Updated 4.24.15 CURRICULUM VITAE James Russell Sowers, MD, ASCI, FACP, FAHA Office Address(s) Department of Internal Medicine Division of Endocrinology D109 Diabetes Center - UHC One Hospital Drive Columbia, MO 65212 Harry S Truman Memorial Veterans Hospital (Truman VA) Research Service 800 Hospital Drive Columbia MO 65201 MU Office Office Telephone: Cell Telephone: Fax: Email: (573) 884-0769 (573) 823-1002 (573) 884-5530 [email protected]EDUCATION 1965 1965-1966 1971 Bachelor of Science in Chemistry - Missouri State and University of Missouri, Columbia, Missouri University of Missouri Graduate School in Physiology/ Biochemistry MD - University of Missouri Medical School, Columbia, Missouri TRAINING 1971-1974 1974-1976 Internal Medicine Residency, University of Alabama Hospitals and Clinics and St. John's Mercy Medical Center, St. Louis, Missouri Fellowship in Endocrinology, Department of Medicine, California,
Transcript
Updated 4.24.15
CURRICULUM VITAE
James Russell Sowers, MD, ASCI, FACP, FAHA
Office Address(s) Department of Internal MedicineDivision of Endocrinology
D109 Diabetes Center - UHCOne Hospital Drive
Columbia, MO 65212
Harry S Truman Memorial Veterans Hospital (Truman VA) Research Service
07/1979-07/1983 Associate Professor of Medicine UCLA07/1979-07/1983 Chief, Neuroendocrine Labs, UCLA, San Fernando
Valley Program07/1983-12/1984 Chief of Endocrinology and Hypertension, McGuire
Veterans Administration Medical Center, Richmond, Virginia
07/1983-12/1984 Associate Professor of Medicine, Medical College of Virginia
12/1984-11/1999 Director, Division of Endocrinology, Metabolism andHypertension, Wayne State University, Detroit, Michigan
12/1984-11/1999 Professor of Medicine and Physiology, Wayne State University
School of Medicine12/1984-11/1999 Staff Physician, Medical Service VAMC, 4646 John R,
Detroit, MI11/1999-10/2003 Chief, Endocrinology, Diabetes and Hypertension,
SUNY HSC at Brooklyn, New York11/1999-10/2003 Staff Physician, Medical Service VAMC, Brooklyn, New
York10/2003-10/2006 Associate Dean of Clinical Research, School of
Medicine, University of Missouri-Columbia, Columbia, Missouri
10/2003-10/2006 Vice Chair of Research, Dept of Internal Medicine, University of
Missouri-Columbia, Columbia, Missouri10/2003-10/2006 Director, Diabetes and Cardiovascular Disease Center,
Columbia, Missouri
10/2003-10/2006 Professor of Medicine, Physiology & Pharmacology, University of Missouri-Columbia, Columbia, Missouri
10/2003-10/2006 Staff Physician, Medical Service, Truman VA, Columbia, Missouri
10/2006-03/2007 Professor of Medicine and Physiology, Director of Diabetes, Hypertension and Metabolism Research, University of Arizona, Tucson, Arizona
04/2007-Present Thomas W. and Joan F. Burns Missouri Chair in Diabetology
04/2007-Present Director, Center for Diabetes and Cardiovascular Research, Columbia, Missouri
04/2007-Present Director, Division of Endocrinology, Diabetes & Metabolism, University of Missouri-Columbia, Columbia, Missouri
04/2007-Present Staff Physician, Medical Service, Truman VA, Columbia, Missouri
04/2007-Present Professor of Medicine, Physiology & Pharmacology, University of Missouri-Columbia, Missouri
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04/2007-04/2015 Vice-Chair for Research, Department of Internal Medicine, University of Missouri-Columbia, Columbia, Missouri
MAJOR PROFESSIONAL SOCIETIESAmerican Society Clinical InvestigationAlpha Omega Alpha, Honor Medical SocietyAmerican Physiology SocietySociety of Vascular MedicineAmerican Federation of Clinical ResearchFellow, High Blood Pressure CouncilAmerican College of PhysiciansEndocrine SocietyAmerican Diabetes AssociationAmerican Society of HypertensionAmerican College of Physicians (Fellow)Southern, Western, and Central Society of Clinical InvestigationInternational Society of HypertensionInternational Society of Hypertension in BlacksInter-American Society of Hypertension
LICENSURE & BOARD CERTIFICATION(S)19741977
Boards in Internal Medicine Boards in Endocrinology State Licenses – Arizona, California, Michigan, Missouri, Virginia, New York
Irvine Page-Alva Bradley Lifetime Achievement Award in HypertensionCOSEHC Lifetime Achievement AwardSeale Harris Research Award, Southern Medical AssociationFellow in the American Society of HypertensionUniversity of Missouri, Medical Alumni Organization Citation of MeritAlpha Omega Alpha Honor Medical Society InducteeMidwestern Outstanding Research award of AHADetroit Federal Executive Board-Distinguished ScientistDistinguished Teacher of Department of Medicine, Wayne State UniversityLange Medical Award for Scholastic and Research Achievement
SERVICEProfessional Consultation (other patient care) Public presentations as an expert in endocrinology, metabolism and
hypertension and vascular medicine
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No consulting to public agencies, foundations, or professional associations
Journal of HypertensionJournal of American Society of HypertensionCardiovascular Drug ReviewsAmerican Journal Clinical HypertensionAmerican Journal HypertensionEndocrinology, Nutrition, Metabolism and Cardiovascular Diseases, Journal of Clinical Endocrinology & Metabolism
1994-Present1991-Present1991-Present
Journal of Human HypertensionMetabolismHypertension
Editorships - ReviewerNew England Journal of MedicineHypertensionJournal of Biological ChemistryCirculationCirculation ResearchAmerican Journal of PhysiologyDiabetesJournal of Clinical InvestigationJournal of Clinical Endocrinology and MetabolismEndocrinology American Journal of MedicineArchives of Internal MedicineAnnals Internal MedicineJournal American Medical Association
Other Professionally Related Service NIH, VA Merit Board, American Heart National Reviews
Committees Department of Veterans Affairs (VA) Joint Biomedical Laboratory
Researchand Development and Clinical Science Research and Development Scientific Merit Review Board
VCMB (Vascular Cell Molecular Biology) Study Section - NIH Data Monitoring Committee “Combination Angiotensin Receptor
Blocker and Angiotensin converting Enzyme Inhibitor for
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Treatment of Diabetic Nephropathy. Cooperative Studies Program Coordinating Center. VA Connecticut Healthcare System
Microcirculation Study Section – NIH
National and International Boards and Committees National Kidney Foundation Hypertension and Diabetes Executive
Committees Working Group Hypertension in African Americans Working Group of the International
Society on Hypertension in Blacks. Educational Committee - High Blood Pressure Council Scientific Awards Committee - American Society of Hypertension External Advisory Board – COBRE grant “Hypertension and
Cardiorenal Disease Research Center, John Hall, University of Mississippi
State and Local Boards and Committees 2011-Present2004-Present2004-Present2004-Present2001-2004
University of Missouri Internal Medicine Research Council, Chair SOM Administrators Research Council (ARC) Vice Chair, Truman VA Research and Development (R&D) Committee Research and Development (R&D) Committee; ACCORD Truman VA Brooklyn VA Research and Development (R&D) Committee, Chair
COMMITTEES AND STUDY SECTIONS 2010-20151989-1993 &2008-Present2007-20102004-20091990-1994 &2006-Present2004-20072004-20062004-2006
Charter Member VCMB Study Section – NIHAmerican Heart Association - Cardiovascular and Renal Study Section
AHA Council for High Blood PressureScientific Oversight Committee – NIH-ACCORD TrialVA Merit Review Board – Endocrinology
Subcommittee for Animal Studies (SAS), Truman VA HospitalAdmissions Committee, University of Missouri School of MedicineChairman, Promotion and Tenure Committee, University of Missouri School of MedicineNIH Cardiovascular Sections, Ad Hoc Reviewer
American Society of Hypertension Executive Council
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1996-200119981985-19971990-19931993
1989-1992
1990-19911989-19911989-1990
NIH GCRC Site Visits
Brooklyn Manhattan VA, R & D, ChairNIH Experimental Cardiovascular Sciences Study Section MemberISHIB International Conference, Co-ChairUS-Israel Bi-national Science Foundation - Grant ReviewerCardiovascular Regulation Research Study Committee, AHANIH Consensus on Hypertension and Diabetes NIH Joint National Committee for Blood Pressure (JNC 6 and 7), ChairmanNDC-Nutrition Research Science Advisory Committee Member/ReviewerPromotion and Tenure Committee, WSU School of Medicine, ChairmanWayne State University Executive CommitteeConsultant NIH Study Section for (SCOR) Hypertension Grants
TEACHING
Years at Universities1979-19831983-19851985-19991999-20031976-1979 &2003-Present
UCLA School of Medicine, Los Angles, CaliforniaMedical College of Virginia, Richmond, VirginiaWayne State University, Detroit, MichiganSUNY Downstate- Brooklyn, New YorkUniversity of Missouri, Columbia, Missouri
Paul Standley, Ph.D. Thesis: “Insulin and Hypertension”Feng Zhang, Ph.D. Thesis: “Sex Hormones and Vascular Calcium Currents”Ranganath Muniyappa Ph.D. Thesis: “Signal Transduction Mechanisms Mediating IGF-1 Induced Nitric Oxide Release in Endothelial Cells”
Clinical Teaching Activities Attending Faculty – VA Clinic – 3 clinics per week Attending Weekend Consult Faculty – 3 months per year Attending Fellow Clinic – UMC – 6 weeks per year
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GRANT SUPPORT2012-2017 Principal Investigator: James Sowers, MD $650,000
Biomedical Laboratory Research and Development (BLR&D) Merit Review“Interactions of the RAAS and a Western Diet on Insulin Metabolic Actions”
2011-2016 Principal Investigator: James Sowers, MD $1,250,000NHLBI, NIH“Ang II and Overnutrition and Insulin Resistance in Cardiovascular Tissue”
2009-2014 Principal Investigator: James Sowers, MD $1,250,000NHLBI, NIH“Ang II and Aldosterone Effects on Insulin Resistance in Cardiovascular Tissue”
2008-2012 Principal Investigator: James Sowers, MD $650,000Biomedical Laboratory Research and Development (BLR&D) Merit Review“Mechanisms of Angiotensin II and Aldosterone Inhibition of Insulin Metabolic Signaling”
2006-2009 Principal Investigator: Jamal Ibdah, MDCo-Principal Investigator: James Sowers, MD
$200,000
Department of Health & Human Services“Beta-Oxidation and Susceptibility to Fatty Liver Disease”
2005-2010 Principal Investigator: Virginia Huxley, PhD $292,000Co-Principal Investigator: James Sowers, MDNHLBI, NIH“Molecular, Cellular and Systems Biomedicine”
2005-2008 Principal Investigator: Habib Zaghouani, PhD
$175,000
Co-Principal Investigator: James Sowers, MDNIDDK, NIH“Immune Tolerance Against Type I Diabetes in Mice”
2004-2009 Principal Investigator: James Sowers, MD $135,000Biomedical Laboratory Research and Development (BLR&D) Merit Review“Vascular Protein Kinase B/Akt and Rho Signaling: Interactions of
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IGF-1 and Ang II”
2004-2009 Principal Investigator: Mark Milanick, PhD $162,579Co-Principal Investigator: James Sowers, MDNIDDK, NIH“From Clinic to Bench and Back: Clinical Biodetective Training”
2004-2008 Principal Investigator: James Sowers, MD $200,000.NHLBI“Ang II Opposes INS Mediated Vasorelaxation and GLU Utilization”
2004-2008 Principal Investigator: Meredith Hay, PhD $34,000Co-Principal Investigator: James Sowers, MDNHLBI, NIH, University of Iowa“Circumventricular Organs: Gender and Hypertension”
2004-2006 Principal Investigator: Virginia Huxley, PhD $266,599Co-Principal Investigator: James Sowers, MDNHLBI, NIH“Cardiovascular and Renal Physiology, Pharmacology and Biochemistry”
2000-2003 Principal Investigator: James Sowers, MD $299,997ADA“Vascular Interactions of Estradiol and Insulin-Like Growth Factor: Impact of Insulin Resistance and Hypertension”
1990-2004 Principal Investigator: James Sowers, MD $982,361NIH“Ang II and IGF-1 Interaction in Cardiovascular Tissue”
1999-2002 Principal Investigator: James Sowers, MD $450,000Biomedical Laboratory Research and Development (BLR&D) Merit Review“Vascular Action of Insulin and IGF-1: PI3-Kinase Related Resistance”
1994-1999 Principal Investigator: James Sowers, MD $569,800Biomedical Laboratory Research and Development (BLR&D) Merit Review“Actions of Insulin and IGF-I on Vascular Smooth Muscle Cation and
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Glucose Metabolism”
1994-1999 Principal Investigator: James Sowers, MD $159,000National Heart, Lung, and Blood Institute & DVA“Department of Veteran's Affairs Vanguard Site in the Antihypertensive and Lipid-Lowering Therapy to Prevent Heart Attack Trial (ALLHAT)”
1990-1994 Principal Investigator: James Sowers, MD $320,000.Biomedical Laboratory Research and Development (BLR&D) Merit Review“Insulin Resistance and Hypertension”
1990-1993 Principal Investigator: John Waller, MD $1,460,457Co-Principal Investigator: James Sowers, MDNIH“Health Promotion and Disease Prevention”
1987-1996 Principal Investigator: James Sowers, MDNIH“Insulin Resistance & Altered Cellular Calcium Metabolism in Pregnancy”
7. Sowers JR, Hershman JR, Skowsky WR. Effect of TRH on serum arginine vasopressin in euthyroid and hypothyroid subjects. Hormone Res. 1976;7:232-237.
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8. Sowers JR, Carlson HE, Brautbar N, Hershman JM. Effect of dexamethasone on prolactin and TSH responses to TRH and metoclopramide in man. J Clin Endocrinol Metab. 1977;44(2):237-241.
9. Sowers JR, Hershman JM, Skowsky WR, Carlson HE, Park J. Osmotic control of the release of prolactin and thyrotropin in euthyroid subjects and patients with pituitary tumors. Metabolism. 1977;26(2):187-192.
10. Carlson HE, Sowers JR, Rand RW. Lack of effect of thyroid hormones on the growth hormone response to thyrothropin-releasing hormone in acromegaly. Metabolism. 1977;26(7):801-805.
11. Sowers JR, Raj RP, Hershman JM, Carlson HE, McCallum RW. The effect of stressful diagnostic studies and surgery on anterior pituitary hormone release in man. Acta Endocrinol (KEH). 1977;86(1)25-32.
12. Levine GA, Sowers JR, Hershman JM. The use of intramuscularly administered methyl-TRH to evaluate the pituitary-thyroid axis. Horm Metab Res. 1978;10:(3)233-236.
13. Rubin RT, Poland RE, Sowers JR, Hershman JM. Influence of methyl-TRH induced prolactin increase on serum testosterone levels in normal adult men. J Clin Endocrinol Metab. 1978;46:830-833.
14. Sowers JR, Fayez J, Colantino M, Jonas H. The effect of intra-amniotic prostaglandin F2-alpha on anterior pituitary hormone release during midtrimester abortion. Fertility and Sterility. 1978;30:403-407.
15. Sowers JR, Hershman JM, Carlson HE, Pekary AE. Effect of HCG on thyroid function in euthyroid men. J Clin Endocrinol Metab. 1978;47:898-901.
16. Sowers JR, Colantio M, Fayez J, Jonas H. Pituitary response to LHRH in midtrimester pregnancy. Obstet Gynecol. 1978;52:685-688.
17. Sowers JR, Tempel G, Resch G, Colantio M. Pituitary response to TRH and LHRH in spontaneously hypertensive rats. Proc Soc Exp Biol Med. 1978;159:397-399.
18. Sowers JR, Resch G, Tempel G, Herzog J, Colantio M. Hyperprolactinemia in the spontaneously hypertensive rat. Acta Endocrinol. 1979;90:1-7.
19. Sowers JR, Pekary E, Hershman JM, Kanter M, DiStefano III JJ. Metabolism of exogenous human chorionic gonadotropin in men. J Endocrinol. 1979;80:83-89.
20. McCallum RW, Sowers JR, Carlson HE. Effect of endogenous hyperprolactinemia on lower esophageal sphincter pressure: Its significance in relation to heartburn in pregnancy. Am J Gastroenterol. 1979;71:259-263.
21. Levy CL, Carlson HE, Sowers JR, Goodlett RE, Tourtellotte WW, Hershman JM. Growth hormone and prolactin secretion in Huntington's disease. Life Sci. 1979;24:743-749.
22. Sowers JR, Fayez J. Effect of dexamethasone on gonadotropin responsiveness to luteinizing hormone-releasing hormone and clomiphene in women with secondary amenorrhea. Amer J Obstet Gynecol. 1979;134:325-328.
23. Sowers JR, Rice BF, Blanchard S. Effect of dexamethasone on luteinizing hormone and follicle stimulating hormone responses to LHRH and to clomiphene in the follicular phase of women with normal menstrual cycles. Horm Metab Res. 1979;11(8): 478-480.
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24. Sowers JR, Sollars E, Herzog J, Rice B. The effect of neoplasia-induced hypercalcemia on the neuroendocrine axis of the fischer rat. Metabolism. 1980;29(2):146-150.
25. Sowers JR, Walker S, Herzog J. Inhibition of anterior pituitary hormone release by infusion of calcium chloride in the rat. Endocrinology. 1980;106(6):1809-1814.
26. Fayez J, Sowers JR. Evaluation and treatment of patients with prolactin-secreting pituitary tumors. International J Obstet Gynecol. 1980;17:421-427.
27. Sowers JR, Resch G, Walker S, Sollars E. Developmental patterns of the hypothalamic-pituitary axis in the euthyroid and hypothyroid male rat. Neuroendocrinol. 1980;30:257-261.
28. Sowers JR, Barrett JD, Sambhi MP. Effect of L-dopa and bilateral nephrectomy on the aldosterone response to metoclopramide. Life Sci. 1980;27(6):497-501.
29. Sowers JR, Tuck M, Asp N. Dopaminergic modulation of renin activity and aldosterone and prolactin secretion in the spontaneously hypertensive rat. Proc Soc Exp Biol Med. 1980;164(4):598-603.
30. Sowers JR, Tuck ML, Golub MS, Sollars E. Dopaminergic modulation aldosterone secretion is independent of alterations in renin secretion. Endocrinology. 1980;107:937-941.
31. Sowers JR, Sollars E. Effect of rendering male rats hypothyroid at different stages of development adenohypophysial hormone release. Horm Metab Res. 1980;12:524-528.
32. Whitfield L, Sowers JR, Tuck M, Golub MS. Dopaminergic control of plasma catecholamine and aldosterone responses to acute stimuli in normal man. J Clin Endocrinol Metab. 1980;51(4):724-729.
33. Sowers JR, Tuck M, Barrett JD, Sambhi MP, Golub M. Dopaminergic control of aldosterone secretion is independent of the renin-angiotensin system in rats. Clinical Science. 1980;59(6)101S-103S.
34. Sowers JR, Tuck M, Sowers D. Plasma antithrombin III and thrombin generation time: Correlation with hemoglobin Alc and fasting serum glucose in young diabetic women. Diabetes Care. 1980;3:655-658.
35. Stene M, Panagiotis N, Tuck M, Sowers JR. Plasma norepinephrine levels are influenced by sodium intake, glucocorticoid administration and circadian changes in normal man. J Clin Endocrinol Metab. 1980;51:1340-1345.
36. Sowers JR, Golub M, Tuck M, Sowers DK. Role of prolactin and the renin-angiotensin system in mediating dopaminergic control of aldosterone secretion in the rat. Clin Exp Hyper. 1981;3(1)1-14.
38. Sowers JR, Tuck M, Asp N, Sollars E. Plasma aldosterone and corticosterone responses to ACTH, angiotensin, potassium and stress in spontaneously hypertensive rats. Endocrinology. 1981;108:1216-1221.
39. Sowers JR, Brickman A, Asp ND, Tuck ML, Jasberg K. Altered dopaminergic modulation of prolactin and aldosterone secretion in pseudohypo-parathyroidism. J Clin Endocrinol Metab. 1981;52:914-918.
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40. Tuck ML, Sowers JR, Dornfeld L, Kledzik G, Maxwell M. The effect of weight reduction on blood plasma renin activity and plasma aldosterone levels in obese patients. New England J Med. 1981;304:930-933.
41. Sowers JR, Sharp B, Levin ER, Golub MS, Eggena P. Metoclopramide, a dopamine antagonist, stimulates aldosterone secretion in rhesus monkeys but not in dogs or rabbits. Life Sci. 1981;29(21):2171-75.
42. Tuck ML, Sowers JR, Fittingoff DB, Mayes DM. Plasma corticosteroid concentrations during spironolactone administration: evidence for adrenal biosynthetic blockade in man. J Clin Endocrinol Metab. 1981;52(6):1057-1061.
43. Sowers JR, Brickman AS, Sowers DK, Berg G. Dopaminergic modulation of aldosterone secretion in man is unaffected by glucocorticoids and angiotensin blockage. J Clin Endocrinol Metab. 1981;52:1078-1084.
44. Sowers JR. Effects of bromocriptine on responses to stress in spontaneously hypertensive rats. Hypertension. 1981;3:544-550.
45. Sowers JR, Sollars E, Nyby M, Jasberg K, Tuck ML. Hypereninimic hypoaldosteronism in association with neoplasis induced hypercalcemia in the fischer rat. Metabolism. 1981;30(10):987-991.
46. Stricker SJ, Sowers DK, Sowers JR, Sirridge M. "Effort Thrombosis" of the subclavian vein associated with oral contraceptives. Annals Emerg Med. 1981;10(11):596-599.
47. Sowers, JR. Dopaminergic control of circadian norepinephrine levels in patients with essential hypertension. J Clin Endocrinol Metab. 1981;53(6):1133-1137.
48. Sowers JR, Golub MS, Eggena PH, Catania RA. Influence of sodium homeostasis on dopaminergic modulation of aldosterone, renin and prolactin secretion in man. J Clin Endocrinol Metab. 1982;54:121-126.
49. Sowers JR, Catania R, Paris J, Tuck M. Effects of bromocriptine on renin, aldosterone, and prolactin responses to posture and metoclopramide in idiopathic edema: Possible therapeutic approach. J Clin Endocrinol Metab. 1982;54:510-516.
51. Sowers JR, Catania RA, Hershman JM. Evidence for dopaminergic control of circadian variations in thyrotropin secretion. J Clin Endocrinol Metab. 1982;54:673-675.
52. Sowers JR, Berg G, Martin VS, Mayes DM. Dopaminergic modulation of aldosterone secretion in the rhesus monkey: evidence that dopamine affects the late pathway of aldosterone biosynthesis by inhibiting the conversion of corticosterone to 18-hydroxycorticosterone. Endocrinology. 1982;110:1173-1177.
53. Sowers JR, Sharp B, McCallum RW. Effect of domperidone, and extracerebral inhibitor of dopamine receptors on thyrotropin, prolactin, renin, aldosterone and 18-hydroxycorticosterone secretion in man. J Clin Endocrinol Metab. 1982;54:869-871.
54. Berger ML, Golub ME, Sowers JR, Brickman AS, Nyby M, Troyer H, Rude RK, Singer FR, Horst R, Deftos LJ. Hypercalcemia in association with a Leydig cell
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tumor in the rat: a model for tumor-induced hypercalcemia in man. Life Sci. 1982;30:1509-1515.
55. Sowers JR, Stern N, Tuck ML, Dornfeld L, Maxwell M. Role of the sympathetic nervous system in blood pressure maintenance in obesity. J Clin Endocrinol Metab. 1982; 54(6):1181-1186.
56. Sowers JR, Barrett JD. Hormonal changes associated with hypertension in neoplasia-induced hypercalcemia. Am J Physiol. 1982;242(5):E330-E334.
57. Sowers JR, Martin VI, Stern N, Berg G. Dopaminergic control of 18-hydroxycorticosterone responses to posture, isometric exercise and diuretic administration in normal man. J Clin Endocrinol Metab. 1982; 55:475-480.
58. Troyer H, Sowers JR, Babich E. Leydig cell tumor-induced hypercalcemia in the fischer rat: morphometric and histochemical evidence for a humoral factor which activates osteoclasts. Amer J Pathol. 1982;108:284-290.
59. Sowers JR, Golub M, Berger M, Whitfield LA. Dopaminergic modulation of pressor and hormonal responses in essential hypertension. Hypertension. 1982;4:424-430.
60. Sowers JR, Nyby M, Stern N, Beck F, Baron S, Catania R, Vlachis N. Blood pressure and hormone changes associated with weight reduction in the obese. Hypertension. 1982;4:686-691.
61. Sowers JR, Nyby M, Jasberg K. Dopaminergic control of prolactin and blood pressure: altered control in essential hypertension. Hypertension. 1982; 4:431-438.
62. Golub MS, Sowers JR, Eggena P, Baron SH. Effect of prostaglandin inhibition on prolactin, renin and aldosterone responses to dopamine antagonism. Metabolism. 1982;31:740-743.
63. Sowers JR, Stern N, Nyby MD, Jasberg KA. Dopaminergic regulation of circadian rhythms of blood pressure, renin and aldosterone in essential hypertension. Cardiovasc Res. 1982;16:317-323.
64. Barrett J, Eggena P, Sowers JR, Sambhi MP. Effects of stimulation of renin release on trypsin-activatable renin in rat plasma. Amer J Physiol. 1982;243:E206-E212.
65. Sowers JR, Eggena P, Phillips D. Effect of metoclopramide and domperidone on aldosterone, 18-hydroxycorticosterone and prolactin secretion in the rhesus monkey. Metabolism. 1982;31:1219-1223.
66. Sowers JR, Beck F, Berg G. Altered dopaminergic modulation of 18-hydroxycorticosterone secretion in idiopathic edema: therapeutic effects of bromocriptine. J Clin Endocrinol Metab. 1982;55:749-756.
68. Sowers JR, Stern N. Influence of sodium homeostasis and circadian rhythm on dopaminergic modulation of 18-hydroxycorticosterone secretion in man. J Clin Endocrinol Metab. 1982;5:1046-1051.
69. Sowers JR, Stern N, Taylor IL. Evidence for dopaminergic modulation of pancreatic polypeptide secretion in man. Life Sci. 1982;31:2971-2975.
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70. Sowers JR. Modulation of corticosteroid secretion by dopaminergic mechanisms in rhesus monkeys. Amer. J Physiol. 1982;243:(5)E375-379.
71. Sowers JR, Whitfield LA, Beck FWJ, Catania RA, Tuck ML, Dornfeld L, Maxwell M. Role of enhanced sympathetic nervous system activity and reduced Na+, K+-dependent adenosine triphosphatase activity in maintenance of elevated blood pressure in obesity: effects of weight loss. Clin Sci. 1982;63:121-124.
72. Troyer H, Sowers JR, Barich E. Degenerative changes in the digestive glands of rats bearing Leydig cell tumors. Virchows Arch (Cell Pathol). 1982;40(3):395-403.
73. McGinty D, Littner M, Young E, Sowers JR. Sleep related breathing disorders in older men: A search for underlying mechanisms. Neurobiology of Aging. 1982;3:337-350.
74. Stern N, Beck F, Sowers JR. Effect of aldosterone on human erythrocyte sodium-potassium pump in vitro. Clin Sci. 1983;64:183-186.
75. Sharp B, Sowers JR. Adrenocortical response to corticotropin is inhibited by 3-MSH antisera in normotensive and spontaneously hypertensive rats. Biochem Biophysic Res Commun. 1983;110:357-363.
76. Sowers JR, Beck F. Dopaminergic regulation of 18-hydroxycorticosterone and aldosterone secretion in man. Acta Endocrinol. 1983;102:258-264.
77. Tuck ML, Sowers JR, Dornfeld L, Whitfield L, Maxwell M. Reductions in plasma catecholamines and blood pressure during weight loss in obese subjects. Acta Endocrinol. 1983;102(2):252-257.
78. Sowers JR, Martin V, Beck F. Effects of dietary sodium on circadian rhythm and physiological response of 18-hydroxycorticosterone. Clin Sci. 1983;64:295-301.
79. Sowers JR, Barrett JD. The renin-angiotensin system in association with hyperreninaemic hypoaldosteronism in neoplasia induced hypercalcemia. Acta Endocrinol. 1983;102:1-8.
80. Stern N, Sowers JR, Taylor IL, Golub M. Dopaminergic modulation of meal-stimulated and circadian secretion of pancreatic polypeptide in man. J Clin Endocrinol Metab. 1983;56(2)300-304.
81. Sowers JR, Beck F, Stern F, Raghavan SRV. Reduced sodium potassium dependent-ATPase and its possible role in the development of hypertension in spontaneously hypertensive rats. Clin Exper Hypertension. 1983;A5(1):71-86.
82. Krishna G, Danovitch GM, Sowers JR. Catecholamine responses to central volume expansion produced by head-out-water immersion and saline infusion. J Clin Endocrinol Metab. 1983;56(5):998-1002.
83. Sowers JR, Viosca S, Windsor C, Korenman S. Influence of dopaminergic mechanism on 24-hour secretory patterns of PRL, LH and testosterone in recumbent men. J Endo Invest. 1983;6:9-15.
84. Sowers JR. Dopaminergic control of prolactin and blood pressure. Hypertension. 1983;5(1):155-157.
85. Baron SH, Sowers JR, Fineberg M. Prolactinoma in a man following industrial exposure to estrogens. West J Med. 1983;138:720-722.
86. Sowers JR, Rubenstein LZ, Stern N. Plasma norepinephrine responses to posture and isometric exercise increase with age in the absence of obesity. J Gerontol. 1983;38(3):315-317.
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87. Sowers JR, Fittinghoff M, Tuck ML, Krall J. Acute changes in noradrenaline levels do not alter lymphocyte-adrenergic receptor concentrations in man. Cardiovasc Res. 1983;17(3):184-188.
88. Sowers JR, Beck FWJ. Dopaminergic modulation of corticosteroid response to angiotensin II in man. Clin Exper Hyper. 1983;A5(5):651-664.
89. Stern N, Beck F, Sowers JR, Tuck M, Hsueh WA, Zipser RD. Plasma corticosteroids in hyperrenineamic or hypoaldosteronism: Evidence for diffuse impairment of the zona glomerulosa. J Clin Endocrinol Metab. 1983;57:217-220.
90. Sowers JR, Beck F, Stern N, Asp N. Effects of metoclopramide on plasma corticosteroid levels in sheep. Endocrinology. 1983;113:903-906.
91. Golub MS, Eggena P, Sowers JR. Hypertension symposium: Newer topics on normal and abnormal regulatory mechanisms. West J Med. 1983;139:190-203.
92. Sowers JR, Tuck ML, Beck FWJ, Stern N. Effects of bromocriptine on the circadian rhythm of 18-hydroxycorticosterone and cortisol secretion in essential hypertensives. J Hypertension. 1983;1:141-144.
93. Sowers JR, Beck FWJ, Stern N. Glucocorticoid suppression enhances the 18-hydroxycorticosterone and aldosterone response to metoclopramide in man. Life Sci. 1983;33(25):2489-2495.
94. Stern N, Beck FWJ, Eggena P, Phillips D, Sowers JR. Corticosteroid modulation of the renin system and blood pressure in the spontaneously hypertensive rat. Clin Exper Hyper. 1983;A5(9):1543-1557.
95. Stern N, Beck FWJ, Sowers JR. Altered corticosteroid control of the erythrocyte sodium-potassium pump in the spontaneously hypertensive rat. J Hypertension. 1983;1:339-343.
96. Stern N, Beck FWJ, Vlachakis N, Eggena P, Sowers JR. Sodium-potassium ATPase in deoxycorticosterone-salt hypertension: Opposing effects of sodium load and mineralocorticoids. Endocrinology. 1984;114(2):624-628.
97. Stern N, Beck FWJ, Sowers JR. The role of corticosteroids in the regulation of myocardial Na, K-ATPase in normotensive and spontaneously hypertensive rats. Clin Sci. 1984;(66):421-426.
98. Sowers JR, Beck FWJ, Eggena P. Evidence for direct inhibitory effects of dopamine on zona glomerulosa secretion of 18-hydroxycorticosterone in rhesus monkeys. Life Sci. 1984;34:2339-2346.
99. Sowers JR, Beck FWJ, Eggena P. Effect of ganglionic blockade with trimethaphan on corticosteroid responses to metoclopramide in rhesus monkeys. J Hyperten. 1984;2:367-370.
100. Sowers JR. The impact of diuretics on potassium and glucose. J Cardiovasc Pharmacol. 1984;6:S477- S482.
101. Stern N, Lee DBN, Deftos L, Manolagas SC, Sowers JR. Effects of high calcium intake on blood pressure and calcium metabolism in young SHR. Hypertension. 1984;6(5)639-646.
102. Sowers JR, Crane PD, Beck FWJ, McClanahan M, Mohanty PK. Relationship between urinary dopamine production and natriuresis after acute intravascular volume expansion with sodium chloride in dogs. Endocrinology. 1984;115(6)2085-2090.
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103. Littner M, Young E, McGinty D, Sowers JR. Awake abnormalities of control of breathing and of the upper airway: Occurrence in healthy older men with nocturnal disordered breathing. Chest. 1984;86:573-579.
104. Sowers JR, Vlachakis N. Circadian variation in plasma dopamine levels in man. J Endocrinol Investigations. 1984;7:341-345.
105. Catania RA, Sowers JR, Stern N, Tuck ML, Paris J. Altered dopaminergic modulation of sympathetic nervous system activity in idiopathic edema. J Endocrinol Investigations. 1984;7:461-466.
106. Sowers JR, Beck FWJ. Role of dopamine in the regulation of aldosterone and 18-hydroxycorticosterone secretion in man. J Endocrinol Investigations. 1984;7:473-479.
107. Stern N, Sowers JR, Tuck M, Eshkol A, Lunenfieldl B, Rosenthal T. Enhanced response of plasma aldosterone to metoclopramide in essential hypertension. J Hypertension. 1984;2:209-214.
108. Tuck ML, Stern N, Sowers JR. Enhanced 24-hour norepinephrine and renin secretion in young patients with essential hypertension: Relation with the circadian pattern of arterial blood pressure. Am J Cardiol. 1985;55:112-115.
109. McClanahan M, Sowers JR, Beck FWJ, Mohanty PK, McKenzie T. Dopaminergic regulation of natriuretic response to acute volume expansion in dogs. Clin Sci. 1985;68:263-269.
110. Krishna GG, Danovitch GM, Beck FWJ, Sowers JR. Dopaminergic mediation of the natriuretic response to volume expansion. J Lab Clin Med. 1985;105(2):214-218.
111. Veldhuis JD, Sowers JR, Rogol AD, Klein FA, Miller N, Dufau ML. Pathophysiology of male hypogonadism associated with endogenous hyperestrogenism: Evidence for dual defects in the gonadal axis. New Engl J Med. 1985;312:1371-1375.
112. Beck FWJ, Sowers JR, Sicca D, Welch BG. Absent aldosterone response to metoclopramide in patients with high spinal cord transection: Evidence that metoclopramide stimulates aldosterone secretion through central pathways. Life Sci. 1985;36:2435-2444.
113. Sowers JR, Beck FWJ, Waters BK, Barrett JD, Welch BG. Studies of renin activation and regulation of aldosterone and 18-hydroxycorticosterone biosynthesis in hyporeninemic hypoaldosteronism. J Clin Endocrinol Metab. 1985;61:60-67.
114. Stern N, Sowers JR, Beahm E, McGinty D, Eggena P, Littner M, Nyby M, Catania R. Dissociation of 24 hour catecholamine levels from blood pressure in older men. Hypertension. 1985;7(6):1023-1029.
115. Weiskopf M, Braunstein GD, Bateman TM, Sowers JR, Conkllin CM, Matloff JM, Gray RJ. Adrenal function following coronary bypass surgery. Am Heart J. 1985;110:71-76.
116. Mohanty PK, Sowers JR, McNamara C, Welch B, Beck F, Thames MD. The effects of diltiazem on hormonal and hemodynamic responses to lower body negative pressure and tilt in patients with mild to moderate systemic hypertension. Am J Cardiol. 1985;56:28H-33H.
117. Mohanty PK, Sowers JR, Beck FW, Godschalk MF, Schmitt J, Newton M, McNamara C, Verbalis JG, McClanahan M. Catecholamine, renin, aldosterone,
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and arginine vasopressin responses to lower body negative pressure and tilt in normal man: Effects of bromocriptine. J Cardiovasc Pharamacol. 1985;7(6):1040-7.
118. Frishman WH, Kirkendall W, Lunn J, McCarron D, Moser M, Schnaper H, Smith LK, Sowers JR, Swartz S, Zawada E. Diuretics versus calcium-channel blockers in systemic hypertension: A preliminary multicenter experience with hydrochlorothiazide and sustained-release diltiazem. Am J Cardiol. 1985;56:92H-96H.
119. Naliboff BD, Cohen MJ, Sowers JR. Physiological and metabolic responses to brief stress in non-insulin dependent diabetic and control subjects. J Psychosomatic Res. 1985;29(4): 367-374.
120. Whitescarver SA, Holtzclaw BJ, Downs JH, Ott CE, Sowers JR, Kotchen TA. Effect of dietary chloride on salt-sensitive and renin-dependent hypertension. Hypertension. 1986; 8(1):56-61.
121. Mohanty PK, Sowers JR, Thames MD, Beck FWJ, Kawaguchi A, Lower RR. Myocardial norepinephrine, epinephrine and dopamine concentrations after cardiac autotransplantation in dogs. JACC. 1986;7:419-24.
122. Franklin SS, Sowers JR, Batzdorf U. Relationship between arterial blood pressure and plasma norepinephrine levels in a patient with neurogenic hypertension. Am J Med. 1986;81:1105-1107.
123. Gualdoni SM, Sowers JR. Dietary sodium and calcium in hypertension. Nutrition News. 1986;49(2).
124. Kasim S, Maxwell MM, Dornfeld L, Schroth P, Sowers JR. The effects of marked caloric restriction on lipoprotein lipase-activators in obese subjects. Nutrition Research. 1986;6:773-783.
125. Mohanty PK, Thames MD, Sowers JR. Influence of lower body negative pressure on plasma atrial natriuretic factor (ANF) in heart failure. Circulation. 1986;74:463-471.
126. Felicetta JV, Beck FWJ, Metz JA, McCarron DA, Sowers JR. Diet and catecholamines in the SHR. J Hypertension. 1986;4:S55-S57.
127. Zemel MB, Walsh MF, Standley P, Sowers JR. Effects of sodium and calcium on calcium metabolism and blood pressure regulation in hypertensive black adults. J Hypertension. 1986;4:S364-S366.
128. Zemel MB, Gualdoni SM, Sowers JR. Sodium excretion and plasma renin activity in normotensive and hypertensive black adults as affected by dietary calcium and sodium. J Hypertension. 1986;4(suppl 6):S343-S345.
129. Stern N, Sowers JR, McGinty D, Beahm E, Littner M, Catania R, Eggena P. Circadian rhythm of plasma renin activity in older normal and essential hypertensive men: Relation with inactive renin, aldosterone, cortisol and REM sleep. J Hyperten. 1986;4:543-550.
130. Sowers JR, Mohanty PK. Effect of advancing age on cardiopulmonary baroreceptor function in men. Hypertension. 1987;10:274-279.
131. Mohanty PK, Thames MD, Arrowood JA, Sowers JR, McNamara C, Szentpetery P. Impairment of cardiopulmonary baroreflex after cardiac transplantation in humans. Circulation. 1987;75(5):914-921.
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132. Tseng KM, Felicetta JV, Rydstedt LL, Sowers JR. Acute airway obstruction due to a benign cervical goiter. J Otolaryngology. 1987;97:72-75.
133. Sowers JR, Mohanty PK, Thames MD. Effect of advancing age on hemodynamic responses to lower body negative pressure in subjects with mild essential hypertension. J Cardiovasc Pharmacol. 1987;10(Suppl 4):S104-S106.
134. Mohanty PK, Sowers JR, Thames MD. Effect of hydrochlorothiazide and diltiazem on reflex vasoconstriction in hypertension. Hypertension. 1987;10(1):35-42.
135. Frishman WH, Zawada Jr. ET, Smith LK, Sowers JR, Swartz SL, Kirkendall W, Lunn J, McCarron D, Moser M, Schnaper H. Comparison of hydrochlorothiazide and sustained-released diltiazem for mild to moderate systemic hypertension. Am J Cardiol. 1987;59(6):615-623.
136. Mohanty PK, Sowers JR, McNamara C, Thames MD. Reflex vasoconstrictor responses to cardiopulmonary baroreceptor unloading, head up tilt, and cold pressor testing in mild to moderate elderly hypertensives: Effects of Clonidine. Cardiovasc Pharmacol. 1987;10(12):S135-S137.
137. Zemel MB, Gualdoni SM, Sowers JR. Reduction in total and extracellular water associated with calcium-induced natriuresis and the antihypertensive effect of calcium in blacks. Am J Hypertens. 1988;1:70-72.
138. Mohanty PK, Sowers JR, McNamara C, Thames MD. Reflex effects of prolonged cardiopulmonary baroreceptor unloading in humans. Am J Physiol. 1988;254:R320-R324.
139. Ellenbogen KA, Mohanty PK, Sowers JR, Walsh M, Thames MD. Atrial natriuretic factor release is enhanced by incremental atrial pacing. Am Heart J. 1988;116:489-495.
140. Weir M, Sowers JR. Physiologic and hemodynamic considerations in blood pressure control while maintaining organ perfusion. Am J Cardiol. 1988;61:60H-66H.
141. Zemel P, Gualdoni S, Sowers JR. Racial differences in mineral intake in ambulatory normotensives and hypertensives. Am J Hyperten. 1988;1:1465-1485.
142. Rezkalla S, Kloner RA, Sowers JR, Khatib R. ANP in acute coxsackievirus murine myocarditis. Am J Cardiol. 1988;61(15):1361-1362.
143. McGinty D, Beahm E, Stern N, Littner M, Sowers JR, Reige W. Nocturnal hypotension in older men with sleep-related breathing disorders. Chest. 1988;94(2):305-311.
144. Sowers JR, Zemel MB, Zemel P, Beck FW, Walsh MF, Zawada ET. Salt sensitivity in blacks: salt intake and natriuretic substances. Hypertension. 1988;12:485-490.
145. Sowers JR, Mohanty PK, Thames MD, Goldstein DS, Atlas S. Effects of atrial natriuretic factor on urinary concentration of catecholamines and renin secretion in dogs. Biochem Biophys Res Comm. 1988;156(3):1070-1076.
146. Zemel MB, Kraniak J, Standley PR, Sowers JR. Erythrocyte cation metabolism in salt-sensitive hypertensive blacks as affected by dietary sodium and calcium. Am J Hypertens. 1988;1:386-392.
147. Rezkalla S, Khatib R, Khadid G, Khan B, Haber E, Smith F, Walsh M, Sowers JR, Kloner R. Effect of indomethacin in the late phase of coxsackievirus myocarditis in a murine model. J Lab Clin Med. 1988;112:118-121.
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148. Sowers JR, Mohanty PK. Autonomic nervous system function in the elderly. Hypertension. 1988;6(suppl 1):S49-S54.
149. Brickman AS, Stern N, Sowers JR. Hypertension in pseudohypoparathyroidism type I. Am J Med. 1988; 85:785-92.
150. Zemel MB, Bedford BA, Zemel PC, Marwah O, Sowers JR. Altered cation transport in non-insulin-dependent diabetic hypertension: effects of dietary calcium. J Hypertension. 1988;6(suppl 4):S228-30.
151. Zakria F, Stern N, McGinty D, Beahm E, Littner M, Sowers JR. Effect of age on circadian rhythm of prolactin in normal men. Chronobiologia. 1988;15(3):219-222.
152. Zemel MB, Bedford BA, Standley PR, Sowers JR. Saline infusion causes rapid increase in parathyroid hormone and intracellular Ca levels. Am J Hypertens. 1989;2:185-87.
153. Sowers JR, Mohanty PK. Norepinephrine and forearm vascular resistance responses to tilt and cold pressor test in essential hypertension: Effects of aging. Angiology. 1989;40(10):872-879.
155. Zemel MB, Douglas F, Geiser R, Sowers JR. Effects of magnesium supplementation on erythrocyte cation transport in diuretic-treated hypertensives. Nutr Res. 1989;9:1285-1292.
156. Levy J, Zemel MB, Sowers JR. Role of cellular calcium metabolism in abnormalities in glucose metabolism and diabetic hypertension. Am J Med. 1989;87(6A):7S-16S.
157. Zemel P, Gualdoni S, Zemel MB, Allison T, Sowers JR. Age-associated changes in parathyroid hormone in black & caucasian males. J Human Hypertension. 1989;3:475-478.
158. Cushman P, Sowers JR. Alcohol withdrawal syndrome: clinical and hormonal responses to alpha 2-adrenergic agonist treatment. Alcohol Clin Exp Res. 1989;13(3):361-4.
159. Shehin SE, Sowers JR, Zemel MB. Impaired vascular smooth muscle 45Ca efflux and hypertension in Zucker obese rats. J Vasc Med Biol. 1989;1:278-282.
160. Levy J, Sowers JR, Zemel MB. Abnormal Ca-ATPase activity in erythrocytes of non-insulin dependent diabetic rats. Hormone Metab Res. 1990;22:136-140.
161. Sowers JR, Zemel MB, Walsh MF, Standley PR, Zemel PC, Bronsteen RA, Kraniak J, Sokol RJ. Effects of normal pregnancy on cellular cation metabolism and peripheral vascular resistance. Am J Hypertens. 1990;3:16-22.
162. Zemel PC, Urberg M, Zemel MB, Sowers JR. Metabolic and hemodynamic effects of magnesium supplementation in patients with essential hypertension. Am J Clin Nutr. 1990;51:665-669.
163. Bedford-Johnson BA, Sowers JR, Zemel PC, Luft FC, Zemel MB. Increased sodium-lithium countertransport in black non-insulin dependent diabetic hypertensives. Am J Hyperten. 1990;3:563-565.
164. Saunders E, Weir MR, Kong BW, Hollifield J, Sowers JR. A comparison of the efficacy and safety of a beta blocker, a calcium channel blocker and a converting enzyme inhibitor in hypertensive blacks. Arch Int Med. 1990;150:1707-1713.
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165. Reddy S, Shehin S, Sowers JR, Dardas G, Zemel M. Aortic 45Ca efflux and blood pressure regulation in streptozotocin-induced diabetic rats. J Vasc Med Biol. 1990;2:47-51.
166. Zemel MB, Sowers JR, Shehin S, Walsh MF, Levy J. Impaired calcium metabolism associated with hypertension in Zucker obese rats. Metabolism. 1990;39(7):704-708.
167. Zemel MB, Reddy S, Shehin S, Lockette W, Sowers JR. Vascular reactivity in Zucker obese rats: role of insulin resistance. J Vasc Med. 1990;2:81-85.
168. Zemel MB, Zemel PC, Bryg RB, Sowers JR. Dietary calcium induces regression of left ventricular hypertrophyin non-insulin-dependent diabetic blacks. Am J Hypertens. 1990;3:458-463.
169. Zemel MB, Zemel PC, Berry S, Norman G, Kowalcyk C, Sokol RJ, Standley PR, Walsh MF, Sowers JR. Altered platelet calcium metabolism as an early predictor of increased peripheral vascular resistance of preeclampsia in urban black women. N Engl J Med. 1990;323:434-438.
170. Luft FC, Zemel MB, Sowers JR, Fineberg NS, Weinberger MH. Sodium bicarbonate and sodium chloride: effects on blood pressure and electrolyte homeostasis in normal and hypertensive man. J Hypertens. 1990;8:663-670.
171. Zemel PC, Zemel MB, Sowers JR. Metabolic and hemodynamic effects of magnesium supplementation in patients with essential hypertension. Am J Clin Nutr. 1990;51(4):665-669.
172. Sowers JR, Zemel MB, Zemel PC, Standley PR. Calcium metabolism and dietary calcium in salt sensitive hypertension. Am J Hypertens. 1991;4:557-563.
173. Standley PR, Gangasani S, Prakash R, Zemel MB, Sowers JR. Human platelet calcium measurements: Methodological considerations and comparisons with calcium mobilization in vascular smooth muscle cells. Am J Hypertens. 1991;4:546-549.
174. Ambrozy SL, Shehin SE, Chiou C-Y, Sowers JR, Zemel MB. Effects of dietary calcium on blood pressure, vascular reactivity and vascular smooth muscle calcium efflux rate in Zucker rats. Am J Hypertens. 1991;4:592-596.
175. Standley PR, Ram JL, Sowers JR. Insulin attenuates vasopressin-induced calcium transients and a voltage-dependent calcium response in rat vascular smooth muscle cells. J Clin Invest. 1991;88:1230-1236.
176. Sowers JR. Is hypertension an insulin-resistant state? Metabolic changes associated with hypertension and antihypertensive therapy. Am Heart J. 1991;122:932-935.
177. Borhani NO, Bond MG, Sowers JR, Canossa-Etrris M, Buckalew V, Gibbons ME, Worthy AJ. The multicenter isradipine/diuretic atherosclerosis study: A study of the antiatherogenic properties of Isradipine in hypertensive patients. J Card Pharm. 1991;18(suppl 3):S15-S19.
178. Eisner GM, Johnson BF, McMahon FG, Rudd P, Sowers JR. A multicenter comparison of the safety and efficacy of isradipine and enalapril in the treatment of hypertension. Am J Hyperten. 1991;4(2 pt 2):154S-157S.
179. Eggena P, Sowers JR, Maxwell MH, Barrett JD, Golub MS. Hormonal correlates of weight loss associated with blood pressure reduction. Clin Exp Hyper - Theory and Practice. 1991;A13(8):1447-1456.
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180. Zemel MB, Reddy S, Sowers JR. Insulin attenuation of vasoconstrictor responses to phenylephrine in Zucker lean and obese rats. Am J Hyperten. 1991;4:537-9.
181. Zemel MB, Peuler JD, Sowers JR, Simpson L. Hypertension in insulin-resistant Zucker obese rats is independent of sympathetic neural support. Am J Phys. 1992; 262(Endocrinol Metab 25): E368-E371.
182. Khoury S, Yarows SA, O'Brien TK, Sowers JR. Ambulatory blood pressure monitoring in a nonacademic setting. Effects of age and sex. Am J Hyperten. 1992;5:616-623.
184. Jacobs DB, Sowers JR, Hmeidan A, Niyogi T, Simpson L, Standley PR. Effects of weight reduction on cellular cation metabolism and vascular resistance. Hypertension. 1993;21:308-314.
185. Sowers JR, Standley PR, Jacober S, Niyogi T, Simpson L. Postpartum abnormalities of carbohydrate and cellular calcium metabolism in pregnancy induced hypertension. Amer Jour of Hyper. 1993;6:302-307.
186. Sowers JR, Standley PR, Ram JL, Jacober S, Simpson L, Rose, K. Hyperinsulinemia, insulin resistance and hyperglycemia: Contributing factors in the pathogenesis of hypertension and atherosclerosis. Am J Hyperten. 1993;6:260S-270S.
187. Tirupattur PR, Ram JL, Standley PR, Sowers JR: Regulation of Na+,K+-ATPase gene expression by insulin in vascular smooth muscle cells. Am J Hyperten. 1993;6:626-629.
188. Sowers JR, Eggena P, Kowal DK, Simpson LL, Zhu J-H, Barrett JD. Expression of renin and angiotensinogen genes in preeclamptic and normal human placental tissue. Hypertens in Pregnancy. 1993;12(2):163-171.
189. Standley PR, Ram JL, Sowers JR. Insulin attenuation of vasopressin-induced calcium responses in arterial smooth muscle from Zucker rats. Endocrinology. 1993;133;4:1693-1699.
190. Standley PR, Ali S, Bapna C, Sowers JR. Increased platelet cytosolic calcium responses to low density lipoprotein in type II diabetes with and without hypertension. Am J Hyperten. 1993;6:938-943.
191. Peuler JD, Johnson BAB, Phare SM, Sowers JR. Sex-specific effects of an insulin secretagogue in stroke-prone hypertensive rats. Hypertension. 1993;22:214-220.
192. Ram JL, Fares MA, Standley PR, Therrell BS, Thyagaranjan RV, Sowers JR. Insulin inhibits vasopressin-elicited contraction of vascular smooth muscle cells. J Vascular Med Biol. 1993;4(5-6):250-254.
193. Sowers JR, Standley PR, Lewanczuk RZ, Pang PKT: Effects of weight reduction on circulating parathyroid hypertensive factor levels. Journ of Cardiovasc Pharmacol. 1994;23(suppl 2):S35-S37.
194. The National High Blood Pressure Education Program Working Group (Chair, James R. Sowers, MD). National high blood pressure education program working group report on hypertension in diabetes (Special Article). Hypertension 1994;23:145-158.
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195. Levy J, Gavin Jr, III, Sowers JR. Diabetes Mellitus: a disease of abnormal cellular calcium metabolism? Amer J Med. 1994;96:260-273 .
196. Yarows SA, Khoury S, Sowers JR. Cost effectiveness of 24-hour ambulatory blood pressure monitoring in evaluation and treatment of essential hypertension. Am J Hypertens. 1994;7:464-468.
197. Sowers JR, Sowers PS, Peuler JD. Role of insulin resistance and hyperinsulinemia in development of hypertension and atherosclerosis. J Lab Clin Med. 1994;123:647-652.
198. Zhang F, Ram JL, Standley PR, Sowers JR. 17-estradiol attenuates voltage-dependent Ca2+ currents in vascular smooth muscle. Am J Physiol. 1994;193:C975-C980.
199. Zhang F, Sowers JR, Ram JL, Standley PR, Peuler JD. Effects of pioglitazone on L-type calcium channels in vascular smooth muscle. Hypertension. 1994;24:170-175.
200. Levy MT, Jacober SJ, Sowers JR. Hypertensive disorders of pregnancy in southwestern Navajo Indians. Arch Int Med. 1994;154:2181-2183.
201. Jacober SJ, Morris DA, Sowers JR. Postpartum blood pressure and insulin sensitivity in African-American women with recent preeclampsia. Am J Hypertens. 1994;7:933-936.
202. Ravi J, Mantzoros CS, Prabhu AS, Ram JL, Sowers JR. In vitro relaxation of phenylephrine- and angiotensin II-contracted aortic rings by -estradiol. Am J Hypertens. 1994;7:1065-1069.
203. Simpson LL, Zhang F, Standley PR, Ram JL, Weir MR, Sowers JR. Role of calcium in vascular smooth muscle proliferation: antiproliferative effects of verapamil enantiomers - independence from calcium channel blockade. J Vasc Med Biol. 1994;5:46-53.
204. Standley PR, Rose KA, Sowers JR. Increased basal and arterial smooth muscle glucose transport in the Zucker rat. Am J Hypertens. 1995;8:48-52.
205. Sowers JR, Saleh AA, Sokol RJ. Hyperinsulinemia and insulin resistance are associated with preeclampsia in African Americans. Am J Hypertens. 1995;8:1-4.
206. Raman BB, Standley PR, Ram JL, Sowers JR. Effects of 1 7 estradiol and progesterone on platelet calcium responses. Am J Hypertens. 1995;8:197-200.
207. Dominguez LJ, Weinberger MH, Cefalu WT, Jacobs DB, Walsh MF, Barbagallo M, Sowers JR. Doxazosin improves insulin sensitivity and lowers blood pressure in type II diabetic hypertensives with no changes in tyrosine kinase activity or insulin binding. Am J Hypertens. 1995;8(5):528-532.
208. Sowers JR, Jacobs DB, Simpson LL, Al-Homsi B, Grunberger G, Sokol RJ. Erythrocyte insulin and insulin-like growth factor-I receptor tyrosine kinase activity in hypertension in pregnancy. Metabolism. 1995;44(10):1308-1313.
209. Mantzoros CS, Georgiadis EI, Young R, Khoury S, Evagelopoulou K, Katsilambros, Sowers JR. Relative androgenicity and blood pressure levels of young, healthy females. Am J Hypertens. 1995;8:606-614.
210. Jacober SJ, Sowers JR. Questions and answers: Exercise and Hypertension. JAMA. 1995;273(24):1965.
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211. Dominguez LJ, Barbagallo M, Kattah W, Garcia D, Sowers JR. Quinapril reduces microalbuminuria in essential hypertensive and in diabetic hypertensive subjects. Am J Hypertens. 1995;8:808-814.
212. Kloner RA, Sowers JR, DiBona GF, Gaffney M, Wein M, for the A CC T Study Group. Effect of amlodipine on left ventricular mass in the amlodipine cardiovascular community trial. J Cardiovasc Pharma. 1995;26:471-476.
213. Sowers JR, Epstein M. Diabetes mellitus and associated hypertension, vascular disease, and nephropathy: an update. Hypertension. 1995;26(part 1):869-879.
214. Standley PR, Zhang F, Ravi J, Ram JL, Sowers JR. Effects of SCN- substitution for Cl- on contractility, [Ca2+]i, and ionic currents in vascular smooth muscle. Life Sci. 1996;59(9):739-52.
215. Dominguez LJ, Davidoff AJ, Srinivas PR, Standley PR, Walsh MF, Sowers JR. Effects of metformin on tyrosine kinase activity, glucose transport, and intracellular calcium in rat vascular smooth muscle. Endocrinology. 1996;137:113-121.
216. Sowers JR, Raman BB, Afonso LC, Bedford-Rice K, Standley PR. Effects of intensive antihypertensive therapy on platelet cytosolic calcium responses to low density lipoprotein cholesterol. J Human Hypertens. 1996;10:177-180.
217. Kloner RA, Sowers JR, DiBona GF, Gaffney M, Wein M (for the Amlodipine Cardiovascular Community Trial Study Group). Sex- and age related antihypertensive effects of amlodipine. Am J Cardiol. 1996;77:713-722.
218. Walsh MF, Barazi M, Pete G, Muniyappa R, Dunbar JC, Sowers JR. Insulin-like growth factor I diminishes in vivo and in vitro vascular contractility: role of vascular nitric oxide. Endocrinology. 1996;137:1798-803.
219. Farrow S, Mahayni A, Banta G, Sowers JR, Lockette W. Metoclopramide does not inhibit atrial natriuretic factor-stimulated diuresis in man. Aviation, Space, & Environ Med. 1996;67(3):248-252.
220. Hu Y, Pete G, Walsh MF, Sowers JR, Dunbar JC. Central IGF-I decreases systemic blood pressure and increases blood flow in selective vascular beds. Horm Metab Res. 1996;28:211-214.
221. Sowers JR. Effects of insulin and IGF-I on vascular smooth muscle glucose and cation metabolism. Diabetes. 1996;45(suppl 3):S47-S51.
222. Borhani NO, Mercuri M, Borhani PA, Buckalew VM, Canossa-Terris M, Carr AA, Kappagoda T, Rocco MV, Schnaper HW, Sowers JR, Bond G. Final outcome results of the multicenter isradipine diuretic atherosclerosis study (MIDAS). A randomized controlled trial. JAMA. 1996;276:785-791.
223. Ren J, Dominguez LJ, Sowers JR, Davidoff AJ. Troglitazone attenuates high-glucose-induced abnormalities in relaxation and intracellular calcium in rat ventricular myocytes. Diabetes. 1996;45:1822-1825.
224. Sowers JR, Sokol RJ, Standley PR, Kruger M, Mason BA, Sowers PS, Cotton DB. Insulin resistance and increased body mass index in women developing hypertension in pregnancy. Nutr Metab Cardiovasc Dis. 1996;6:141-146.
225. Pete G, Hu Y, Walsh MF, Sowers JR, Dunbar JC. Insulin-like growth factor-1 decreases mean blood pressure and selectively increases regional blood flow in normal rats. PSEBM. 1996;213:187-192.
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226. Brown RA, Filipovich P, Walsh MF, Sowers JR. Influence of sex, diabetes and ethanol on intrinsic contractile performance of isolated rat myocardium. Basic Res Cardiol. 1996;91:353-360.
227. Peuler JD, Ravi J, Boggaram B, Taylor BL, Sowers JR. Interactive effects of insulin and dihydrotestosterone on adrenergic tone in isolated rat tail arterial rings. Am J Hypertens. 1996;9:860-866.
228. Song J, Standley PR, Zhang F, Joshi D, Gappy S, Sowers JR,Ram JL. Tamoxifen (estrogen antagonist) inhibits voltage-gated calcium current and contractility in vascular smooth muscle from rats. J Pharmacol Exp Therap. 1996;277:1444-1453.
229. Sowers JR. Insulin and insulin-like growth factor in normal and pathological cardiovascular physiology. Hypertension. 1997;29:691-699.
230. Song J, Walsh MF, Igwe R, Ram JL, Barazi M, Dominguez LJ, Sowers JR. Troglitazone reduces contraction by inhibition of vascular smooth muscle cell Ca2+ currents and not endothelial nitric oxide production. Diabetes. 1997;46(1):659-664.
231. Purzycki Z, Wyzkowski B, Gockowski K, Winnicki MM, Kazmirowicz M, Krupa-Wojciechowska B, Sowers JR. The influence of exercise on albumin excretion rate in borderline hypertensives and in offspring of hypertensive parents. J Human Hypertens. 1997;11:119-123.
232. Standley PR, Zhang F, Zayas RM, Muniyappa R, Walsh MF, Cragoe E, Sowers JR. IGF-1 regulation of Na+-K+-ATPase in rat arterial smooth muscle. Am J Physiol. 1997;273:E113-E121.
233. Muniyappa R, Walsh MF, Sowers JR. The role of IGF-1 and the effects of insulin on the vascular wall. Nutr Metab Cardiovasc Dis. 1997;7:86-91.
234. Muniyappa R, Walsh MF, Rangi JS, Zayas RM, Standley PR, Ram JL, Sowers JR. Insulin-like growth factor 1 increases vascular smooth muscle nitric oxide production. Life Sciences. 1997;61(9):925-931.
235. Peuler JD, Miller JA, Bourghli M, Zammam HY, Soltis EE, Sowers JR. Disparate effects of antidiabetic drugs on arterial contraction. Metabolism. 1997;46(10):1199-1205.
236. Muniyappa R, Srinivas PR, Ram JL, Walsh MF, Sowers JR. Calcium and protein kinase C mediate high glucose-induced inhibition of inducible nitric oxide synthase in vascular smooth muscle cells. Hypertension. 1998;31:289-295.
237. Skafar DF, Xu R, Morales J, Ram J, Sowers JR. Female sex hormones and cardiovascular disease in women. J Clin Endocrinol Metab. 1997; 82:3913-3918.
238. The Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure and the National High Blood Pressure Education Program Coordinating Committee. The Sixth Report (JNC-VI) of the Joint National Committee in Prevention, Detection, Evaluation and Treatment of High Blood Pressure. Arch Intern Med. 1997;157:2413-2446.
239. Sowers JR. Diabetes mellitus and cardiovascular disease in women. Arch Intern Med. 1998;158:617-621.
241. Sowers JR. Obesity and cardiovascular disease. Clin Chem. 1998;44:8(B)1821-1825.
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242. Hamaty M, Lamberti M, Sowers JR. Diabetic vascular disease and hypertension. Curr Opin in Cardiology. 1998;13:298-303.
243. Raman BB, Sowers JR. Evaluation and treatment of hypertension in diabetics. Hypertension in Diabetes. 1998;383-390.
244. Ren J, Walsh MF, Hamaty M, Sowers JR, Brown RA. Altered inotrophic response to IGF-1 in diabetic rat heart: influence of intracellular Ca2+ and NO. Am J Physiol. 1998;275:H823-H830.
245. Dominguez LJ, Barbagallo M, Sowers JR, Resnick LM. Magnesium responsiveness to insulin and insulin-like growth factor I in erythrocytes from normotensive and hypertensive subjects. J Clin Endocrinol Metab. 1998;83:4402-4407.
246. Byington RP, Furberg CD, Craven TE, Pahor M, Sowers JR. Isradipine in prediabetic hypertensive subjects. Diabetes Care. 1998;21:2103-2110.
247. Ali SS, Igwe RC, Walsh MF, Sowers JR. Troglitazone and vascular reactivity: role of glucose and calcium. Metabolism. 1999;48(1):125-130.
248. Ren J, Sowers JR, Natavio M, Brown RA. Influence of age on inotropic response to insulin and insulin-like growth factor 1 in spontaneously hypertensive rats: role of nitric oxide. PSEBM. 1999;221:46-52.
249. Sowers JR, Draznin B. Insulin, cation metabolism and insulin resistance. J Basic Clin Physiol Pharmacol. 1999;9(2-4):223-233.
250. Ren J, Walsh MF, Hamaty M, Sowers JR, Brown RA. Augmentation of the inotropic response to insulin in diabetic rat hearts. Life Sciences. 1999;65(4):369-380.
251. Grundy SM, Benjamin IJ, Burke GL, Chair A, Eckel RH, Howard BV, Mitch W, Smith SC, Sowers JR. Diabetes and cardiovascular disease. A statement for healthcare professionals from the American Heart Association. Circulation. 1999;100:1134-1146.
252. Ren J, Dominguez LJ, Sowers JR, Davidoff AJ. Metformin but not glyburide prevents high glucose-induced abnormalities in relaxation and intracellular Ca2+ transients in adult rat ventricular myocytes. Diabetes. 1999;48:2059-2065.
253. Jacober SJ, Sowers JR. An update on perioperative management of diabetes. Arch Intern Med. 1999;159:2405-2411.
254. Ren J, Samson WK, Sowers JR. Insulin-like growth factor 1 as a cardiac hormone: physiological and pathophysiological implications in heart disease. J Mol Cell Cardiol. 1999;31:2049-2061.
255. Ren J, Jefferson L, Sowers JR, Brown RA. Influence of age on contractile response to insulin-like growth factor 1 in ventricular myocytes from spontaneously hypertensive rats. Hypertension. 1999;34:1215-1222.
256. Hamaty M, Guzman CB, Walsh MF, Bode AM, Levy J, Sowers JR. High glucose-enhanced acetylcholine stimulated cGMP masks impaired vascular reactivity in tail arteries from short-term hyperglycemic rats. Int J Exp Diab Res. 2000;1:69-79.
257. Sowers JR, Lester M. Hypertension, hormones and aging. J Lab Clin Med. 2000;135:379-386.
258. Bakris GL, Williams M, Dworkin L, Elliott WJ, Epstein M, Toto R, Tuttle K, Douglas J, Hsueh W, Sowers JR for the National Kidney Foundation Hypertension and Diabetes Executive Committees Working Group. Preserving renal function in
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adults with hypertension and diabetes: A consensus Approach. Am J Kidney Dis. 2000;36(3):645-661.
259. Sowers JR. Common pathophysiological issues in diabetes and cardiovascular disease. Cardiol Rev. 2000;17(4):13-23.
260. Muniyappa R, Xu R, Ram JL, Sowers JR. Inhibition of Rho protein stimulates iNOS expression in rat vascular smooth muscle cells. Am J Physiol Heart Circ Physiol. 2000;278:H1762-H1768.
261. Sowers JR, Reed J. 1999 Clinical advisory treatment of hypertension and diabetes. J Clin Hypertens. 2000; 2:132-133.
262. Ren J, Walsh MF, Jefferson L, Natavio M, Iig KJ, Sowers JR, Brown RA. Basal and ethanol-induced cardiac contractile response in lean and obese Zucker rat hearts. J Biomed Sci. 2000;7:390-400.
263. Ren J, Sowers JR, Walsh MF, Brown RA. Reduced contractile response to insulin and IGF-1 in ventricular myocytes from genetically obese Zucker rats. Am J Physiol Physiol. 2000;279:H1708-1714.
264. The Board of Trustees of The North American Menopause Society (NAMS). Effects of menopause and estrogen replacement therapy or hormone replacement therapy in women with diabetes mellitus: Consensus opinion of the The North American Menopause Society. Menopause. 2000;7:87-95.
265. Muniyappa R, Srinivas PR, Ram JL, Sowers JR. Glucose-induced inhibition of inducible nitric oxide synthase in vascular smooth muscle cells - role of protein kinase C betaII and Rho. J Diabetes Complications. 2001;15(1):22.
266. Sowers JR. Hyperglycemia-related alterations in vascular nitric oxide production. J Diabetes Complications. 2001;15(1):6.
267. Guzman CB, Walsh M, Reddy V, Donthireddy V, Mahmood F, Bode A, Turner JR, Jacober SJ, Sowers JR. Altered myosin light-chain phosphorylation in resting platelets from premenopausal women with diabetes. Metabolism. 2001;50(2):151-156.
268. McFarlane SI, Banerji M, Sowers JR. Insulin resistance and cardiovascular disease. J Clin Endocrinol Metab. 2001;86(2):713-718.
269. Sowers JR, Epstein M, Frohlich ED. Diabetes, hypertension, and cardiovascular disease: An update. Hypertension. 2001;37:1053-1059.
270. Walsh MF, Ali SS, Sowers JR. Vascular insulin/insulin-like growth factor-1 resistance in female obese Zucker rats. Metabolism. 2001;50(5):607-612.
271. Winer N, Sowers JR, Weber MA. Gender differences in vascular compliance in young, healthy subjects assessed by pulse contour analysis. J Clin Hypertens. 2001;3:145-152.
272. Qin D, Huang B, Deng L, El-Adawi H, Ganguly K, Sowers JR, El-Sherif N. Downregulation of K+ channel genes expression in type I diabetic cardiomyopathy. BBRC. 2001;283:549-553.
273. Isenovic E, Muniyappa R, Milivojević N Rao Y, Sowers JR. Role of PI3-kinase in isoproterenol and IGF-1 induced ecNOS activity. BBRC. 2001;285:954-958.
274. Hintz KK, Wold LE, Colligan PB, Scott GI, Lee KJ, Sowers JR, Ren J. Influence of ovariectomy on ventricular myocyte contraction in simulated diabetes. J Biomed Sci. 2001;8:307-313.
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275. Xu R, Sowers JR, Skafar DF, Ram JL. Hydrocortisone modulates the effect of estradiol on endothelial nitric oxide synthase expression in human endothelial cells. Life Sciences. 2001;69:2711-2817.
276. Isenovic E, Walsh MF, Muniyappa R, Bard M, Diglio CA, Sowers JR. Phosphatidylinositol 3-Kinase may mediate isoproterenol-induced vascular relaxation in part through nitric oxide production. Metabolism. 2002;51(3):380-386.
277. McFarlane SI, Muniyappa R, Francisco R, Sowers JR. Pleiotropic effects of statins: lipid reduction and beyond. J Clin Endocrinol Metab. 2002;87:1451-1458.
278. Apedo MT, Sowers JR, Banerji MA. Cardiovascular disease in adolescents with type 2 diabetes mellitus. J Pediatr Endocrinol Metab. 2002;15:519-523.
279. McFarlane SI, Jacober SJ, Winer N, Kaur J, Castro JP, Wui MA, Gliwa A, Von Gizycki H, Sowers JR. Control of cardiovascular risk factors in patients with diabetes and hypertension at urban academic medical centers. Diabetes Care. 2002;25(4):718-723.
280. Kirpichnikov D, McFarlane SI, Sowers JR. Metformin: An Update. Ann Intern Med. 2002;137:25-33.
281. Sowers JR. Hypertension, angiotensin II, and oxidative stress. N Engl J Med. 2002;346(25):1999-2001.
282. Sowers, JR. Endothelial vasolidation effects of statins in type 2 diabetic patients: response to van Venrooij et al. Diabetes Care. 2002;25(7):1242-1243.
283. Sowers JR, Ferdinand KC, Bakris GL, Douglas JG. Hypertension-related disease in Africian Americans. Postgrad Med. 2002;112(4):24-48.
284. Douglas JG, Ferdinand KC, Bakris GL, Sowers JR. Barriers to blood pressure control in African Americans. Postgrad Med. 2002;112(4)51-70.
285. Bakris GL, Ferdinand KC, Douglas JG, Sowers JR. Optimal treatment of hypertension in African Americans. Postgrad Med. 2002;112(4):73-84.
286. Isenovic E, Meng Y, Divald A, Milivojevic N, Sowers JR. Role of phosphatidylinositol 3-kinase/Akt pathway in angiotensin II and insulin-like growth factor-1 modulation of nitric oxide synthase in vascular smooth muscle cells. Endocrine. 2002;19(3):287-292.
287. Sowers JR, Haffner S. Treatment of cardiovascular and renal risk factors in the diabetic hypertensive. Hypertension. 2002;40:781-788.
288. Grundy SM, Garaber A, Goldberg R, Havas S, Holman R, Lamendola C, Howard WJ, Savage P, Sowers JR, Vega GL. Prevention Conference VI. Diabetes and cardiovascular disease. Writing Group IV: Lifestyle and medical management of risk factors. Circulation. 2002;105:e153-e158.
289. Isenovic ER, Divald A, Milivojevic N, Grgurevic T, Fisher SE, Sowers JR. Interactive effects of insulin-like growth factor-1 and -estradiol on endothelial nitric oxide synthase activity in rat aortic endothelial cells. Metabolism. 2003;52(4):482-487.
290. Douglas JG, Bakris GL, Epstein M, Ferdinand KC, Ferrario C, Flack JM, Jamerson KA, Jones WE, Haywood J, Maxey R, Ofili EO, Saunders E, Shiffrin EL, Sica DA, Sowers JR, Vidt DG. Hypertension in African Americans Working Group of the International Society on Hypertension in Blacks. Management of high blood pressure in African Americans: consensus statement of the Hypertension in African
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Americans Working Group of the International Society on Hypertension in Blacks. Arch Intern Med. 2003;163(5):525-541.
291. Privratsky JR, Wold LE, Sowers JR, Quinn MT, Ren J. AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase. Hypertension. 2003; 42(2):206-212.
292. Tramontano AF, Muniyappa R, Black AD, Blendea MC, Cohen I, Deng L, Sowers JR, Cutaia MV, El-Sherif N. Erythropoietin protects cardiac myocytes from hypoxia-induced apoptosis through an Akt-dependent pathway. Biochem Biophys Res Commun. 2003;308(4):990-994.
293. Isenovic ER, Jacobs DB, Kedees MH, Sha Q, Milivojevic N, Kawakami K, Gick G, Sowers JR. Ang II regulation of the Na+ pump involves the PI3K and p42/44 MAPK signaling pathways in VSMC. Endocrinology. 2004;145(3):1151-60.
294. Sowers JR. Insulin resistance and hypertension. Am J Physiol Heart Circ Physiol. 2004;286:H1597-H1602.
295. Bakris GL, Sowers JR. When does new onset diabetes resulting from antihypertensive therapy increase cardiovascular risk. Hypertension. 2004;43(5):941-942.
296. Isenovic ER, Meng Y, Jamali N, Milivojevic N, Sowers JR. Ang II attenuates IGF-1 stimulated Na+, K+-ATPase activity via P13K/Akt pathway in vascular smooth muscle cells. Int J Mol Med. 2004;13(6):915-22.
297. Sowers, JR. Estrogen-inducible cytoskeletal linker protein ezrin interaction with the low-density lipoprotein receptor. Endocrinology. 2004;145(7):3074-75.
298. McFarlane SI, Castro J, Kaur J, Shin JJ, Kelling D Jr, Faraq A, Simon N, El-Atat F, Sacerdote A, Basta E, Flack J, Bakris G, Sowers JR. Control of blood pressure and other cardiovascular risk factors at different practice settings: outcomes of care provided to diabetic women compared to men. J Clin Hypertens. 2005;7(2):73-80.
299. Brooks CS, Sowers JR. Importance of achieving lower blood pressure in hypertensive patients with diabetes. Hypertension. 2004;44(5):614-5.
300. Blendea MC, Jacobs D, Stump CS, McFarlane SI, Ogrin C, Bahtyiar G, Stas S, Kumar P, Sha O, Ferrario CM, Sowers JR. Abrogation of oxidative stress improves insulin sensitivity in the Ren2 rat model of tissue angiotensin II overexpression. Am J Physiol Endocrinol Metab. 2005;288(2):E353-9.
301. Sowers JR, White WB, Pitt B, Whelton A, Simon LS, Winer N, Kivitz A, van Ingen H, Brabant T, Fort JG. The effects of cyclooxygenase-2 inhibitors and non-steroidal anti-inflammatory therapy on 24-hour blood pressure in patients with hypertenstion, osteoarthritis, and type 2 diabetes mellitus. Arch Intern Med. 2005;165:161-168.
302. Hayden MR, Whaley-Connell A, Sowers JR. Renal redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic nephropathy: paying homage to the podocyte. Am J Nephrol. 2005;25(6):553-569.
303. Blendea MC, Bard M, Sowers JR. High-fat meal impairs vascular compliance in a subgroup of young healthy subjects. Metabolism. 2005;54(10):1337-44.
304. Sowers JR, Nuetel JM, Saunders E, Bakris GL, Cushman WC, Ferdinand KC, Ofili EO, Weber MA, INCLUSIVE Investigators. Antihypertensive efficacy of
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irbesartan/HCTZ in men and women with the metabolic syndrome and type 2 diabetes. J Clin Hypertens. 2006;8(7):470-80.
305. McFarlane SI, Rundek T, Nicasio J, Deshmukh M, Sowers JR. The DREAM trial and the prospect of diabetes prevention. Curr Diab Rep. 2006;6(3):205-6.
306. Whaley-Connell A, Sowers JR. Chronic kidney disease and the cardiometabolic syndrome. J Clin Hypertens. 2006;8(8):546-8.
307. Whaley-Connell A, Chowdhury N, Hayden MR, Stump CS, Habibi J, Wiedmeyer CE, Gallagher PE, Tallant EA, Cooper SA, Link CD, Ferrario CM, Sowers JR. Oxidative stress and glomerular filtration barrier injury: role of the renin-angiotensin system in the Ren 2 transgenic rat. Am J Physiol Renal Physiol. 2006;291(6):F1308-14.
308. Ofili EO, Ferdinand KC, Saunders E, Neutel JM, Bakris GL, Cushman WC, Sowers JR, Weber MA. Irbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapy. J Natl Med Assoc. 2006;98(4):618-26.
309. Hayden MR, Chowdhury NA, Cooper SA, Whaley-Connell A, Habibi J, Witte L, Wiedmeyer C, Manrique CM, Lastra G, Ferrario C, Stump C, Sowers, JR. Proximal tubule microvilli remodeling and albuminuria in the Ren2 transgenic rat . Am J Physiol Renal Physiol. 2006;292:F861-F867.
310. Stump CS, Henriksen EJ, Wei Y, Sowers JR. The metabolic syndrome: role of skeletal muscle metabolism. Ann Intern Med. 2006;38(6):389-402.
311. Wei Y, Sowers JR, Nistala R, Gong H, Uptergrove GM, Clark SE, Morris EM, Szary N, Manrique C, Stump CS. Angiotensin II Induced NADPH oxidase activation impairs insulin signaling in skeletal muscle cells. J Biol Chem. 2006;281:35137-35146.
312. Bakris G, Molitch M, Sowers JR. Differences in glucose tolerance between fixed-dose antihypertensive drug combinations in people with metabolic syndrome. The STAAR Study. Diabetes Care. 2006;29:2592-2597.
313. Lastra G, Manrique C, Sowers JR. Obesity, cardiometabolic syndrome, and chronic kidney disease: the weight of the evidence. Adv Chronic Kidney Dis. 2006;4:365-73.
314. Govindarajan G, Hayden MR, Cooper SA, Figueroa SD, Ma L, Hoffman TJ, Stump CS, Sowers JR. Metabolic derangements in the insulin-resistant heart. J Cardiometab Syndr. 2006;1(2):102-6.
315. Rai A, Whaley-Connell A, McFarlane S, Sowers JR. Hyponatremia, arginine vasopressin dysregulation and vasopressin receptor antagonism. Am J Nephrol. 2006;26(6):579-589
316. Stump CS, Sowers JR, Thomson SP. Obesity: are we prepared to act? J Cardiometab Syndr. 2007;2(1):5-7.
317. Whaley-Connell AT, Wei Y, Hayden MR, Habibi J, Stump CS, Sowers JR. Albumin activation of NAD(P)H oxidase activity is mediated via Rac1 in proximal tubule cells. Am J Nephrol. 2007;27(1):15-23.
318. McFarlane S, Gizyckia H, Salifua M, Deshmukha M, Manierama M, Gebreegziabhera Y, Gliwa A, Bordiaa A, Shaha S, Sowers J. Alcohol consumption and blood pressure in the adult US population: assessment of gender-related effects. J Hyper. 2007;25:965-970.
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319. Hayden, MR, Karuparthi PR, Manrique CM, Lastra G, Habibi J, Sowers JR. Longitudinal ultrastructure study of islet amyloid in the HIP rat model of type 2 diabetes mellitus. Exper Biol Med. 2007;232(6):772-9.
320. Karuparthi PR, Yerram P, Lastra G, Hayden MR, Sowers JR. Understanding essential hypertension from the perspective of the cardiometabolic syndrome. J Am Soc Hypertension. 2007;1(2):120-134.
321. Whaley-Connell A, Govindarajan G, Habibi J, Hayden J, Cooper S, Wei Y, Ma L, Qazi M, Link D, Stump C, Karuparthi P, Ferrario C, Sowers J. Angiotensin-II mediated oxidative stress impairs Akt activation and promotes myocardial tissue remodeling in the transgenic TG (mRen2) 27 Ren2 rat. Am J Physiol Endocrinol Metab. 2007;293:E355-E363.
322. Sowers JR. Metabolic risk factors and renal disease. Kidney Int. 2007;71(8):719-20.
323. Khan U, Sowers, JR. Cardiometabolic syndrome and thyroid dysfunction. J Cardiometabolic syndrome. 2007;2(2):81-83.
324. Habibi J, Whaley-Connell A, Qazi MA, Hayden MR, Cooper SA, Tramontano A, Thyfault J, Stump C, Ferrario C, Muniyappa, R, Sowers JR. Rosuvastatin, a 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitor, decreases cardiac oxidative stress and remodeling in Ren2 transgenic rats. Endocrinology. 2007; 148(5):2181-8.
325. Stas S, Whaley-Connell A, Habibi J, Appesh L, Hayden MR, Karuparthi PR, Qazi M, Morris EM, Cooper S, Link CD, Stump C, Hay M, Ferrario C, Sowers JR. Mineralocorticoid receptor blockade attenuates chronic overexpression of the renin-angiotensin-aldosterone system stimulation of NADPH oxidase and cardiac remodeling. Endocrinology. 2007;148(8):3773-3780.
326. Wei, Y, Whaley-Connell AT, Chen K, Habibi J, Uptegrove SE, Stump CS, Ferrario CM, Sowers JR. NADPH oxidase contributes to vascular inflammation insulin resistance, and remodeling in the transgenic (mRen2) rat. Hypertension. 2007;50:384-391.
327. Moser M, Sowers JR, Black HR. Microalbuminuria, chronic renal disease, and the effects of the metabolic syndrome on cardiovascular events. J Clin Hypertens (Greenwich). 2007;9(7):551-6.
328. Sowers, JR. The role of C-reactive protein in the metabolic syndrome and diabetes mellitus. The Endocrinologist. 2007;17(3):163-8.
329. Hayden MR, Sowers JR. Redox imbalance in diabetes. Antioxid Redox Signal. 2007;9 (7):865-7.
330. Hayden MR, Sowers JR. Isletopathy in type 2 diabetes mellitus: Implications of islet RAs, islet fibrosis, islet amyloid, remodeling, and oxidative stress. Antioxid Redox Signal. 2007;9(7): 891-910.
331. Sowers, JR. Hypertension myocardial fibrosis. J Clin Hypertens. 2007;9(7):558-9.
332. Cooper SA, Whaley-Connell A, Habibi J, Wei Y, Lastra G, Manrique C, Stas S, Sowers JR. Renin-angiotensin-aldosterone system and oxidative stress in cardiovascular insulin resistance. Am J Physiol Heart Circ Physiol. 2007;293:H2009-H2023.
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333. Hayden MR, Chowdhury NA, Witte L, Sowers JR. Microalbuminuria and proximal tubule remodeling in the cardiometabolic syndrome. J Cardiometab Syndr. 2006;1(2):107-14.
334. Hayden MR, Karuparthi PR, Habibi J, Wasekar C, Lastra G, Manrique C, Stas S, Sowers JR. Ultrastructural islet study of early fibrosis in the Ren2 Rat model of hypertension. Emerging role of the islet pancreatic pericyte-stellate cell. JOP. J Pancreas (Online). 2007;8(6):725-738.
335. Sowers JR, Bakris GL, Black HR, Giles TD. The cardiometabolic syndrome and calcium channel blocker combination drugs. J Cardiometab Syndr. 2007;2(3):207-12.
336. Hayden MR, Karuparthi PR, Manrique CM, Latra G, Habibi J, Sowers JR. Longitudinal ultrastructure study of islet amyoid in the HOP rat model of type 2 diabetes mellitus. Exp Biol Med. 2007;232:772-9.
337. Lastra-Gonzalez G, Manrique-Acevedo C, Sowers JR. New trends in insulin resistance: the role of mineralocorticoids. J Cardiometab Syndr. 2007;2(4):233-4.
338. Thompson SP, Stump CS, Kurukulasuriya LR, Sowers JR. Adrenal steriods and the metabolic syndrome. Current Hypertension Reports. 2007;9:512-519.
339. Winer N, Sowers JR. Diabetes and arterial stiffening. Adv Cardio. 2007; 44:245-51.
340. Whaley-Connell A, DeMarco VG, Lastra G, Manrique C, Nistala R, Cooper SA, Westerly B, Hayden MR, Wiedmeyer C, Wei Y, Sowers JR. Insulin resistance, oxidative stress, and podocyte injury: role of rosuvastatin modulation of filtration barrier injury. Am J Nephrol. 2008;28(1):67-75.
341. Wei Y, Sowers JR, Clark SE, Li W, Ferrario CM, Stump CS. Angiotensin II-induced skeletal muscle insulin resistance is mediated by NF-{kappa}B activation via NADPH oxidase. Am J Physiol Endocrinol Metab. 2008;294(2):E345-51.
342. Kim J, Wei Y, Sowers JR. Role of mitochondrial dysfunction in insulin resistance. Circ Res. 2008; 102:401-14.
343.Wei Y, Whaley-Connell AT, Stump CS, Sowers JR. Skeletal muscle insulin resistance: role of inflammatory cytokines and reactive oxygen species. Am J Physiol Regul Integr Comp Physiol. 2008;294(3):R673-80.
344. Ren J, Duan J, Thomas DP, Yang X, Sreejayan N, Sowers JR, Leri A, Kajstura J, Gao F, Anversa P. IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction. Am J Physiol Regul Integr Comp Physiol. 2008;294(3):R793-802.
345. Whaley-Connell A, Sowers JR. Obesity, insulin resistance, and nocturnal systolic blood pressure. Hypertension. 2008;51(3):620-1.
346. Stas S, Whaley-Connell AT, Sowers JR. Aldosterone and hypertension in the cardiometabolic syndrome. J Clin Hypertens. 2008;10(2):94-6.
347. DeMarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Heller RL, Bosanquet JP, Hayden MR, Delcour K, Cooper SA, Andresen BT, Sowers JR, Dellsperger KC. Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat. Am J Physiol Heart Circ Physiol. 2008;294(6):H2659-68.
348. Bakris G, Molitch M, Zhou Q, Sarafidis P, Champion A, Bacher P, Sowers JR, for the study of Trandolapril/Verapamil SR and Insulin Resistance Investigators. Reversal of diuretic-associated impaired glucose tolerance and new-onset
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diabetes: Results of the STAR-LET Study. J Cardiometab Syndr. 2008;3(1):18-25.
349. Whaley-Connell AT, Sowers JR, McFarlane SI, Norris KC, Chen SC, Li S, Qiu Y, Wang C, Stevens LA, Vassalotti JA, Collins AJ; Kidney Early Evaluation Program Investigators. Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004. Am J Kidney Dis. 2008;51(4 Suppl 2):S21-9.
350. Accurso A, Bernstein RK, Dahlqvist A, Draznin B, Feinman RD, Fine EJ, Gleed A, Jacobs DB, Larson G, Lustig RH, Manninen AH, McFarlane SI, Morrison K, Nielsen JV, Ravnskov U, Roth KS, Silvestre R, Sowers JR, Sundberg R, Volek JS, Westman EC, Wood RJ, Wortman J, Vernon MC. Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal. Nutr Metab. 2008;5:9.
351. Lastra G, Whaley-Connell A, Manrique CM, Habibi J, Gutweiler A, Appesh L, Hayden MR, Wei Y, Ferrario CM, Sowers JR. Low-dose spironolactone reduces reactive oxygen species generation and improves insulin stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat. Am J Physiol Endocrinol Metab. 2008; 295(1):E110-16.
352. Whaley-Connell A, Habibi J, Cooper S, DeMarco V, Hayden MR, Stump C, Link D, Ferrario C, Sowers JR. Effect of renin inhibition and AT1R Blockade on Myocardial Remodeling in the transgenic Ren2 rat. Am J Physiol Endocrinol Metab. 2008;295(1):E103-9.
353. Wei, Y, Clark SE, Morris EM, Thyfault JP, Uptergrove GM, Whaley-Connell AT, Ferrario CM, Sowers JR, Ibdah JA. Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG (mRen2)27(Ren2) rats. J Hepatol. 2008;49(3):417-28.
354. Hayden MR, Karuparthi PR, Habibi J, Lastra G, Patel K, Wasekar C, Manrique CM, Ozerdem U, Stas S, Sowers JR. Ultrastructure of islet microcirculation, pericytes and the islet exocrine interface in the HIP rat model of diabetes. Exp Biol Med (Maywood). 2008;233(9):1109-23.
355. Habibi J, Whaley-Connell A, Hayden MR, Demarco VG, Schneider R, Sowers DS, Karuparthi P, Ferrario CM, Sowers JR. Renin inhibition attenuates insulin resistance, oxidative stress, and pancreatic remodeling in the transgenic Ren2 rat. Endocrinology. 2008;149(11):5643-53.
356. Whaley-Connell A, Cooper SA, Karuparthi PR, Hayden MR, Rehmer N, DeMarco VG, Andresen BT, Wei Y, Ferrario C, Sowers JR. Attenuation of NADPH oxidase activation and glomerular filtration barrier remodeling with statin treatment. Hypertension. 2008;51(2):474-80.
357. Sowers JR, Lastra G, Rocha R, Seifu Y, Crikelair N, Levy DG. Initial combination therapy compared with monotherapy in diabetic hypertensive patients. J Clin Hypertens (Greenwich). 2008;10(9):668-76.
358. Bakris GL, Sowers JR; American Society of Hypertension Writing Group. ASH position paper: treatment of hypertension in patients with diabetes-an update. J Clin Hypertens (Greenwich). 2008;10(9):707-13; discussion 714-5.
359. Gardner M, Gardner DW, Sowers JR. The cardiometabolic syndrome in the adolescent. Pediatr Endocrinol Rev. 2008;5 Suppl 4:964-8.
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360. Hayden MR, Sowers JR. Pancreatic renin-angiotensin-aldosterone system in the cardiometabolic syndrome and type 2 diabetes mellitus. J Cardiometab Syndr. 2008;3(3):129-31.
361. Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell AT, Sowers JR. Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy. Am J Physiol Heart Circ Physiol. 2009;296(4):H1184-92.
362. Morris EM, Whaley-Connell AT, Thyfault JP, Britton SL, Koch LG, Wei Y, Ibdah JA, Sowers JR. Aerobic capacity and high-fat diet contribute to oxidative stress and IRS-1 degradation in the kidney. Am J Nephrol. 2009;30(2):112-119.
363. Wei Y, Whaley-Connell A, Sowers JR, et al. Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing Akt activation. Hypertension. 2009;53(2):158-65.
364. Lastra G, Habibi J, Whaley-Connell AT, Manrique C, Hayden MR, Rehmer J, Patel K, Ferrario C, Sowers JR. Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression. Endocrinology. 2009;150(6):2561-8.
365. Wei Y, Clark SE, Thyfault JP, Uptergrove GM, Li W, Whaley-Connell AT, Ferrario CM, Sowers JR, Ibdah JA. Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats. Am J Pathol. 2009; 174(4):1329-37.
366. Whaley-Connell A, Habibi J, Wei Y, Gutweiler A, Jellison J, Wiedmeyer CE, Ferrario CM, Sowers JR. Mineralcorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat. Am J Physiol Renal Physiol. 2009;296(5):F1013-22.
367. Whaley-Connell A, Sowers JR, McCullough PA, Roberts T, McFarlane SI, Chen SC, Li S, Wang C, Collins AJ, Bakris GL; KEEP Investigators. Diabetes mellitus and CKD awareness: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES). Am J Kidney Dis. 2009;53(4 Suppl 4):S11-21.
368. Salifu MO, Shah S, Iqbal MH, Nabi M, Hayat A, Whaley-Connell AT, Sowers JR, McFarlane SI. Effect of Ethnicity on the Progression of Diabetic Kidney Disease Independent of Glycemic Control. Am J Nephrol. 2009;30(3):261-267.
369. Manrique C, Whaley-Connell A, Sowers JR. Nebivolol in obese and non-obese hypertensive patients. J Clin Hypertens (Greenwich). 2009;11(6):309-15.
370. Whaley-Connell A, Habibi J, Johnson M, Tilmon R, Rehmer N, Rehmer J, Wiedmeyer C, Ferrario CM, Sowers JR. Nebivolol Reduces Proteinuria and Renal NADPH Oxid+ase-Generated Reactive Oxygen Species in the Transgenic Ren2 Rat. Am J Nephrol. 2009;30(4):354-360.
371. Demarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Sowers JR, Andresen BT, Gutweiler AA, Ma L, Johnson MS, Ferrario CM, Dellsperger KC. Rosuvastatin Ameliorates the Development of Pulmonary Arterial Hypertension in the TG(mRen2)27 Rat. Am J Physiol Heart Circ Physiol. 2009:297(3):H1128-39.
372. Whaley-Connell A, Sowers JR. Hypertension and Insulin Resistance. Hypertension. 2009;54(3):462-4.
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373. Sowers JR. Joint publication of journal of the CardioMetabolic Syndrome and the Journal of Clinical Hypertension. J Clin Hypertens (Greenwich). 2009 Sep;11(9):504.
374. Saab G, Whaley-Connell A, McFarlane SI, Li S, Chen SC, Sowers JR, McCullough PA, Bakris GL; Kidney Early Evaluation Program Investigators. Obesity is associated with increased parathyroid hormone levels independent of glomerular filtration rate in chronic kidney disease. Metabolism. 2009;59(3):385-389.
375. Allcock DM, Gardner MJ, Sowers JR. Relation between Childhood Obesity and Adult Cardiovascular Risk. Int J Pediatr Endocrinol. 2009;2009:108187.
376. Hanna-Moussa A, Gardner MJ, Kurukulasuriya LR, Sowers JR. Dysglycemia/Prediabetes and cardiovascular risk factors. Rev Cardiovasc Med. 2009;10(4):202-8.
377. Manrique C, Johnson M, Sowers JR. Thiazide Diuretics Alone or With {beta}-Blockers Impair Glucose Metabolism in Hypertensive Patients With Abdominal Obesity. Hypertension. 2010;55(1):61-8.
378. Zhou X, Ma L, Habibi J, Whaley-Connell A, Hayden MR, Tilmon RD, Brown AN, Kim JA, Demarco VG, Sowers JR. Nebivolol Improves Diastolic Dysfunction and Myocardial Remodeling Through Reductions in Oxidative Stress in the Zucker Obese Rat. Hypertension. 2010;55(4):880-8
379. Hayden MR, Habibi J, Whaley-Connell A, Sowers D, Johnson M, Tilmon R, Jain D, Ferrario C, Sowers JR. Nebivolol Attenuates Maladaptive Proximal Tubule Remodeling in Transgenic Rats. Am J Nephrol. 2010;31(3):262-272.
380. Whaley-Connell A, Pavey BS, McCullough PA, Saab G, Li S, McFarlane SI, Chen SC, Vassalotti JA, Collins AJ, Bakris G, Sowers JR; KEEP Investigators. Dysglycemia predicts cardiovascular and kidney disease in the Kidney Early Evaluation Program. J Clin Hypertens (Greenwich). 2010;12(1):51-8.
381. Whaley-Connell A, Nistala R, Habibi J, Hayden MR, Schneider RI, Johnson MS, Tilmon R, Rehmer N, Ferrario CM, Sowers JR. Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat. Am J Physiol Renal Physiol. 2010;298(3):F655-61.
382. DeMarco VG, Johnson MS, Whaley-Connell AT, Sowers JR. Cytokine abnormalities in the etiology of the cardiometabolic syndrome. Curr Hypertens Rep. 2010 Apr;12(2):93-8.
383. Bakris GL, Sowers JR, Glies TD, Black HR, Izzo JL Jr, Materson BJ, Oparil S, Weber MA. Treatment of hypertension in patients with diabetes--an update. J Am Soc Hypertens. 2010;4(2):62-7.
385. Figueroa SC, Khan U, Kurukulasuriya LR, Gardner D, Sowers JR. Surgical Cure of Hypertension in a Patient With MEN 2A Syndrome and Mixed Dopamine, Metanephrine Pheochromocytoma. J Clin Hypertens (Greenwich). 2010;12(6):439-43.
386. Bomback AS, Rekhtman Y, Whaley-Connell AT, Kshirsagar AV, Sowers JR, Chen SC, Li S, Chinnaiyan KM, Bakris GL, McCullough PA. Gestational diabetes alone,
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in the absence of subsequent diabetes, is associated with microalbuminuria: results from the Kidney Early Evaluation Program (KEEP). Diabetes Care. 2010 Dec;33(12):2586-91.
387. Varagic J, Ahmad S, Brosnihan KB, Habibi J, Tilmon RD, Sowers JR, Ferrario CM. Salt-Induced Renal Injury in Spontaneously Hypertensive Rats: Effects of Nebivolol. Am J Nephrol. 2010;32(6):557-566.
388. Whaley-Connell A, Sowers JR. Is it Time to Target Prehypertension. Cardiovasc Ther. 2010;28(6):337-8.
389. Siyam F, Brietzke SA, Sowers JR. Resistant hypertension in office practice: a clinical approach. Hosp Pract (Minneap). 2010;38(4):90-7.
390. Demarco VG, Whaley-Connell AT, Sowers JR, Habibi J, Dellsperger KC. Contribution of oxidative stress to pulmonary arterial hypertension. World J Cardiol. 2010 Oct 26;2(10):316-24.
391. McCullough PA, Whaley-Connell A, Brown WW, Collins AJ, Chen SC, Li S, Norris KC, Jurkovitz C, McFarlane S, Obialo C, Sowers JR, Stevens L, Vassalotti JA, Bakris GL. Cardiovascular risk modification in participants with coronary disease screened by the Kidney Early Evaluation Program. Intern Med J. 2010 Dec;40(12):833-41.
392. Oparil S, Giles T, Ofili EO, Pitt B, Seifu Y, Hilkert R, Samuel R, Sowers JR. Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy. J Hypertens. 2011 Jan;29(1):161-70.
393. Demarco VG, Johnson MS, Habibi J, Pulakat L, Gul R, Hayden MR, Tilmon R, Dellsperger KC, Winer N, Whaley-Connell AT, Sowers JR. Comparative analysis of telmisartan and olmesartan on cardiac function in the TG(mRen2)27 rat. Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H181-90.
395. Sowers JR. The heart and the kidneys: partners in disease? Cardiorenal Med. 2011;1:1-2.
396. Whaley-Connell A, Pulakat L, DeMarco VG, Hayden MR, Habibi J, Henriksen EJ, Sowers JR. Overnutrition and the cardiorenal syndrome: use of a rodent model to examine mechanisms. Cardiorenal Med. 2011;1:23-30.
397. Weir MR, Zappe D, Orloski LA, Sowers JR. How early should blood pressure control be achieved for optimal cardiovascular outcomes? J Hum Hypertens 2011 Apr;25(4):211-7.
398. Whaley-Connell A, Purkayastha D, Yadao A, Sowers JR. Central pressure and biomarkerresponses to renin inhibition with dhyrocholorthiazide and ramipril in obese hypertensives: The ATTAIN study. Cardiorenal Med. 2011;1:53-66.
399. Habibi J, Demarco VG, Ma L, Pulakat L, Rainey WE, Whaley-Connell AT, Sowers JR. Mineralocorticoid receptor blockade improves diastolic function independent of blood pressure reduction in transgenic model of RAAS overexpression. Am J Physiol Heart Circ Physiol. 2011;300(4):H1484-91.
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400. ACCORD Study Group, Gerstein HC, Miller ME, Genuth S, Ismail-Beigi F, Buse JB, Goff DC Jr, Probstfield JL, Cushman WC, Ginsberg HN, Bigger JT, Grimm RH Jr, Byington RP, Rosenberg YD, Friedewald WT. Long-term effects of intensive glucose lowering on cardiovascular outcomes. N Engl J Med. 2011;364(9):818-28.
401. Giles TD, Oparil S, Ofili EO, Pitt B, Purkayastha D, Hilkert R, Samuel R, Sowers JR. The role of ambulatory blood pressure monitoring compared with clinic and home blood pressure measures in evaluating moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy. Blood Press Monit. 2011;16(2):87-95.
402. Hayden MR, Sowers JR. Childhood-adolescent obesity in the cardioreanl syndrome: lessons from animal models. Cardiorenal Med. 2011;2:75-86.
403. Ofili EO, Oparil S, Giles T, Pitt B, Purkayastha D, Hilkert R, Samuel R, Sowers JR. Moderate versus intensive treatment of hypertension using amlodipine/valsartan and with the addition of hydrochlorothiazide for patients uncontrolled on angiotensin receptor blocker monotherapy: results in racial/ethnic subgroups. J Am Soc Hypertens. 2011 Jul-Aug;5(4):249-58.
404. Manrique C, Lastra G, Habibi J, Pulakat L, Schneider R, Durante W, Tilmon R, Rehmer J, Hayden MR, Ferrario CM, Whaley-Connell A, Sowers JR. Nebivolol improves insulin sensitivity in the TGR(Ren2)27 rat. Metabolism. 2011 Dec;60(12):1757-66.
405. Zhang H, Wang Y, Zhang J, Potter BJ, Sowers JR, Zhang C. Bariatric surgery reduces visceral adipose inflammation and improves endothelial function in type 2 diabetic mice. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):2063-9.
406. Hayden MR, Sowers KM, Pulakat L, Joginpally T, Krueger B, Whaley-Connell A, Sowers JR. Possible mechanisms of local tissue renin-angiotensin system activation in the cardiorenal metabolic syndrome and type 2 diabetes mellitus. Cardiorenal Med. 2011;1(3):193-210.
407. Whaley-Connell A, Habibi J, Panfili Z, Hayden MR, Bagree S, Nistala R, Hyder S, Krueger B, Demarco V, Pulakat L, Ferrario CM, Parrish A, Sowers JR. Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-Cadherin. Am J Nephrol. 2011;34(2):115-25.
408. McFarlane SI, McCullough PA, Sowers JR, Soe K, Chen SC, Li S, Vassalotti JA, Stevens LA, Salifu MO, Kurella Tamura M, Bomback AS, Norris KC, Collins AJ, Bakris GL, Whaley-Connell AT; KEEP Steering Committee. Comparison of the CKD epidemiology collaboration (CKD-EPI) and modification of diet in renal disease (MDRD) study equations: prevalence of and risk factors for diabetes mellitus in CKD in the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis. 2011;57(3 Suppl 2):S24-31.
409. Johnson MS, Demarco VG, Heesch CM, Whaley-Connell AT, Schneider RI, Rehmer NT, Tilmon RD, Ferrario CM, Sowers JR. Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat. Am J Physiol Heart Circ Physiol. 2011;301(4):H1540-50.
410. Kurukulasuriya LR, Stas S, Lastra G, Manrique C, Sowers JR. Hypertension in obesity. Med Clin North Am. 2011 Sep;95(5):903-17. Review.
411. Raij L, Egan BM, Zappe DH, Purkayastha D, Samuel R, Sowers JR. Office and ambulatory blood pressure-lowering effects of combination valsartan/
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412. hydrochlorothiazide vs hydrochlorothiazide-based therapy in obese, hypertensive patients. J Clin Hypertens (Greenwich). 2011;13(10):731-8.
413. Whaley-Connell A, Sowers JR. Indices of obesity and cardiometabolic risk. Hypertension. 2011;58(6):991-3
414. Hayden MR, Sowers KM, Pulakat L, Joginpally T, Krueger B, Whaley-Connell A, Sowers JR: Possible mechanisms of local tissue renin-angiotensin system activation in the cardiorenal metabolic syndrome and type 2 diabetes mellitus. Cardiorenal Med. 2011;1(3):193-210.
415. Nistala R, Hayden MR, Demarco VG, Henriksen EJ, Lackland DT, Sowers JR: Prenatal programming and epigenetics in the genesis of the cardiorenal syndrome. Cardiorenal Med. 2011;1(4):243-254
417. Whaley-Connell A, Sowers JR: Aldosterone and risk for insulin resistance. Hypertension. 2011;58(6):998-1000.
418. Pulakat L, Demarco VG, Whaley-Connell A, Sowers JR: The impact of overnutrition on insulin metabolic signaling in the heart and the kidney. Cardiorenal Med. 2011;1(2):102-112
419. Saab G, Whaley-Connell A, Bombeck A, Kurella Tamura M, Li S, Chen SC, McFarlane SI, Sowers JR, Norris K, Bakris GL, McCullough PA; for the Kidney Early Evaluation Program Investigators: The association between parathyroid hormone levels and the cardiorenal metabolic syndrome in non-diabetic chronic kidney disease. Cardiorenal Med. 2011;1(2):123-130.
420. Sowers JR: The heart and the kidneys: partners in disease? Cardiorenal Med. 2011;1(1):1-2.
421. Sowers JR, Whaley-Connell A, Hayden MR: The role of overweight and obesity in the cardiorenal syndrome. Cardiorenal Med. 2011;1(1):5-12.
422. Whaley-Connell A, Pulakat L, Demarco VG, Hayden MR, Habibi J, Henriksen EJ, Sowers JR: Overnutrition and the cardiorenal syndrome: use of a rodent model to examine mechanisms. Cardiorenal Med. 2011;1(1):23-30.
423. Whaley-Connell A, Bomback AS, McFarlane SI, Li S, Roberts T, Chen SC, Collins AJ, Norris K, Bakris GL, Sowers JR, McCullough PA; on behalf of the Kidney Early Evaluation Program Investigators: Diabetic cardiovascular disease predicts chronic kidney disease awareness in the kidney early evaluation program. Cardiorenal Med. 2011;1(1):45-52.
424. Whaley-Connell A, Purkayastha D, Yadao A, Sowers JR: Central pressure and biomarker responses to renin inhibition with hydrochlorothiazide and ramipril in obese hypertensives: the ATTAIN study. Cardiorenal Med. 2011;1(1):53-66.
425. Hayden MR, Sowers JR. Childhood-Adolescent obesity in the cardiorenal syndrome: lessons from animal models. Cardiorenal Med. 2011;1(2):75-86.
426. Pulakat L, Aroor AR, Gul R, Sowers JR. Cardiac insulin resistance and microRNA modulators. Exp Diabetes Res. 2012;2012:654904.
dependent proximal tubule injury is mediated by a redox-sensitive mTOR/S6K1 pathway. Am J Nephrol. 2012;35(1):90-100.
428. Kim JA, Jang HJ, Martinez-Lemus LA, Sowers JR. Activation of mTOR/p70S6 Kinase by ANG II Inhibits Insulin Stimulated Endothelial Nitric Oxide Synthase and Vasodilation. Am J Physiol Endocrinol Metab. 2012;302(2):E201-8.
429. Sowers JR: Role of TRIB3 in diabetic and overnutrition-induced atherosclerosis. Diabetes. 2012;61(2):265-6.
430. Shababi M, Habibi J, Ma L, Glascock J, Sowers JR, Lorson CL: Partial restoration of cardio-vascular defects in rescued severe model of spinal muscular atrophy. J Mol Cell Cardiol. 2012 May;52(5):1074-82.
431. Sofue T, Kiyomoto H, Kobori H, Urushihara M, Nishijima Y, Kaifu K, Hara T, Matsumoto S, Ichimura A, Ohsaki H, Hitomi H, Kawachi H, Hayden MR, Whaley-Connell A, Sowers JR, Ito S, Kohno M, Nishiyama A. Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats. Am J Hypertens. 2012 May;25(5):604-11.
432. Nistala R, Sowers JR, Whaley-Connell A. Over-nutrition contributes to tubulointerstitial fibrosis by targeting nutrient-sensing kinases: Role for the mTOR/S6K pathway. Cell Cycle. 2012;11(5).
433. Demarco VG, Johnson MS, Ma L, Pulakat L, Mugerfeld I, Hayden MR, Garro M, Knight WC, Britton SL, Koch LG, Sowers JR. Overweight female rats selectively bred for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction. Am J Physiol Heart Circ Physiol. 012;302(8):H1667-82.
434. Whaley-Connell A, Sowers JR. The kaliuretic impact of cicletanine compared to hydrochlorothiazide. J Hypertens. 2012;30(4):691-2.
435. Ma L, Gul R, Habibi J, Yang M, Pulakat L, Whaley-Connell AT, Ferrario CM, Sowers JR. Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the transgenic (MRen2) rat. Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2341-51.
436. Mandavia CH, Pulakat L, Demarco V, Sowers JR. Over-nutrition and metabolic cardiomyopathy. Metabolism. 2012 Sep;61(9):1205-10.
437. Whaley-Connell A, Habibi J, Nistala R, Hayden MR, Pulakat L, Sinak C, Locher B, Ferrario CM, Sowers JR. Combination of direct renin inhibition with angiotensin type 1 receptor blockade improves aldosterone but does not improve kidney injury in the transgenic Ren2 rat. Regul Pept. 2012;176(1-3):36-44.
438. Siyam F, Abdullah O, Gardner M, Brietzke S, Sowers J. A case of carcinoid tumor-associated hypercalcemia. Cardiorenal Med. 2012;2(1):52-56.
439. Hayden MR, Habibi J, Joginpally T, Karuparthi PR, Sowers JR. Ultrastructure study of transgenic Ren2 rat aorta - part 1: endothelium and intima. Cardiorenal Med. 2012;2(1):66-82.
440. Whaley-Connell A, Sowers JR. Oxidative stress in the cardiorenal metabolic syndrome. Curr Hypertens Rep. 2012;14(4):360-5.
441. Whaley-Connell A, Sowers JR. Initial choice of antihypertensive on long-term cardiovascular outcomes in CKD. Clin J Am Soc Nephrol. 2012;7(6):884-6
442. Aroor AR, Mandavia C, Ren J, Sowers JR, Pulakat L. Mitochondria and oxidative stress in the cardiorenal metabolic syndrome. Cardiorenal Med. 2012;2(2):87-109.
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443. Deedwania PC, Zappe DH, Egan BM, Purkayastha D, Samuel R, Sowers JR. Does response of RAS blockade on serum K+ levels influence its glycemic-mitigating response when combined with hydrochlorothiazide? J Clin Hypertens (Greenwich). 2012 Jul;14(7):415-21.
444. Zhang Y, Sowers JR, Ren J. Pathophysiological insights into cardiovascular health in metabolic syndrome. Exp Diabetes Res. 2012;2012:320534.
445. Garcia-Vargas L, Addison SS, Nistala R, Kurukulasuriya D, Sowers JR. Gestational diabetes and the offspring: implications in the development of the cardiorenal metabolic syndrome in offspring. Cardiorenal Med. 2012;2(2):134-142.
446. Forte V, Pandey A, Abdelmessih R, Forte G, Whaley-Connell A, Sowers JR, McFarlane SI. Obesity, Diabetes, the cardiorenal syndrome, and risk for cancer. Cardiorenal Med. 2012;2(2):143-162.
447. Varagic J, Ahmad S, Voncannon JL, Moniwa N, Simington SW Jr, Brosnihan BK, Gallagher PE, Habibi J, Sowers JR, Ferrario CM. Nebivolol reduces cardiac angiotensin II, associated oxidative stress and fibrosis but not arterial pressure in salt-loaded spontaneously hypertensive rats. J Hypertens. 2012;30(9):1766-1774.
448. Muniyappa R, Sowers JR. Endothelial insulin and IGF-1 receptors: when yes means NO. Diabetes. 2012;61(9):2225-2227.
449. Manrique C, Lastra G, Habibi J, Mugerfeld I, Garro M, Sowers JR. Loss of estrogen receptor α signaling leads to insulin resistance and obesity in young and adult female mice. Cardiorenal Med. 2012;2(3):200-210.
450. Gul R, Demarco VG, Sowers JR, Whaley-Connell A, Pulakat L. Regulation of overnutrition-induced cardiac inflammatory mechanisms. Cardiorenal Med. 2012;2(3):225-233.
451. Aroor AR, Mandavia CH, Sowers JR. Insulin resistance and heart failure: molecular mechanisms. Heart Fail Clin. 2012;8(4):609-17.
452. Demarco VG, Ford DA, Henriksen EJ, Aroor AR, Johnson MS, Habibi J, Ma L, Yang M, Albert CJ, Lally JW, Ford CA, Prasannarong M, Hayden MR, Whaley-Connell AT, Sowers JR. Obesity-related alterations in cardiac lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db mice. Endocrinology. 2013;154(1):159-171.
453. Mandavia CH, Aroor AR, Demarco VG, Sowers JR. Molecular and metabolic mechanisms of cardiac dysfunction in diabetes. Life Sci. 2013;92(11):601-608.
454. Nistala R, Sowers JR. Hypertension: synergy of antihypertensives in elderly patients with CKD. Nat Rev Nephrol. 2013;9:13-15.
455. Muniyappa R, Sowers JR. Role of insulin resistance in endothelial dysfunction. Rev Endocr Metab Disord. 2013;14(1):5-12.
456. Jindal A, Whaley-Connell A, Brietzke S, Sowers JR. Therapy of obese patients with cardiovascular disease. Curr Opin Pharmacol. 2013;13(2):200-4.
457. Bakris GL, Oparil S, Purkayastha D, Yadao AM, Alessi T, Sowers JR. Randomized study of antihypertensive efficacy and safety of combination aliskiren/valsartan vs valsartan monotherapy in hypertensive participants with type 2 diabetes mellitus. J Clin Hypertens (Greenwich). 2013;15(2):92-100
458. Bender SB, McGraw AP, Jaffe IZ, Sowers JR. Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease? Diabetes. 2013;62(2):313-9.
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459. Whaley-Connell A, Habibi J, Rehmer N, Ardhanari S, Hayden MR, Pulakat L, Krueger C, Ferrario CM, DeMarco VG, Sowers JR. Renin inhibition and AT(1)R blockade improve metabolic signaling, oxidant stress and myocardial tissue remodeling. Metabolism. 2013;62(6):861-72.
460. Jindal A, Brietzke S, Sowers JR. Obesity and the cardiorenal metabolic syndrome: therapeutic modalities and their efficacy in improving cardiovascular and renal risk factors. Cardiorenal Med. 2012;2(4):314-327.
461. Mandavia C, Sowers JR. Phosphoprotein Phosphatase PP2A regulation of insulin receptor substrate 1 and insulin metabolic signaling. Cardiorenal Med. 2012;2(4):308-313.
462. Gul R, Ramdas M, Mandavia CH, Sowers JR, Pulakat L. RAS-Mediated Adaptive Mechanisms in Cardiovascular Tissues: Confounding Factors of RAS Blockade Therapy and Alternative Approaches. Cardiorenal Med. 2012;2(4):268-280.
463. Nistala R, Andresen BT, Pulakat L, Meuth A, Sinak C, Mandavia C, Thekkumkara T, Speth RC, Whaley-Connell A, Sowers JR. Angiotensin type 1 receptor resistance to blockade in the opossum proximal tubule cell due to variations in the binding pocket. Am J Physiol Renal Physiol. 2013;304(8):F1105-13.
464. Whaley-Connell A, Sowers JR. Metabolic impact of adding a thiazide diuretic to captopril. Hypertension. 2013;61(4):765-6.
465. Sowers JR. Diabetes mellitus and vascular disease. Hypertension. 2013;61(5):943-7.
466. Jindal A, Whaley-Connell A, Sowers JR. Obesity and heart failure as a mediator of the cerebrorenal interaction. Contrib Nephrol. 2013;179:15-23.
467. Aroor AR, Sowers JR, Bender SB, Nistala R, Garro M, Mugerfeld I, Hayden MR, Johnson MS, Salam M, Whaley-Connell A, Demarco VG. Dipeptidylpeptidase inhibition is associated with improvement in blood pressure and diastolic function in insulin-resistant male Zucker obese rats. Endocrinology. 2013;154(7):2501-13.
468. Jindal A, Whaley-Connell A, Sowers JR. Type 2 diabetes in older people; the importance of blood pressure control. Curr Cardiovasc Risk Rep. 2013;7(3):233-237.
469. Manrique C, DeMarco VG, Aroor AR, Mugerfeld I, Garro M, Habibi J, Hayden MR, Sowers JR. Obesity and insulin resistance induce early development of diastolic dysfunction in young female mice fed a Western diet. Endocrinology. 2013;154(10):3632-42.
470. Lastra G, Santos FR, Hooshmand P, Hooshmand P, Mugerfeld I, Aroor AR, Demarco VG, Sowers JR, Henriksen EJ. The Novel Angiotensin II Receptor Blocker Azilsartan Medoxomil Ameliorates Insulin Resistance Induced by Chronic Angiotensin II Treatment in Rat Skeletal Muscle. Cardiorenal Med. 2013;3(2):154-164.
471. Aroor AR, McKarns S, Demarco VG, Jia G, Sowers JR. Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance. Metabolism. 2013;62(11):1543-52.
472. Aroor A, McKarns S, Nistala R, Demarco V, Gardner M, Garcia-Touza M, Whaley-Connell A, Sowers JR. DPP-4 Inhibitors as Therapeutic Modulators of Immune Cell Function and Associated Cardiovascular and Renal Insulin Resistance in Obesity and Diabetes. Cardiorenal Med. 2013;3(1):48-56.
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473. Whaley-Connell AT, Habibi J, Aroor A, Ma L, Hayden MR, Ferrario CM, Demarco VG, Sowers JR. Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats. Metabolism. 2013;62(12):1761-71.
474. Aroor AR, Demarco VG, Jia G, Sun Z, Nistala R, Meininger GA, Sowers JR. The Role of Tissue Renin-Angiotensin-Aldosterone System in the Development of Endothelial Dysfunction and Arterial Stiffness. Front Endocrinol (Lausanne). 2013;4:161.
475. Jindal A, Garcia-Touza M, Jindal N, Whaley-Connell A, Sowers JR. Diabetic kidney disease and the cardiorenal syndrome: old disease, new perspectives. Endocrinol Metab Clin North Am. 2013;42(4):789-808.
476. Linden MA, Fletcher JA, Morris EM, Meers GM, Kearney ML, Crissey JM, Laughlin MH, Booth FW, Sowers JR, Ibdah JA, Thyfault JP, Rector RS. Combining Metformin and Aerobic Exercise Training in the Treatment of Type 2 Diabetes and NAFLD in OLETF Rats. Am J Physiol Endocrinol Metab. 2013 Dec 10. [Epub ahead of print]
477. Jia G, Sowers JR. New Thoughts in an Old Player: Role of Nitrite in the Treatment of Ischemic Revascularization. Diabetes. 2014;63(1):39-41.
478. Whaley-Connell A, Sowers JR. Implications for Glucose Measures in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study. Diabetes. 2014;63:45–47.
479. Lastra G, Syed S, Kurukulasuriya LR, Manrique C, Sowers JR. Type 2 diabetes mellitus and hypertension: an update. Endocrinol Metab Clin North Am. 2014;43(1):103-22.
480. Manrique C, Lastra G, Sowers JR. New insights into insulin action and resistance in the vasculature. Ann N Y Acad Sci. 2014;1311:138-50.
481. Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, Vella A. Time to look back and to look forward. Diabetes. 2014;63(4):1169-70.
482. Muniyappa R, Sowers JR. Glycogen synthase kinase-3β and cathepsin B in diabetic endothelial progenitor cell dysfunction: an old player finds a new partner. Diabetes. 2014;63(4):1194-7.
483. Grais IM, Sowers JR. Thyroid and the Heart. Am J Med. 2014 Mar 21.484. Nistala R, Habibi J, Lastra G, Manrique C, Aroor AR, Hayden MR, Garro M, Meuth
A, Johnson M, Whaley-Connell A, Sowers JR. Prevention of Obesity-Induced Renal Injury in Male Mice by DPP4 Inhibition. Endocrinology. 2014;155(6):2266-76. PMCID: PMC4020930
485. DeMarco VG, Aroor AR, Sowers JR. The pathophysiology of hypertension in patients with obesity. Nat Rev Endocrinol. 2014;10(6):364-76. doi:10.1038/nrendo.2014.44
486. Jia G, Aroor AR, Whaley-Connell AT, Sowers JR. Fructose and uric acid: is there a role in endothelial function? Curr Hypertens Rep. 2014;16(6):434. PMCID: PMC4084511
487. Habibi J, Hayden MR, Ferrario CM, Sowers JR, Whaley-Connell AT. Salt Loading Promotes Kidney Injury via Fibrosis in Young Female Ren2 Rats. Cardiorenal Med. 2014;4(1):43-52. PMCID: PMC4025048
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488. Jia G, Aroor AR, Sowers JR. Arterial Stiffness: A Nexus between Cardiac and Renal Disease. Cardiorenal Med. 2014;4(1):60-71. PMCID: PMC4024508
489. Yousef I, Siyam F, Layfield L, Freter C, Sowers JR. Cervical neuroendocrine tumor in a young female with Lynch Syndrome. Neuro Endocrinol Lett. 2014;35(2):89-94. PMID: 24878972
490. Aroor AR, Sowers JR, Jia G, DeMarco VG. Pleiotropic Effects of the Dipeptidylpeptidase-4 Inhibitors on the Cardiovascular System. Am J Physiol Heart Circ Physiol. 2014 Jun 13. pii: ajpheart.00209.2014. [Epub ahead of print]. PMCID: PMC4137125
491. Bostick B, Habibi J, Ma L, Aroor A, Rehmer N, Hayden MR, Sowers JR. Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a Mouse model of Western diet induced obesity. Metabolism. 2014 Aug;63(8):1000-11. PMCID: PMC4128682
492. Linden MA, Fletcher JA, Morris EM, Meers GM, Laughlin MH, Booth FW, Sowers JR, Ibdah JA, Thyfault JP, Rector RS. Treating NAFLD in OLETF Rats with Vigorous-Intensity Interval Exercise Training. Med Sci Sports Exerc. 2014 Jun 30. [Epub ahead of print]. PMID: 24983336
493. Jia G, Sowers JR. Autophagy: A housekeeper in cardiorenal metabolic health and disease. Biochim Biophys Acta. 2014 Jun 28. pii: S0925-4439(14)00202-6. doi: 10.1016/j.bbadis.2014.06.025. [Epub ahead of print] Review. PMID: 24984281
494. Nistala R, Habibi J, Aroor A, Sowers JR, Hayden MR, Meuth A, Knight W, Hancock T, Klein T, DeMarco VG, Whaley-Connell A. DPP4 Inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat. Obesity (Silver Spring). 2014 Oct;22(10):2172-9. PMCID:PMC4180797
495. Jia G, Aroor AR, Sowers JR. Estrogen and mitochondria function in cardiorenal metabolic syndrome. Prog Mol Biol Transl Sci. 2014;127:229-49. PMID: 25149220
496. Whaley-Connell A, Sowers JR. Basic science: Pathophysiology: the cardiorenal metabolic syndrome. J Am Soc Hypertens. 2014 Aug;8(8):604-6. PMCID: PMC4170524
497. Jia G, Sowers JR. Endothelial dysfunction potentially interacts with impaired glucose metabolism to increase cardiovascular risk. Hypertension. 2014 64(6):1192-3. PMID: 25225204
498. Ren J, Sowers JR. Application of a novel curcumin analog in the management of diabetic cardiomyopathy. Diabetes. 2014 Oct;63(10):3166-8. PMCID: PMC4171654
499. Jia G, Aroor AR, Martinez-Lemus LA, Sowers JR. Invited Review: Over-nutrition, mTOR Signaling and Cardiovascular Diseases. Am J Physiol Regul Integr Comp Physiol. 2014 307(10):R1198-206. PMID: 25253086
500. Jia G, Sowers JR. Interaction of Islet α-Cell and β-Cell in the Regulation of Glucose Homeostasis in HI/HA Syndrome Patients With the GDHH454Y Mutation. Diabetes. 2014;63(12):4008-10. PMID: 25414017
501. Jia G, Habibi J, Bostick BP, Ma L, DeMarco VG, Aroor AR, Hayden MR, Whaley-Connell AT, Sowers JR. Uric Acid Promotes Left Ventricular Diastolic Dysfunction in Mice Fed a Western Diet. Hypertension. 2015;65(3):531-9 PMCID: PMC4370431
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502. Bender SB, Jia G, Sowers JR. Mineralocorticoid receptors: an appealing target to treat coronary microvascular dysfunction in diabetes. Diabetes. 2015;64(1):3-5. PMCID: PMC4274807
503. Jia G, Aroor AR, Martinez-Lemus LA, Sowers JR. Mitochondrial functional impairment in response to environmental toxins in the cardiorenal metabolic syndrome. Arch Toxicol. 2015;89(2):147-53. PMCID:PMC4312177
504. Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS. Dipeptidyl peptidase-4 inhibition ameliorates Western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes. 2015;64(6):1988-2001. PMCID:PMC4439570
505. de Zeeuw D, Anzalone DA, Cain VA, Cressman MD, Heerspink HJ, Molitoris BA, Monyak JT, Parving HH, Remuzzi G, Sowers JR, Vidt DG. Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial. Lancet Diabetes Endocrinol. 2015;3(3):181-90. PMID: 25660356
506. Jia G, Sowers JR. Autoantibodies of β-adrenergic and M2 cholinergic receptors: atrial fibrillation in hyperthyroidism. Endocrine. 2015;49(2):301-3. PMCID: PMC4447568
507. Grais IM, Sowers JR. The reply. Am J Med. 2015;128(3):e11. PMID: 25707886508. Bender SB, DeMarco VG, Padilla J, Jenkins NT, Habibi J, Garro M, Pulakat L,
509. Manrique C, Sowers JR. Insulin resistance and skeletal muscle vasculature: significance, assessment and therapeutic modulators. Cardiorenal Med. 2014;4(3-4):244-56. PMCID: PMC4299173
510. Bostick B, Habibi J, DeMarco VG, Jia G, Domeier TL, Lambert MD, Aroor AR, Nistala R, Bender SB, Garro M, Hayden MR, Ma L, Manrique C, Sowers JR. Mineralocorticoid receptor blockade prevents Western diet-induced diastolic dysfunction in female mice. Am J Physiol Heart Circ Physiol. 2015;308(9):H1126-35. PMID: 25747754
511. Chen S, Meng F, Chen Z, Tomlinson BN, Wesley JM, Sun GY, Whaley-Connell AT, Sowers JR, Cui J, Gu Z. Two-dimensional zymography differentiates gelatinase isoforms in stimulated microglial cells and in brain tissues of acute brain injuries. PLoS One. 2015;10(4):e0123852. PMCID:PMC4393235
512. DeMarco VG, Sowers JR. Ghrelin: a new incretin enhancer therapy? Diabetes. 2015;64(5):1500-2. PMCID: PMC4407859
513. Padilla J, Vieira-Potter VJ, Jia G, Sowers JR. Role of perivascular adipose tissue on vascular reactive oxygen species in type 2 diabetes: a give-and-take relationship. Diabetes. 2015;64(6):1904-6. PMCID: PMC4439571
514. DeMarco VG, Habibi J, Jia G, Aroor AR, Ramirez-Perez FI, Martinez-Lemus LA, Bender SB, Garro M, Hayden MR, Sun Z, Meininger GA, Manrique C, Whaley-Connell A, Sowers JR. Low-Dose Mineralocorticoid Receptor Blockade Prevents Western Diet-Induced Arterial Stiffening in Female Mice. Hypertension. 2015;66(1):99-107. PMCID:PMC4465849
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515. Bender SB, Castorena-Gonzalez JA, Garro M, Reyes-Aldasoro CC, Sowers JR, DeMarco VG, Martinez-Lemus LA. Regional variation in arterial stiffening and dysfunction in western diet-induced obesity. Am J Physiol Heart Circ Physiol. 2015 Jun 19:ajpheart.00155.2015. doi: 10.1152/ajpheart.00155.2015. [Epub ahead of print] PMID:26092984
516. Jia G, Martinez-Lemus LA, Sowers JR. Interaction of Adipogenesis and Angiogenesis in Dietary-Induced Obesity. Diabetes. 2015;64(7):2326-8. PMCID:PMC4477362
517. Lastra G, Manrique C, Jia G, Sowers JR. The VASP Road to NAFLD: A Macrophage Detour. Diabetes. 2015;64(8):2711-3. PMID: 26207036
REV IEW ART IC LE S 1. Sowers DK and JR Sowers. Pituitary emergencies. Critical Care Quarterly 3:45-
54, 1980.2. Sowers JR. Dietary care of the insulin-dependent diabetic patient. JAMA
245(17):1771, 1981.3. Trujillo A and JR Sowers. Diabetes, diet control, and weight loss. JAMA 249:1509,
1983.4. Sowers JR. Dopamine regulation of renin and aldosterone secretion: A Review.
J of Hypertension 2(suppl1), 67-73, 1984.5. Sowers JR. Managing geriatric hypertension: A brief review. Geriatrics 40(3), 63-
66, 1985.6. Sowers, JR and SM Gualdoni. Systolic Hypertension: Its significance and
management in elderly patients. Consultant, December: 44-61, 1985.7. Bloch MH and JR Sowers. Vitiligo and polyglandular autoimmune endocrinopathy.
Cutis, November: 417- 419, 1985.8. Sowers JR and HR Lippman.Cushing's syndrome due to ectopic ACTH
production: Cutaneous manifestations. Cutis, October: 351-354, 1985.9. Mulligan TM and JR Sowers. Hyperpigmentation, Vitiligo, and Addison's Disease.
Cutis. October: 317-319, 1985.10. Gualdoni SM and JR Sowers: Dietary sodium and calcium in hypertension.
Nutrition News, 49(2), April 1986.11. Sowers JR and PK Mohanty. Comparison of Calcium-Entry Blockers and
Diuretics in the Treatment of Hypertensive Patients. Circulation. 75(Suppl 5):V-170-V-173, 1987.
12. Sowers JR Hypertension in the elderly. Am J Med 82(suppl 1B):1-8, 1987.13. Imam K, JR Sowers. Causes of characteristics of hypertension in the geriatric
patient. Geriatric Medicine 6(11):19-32, 1987.14. Felicetta J and JR Sowers. Systemic hypertension in diabetes mellitus. Am J
Cardiol 61:34H-40H, 1988.15. Zemel MB and JR Sowers. Salt sensitivity and hypertension in the elderly. Am J
Cardiol 61:7H-12H, 1988.
44
16. Sowers JR The metabolic effects of diuretic therapy in hypertension. Arch Intern Med. 9(3):130-145. 1988.
17. Imam K, JR Sowers. Obesity and hypertension: A review. Henry Ford Hosp Med J 36(2):82-87, 1988.
18. Piepho R and JR Sowers. Antihypertensive therapy in the geriatric patient: A review of the role of calcium channel blockers. J Clin Pharmacol 29:193-200, 1989.
19. Imam K, M Maddens, PK Mohanty, JV Felicetta, and JR Sowers. ANP attenuates reflex sympathetic responses to lower body negative pressure. Am J Med Sci 298:1-7, 1989.
20. Sowers JR. Dietary calcium effects in salt-sensitive hypertension. J Clin Nutr 8(4):158-163, 1989.
21. Sowers JR, M Zemel, P Standley, P Zemel. Calcium and hypertension. J Lab Clin Med 114:338-348, 1989.
22. Sowers JR, P Zemel, M Zemel, SE Kasim, S Khoury. Hypertension and Atherosclerosis Calcium antagonist as antiatherogenic agents. J Vasc Med Biol 2:1-6, 1990.
23. Sowers JR, MB Zemel. Clinical implications of hypertension in the diabetic patient. A Review. Am J Hyperten 3:415-424, 1990.
24. Sowers JR. Relationship between hypertension and subtle and overt abnormalities of carbohydrate metabolism. J Am Soc Nephrol 1:S39-S47, 1990.
25. Sowers JR. At the Cutting Edge: Insulin resistance and hypertension. Mol Cel Endo 74:C87-C89, 1990.
26. Zemel PC, Sowers JR. Relation between lipids and atherosclerosis: epidemiologic evidence and clinical implications. Am J Cardiol 66:7I-12I, 1990.
27. Sowers JR. Calcium channel blockers and atherosclerosis. Am J Kidney Dis 4(Suppl 1):3-9, 1990.
28. Zemel MB, Sowers JR. Dietary calcium, sodium, and hypertension in blacks and the elderly. NutritionalFactors in Hypertension pp 131-144, 1990.
29. Sowers JR, Khoury S, Standley P, Zemel P, Zemel M. Mechanisms of Hypertension in Diabetes. Am J Hyperten Feb. 4:177-183, 1991.
30. Flack JM, Sowers JR. Epidemiologic and clinical aspects of insulin resistance and hyperinsulinemia. Am J Med 91(suppl 1A):11S-21S, 1991.
32. Sowers JR, Khoury S, Imam K, Byyny R. Therapeutic approach to hypertension in the elderly. PrimaryCare 18:593-605, 1991.
33. Sowers JR. Diabetes and Hypertension: A Review. Primary Care 18:509-524, 1991.
34. Sowers JR. Calcium antagonists to treat atherosclerosis. Atherosclerosis and hypertension:clues to effective prevention and treatment. Cleveland Clinic Journal of Medicine 58(6):461, 1991.
45
35. Epstein M, Sowers JR. Diabetes Mellitus and Hypertension. Hypertension 19:403-418, 1992.
36. Sowers JR. Insulin resistance, hyperinsulinemia, dyslipidemia, hypertension and accelerated atherosclerosis. J Clin Pharm 32:529-535, 1992.
37. Sowers JR. Antiatherosclerotic effects of calcium channel blockers. Postgraduate Medicine 92(2):265-268, 1992.
38. Sowers, JR: Common Pathology II: The involvement of Glucose and Insulin Metabolism in the Pathogenesis of Hypertension and Atherosclerosis. Comorbidity 4:3-9, 1992.
42. Edelson GW, Sowers JR: Insulin Resistance in Hypertension: a focused review. Am J Med Sci 306(5):345-347, 1993.
43. Edelson GW, Sowers JR: Treatment of hypertension in selected patient groups: an emphasis on diabetes mellitus and hypertension. The Endocrinologist 1994;4:205-211.
44. Edelson G W, Sowers JR. Managing hypertension in patients with diabetes mellitus. Contemp Int Med1995; 7(3):56-63.
45. Walsh MF, Dominguez LJ, Sowers JR. Diabetes, hypertension and vascular disease: etiology, evaluation and treatment. Cardiol Rev 1995; 3:4,1 75-183.
46. Jacober SJ, Sowers JR. Questions and answers: Exercise and Hypertension. JAMA 1995;273(24):1965.
47. Sowers JR. The physiology of weight and salt load on hypertension and implications for management in the African-American population. J Natl Med Assoc 1995;8 7(8):610-611.
48. Walsh MF, Dominguez LJ, Sowers JR. Metabolic abnormalities in cardiac ischemia. Cardiology Clinics 1995;13(4):529-538.
49. Sowers JR, Epstein M. Diabetes mellitus and hypertension, emerging therapeutic perspectives. Cardiovascular Drug Reviews, 1995;13(2):149-210.
50. Sowers JR. Effects of ACE inhibitors and calcium channel blockers on insulin sensitivity and other components of the syndrome. Nephrol Dial Transplant 1995;]O(Suppl 9):52-55
51. Sowers JR, Basha B. Atherosclerosis: an update. Amer Heart J 1996, 6:1192-1202
52. Sowers JR, Farrow SL. Treatment of elderly hypertensive patients with diabetes, renal disease and coronary heart disease. Am J Geriatr Cardiol 1996;5:57-70.
53. Applegate WB, Sowers JR. Elevated systolic blood pressure: increased cardiovascular risk and rationale for treatment. Am J Med 1996;101(3A):3S-9S.
54. Hanes DS, Wier MR, Sowers JR. Gender considerations in hypertension pathophysiology and treatment. AmJ Med 1996;101(3A):10S-21S.
46
55. Bakris GL, Weir MR, Sowers JR. Therapeutic challenges in the obese diabetic patient with hypertension. Am J Med 1996;101(3A):33S-46S.
56. Alfonso LC, Edeslon G, Sowers JR. Metabolic abnormalities in hypertension. Current opinion in Nephrology and Hypertension 1997;6:219-223.
57. Sowers JR. Impact of lipid and ACE inhibitor therapy on cardiovascular disease and metabolic abnormalities in the diabetic and hypertensive patient. J Hum Hypertens 1997;11:9-16.
58. Sowers JR. Effects of calcium antagonists on insulin sensitivity and other metabolic parameters. Am J Cardiol 1997;79:24-28.
59. Bermann MA, Walsh MF, Sowers JR. Angiotensin-II biochemistry and physiology: update on angiotensin-II receptor blockers. Cardiovascular Drug Reviews. 1997;15:75-100.
60. Ali SS, Sowers JR. Update on the management of hypertension. Treatment of the elderly and diabetic hypertensives. Is the approach to management really different? Cardiovasc Res & Rep 1998;6:44-54.
61. Guzmán CB, Sowers JR. Cardiovascular disease in postmenopausal women. Cardiovasc Rev Rep 12:55-61, 1998.
62. Abu-Hamdan DK, Sowers JR. Diabetes, dyslipidemia, and renal disease in the elderly. CVR&R 1998, 2:60-64.
63. Sowers JR. Comorbidity of hypertension and diabetes: The fosinopril versus amlodipine cardiovascular events trial (FACET) Am J Cardiol 82:15R-19R, 1998.
64. Sowers JR, Lester M. Diabetes and cardiovascular disease. Diabetes Care 22(Suppl 3):C14-C20, 1999
65. Sowers KMR, Sowers JR. Obesity, hypertension, and vascular disease. Curr Hypertens Reports 1:140-144, 1999.
66. Sowers JR. Diabetes and hypertension: an update. Curr Opin Endocrinol Diabetes 1999, 6:245-250.
67. Kaseta JR, Skafar DF, Ram JL, Jacober SJ, Sowers JR. Cardiovascular disease in the diabetic woman. J Clin Endocrinol Metab 1999, 84:1835-1838.
68. Sowers JR. Hypertension in type II diabetes: Update on therapy. J Clin Hypertens 1999;1:41-47.
69. Guzmán CB, Sowers JR. Special considerations in the therapy of diabetic hypertension. Progr CardiovascDis 1999; 41(6):461-470.
70. Kaseta JR, Sowers JR. Diabetes mellitus and cardiovascular disease in the older woman. Clin Geriatrics 1999; 7:52-62.
71. Kirpichnikov D, Sowers JR. Effects of ACE inhibitor therapy on development of type 2 diabetes in hypertensive patients. Cardiol Rev 6:5-7, 2000.
72. Kirpichnikov D, Sowers JR. Diabetes mellitus and diabetes-associated vascular disease. Trends inEndocrinology & Metabolism 12(5):225-230, 2001.
73. Kassab E, McFarlane SI, Sowers JR. Vascular complications in diabetes and their prevention. Vascular Medicine 6:249-255, 2001. Review
74. Jacober SJ, Sowers JR. Management of diabetes in patients undergoing surgery. Practical Diabetology 20(4):7-14, 2001. Review
47
75. Sowers JR. Update on the cardiometabolic syndrome. Clin Cornerstone 4(2):17-23, 2001. Review
76. Sowers JR. Hypertension in type 2 diabetes: Update on therapy. CVR&R 23(1):41-46, 2002.
77. Sowers JR. Diabetic nephropathy and concomitant hypertension: a review of recent ADA recommendations. Am J Clin Proc 2002;3:27-33. Review
78. Kaur J, Singh P, Sowers JR. Diabetes and cardiovascular diseases. Am J Ther 2002;9(6):510-515. Review
79. Kirpichnikov D, Winer N, Sowers JR. The use of ACE inhibitors on diabetic patients without renal disease. Curr Diab Rep 2(1):21-25, 2002. Review
80. Kirpichnikov D, Sowers JR. Role of ACE inhibitors in treating hypertensive diabetic patients. Curr Diab Rep 2(3):251-257, 2002. Review
81. Bakris GL, Sowers JR. Microalbuminuria in diabetes: focus on cardiovascular and renal risk reduction. Curr Diab Rep 2(3):258-262, 2002. Review
82. Winer N, Sowers JR. Cardiovascular risk factors in diabetic patients with hypertension. Curr Diab Rep 2(3):263-266, 2002. Review
83. Sowers JR. Effects of statins on the vasculature: implications for aggressive lipid management in the cardiovascular metabolic syndrome. Am J Cardiol 2003;91(suppl):14B-22B. Review
84. McFarlane S, Kumar A, Sowers JR. Mechanisms by which angiotensin-converting enzyme inhibitors prevent diabetes and cardiovascular disease. Am J Cardiol 91(suppl):30H-37H, 2003. Review
85. Blendea MC, McFarlane SI, Isenovic ER, Gick G, Sowers JR. Heart disease in diabetic patients. Curr Diab Rep 3(3):223-229, 2003. Review
86. McFarlane SI, Kumar A, Sowers JR. Mechanisms by which angiotensin-converting enzyme inhibitors prevent diabetes and cardiovascular disease. Am J Cardiol 91(12A):30H-37H, 2003. Review
87. Frohlich ED, Sowers JR. Management of diabetic and hypertensive cardiovascular disease. Curr Hypertens Rep 5(4):309-315, 2003. Review
88. McFarlane SI, Farag A, Sowers J. Calcium antagonists in patients with type 2 diabetes and hypertension. Cardiovasc Drug Rev 21(2):105-18, 2003. Review
89. Castro JP, El-Atat FA, McFarlane SI, Aneja A, Sowers JR. Cardiometabolic syndrome: pathophysiology and treatment. Curr Hypertens Rep 5(5):393-401, 2003.Review
90. Kirpichnikov D, McFarlane SI, Sowers JR. Heart failure in diabetic patients: utility of beta-blockade. J CardFail 9(4):333-344, 2003. Review
91. Moser M, Sowers J, Giles T. Roundtable discussion: management of hypertension in diabetics. J Clin Hypertens 5(5):345-349, 2003. Review
92. Sowers JR. Obesity as a cardiovascular risk factor. Am J Med 115 Suppl 8A:37S-41S, 2003. Review
93. Sowers JR. Therapeutic lifestyle changes in the management of obesity. Endocr Pract 9 Suppl 2: 97-98, 2003. Review
94. El-Atat F, Aneja A, McFarlane S, Sowers J. Obesity and hypertension. Endocrinol Metab Clin North Am 32(4): 823-854, 2003.Review
48
95. Winer N, Sowers JR. Vascular compliance in diabetes. Curr Diab Rep 3(3):230-234, 2003.
96. Sowers JR. Recommendations for special populations: diabetes mellitus and the metabolic syndrome. Am J Hypertens 16(11 Suppl):41-45, 2003.
97. McFarlane SI, Winer N, Sowers JR. Role of the natriuretic peptide system in cardiorenal protection. Arch Intern Med 163(22):2696-2704, 2003.
98. Sowers JR. Stroke in patients with diabetes. J Clin Hypertens 6(2): 62-63, 2004.99. Sowers JR, Frohlich ED. Insulin and insulin resistance: impact on blood pressure
and Cardiovascular disease. Med Clin North Am 88(1): 63-82, 2004.100. Sowers JR. Treatment of Hypertension in Patients with Diabetes. Am J Hypertens
164: 1850-1857, 2004.101. Aneja A, El-Atat F, McFarlane S, Sowers JR. Hypertension and obesity. Recent
Prog Horm Res 59: 169-205, 2004. Review102. McFarlane SI, Muniyappa R, Shin JJ, Bahtiyar G, Sowers JR. Osteoporosis and
cardiovascular disease. Endocrine 23(1): 1-10, 2004.103. Sowers, James R. Estrogen-Inducible cytoskeletal linker protein ezrin
interaction with the low-density lipoprotein receptor. Endocrinology 145(7): 3074, 2004.
104. Whaley-Connell A, Sowers JR. Hypertension management in type 2 diabetes mellitus: recommendations of the Joint National Committee VII. Endocrinol Metab Clin North Am. 2005 Mar;34(1):63-75. Review.
105. Shin JJ, Rothman J, Farag A, McFarlane SI, Sowers JR. Role of oral anti-diabetic agents in modifying cardiovascular risk factors. Minverva Med 94(6):401-408, 2003. Review
106. McFarlane SI, Muniyappa R, Shin JJ, Bahtiyar G, Sowers JR. Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link? Endocrine 23(1): 1-10, 2004. Review
107. Winer N, Sowers JR. Epidemiology of diabetes. J Clin Pharmacol 44(4): 397-405, 2004. Review
108. El-Atat F, McFarlane SI, Sowers JR. Diabetes, hypertension, and cardiovascular derangements: pathophysiology and management. Curr Hypertens Rep 6(3): 215-223, 2004. Review
109. Capricchione A, Winer N, Sowers JR. Adrenocortical hypertension. Curr Hypertens Rep 6(3): 224-229, 2004. Review
110. El-Atat FA, McFarlane SI, Sowers JR, Bigger JT. Sudden cardiac death in patients with diabetes. Curr Hypertens Rep 4(3): 187-193, 2004. Review
111. Bahtiyar G, Shin JJ, Aytaman A, Sowers JR, McFarlane SI. Association of diabetes and hepatitis C infection: epidemiologic evidence and pathophysiologic insights. Curr Diab Rep 4(3): 194-198, 2004. Review
112. Stas SN, El-Atat FA, Sowers JR, Pathogenesis of hypertension in diabetes. Rev Endocr Metab Disord. 5(3):221-5, 2004. Review
113. Capricchione Angelo M, Winter Nathaniel, Sowers James R, Hypertension, Endocrine. Encyclopedia of Endocrine Diseases (2): 592-602, 2004. Review
49
114. Tan AS, Kuppuswamy S, Whaley-Connell AT, Kurukulasuriya LR, Sowers JR, Recommendations for Special Populations: The Treatment of Hypertension in Diabetes Mellitus. The Endocrinologist 2004:14(6):368-382. Review
115. Nobles-James C, James EA, Sowers JR, Prevention of cardiovascular complications of diabetes mellitus by aspirin. Cardiovasc Drug Rev. 2004:22(3):215-26. Review
116. El-Atat FA, Stas SN, McFarlane SI, Sowers JR, The Relationship between Hyperinsulinemia, Hypertension and Progressive Renal Disease. J Am Soc Nephrol. 2004 Nov;15(11):2816-27. Review
117. Sowers JR, Stump CS, Insights into the biology of diabetic vascular disease: What's new? Am J Hypertens. 2004 Nov;17(11 Suppl):S2-6. Review
118. Sowers JR, Diabetes in the elderly and in women: cardiovascular risks. Cardiol Clin. 2004 Nov;22(4):541-51. Review
119. Mugo MN, Sowers JR. Early and aggressive treatment of complex hypertension. J Clin Hypertens.7(1):8-10, 2005. Review
120. Aras R, Sowers JR, Arora R. The Proinflammatory and Hypercoagulable State of Diabetes Mellitus. Reviews of Cardiovascular Medicine. 6(X):1-15,2005. Review
121. McFarlane SI, Sica DA, Sowers JR. Stroke in Patients with Diabetes and Hypertension. J Clin Hypertens (Greenwich). 2005 May;7(5):286-92. Review
122. Hayden MR, Suresh CT, Kolb L, Sowers JR, Khanna R. Vascular ossification - calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis - calcific uremic arteriolopathy: the emerging role of sodium thiosulfate. Cardiovasc Diabetol. 4(1):4, 2005. Review
123. Mugo M, Sowers JR. Metabolic syndrome: implications of race and ethnicity. Ethn Dis.14(4):S2-26-31;2004. Review
124. Whaley-Connell A, Sowers JR. Hypertension management in type 2 diabetes mellitus: recommendations of the Joint National Committee VII. Endocrinol Metab Clin North Am. 2005;34(1):63-75. Review
125. Winer N, Folker A, Murphy JA, Hung E, Bard M, Perkelvald A, Sowers, JR, Bakris GL: Effect of Fixed- Dose ACE Inhibitor/CCB Combination Therapy vs ACE Inhibitor Monotherapy on Arterial Compliance in Hypertensive Patients With Type 2 Diabetes. Prev Cardiology 2005;8:87-92. Review
126. Dominguez LJ, Sowers JR. Metabolic syndrome therapy: prevention of vascular injury by antidiabetic agents. Curr Hypertens Rep. 2005;7(2):110-6. Review
127. Manrique C, Lastra G, Whaley-Connell A, Sowers JR. Hypertension and the Cardiometabolic Syndrome. J Clin Hypertens. 2005;7(8):471-476. Review
128. Mugo M, Govindarajan G, Kurukulasuriya R, Sowers JR, McFarlane SI. Hypertension in Pregrancy. Curr Hypertens Rep. 2005 Oct;7(5):348-54. Review
129. Lastra-Gonzalez G, Manrique CM, Govindarajan G, Whaley-Connell A, Sowers JR. Insights into the emerging cardiometabolic prevention and management of diabetes mellitus. Expert Opin Pharmacother. 2005;6(13):2209-21. Review
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130. Dominguez L, Sowers JR, Barbagallo M. The Importance of Tight Blood Pressure Control in Diabetic Hypertensive Patients. Rev Bras Hypertension. 2005; 12(1): 7-12. Review
131. Hayden MR, Sowers JR. Hypertension in Type 2 Diabetes Mellitus. Insulin. 2005 Oct;1(1):22-37. Review
132. Gill H, Mugo M, Whaley-Connell A, Stump C, Sowers JR.The key role of insulin resistance in the cardiometabolic syndrome. Am J Med Sci. 2005 Dec;330(6):290-4. Review
133. Manrique CM, Lastra G, Palmer J, Stump CS, Sowers JR. Hypertension-a treatable component of the cardiometabolic syndrome: challenges for the primary care physician. J Clin Hypertens (Greenwich). 2006 Jan;8(1 Suppl 1):12-20. Review
134. Govindarajan G, Whaley-Connell A, Mugo M, Stump C, Sowers JR. The cardiometabolic syndrome as a cardiovascular risk factor. Am J Med Sci. 2005 Dec;330(6):311-8. Review
135. McFarlane SI, Sower JR. Gender disparities in the control of cardiovascular risk factors in people with diabetes. J Clin Hypertens (Greenwich). 2005;7(7):383-5.
136. Capricchione A, Winer N, Sowers JR. Adrenocortical hypertension. Curr Urol Rep. 2006 Jan;7(1):73-9. Review
137. Stump CS, Hamilton MT, Sowers JR. Effect of Antihypertensive Agents on the Development of Type 2 Diabetes Mellitus. May Clin Proc. 2006;81(6):796-806. Review
138. Mugo M, Matta R, Kurukulasuriya R, Sowers JR. Association of Hepatitis C Virus Infection and Diabetes Mellitus. The Endocrinologist. 2006; 16(1):41-48. Review
139. Arora R, Sowers JR, Saunders E, Probstfield J, Lazar HL. Cardioprotective strategies to improve long-term outcomes following coronary artery bypass surgery. J Card Surg. 2006 Mar-Apr;21(2):198-204. Review.
140. Bechtold M, Palmer J, Valtos J, Iasiello C, Sowers J. Metabolic syndrome in the elderly. Curr Diab Rep.2006 Feb;6(1):64-71.
141. Khan KA, Govindarajan G, Whaley-Connell A, Sowers JR. Diabetic Hypertension. Heart Failure Clin. 2006; (2): 25-36.
142. Arora R, Sowers JR, Saunders E, Probstfield J, Lazar HL. Cardioprotective strategies to improve long-term outcomes following coronary artery bypass surgery. J Card Surg. 2006 Mar-Apr;21(2):198-204.
143. Lastra G, Manrique C, McFarlane SI, Sowers JR. Cardiometabolic Syndrome and Chronic Kidney Disease. Curr Diab Rep. 2006, 6:207-212.
144. McFarlane SI, Salifu MO, Makaryus J, Sowers JR. Anemia and Cardiovascular Disease in Diabetic Nephropathy. Curr Diab Rep. 2006, 6:213-218.
145. Stump CS, Sowers JR. Prevention of Type 2 Diabetes: Role of the Renin-Angiotensin-Aldosterone System and Antihyptensive Therapy. Adv Stud Med. 2006;6(5):231-239.
146. Kurukulasuriya LR, Govindarajan G, Sowers J. Stroke prevention in diabetes and obesity. Expert Rev Cardiovasc Ther. 2006 Jul;4(4):487-502.
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147. Stas S, Appesh L, Sowers J. Metabolic safety of antihypertensive drugs: myth versus reality. Curr Hypertens Rep. 2006 Oct;8(5):403-8.
148. Hayden MR, Kolb L, Chowdbury N, Karuparthi PR, Khanna R, Sowers JR. Detecting microalbuminuria and taking action in the cardiometabolic syndrome and type 2 diabetes mellitus. Mo Med. 2006 Sep- Oct;103(5):533-8.
149. Khan KA, Govindarajan G, Whaley-Connell A, Sowers JR. Diabetic hypertension. Heart Fail Clin. 2006 Jan;2(1):25-36.
150. Sarafidis PA, Whaley-Connell A, Sowers JR, Bakris GL. Cardiometabolic syndrome and chronic kidney disease: what is the link? J Cardiometab Syndr. 2006 Winter;1(1):58-65.
151. Hayden MR, Stump CS, Sowers JR. Introduction: organ involvement in the cardiometabolic syndrome. J Cardiometab Syndr. 2006 Winter;1(1):16-24.
152. Hayden MR, Chowdhury N, Govindarajan G, Karuparthi PR, Habibi J, Sowers JR. Myocardial myocyte remodeling and fibrosis in the cardiometabolic syndrome. J Cardiometab Syndr. 2006 Fall;1(5):326-33.
153. Gonzalez GL, Manrique CM, Sowers JR. High cardiovascular risk in patients with diabetes and the cardiometabolic syndrome: mandate for statin therapy. J Cardiometab Syndr. 2006 Summer;1(3):178-83.
154. Whaley-Connell A, Pavey BS, Chaudhary K, Saab G, Sowers JR. Renin-angiotensin-aldosterone system intervention in the cardiometabolic syndrome and cardio-renal protection. Ther Adv Cardiovasc Dis. 2007Oct;1(1):27-35. Review.
155. Romayne Kurukulasuriya L, Athappan G, Saab G, Whaley Connell A, Sowers JR. HMG CoA reductase inhibitors and renoprotection: the weight of the evidence. Ther Adv Cardiovasc Dis. 2007 Oct;1(1):49-59.
156. Thomson SP, Stump CS, Kurukulasuriya LR, Sowers JR. Adrenal steroids and the metabolic syndrome. Curr Hypertens Rep. 2007 Dec;9(6):512-9.
157. Hayden MR, Goldsmith D, Sowers JR, Khanna R. Calciphylaxis: calcific uremic arteriolopathy and the emerging role of sodium thiosulfate. Int Urol Nephrol. 2008;40(2):443-51.
158. Bakris G, Stockert J, Molitch M, Zhou Q, Champion A, Bacher P, Sowers J; STAR Investigators. Risk factor assessment for new onset diabetes: literature review. Diabetes Obes Metab. 2009 Mar;11(3):177-87. Epub 2008 Jun 16.
159. Gardner M, Gardner DW, Sowers JR. The cardiometabolic syndrome in the adolescent. Pediatr Endocrinol Rev. 2008 Aug;5 Suppl 4:964-8.
160. Addison S, Stas S, Hayden MR, Sowers JR. Insulin resistance and blood pressure. Curr Hypertens Rep. 2008 Aug;10(4):319-25.
161. Lastra-Gonzalez G, Manrique-Acevedo C, Sowers JR. The role of aldosterone in cardiovascular disease in people with diabetes and hypertension: an update. Curr Diab Rep. 2008;8(3):203-7.
162. Hayden MR, Patel K, Habibi J, Gupta D, Tekwani SS, Whaley-Connell A, Sowers JR. Attenuation of endocrine-exocrine pancreatic communication in type 2 diabetes: pancreatic extracellular matrix ultrastructural abnormalities. J Cardiometab Syndr. 2008 Fall;3(4):234-43.
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163. Khan KA, Sowers JR. Surgical treatment of the cardiometabolic syndrome and obesity. J Cardiometab Syndr. 2008 Fall;3(4):254-7.
164. Sowers JR. Endocrine functions of adipose tissue: focus on adiponectin. Clin Cornerstone. 2008;9(1):32-8; discussion 39-40.
165. Saab G, Whaley-Connell AT, Khanna R, Sowers JR. Therapy for the altered mineral metabolism of chronic kidney disease: implications for vascular calcification. Ther Adv Cardiovasc Dis. 2007 Dec;1(2):107-12.
166. Kurukulasuriya LR, Stas S, Lastra G, Manrique C, Sowers JR. Hypertension in obesity. Endocrinol Metab Clin North Am. 2008;37(3):647-62.
167. Nistala R, Whaley-Connell A, Sowers JR. Redox control of Renal Function and Hypertension. Antioxid Redox Signal. 2008;10(12):2047-2090.
168. Manrique C, Lastra G, Palmer J, Gardner M, Sowers JR. Aspirin and Diabetes Mellitus: revisiting an old player. Ther Adv Cardiovasc Dis. 2008 Feb;2(1):37-42.
169. McGill JB, Sowers JR, Weber M, et al. Progress and controversies: treating obesity and insulin resistance in the context of hypertension. J Clin Hypertens (Greenwich). 2009;11(1):36-41.
170. Nistala R, Wei Y, Sowers JR, Whaley-Connell A. Renin-angiotensin-aldosterone system-mediated redox effects in chronic kidney disease. Transl Res. 2009;153(3):102-113.
171. Mason RP, Giles TD, Sowers JR. Realities of newer beta-blockers for the management of hypertension. J Clin Hypertens (Greenwich). 2009 Jul;11(7):369-75.
172. Manrique C, Lastra G, Gardner M, Sowers JR. The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress. Med Clin North Am. 2009;93(3):569-82.
173. Bichu P, Nistala R, Khan A, Sowers JR, Whaley-Connell A. Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study. Vasc Health Risk Manag. 2009;5(1):129-40.
174. Sowers JR, Whaley-Connell A, Epstein M. Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension. Ann Intern Med. 2009;150(11):776-83.
175. Manrique C, Giles TD, Ferdinand KC, Sowers JR. Realities of newer beta-blockers for the management of hypertension. J Clin Hypertens (Greenwich). 2009;11(7):369-75.
176. Gardner M, Palmer J, Manrique C, Lastra G, Gardner DW, Sowers JR. Utility of aspirin therapy in patients with the cardiometabolic syndrome and diabetes. J Cardiometab Syndr. 2009;4(2):96-101.
177. Hanna-Moussa A, Kurukulasuriya LR, Sowers JR. Malignant pheochromocytoma presenting with uncontrolled hypertension after kidney transplant. J Clin Hypertens. 2010;12(2):105-8.
178. Whaley-Connell A, Johnson MS, Sowers JR. Aldosterone: role in the cardiometabolic syndrome and resistant hypertension. Prog Cardiovasc Dis. 2010;52(5):401-9.
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179. Allcock DM, Sowers JR. Best strategies for hypertension management in type 2 diabetes and obesity. Curr Diab Rep. 2010;10(2):139-44.
180. Ruilope L, Izzo J, Haller H, Waeber B, Oparil S, Weber M, Bakris G, Sowers J. Prevention of microalbuminuria in patients with type 2 diabetes: what do we know? J Clin Hypertens (Greenwich). 2010;12(6):422-30.
181. Lastra G, Dhuper S, Johnson MS, Sowers JR. Salt, aldosterone, and insulin resistance: impact on the cardiovascular system. Nat Rev Cardiol. 2010;7:577-584.
182. Bakris G, Vassalotti J, Ritz E, Wanner C, Stergiou G, Molitch M, Nesto R, Kaysen GA, Sowers JR. National Kidney Foundation consensus conference on cardiovascular and kidney diseases and diabetes risk: an integrated therapeutic approach to reduce events. Kidney Int. 2010;78(8):726-36.
183. Ren J, Pulakat L, Whaley-Connell A, Sowers JR. Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J Mol Med. 2010;88(10):993-1001.
184. Kurukulasuriya LR, Sowers JR. Therapies for type 2 diabetes: lowering HbA1c and associated cardiovascular risk factors. Cardiovasc Diabetol. 2010;9(1):45.
185. Hayden MR, Yang Y, Habibi J, Bagree SV, Sowers JR. Pericytopathy: Oxidative stress and impaired cellular longevity in the pancreas and skeletal muscle in metabolic syndrome and type 2 diabetes. Oxid Med Cell Longev. 2010 Sep 1;3(5).
186. Yang Y, Hayden MR, Sowers S, Bagree SV, Sowers JR. Retinal redox stress and remodeling in cardioxmetabolic syndrome and diabetes. Oxid Med Cell Longev. 2010 Nov 1;3(6):392-403.
187. Whaley-Connell A, McCullough PA, Sowers JR. The role of oxidative stress in the metabolic syndrome. Rev Cardiovasc Med. 2011;12(1):21-9.
188. Pulakat L, Demarco VG, Ardhanari S, Chockalingam A, Gul R, Whaley-Connell AT, Sowers JR. Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities. Am J Physiol Regul Integr Comp Physiol. 2011;301(4):R885-95.
189. Kurukulasuriya LR, Stas S, Lastra G, Manrique C, Sowers JR. Hypertension in obesity. Med Clin North Am. 2011 Sep;95(5):903-17.
190. Pulakat L, Aroor AR, Gul R, Sowers JR. Cardiac insulin resistance and microRNA modulators. Exp Diabetes Res. 2012;2012:654904.
191. Garcia-Touza M, Sowers JR: Evidence-based hypertension treatment in patients with diabetes. J Clin Hypertens (Greenwich). 2012;14(2):97-102.
192. Mandavia CH, Pulakat L, DeMarco V, Sowers JR. Over-nutrition and metabolic cardiomyopathy. Metabolism. 2012;61(9):1205-1210.
193. Whaley-Connell A, Sowers JR. Oxidative stress in the cardiorenal metabolic syndrome. Curr Hypertens Rep. 2012;14(4):360-365.
BOO K C H A P TER S 1. Standley PR, Ram JL, Sowers JR. The vasculature as an insulin-sensitive
tissue.- implications of insulin and insulin-like growth factors in hypertension,
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diabetes, atherosclerosis and arterial smooth muscle growth. In Crass, BF (ed), Calcium Regulating Hormones and Cardiovascular Disease. CRC Press, Boca Raton, Florida1995 pp 275-293.
2. Levy J, Sowers JR. Intracellular Ca2+ and insulin action. Possible role in the pathogenesis of Syndrome X In: Foa PP and Walsh MF (eds) Ion Channels and Ion Pumps: Metabolic and Endocrine Relationships in Biology and Clinical Medicine Vol 6, Springer- Verlag pp 116-136, 1993.
3. Sowers JR, Khoury S. Hypertension and atherosclerosis: Role of calcium antagonists as antiatherogenic agents with an emphasis on clinical trials. in Mu lti p l e Ri s k Fac t o r s i n C a r d i o v a s cu l a r D i s e a s e, edited by AM Gotto, C Lenfant, R Paoletti, A Zanchetti. Raven Press, New York 1991.
4. Imam K, Khoury S, Sowers JR. Hypertension. In: Current Nephrology, eds. Gonick HC, Mosby- Year Book, Inc., St. Louis, MO pp ]65-188,1994.
5. Khoury SA, Imam I, Sowers JR. Syndrome X.- Is it linked through the Y chromosome. In: ABCs of hypertensive Therapy, ed Messerli, F Authors Publishing House, New York, pp 213-222, 1994.
6. Sowers JR, Standley PR, Tuck ML, Ram JL. Calcium and calcium-regulatory hormones in hypertension. In: Hypertension: Physiology, Diagnosis and Management, Second Edition, eds. Laragh JH, Brenner BM. Raven Press Ltd., New York, NY pp 1155-1165, 1995.
7. Sowers JR, Mason BA, Dominguez LJ, Cotton DB, Sokol RJ. Cardiovascular and renal profile in normal pregnancy. In: Principles and Practice of nephrology, eds. Jacobson, Striker and Klahr, Mosby Year-Book, St. Louis, MO 65 pp 426-430, 1995.
8. Sowers JR. Anti hlypertensive therapy In.- Therapy for Diabetes Mellitus and Related Disorders, ed Lebovitz HE, Second Edition, American Diabetes Association, Inc., Alexandria, VA, pp 204-212, 1994.
9. Sowers JR. Actions of insulin and IGF-I on vascular smooth muscle cation and glucose metabolism In: Pharmacological Control of Calcium and Potassium Homeostasis. eds Godfraind T, Mancia G, Abbracchio MP, Aguilar-Bryan L, Govoni S., Kluwer Academic Publishers and Fondazione Giovanni Lorenzini, Dordrecht, Netherlands pp]29-137, 1995.
10. Sowers JR. Metabolic changes associated with isradipine and hydrochlorothiazide in MIDAS: Effects on serum cations and uric acid In: Pharmacological Control of Calcium and Potassium Homeostasis. eds Godftaind T, Mancia G, Abbracchio MP, Aguilar-Bryan L, Govoni S. Kluwer Academic Publishers and Fondazione Giovanni Lorenzini, Dordrecht, Netherlands pp] 95-198, 1995.
11. Afonso LC, Sowers JD. Effects of aging on cardiovascular baroreflex function. 3rd International Congress on Hypertension in the Elderly, Rome, Italy February, In: Senile Hypertension ’95, V. Marigliano, A. Scuteri, Eds. Casa Editrice Scientifica Internazionale, Rome, Italy 1995, pp 95-107.
12. Dominguez LJ, Peuler JD, Sowers JR. Endocrine regulation of vascular smooth muscle intermediary metabolism. In: Contemporary Endocrinology:
55
Endocrinology of the Vasculature. JR Sowers (ed), Humana Press Inc., Totowa, NJ, 1996, pp 325-339.
13. Bakris GL, Standley PR, Palant CE, Walsh MF, Sowers JR. Analogy between endothelial mesangial cell and endothelial vascular smooth muscle interactions: role of growth factors and mechanotransduction, In: Contemporary Endocrinology: Endocrinology of the Vasculature. JR Sowers (ed), Humana Press, Totowa NJ1996, pp 341-355.
14. Siddiqui MA, Sowers JR. Method of Hypertension, In: Conn’s Current Therapy. RE Rakel (ed), W.B. Saunders Co., Philadelphia, PA, 1997 pp 303-324.
15. Rajkumar V, Afonso LC, Steinberg J, Farrow S, Sowers JR. Metabolic and Cariovascular Manifestations of hypertension in the elderly. In: Recent Advances in Geriatrics. Barbagallo M, Licata G and Sowers JR (ed) Plenum Press, New York, NY, 1998.
16. Davidoff A, Walsh MF, Marsh J, Sowers JR. Abnormalities of Cardiovascular Calcium Metabolism Associated with Diabetes Mellitus and Metabolic Hypertension. In: Calcium Antagonists in Clinical Medicine 2nd Edition, M. Epstein (ed), Hanley & Belfus, Inc, Philadelphia, PA, 1998 pp 27-34.
17. Siddiqui MA, Reddy S, Sowers JR. Pheochromocytoma In:Principles and Practice of Emergency Medicine. Schwartz GR (ed). Williams and Wilins, Baltimore, MD, pp 979-982, 1998.
18. Sowers JR, Epstein M. Risk factors for arterial disease in diabetes:hypertension. In:Diabetic Angiopathy. Tooke JE (ed), Arnold Publishers, London, UK 1999, pp 45-63.
19. Ali SS, Lester MA, Sowers JR. Metabolic abnormalities in Hypertension. In: Pathophysiology. 2000, pp110-118.
20. Guzmán CB, Sowers JR. Medical consequences of obesity in women In: Infertility and Reproductive Medicine Clinics of North America. Kowalczyk, C (ed). W.B. Saunders, Philadelphia, PA 2000, pp 1047-9422.
21. Sowers JR, Neutel JM, Weir MR. Diuretics in hypertension therapy. In: Hypertension Medicine. Weber MA (ed). Humana Press, Totowa, NJ 2000, pp. 285-288.
22. Sowers KMR, Sowers JR. Diabetes and hypertension. In: Hypertension Medicine. Weber MA (ed). Humana Press, Totowa, NJ 2000, pp. 375-381.
23. Sowers JR. Diabetes and hypertension. In: Contemporary Cardiology: Diabetes and Cardiovascular Disease. Edited by M.T. Johnstone and A. Veves. Humana Press, Totowa, NJ, 2001, pp123-129
24. Sowers KM, Sowers JR. Pheochromocytomas. In: Manual of Endocrinology and Metabolism (3rd edition). Editor Lavin N. Llilppincott Williams & Wilkins, Philadelphia, PA. 2002, pp139-144.
25. Victorina WM, Rydstedt LL, Sowers JR. Clinical disorders of vasopressin. In: Manual of Endocrinology and Metabolism (3rd edition). Editor Lavin N. Lilppincott Williams & Wilkins, Philadelphia, PA. 2002, pp 68-82.
26. Stern N, Sowers J, Tuck ML. Pathophysiology of hypertension in diabetes. In: Diabetes Mellitus (3rd edition). Editor LeRoith D, Taylor SI, Olefsky JM. Lippincott Williams & Wilkins, Philadelphia, PA. 2004, pp 1377-1400.
28. A Messerli, E Grossman, J Sowers, F Messerli. Textbook of Cardiovascular Medicine. Lippincott Williams & Wilkins, New York, 2004.
29. Tan AS, Brietzke SA, Gardner DW, Sowers JR. Obesity, Diabetes, and Hypertension. In: Obesity and Diabetes. Humana Press, Totowa, New Jersey. 2006, pp 169-192.
30. McFarlane S, Sica D, Sowers JR. Stroke in patients with diabetes and hypertension. In: The Year In Hypertension. Atlas Medical Publishing, Oxford, UK. 2006, pp 235-248.
31. Stas S, McFarlane S, Sowers JR. Management of Hypertension in Cardiometabolic Syndrome and Diabetes with Associated Nephropathy. In: Hypertension Principles and Practice. Taylor and Francis, Boca Raton, FL. 2005, pp 631-650.
32. Whaley-Connell AT, Sowers JR, Hypertension Primer: Essentials in High Blood Pressure, chapter 47, 2007
33. Mugo MN, Link D, Stump C, Sowers JR. Insulin Resistance and Diabetes in Hyptertension. In: Comprehensive Hypertension. Mosby. 2007, pp 681-692.
34. Sowers JR, Allcock DM, Whaley-Connell AT. Hypertension. A Companion to Braunwald’s Heart Disease. Second Edition. Hypertension and Diabetes Mellitus: An Update. Saunders, an imprint of Elevier Inc., Philadelphia, PA. 2013.
35. Garcia-Touza M, Sowers J. Diabetes and Cardiovascular disease. Diabetes and Hypertension. Editors McFarlane/Babis, Springer 2012.
36. Aroor A, Mandavia CH, Sowers JR. Insulin resistance and heart failure: molecular mechanisms. Glucolipotoxicity and the Heart. Heart Failure Clinics. Toth and Raghavan. WB Saunders. Philadelphia PA. 2012.
BOOK S 1. Hypothalamic Hormones, Editor JR Sowers. Dowden, Hutchinson & Ross Inc.
Stroudsberg, PA, Nov. P:342, 1980.2. The Endocrinology of Aging, JR Sowers and J Felicetta, ed. Raven Press, New
York, 1988.3. Hypertension Primer, JL Izzo, HR Black ed. TL Goodfriend, JR Sowers, FH
Messerli, JA Cutler, SG Sheps, D Vidt, section eds. From the Council on High Blood Pressure, American Heart Association, Dallas, Texas, 1993.
4. Contemporary Endocrinology: Endocrinology of the Vasculature. JR Sowers (ed), Humana Press, Totowa, NJ, 1996.
5. Recent Advances in Geriatrics; M Barbagallo, G Licata and JR Sowers eds. Plenum Press, New York , NY; 1998.
6. Hypertension Primer (3rd Edition) The Essentials of High Blood Pressure. Section Editors: TL Goodfriend, JR Sowers, AB Weder, LJ Appel, DG Vidt, SG Sheps, DA Sica. Senior Editors: JL Izzo, Jr, HR Black. American Heart Association. Lippincott Williams & Wilkins, Philadelpha, PA, 2003.
7. Molecular Mechanisms in Hypertension. RN Re, DJ DiPette, EL Schiffrin, JR Sowers Taylor & Francis Group, London and New York, 2006.
8. Diabetes and Hypertension: Moser M, Sowers JR 2005; 2008
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9. Hypertension and Cardiovascular Disease. A Whaley-Connell, K Sowers, JR Sowers. Contemporary Diabetes: The Diabetic Kidney. Humana Press Inc., Totowa, NJ, 2006.
10. Diabetes in Women, Pathophysiology and Therapy. Cardiovascular Disease in Women with Diabetes. Gajula S, Reddy A, Kurukulasuriya LR, Manrique C, Lastra G, Sowers JR. Humana Press Inc., Springer Science+Business Media LLC, New York, New York, 2009.
11. Hypertension and Hormone Mechanisms. Insulin Resistance and Hypertension. JR Sowers. Humana Press Inc. Totowa, NJ, 2007.
12. Hypertension. A Companion to Braunwald’s Heart Disease. Hypertension and Diabetes Mellitus. Mugo MN,Stump CS, Rao PG, Sowers JR. Saunders, an imprint of Elevier Inc., Philadelphia, PA, 2007.
13. Hypertension. A Companion to Braunwald’s Heart Disease. Second Edition. Hypertension and Diabetes Mellitus: An Update. Sowers JR, Allcock DM, Whaley-Connell AT. Saunders, an imprint of Elevier Inc., Philadelphia, PA, 2013.
14. Hypertension in Diabetes.Jindal A, Naqvi SH, Waqar Salam M, Sowers JR.Editors. In: De Groot LJ, Beck-Peccoz P, Chrousos G, Dungan K, Grossman A, Hershman JM, Koch C, McLachlan R, New M, Rebar R, Singer F, Vinik A, Weickert MO, editors. Endotext [Internet]. South Dartmouth (MA): DText.com, Inc.; 2000-2014 Jan 3.
