Vibrio vulnificus Biotype 3 Multifunctional Autoprocessing RTX Toxin

Is an Adenylate Cyclase Toxin Essential for Virulence in Mice

Kevin J. Ziolo, Hee-Gon Jeong, Jayme S. Kwak, Shuangni Yang, Robert M. Lavker, Karla J. F. Satchell

Infection and Immunity 2014 May vol. 82 (5) p2148-212157

RTX b-barrel pore-forming toxin.

Schematic illustration of the molecular structure of the interaction between leukotoxin of Aggregatibacter actinomycetemcomitans and the target cell membrane.

Synthesis of RTX toxins.

IP6, inositolhexakisphosphate.

Clostridium difficile toxins A and B, glucosylation of Rho.

Vibrio cholerae MARTX.

Ziolo Kevin et al. (2014) Infect. Immun. Fig.1

Ziolo Kevin et al. (2014) Infect. Immun. Fig.2

Ziolo Kevin et al. (2014) Infect. Immun. Fig.3ab

Ziolo Kevin et al. (2014) Infect. Immun. Fig.3c

Ziol

o Ke

vin

et a

l. (2

014)

Infe

ct. I

mm

un. F

ig.4

b

Ziolo Kevin et al. (2014) Infect. Immun. Fig.4a

Ziolo Kevin et al. (2014) Infect. Immun. Fig.5a

Ziolo Kevin et al. (2014) Infect. Immun. Fig. 5b

Ziolo Kevin et al. (2014) Infect. Immun. Fig.5c

Ziol

o Ke

vin

et a

l. (2

014)

Infe

ct. I

mm

un. F

ig.6

ab

Ziolo Kevin et al. (2014) Infect. Immun. Fig.6c

Ziol

o Ke

vin

et a

l. (2

014)

Infe

ct. I

mm

un. F

ig.7