Watch video and PPT @:http://neurology.ufl.edu/divisions-2/neuroscience/gms-6096-introduction-to-nih-grant-writing-for-biomedical-sciences/

Please, complete evaluations. Important to assess faculty performance

pedro.fernandez@neurology.ufl.edu

Pre-submission review

Pedro Fernandez-Funez, PhD

Assistant Professor Department of Neurology

• Understand the complexity of the NIH grant proposal

• Identify all the components

• Work on a timeline to complete the proposal on time

By now, you should…

Documents to upload and submit: Minimum of 12

Scientific proposal:

✔Abstract

✔Narrative

✔Specific Aims

✔Research Strategy

✔References

Information:

✔Cover letter

✔PI Biosketch

✔Resource sharing

✔Facilities, Environment

✔Equipment

Review: Key documents

Budget:

✔Modular/detailed budget

✔Budget justification

Extra documents:

Key Personnel Biosketch

Support letter(s)

Consortium

Multiple PI

Proprietary info

Regulatory documents (depending on proposed research):

Human subjects

IRB permit

Vertebrate animals

IACUC permit

Documents to upload and submit: 15-20

Preview: Additional documents

Timeline for submission

Jun 5

Final Submission10-15 days

May 22

Complete Research Strategy for COM

1 month

May 5

Aims, Sign+Innovfor COM review

2 months

Apr 5Mar 19

Aims, Sign+Innovfor Dept. presentation

2.5 months

Mar 5

Title, Biosk, budgetCOI, humans? Animals?

3 months

Feb

Announce intent to submit

3-4 months

R01 deadlineReceived by NIH

-Upload to NIH form -Upload on PeopleSoft -Approvals: PI(s), Chair(s), Dean -COM-RAC review -DSR-UF review and submit

Budget justific, Animals, humans, facilities

1.5 months

• You don’t have to submit a detailed budget to the NIH, if below 250K/year

• BUT, you HAVE to your college !

The Budget trap !

• Project Summary/Abstract- 30 lines or less

• You will need to send an introduction to

application only if this is a resubmission.

• Specific Aims- 1 page !!!

• Research Strategy – Page limits by mechanism

or guidelines (12 p. R01, 6 p. R21, R03)

• Significance and Innovation: 1 page, part of

Research Strategy

• References Cited-Full citations, no page limits

Completing the science

Summary / Abstract

• Could be considered the most important part of your application since every reviewer in the panel will likely read it

• 30 lines or less !

• Do not include proprietary information

• If awarded, it will appear on RePORTER

Summary / Abstract

• Stand alone document: most reviewers will not read the specific aims or the proposal

• Should be written last to make sure it clearly reflects the content of your proposal

• Open by describing gap in knowledge followed by key sentences in the Specific Aims

• Copy the Specific Aims and primary methods

• Finish with statements of Significance and Innovation

Project Narrative• No more than 2 or 3 sentences

• Layman language

• Meant to describe the relevance to public health and how it relates to the NIH mission

Public Health Relevance/Narrative: Carolina Wahlby, 2010Large-scale screening experiments that test the effects of thousands of chemicals or genetic perturbants by microscopy and image analysis can discover new treatments and help biomedical scientists understand disease mechanisms. Microscopy screens of cultured cells are routine, but researchers wish to study complex processes like metabolism and infection in a whole animal like the tiny worm Caenorhabditis elegans, for which existing image analysis methods are insufficient. The goal of this research is to develop open-source software to automatically identify and measure C. elegans in microscopy images, thereby making it possible for researchers worldwide to screen a wide variety of complex biological processes related to human disease.

Cayuse 424

http://research.ufl.edu/research/proposal/cayuse/cayuse-proposal.html#search

New software that allows PI to prepare grant application on their own

Cayuse 424

Cayuse 424

MyinvestiGator

My Investigator

• Be responsive to requests from your grants people. After all, it is YOUR grant

• Your grants person does not submit directly to NIH. Many internal steps to get it through the system

Remember !

Congratulations !

You completed the course !