UROGENITAL SYSTEM

LAB -1

6 yr old boy, generalized edema, heavy

proteinuria. Diagnosis????

Minimal change disease

•Prevalence in

children? M/C NS

•LM findings?none

•IF findings? none

•EM findings?

Effaced podocyte

foot processes

34 yr old female, generalized edema,

protinuria and microscopic hematuria.

Diagnosis ????

Focal and segmental glomerulosclerosis (FSGS)

•Prevalence in

adults? m/c NS in

adults

•LM findings?

Segmental sclerosis

affecting some of

the glomeruli.

• IF findings?

negative

56 yr old

man with

medical

history of

colon

cancer.

Recent

onset

Nephrotic

syndrome.

EM picture

of

glomeruli.

Diagnosis

?????

Membraneous glomerulopathy

•Types? 1ry and

2rdy

•Causes of 2dry?

•Drugs

• heavy metals

•Infections

•malignancy

Black arrows??????

Rapidly Progressive (Crescentic)

Glomerulonephritis

???????

MPGNWhat type of

special stain is

this?

What is the

characteristic

light microscopic

finding you see

here.

???????

•Causes ?

Congenital and

acquired

•Consequences

? Chronic renal

failure if not

treated early

hydronephrosis

????

•what type of

renal cysts do

you see?

• what is the

clinical

significance?

?????•what is the

clinical

significance?

• name genetic

abnormalities.

??????

•what is the

type of this

tumor?

•Name a genetic

predisposing

factor for it?

•what is this

tumor?

•genetic

mutations?

•age group of

patients?

????

•Types?

•morphology ?

• name a

paraneoplastic

syndrome

associated with

this tumor.

?????

?????

Type?

Risk factors?