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Waisman CenterUniversity of Wisconsin-Madison
To advance knowledge about human development,developmental disabilities, and neurodegenerative diseases
throughout the life span.
Mission
What is a “Developmental Disability”?
•Onset is prenatal or early in life•Affects a child’s development in
multiple and significant ways•Lasts indefinitely
Examples…
•Autism, Down syndrome, cerebral palsy,fragile X syndrome, epilepsy, other types ofintellectual disability (formerly calledmental retardation)
What is a “Neurodegenerative Disease”?
•Onset can be at any point in life•Affects a person’s life in multiple
and significant ways•Lasts indefinitely and often is
the cause of death
Examples…
•Parkinson’s Disease, ALS(Lou Gehrig’s disease),Alzheimer’s Disease,spinal cord injury
The Waisman Center’s Overarching Goal –to discover the 3 “C’s”
◘ Causes (genetic,environmental)
◘ Consequences -- for theindividual, the family, andsociety
◘ Cures and treatments
The 3 C’s: The Example of Autism
◘ Causes
- What is the cause of the rising prevalence of autism?- What is the role of genetics in causing autism?
◘ Consequences- What is the lifetime cost of care for a person with autism?- What are the consequences for the family?- How do people with autism differ in brain function and
structure from people without disabilities?
◘ Cures and treatments- What targeted medical treatments and educational services
reduce the severity of autism?
Precursor to the Waisman Center - 1963
UW Orthopedic Children’s Hospital
•Addition built in 1963 for theJoseph P. Kennedy, Jr. MemorialLabs, funded by a grant fromKennedy Foundation.
•Dr. Harry Waisman, Director
Dedication of the
Joseph P. Kennedy
Jr. Laboratories ─
November 20, 1963
•Director of research at theJoseph P. Kennedy, Jr.Memorial Laboratories
•Pediatrician, biochemist,pioneer in research onchildhood disability
•Advocated for testing of allnewborns for geneticdiseases
•Role model for us today
Who was Harry Waisman?
•A Presidential Panelrecommended creation ofmultidisciplinary centers focusedon intellectual disabilities atmajor universities.
Construction of the Waisman Center
•Waisman Center becomes oneof those centers, opening in1973.
Fifteen Centers in the U.S.
•a multidisciplinaryresearch center
and•a clinical, service,
and outreach center
◘ The Waisman Center is the only one that houses both –
•Both are needed to translate research resultsinto treatments –translational research
Carolyn “Biddy”Martin, ChancellorUniversity of Wisconsin-Madison
Schools and CollegesAg & Life SciencesEducationEngineeringHuman EcologyLetters and ScienceMedicine/Public HealthNursingPharmacyVeterinary Medicine
The Waisman Center in the UW-Madison
Martin Cadwallader, DeanGraduate School and VC for Research
Marsha Mailick Seltzer, DirectorWaisman Center
Waisman Center Facts
• 55 faculty members from 27departments at the UW-Madison
• 600 faculty, staff, students payrolled
• 250,000 sq ft building complex
• 5,000 patient visits in 2009
• ~ 90 grants from the NIH
• Multiple “centers within the WaismanCenter”
The Waisman Center’s Four Major Activities
Research Training
Service Outreach
Research throughout the life span
Waisman Center research on early learning, andhow poverty affects learning and development.
Waisman Center Stem Cell Research Laboratories
The neural stem cellprogram of the UW-Madison.
•We have discoveredhow stem cells can beturned into neurons.
•We are working todiscover how neuralstem cells can bespecialized to treatdiseases of the nervoussystem.
▲ Early stage retinal cells
Waisman Clinical Biomanufacturing Facility
Production ofpharmaceuticalsfor early stagehuman clinicaltrials.
Waisman Center Brain Imaging Facility
Expanding ourknowledge aboutbrain developmentand function usingMRI and PETscanning.
A New Center within the Waisman Center
•Directed by Dr.Richard Davidson
•The Dalai Lamaparticipated inopening celebration,scientific meeting atthe Waisman Center
The Center for Investigating Healthy Minds
•Research on attention, mindfulness, and other healthyqualities of the mind.
Training Future Researchers and Clinicians
Since it opened in 1973, the Waisman Centerhas trained more than 9,000 undergraduateand graduate students.
Waisman Early Childhood Program
•National leader in “inclusive”earlychildhood education.
•The WECP serves100 children birthto age five.
•1/3 of enrollmentare children withdisabilities.
Waisman Center Clinics
- Genetics
- Autism
- Fragile X Syndrome
- Feeding
- Cerebral Palsy
- Speech Disorders
- Computer-AssistedCommunication
- Neonatal Intensive CareFollow-up
Family Village: A World-wide Website Resource
More than 3 million people from throughout the worldhave visited this award-winning website.
Dane County Regional Airport Art Exhibit
•50 artworks, all bypeople withdevelopmentaldisabilities
•Sponsored by theFriends of the WaismanCenter.
•Curated by TandemPress.
•July 2010 throughJanuary 2011.
“Art is therapy for me.It creates a wholenew world.”
The Biggest House My GreatGrandfather Ever BuiltPhillip H. Porter © 2006
Acquired through theWisconsin Arts Board’sPercent for Art Program
July 10, 2010: Rotary “Dine Around”Lunch and Tour
Recent Visitors…
Visit the Waisman Center!
◘ 1500 Highland AvenueLocated on the west campus, across from UW Hospitaland ClinicsCall us! 263-5940