Sunday October 15th, 2017. Please note: separate registration needed Pre-congress interactive HOT TOPIC DOHaD 2017 Workshops Sunday, October 15th DOHaD2017
Training Workshop
Epigenetics and DOHaD Room: Van Weelde Time 9:00 - 17:00
DOHaD2017 / LifeCycle Project Training Workshop
Hot topics in developmental epidemiology Room: Van der Vorm Time 9:00 - 17:00
DOHaD2017 Training Workshop
New strategies for interventions in early life Room: Ruys Time 9:00 - 17:00
DOHaD2017 / Sophia Children’s Hospital Training Workshop
Fetal and neonatal care from DOHaD perspective Room: Van Beuningen Time 9:00 - 17:00
Bastiaan T. Heijmans, Leiden University Medical Center, Leiden, the Netherlands
Sarah Kimmins, McGill University, Montreal, Canada
Pre-congress workshop 2 (PW2) Topics Basic principles of
longitudinal life course modeling approaches
Approaches for individual participant data meta-analyses
Dealing with loss to follow up and selection bias
Principles of mediation analyses
Approaches for causal inference
Faculty Lorenzo Richiardi,
University of Turin, Italy Susana M. Santos, Erasmus
MC, Rotterdam, Netherlands,
Debbie A. Lawlor, University of Bristol, United Kingdom
Kate Tilling, University of Bristol, United Kingdom
Pre-congress workshop 3 (PW3) Topics Basic principles of
intervention studies Specific challenges related
to intervention studies in the field of DOHaD research
Design of interventions and their trials in clinical group and populations
Implementation of findings Faculty Mary Barker, University of
Southampton, Southampton, United Kingdom
Romy Gaillard, Erasmus MC, Rotterdam, the Netherlands
Hans B. van Goudoever, Free University Medical Center Amsterdam, Amsterdam, the
Pre-congress workshop 4 (PW4) Topics Preconception and
embryonic care strategies in patients / populations
Novel embryonic and placental imaging
Perinatal transition and hypoxia
Fetal and neonatal lung development and long term impact
Population health strategies for pregnant women and children
Faculty Liesbeth Duijts, Erasmus
MC, Rotterdam, the Netherlands
Evelien van Meel, Erasmus MC, Rotterdam, the Netherlands,
Jenna Morrison, School of Pharmacy and Medical Sciences, University of South Australia
Stephanie London, NIEHS, Research Triangle Park, USA
Joyce van Meurs, Erasmus MC, Rotterdam, the Netherlands
Susan Ozanne, University of Cambridge, United Kingdom
Robert A. Waterland, Baylor College of Medicine, Houston, USA
Nicholas Timpson, University of Bristol, United Kingdom
Netherlands Berthold Koletzko,
Ludwig-Maximilians-Universität München, Germany
Lucilla Poston, King’s College London, London, United Kingdom
Tessa Roseboom, Amsterdam Medical Center, Amsterdam, the Netherlands
Chittarnyan S. Yajnik, King Edward Memorial Hospital Research Centre, Pune, India
Irwin K.M. Reiss, Erasmus MC, Rotterdam, the Netherlands
Melek Roussian, Erasmus MC, Rotterdam, the Netherlands
Eric A.P. Steegers, Erasmus MC, Rotterdam, the Netherlands
John Wright, Bradford Teaching Hospitals, Bradford, United Kingdom
Monday October 16th, 2017 DOHaD2017 Day 1
Monday, October 16th
Grote Zaal Arcadis Zaal Eduard Flipse Zaal
Jurriaanse Zaal Van Cappellen Zaal
Willem Burger Zaal
Van Weelde Zaal
07:00 - 08:30 Registration
08:30 – 10:30 Plenary session PL1.1 Opening session and the Dutch DOHaD Experience Chairs: V. Jaddoe / L. Poston 8:30 Welcome V. Jaddoe/ Dean, Rotterdam 9:00 DOHaD in 2017 M. Hanson, Southampton 9:30 What did we learn from historical cohort studies T. Roseboom, Amsterdam 10:00 Preconception and embryonic origins of health E. Steegers, Rotterdam
10:30 – 11:00 Coffee break
11:00 – 12:30 Parallel session PA1.1 Endocrine programming Chairs: S. Matthews / R. Peeters 11:00 Stress, glucocorticoids and the developing brain S. Matthews, Toronto
Parallel session PA1.2 Pregnancy interventions Chairs: L. Poston / J. Wright 11:00 Pregnancy interventions: where are we? L. Poston, London
Parallel session PA1.3 Epigenetics Chairs: R. Waterland / B. Heijmans 11:00 Early nutritional influences on metastable epialleles associated with human disease
Parallel session PA1.4 Kidney outcomes Chairs: V. Luyckx / J. Ingelfinger 11:00 Early kidney development and later life consequences V. Luyckx, Zürich
Parallel session PA1.5 DynaHealth Consortium Chairs: M. Jarvelin / S. Sebert 11:00 Lifecourse origins of healthy ageing S. Sebert, Oulu
11:20 A little less association, a little more action: lessons from an experimental birth cohort J. Wright, Bradford Submitted abstracts (8 minute orals) 91 634 53 412 662
R. Waterland, Houston 11:20 Embryo selection and epigenomic signals of prenatal adversity B. Heijmans, Leiden Submitted abstracts (8 minute orals) 406 51 547 113 707
11:20 Early childhood: A critical period for kidney function throughout life J. Ingelfinger, Boston Submitted abstracts (8 minute orals) 13 421 491 343 307
11.20 Prenatal depressive symptoms and offspring brain morphology H. Baameur – El Marroun, Rotterdam Submitted abstracts (8 minute orals) 318 570 143 589 631
12:30 – 12:45 Lunch break
12:40 – 13:40 Lunch meeting LM1.1 Trainee lunch workshop: How to write a successful grant B. Koletzko, Munich Coordinator EU-FP7 Early Nutrition Project
Lunch meeting LM1.2 Slam Session Maternal and fetal health Chairs: E. Steegers / S. Matthews Submitted abstracts (4 minute orals) 497 509 14 260 311 236 776 772 130 89 454
Lunch meeting LM1.3 DOHaD Australia and New Zealand Symposium Chair: B. Mulhauser Submitted abstracts (8 minute orals) 830 831 832 833 844 535
Lunch meeting LM1.4 DOHaD Africa Symposium Chair: S. Norris Submitted abstracts (8 minute orals) 804 233
13:50 – 14:20 Jurriaanse kwartier Posters / poster walks (PO1) PO1.1 Adiposity - Early life factors PO1.2 Cardio-metabolic health - Growth and long-term effects PO1.3 Epigenetics - Growth and cardio-metabolic health PO1.4 Gestational diabetes PO1.5 Respiratory and atopic disease PO1.6 Metabolomics and Circadian rhythm
PO1.7 Neurodevelopment - Early life exposures PO1.8 Nutrition - Metabolic health, socio-economic and behavioural factors PO1.9 Nutrition - micronutrients PO1.10 Population health
14:20 – 15:30 Parallel session PA1.6 Genetics of DOHaD Chairs: N. Timpson / R. Freathy 14:15 Mendelian randomisation in a DoHaD context: what does this mean? N. Timpson, Bristol Submitted abstracts (8 minute orals) 173 573 458 294 273
Parallel session PA1.7 Biological clock Chairs: G. van der Horst/ I. Reiss 14:15 Pre- and perinatal circadian disturbance as a later-life health risk factor G. van der Horst, Rotterdam Submitted abstracts (8 minute orals) 747 622 64
Parallel session PA1.8 Environmental stressors Chairs: M. Vrijheid / L. Trasande 14:15 DOHaD and the early life exposome M. Vrijheid, Barcelona Submitted abstracts (8 minute orals) 768 88 410 445 809
Parallel session PA1.9 Early origins of cancer and rare diseases Chairs: S. Mahabier / T. Roseboom 14:15 Early-life factors and cancer development S. Mahabier, Bethesda Submitted abstracts (8 minute orals) 147 146 415 213 754
Parallel session PA1.10 Early nutrition Chairs: K. Godfrey / H. Demmelmair Submitted abstracts (8 minute orals) 92 197 678 478 171 459 7
15:30 – 16:00 Coffee break
16:00 – 17.30 Plenary session PL1.2 Mechanistic studies in DOHaD Chairs: N. Timpson / J. Felix 16:00 Environmental programming of the heritable sperm epigenome S. Kimmins, Montreal 16:30 Programming by maternal over-nutrition: a developing obesity crisis S. Ozanne, Cambridge 17:00 Genetics of birth weight and later life
diseases R. Freathy, Exeter
17:40 – 19:00 Parallel session PA1.11 Experimental fetal and neonatal models Chairs: J. Morrison/ I. Reiss 17:45 Fetal cardiac and lung responses to chronic hypoxia J. Morisson, Adelaide 18:00 Consequences of fetal and neonatal adaptation to a hypoxic environment I. Reiss, Rotterdam Submitted abstracts (8 minute orals) 630 708 28 628
Parallel session PA1.12 Folate and other nutrients Chairs: C. Yajnik/ R. Steegers- Theunissen 17:45 Vitamin B12 and folate studies in pregnancy in India. C. Yajnik, Pune 18:00 The impact of periconception folic acid on reproduction, care and health. R. Steegers-Theunissen, Rotterdam Submitted abstracts (8 minute orals) 339 612 356 666
Parallel session PA1.13 Maternal obesity and gestational disorders Chairs: B. Koletzko/ R. Gaillard Submitted abstracts (8 minute orals) 349 223 202 194 734 136 579 202
Parallel session PA1.4 Obesity and cardiovascular risk Chairs: N. Modi / A. Marcus de Andrade Paes 17:45: Neonatal adiposity: determinants and consequences for later health, N. Modi, London Submitted abstracts (8 minute orals) 186 471 125 472 201 26
Parallel session PA1.15 HeLTI Symposium Chair: N. Rollins
19:00 – 20:00
20:00 – 22:00 Rotterdam Bridge Run
Tuesday October 17th ,2017 DOHaD2017 Day 2
Tuesday, October 17th
Grote Zaal Arcadis Zaal Eduard Flipse Zaal Jurriaanse Zaal Van Cappellen Zaal Willem Burger Zaal
Van Weelde Zaal
08:00 - 08:30 Welcome
08:30 – 10:30 Plenary session PL2.1 Nutrition, growth and adiposity in the first 1000 days Chairs: P. Gluckman / S. Norris 8:30 Nutrition and the first thousand days: maternal and prenatal interventions Z. Bhutta, Toronto 9:00 Potential for postnatal nutritional interventions B. Koletzko, Munich 9:30 Early growth patterns and childhood adiposity V. Jaddoe, Rotterdam 10:00 Maternal nutrition and metabolic outcomes in the offspring Y.S. Chong, Singapore
10:30 – 11:00 Coffee break
11:00 – 12:30 Parallel session PA2.1 Placental programming Chairs: R. Lewis / G. Desoy 11:00 Placental adaptations and offspring outcomes R. Lewis, Southampton
Parallel session PA2.2 Early environment Chairs: S. Prescott / P. Meijer 11:00 Biodiversity and microbes: Ecological solutions to the human health crisis S. Prescott, Perth 11:20 The role of
Parallel session PA2.3 Mental health outcomes Chairs: C. Stoltenberg / M. Meaney 11:00 Determinants of autism spectrum disorders C. Stoltenberg, Bergen 11:20 Perinatal pathways to psychopathology
Parallel session PA2.5 Later-life interventions to reverse/compensate for effects of early life adversity Symposium Chair: K. Godfrey
Parallel session PA2.6 Environment and DOHaD Chairs: J. Sunyer / M. Guxens Submitted abstracts (8 minute orals) 447 653 5 60
Parallel session PA2.7 LifeCycle and ECHO Networks Chairs: M. Gillman / V. Jaddoe 11:00 Environmental influences on child health outcomes (ECHO)- NIH project M. Gillman, Rockville
11:20 Placental nutrient transfer adaptations G. Desoy, Graz Submitted abstracts (8 minute orals) 306 363 496 350
human milk in early nutrition programming P. Meier, Chicago Submitted abstracts (8 minute orals) 651 536 355 8 55
M. Meaney, Montreal Submitted abstracts (8 minute orals) 552 70 200 34 117
84 274 276 341 732
11:20 EU Child Cohort Network - LifeCycle Project V. Jaddoe, Rotterdam Submitted abstracts (8 minute orals) 538 577 504 49
12:30 – 12:45 Lunch break
12:40 – 13:40 Lunch meeting LM2.1 Trainee lunch workshop: How to make sure your research has great impact M. Hanson, Southampton President DOHaD Society
Lunch meeting LM2.2 Slam session Fetal and childhood outcomes Chairs: E. Steegers / C. Power Submitted abstracts (4 minute orals) 310 238 599 682 242 348 380 396 424 426 435 275
Lunch meeting LM2.3 Abbott Business meeting Industry meeting
Lunch meeting LM2.5 DOHaD Canada Business meeting Chair: D. Sloboda
Lunch meeting LM2.6 Slam session Studies from developing countries Chairs: C. Fall / S. Norris Submitted abstracts (4 minute orals) 291 302 319 826 245 650 337 576 556 699 414
Lunch meeting LM2.7 Slam session Social inequalities Chairs: Z. Bhutta / Y.S. Chong Submitted abstracts (4 minute orals) 676 4 748 711 289 423 649 719 562 528 661
13:50 – 14:20 Jurriaanse kwartier Posters / walks (PO2) PO2.1 Adiposity – Life course PO2.2 Cardiometabolic health - Nutrition PO2.3 Epigenetics – Environmental exposures and neurodevelopment PO2.4 Pregnancy complications and prematurity PO2.5 Mental health and socio-economic factors PO2.6 Environmental exposures PO2.7 Neurodevelopment – Pregnancy and growth PO2.8 Nutrition – Growth and cardiovascular health PO2.9 Embryonic, fetal and placental health PO2.10 Endocrine health
14:20 – 15:30 Parallel session PA2.9 Bone health and osteoporosis Chairs: C. Cooper / N. Harvey 14:15 Early origins of osteoporosis C. Cooper, Southampton Submitted abstracts (8 minute orals) 31 601 615 602 19
Parallel session PA2.10 Early growth and adiposity Chairs: Y.S. Chong / S. Santos Submitted abstracts (8 minute orals) 127 299 237 50 428
Parallel session PA2.11 DSM Business meeting Industry meeting
Parallel session PA2.12 Reproduction outcomes Chairs: M. Sirard / R. Steegers-Theunissen 14:15 The effect of culture on embryo’s DNA methylation and postnatal phenotype M. Sirard, Québec Submitted abstracts (8 minute orals) 822 633 525 96 709
Parallel session PA2.13 How to turn your cohort into an intervention study Symposium Chair: M. Barker
Parallel session PA2.14 Pregnancy and Childhood Epigenetics Consortium Chairs: J. Felix / S. London 14:15 Epigenome-wide association studies in the Pregnancy And Childhood Epigenetics Consortium J. Felix, Rotterdam 14:25 Maternal smoking in pregnancy and offspring methylation S. London, Research Triangle Park Submitted abstracts (8 minute orals) 76 317 338 427 741
Parallel session PA2.15 Environmental chemicals Chairs: L. Trasande / M. Casas 14:15 Synthetic chemical exposures in early life as obesogens and metabolic risks L. Trasande, New York Submitted abstracts (8 minute orals) 29 94 59
15:30 – 16:00 Coffee break
16:00 – 17:30 Plenary session PL2.2 Global population impact Chairs: M. Hanson / D. Sloboda 16:00 The vicious cycle of pregnancy induced complications and NCDs; it all starts in utero - FIGO GLOBAL VISION C. Purandare, Mumbai 16:30 DOHaD – addressing the science-policy nexus P. Gluckman, Auckland 17:00 Interaction between infection and obesity and gestational diabetes during pregnancy S. Norris, Johannesburg
17:40 – 19:00 Parallel session PA2.17 DOHaD Trainees Meeting Chairs: A. Bansal / S. Feuer
Parallel session PA2.18 Nutricia Research Symposium Industry-sponsored symposium
20:00 – 22:00 DOHaD Dinner Disco Dance Party in the Sky
Wednesday October 18th ,2017 DOHaD2017 Day 3
Wednesday, October 18th
Grote Zaal Arcadis Zaal Eduard Flipse Zaal Jurriaanse Zaal Van Cappellen Zaal
Willem Burger Zaal
Van Weelde Zaal
08:00 - 08:30 Welcome
08:30 – 10:00 Parallel session PA3.1 Early origins of aging Chairs: M. Järvelin / A. Hofman 8:30 Life-course paths to metabolic health M. Järvelin, London/Oulu 8:50 Developmental origins of aging: An epidemiological perspective A. Hofman, Boston Submitted abstracts (8 minute orals) 145 546 543 618 596
Parallel session PA3.2 Specific nutrients Chairs: N. Harvey / R. Gaillard 8:30 Gestational vitamin D supplementation and offspring bone development: translation from observation to intervention N. Harvey, Southampton 8:50 Influence of free fatty acids on maternal and child health R.Gaillard, Rotterdam Submitted abstracts (8 minute orals) 24 477 183 170
Parallel session PA3.3 Innovative DOHaD experiments Chairs: T. Plösch / D. Sloboda 8:30 Novel animal models of placental dysfunction in DOHaD research T. Plösch, Groningen 8:50 Early life impacts on reproductive programming: effects in female ovarian development and function D. Sloboda, Hamilton Submitted abstracts (8 minute orals) 730 386 361 526 65
Parallel session PA3.4 Maternal gestational exposures Chairs: D. Lawlor/ E. Steegers 8:30 Maternal gestational exposures and offspring cardio-metabolic health D. Lawlor, Bristol Submitted abstracts (8 minute orals) 9 578 640 131 149 433
Parallel session PA3.5 DOHaD and Society: Responsibility, Participation and Public Health Symposium Chair: M. Hanson
Parallel session PA3.6 Maternal and paternal health Chairs: M. Barker / S. Matthews Submitted abstracts (8 minute orals) 456 805 278 286 52 722 442 632 687
Parallel session PA3.7 Infant nutrition Chairs: H. van Goudoever / Y.S. Chong 8:30 Optimal nutrition for preterm born infants H. van Goudoever, Amsterdam Submitted abstracts (8 minute orals) 739 607 591 740 498
10:00 – 10:30 Coffee break
10:30 – 12:00 Parallel session PA3.9 New intervention strategies Chairs: M. Barker/ S. Shaheen 10:30 Designing complex behaviour change interventions M. Barker, Southampton 10:50 Shortcuts to randomised evidence: Using existing trials in early life for follow-up studies
Parallel session PA3.10 Early origins of asthma Chairs: L. Duijts / K. Bønnelykke 10:30 Early risk factors for childhood respiratory morbidity L. Duijts, Rotterdam 10:50 Fatty acids in pregnancy and childhood asthma) K. Bønnelykke, Copenhagen
Parallel session PA3.11 Brain and neurodevelopment Chairs: J. Sunyer / H. Tiemeier 10:30 Traffic air pollution, APOE e4 status and neurodevelopment in school children J. Sunyer, Barcelona 10:50 Early brain development and childhood cognition H. Tiemeier, Rotterdam
Parallel session PA3.12 Analytical approaches in DOHaD Chairs: K. Tilling / L. Richiardi 10:30 Longitudinal models to examine changes in exposure K. Tilling, Bristol Submitted abstracts (8 minute orals) 523 129 515
Parallel session PA3.13 Metabolon Business Meeting Industry meeting
12:10 – 13.10 Lunch meeting LM3.1 Trainee lunch workshop: How to write a paper for a high impact journal J. Ingelfinger, Boston Deputy Editor New England Journal of Medicine
Lunch meeting LM3.2 Slam Session Neurodevelopment Chairs: H. El Marroun / M. Meaney Submitted abstracts (4 minute orals) 819 176 34 326 335 522 679 80 580 588 150 473
Lunch meeting LM3.3 DOHaD AGM Chairs: M. Hanson / D. Sloboda
Lunch meeting LM3.4 Slam Session Cardiovascular development Chairs: A. Fraser / K. Godfrey Submitted abstracts (4 minute orals) 624 581 251 566 162 437 696 301 174 595 374 596
13:50 – 14:20 Jurriaanse kwartier Posters / walks (PO3) PO3.1 Adiposity – Nutrition and physical activity PO3.2 Genetics PO3.3 Reproduction and preconception PO3.4 Maternal obesity and physical activity PO3.5 Microbiome PO3.6 Neurodevelopment - Nutrition PO3.7 Neurodevelopment – Population health PO3.8 Nutrition PO3.9 Interventions PO3.10 Growth and aging
14:20 – 16:00
Plenary session PL3.1 DOHaD Past, Present and Future Chair: Z. Bhutta / S.Ozanne 14:20 DOHaD Career awards 15:20 DOHaD Junior researcher awards 15:30 DOHaD Journal M. Ross, Los Angeles 15:40 DOHaD 2019 J. Bertram, Melbourne 15:50 Closure V. Jaddoe, Rotterdam M. Hanson, Southampton 16:00 Farewell
