Viral DiseasesViral Diseases

Clinical classificationClinical classification

Vesicle form ： vesicles dominated,such as Herpes Simplex ,Herpes Zoster and Varicella. Erythema form ： Erythema dominated ， such as Measles 、 Rubella and Erythema Infectioum. Neoplasm form ： Verruca vulgaris,Verruca planae and Molluscum Contagiosum. STD form ： Lymphogranuloma venereum.

Herpes simplexHerpes simplex

VericellaVericella

Herpes zosterHerpes zoster

Verruca vulgarisVerruca vulgaris

Verruca Verruca planaplana

Herpes zosterHerpes zoster

Zoster is a kind of acute skin infection caused by the varicella-zoster virus.

Manifestation: unilaterlly ; within the distribution of sensory nerve; little blisters in population; with neuralgia and lymphadenectasis; less recurrence after recovery

Etiology and MechanismEtiology and Mechanism

varicella-zoster virus.

humanhuman

varicellavaricella

Latent infLatent infectionection

Virus in the ganglia of cranial or spinal sensory nerve

InduInducing fcing factoractorss

Herpes zoHerpes zosterster

infectinfect

Clinical manifestationClinical manifestationPredilection human beings ： adult

Early symptoms ： moderate fever,malaise,local lymp

hadenectasis and neuralgia. Eruption characteristic ： （ 1 ） erythema papule blister

（ 2 ） distribute unilaterally in band within peripheral nerve （ 3 ） blisters in population （ 4 ） neuralgia and local lymphadenectasisPredilection sites ： chest,waist,neck and the distribut

ion regions of trigeminal nerve.

course ： 2 － 4 weeks

Special form Zoster (Special form Zoster (Ⅰ)Ⅰ)

Herpes zoster without eruptionsAbortive type Herpes Zoster Bullous,hemorrhagic or necrotic Herpes ZosterDisseminated Herpes Zoster

Herpes ZosterHerpes Zoster （（ hemorrhagihemorrhagi

c)c) ））

Special Herpes ZosterSpecial Herpes Zoster （（ⅡⅡ））

virus Motor neurons virus Motor neurons MyastheniaMyasthenia ，， skin paralysisskin paralysisvirus geniculate ganglion(involvment of thevirus geniculate ganglion(involvment of the facial and auditory nerves)facial and auditory nerves) RamseyRamsey －－ Hunt syndrome Hunt syndrome : : Zoster of the external ear, ear pain, Zoster of the external ear, ear pain, facial paralysis, vertigo. facial paralysis, vertigo.

DiagnosisDiagnosis

Lesions:erythema,papule and blisters; Blisters in population; distribute unilaterally in band within peripheral nerve; with neuralgia.

Treatment principlesTreatment principles The prevention of neuralgiaantivirus ： ACV 0.2 q4h X 5 － 10d Valaciclovir 0.3bid X 5 － 10dantiinflammationTopical treatmentPrevent secondary infection

Molluscum contagiosa Molluscum contagiosa

papule dermatosis,caused by MCV characteristics: smooth surfaced and dome shaped

pearly papules; central umbilication; molluscum body.

Etiology and MechanismEtiology and Mechanism

Molluscum Contaguosum Virus transmitted by direct skin to skin contact; or auto-inoculation

Clinical manifestationClinical manifestation

Predilection human beingsPredilection human beings ：： children and youtchildren and youth. Latent time: 2-3 weeks.h. Latent time: 2-3 weeks.

FeatureFeature of lesionsof lesions ：： 3 to 5mm in diameter3 to 5mm in diameter semisphere-like , pearly papulessemisphere-like , pearly papules central umbilicationcentral umbilication squeeze out white cheese-like substancesqueeze out white cheese-like substance number: several to many number: several to many no confluenceno confluence

Clinical manifestationClinical manifestationPredilection sitesPredilection sites ：： trunk, extremities,scrotum and eyelidtrunk, extremities,scrotum and eyelid sometimes lip, tone and sometimes lip, tone and buccal mucosa are involved. buccal mucosa are involved.

coursecourse ：： 66 －－ 9months9months ，， individually:4individually:4 －－ 5years or longer.5years or longer.Symptoms: NO or moderate itching.Symptoms: NO or moderate itching.

TreatmentTreatmentIsolationNicking with trichloracetic ac

id(33 ％ ) 10 ％ potassium hydroxide

Definition scabies is one kind of parasitosis caused by Sarcoptes scabies which invade th

e skin of the finger webs,antecubital fossae, the lower abdomen,genitals and scrotum ect, and characterized by pruritic papular, bullous lesions and also burrows.

transimitted by skin to skin contact

ScabiesScabies

Etiology Etiology

Life of Life of Sarcoptes scabies

adultadult femalefemale

malemale

matingmatingFemale ovulateFemale ovulate

Male diedMale diedovumovum

3-4 da3-4 daysys

larvalarva nymphaenymphae adultadultTwice ecdysisTwice ecdysis

2-3 day2-3 dayss

7-14days 7-14days

Infection styleInfection style ：： mostly direct skin to skin contactmostly direct skin to skin contact，，

a few infected by indirect contacta few infected by indirect contact

Clinical manifestationClinical manifestation ：：Predilection human beings ： anyone Feature of eruption ： 1 papulovesicles with no confluence 2 burrows 3 scabies nodule Predilection sites: the finger web,medial wrist, antecubital fossae,areas around the waist, the lo

wer abdomen, genitals and groins ect.Intense itch: especially in night

The finger webThe finger web

DiagnosisDiagnosis eruption ： burrows papulovesicles and blisters scrotum nodulespredilection sites: especially the finger

web and external genitals. intense itch: especially in night infect collectively:the same patients in

one family. most convinced evidence: Sarcoptes sc

abies or its eggs.

Differential diagnosisDifferential diagnosis

PruritusPapular urticariaPediculosis

TreatmentTreatment

10% Oint. Sulfur10% Oint. Sulfur

Solution of killing Solution of killing Sarcoptes scabies

Cream. 10Cream. 10 ％ ％ CrotamitonCrotamiton