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US EPA-Pesticides; Dichlorvos | US EPA ARCHIVE … · TABLE t VALUE (0.01 (2), 6) ... 2 0.746 0.850...

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1. CHEMICAL: ' DDVP-Technical PC Code No.: 084001

2. TEST MATERIAL: DDVP Technical Grade; Lot No. 402010; Purity: 98.0% and I~C-DQVP technical Grade; Lot No. 3048-221 ; Specific activity: 1 8.51 8 m~i lmrno l .

3. CITATION Authors: G.S. Ward and J.W. Davis

1

Title: DDVP Technical Grade: Chronic Toxicity to the Mysid (fisidopsis bahia) Under Flow-Through - Conditions.

Studv Completion Date: August 5, 1996 Laboratorv: Toxikon Environmental Sciences

Sponsor: AMVAC Chemical Corporation, Los Angeles, CA Latioratorv Report ID: J9407006a

MRID No.: 438543-01 DP Barcode: D222024

4. ogist, EEB, EFED

Date: 7 /*3i/9 !, 5. APPROVED BY: Les Touart, Head of Section (I), EEB, EFED

Signature: L Date: ?($kc . ,

6. STUDY PARAMETERS

- - - Age of Test -Organism: - < 2 4 hc;, a TI? Definitive Test Duration-:- L8 days

Study Method: Flow-through Type of Concentrations: Mean measured

i

7. CONCLUSIONS: >

I

Results Synopsis NOEC: 1.48 pg ai/L LOEC: 3.25 pg ai/L MATC: 2.1 9 pg ai/L

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DP Barcode: D222024 MRID No.: 438543-01

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Parental Acclimation 1 ) Parental stock must be maintained separately from the brood culture in dilution water and under test conditions. 2) ~ ~ s i d k should be in good health:

Parental Acclimation Period At least 1 4 days -

Chamber Location: Treatments should be randomly assigned to test chamber locations.

Duration of the Tqst: A mysid test must not be terminated before 7 days past the median time of I "' brood release in the control treatment.

Brood Stock: Test started with mysids: 1 ) from only one brood stock or 2) from hr~-og stoc,k which has not

{ T oi&iTk so:;ai.n~a~urit~ or had been ' --

maintained for > 1 4 days in a laboratory with same food, water, temperature, and salinity used in the test.

T i - * * "

Reporpqd dx t n f ~ h a t i o n Li

The culture system was designed to collect post-larval mysids as soon as they were released from the female: However, 12 and 1 4 days prior to test initiation, the culture system was supplemented with parental mysids acquired from Aquatic BioSystems, lnc.

No diseases observed, nor disease treatments were administered to either adult culture or post-larvae population of mysids.

Not reported

Randomly assigned

I

NIA

,

Test had t w o brood stocks, the -

second brood stock was introduced on days 12 and 1 4 of the prior to test initiation.

- -- - -

DP Barcode: D222024 MRlD No.: 438543-01

Test Temperature: The test temperature during the 32- 1 ) Mean measured temperature for day total exposure ranged from 25.7 '

each chamber at test termination to 28.7-C with a mean and standard should be within 1 -C of selected test deviation of 27.0 & 0.7tC.

2) Each individual measured I

temperature, must vvi:hin 3TC sf the _ r &. - -

mean of the time-weighted averages. 3) For mysid shrimp, 27-C is ,

recommended. 4) Whenever temp. is measured concurrently in more than one test chamber the highest & lowest, temp. must not differ by more than 2 4 .

Photoperiod: Recommend 16Ll8D.

Dosing Apparatus: 1 ) Definitive exposure was conducted 1 ) Intermittent flow proportional under flow-through conditions in a diluters or continuous flow serial modified proportional vacuum-siphon diluters should be used. diluter (Mount and Brungs 1967). 2) A minimum of 5 toxicant concentrations 2) 0.81, 1.63, 3.25, 6.65, and 13.0 3) with a dilution factor not greater P ~ / L . than 0.5 and controls should be used.

3) 50% dilution and equal solvent concentration in all test concentiations.

Toxicant Mixing: Not Reported. 1) Mixing chamber is recommended but not required; 2) Aeration should not be used for

3) It must be demonstrated that the test solution is completely mixed before intro. into the test system; 4) Flow splitting accuracy must be

/

6

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DP Barcode: D222024 MRlD No.: 438543-01

Chemical Svstem:

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Concentrations: I

1) ~ i n i m b m of 5 concentiations and a controfall replicated. plus solvent control if appropriate. 2) Toxicant conc. must be measured in one tank at each toxicant level every week. 3) One concentration must, adversely. affect a life stage and one concentration must not affect any life stage. 4) The measured conc. of the test material of any treatment should be at least 50% of the time-weighted average measured conc. for > 10% of the duration of the test. 5) The measured conc. fot any treatment level should not be more than 30% higher than the time- weighted average measured conc. for more than 5% of the duration of the test.

solvents: 1) Should not exceed 0.1 mllL in a f low-through system. 2) Following solvents are acceptable: tristhylene glycol. methanol, acetone, ethanol.

1) Control. Solvent Control (DMF), 0.81. 1.63. 3.25. 6.5, 13.0 pg "c- equivalents1L

, 2) Water samples were collected from the controls and each DDVP Technical Grade replicate test chamber on test days 0. 7, 14, 21, and 28.

4) Measured concentrations ranged from 84% (day 0) to 102% (mean) of the nominal concentrations.

',

Triethylene glycol (TEG) solvent at 5.66 pI/L I

, --

"- - -*

UMBER OF OFFSPRING PER FEMALE REPRODUCTIVE DAY ile: C:\ACTIONS\DDVP\MYSID~ Transform: NO TRANSFORM -

ANOVA TABLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

ANOVA TABLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

SOURCE DF SS MS F . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Between 5 1 1 . 0 5 8 2 . 2 1 2 1 0 . 1 4 7

Wi th in (Error) 2 2 4 . 7 8 7 0 . 2 1 8 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Total 2 7 1 5 . 8 4 5 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Critical F value = 2 . 6 6 ( 0 . 0 5 , 5 , 2 2 ) Since F > Critical F REJECT Ho:A11 groups equal

NUMBER OF OFFSPRING PER FEMALE REPRODUCTIVE' DAY File: C:\ACTIONS\DDVP\MYSIDl Transform: NO TRANSFORM

TUKEY method of multiple comparisons . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

GROUP TRANSFORMED ORIGINAL 0 0 0 0 0 0

GROUP IDENTIFICATION MEAN MEAN 6 5 1 4 2 3 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

6 1 3 . 0 0 . 2 0 3 0 . 2 0 3 \ 5 6 . 6 3 1 . 5 0 8 1 . 5 0 8 * \ 1 GRPS 1 & 2 POOLED 1 . 6 5 0 1 . 6 5 0 * . \ 4 3 . 2 5 1 . 7 4 5 1 . 7 4 5 * . . \ '

2 0 . 7 4 6 2 . 1 0 5 2 . 1 0 5 * . . . \ 3 1 . 4 8 2 . 3 2 3 2 . 3 2 3 * . . . . \

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . * = significant difference ( p = 0 . 0 5 ) . = no,significant difference Tukeyvalue(6,22)= 4 . 4 5 s = 0 . 2 1 8

1

/

MEAN TOTAL LENGTH File: C:\ACTIONS\DDVMYSID2 Transform: NO TRANSFORM

t-test of Solvent and Blank Controls Ho:GRPl MEAN = GRP2 MEAN _ _ _ _ _ _ _ _ - _ - - _ - - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - GRPI (SOLVENT CRTL) MEAN = 6.6125 CALCULATED t VALUE = 0.3061 GRP2 (BLANK CRTL) MEAN = 6.5800 DEGREES OF FREEDOM = 6 DIFFERENCE IN MEANS - - 0.0325

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TABLE t VALUE (0.05 (2), 6) = 2.447 NO significant difference at alpha=0.05 TABLE t VALUE (0 .O1 ( 2 ) , 6) = 3.707 NO significant difference at alpha=0.01

\

MEAN TOTAL LENGTH File: c:\AcTIONS\DDVMYSID~ Transform: NO TRANSFORM

ANOVA TABLE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

' SOURCE DF SS MS F . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Between 5 2.113 0.423 22.263

Within (Error) 22 0.421 0.019 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

.Total 27 2.534 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Critical F value = 2.66 (0.05,5,22) Since F > Critical F REJECT Ho:A11 groups equal

MEAN TOTAL LENGTH File: C:\ACTIONS\DDVMYSID~ Transform: NO TRANSFORM ,

BONFERRONI T-TEST - TABLE 1 OF 2 Ho:Control<Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TRANSFORMED MEAN CALCULATED IN GROUP IDENTIFICATION MEAN ORIGINAL UNITS T STAT SIG - - - - - . . . . . . . . . . . . . . . . . . . . - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

1 GRPS 1&2 POOLED 6.596 6.596 2 0.746 6.482 6.482 1.348 3 1.48 6.510 6.510 ' 1.022 4 3.25 6.193 6.193 4.783 * 5 6.63 6.103 6.103 5.849 * 6 13.0 5.820 5.820 9.196 *

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Bonferroni T table value = 2.51 (1 Tailed Value, P=0.05, df=22,5)

MEAN TOTAL LENGTH File: C:\ACTIONS\DDVMYSID~ Transform: NO TRANSFORM

BONFERRONI T-TEST - TABLE 2 OF 2 Ho:Control<Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

,NUM OF Minimum Sig Diff % of DIFFERENCE GROUP IDENTIFICATION REPS (IN ORIG. UNITS) CONTROL FROM CONTROL --i__ . . . . . . . . . . . . . . . . . . . . - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 1 GRPS 1&2 POOLED 8 2 0.746 4 0.212 3.2 0.114 3 1.48 4 0.212 3.2 0.086 4 3.25 4 0.212 3.2 0.404 5 6.63 4 0.212 3.2 0.494 6 13.0 4 0.212 3.2 0.776

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

MEAN TOTAL LENGTH File: C:\ACTIONS\DDVMYSID~ Transform: NO TRANSFORM

ANOVA TABLE _ _ - _ _ _ _ _ _ - _ _ ~ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

SOURCE DF SS MS F _ _ _ _ _ _ _ - - - _ _ _ _ - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Between 5 2.113 0.423 22.263

Within (Error) 22 0.421 0.019 _ _ _ _ _ _ _ - _ - _ _ _ ~ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Total 27 2.534 _ _ _ _ _ _ _ _ _ _ _ _ _ _ - - _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Critical F value = 2.66 (0.05,5,22) Since F > Critical F REJECT Ho:A11 groups equal

- MEAN TOTAL LENGTH File: C:\ACTIONS\DDVMYSID2 Transform: NO TRANSFORM

TUKEY method of multiple comparisons - _ _ _ _ _ - - - - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

GROUP TRANSFORMED ORIGINAL 0 0 0 0 0 0

GROUP IDENTIFICATION MEAN MEAN 6 5 4 2 3 1 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

6 1

13.0 5.820 5.820 \ 5 6.63 6.103 6.103 . \ 4 3.25 6.193 '6.193 * . \ 2 0.746 6.482 6.482 * * . \ 3 1.48 6.510 6.510 * * * . \ 1 GRPS 1&2 POOLED 6.596 6.596 * * * . . \

_ _ _ _ _ - - - - - - _ - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - * = significant difference (p=0.05) . = no significant difference Tukeyvalue (6,22) = 4.45 s = 0.019

MEAN GROWTH OF MYSIDS File: C:\ACTIONS\DDVP\MYSID~ Transform: NO TRANSFORM

t-test of Solvent and Blank Controls Ho:GRPl MEAN = GRP2 MEAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

GRPl (SOLVENT CRTL) MEAN = 0.9500 CALCULATED t VALUE = 0.6085 GRP2 (BLANK CRTL) MEAN = 0.9150 DEGREES OF FREEDOM = 6 DIFFERENCE IN MEANS - - 0.0350

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TABLE t VALUE (0.05 (2), 6) = 2.447 NO significant difference at alpha=0.05 TABLE t VALUE (0.01 ( 2 ) , 6) = 3.707 NO significant difference at alpha=0.01

*

MEAN GROWTH OF MYSIDS File: c:\ACTIONS\DDVP\MYSID~ Transform: NO TRANSFORM

ANOVA TABLE _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

SOURCE DF SS MS F _ - - _ - - - _ - - _ _ _ _ _ _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Between 5 0.807 0.161 10.733

Within (Error) 22 0.321 0.015

Total 27 1.128

Critical F value = 2.66 (0.05,5,22) Since F > Critical F REJECT Ho:A11 groups equal

1 MEAN GROWTH OF MYSIDS 1 File: C:\ACTIONS\DDVP\MYSID~ Transform: NO TRANSFORM I

BONFERRONI T-TEST - TABLE 1 OF 2 Ho:Control<Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

- TRANSFORMED MEAN CALCULATED IN GROUP IDENTIFICATION MEAN ORIGINAL UNITS T STAT SIG - - - - - . . . . . . . . . . . . . . . . . . . . - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

1 GRPS 1&2 POOLED 0.932 0.932 2 0.746 0.850 0.850 1.100 3 1.48 0.910 0.910 0.300 4 3.25 0.720 0.720 ' 2.833 * 5 6.63 0.635 0.635 3.967 * 6 13.0 0.450 0.450 6.433 *

_ _ _ _ - _ _ _ _ - - - - - - _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

~onferroni T table value = 2.51 (1 Tailed Value, P=0.05, df=22,5)

MEAN GROWTH OF MYSIDS File: C:\ACTIONS\DDVP\MYSID3 Transform: NO TRANSFORM

BONFERRONI T-TEST - TABLE 2 OF 2 Ho:Control<Treatment _ _ _ _ - - - - - - - - d - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

NUM OF Minimum Sig Diff % of DIFFERENCE GROUP IDENTIFICATION REPS (IN ORIG. UNITS) CONTROL FROM CONTROL _ - - - - . . . . . . . . . . . . . . . . . . . . - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

1 GRPS 1&2 POOLED 8 2 0.746 4 0.188 20.2 0.082 3 1.48 4 0.188 20.2 0.023 4 3.25 4 0.188 20.2 0.212 5 6.63 4 0.188 20.2 0.297 - 6 13.0 4 0.188 20.2 0.483

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

MEAN GROWTH OF MYSIDS File: C:\ACTIONS\DDUP\MYSID~ Transform: NO TRANSFORM

- - - -----* *-___I -%-%--<--*(-I_--R-- "

ANOVA TABLE - - - - _ _ _ _ _ _ _ ~ _ _ _ _ _ - _ _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

SOURCE Dl? SS MS F _ - ~ _ _ ~ _ _ _ _ _ _ _ ~ _ _ _ _ - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Between 5 0.807 0.161 10.733

Within (Error) 22 0.321 0.015 - - - - - - _ _ _ ~ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ - - - - - - - - - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Total 27 1.128 - - - - - - - - - - _ _ _ _ _ _ - _ _ _ _ _ _ _ _ _ _ _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Critical F value = 2.66 (0.05,5,22) Si,nce F > Critical F REJECT Ho:A11 groups equal

MEAN GROWTH OF MYSIDS File: C:\ACTIONS\DDVP\MYSID3 Transform: NO TRANSFORM

TUKEY method of multiple comparisons _ _ ~ - _ _ - - - - _ _ - - - - - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

GROUP T ~ S F O R M E D ORIGINAL o o o o o o

GROUP IDENTIFICATION MEAN MEAN 6 5 4 2 3 1 _ - _ _ _ - - - - _ - _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 6 13.0 0.450 0.450 \ 5 6.63 0.635 0.635 . \ 4 3.25 0.720 0.720 . . \ 2 0.746 0.850 0.850 * . . \ 3 1.48 0.910 0.910 * * . . \ 1 GRPS 1&2 POOLED 0.932 0.932 * * . . . \ /

~ _ _ _ _ _ - - - _ _ _ - - - - - _ _ - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

* = significant difference (p=0.05) . = no significant difference Tukeyvalue (6,22) = 4.45 s = 0.015

DP BARCODE: D222024 REREG CASE # 0310

1 CASE: 819293 DATA PACKAGE RECORD DATE: 01/19/96

SUBMISSION: S498872 BEAN SHEET Page 1 of 1

I , * * * CASE/SUBMISSION INFORMATION * * * / CASE TYPE: REREGISTRATION ACTION: 606 GENERIC DATA I 1

/

CHEMICALS: 084001 Dichlorvos 100.00 % I r '

1 ID#: 084001

I COM~ANY : /

PRODUCT MANAGER: 61 RICHARD DUMAS 703-308-8015 ROOM: CS1 1H3 1 I PM TEAM REVIEWER: DENNIS UTTERBACK 703-308-8026 ROOM: CS1 2K5 I RECEIVED DATE: 11/22/95 DUE OUT DATE: 12/22/95 I <-a

-

1 * * * DATA PACKAGE INFORMATION * * * I DPBARCODE: 222024 EXPEDITE: N DATE SENT: 01/19/96 DATE RET.: / / I CHEMICAL: 084001 Dichlorvos 1 i DP TYPE: 001 Submission Related Data Package

CSF: N LABEL: N 1 ASSIGNED TO DATE IN DATE OUT ADMIN DUE DATE: 02/18/96

I DIV : EFED / 1 NEGOT DATE: / / BRAN: EEB / / PROJ DATE: -, / /

i SECT: I0 / / 1 1

1 REVR : / / CONTR : / / / /

1 ! * * * DATA REVIEW INSTRUCTIONS * * * I I

1 Please review mrid 438543-01 72-4(b) li?e cycle I invertebrates

1 * * * DATA PACKAGE EVALUATION * * * 1 I

I

No evaluation is written for this data package

I I * * * ADDITIONAL DATA PACKAGES FOR THIS SUBMISSION * * * I I DP BC BRANCH/SECTION DATE OUT DUE BACK INS CSF LABEL

i I I 1

I f

I I i I

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I '

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DP Barcode : D222024 PC Code No : 084001 EEB Out : / /

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To: Richard Dumas Product Manager 61 ,

Special Review and Reregistration Division (7508W)

From: Anthony F. Maciorowski, Chief Ecological Effects Erz~;h/ETE2 : 7507C)

-

Atkached, please find the EEB review of ... I Reg./File # : 0310

Chemical Name ': Dichlowos Type Product : insecticide 1 % Product Name :

I Company Name : Purpose : Review mysid life cycle study. ~

~ > Action Code: 606 Date Due: 2/18/96 Reviewer : ~ e ~ i n a ' Hirsch

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I EEB ~uideiine/MR~~ Summary Table: The review in this package contains an evaluation of the 1 , folJowing :

GDLN NO, 71-1 (A) 71 - 1 (B) 71-2 (A) 71-2 (B) 71-3 71 -4 (A) 71-4 (B) 71-5(A)

71-5 (B) 7'2 - 1 (A) 72-1 (B) 72 - 1 (C) 72-1 (D)

Y=Acceptable (Study satisfied Guideline) /Concur ' 8 j:

P=Partial (Study partially fulfilled Guideline but additional information is needed ,

S=Supplemental (Study provided useful information but Guideline was 3 not satisfied) /

N=Unacceptable (Study was rejected) /Nonconcur \

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MRID NO

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.

CAT

,

GDLN NO 72 - 2 (A) 72-2 (B) 72 - 3 (A) 72-3 (B) 72'-3 (C) 72-3 (D) 72-3 (E) 72-3 (I?) 72 - 4 (A) 72-4 (B) '

72-5 72-6

MRID NO

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' $365 Ce) -o(

CAT

L.

GDLNNO 72-7 (A) 72-7 (B) 122-1 (A) 122-1 (B) 122-2 ' 123 -1 (A) 123 - 1 (B) 123-2 124-1 124-2 141-1 141-2 I

141-5

MRIDNO

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CAT I


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