Applicable Law, (ii) bred (for sale or otherwise) or provided to any third party for any use, or (iii) provided to any agent or other third party to provide breeding or other services, unless Charles River provides Customer with prior written authorization. For safety reasons, Customer will not, without the prior written consent of Charles River, return Products or shipping containers to Charles River.

The purchase of any Products conveys to Customer the non-transferable, non-sublicensable, non-exclusive right to internally use the Product and the components of the Products only in research conducted by Customer and specifically in accordance with the SOW. Customer cannot sell or otherwise transfer or make available to a third party the Products or their components or the Services for Commercial Purposes. “Commercial Purposes” means any activity for cash or other consideration including, but not limited to: (1) use of the Products or their components or materials made using the Products or their components in manufacturing, or to provide a service, information or data, or for clinical, therapeutic, diagnostic or prophylactic purposes or (2) resale of the Products or their components or materials made using the Product or its components, except by licensed distributors of Charles River, whether or not resold for use in research. The foregoing limitations are required by Charles River given the nature and sensitivity of the Products and Services provided by Charles River. To the extent that Charles River owns or controls (with the right to sublicense) patent rights or other intellectual property rights applicable to the Products or their intended use, those rights are licensed to Customer on a limited, revocable, non-exclusive, non-transferableand non-sublicensable basis only for the internal uses expressly permitted above and solely for the Products purchased. If Customer fails to comply with the foregoing limitations, in addition to any other remedies available to Charles River, the right of use granted under the preceding sentence will automatically terminate.

4. Compensation

Unless otherwise agreed to by the parties, prices will be as per the price list (if applicable, price of Models is based on highest weight range) on the day of delivery, and they do not include applicable taxes, packaging, insurance or shipment expenses. The price list may be reviewed by Charles River annually. Customer will pay Charles River as set forth in the SOW. All invoices are due and payable thirty (30) days from the date of the invoice without any deductions and Customer agrees to pay all invoices submitted. Customer will not withhold payment, assert a right of retention or set off any counterclaims unless Customer’s counterclaims have been finally adjudicated by a competent court or have been acknowledged by Charles River in writing. All amounts not paid by Customer when due will accrue interest from the applicable due date until paid, at the highest rate permitted under Applicable Law. Charles River may also elect to cease or suspend

the supply of the Products, any work on the Services or withhold required reports or other deliverables if Customer does not make payments when due and payable.

All applicable termination, delay or cancellation fees will be set forth in the SOW.

If in the judgment of Charles River, Customer’s financial condition is precarious or there has been a materially adverse change in Customer’s financial condition, Charles River will have the right to demand payment or other assurances which it deems adequate before providing any Products and Services.

5. Test Article

Customer will provide Charles River with sufficient amounts of compounds, materials, animals, substances, devices and protocols meeting relevant specifications, including health and genetic data (“Test Articles”) with which to perform the Services. Customer will provide Charles River with complete and accurate data to apprise Charles River of the identity, strength, purity, stability, composition or other characteristics, proper storage and safe handling requirements of the Test Articles, including a Material Safety Data Sheet or equivalent documentation. Customer will certify to Charles River that the methods of synthesis, fabrication, or derivation of the Test Article have been documented. All costs associated with shipping the Test Articles to Charles River will be the responsibility of Customer, and Charles River will not be responsible for any loss, damage or destruction of the Test Articles while in transit. All Test Articles and Products used in connection with the Services will remain the property of Customer.

6. Reports

Charles River will keep complete and accurate records of the status and progress of the Services if, and as required by, the SOW. Charles River will furnish a report or data containing information as specified in the SOW. All reports will be prepared in the standard format of Charles River.

Neither Charles River nor Customer will publish any report or data prepared for Customer by Charles River without the prior written consent of the other party, which will not be unreasonably withheld.

If Charles River provides electronic access to the data, records, reports and other documentation and Customer elects to use such electronic access, the use of such electronic access will be governed by Charles River’s standard access terms and conditions which are available on request.

7. Inspections

Upon reasonable advance written notice and during regular business hours, Charles River will permit Customer to visit the Charles River facilities where the Services are performed to monitor Charles River’s performance of the Services, in compliance with Charles River’s biosecurity measures, taking into account Charles River’s business requirements and ensuring an uninterrupted course of business at Charles River’s premises.

Charles River will notify Customer as soon as practical in the event of any regulatory inspection of Charles River’s facilities that directly impact the Services provided to Customer.

8. Ownership

Any inventions, techniques and intellectual property, technology, commercial and industrial secrets, regardless of whether patented or registered, for providing the Products or performing the Services are, and will remain, Charles River’s exclusive property including, but not limited to, present and future documentation, scientific and technical data, test procedures and other information that is owned or licensed by Charles River and is not developed hereunder. Charles River will have the right to use concurrent control data as part of its general historical database. Any data, discoveries or inventions developed or generated, which directly relate to any information or materials provided by Customer hereunder including, without limitation, new data, uses, processes or compositions, will be the exclusive property of Customer. Charles River agrees to assist Customer in securing any patents, copyrights or other proprietary rights in such data, discoveries or inventions, and to perform all acts that may be reasonably required to vest in Customer all right, title and interest in such data, discoveries or inventions, and Charles River will be compensated at its standard rates for such assistance. All costs and expenses associated with establishing Customer’s rights therein will be Customer’s responsibility.

9. Archiving

All reports and supporting documentation resulting from the Services are Customer’s property (“Materials”). Except as otherwise set forth in the SOW, and if requested in writing by Customer, Charles River will retain the Materials for a period of one year following the date of any final report, or for such shorter period as may be required by Applicable Law. At the end of such period, Charles River will contact Customer to determine disposition of the Materials as follows: (a) extended storage of the Materials; (b) return of the Materials to Customer at Customer’s expense or (c) disposal of Materials at Customer’s expense. If Customer requests Charles River to continue to store the Materials and Charles River agrees, the cost for storage of the Materials will continue to be invoiced to Customer at Charles River’s then current rates. If Customer fails to give such instructions, Charles River will notify Customer, and if instructions are not forthcoming within thirty (30) days of said notification, Charles River will have the option of continuing to store the Materials or returning the Materials to Customer at Customer’s expense. Customer will be liable for storage charges until the Materials are returned to Customer. While the Materials are in transit to Customer, all risk of loss or exposure to the Materials will be borne by Customer.

If the Materials require special storage requirements, additional charges for storage will be assessed and invoiced to Customer. Invoices will be issued annually in advance and are due and payable upon receipt.

www.criver.com

GENERAL TERMS & CONDITIONS OF SALE [email protected]

10. Warranties

Customer warrants that it owns all rights, title and interest in the Test Articles furnished to Charles River and the intellectual property related thereto, and that Charles River’s use of the Test Articles does not infringe any third party rights.

Charles River warrants that the Products and Services will conform to the specifications contained in the SOW and Applicable Law. Charles River does not warrant or represent that the results of the Services will be acceptable to any regulatory or governmental agency to which they are presented nor that the results of the Services will enable Customer to further develop, market or otherwise exploit the Test Articles or any other product or service.

THE WARRANTY BY CHARLES RIVER SET FORTH HEREIN IS IN LIEU OF ANY AND ALL OTHER REPRESENTATIONS OR WARRANTIES, EXPRESS, IMPLIED OR STATUTORY INCLUDING, WITHOUT LIMITATION, ANY IMPLIED WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, SUITABILITY OF THE PRODUCTS AND SERVICES FOR CUSTOMER’S PURPOSES, IMPACT OF THE PRODUCTS AND SERVICES ON CUSTOMER’S OPERATIONS, OR NON-INFRINGEMENT OF A PATENT, TRADEMARK OR OTHER INTELLECTUAL PROPERTY RIGHT.

Any claim for breach of this warranty must be made in writing to Charles River within ten (10) business days after the Products are delivered or the completion of Services, after which time the Products or Services will be deemed finally accepted.

Risk of loss and title to the Products will pass to Customer once the Products leave Charles River’s facility or are delivered to a common carrier, as applicable.

11. Limitation of Liability

Charles River will not be liable for penalties or liquidated damages or for special, indirect, consequential punitive, exemplary or incidental damages of any type or kind (including, without limitation, lost profits) regardless of whether any such losses or damages are characterized as arising from breach of contract, breach of warranty, tort, negligence, strict liability or otherwise, even if Charles River is advised of the possibility of such losses or damages, or if such losses or damages are foreseeable.

Charles River’s liability, regardless of the form of action, will be limited to actual and foreseeable damages and will not exceed the total price paid for the Products or Services pursuant to which such liability arises. Charles River will not be liable for any damages arising from, or in connection with, any decision by Customer or any third party to further research, develop or market the Test Articles or any derivative or product or service related thereto, or the use made of the Products, Services or Test Articles derivative or service related thereto.

Subject to the limitations set forth in this Section, if Charles River commits a breach of the warranty set forth above, Charles River’s sole liability, and Customer’s sole remedy will be for Charles River to replace the Products or issue a credit therefore, or conform the work or portion of the Services affected by the breach to the relevant specification.

12. Indemnities

Customer will defend, indemnify, save and hold harmless Charles River and its parent, subsidiaries and affiliates and their respective directors, officers, employees and agents from and against any claims, demands, suits, actions, causes of action, losses, damages, fines and liabilities, including reasonable professional fees (“Claim”) arising out of or in connection with or attributable to (a) the research, development, manufacture, distribution, use, sales or other disposition by Customer, or any distributor, collaborator, Customer, sublicense, representative or agent of Customer, of the Test Articles and/or any other substances upon which the Services were performed or any use made of the Products, or (b) any infringement of any third party’s patent or other intellectual property rights or unauthorized use or misappropriation of its know-how or trade secrets, or (c) Customer’s gross negligence or willful misconduct, or breach of this agreement or (d) personal injury related to contact with the Products during visits to Charles River’s facilities or after delivery of the Products to Customer, and will pay any costs and damages which, by final judgement, after exhaustion of all reasonable appeals, may be assessed against them, provided that Customer is given written notice of the Claims within five (5) days of the date of notice to Charles River and is given information, reasonable assistance and sole authority to defend and/or settle the Claim.

13. Insurance

Each party will have insurance sufficient to cover its interest or potential liabilities hereunder including, but not limited to, worker’s compensation, if applicable, and comprehensive general liability.

14. Confidentiality

In the course of providing the Products or performing the Services, Charles River and Customer may exchange proprietary and confidential information. The parties will identify, in writing, such information as confidential and/or proprietary. If a party intends to disclose confidential information to the other party orally, the disclosing party will (i) alert the other party of the confidential nature of the disclosure prior to the disclosure and (ii) provide written notice to the other party of the confidential nature and contents of such disclosure within ten (10) days of the original disclosure. Each party will use its commercially reasonable efforts to maintain such information in confidence and will employ reasonable and appropriate procedures to prevent its unauthorized publication or disclosure unless required by Applicable Law to disclose such information. Neither party will use the other party’s proprietary and/or confidential information for any purpose other than in performance of this Agreement. The obligations of confidentiality set forth in this Section will survive termination or expiration of this Agreement for a period of five (5) years.

The confidentiality provisions in this Section will not apply to any part of such information, which (i) is known to the receiving party at the time it was obtained from the disclosing party; (ii) is acquired by receiving party from a third party, and such third party did not obtain such information directly or indirectly from the disclosing party under obligation not to disclose; (iii) is or becomes published or otherwise in the public domain other than by violation of this Agreement by the receiving party; (iv) is independently developed by the receiving party without reference to or reliance upon the information provided by the disclosing party; or (v) is required to be disclosed by the receiving party to comply with applicable laws or governmental regulations; provided that the receiving party provides prompt written notice of such disclosure to the disclosing party and cooperates with the disclosing party’s reasonable and lawful actions to avoid and/or minimize the extent of such disclosure.

15. Termination

Unless otherwise specified in the SOW, Customer will have the right to terminate the SOW at any time without cause upon thirty (30) days prior written notice to Charles River. In the event of such termination, Charles River will be paid for all Products provided or Services rendered through the effective date of termination, together with any additional expenses incurred in connection with the shutdown of the Services including, without limitation, any irrevocably committed costs and any cancellation or termination fee set forth in the SOW.

Either party may terminate these Terms and Conditions or SOW, as applicable, at any time upon thirty (30) days prior written notice to the other party, for material breach of the Terms and Conditions by the other party if such breach is not remedied to the non-breaching party’s reasonable satisfaction within the thirty (30) day notice period.

Upon termination, neither party will have any further obligations, except that (i) the liabilities accrued through the date of termination and (ii) the obligations which by their terms survive termination, including the applicable confidentiality, record keeping, regulatory compliance, intellectual property and indemnification provisions of these Terms and Conditions, will survive termination.

16. Force Majeure

Except with respect to the payment of any amount due hereunder, neither party will be considered in default of the performance of any obligation hereunder to the extent that the performance of such obligation is prevented or delayed by fire, flood, earthquake, hurricane, explosion, disease, contamination, strike, acts of terrorism, war, insurrection, embargo, government requirement, civil or military authority, animal activism, act of God, or any other event, occurrence or condition which is not caused, in whole or in part, by that party, and which is beyond the reasonable control of that party.

17. Governing Law and Dispute Resolution

These Terms and Conditions and any dispute arising from or in connection with the sale of the Products and/or Services are governed by, and will be construed in accordance with, the laws of Delaware, excluding the United Nations Convention on the International Sale of Goods and without regard to any choice of law principle that would dictate the application of the law of another jurisdiction.

The parties will attempt to resolve through negotiations any controversy, claim, or dispute arising out of or in connection with these Terms and Conditions or its validity. If the negotiations are not successful, the controversy, claim, or dispute will be submitted to third-party mediation upon terms reasonably acceptable to the parties. If such claim, controversy or dispute is not resolved through mediation, upon written demand of either party, the claim, controversy or dispute will be submitted to arbitration. Such arbitration will take place in Boston, Massachusetts, will be conducted in English, and will proceed in accordance with the United Nations Commission on International Trade Law Arbitration Rules in force from time to time. A record and transcript of the proceedings will be maintained. Any award will be made in writing and in reasonable detail, setting forth the findings of fact and conclusion of law supporting the award. The determination of a majority of the panel of arbitrators will be the decision of the arbitrators, which will be binding regardless of whether one of the parties fails or refuses to participate in the arbitration. The arbitrators will decide on the recovery of the costs of the arbitration, except expert and attorneys’ fees.

18. Miscellaneous

All notices from one party to the other will be in writing. Notices will be sent by internet transmission, overnight courier, or certified mail, return receipt requested. All notices will be effective upon receipt.

The business relationship of Charles River to Customer is that of an independent contractor and not of a partnership, joint venture, employer, agent or any other kind of relationship.

These Terms and Conditions, and the rights and obligations hereunder, may not be assigned or transferred by either party without the prior written consent of the other party.

These Terms and Conditions, together with the SOW, set forth the entire agreement and understanding between the parties, superseding any and all previous statements, negotiations, documents, agreements and understandings, whether oral or written, as to the subject matter hereof.

In the event that any one or more of the provisions contained in these Terms and Conditions is held to be invalid, illegal or unenforceable in any respect, that invalidity, illegality or unenforceability will not affect any other term or condition, and all other terms and conditions will remain in full force and effect.

19. Intellectual Property

Charles River® and Charles River Laboratories® are registered trademarks of Charles River Laboratories, Inc. VAF/Plus®, VAF/Elite®, BlastoKit®, CD®, CD-1®, CFW®, Gnoto-safe®, SHO®, THE POUND MOUSE®, Multiplexed Fluorometric ImmunoAssay® (MFIA®), I•CRYO®, EZ-Spot®, Laboratory Testing Management® and MAX-BAX® are registered trademarks of Charles River Laboratories, Inc. CDF™, CF-1™, EAD™, PRIA™, Sew Easy™, ICM™ and LTM™ are trademarks of Charles River Laboratories, Inc. The SourceSM is a service mark of Charles River Laboratories, Inc. Sprague Dawley® is a registered trademark of Harlan Sprague Dawley, Inc., Indianapolis, IN. SD™ is a Harlan Sprague Dawley trademark. Fox Chase SCID® is a registered trademark of the Fox Chase Cancer Center. Fox Chase CB17™ is a trademark of the Fox Chase Cancer Center. HydroGel™ is a trademark of ClearH2O®. Immortomouse® is a registered trademark of the Ludwig Institute for Cancer Research. TARGATT™ is a trademark of Applied StemCell. Polymerase Chain Reaction (PCR) analysis is performed pursuant to licensing arrangements with Roche Molecular Systems, Inc. and The Perkin-Elmer Corporation. Microsatellite analysis is performed pursuant to licensing arrangements with the Marshfield Clinic. Purina #5008 is a trademark of Nestle Purina Petcare Company. Research Diets is a trademark of BioDAQ®. genOway® is a registered trademark of genOway S.A., Lyon, France. OpenArray® is a registered trademark of Biotrove, Inc. RODAC™ is a trademark of Becton, Dickinson and Company. TaqMan® is a registered trademark of Roche Molecular Systems, Inc. © Charles River Laboratories, Inc., 2016.

20. Language

The parties acknowledge that they have required that the Terms and Conditions, as well as all documents, notices and legal proceedings executed, given or instituted pursuant to or relating directly or indirectly hereto, be drawn up in English.


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