26
till date. Volume 11 Number 01 January 2020
till date.
Volume 11 Number 01 January 2020
Indian Journal of Public Health Research & Development
EXECUTIVE EDITOR
Prof. Vidya SurwadeDeptt. of Community Medicine, Dr Baba Saheb Ambedkar, Medical College & Hospital, Rohini, Delhi
INTERNATIONAL EDITORIAL ADVISORY BOARD
1. Dr. Abdul Rashid Khan B. Md Jagar Din, (Associate Professor) Department of Public Health Medicine, Penang Medical College, Penang, Malaysia
2. Dr. V Kumar (Consulting Physician) Mount View Hospital, Las Vegas, USA
3. Basheer A. Al-Sum, Botany and Microbiology Deptt, College of Science, King Saud University,
Riyadh, Saudi Arabia
4. Dr. Ch Vijay Kumar (Associate Professor) Public Health and Community Medicine, University of Buraimi, Oman
5. Dr. VMC Ramaswamy (Senior Lecturer)Department of Pathology, International Medical University, Bukit Jalil, Kuala Lumpur
6. Kartavya J. Vyas (Clinical Researcher)Department of Deployment Health Research, Naval Health Research Center, San Diego, CA (USA)
7. Prof. PK Pokharel (Community Medicine)BP Koirala Institute of Health Sciences, Nepal
NATIONAL SCIENTIFIC COMMITTEE
1. Dr. Anju D Ade (Professor)Community Medicine Department, SVIMS, Sri Padamavati Medical College,Tirupati, Andhra Pradesh.
2. Dr. E. Venkata Rao (Associate Professor) Community Medicine,Institute of Medical Sciences & SUM Hospital, Bhubaneswar, Orissa.
3. Dr. Amit K. Singh (Associate Professor) Community Medicine,VCSG Govt. Medical College, Srinagar – Garhwal, Uttarakhand
4. Dr. R G Viveki (Associate Professor) Community Medicine,Belgaum Institute of Medical Sciences, Belgaum, Karnataka
5. Dr. Santosh Kumar Mulage (Assistant Professor)Anatomy, Raichur Institute of Medical Sciences Raichur(RIMS), Karnataka
6. Dr. Gouri Ku. Padhy (Associate Professor) Community and FamilyMedicine, AII India Institute of Medical Sciences, Raipur
7. Dr. Ritu Goyal (Associate Professor) Anaesthesia, Sarswathi Institute of Medical Sciences, Panchsheel Nagar
8. Dr. Anand Kalaskar (Associate Professor)Microbiology, Prathima Institute of Medical Sciences, AP
9. Dr. Md. Amirul Hassan (Associate Professor)Community Medicine, Government Medical College, Ambedkar Nagar, UP
10. Dr. N. Girish (Associate Professor) Microbiology, VIMS&RC, Bangalore
11. Dr. BR Hungund (Associate Professor) Pathology, JNMC, Belgaum.
12. Dr Sartaj Ahmad, PhD Medical Sociology, Associate Professor, Swami Vivekananda Subharti University Meerut UP India
13. Dr Sumeeta Soni (Associate Professor)Microbiology Department, B.J. Medical College, Ahmedabad, Gujarat,India
NATIONAL EDITORIAL ADVISORY BOARD
1. Prof. Sushanta Kumar Mishra (Community Medicine)GSL Medical College – Rajahmundry, Karnataka
2. Prof. D.K. Srivastava (Medical Biochemistry)Jamia Hamdard Medical College, New Delhi
3. Prof. M Sriharibabu (General Medicine) GSL Medical College, Rajahmundry, Andhra Pradesh
4. Prof. Pankaj Datta (Principal & Prosthodentist)Indraprastha Dental College, Ghaziabad
NATIONAL EDITORIAL ADVISORY BOARD
5. Prof. Samarendra Mahapatro (Pediatrician)Hi-Tech Medical College, Bhubaneswar, Orissa
6. Dr. Abhiruchi Galhotra (Additional Professor) Community and FamilyMedicine, AII India Institute of Medical Sciences, Raipur
7. Prof. Deepti Pruthvi (Pathologist) SS Institute of Medical Sciences &Research Center, Davangere, Karnataka
8. Prof. G S Meena (Director Professor)Maulana Azad Medical College, New Delhi
9. Prof. Pradeep Khanna (Community Medicine)Post Graduate Institute of Medical Sciences, Rohtak, Haryana
10. Dr. Sunil Mehra (Paediatrician & Executive Director)MAMTA Health Institute of Mother & Child, New Delhi
11. Dr Shailendra Handu, Associate Professor, Phrma, DM (Pharma, PGI Chandigarh)
12. Dr. A.C. Dhariwal: Directorate of National Vector Borne Disease Control Programme, Dte. DGHS, Ministry of Health Services, Govt. of India, Delhi
Print-ISSN: 0976-0245-Electronic-ISSN: 0976-5506, Frequency: Quarterly (Four issues per volume)
Indian Journal of Public Health Research & Development is a double blind peer reviewed international journal. It deals with all aspects of Public Health including Community Medicine, Public Health, Epidemiology, Occupational Health, Environmental Hazards, Clinical Research, and Public Health Laws and covers all medical specialties concerned with research and development for the masses. The journal strongly encourages reports of research carried out within Indian continent and South East Asia.
The journal has been assigned International Standards Serial Number (ISSN) and is indexed with Index Copernicus (Poland). It is also brought to notice that the journal is being covered by many international databases. The journal is covered by EBSCO (USA), Embase, EMCare & Scopus database. The journal is now part of DST, CSIR, and UGC consortia.
Website : www.ijphrd.com©All right reserved. The views and opinions expressed are of the authors and not of the Indian Journal of Public Health Research & Development. The journal does not guarantee directly or indirectly the quality or efcacy of any product or service featured in the advertisement in the journal, which are purely commercial.
Editor
Dr. R.K. SharmaInstitute of Medico-legal Publications
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Printed, published and owned by
Dr. R.K. SharmaInstitute of Medico-legal Publications
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Published at
Institute of Medico-legal Publications
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I
Indian Journal of Public Health Research & Development
www.ijphrd.com
Contents
Volume 11, January 01 January 2020
1. Study protocol: A Randomised Controlled Trial on E�ectiveness of a Worksite Health Intervention
on Common Musculoskeletal Problems and Work-Related Quality of Life (WRQoL) among Female
Workers in the Garment Manufacturing Sectors ................................................................................................1
A. Santham Lilly Pet, Timsi Jain, Bobby Joseph, Pethuru Devadason, Gayathri M
2. Health of the Elderly in India: A Socio-Legal Study .........................................................................................7
Aarti, J.K.Mittal
3. General Awareness of Diabetes Mellitus among a Hospital Population in Chennai: A Survey ......................12
Sridhar M., Abilasha Ramasubramanian
4. Vitamin D De�ciency in Rural Area of Gautam Buddh Nagar: An Observational Study ...............................16
Vijay Deepak Verma, Ajai Kumar Garg, Suresh Babu, Ashish Satyarthi
5. Identifying the Status of Menstrual Hygiene Management ..............................................................................20
Amrita Shilpi, Rajasree Roy, Gobina, Spriha Roy
6. E�ect of Strengthening of Scapular Stabilizers in Treatment of Rounded Shoulder Posture in Dental
Students ............................................................................................................................................................27
Ankita M. Patil, Sayali Gijare
7. Elder Abuse in Indian Setting–A Misconception or a Reality– A Deductive Analysis ...................................31
Anusha Rashmi, Linda Sequeira, Prianka Shashi Kumar, Rashmi
8. A Study on Women Entrepreneurs Dealing Through Stress ............................................................................35
Archana R.V., K. Vasanthi Kumari
9. E�ect of Bilateral Scapular Muscles Strengthening on Dynamic Balance in Post Stroke Individuals ............38
Arpan Dhoka, G. Varadharajulu
10. In Vitro Antibacterial and Anticancer Study of Bioactive Compounds Isolated from Punica Grantum Peel..45
Arunava Das, J. Bindhu, M. Bharath, Nithin Johnson, M. Jeevanantham
11. A Study on Utilization of Primary Health Care Services among the People Residing in a SEMI-
URBAN AREA ................................................................................................................................................53
B. Charumathi, D. Jayashri, S. Manisha, Aadithya, C. Hemanthkumar, Timsi Jain
12. An Empirical Relationship between Stress and Job Performance: A Study with Private School Teachers ....57
D.S. Premalatha, S. Subramanian
II13. Decision Tree Ensemble Techniques to Predict Thyroid Disease ....................................................................61
Dhyan Chandra Yadav, Saurabh Pal
14. A Descriptive Study to Assess the Knowledge on Child Birth Preparation among Primigravid Mothers
in a Selected Tertiary Care Hospital at Kelambakkam, Kanchipuram District, Tamilnadu, India ..................68
J. Chrislin Jebisha, R.J. Joey Persul, D. Joaniepriya
15. Lateral Periodontal Cyst Masquerading Dentigerous Cyst: A Rare Case Report ............................................72
Jagannath Patro, Swagatika Panda, Sreepreeti Champatyray, Alkananda Sahoo, Neeta Mohanty
16. Investigation of a Food Poisoning Outbreak in a Private Hostel in Kanchipuram District, Tamilnadu ..........76
Jayashri Damodharan, Prashanth Rajendiran, Charumathi Boominathan, Muthulakshmi Muthiah,
Gomathy Parasuraman, Ruma Dutta, Timsi Jain
17. A Review on Process of Data Mining Approaches in Healthcare Sectors .......................................................81
K. Baalaji, V. Khanaa
18. Prevalence of Musculoskeletal Pain among Manual Drummers and Electric Pad Drummers.........................86
K. Jothi Prasanna, S. Rahul Prabhu
19. E�ectiveness of Low Level Laser Therapy Versus Ultrasound Therapy with Plantar Fascia Streching
in Subjects with Plantar Fasciitis ......................................................................................................................93
K. Koteeswaran, Ramya K., Rajeshwari, Manikumar Muthiah, Sankara Kumaran Pandian
20. Evaluation of Temporomandibular Disk Position In Symptomatic Temporomandibular Disorder
Patients With Gnathological Splint Therapy Using Mri ..................................................................................98
K. Sridhar, M.S. Kannan, Faisaltajir, Gnanashanmugam
21. Antimicrobial E�cacy of Triphala as Root Canal Irrigating Solution in Infected Primary Teeth: An
Ex Vivo Study ................................................................................................................................................105
Kiran N.K., Nagalakshmi Chowdhary, Y. Sharada Devi Mannur, Neethu Elsa Varghese, Arvind
Sridhara, Pavana M.P.
22. Association between Urinary Cotinine Levels and Buccal Mucosal Micronuclei Cells of Smokeless
Tobacco Chewers Attending a Tertiary Care District Hospital ......................................................................109
Kiran S. Nikam, Kanchan C. Wingkar, Rajesh K. Joshi, Rajashekar K. Kallur
23. Balanced Diet: Knowledge and Practice of Adolescents ...............................................................................115
Krupa Reji, Leema Jacob, Liby Kuriakose, Linsha K., Maria Augustine, Maria George, Priya
Reshma Aranha
24. In�uence of Self-E�cacy on Student Engagement of Senior Secondary School Students ...........................120
Kundan, Bilkees Abdullah
25. Psychological E�ects of Trauma to Anterior Teeth .......................................................................................126
Lakshmi Nidhi Rao, Aditya Shetty, Mithra N. Hedge
26. E�ect of Aerobic Exercises on Selected Physiological Variables among College Long Distance Men
Athletes ...........................................................................................................................................................132
M. Senthil Kumar, P.R. Nagaraj, Ampili
27. A Descriptive Study to Assess the Knowledge on Pre-Menopausal Symptoms among Middle Aged
IIIWomen in a Selected Village at Kanchipuram District, Tamilnadu, India ....................................................136
M. Deepan Babu, S.Vasuki, K.Sangeetha, D. Joaniepriya
28. Health Care Services Under Consumer Protection Laws of Union Territories of Jammu and Kashmir:
A Socio-Legal Mapping .................................................................................................................................140
M.Z.M. Nomani, Ajaz Afzal Lone, Alaa K.K. Alhalboosi, Aijaj A. Raj, Zubair Ahmed
29. Comparison of Morphological Features of Second Cervical Vertebra between Genders Using
Computed Tomography ..................................................................................................................................146
Madhavan T.S., Sharath S., Rahul P. Kotian
30. Acceptance of PBL by Students to Learn Pre-Clinical Sciences ...................................................................152
Malini Dutta, K. Aditya, Dilip Mathai
31. E�ect of Dance Therapy on Stress and Anxiety in Working Women ............................................................158
Manali B. Badave, Khushboo Bathia, Smita Kanase, Amrutkuvar Jadhav
32. A Study on E�ect of Favorite Film Songs on Heart Rate Variability (HRV) and Heart Rate (HR) with
Moderate Exercise ..........................................................................................................................................163
Manibalanvijayaraman
33. A Proximate Analysis of Phytochemical in Sonalum Trilobatum after the Addition to Leavened Yeast
Goods with Sensory Evaluation .....................................................................................................................168
Manivel K., John R. William, Moyeenudin H.M.
34. Satisfaction Level of Physiotherapy Students in North India .........................................................................173
Manoj Malik, Charu Gera, Jaspreet Kaur, Vandana Yadav
35. Prevalence of Lumbar Lordosis in Middle-Aged Females .............................................................................179
Manpreet Bajaj, S. Anandh
36. Radiographic Evaluation of Di�erent Combinations of Zinc Oxide as an Obturating Material in
Pulpectomy: A Comparative in Vivo Study ...................................................................................................184
Kiran N.K., Nagalakshmi Chowdhary, Megha Kumar, Pavana M.P., Aravind Sridhara
37. Development of “Young Planning Clinic” Program as a Prevention Early in Adolescent Attitude in
Martapura River Areas ...................................................................................................................................190
Meitria Syahadatina N., Atikah Rahayu, Fauzie Rahman, Fahrini Yulidasari, Dian Rosadi, Nur Laily,
Hadianor
38. Patterns and Determinants of Utilization of Healthcarein Urban Field Practice Area of a Tertiary Care
Institute, Hyderabad ........................................................................................................................................195
Moniza Maheen, Fawwad M. Shaikh, Vaseem Anjum, A. Chandrasekhar
39. Awareness � Practice of Road Safety Measures among Under Graduate Medical Students of a
Medical College in Bengaluru, Karnataka .....................................................................................................199
Shyam A.C., Mubarak Nadeer
40. The E�ect of Eye-Hand Coordination Device on Coordination in Subjects with in-Coordination ...............203
MuzahidKadir Sheikh, Suraj B. Kanase
41. Prevalence of Depressive Symptoms among Incognizant Patients Visiting a Hospital .................................208
IVA. Vinita Mary, N. Manikandan, K. Pavithra, M. Nathiya, R. Kesavan
42. Intelligent System for Physically Challenged Person in Virtual Prototype Environment ..............................213
N. Prabhakaran, N.D. Bobby, M. Munireddy, G.S. Sivapriya
43. Health Insurance Utilisation Pattern in Two Districts of Karnataka ..............................................................218
Nagaraj Shet, Ghulam Jeelani Qadiri, Sunita Saldanha, Gayathri Kanalli S., Prajna Sharma
44. Study of Knowledge, Attitude and Practise (KAP) Regarding Swachh Bharat Mission Among High
School Students in Field Practise Area of Medical College in Dakshina Kannada, Karnataka .....................224
Nanjesh Kumar S., Jithin, Harshitha, Rashmi Kundapur, Sanjeev Badiger, Pavan Kumar
45. Association of Personality Traits, Life Satisfaction, Subjective Happiness and Oral Health Status in
School Teachers of Vikarabad ........................................................................................................................228
N. Sindhu Reddy, M. Monica, T. Abhinav Nithin, P. Parthasarathi Reddy, Irram Abbas Hameed, B.
Prathibha
46. E�ect of Structured Exercise Programme on Pulmonary Function and Physical Performance in
Geriatric Population ........................................................................................................................................234
Gaurav S. Chandolkar, Javid H. Sagar, Govindhan Vardharajulu
47. Comparative Evaluation of Depth of Cure of Bulk-�ll Composite Resin and Alkasite Restorative
Material by Vicker�s Hardness Test ...............................................................................................................238
Gowrish Bhat, Namrata Khanna, Mithra Nidarsh Hegde, Vandana Sadananda
48. Population Growth and its Impact on Public Health in India: A Legal Analysis ...........................................243
Hiranmaya Nanda, Shyamantak Misra
49. Evaluation of Malondialdehyde, Glutathione Peroxidase and Defensin Levels in Patients with and
without Periodontitis .......................................................................................................................................247
J. Hemashree, Sreedevi Dharman, Selvaraj
50. E�ect of Neurodynamic Sliding Technique on Hemiplegic Stroke Subjects with Hamstring Tightness ......252
J. Anandhraj, A. Kumaresan
51. To Compare the Flexural Properties of Three Commercially Available Heat Cure Denture Base Resins
After Water Immersion Over a Period of Three Months: An in Vitro Study .................................................256
Neha Chugh, Pradeep Sheriger, Dhanasekar Balakrishnan, Aparna Ichalangod Narayan
52. E�ect of Weight Bearing and Neurobic Exercises on Bone Health and Physical Function in Elderly
Individuals ......................................................................................................................................................262
Neha Dighe, S. Anandh, G. Varadharajulu
53. Knowledge, Attitude and Practice of Biomedical Waste Management in Nursing Sta� of a Private and
a Government Tertiary Care Teaching Hospital: A Comparative Study ........................................................268
Nishitha K., Alice Matilda Mendez, Nisha B., Timsi Jain
54. WTO and its Impact on Indian Pharmaceutical Production: A Legal Perspective.........................................274
Nitesh Kumar Srivastava
55. Prevalence and Molecular Characterization of Glucose-6-Phosphate Dehydrogenase De�ciency
among Brahmins and Muslims of Manipur, India ..........................................................................................279
VNongthombam Achoubi, Mohammad Asghar, Anand Kumar Gyanendra Singh Wahengbam, Soibam
Jibonkumar Singh, Kallur Nava Saraswathy, Benrithung Murry
56. E�cacy of Technology Basded Method to Improve Knowledge on Health Promoting Behaviour
towards Maternal Hypothyroidism among Primi Mothers with Hypothyroidism .........................................284
P.M. Arulmozhi Baskaran, Prasanna Baby
57. E�ect of Water Aerobic and Aerobic Exercise on VO2 Max Parameter among College Men Students .......290
P.R. Nagaraj, R. Senthil Kumar
58. Assessment of Di�erent Types of Malocclusion Using IOTN Index and Geographic Information
System: A Cross-sectional Observational Study ............................................................................................294
Bhagyalakshmi Avinash, Balasubramanian S., Ravikumar S., Suma Shekar, Avinash B.S.
59. Hair Mercury Exposure and Hypertension among Community Artisanal and Small Scale Gold Mining
in Banten, Indonesia .......................................................................................................................................300
Budi Hartono
60. E�ect of Lavender Oil Massage on Pain among Patients with Knee Osteoarthritis ......................................305
Enas Mahmoud El Sayed, Hanan Ahmed Al Sebaee, Heba Ahmed Mohammed, Zeinab Osman Nawito
61. How Soon Can You Expect to Get Pregnant after Discontinuing Reversible Contraceptive Method?
A Survival Analysis of the 2017 Indonesia Demographic and Health Survey Data ......................................311
Maria Gayatri, Budi Utomo, Meiwita Budiharsana
62. Reviving the Lost Extremity: A Case Report .................................................................................................316
Nitika Gupta, Jeewan Bachan Dhinsa, Urvashi Sukhija, Sanjeev Mittal
63. Lower Extremity Perfusion among Patient with Type 2 Diabetes Mellitusin a Tertiary Care Hospital,
Kochi ..............................................................................................................................................................320
Reshma�K��Sasi,�Ra�a�Islam,�Anjana�Sunil,�Anju�Markose
64. A Glimpse of Manual Scavanging in India ....................................................................................................326
Shailla Cannie, Aasavri Cannie
65. Out of Pocket Spending for Natal Care Services: A Comparative Analysis among High and Less
developed States in India ................................................................................................................................330
A.K. Ravisankar
66. Current Research in Neuropathology and Pharmacotherapy of Alzheimer�s Disease: A Review .................335
Amit Yadav, Prabhat Kumar Upadhyay, Manish Kumar, Vishal Kumar Vishwakarma, A. Pandurangan,
Pradeep Mishra
67. In Vitro Anticancer Study of Bioactive Compound Isolated from Musa Extract (Musa Acuminata) ...........341
Arunava Das, J. Bindhu, P. Deepesh, G. Shanmuga Priya, S. Soundariya
68. Optimized Feature Selection and Classi�cation in Microarray Gene Expression Cancer Data .....................348
B. Lakshmanan, T. Jenitha
69. Evaluation of Autonomic Dysfunction in Underweight, Normal Weight, Overweight and Obese
Patients with Chronic Obstructive Pulmonary Disease ..................................................................................354
Desai Nabil, Jyoti Ganai, Shobitha M., Nabi N.
VI70. E�ect of Exercise Program in Reducing Risk of Fall in Elderly People ........................................................360
Elizabeth J. Shende, Pranjali M. Gosavi, S. Anandh, Yogita A. Pawar
71. Regenerative Endodontics-The Future? A Questionnaire Based Study .........................................................364
Farhan Ariwala, Mahalaxmi Yelapure, Mithra N. Hegde, Darshana Devadiga, Upasana
72. Breast Cancer Screening: Are ‘At Risk Population� Known by Public Health Nurse Practitioners? ............370
G.M. Venkatesh, M. Sundar
73. Credibility of Health Care Advertising-An Empirical Understanding of its Multi-Dimensional
Structure and Scale Validation with Special Reference to Children�s Health Food Drinks ..........................375
Indu Manish Kumar
74. Association of Epicardial Adipose Tissue Thickness with Resting and Post-Exercise Cardiac Output
in Overweight and Obese Individuals ............................................................................................................381
Sridevi, Kalyana Chakravarthy Bairapareddy, Bhamini Krishna Rao, Arun G. Maiya, Gopala Krishna
Alaparthi, Krishnananda Nayak
75. The E�ectiveness of Health Belief Model as an Educational Intervention in Improvement of Oral
Hygiene: A Systematic Review ......................................................................................................................386
Nesa Aurlene, Sunayana Manipal, Rajmohan, Prabu D.
76. Do Stress and Resilience among Undergraduate Nursing Students Exist? ....................................................391
Priscilla Roselyn Sam, Premila Lee
77. Antibacterial Activity of Combination between Probiotic Milk and Mango Honey Against
Streptococcus Mutans .....................................................................................................................................395
Inaaroh��aachidah�A��ul�yyah,�Isnaeni,�Noor�Erma
78. Prevalence of Premarital Sex among Adolescents in Kulende, Sango in Ilorin South Local Governmrnt
Area, Kwara State, Nigeria .............................................................................................................................400
Oniyangi, Shuaib Olanrewaju, Jamiu Abdul Qudus Tosin, Umar Ibrahim Babangida, Ahmad Makama
Getso, Sindama Helen
79. Perceived E�ect of Sleep Deprivation on the Health of Undergraduates in Kwara State University,
Malete, Nigeria ...............................................................................................................................................405
Oniyangi, Shuaib Olanrewaju, Jamiu Abdul Qudus Tosin, Umar Ibrahim Babangida, Ahmad Makama
Getso, Sindama Helen
80. Noise Relationship with Complaints of Disorders of Hearing in Crafts Industry with Iron in Parigi
Moutong District .............................................................................................................................................410
Abdul Hamid, Abdul Rohim Tualeka
81. The Role Of Cultural Social Factor In Decision Making Of Choosing Female Family Planning
Contraception ..................................................................................................................................................414
Abdul Jalil Amri Arma, Surya Utama, Iskandar Muda
82. Epidemiology of Hypercholesterolemia among Adults in Samara City ........................................................419
Abid�Ahmad�Salman�Al‑Mahmood,�Ehan�Abdulhadi�Hussein�Al‑Shari�,�Asia�Abed�Al‑Mahmood
83. Corn Silk Based Ethosomal Gel: A New Treatment for Periodontitis in Diabetic Albino Rats a
VIIPrelimenary Study ..........................................................................................................................................425
Riuwpassa I.E., Kim YR, Tenrilili A.N.A., Untung J.S., Djamaludin N.S., Achmad M.H.
84. Circuit Training to Increase Cardiorespiratory Endurance in Male Basketball Players .................................431
Agung Wahyu Permadi, I. Made Wisnu Adhi Putra, Endang Sri Wahjuni
85. Relationship between Self-Care for Fluid Limitation and Interdialytic Weight Gain among Patients
with Hemodialysis at Ratu Zalecha Hospital, Martapura ...............................................................................437
Agus Rachmadi, Ita Ratnasari, Nursalam, Arief Wibowo
86. E�ect of Preoperative Biofeedback on Anal Continence After Fistula in Ano Surgery ................................442
Ahmed Farag, Hany M.S. Mikhail, Ahmed S. Khalifa, Mohamed T. Mostafa, Abdrabou N. Mashhour
87. Relation between Human Epididymis Protein 4 and Endometrial Pathology in Women with
Postmenopausal Bleeding ...............................................................................................................................447
Ahmed L. Aboul Nasr, Ghada A. Abdel Moety, Mostafa S. Salem, Marwa M. Elsharkawy, Nada
Kamal, Ahmed M. Maged
88. Evaluation of Eye Relaxation to Decrease Eye Strain in PT Japfa Comfeed Indonesia Unit Sragen ............453
Aisy Rahmania, Noeroel Widajati, Abdul Rohim Tualeka
89. E�ectiveness of Dorsata Honey Suplement on Interleukin-3 Levels in Breast Cancer Patients Who
Underwent Chemotherapy ..............................................................................................................................457
Aji Kurniawan, Daniel Sampepajung, Salman Ardy Syamsu, Prihantono Prihantono
90. E�ect of Blood Sampling Method During a Mating Time in Male Camels (Dromedary Camels)................463
Alaakamil Abdulla, Ali Habeeb Jaber AL‑bdeery, Basim Hameed Abed Ali
91. Hyaluronidase Versus Magnesium Sulphate as Adjuvants to Bupivacaine in Ultrasound Guided
Supraclavicular Brachial Plexus Block in Upper Limb Surgeries..................................................................469
Amany K abo Elhusein, Mamdouh Hassan, Nagat A. Ali
92. In�uence of Social Cultural Capital and Marketing on Skin Whitening Products Use among Higher
Education Female Students in the Northeast of Thailand ..............................................................................476
Anawat Phutongnak, Wongsa Laohasiriwong, Kittipong Sornlorm
93. Knowledge Management Based Performance Improvement on Certi�ed Health Workers in Health
Center of South Sulawesi ...............................................................................................................................482
Andi Mansur Sulolipu, Ridwan Amiruddin, Sukri Palutturi, Ridwan M. Thaha, Arsunan A.A.
94. Determinants that In�uence Relationship between Motivation and Job Satisfaction of Health Workers
at Primary Health Care in Indonesia ...............................................................................................................486
Armedy Ronny Hasugian, Jaslis Ilyas, Besral, Adang Bachtiar
95. Risk Factors for Obesity in Patients with Hypertension .................................................................................492
Aylinda Wahyuni Putri, Ratu Ayu Dewi Sartika
96. The Role of Social Support on Coping Stress in Type-2 Diabetes Mellitus Patients with Gangrene
Complications .................................................................................................................................................498
Ayu�Aisah��uraidah,�Arif�Nur�Muhammad�Ansori,� Suhailah�Haya�a,� Ilham�Nur�Al�an,� Suryanto,�
Nurul Hartini
VIII97. The Relationship of Work Instructions Compliance with Safe Behavior of Production Part Workers in
PT X ................................................................................................................................................................502
Ayu Prima Kartika, Windi Wulandari, Noeroel Widajati, Abdul Rohim Tualeka
98. The Relationship of Age and Work Period with Hearing Disorders on Workers Which are Exposed
to Noise Above Threshold Limit Value of Loom Part Weaving Ajl Department in Pt Bintang Asahi
Tekstil Industry ...............................................................................................................................................507
Bella�Oktavia,�Re�ania�Asy�radayati,�Abdul�Rohim�Tualeka
99. Health Literacyon Weighing Control and Use of Weight Loss Products among Working-age Women
in the Northeast of Thailand ...........................................................................................................................512
Chalee Yaworn, Wongsa Laohasiriwong, Kittipong Sornlorm
100. Awareness Regarding Heart Diseases among Middle Aged Adults in a Rural Area of Rupandehi District .517
Chanda Sah, Priyanka Gyawali
101. Correlation of Osteocalcin Urine Levels with Bone Mass Density in Menopause Women in H. Adam
Malik General Hospital Medan ......................................................................................................................521
Cherry Kumalasari,�M��Fidel�Ganis�Siregar,�Deri�Edianto,�Christo�el�L��Tobing,�M��Fahdhy,�Cut�
Adeya Adella
102. Bene�t of Thai Hermit Exercise on MCI Patients�: A Randomized Controlled Trial ...................................527
Chomlak Kongart, Yuttachai Likitjaroen, Surasak Taneepanichskul, PhD
103. Relationship of Individual Characteristics and Noise Intensity with Subjective Hearing Loss to
Workers at Pt. X .............................................................................................................................................534
Cut Suci Almadiana T., Sumihardi, Abdul Rohim Tualeka
104. The Role of Matrix Metalloproteinase-9 (MMP-9) and Tissue Inhibitor Metalloproteinase-1 (TIMP-1)
Level in Dengue Hemorrhagic Fever .............................................................................................................539
Dasril Daud, Nina Cicci Hasnani, Husein Albar
105. Ethanol Extract with Black Cumin (Nigella Sativa) Against sFlt-1 Level and VEGF Serum on
Laboratory Mice with Preeclampsia ...............................................................................................................544
Deasy Irawati, Hidayat Suyuti, Titi Maharrani, Fitriah, Ani Media Harrumi, Suryaningsih, Nursalam
106. E�ect of Nutritional Status, Hemoglobin Levels and Psychosocial Emotional Behavior with Cognitive
Function of Female Teenager .........................................................................................................................550
Diana Septaria Abidin, Roedi Irawan, Windhu Purnomo
107. Life Experience of Adolescents with Thalassemia: A Qualitative Research with Phenomenological
Approach ........................................................................................................................................................555
Dini Mariani, Sri Mulatsih, Fitri Haryanti, Sutaryo
108. The E�ect of Metabolic Syndrome on Systolic Function of Left Ventricle Using Echocardiographic
Examination ....................................................................................................................................................560
Doaa H. EL‑Farook, Hatem A. Sarhan, Manal M. Mohamed, Ahmed EL‑Barbary, Khaled A. Khaled
109. The Role of Mean Arterial Pressure (MAP) Roll Over Test (ROT) and Body Mass Index (BMI) in
Preeclampsia Screening in Indonesia .............................................................................................................566
Dwi Putri Rahayu Tampubolon, Lilik Herawati, Nursalam, Ernawati
IX110. Strategic Contribution of Health Services in the Indonesia-Malaysia Border to The National Resilience:
Analysis of Implementation in the West Kalimantan Province .....................................................................570
Dwi Rachmatullah, Dumilah Ayuningtyas, Raden Roro Mega Utami
111. Survival Analysis of Chronic Kidney Failure with a History of Degenerative Disease ................................575
Efri Tri Ardianto, Alinea Dwi Elisanti
112. Capital Knowledge Concept: Accounting Behavior and Health Management in Indonesia..........................581
Entar Sutisman, Bambang Tjahjadi, Hamidah
113. Early-Onset Neonatal Sepsis in Low-Birth-Weight and Birth-Asphyxia Infants at Haji Hospital
Surabaya, Indonesia ........................................................................................................................................586
Euvanggelia Dwilda Ferdinandus, Berliana Devianti Putri
114. Humanoid Robot Integration in Rehabilitation of Musculoskeletal Conditions ............................................591
Fayz S. Al‑Shahry, Rayan F. Al‑Shehri
115. Does Give Malnourished Pregnant Mothers with Supplementary Feeding Biscuit Can a�ect Pregnancy
Outcomes? ......................................................................................................................................................597
Henrick, Andi Imam Arundhana Thahir, Khartini Kaluku, Elsye Theresia, Saifuddin Sirajuddin, Veni
Hadju, Abdul Razak Thaha
116. Heavy Metals Concentration and Biochemical Parameters in the Blood and Nails of Industrial Workers ...602
Kameran Sh. Husien, Mohsin O. Mohammed, Tamara N. Ahmed
117. Impact of Workplace Violence Educational Program on Self Con�dence for Nursing Sta� Working
in Psychiatric Hospital ....................................................................................................................................607
Mohga Fathy Abd Elmoteleb Ali Hamza, Afaf Abd Elhamed Abd Elrahman
118. The Association of Glutathion Peroxydase-1 Serum and Sensorineural Hearing Lossin MDR TB
Patients with Kanamycin Therapy ..................................................................................................................612
Ratna Anggraeni, Arif Darmawan, Febri Wisudawan F.
119. Post-Traumatic Growth with Police O�cer: System Review (Focused on Korean and Foreign Studies) ....618
Seung Woo Han
120. HIV Stigma among Clinical Medical Students in East Java, Indonesia .........................................................623
Firas�Farisi�Alka�,�Adila�Tau�k�Syamlan,��resstisa�Gifta�Axelia,�Jovian��hillip�Swatan,�Sulistiawati
121. E�ectiveness of Falls Prevention Education on its Prevention Behavior among Older Adults: A
Systematic Review .........................................................................................................................................629
Goh Jing Wen, Devinder Kaur Ajit Singh, Suzana Shahar
122. Development of “Young Planning Clinic” Program as a Prevention Early in Adolescent Attitude in
Martapura River Areas ...................................................................................................................................635
Atikah Rahayu, Fauzie Rahman, Fahrini Yulidasari, Meitria Syahadatina N, Dian Rosadi, Nur Laily,
Hadianor.
123. Chipping Resistance of Nanosilica Treated Zirconia Cores Veneerd with Porcelain after Thermocycling
and Cycling Loading ......................................................................................................................................640
Hanaa F Mahmoud, Yaser F Gomaa, A Nour A Habib
X124. Assessment of Fracture Force of CAD-CAM-fabricated Occlusal Veneer Restorations with Di�erent
Thicknesses .....................................................................................................................................................646
Hanaa Saber Rabeae, Cherif Adel Mohsen, Shams Waaz Amgad
125. The Analysis of the Dynamics of the Willingness-to-Pay Indicator for the Use of Innovative
Technologies in Healthcare Calculated on the Basis of the Purchasing Power Parity of the Population
in the Post-Soviet Countries ...........................................................................................................................652
Hanna��an�lova,�Alla�Nemchenko,�Liusine�Simonian,�Oleg�Gerush,�Natalia�Bogdan,�Oksana�Tsurikova
126. Molecular detection of C5a Peptidase (scpB) Gene in Group B Streptococcus Isolated from Pregnant
Women and the Correspondence with Adverse Pregnancy Outcome ............................................................659
Hassan Saad Sakap, Jabbar S. Hassan, Sahar Hisham Abdul Razak
127. Role of MnSODVal16Ala Gene Polymorphism in Changing the Level of Serum Metals in Workers
Exposed to Heavy Mmetals in Al-Nasiriyah City ..........................................................................................665
Hayder Hussein Jalood, Afrah Abid Maktoof, Hassan R. Al‑Rekaby
128. Relative Hypoxia in Immunized Mice Spleen Macrophages as Indicated by Hypoxia Inducible
Factors, Cytoglobin and Peroxisome Proliferator Activated Receptor Gamma Coactivator (PGC)-1� ........671
Hijrah Asikin, Ninik Mudjihartini, Sri Widia A. Jusman, Mohamad Sadikin, Sarifuddin Anwar
129. The Emerging Risk of Interaction Between Complementary Alternative Medicines and Cardiovascular
Medicines ........................................................................................................................................................676
Huda S. Husni
130. E�ect of Exercises Using a Pressing Tool on Some Biochemical and Skilled Variables of Tennis Players .682
Hussein�Ali�Hussein�Al�Ku�
131. Evaluation of Angiopoietin One and Angiopoietin Two with Missed Abortion ...........................................686
Hussien Saeed Masood, Sami Akreem Zbaar, Bushra Mustafa Mohamed
132. Predictive Value of Toprs Score in Outcome of Pediatric Patient in Emergency Installation .......................692
Idham Jaya Ganda, Fitriya Idrus, Dasril Daud
133. Cellular Phone and Laptop Radiation E�ects on Subjective Complaints in Informatics Students ................697
Isna Qadrijati, Haris Setyawan, Seviana Rinawati, Tutug Bolet Atmojo, Rizka Andhasari Santoso,
Akbar Fadilah, Realita Sari
134. Comparing the E�ectiveness of Video-Assisted Teaching and Simulation on Nurses� Knowledge in
Performing Cardiopulmonary Resuscitation ..................................................................................................702
Jatim Sugiyanto, Karyono Mintaroem, Titin Andri Wihastuti
135. Association of Exon Deletion of MXI1 Gene with Cervical Abnormalities and Cancers Incidence in
Some Iraqi Married Women ...........................................................................................................................707
136. Curcumin and 6-Shogaol Increase Hemoglobin F Levels by Inhibiting Expression of STAT3 mRNA
Gene in K562 Line Cell ..................................................................................................................................712
Joko Setyono, Ahmad Hamim Sadewa, Edy Meiyanto, Mustofa.Mustofa
137. Introduction of Probiotic Type of Yogurt for the Treatment of Dysbiosis of Patients with
Lymphogranulomatosis Under Poly Chemotherapy of Beacopp-II Protocol ................................................718
Kaliberdenko V.B., Kuznetsov E.S., Morozova M.N., Malev A.L., Zakharova A.N., Shanmugaraj K.,
XIBalasundaram K.
138. In�uence of Mental Health and Social Relationships on Quality of Life among Myanmar Migrant
Workers in the South of Thailand ...................................................................................................................721
Kanit Hnuploy, Wongsa Laohasiriwong, Kittipong Sornlorm, ThitimaNutrawong
139. Lumbosacral MRI Findings in Chronic Lower Back Pain .............................................................................727
Kermanj Ismail Bakr, Israa Mohammed Sadiq
140. Joint E�ect Obesity and Oral Contraceptive Use towards Hypertension among Women in Thirteen
Provinces in Indonesia ....................................................................................................................................733
Kuuni Ulfah Naila El Muna, Helda
141. Tithonia Diversifolia vs Catechin: Role in Regulating Blood Glucose, Malondialdehyd, and Super
Oxide Dismutase Level on Rat Induced Diabetes Mellitus and High-Fat Diet ..............................................739
Lailatul Muniroh, Rondius Solfaine, Indra Rahmawati
142. Comparison between the Antioxidant Activity of Volatile Oil and Hydrosol in Eucalyptus
Camaldulensis (Young and Adult) Leaves .....................................................................................................745
Lamiaa A. Gharb
143. Selfcare Behaviour of the Diabetic Patients in a Primary Health Center in Bali ...........................................750
Made Mahaguna Putra, Kusnanto, Candra Panji Asmoro, Tintin Sukartini, Tjahja Bintoro, Ni Made
Dwi Yunica Astriani, Putu Indah Sintya Dewi
144. Cut o� Point of Insulin-Like Growth Factor-I (IGF-1) for Prediction of Child Stunting ..............................755
Masrul, Doddy Izwardy, Ricvan Dana Nindrea, Ikhwan Resmala Sudji, Idral Purnakarya
145. E�ect of Generative Learning Strategy with Visual Technologies in Learning Some Basic Skills and
Motor Abilities for 5-6-Years Kindergarten Children ....................................................................................761
Mayadah Khalid Jasim
146. The E�ect of Self-Regulated Learning Strategy in Motor Hyperactivity and Learning the Performance
of Skill of Jump Shot in Basketball for Freshmen High School Students ......................................................766
Mayadah Khalid Jasim, Shaymaa Jasim Mohammed
147. In�uence Organizational Citizenship Behavior (OCB) on Performance Nurses Public Health Centre
in the District Tuban .......................................................................................................................................771
Miftahul Munir
148. Combined Exercise E�ects on Lipid Pro�les in Hypertensive Patients .........................................................775
Mitiku Daimo, Soumitra Mondal, Mahmud Abdulkader, Dhamodharan Mathivanan
149. Ego State Therapy (EST) and Systemic Desensitization (SD) to Reduce School Refusal among Senior
High School Students .....................................................................................................................................781
Mochamad Nursalim, Nur Hidayah, Adi Atmoko, Carolina L. Radjah
150. Implant Materials Used for Orbital Floor Reconstruction ..............................................................................787
Mohamed Esmail Khalil, Mohamed Farag Khalil, Raafat Mohyeldeen Abdelrahman, Ahmed
Mohamed Kamal Elshafei, Tamer Ismail Gawdat
151. Expression of Amylin and Preptinin Iraqi Patients with Type 2 Diabetes Mellitus .......................................793
XIIMohammed I. Hamzah, Israa A. Abdul Kareem, Mohammed Albayati
152. Evaluate The Correlation Between Antioxidant Capacity And Interferon � Level With The Disease
Activity Of Sle Patients In Iraqi Woman ........................................................................................................799
Mohammed�T��Alaan�y,�Jinan�M�J��Alsa�ar,�Ahmed�Abdul�Bari
153. Comparative E�ect of Mulligans Mobilisation Versus Stabilisation Exercise on Chronic Nonspeci�c
Low Back Pain: A Pilot Study ........................................................................................................................804
Mohan Kumar G., Jibi Paul, Sundaram M.S., Mahendranath P.
154. Factors Associated with Work Fatigue in Workers of the Nipah Building Construction Project Makassar..810
Muh. Arfandi Setiawan, Awaluddin, Andi Wahyuni, Abdul Rohim Tualeka
155. Quality Evaluation of Health Services at Community Health Centers: through Accreditation Surveys
in Indonesia .....................................................................................................................................................815
Muhammad Tahir, Ridwan Amiruddin, Sukri Palutturi, Fridawaty Rivai, Lalu Muhammad Saleh,
Owildan Wisudawan B
156. Hypoglicemic and Antioxidant Activity of Yellow Pumpkin (Curcubitamoschata) in Diabetic Rats ...........821
Muji Rahayu, Menik Kasiyati, Atik Martsiningsih, Budi Setiawan, Furaida Khasanah
157. Association of Diabetes Mellitus and Estrogen Hormone Levels with Vaginal Candidiasis.........................826
Netti�Suharti,�Almudri,�Ricvan�Dana�Nindrea,�Sil�na�Indriani
158. P24 Antigen Quanti�cation of Indonesian Patients Infected with HIV-1 CRF01_AE ..................................831
Ni�Luh�Ayu�Megasari,�Devi�Okta�ani,�Elsa�Fitriana,�Nasronudin,,�Soetjipto,
159. E�ect of Black Seed (Nigella Sativa) Extract on Release of Some Minerals from Human Enamel: An
in Vitro Study .................................................................................................................................................836
Nibal Mohammed Hoobi, Raya R. Al‑Dafaai, Baydaa Hussain
160. Ef�cacy of Catharanthus Roseus Extract Against Dengue Virus Type 2 Infection in Vitro .........................841
Noor��arina�Abd��ahab,�Norefrina�Sha�na��Md��Nor,�Na�lina�Ibrahim
161. Psychometric Evaluation of a Feedback Conception Scale: Building Positive Feedback Practises of
Charge Nurses in Public Hospitals .................................................................................................................845
Nor Hasnida Che Md Ghazali*, Mohd Nazir Md Zabit, Mahizer Hamzah
162. Factors Associated with Hypertension among Adults in West Java, Indonesia .............................................850
Nurul Wahyu Wadarsih, Ratu Ayu Dewi Sartika
163. Correlation of Interleukin-6 with Serum Estradiol Mean Levels in Menopause Women at Rsup H
Adam Malik Medan ........................................................................................................................................856
Nutrisia Latjindung, M. Fidel Ganis Siregar, Hanudse Hartono, Sarma N. Lumbanraja, Deri Edianto,
Iman�Helmi�E�endi
164. High Bride Price as Determinant of Marital Stability among Akwa-Ibom People in Surulere Area,
Lagos State, Nigeria .......................................................................................................................................862
Oniyangi, Shuaib Olanrewaju, Jamiu Abdul Qudus Tosin & Owo, Blessing, Umar Ibrahim Babangida
& Ahmad Makama Getso, Sindama Helen
165. Psychosomatic Impact of Social Networking Sites on Society and its Subtle But Real Consequences ........867
XIIIAbhimanyu Chopra, J.K. Mittal
166. Detection of Extended-Spectrum-Beta-Lactamase (ESBL) Producing Escherichia Coli in Meat
Chicken from Traditional Market in Surabaya, East Java, Indonesia ............................................................872
Dhandy�Koesoemo��ardhana,�Mustofa�Helmi�E�endi,�Nenny�Harijani,�Hong‑Kean�Ooi
167. Health Problems of Prospective Brides in Rural Area of East Java, Indonesia .............................................877
Nunik Puspitasari, Sri Sumarmi, Yuly Sulistyorini
168. Cytotoxic Activity and Selectivity Index of Solanum Torvum Fruit on T47D Breast ...................................883
Nunuk Helilusiatiningsih, Yunianta, Harijono, Simon Bambang Wijanarko
169. The Relationship between Father Involvement with Growth and Social-Emotional Development in
Preschool Children .........................................................................................................................................889
Nur Hijrah Tiala, Fitri Haryanti, Akhmadi
170. Auditory evaluation with Pure Tone Audiometry and DPOAE in Kanamycin Treatment of Multidrug-
Resistant Tuberculosis ....................................................................................................................................896
Nyilo Purnami, Aditya Brahmono, Bakti Surarso
171. Assessment of Coronary Heart Disease Risk among Diabetes Mellitus Survivor in Community Health
Center Purwosari Indonesia ............................................................................................................................901
Okti Sri Purwanti Agus Sudaryanto, Ahmad Faris Muntaha, Agus Sudaryanto
172. E�ectiveness of Providing Self-Management Education to Deal With Emesis Gravidarum on
Decreasing Nausea Vomiting Pregnancy (NVP) at Private Practice Midwives Puskesmas IV Denpasar
Selatan Work Area ..........................................................................................................................................906
Ni Nyoman Deni Witari, Ni Made Dewianti
173. The E�ectiveness of Progressive Muscle Relaxation with Benson Relaxation on the Sleep Quality in
Hemodialysis Patients .....................................................................................................................................911
Theresia Uli Porman Purba, Ridha Dharmajaya, Cholina Trisa Siregar
174. Characteristics of Patients with Diabetic Foot Ulcers and Predictors of Surgical Intervention in Basrah,
Southern Iraq ..................................................................................................................................................916
Abdulhussein�K��Mar�oq,�Ra�d�Abduljabbar�Mohammed,�Omran�S��Habib
175. Low CD4 Level Increased the Risk of Cognitive Impairment in the HIV Patient .........................................922
Nurul Azizah, Abdulloh Machin, Muhammad Hamdan
176. Antibacterial E�ect of the Combination of Probiotic Milk and Calliandra Honey against Streptococcus
Mutans that Causes Tooth Cavities ................................................................................................................927
Uswatun Chasanah, Isnaeni, Nuzul Wahyuning Dyah
177. Reproductive Health Behavior of Street Youth Guided by Karya Putra Indonesia Mandiri Foundation
in Central Jakarta Region ...............................................................................................................................932
Prihayati, Hansrizka Raisna, Ridwan Amiruddin, Owildan Wisudawan B.
178. Trend of Malaria Cases in Maluku Province 2012-2016 ...............................................................................936
Prisilia Oktaviyani, Budi Hartono, Ranti Ekasari
179. A Qualitative Study: Perceptions of Premarital Sexual Behavior Among Teenage Girls .............................944
XIVMia Fatma Ekasari, Eros Siti Suryati, Raden Siti Maryam, Ahmad Jubaedi, Rosidawati, Tien Hartini,
Santun Setiawati
180. Hazard and Risk Analysis by Implementing Hiradc Method in the Laboratory of Medical-Surgical at
Faculty of Nursing Universitas Airlangga ......................................................................................................949
Radhia Maya R.P., DaniNasirul H., PutriAyuni Alayyannur, Tjipto Suwandi, Rizky Agung Firnando
181. A Three-Years Survival Rates of Chronic Myeloid Leukemia Patients with Targeted Therapy ...................955
Rani Silondae, Tutik Harjianti, Sahyuddin Saleh, Syakib Bakri, A. Makbul Aman, Hasyim Kasim,
Haerani Rasyid
182. The Relation between Bullying Workplace, Organizational Support, and Work Engagement as
Perceived by Sta� Nurses ...............................................................................................................................961
Rasha Mohamed Nagib Ali, Ebtsam Ahmed Mohamed
183. The E�ect of Alkaloid Extract of Teucrium Polium L. Against Some Pathogenic Bacteria of Urinary
Tracts and on Pyelonephritis Induced in Rats ................................................................................................969
Rawa’a A. Kushaish, Bushra A.M. AL‑Salem, Mouayed A. Hussein
184. A Study of Complications of Infants of Diabetic Mothers in Babylon Teaching Hospital for Maternity
and Pediatrics ..................................................................................................................................................974
Rebee Mohsin Al‑Ithary
185. The Relationship between Obesity and Dyslipidemia in Adolescents ...........................................................980
Ria Qadariah Arief, Ridwan Amiruddin, Syamsiah Russeng, Citra Kesumasari, Nurhaedar Jafar,
Ummu Salamah, Nugrahaeni
186. The Individual Factor and the Quality of Building�s Physical Environment in Correlation with the
Occurrence of Sick Building Syndrome (SBS) on Employees of PT. Telkom Jember .................................984
Rizki Adi Sulistyanto, Ragil Ismi Hartanti, Prehatin Trirahayu Ningrum, Abdul Rohim Tualeka
187. Public Knowledge on Over the Counter Analgesics at Private Pharmacy Store in Makassar City
Indonesia .........................................................................................................................................................989
Rizqi Nur Azizah, Hendra Herman,
188. E�ect of Di�erent Levels of Coriandrum Sativum and Piper Nigrum and their Interaction on
Production, Biochemical Parameter, Liver Enzymes, TSH and Growth Hormone for Broiler Chickens .....993
S.G. Hussein, H.Q. Baker
189. Parental Style and its Relation to Adolescents� Self-Concept and Depression ..............................................999
Safaa Mohammed Zaki, Manal Hassan Abo Elmagd, Nagat Farouk Abo Elwafa
190. Diagnostic Study and Some Pathological Aspects of Parasites Associated with Appendicitis in Al-
Najaf Al-Ashraf Governorate .......................................................................................................................1007
Sahira Ayed A. Al‑Musawi
191. Antibacterial Activity of Zinc Oxide Nanoparticles on the Growth of Enterococcus Feacales, Candida
and Total Root Canal Microbiota (In Vitro Study) ......................................................................................1011
Salah A. Hadi, Abbas S. Al‑Mizraqchi
192. Assessment of Exam-related Anxiety among the Students of the High Healthy Vocations Institute at
XVMedical City .................................................................................................................................................1017
Sameer Allawi Khalaf, Meaad Kareem Halboos
193. Urinary Intestinal Fatty Acid Binding Protein “IFABP” as a Marker for Gut Maturation in Preterm
Babies ...........................................................................................................................................................1023
Samir Tamer Abd‑Allah, Hanan Mostafa Kamel, Madeha Abd‑Allah Sayed, Yossra Samir Fadle
194. Associations between TNF-� and Interleukin-18 and ADIPOQ Gene Polymorphisms in Iraqi Obese
Women Patients with Polycystic Ovary Syndrome ......................................................................................1028
Sarah Ibrahim Hashoosh, Asmaa A. Hussien, Salah Al Chalabi
195. C2 Lateral Mass Vertebrae Anthropometry for Evaluating C2 Straight Lateral Mass Screw Fixation .......1034
Sarrah�Dwiananda�Mayasa�ra,�Joni�Susanto,�Eko�Agus�Subagio
196. Correlation between Health Locus of Control with Intention to Perform Cataract Surgery in the Area
of Public Health Center of Tempurejo Jember .............................................................................................1040
Siswoyo,�Baskoro�Setioputro,�Kushariyadi,�Iqbal�Luth��Nauri
197. Implementation of Tender Loving Care-Based Growth and Development Monitoring by Health Cadres..1046
Siti Asiyah, Dewi Retno Suminar, Ahsan, Shrimarti Rukmini Devy, Moersintowarti B. Narendra
198. Regional Health Care: Does Give Bene�ts for Poor Communities? ............................................................1051
Siti Nuraini, Riski Isminar Ardianti, Deddy Kurniawansyah
199. Measures of Modern Society to Limit the Prevalence of Sexually Transmitted Infections .........................1056
Sizov A.A., Pashina I.V., Lischuk N.G., Alferova M.E., Lyaskovets A.V., Shahbazov R.F., Andreeva N.A.
200. E�ect of Non-Computerized Cognitive Remediation and Risperidone to Improve Disability Function
in Schizophrenia ...........................................................................................................................................1061
Sonny T. Lisal, Saidah Syamsuddin, Anisa
201. The E�ect of Olanzapine on the Improvement of the Clinical Symptom of Schizophrenia ........................1067
Sonny T. Lisal, Saidah Syamsuddin, Balgis
202. Study of Some Virulence Factors of Candida Albicans Causing Intestinal Infection ..................................1073
Sozan Khaled Kadhum
203. Correlation between Protein Intake, Parity and Miscarriage History Anemic Pregnant Women in
Sukoharjo Regency, Indonesia with Low Birth Weight Incidence: A Case Control Study .........................1079
Su�a�Fitriani,�Eti��oncorini��amungkasari,�Suminah
204. Changes in Community Behavior and Keeping the Quality of Drinking Water Based Ranas Models .......1084
Sugeng Mashudi, Ah. Yusuf, Rika Subarniati Triyoga
205. Breast Cancer and Hormonal Level Changes ...............................................................................................1090
Suhad Kahdum Ali
206. Socio-demographic Characteristics and Caregiver�s Quality of Life Associated with Suspected
Developmental Delay among Early Childhood in Northeast of Thailand ....................................................1096
Supattra Boonjeam, Rajda Chaichit, Benja Muktabhant, Suwit Udompanich
207. The In�uence of ACTN3 Gene Polymorphism on VO2max and Sprint Speed Based on Sprint Interval
XVITraining Intervention ....................................................................................................................................1102
Susiana Candrawati, Nur Signa Aini Gumilas, Dyah Ajeng Permatahani, Muhammad Fadhil Wasi
Pradipta, Lantip Rujito
208. Predisposing Factors to Risk of Low Birth Weight in Premature Baby in Bengkulu Indonesia .................1108
Susilo Damarini, Hadi Pratomo, Helda, Besral
209. Education and Knowledge Level Analysis of the Teachers Regarding Dental Education Program in
Primary Schools ............................................................................................................................................1113
Taufan Bramantoro, Titiek Berniyanti, Retno Palupi, Ninuk Hariyani, Fatan Fakihardi, Aulia
Ramadhani, Sarah Fitria Romadhoni
210. Revised Trauma Score (Rts) as Outcome Predictor of Head Injury Patients ...............................................1118
Tengku Isni Yuli Lestari Putri, Ahsan, Dhelya Widasmara
211. The Relationship between Obesity and Fasting Blood Glucose Levels in High School Teachers ..............1124
Tri Setyawati, Muhammad Ikbal, Fenny Nur Afny, Muhammad Nasir,
212. A Case Study of the Health Adaptation of Former Schizophrenics in Communicating with the Bugis
Makassar Community in the South Sulawesi Province ................................................................................1129
Tuti�Bah�arti,�Arianto,�Muhammad�Harun�Achmad
213. Risk Factors Associated with HIV Infection among Male to Transvestites in Five Cities in Indonesia
in 2015 ..........................................................................................................................................................1135
Udin Komarudin, Tri Yunis Miko Wahyono
214. Shift Working Relationship with Blood Pressure in Excess Noise Workers Exposed NAB Spinning in
the Department of the Winding Pt Star Asahi Textile Industry ...................................................................1141
Vivi Budiarti, Tina Rosa Rachmawati, Abdul Rohim Tualeka
215. Is Osteopontine of Value in Diagnosis of Knee Osteoarthritis? ...................................................................1147
Walaa F. Mohammed, Faten Ismail Mohamed, Gihan M. Ahmd, Rasha A. Abdelmagied, Aliaa M.
Mounir, Mustafa Abdel‑ Kader
216. A Prospective Study of E�ectiveness of Pre-release Intensive Program for Prisoners in Thailand ............1150
Wanna Pajumpa, Manop Kanato, Kittima Momen
217. Factors Associated with Behavior Usage of Respiratory Protective Equipment among Sugarcane
Factory Workers in Northeast of Thailand ...................................................................................................1156
Wipada Panakobkit, Pornpun Sakunkoo
218. Re-evaluation of Psoriatic Patients with Metabolic Syndrome: A Case Control Study Searching for
the Highly Prevalent Criteria ........................................................................................................................1162
Wisam Majeed Kattoof
219. E�ect of Dragon Fruit (Hylocereus Polyrhizus) Peel Extract on Collagen Fiber Density of Rat Socket
Healing ..........................................................................................................................................................1168
Wisnu Setyari Juliastuti, Hendrik Setia Budi, Christiana Ayu Maharani
220. Guided Group Investigation, Sca�olding Task Questions and Self-E�cacy in Learning to Solve
Social Problems in Inclusive Schools ...........................................................................................................1173
XVIIWiwik Widajati, Punaji Setyosari, I Nyoman S. Degeng, Sumarmi, Mustaji
221. Perceptions of Teachers, Parents and Adolescents about HPV, Cervical Cancer and HPV Vaccination ....1179
222. Occupational History as a Predictor of Cognitive Ability in the Elderly .....................................................1185
Yudhiakuari Sincihu, Felicia Sinjaya, Edith Maria Djaputra
223. The E�ect Of Employment Time with the Low Back Pain Disorders on Workers in the ‘X� Carpet
Fitting Work Unit Pasuruan ..........................................................................................................................1190
Zikri Fathur Rahman, Nur Lailatul Masruroh, Noeroel Widajati, Abdul Rohim Tualeka
224. Lived Body Principle of a Nurse�s Experience in Emergency Treatment at Remote Area Kokonao,
Papua, Indonesia ...........................................................................................................................................1193
�ulki�i,�Indah��inarni,�Asti�Melani�Astari
225. Biliary Atresia Outcome in Egypt: A Descriptive Study .............................................................................1198
Omar N. Abdelhakeem, Gamal H. Eltagy, Alaa A. El. Sayed, M.M. Khedr
226. Manipulative Movement Based on Information Technology Games for School Children Aged 10-12
Years .............................................................................................................................................................1202
Nevi Hardika, Moch. Asmawi, James Tangkudung, Firmansyah Dlis, Abdul Sukur, Widiastuti, M.E. Winarno
227. The In�uence of Job Stressor on Organizational Loyalty and Intention to Quit among Health Care Sta� .1209
Mohammad Saipol Mohd Sukor, Siti Aisyah Panatik, Wan Mohd Azam Wan Mohd Yunus
228. Emotional Intelligence and Con�ict Management Style among Sta� in a Bank .........................................1214
Maisarah Mohd, Halimah Mohd Yusof
229. Trend on Drink Drive and Road Accident Across Asian Region: A Review Study ....................................1219
Siti Hawa Harith, Norashikin Mahmud
230. Obesity and Job Performance among Teachers in Malaysia ........................................................................1227
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XIXShinta TD Nawangwulan, Achmad Hufad, Jajat S. Ardiwinata, Iip Saripah, Dadang Yunus L.
922��Indian Journal of Public Health Research & Development, January 2020, Vol. 11, No. 01
Low CD4 Level Increased the Risk of Cognitive Impairment in the HIV Patient
Nurul Azizah1, Abdulloh Machin1, Muhammad Hamdan1
1Faculty of Medicine, University of Airlangga, Surabaya, Indonesia, Department of Neurology,
Dr. Soetomo General Hospital, Surabaya, Indonesia
Abstract
Background: HIV infection leads to neurological damage that results in cognitive and behavioural
impairment called HIV-associated neurocognitive disorder (HAND). There are several factors associated
with HAND which include the CD4 count. Patients who present with the CD4 level lower than 200 cells/
mm3 are considered very vulnerable of experiencing neurological complications such as HAND.
Objective: To investigate the association between CD4 level and cognitive impairment evaluated using
MoCA-INA among HIV patients.
Materials and Method: This cross-sectional study involves 72 consecutive patients with HIV (Human
Immunode�ciency Virus) infection from the Infecion Ward of Soetomo General Hospital Indonesia. All
participating patients was measured its cognitive impairment through MoCA-INA score. Blood samples
were collected for CD4 evaluation. Statistics were evaluated with SPSS 25.0.
Results: The research participant consisted of 43 (59.7%) male and 29 (40.3%) female with mean age of
38.22 ± 9.159, CD4 level of 447.4 ± 247.48 and MoCA-INA score of 26.36 ± 2.770. Chi-Square analysis
showed a signi�cant di�erence (p-value of 0.023) in the cognitive function in the HIV patient with low
CD4 (CD4<200cell/mm3) compared tonormal CD4 (CD4�200 cell/mm3) with Odd Ratio of 4.900 (95% CI,
1.278–18.793).
Conclusions: Low CD4 level increase the risk of cognitive impairment assessed using MoCA-INA
scoring system. These suggested that HIV patient with low CD4 should have initial screening of cognitive
impairment.
Keywords: Cognitive,�Immunode�ciency,�Mental�Health,�MoCA-INA�
Corresponding Author:
Muhammad Hamdan
M.D, Neurologist, Department of Neurology, Faculty
of Medicine, University of Airlangga, Surabaya,
Indonesia- Mayjend Prof Moestopo Street no 47,
Surabaya, East Java, Indonesia
e-mail: [email protected]
Introduction
UNAIDS (Joint United Nations Programme on
HIV/AIDS) reported that the incidence of HIV infections
across the globe reached 36.7 cases at the end of 2015.
It has also been reported that there are approximately 5
million HIV cases around Asia.1 Department of Health
of the Republic of Indonesia reported the cumulative
number of HIV and Acquired� Immunode�ciency�
Syndrome (AIDS) cases from all 34 provinces and 407
districts/cities across the nation since the �rst time it was
discovered in 1987 up to March 2016 were 198,219 and
78,292 cases, respectively.2
HIV could lead to neurological damage that
results in cognitive and behavioral impairment called
AIDS Dementia Complex (ADC) or HIV-associated
neurocognitive disorder (HAND).3 HAND is one of the
most important HIV-related complications in this era of
antiretroviral (ARV) therapy. ARV combination therapy
Indian Journal of Public Health Research & Development, January 2020, Vol. 11, No. 01��923
using highly active antiretroviral therapy (HAART)
is found to substantially improve the neurocognitive
function and is attributed to a signi�cant decline in the
incidence of HAND. The prevalence of neurocognitive
disorders, however, is still beyond the expected number
that reaches over 50%. This is attributed to the fact that
in this era of HAART, there has been a shift on HAND�s
clinical presentation towards milder disease that results
in delayed diagnosis should the formal neurocognitive
and neuropsychological assessment not performed due
to subtle manifestation. The prevalence, incidence and
severity of HAND is increased along with the increased
population of HIV patients.4 Several factors are thought
to correlate with the occurrence of HAND and one of
which is the CD4 counts. The patients who present with
the CD4 level lower than 200 cells/mm3 are at a substantial
risk of developing neurological complications.4 The low
CD4 level can lead to decreased systemic immunity and
increased proliferation of HIV within the central nervous
system (CNS).6 Furthermore, a series of processes will
take place and lead to neural cell death and eventually
the cognitive impairment/HAND; however, the studies
investigating the association between CD4 counts and
HAND are still limited.
MoCA has been widely used in the assessment of
cognitive function. We chose MoCA as the instrument
for cognitive assessment in this study given the contents
of the questionnaire that cover various cognitive
domains, including executive function, visuospatial
function, attention and concentration, memory, language,
calculation and orientation.7 Indonesian version of
MoCA, also called MoCA-INA, has been developed
and validated in Indonesia and thus can be used as an
instrument for cognitive assessment in our population.
The objective of this study was to investigate the
association between CD4 counts and the occurrence
of cognitive impairment assessed using MoCA-INA
scoring system among HIV patients.
Materials and Method
Research Design: This retrospective study consisted
of patients with HIV infection from the Infection ward
of Dr. Soetomo General Hospital, Surabaya. Eligible
patients required to be � 18 years old and diagnosed with
HIV infection. Patient with depression, structural brain
lession or illiterate are excluded.
Cognitive Impairment Measurement: Cognitive
ability was measured by using Montreal Cognitive
Assessment-Indonesian Version (MoCA-INA) score.
All elligible patient requires to �ll the questionaire.
CD4 measurement: CD4 measurement was
done through blood sampling and analyzed using
�owcytometry.
Statistical Analyses: Statistical analyses were
performed using IBM SPSS Statistics 25.0. Data are
considered signi�cantly di�erent if p<0.05. Non-
parametric data were evaluated and compared using the
chi-quare test.
Findings:
Demography of HIV patients: The demographic
characteristics (age, gender, level of education, and
ethnicity) and the clinical characteristics (body mass
index, vascular risk factors, and CD4 counts) of the
study participants are shown in table 1 and 2.
Table 1: Characteristic of the study participant
Variables (N = 72) n (%) Mean SD
Gender
Male 43 (59.7)
Female 29 (40.3)
Age 38.22 ± 9.159
> 50 years 8 (11.1)
50 years 64 (88.9)
Years of education 12.35 ± 2.738
Level of education
Elementary school 1 (1.4)
Junior high school 15 (20.8)
Senior high school (and equivalents)
37 (51.4)
College/University degree 19 (26.4)
Ethnicity
Javanese 62 (86.1)
Madurese 4 (5.6)
Timor 2 (2.8)
Malay 1 (1.4)
Chinese 2 (2.8)
Ambonese 1 (1.4)
924��Indian Journal of Public Health Research & Development, January 2020, Vol. 11, No. 01
Table 2: Clinical Characteristics of Study Participants
Variables n (%) Mean SD
Body mass index 23.35 ± 4.854 (13.5-34.3)
Overweight - Obese 25 (34.7)
Underweight- Normal 47 (65.3)
Vascular risk factors
Yes 13 (18.1)
No 59 (81.9)
CD4 counts 447.4 ± 247.48 (5-1427)
< 200 11 (15.3)
200 61 (84.7)
MoCA-INA score 26.36 ± 2.770 (16-30)
< 26 18 (25)
26 54 (75)
The statistical analyses from the patient demography showed no signi�cant di�erences for all the confounding
factor, hence a multivariate analysis was not necessary. The results for this analyses are presented in table 3.
Table 3: Clinical Characteristics of the Study Participants
MoCA-INAp OR (95%CI)
Impaired (%) Normal (%)
Age
0.101 3.571
(0.791-16.123)
> 50 years 4 (22.2) 4 (7.4)
< 50 years 14 (77.8) 50 (92.6)
Gender
1.000 0.926
(0.311-2.759)
Female 7 (38.9) 22 (40.7)
Male 11 (61.1) 32 (59.3)
Level of Education
0.539 0.634
(0.198-2.026)
Elementary-high school 12 (66.7) 41 (75.9)
College/University degree 6 (33.3) 13 (24.1)
Body Mass Index
1.000 0.921
(0.298-2.845)
Overweight- obese 6 (33.3) 19 (35.2)
Underweight - Normal 12 (66.7) 35 (64.8)
Vascular Risk Factors
0.495 0.489
(0.097-2.450)
Yes 2 (11.1) 11 (20.4)
No 16 (88.9) 43 (79.6)
Comparison between CD4 criteria on the HIV patient with cognitive impairment and normal function showed
a signi�cant di�erences (p = 0.023) with an odds ratio of 4.900 (95% CI, 1.278 – 18.793). Sugessting that low CD4
may increase the risk of cognitive impairment by 4.9 times. The result can be seen on the table 4.
Table 4: Comparison between CD4 Group and Cognitive Impairment
MoCA-INAp OR (95%CI)
Impaired (%) Normal(%)
CD4 Counts
0.023 4.900
(1.278-18.793)< 200 6 (33.3) 5 (9.3)
200 12 (66.7) 49 (90.7)
Total 18 (100) 54 (100)
Indian Journal of Public Health Research & Development, January 2020, Vol. 11, No. 01��925
Discussion
This research showed that HIV patient with the CD4
counts of <200 cells/mm3 are at 4.9 times higher risk
of having impaired cognitive function based on MoCA-
INA scoring system compared toHIV patient with
CD4 counts of 200 cells/mm3. Similarly, previous
research also showed that CD4 level is a good predictor
for HAND (HIV-associated Neurocognitive Disorder)
which showed the p-value of 0.003 and odds ratio of
3.45 (95% CI, 1.51 – 7.91).8 Another study also reported
that the higher CD4 level is correlated with better
cognitive function among HIV-AIDS patients evaluated
using MoCA-INA (r = 0.347).9 This suggested that
HIV patient with low CD4 counts consistently showed
increased risk of cognitive impairment, which should be
screened properly.
The mechanism which responsible for the increased
risk of cognitive impairment in the patient with low CD4
count is not fully explored in this research. However,
we speculate that low CD4 level results in decreased
systemic immunity among HIV patients and predisposes
to the proliferation of the virus within the CNS.5 A
series of molecular processes will occur and result in
both direct and indirect cellular death of the nervous
system. The direct mechanism of cellular death involves
neurotoxic e�ects exerted by the viral protein released
from the infected monocytes and cause neural cell death
via direct interaction between the viral protein and the
neuron (gp120, Tat, and Vpr).10
On the other hand, the indirect cellular death
mechanisms involve neurotoxic processes from the
macrophages. The activated macrophages and microglial
cells (in response to HIV infection or exposure to the
viral particles) will secrete a number of mediators
which consist of arachidonic acid and quinolinate,
nitric oxide (NO), platelet activating factor, superoxide
anions, matrix metalloprotease, chemokines, and pro-
in�ammatory cytokines including tumour necrosis
factor (TNF). Subsequently, the cytokines and other
substances released during this process, will interfere
with neuro-protective function of the astrocytes (to
maintain the blood brain barrier integrity and glutamate
reuptake) as well ass increase the rates of apoptosis of
the astrocytes.10
In addition, neurotoxic processes induced by the
host factors, including secretion high amount of amino
acids such as glutamate (an excitatory neurotoxic
neurotransmitter at the very high level) and other
N-methyl-D-Aspartate (NMDA) receptor agonists
can create an excitotoxic environment that produces
excessive NMDAR activation. Consequently, the intra-
neuronal calcium concentration will reach the toxic
level and lead to production of free radicals, including
Reactive Oxygen Species (ROS) and NO as well as
cellular death. These three processes subsequently lead
to neural damage/cell death and eventually result in
cognitive impairment/HAND.10
Clinical implication of this study is that patients
with CD4 counts of <200 cells/mm3 needs a baseline
cognitive function assessment since their diagnosis
of HIV infection. In order to implement these results,
cohort studies are required to analyze the correlation
and regression between CD4 counts and cognitive
impairment among HIV patients.
Conclusion Patient with Low CD4 level of less
than200 cells/mm3 will have increased risk of cognitive
impairment assessed byMoCA-INA scoring system.
These suggested that the HIV patient with low CD4
should be screened for cognitive impairment to provide
early prevention and treatment.
Con�ict�of�Interest:�The authors declare no con�ict
of interest
Source of Funding: This research received no
external funding
Ethical Clearance: The research was conducted
in accordance with the Helsinki declaration of 1975
as revised in 2000. All participating patient has signed
written informed consent. The study protocol has been
approved by the local ethics committee. Data which
shows patient personal information was omitted.
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