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CURRICULUM(Scheme & Syllabi for 3rd Year)

For

UNDERGRADUATE DEGREE COURSE

IN

BIOMEDICALENGINEERINGScheme C

(w.e.f. 2020-21)

DEENBANDHU CHHOTU RAM UNIVERSITY OF SCIENCE AND TECHONOLOGY(Established Under Haryana Legislature Act NO. 29 of 2006)

Murthal-131039, Sonipat (Haryana)www.dcrust.ac.in

B. Tech. 3rd Year (V & VI semester) Bio-Medical Engg.: Approved in 15 th meeting of Academic Council held on 14.08.2020. applicable to all students admitted in 2018-19 & onwards and trailing students.

Deenbandhu Chhotu Ram University of Science & Technology, Murthal (Sonepat)SCHEME OF STUDIES & EXAMINATIONS

B. Tech. Biomedical Engineering 3rdYEAR (SEMESTER –V) Choice Based Credit Scheme w.e.f. 2020-2021

S. No. Course

Code Course Title

Teaching Schedule

Marks of

Class work

Examination Marks Tota

lCredi

tDuration of ExamL T P Theory Practic

al

1 BME301C Biomechanics & Rehabilitation Engineering 3 0 0 25 75 0 100 3 3

2 BME381C Biomechanics & Rehabilitation Engineering Lab 0 0 2 25 0 75 100 1 3

3 BME303C Biomedical Equipments -II 3 0 0 25 75 0 100 3 3

4 BME383C Biomedical Equipments –II Lab 0 0 2 25 0 75 100 1 3

5 BME305C Digital System Design 3 0 0 25 75 0 100 3 3

6 BME385C Digital System Design Lab 0 0 2 25 0 75 100 1 3

7 BME307C Control Systems 3 0 0 25 75 0 100 3 3

8 BME309C Biosensors & Biotransducers 3 0 0 25 75 0 100 3 3

9 Professional Elective Course -I 3 0 0 25 75 0 100 3 3

10 BME391C Professional training (Level-2) 0 0 2 100 0 0 100 2 0

11 MC301C Essence of Indian Traditional Knowledge 3 0 0 25 75 0 100 0 3

Total 21 0 8 350 525 225 1100 23

Professional Elective Courses-IBME321CClinical EngineeringBME323CMedical PhysicsBME325CBiomedical Ethics & Device RegulationBME327CBiostatistics

Notes:

1. For student admitted in B. Tech. 1st Semester (C-Scheme) in 2019 and all trailing students, Examinations and evaluation of students shall be conducted as per guidelines AICTE Examinations Reforms covering the entire syllabus. The students shall be made aware about the reforms.

2. The use of programmable devices such as programmable calculators, phones etc. and sharing of any material during examination are not allowed.

3. A specific note shall be inserted in relevant question paper wherever the use of graph papers, semilog papers, steam tables, etc. shall be allowed during examination.

4. Assessment of Professional training (Level-2) (BME391C) carried out during summer vacation will be based on seminar, viva-voce, report and certificate of professional training obtained by the student from Supervisor.


Deenbandhu Chhotu Ram University of Science & Technology, Murthal (Sonepat)SCHEME OF STUDIES & EXAMINATIONS

B. Tech. Biomedical Engineering 3rdYEAR (SEMESTER –VI) Choice Based Credit Scheme w.e.f. 2020-2021

S. No. Course

Code Course Title

Teaching Schedule

Marks of

Class work

Examination Marks Tot

al CreditDuration of ExamL T P Theory Practic

al1 BME302C Medical Biomaterials 3 0 0 25 75 0 100 3 3

2 BME382C Medical Biomaterials Lab 0 0 2 25 0 75 100 1 3

3 BME304C Medical Imaging 3 0 0 25 75 0 100 3 3

4 BME384C Medical Imaging Lab 0 0 2 25 0 75 100 1 3

5 BME306C Microcontrollers 3 0 0 25 75 0 100 3 3

6 BME386C Microcontrollers Lab 0 0 2 25 0 75 100 1 3

7 BME308C Biological Control Systems 3 0 0 25 75 0 100 3 3

8 Professional Elective Course -II 3 0 0 25 75 0 100 3 3

9 OL-I Open Elective-I 3 0 0 25 75 0 100 3 3

Total 18 0 6 225 450 225 900 21

Professional Elective Courses-IIBME322C Modelling & SimulationBME324C Biomedical Image ProcessingBME326C Hospital ManagementBME328C Principles of Bioengineering

Open Elective-IHUM201CSoft Skills and Interpersonal CommunicationHUM Professional Communication for Engineers(Except BT & BME)MGT Human Resource ManagementMGT Human Values Ethics and IPRHUM Introduction to Language German HUM Introduction to Language French

Notes:

1. For student admitted in B. Tech. 1st Semester (C-Scheme) in 2019 and all trailing students, Examinations and evaluation of students shall be conducted as per guidelines AICTE Examinations Reforms covering the entire syllabus. The students shall be made aware about the reforms.

2. The use of programmable devices such as programmable calculators, phones etc. and sharing of any material during examination are not allowed.

3. A specific note shall be inserted in relevant question paper wherever the use of graph papers, semilog papers, steam tables, etc. shall be allowed during examination.

4. At the end of VI semester, each student has to undergo Professional Training (level-3) of atleast four weeks from industry/institute/research lab/training


center during summer vacation and its evaluations shall be carried out in the VII semester.

BME301C: Biomechanics & Rehabilitation EngineeringB. Tech. 3rd Year (Semester –V)

L T P Credits Class Work : 25 Marks

3 - -- 3 Examination : 75 Marks

Total : 100 MarksDuration of Examination : 3 Hours

Unit IGeneral Principles: Introduction to biomechanics, kinesiology, basic mechanical concepts, types of motion, movement terms. Basic kinematics concepts, vectors & trigonometry, Position of anatomical axis & corresponding movements of the body part, free body diagram.

Unit IITissue Biomechanics: Solids and Structures: Biological Materials Properties, Viscoelasticity, Simple Structure, Hydrostatic Structure, Structural Systems, Biomechanical characteristic of bone & the soft tissue: tendons, ligaments, muscles, function & physiological factors, frequency of firing motor units, muscle recruitment

Unit IIIPatterns: Push/Throw Continuum: Biomechanics of push - like motions, Biomechanics of throw - like motionsMovement Biomechanics: Gait analysis, body & limbs: mass & motion characteristics, forces transmitted by joints. Joints forces resulting in normal & disable human body, normal & fast gait.

Unit IVProsthetics & Orthotics: Principles in designing orthosis & prosthesis: Principles of three-point pressure, total constant and partial weight relieving, Design Considerations, Purpose for providing prostheses &orthosis: Various aspects regarding diagnosis, prognosis, stature & socio-economic condition, Classification in prosthetics &orthosis: Lower Extremity orthosis& prostheses, Upper Extremity orthosis& prosthesis, Spinal orthosis, Recent developments in prosthetics &orthosis.TEXT BOOKS1. Kinesiology: The Mechanics and Pathomechanics of Human Movement- Carol A. Oatis, Lippincott Williams and Wilkins2. Introductory Biomechanics -C. Ross Ethier, Craig A. Simmons, Cambridge University PressREFERENCE BOOKS1. Human limbs and their substitutes-Paul E. Klopsteg, Mcgraw Hill2. Biomechanics in the Musculoskeletal System , Manohar M. Panjabi and Augustus A. White III, Churchill Livingstone3. Text book of Rehabilitation- S.Sunder, JayPee Brothers, Medical Publishers Pvt. Ltd. 20084. Biomedical Engineering Fundamentals - Joseph D. Bronzino, Donald R. Peterson, CRC press.COURSE OUTCOMES After the completion of the course the students will be able to1. Draw and understand free body diagram.2. Understand the characteristics of bone and soft tissues.3. Analyze different Gait patterns.4. Design the simple prosthetics and orthotics used in biomechanics.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering

the entire syllabus. The students will be required to attempt only five questions selecting atleast one question from each unit.

2. The use of scientific calculator will be allowed in the examination. However, programmable calculator and cellular phone will not be allowed.


For students admitted in B. Tech. 1st Year (C-Scheme) in 2019 and all trailing students. Examinations and evaluation of students shall be conducted as per guidelines of AICTE Examinations Reforms covering the entire syllabus. The students shall be made aware about the reforms.

BME381C: Biomechanics & Rehabilitation Engineering LabB. Tech. 3rd Year (Semester –V)


- - 2 1 Examination : 75 Marks


EXPERIMENTS1. To determine the coefficient of static friction between two given material surfaces with the help of an inclined plane.2. To demonstrate and analyze the lever action by using Bell Crank Lever of the human muscle.3. Stress strain analysis of lower limb prosthesis using 16channel BIOPAC system.4. To determine the hardness of given bone using hardness tester.5. To determine the moment of Inertia of a stepped pulley or a flywheel.6. To determine the effect of the principle of conservation of angular momentum on human body.7. To determine the mechanical properties of bone using UTM.8. To verify Bernoulli s Theorem, for fluid flow through pipes.9. To demonstrate gate analysis and center of gravity on a plane figure.10. To determine muscle force using dynamometer. OUTCOMESAfter performing the experiments the students will be able to1. Visualize the principles of mechanics, physiology and fluid mechanics on to human body.2. Understand the working and movement of human body in a better manner along with corrective measures.3. Experience exposure to various modalities available for biomechanical studies and the latest advancements.4. Analyze the importance of multidisciplinary studies in the lab work.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.



BME303C: Biomedical Equipments –IIB. Tech. 3rd Year (Semester –V)




Unit ICardiac Pacemakers: Need for a pacemaker, External and Implantable pacemaker, Asynchronous and Synchronous (demand) modes of operation, programmable pacemaker, power sources for implantable pacemakers, Lead wires and electrodes with their problems.

Unit IIProsthetic heart valves and Heart lung machine: Qualitative requirements categories; Mechanical and tissue valves, types of medical valves: ball and cage, tilting disc, and bileaflet valves; types of tissue valves. Governing principles and usage of heart lung machine, functional details of blood oxygenators

Unit IIIAssist devices for the healthcare: Principles of external counter pulsation techniques, intra-aortic balloon pump, Essentials of Hearing Aids-block diagram, Defibrillator machine, Nerve and Muscle stimulators, Lithotriptor, Extra Corporeal Shock Wave Therapy.

Unit IVAnesthesia and Ventilator machine: Need for Anesthesia and machine, Electronics in anesthesia machine, Mechanism of Respiration, Artificial Ventilation, Ventilators and types, pressure volume-flow diagrams. TEXT BOOKS1. Biomedical Engineering and Instrumentation- Joseph Bronzino, PWS Engineering2. Introduction to Biomedical Equipment Technology- J.J.Carr & J.M.Brown, Pearson Education3. Biomedical Instrumentation & Measurement- Cromwell, Weibell & Pfeiffer, Prentice HallREFERENCE BOOKS1. Handbook of Bio-Medical Instrumentation- R. S. Khandpur, McGraw Hill Education2. Medical Instrumentation, Application and Design-John G. Webster, John Wiley & SonsCOURSE OUTCOMES After the completion of the course the students will be able to1. Describe and characterize different types of pacemakers, their needs and limitations.2. Understand, describe and characterize various Heart Valves & components of H-L Machine.3. Understand and describe assistive devices and their necessity in healthcare system.4. Familiarize with different controls of Anesthesia and Ventilator machine. Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering





BME383C: Biomedical Equipments –II LabB. Tech. 3rd Year (Semester –V)




EXPERIMENTS1. To design and realize synchronous/ asynchronous pacemaker.2. To realize the controls of Defibrillator machine.3. Analyze different types of oxygenators used in hemodialysis machine.4. To demonstrate the working of anesthesia and ventilator machine with different controls.5. To realize the working and design of neuromuscular stimulator.6. To simulate different modes of triggering in artificial pacemaker.7. To realize and investigate the results of Advance Biofeedback system.8. To investigate stress test analysis using TMT machine.9. To analyze Nerve and muscle conduction using PC based Physiology system.10. To realize the working of ENG machine.OUTCOMESAfter performing the experiments the students will be able to1. Describe the designs of synchronous and asynchronous pacemakers.2. Describe and characterize various oxygenators used in hemodialysis machine.3. Describe the working of PC based physiology system and neuromuscular stimulators.4. Familiarize with the different controls of Defibrillator, TMT, ENG, Anesthesia and Ventilator machine.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.



BME305C: Digital System DesignB. Tech. 3rd Year (Semester –V)




Unit IFundamentals Of Digital Techniques: Digital signal, logic gates: AND, OR, NOT, NAND, NOR, EX-OR, EX-NOR, Boolean algebra. Review of Number systems. Binary codes: BCD, Excess-3, Gray, EBCDIC, ASCII, Error detection and correction codesCombinational Design Using Gates: Design using gates, Simplifications of SOP and POS Boolean Expressions, Karnaugh map up to four variables.

Unit IICombinational Design Using MSI Devices: Multiplexers and Demultiplexers, Decoders, Adders/ Subtractor, BCD arithmetic circuits, Encoders, Code Converters, Decoders/Drivers for display devices.Sequential Circuits: Flip Flops: S-R, J-K, T, D, master-slave; shift registers, sequence generators; Counters: Ring counters and Johnson Counter, Design of Synchronous and Asynchronous sequential circuits.

Unit IIIDigital Logic Families: Bipolar logic families: RTL, DTL, DCTL, HTL, TTL, ECL, MOS, and CMOS logic families. Tristate logic, Interfacing of CMOS and TTL familiesSemiconductors Memory Devices: Memory organizations, Characteristics of memory devices, Classifications of semiconductors memories.

Unit IVA/D and D/A Converters: Sample and hold circuit, weighted resistor and R -2 R ladder D/A Converters, specifications for D/A converters. A/D converters: Quantization, parallel -comparator, successive approximation, counting type, dual-slope ADC, specifications of ADCs.Programmable Logic Devices:PLA, PAL, FPGA and CPLDs. TEXT BOOKS1. Modern Digital Electronics - R. P. Jain, McGraw-Hill 2. Digital Electronics- Green, Pearson EducationREFERENCE BOOKS1. Digital Integrated Electronics- Taub & Schilling, McGraw-Hill 2. Digital Principles and Applications – Malvino & Leach, McGraw-Hill3. Digital Design- Morris Mano, Prentice HallCOURSE OUTCOMES


After the completion of the course the students will be able to1. Develop a digital logic and apply it to solve real life problems.2. Analyze, design and implement combinational and sequential logic circuits. 3. Classify different semiconductor memories. 4. Develop digital system design using PLD.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME385C: Digital System Design LabB. Tech. 3rd Year (Semester – V)




EXPERIMENTS1 To verify logics of TTL gates AND,OR,NOT,NAND,NOR,EX-OR,EX-NOR2 Design & realize a given function using K-maps and verify its performance.3 To verify the operation of Multiplexer & De-multiplexer.4 To verify the operation of Comparators.5 To verify the truth table of S-R, J-K, and T & D Type flip flop.6 To verify the operation of bi-directional shift register.7 To design & verify the operation of 3 bit synchronous counter.8 To design & verify the operation of synchronous/asynchronous UP/DOWN decade counter using JK FF9 To design and realize a sequence generator for a given sequence using JK flip- flop.10 Study of CMOS, NAND & NOR gates and interfacing between TTL and CMOS gates.11 Design a 4- bit shift register and verify its operation.12 To verify the operation of a ring counter and a Johnson counterOUTCOMES On successful completion of the experiments, the student will be able to 1 Distinguish between analog and digital systems. 2 Apply Boolean laws to simplify the digital circuits. 3 Design simple logic circuits.4 Design simple sequential circuits.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.



BME307C: Control SystemsB. Tech. 3rd Year (Semester – V)




Unit IInput / Output Relationship: Open loop & closed loop control system & their illustrative examples, Mathematical modeling and representation of physical systems, Concept of transfer function, relationship between transfer function and impulse response, order of a system, block diagram algebra, signal flow graphs: Mason s gain formula & its application, characteristic equation

Unit IITime Domain Analysis: Typical test signals, time response of first order systems to various standard inputs, time response of 2nd order system to step input, time domain specifications, steady state error and error constants, concept of stability, pole-zero configuration and stability, necessary and sufficient conditions for stability, Routh stability criterion and relative stability. Root locus concept

Unit IIIFrequency Domain Analysis: Relationship between frequency response and time-response for 2nd order system, Polar& Nyquist plots, Bode plots: stability, Gain-margin and Phase Margin, relative stability

Unit IVCompensation: Necessity of compensation, compensation networks, application of lag and lead compensation, basic modes of feedback control, proportional, integral and derivative controllers.Control Components: Synchros, servomotors &stepper motorsTEXT BOOKS1. Control System Engineering-I.J. Nagrath & M. Gopal, New Age International (P) LimitedREFERENCE BOOKS1. Automatic Control Systems- B.C. Kuo, John Wiley & Sons2. Modern Control Engineering- K. Ogata,Pearson3. Control Systems - Principles & Design- Madan Gopal, Tata McGraw-Hill4. Modern Control Engineering- R.C. Dorf & Bishop, PearsonCOURSE OUTCOMES After the completion of the course the students will be able to1. Develop a mathematical model of control systems.


2. Predict and analyze the stability of different systems. 3. Draw frequency plot of systems.4. Design the controller required for a particular control systemNote:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME309C: Biosensors & BiotransducersB. Tech. 3rd Year (Semester – V)




Unit ITransducers principles and Medical applications:Classification of transducers, characteristic of transducers, Temperature transducers: Resistance temperature detector (RTD), Thermistor, Thermocouple, p-n junction, chemical thermometry, Displacement transducers: potentiometer, resistive strain gauges, inductive displacement, capacitive displacement transducer, Pressure transducer: variable capacitance pressure transducers, LVDT transducers, strain gauge transducers, semiconductor transducers, catheter tip transducers, Piezoelectric transducer, Photoelectric transducers: photo-emissive tubes, photovoltaic cell, photoconductive cell, photodiodes, Flow transducers: magnetic, resistive and ultrasonic

Unit IIBiochemical Transducers: Electrode theory: electrode-tissue interface, metal-electrolyte interface, electrode-skin interface, electrode impedance, Biopotential electrodes: microelectrodes, body surface electrodes, needle electrodes, electrodes for ECG, EEG, and EMG. Reference electrodes: hydrogen electrodes, silver-silver chloride electrodes, Calomel electrodes, Ion electrodes: specific ion electrodes, pH electrode, O2 electrode, CO2 electrode.

Unit IIIIntroduction to biosensors and classification. Different transduction mechanisms in sensors. Types of recognition layers. Examples and functioning of different types of biosensors including, but not restricted to, optical, mechanical (e.g. microcantilever, piezo, SAW, etc), electrochemical, FET, thermal, etc. Analytical modelling of biosensors.

Unit IVBiological sensors: Sensors / receptors in the human body, basic organization of nervous system-neural mechanism, Chemoreceptor: hot and cold receptors, barro receptors, sensors for smell, sound, vision, Ion exchange membrane electrodes, enzyme electrode, glucose sensors, immunosensors, Basic principles of MOSFET biosensors & BIOMEMS, basic idea about Smart sensors.TEXT BOOKS1. The Biomedical Engineering Handbook-Joseph D. Bronzino, CRC press.


2. HandbookofBiomedicalInstrumentation-R.S.Khandpur, McGraw Hill EducationREFERENCE BOOKS1 PrinciplesofMedicalElectronics&BiomedicalInstrumentation-Rao&Guha,Universities Press2.Touch Heat & Pain-A.V.S. De Renck, Churchill Ltd. London3. Applied Bio Sensors-D. L. Wise, Butterworth-HeinemannCOURSE OUTCOMES After the completion of the course the students will be able to1. Gain adequate knowledge about transduction and transducers.2. Get clear idea about biochemical transducers.3. Have in-depth knowledge about different types of biological sensors.4. Explain and design different types of Biosensor.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering the

entire syllabus. The students will be required to attempt only five questions selecting atleast one question from each unit.



Professional Elective Courses – I

BME321C: Clinical Engineering

B. Tech. 3rd Year (Semester – V)L T P Credits Class Work : 25 Marks



Unit INephrology: Diseases of Kidney, Principles of dialysis: Types of dialyzers, controls and monitoring devices for dialyzers, Hemodialysis and peritoneal dialysis, portable kidney machines, Clearance, dialysance, Components of dialyzing system, Dialysate, composition of dialysate, Clinical significance. Renal transplantation: Basic principles.

Unit IINeurology: Diseases of nervous system, Electroencephalography, neuromuscular stimulation, Electromyography, Clinical applications. Motor neuron disorders, the electrical study of reflexes, the silent period. The F response, The H reflex, the axion reflexes, Disorders of neuromuscular transmission.

Unit IIIGeneral Surgery & Gastroenterology: Pre- operative preparation for surgical patient, Study and operation of surgical equipment, safety aspects in electro-surgical units, Anatomy and physiology of G.I.T. Nutritional support and parenteral therapy, Height and weight estimations according to age. Intravenous cannulae, stomach wash tubes, Introduction to Hypertension and Diabetes.

Unit IVOpthalmology: The genesis and basis of electroretinogram (ERG) diagnosis& electrooculogram (EOG) with applications, Color Vision testing equipment, Sneller s chart, keratometer, refractometer, Slit lamp biomicroscopy, opthalmoscope, retinoscope, tonometer, perimeter, contact lenses.TEXT BOOKS1. Approach to Clinical Neurology- James G. Mcleod, Physiological, Butterworth-Heinemann


2. Introduction to Biomedical Equipment Technology -J.J.Carr & J.M.Brown, Pearson Education3. System of Ophthalmology Vol VII- Duke Elder, The C.V. Mosby CompanyREFERENCE BOOKS1 Diseases of kidney- Strauss, Maurice B. & Louis G.Welt, Little Brown, Boston2. Handbook of Bio-Medical Instrumentation- R. S. Khandpur, McGraw Hill EducationCOURSE OUTCOMES After the completion of the course the students will be able to1. Apply theoretical concepts to interpret physiological signals.2. Recognize clinical conditions associated with nervous and muscular system3. Demonstrate knowledge about clinical conditions such as hypertension and diabetes4. Measure biomedical and physiological information available in ERG/EOGNote:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME323C: Medical PhysicsB. Tech. 3rd Year (Semester – V)




Unit IHeat and Cold in Medicine: Thermography and temperature scales, mapping of body's temperatures. Heat therapy, use of cold in medicine, Cryosurgery and safety aspects. Energy, Work, Power and Pressure: Conservation of energy in the body. Energy changes in the body. Work, power heat losses of body. Measurement of pressure in the body, pressure inside Skull, Eye, Digestive system, Skeleton, Urinary bladder etc. Hyperbaric oxygen therapy.

Unit IIPhysics of the Lung & Breathing: The airways, blood & lung interaction, measurement of lung volumes Pressure flow-volume relationship of the lungs. Physics of the alveoli. Breathing mechanism, airway resistance. Work of breathing. Physics of some common lung diseases. Physics of the Cardiovascular system: Major components of the Cardiovascular system. Oxygen and Carbon dioxide exchange in the capillary system. Bemou1li's principle applied to Cardiovascular system. Laminar and turbulent blood flow. Heart sounds. The physics of some cardiovascular diseases.

Unit IIIElectricity within the body: The nervous system and neurons. Electrical potentials of nerves, Electroretinogram and Electrooculogram, Electrical impedance tomography, Magneto cardiogram and Magneto encephalogram. Electric shock. High frequency & low frequency electricity in medicine and magnetism in medicine, Functional MRI.

Unit IVSound in Medicine: General properties of sound, body as a drum, stethoscope, Ultrasound


picture of the body, Ultrasound to measure motion, production of speech, Artificial speech processing.Light in Medicine: Measurement of light & its units, Applications of Visible light in medicine, Applications of UV & IR in medicine, LASERS in medicine.TEXT BOOKS1 Medical Physics -J R Cameron & J G Skofronick, Wiley & SonsREFERENCE BOOKS1 Intermediate Physics for Medicine and Biology - Russell K. Hobbie & Bradley J. Roth, Springer-Verlag New YorkCOURSE OUTCOMES After the completion of the course the students will be able to1 Analyze the mapping of body's temperatures.2 Measure the lung volumes and relate it to lung diseases.3 Distinguish between the high and low frequency electricity effects in medicine.4 Apply the concept of light in designing medical devices.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME325C: Biomedical Ethics & Device RegulationB. Tech. 3rd Year (Semester – V)




Unit ISources of Medical Law and Ethics: Nature and sources of medical ethics, Sources of medical law. Consent, Confidentiality and Clinical Negligence: Consent to Treatment, Confidentiality and Clinical Negligence.

Unit IIMental Health: Types of mental health, Adults with Incapacity.Issues:The law&ethicsin relation to abortion, Reproductive Technology and Surrogacy, The law in relation to end of life issues, The ethics of end of life issues and Research.

Unit IIIMaintaining professional standards: Maintaining standards and regulation, Presenting evidence and reports, The Coroner's court, The General Medical Council, Doctors rights: Employment and other rights of doctors

Unit IVDevice regulation: Classifications and requirements of Medical devices, Harmonized standards ,CE approval , Quality Assurance and Quality Definition of quality, quality management, principles of TQM, measures for Quality Control. Safety & Testing of Medical devices -patenting. TEXT BOOKS1.Intervention and Reflection: Basic Issues in Medical Ethics -Ronald Munson, Cram101


2. Ethics of Health Care: An Introductory Textbook–B. M. Ashley, K. D. O'Rourke, Georgetown University PressREFERENCE BOOKS1 Introduction to Bio-Medical Engineering-John D. Enderle, Susan M. Blanchard, Academic PressCOURSE OUTCOMES After the completion of the course the students will be able to1. Understand basics about nature and sources of medical ethics.2.Apprehend the importance of quality control for medical devices.3.Gain knowledge about the regulation of medical devices.4. Realize the importance of maintain professional standardsNote:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME327C: BiostatisticsB. Tech. 3rd Year (Semester – V)




Unit IIntroduction to probability: random experiments, concept of probability, axioms and theorem of probability, conditional probability, Bayes theorem, fundamental principle of counting, continuous & discrete distributions, special probability distributions.

Unit IISampling and estimation theory: Scope & Purpose of statistics, population and sample, computation of mean, variance and moments for grouped data. Estimation theory: point estimates and interval estimates, confidence interval estimates, maximum likelihood estimates.Tests of hypotheses and significance: statistical hypothesis, null hypothesis, type I and type II errors, level of significance, one tailed and two tailed tests, P value, special test of significance for large and small samples, Chi-square test for goodness of fit & students t-test.

Unit IIICurve fitting, regression and correlation: regression, method of least squares, multiple regression, generalized correlation coefficient, probability interpretation of regression and correlation.


Analysis of variance: purpose of analysis of variance, one-way classifications & two way classifications.

Unit IVExperimental design: Clinical trials-study design, organization and planning, randomized clinical trials, factorial, Latin square, and sequential cross-over design, F Test and Applications. TEXT BOOKS1 Fundamentals of Biostatistics - Bernard Rosner, Cengage LearningREFERENCE BOOKS1 Modern Medical Statistics: A Practical Guide- Brian S. Everitt, Oxford University Press2 Statistics : A Biomedical Introduction -Byron Wm. Brown, Myles Hollander, John Wiley & Sons3 Statistical Methods for the Analysis of Biomedical Data- Robert F. Woolson, William R. Clarke,John Wiley & Sons4 An Introduction to Medical Statistics-Martin Bland,Oxford University PressCOURSE OUTCOMES After the completion of the course the students will be able to1 Select from, use and interpret results of, descriptive statistical methods effectively.2 Demonstrate an understanding of the modern statistical theory and its probabilistic foundation.3 Communicate the results of statistical analyses accurately and effectively.4 Read and learn new statistical procedures independently lifelong.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME302C: Medical BiomaterialsB. Tech. 3rd Year (Semester – VI)




Unit-IIntroduction: Definition of biomaterials, requirements of biomaterials, classification of biomaterials, Comparison of properties of some common biomaterials. Surface properties, physical properties and mechanical properties of materials. Host tissue reactions to biomaterialsMetallic implant materials: Stainless steel, Co-based alloys, Ti and Ti-based alloys. Importance of stress-corrosion cracking, corrosion behavior and the importance of passive films for tissue adhesion. Hard tissue replacement implant: Orthopedic implants and Dental implants. Soft tissue replacement implants: Percutaneous,skin implants and vascular implants

Unit IIPolymeric implant materials: Polymerization, factors influencing the properties of polymers, polymers as biomaterials, biodegradable polymers, Bio polymers: Collagen, Elastin and chitin. Biodegradable polymers for medical purposes, Biopolymers in controlled release systems, Synthetic polymeric membranes and their biological applications.


Ceramic implant materials: Definition of bioceramics. Common types of bioceramics: Aluminium oxides, Glass ceramics, Carbons. Bioresorbable and bioactive ceramics

Unit IIIMaterial Characterization: Analytical Instruments for material characterization like DSC, SEM, Contact Angle measurements, TGA.Biocompatibility & toxicological screening of biomaterials: Definition of biocompatibility, blood compatibility and tissue compatibility.

Unit IVSterilization Techniques: Definition of sterilization, Types of sterilization: autoclaving, ETO and gamma radiation. Effect of sterilization on the properties of materials.Testing of biomaterials/Implants: Toxicity tests: acute and chronic toxicity studies (in situ implantation, tissue culture, haemolysis, thrombogenic potential tests, systemic toxicity, intracutaneous irritation test), sensitization, carcinogenicity, mutagenicity and special tests. In vitro and In vivo testing. Standard of implant materials.TEXT BOOKS1. Biomaterials- SujataV. Bhatt, Alpha Science International2. Biomaterials: A Nano Approach- Sreeram Ramakrishna et. al., CRC PressREFERENCE BOOKS1. Biomaterials science: An introduction to materials in medicine-Ratner B, Hoffman A. et al., Academic Press.2. Biomaterials, Medical Devices & Tissue Engineering: An integrated approach-Fredrick H. Silver, Chapman and Hall3.Biomaterials Science and Engineering-Park J.B., Springer USCOURSE OUTCOMES After the completion of the course the students will be able to1. Identify different types of Medical Biomaterials and apply the concept of nanotechnology towards medical use.2. Identify significant gap required to overcome challenges in fabrication of metallic and ceramic materials3. Create combinations of materials that could be used as a better tissue replacement implant.4. Understand the testing standards applied for biomaterials.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




B. Tech. 3rd Year (Semester – VI)L T P Credits Class Work : 25 Marks



EXPERIMENTS1. Survey the commonly used equipments in biomaterial laboratory and enlist them.2. The preparation of calcium sulphate beads.3. Preparation of hydrogel patch of HEMA.4. Characterization studies of HEMA patch by FTIR5. Preparation of drug loaded HEMA patch.6. Evaluation of the drug loading efficiency.7. Preparation and characterization of bone cement.8. To study Biomechanical properties of given sample using INSTRON machine.9. Elaborate the basic components of Hip implant.9. Preparation of polyvinyl alcohol film.10. Estimation and assay of biological enzymes.


OUTCOMESAfter performing the experiments the students will be able to1. Visualize the hip implant and its types.2. Understand the working and results of FTIR and similar characterization instruments.3. Experience preparation of HEMA patch.4. Analyze the importance of bioimplants.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.


BME304C: Medical ImagingB. Tech. 3rd Year (Semester – VI)




Unit IIntroduction: Introduction to medical imaging technology, systems, and modalities. Image properties: contrast and spatial resolution.X-ray imaging: Electromagnetic spectrum, structure of atom, interaction of radiation with matter, Properties of X-rays, attenuation of X-rays in tissue, quantification of X-rays, patient specific radiation risk estimation, X - Ray tubes and generators, Instrumentation of planar X-rays

Unit IIRadiology: Angiography, fluoroscopy, and mammography. Digital radiography, C-ARM & Dental X-Ray.Computed tomography: Principles of computed tomography, Hardware of C T. Spiral/helical


computed tomography. Clinical applications of CTUnit III

Thermography & Optical imaging: Physics of Thermography, Infrared Detectors, Thermography equipment and IR sensor, advantages of optical imaging, optical coherence tomography.Ultrasound: Principles of Ultrasound imaging, Wave propagation and characteristic acoustic impedance, Interaction with tissue, Ultrasound Instrumentation, Diagnostic scanning modes, artifacts in ultrasonic imaging, ultrasonic image characteristics, Color Doppler, Clinical applications of ultrasound.

Unit IVMagnetic Resonance Imaging: physics of NMR, magnet (superconducting magnets, permanent magnets), magnetic field gradients, the NMR coil/probe, data acquisition. Clinical applications of MRI.Emission Tomography: Radioactivity, type of detectors and basic principles, Anger scintillation camera. Nuclear Imaging: SPECT/PET instrumentation and clinical applicationsTEXT BOOKS1. Introduction to Biomedical Imaging-Andrew G. Webb, Wiley-IEEE Press2. Fundamentals of Medical Imaging -Paul Suetens, Cambridge UniversityREFERENCE BOOKS1.The essential physics of medical imaging-. J. T. Bushberg, J.A. Seibert, E.M. Leidholdt Jr., J. Boone,LWW2. Essentials of Ultrasound. – Michael R. Williamson, SaundersCOURSE OUTCOMES After the completion of the course the students will be able to1. Select proper imaging modality depending upon clinical condition of the subject.2. Apprehend the importance of radiation constructive utilization and safety.3. Identify the artifacts present during ultrasonic imaging.4. Develop basic concepts of MRI and Emission tomography.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME384C: Medical Imaging LabB. Tech. 3rd Year (Semester – VI)




EXPERIMENTS1. To demonstrate the physics & principles underlying the operation of medical imaging equipment.2. To realize the basics of X-ray imaging modality with different operating controls.3. To demonstrate the Imaging of soft tissues using CT and MRI. 4. To verify the Principles of Infra-Red Imaging. 5. To demonstrate the working Principle of Angiography and Fluoroscopy.


6. To demonstrate the working Principle of PET and SPECT. 7. To identify and analyze the basics of Ultra Sound imaging modality. 8. To interpret the most effective imaging modality for a particular organ.9. To analyze the Radiation safety issues in the operation of medical imaging equipments.10. To characterize the clinical applications and limitations of different imaging methods.OUTCOMESAfter performing the experiments the students will be able to1. Understand and describe the basics of X-ray imaging modality and its biological effects. 2. Understand and describe the fundamentals of CT imaging 3. Understand and explain the principles of Fluoroscopy and angiography. 4. Understand and explain the principles of Infra red imaging.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.


BME306C: MicrocontrollersB. Tech. 3rd Year (Semester – VI)




Unit IArchitecture of Typical Microcontrollers: Overview of programming model, instruction set, interface to external memory; use of stack in subroutine calls and interrupt services; access of built-in I/O ports, timers and counters.

Unit IISoftware Development Environment: Features of a selected macro assembler, working


principle of assembler; assembler directives, examples of assembly language programs; features of a selected C compiler, examples of C programs for controlling microcontrollers.

Unit IIII/O Interfacing: Output-pin driving limitations, current driving, inductive load driving; pulse generation and measurement; keyboard scanning, display multiplexing, LCD controllers, use of peripheral interface IC; analogue signal sensing, analogue and digital conversion; serial interface standards; examples of microcontroller- based industrial I/O standards..

Unit IVEmbedded Software Development and Testing: Embedded software issues; tasks and events; interrupt system: nesting, priority and latencies; simulator, debugger and emulator.TEXT BOOKS1. The 8051 Microcontroller And Embedded Systems -Muhammad Ali Mazidi, Pearson Education2. 8051 Microcontroller: An Applications Based Introduction-F. Cowan, Hassan Parchizadeh, Newnes3. The 8051 Microcontroller & Embedded Systems using Assembly and C-K. J. Ayala, D. V. Gadre, Cengage New DelhiREFERENCE BOOKS1. Microcontrollers Architecture, programming, interfacing and system design-Raj Kamal, Pearson Education2. Microcontrollers and Applications-Ramani Kalpathi and Ganesh Raja, Sanguine Technical 3. Microcontrollers: Theory and Applications-A.V. Deshmukh, McGraw-Hill4. Microprocessors and Interfacing: Programming and Hardware-D.V. Hall, McGraw-HillCOURSE OUTCOMES After the completion of the course the students will be able to1. Understand the fundamentals of microcontroller systems and interface, and have the ability to apply them. 2. Conduct experiments, as well as to evaluate the outcomes.3. Identify, formulate and solve problems by using the concepts of microcontroller systems and interface4. Use simulation tools to design and program a microcontroller.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME386C: Microcontrollers LabB. Tech. 3rd Year (Semester – VI)




EXPERIMENTS1 Study Architecture of 8051 Microcontroller & Power on reset circuit2. (a) Write an assembly language program for adding eight 8-bit numbers. (b) Write an assembly language program for finding average of eight 8-bit numbers.3. (a) Write an assembly language program for finding maximum number from given 8-bit


ten numbers. (b) Write an assembly language program for arranging the given ten 8-bit numbers in ascending order.4. Write an assembly language program to Generate a square wave of 10kHz at P1.0 5. Write a program to transfer data from given memory block B1 to block B2.6. Interface LED and switch with microcontroller 8051 or PIC.7. Interface seven segment display with microcontroller 8051 or PIC.8. Interface LCD with microcontroller 8051 or PIC.9. Write an assembly language program for External program and test on hardware.10. Interface stepper motor with microcontroller 8051 or PIC.11. Interface DC motor with microcontroller 8051 or PIC and control speed using PWM.12. Write an assembly language program to transfer message serially.13. Write an assembly language program using interrupts to simultaneously create 7kHz and 500kHz square wave on P1.0 and P1.1 respectively.14. Design a mini project based on microcontrollerOUTCOMES On successful completion of the experiments, the student will be able to –1 Understand and apply the fundamentals of assembly level programming of microcontroller 2 Troubleshoot interactions between software and hardware. 3 Familiarize with interfacing of various peripheral devices.4 Improve programming logic and concepts.Note:At least ten experiments are to be performed in the semester. However, some more experiments may also be performed as designed & set by the concerned Institution as per the scope of the syllabus.


BME308C: Biological Control SystemsB. Tech. 3rd Year (Semester – VI)




Unit I


Introduction to state variable analysis of control systems: Introduction to state variable concept, definition of state variables, matrix representation of state equation, state transition equation, properties of transition matrix, relationship between state equations and higher order differential equations, state equation and transfer function, characteristics equation, Eigen values & Eigen vectors.

Unit IIModern control techniques: Transformation of state variables, controllability & observability of canonical form/ linear system, relationship among controllability, observability and transfer function.Introduction to biological control system: Dynamic systems and their control, modeling and block diagrams, the pupil control systems and its general structure &dynamic response characteristics, open & close loop systems instability, automatic aperture control.

Unit IIIMathematical modeling of the biological system: Thermoregulation of cold bloodedness & warm bloodedness, Anatomy of thermo-regulation, lumping & partial differential equations, heat transfer examples.Pharmacy kinetic model, urea distributionmodel, dissolution of drugs in solid form, distribution and accessibility of body water & tissue compartments, basis for zero & first order chemical kinetic behavior in the biological system.

Unit IVBiological receptors & other Physiological Control Systems: -Introduction, receptor characteristics, transfer function models of receptors, receptor and perceived intensity. Respiratory model & systems, cardiovascular control system, skeletal muscle servomechanism.TEXT BOOKS1. Automatic control systems- Benjamin C Kuo, John Wiley & Sons.2. Biological control systems- John H Milsum, McGraw-HillREFERENCE BOOKS1. Bio- Medical Engineering Principles- David O. Cooney, Taylor & Francis2. Biosimulation: simulation of living systems-Daniel. A. Beard, Cambridge University PressCOURSE OUTCOMES After the completion of the course the students will be able to1. Develop a mathematical model of biological control systems.2. Calculate the stability, controllability and observability of developed model.3. Design small controllable prototype of any physiological system.4. Predict and analyze the system response of biological control systems. Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




Professional Elective Courses – II

BME322C: Modelling & Simulation

B. Tech. 3rd Year (Semester – VI)L T P Credits Class Work : 25 Marks




Unit IMathematical Modeling of Biomedical Systems using Linear Models: Generalized system properties. Linear models of biomedical systems. Steady-state analysis. Time-domain analysis. Frequency-domain analysis. Stability analysis. Computer analysis and simulation using Matlab and Simulink.

Unit IIIdentification of Biomedical Control Systems: Identification methods for low-order dynamic models of patients. Identification of physiological systems: Anaesthesia, Diabetes mellitus. Parameter estimation of close loop drug delivery.

Unit IIIOptimization in Biomedical System Control: Application to models of biomedical systems: Optimization in systems with negative feedback; Single-parameter optimization; Constrained optimization. Anaesthesia and Diabetes Mellitus: Modelling, Model Analysis and Optimization

Unit IVNonlinearities in Biomedical Control Systems: Nonlinear versus linear systems. Nonlinear oscillators. Models of biomedical systems in Matlab and Simulink. Application of tools of modeling and simulation. Evaluation of various strategies for its operation. TEXT BOOKS1 System Identification: The theory for the user-Ljung, Lennart, Prentice Hall2. Simulation Modeling and Analysis - Averill.M.Law,McGraw-Hill3. Physiological control systems : analysis, simulation, and estimation-Khoo, Michael C.K, John Wiley & SonsREFERENCE BOOKS1 Applied Numerical Methods for Engineers using MATLAB and C - R.J. Schilling and S.L. Harris, S. Chand & Company2. Biosimulation: simulation of living systems, Daniel. A. Beard, Cambridge University Press3. Modelling Optimization and Control of Biomedical Systems- E. N. Pistikopoulos, I.Naşcu, E. G. Velliou, John Wiley

COURSE OUTCOMES After the completion of the course the students will be able to1. Analyze the behavior of a dynamical system.2. Use software tools & design models to understand its performance.3. Apply proper working methods of biomedical system modeling.4. Invent more advancement in modeling and simulation techniques.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering




BME324C: Biomedical Image ProcessingB. Tech. 3rd Year (Semester – VI)





Unit IDigital Image Processing Fundamentals: Digital Image Formation, Fundamentals Steps in Image Processing, Elements of Image Processing systems, Sampling and Quantization, Image Neighbors and Distance.Transforms used in Image Processing: Introduction to Fourier Transform, Discrete Fourier Transform and Some Properties of Fast Fourier Transform, Wavelet transforms.

Unit IIImage Enhancement: Basic gray level transformations, histogram processing, Smoothing operations, Edge Detection-derivative based operation, filtering in frequency domain, 2D-DFT, Smoothing frequency domain filters, Sharpening frequency domain filters, Homomorphic filteringImage Restoration:Background, Minimum Mean-square Error Restoration, Least square Error Restoration, Constrained Lease square Error restoration

Unit IIIImage Compression: Fundamentals, Image Compression Models, Error Free compression Techniques, Lossy compression Techniques Image Segmentation: Detection of Discontinuities, Pixel Board approach of segmentation, Multilevel Thresholding, Local Thresholding, Region based approach of segmentation.

Unit IVColour Image Processing: Colour Fundamentals, Colour Models, Examples of colour Image Processing, Pseudo colouring and colour Displays. Biomedical Application: Computer Tomography (Radon Transform & Back Projection Operator), MRI Images, Angiogram, Sonography including Doppler Technique, EEG image processingTEXT BOOKS1. Digital Image Processing –Rafel C. Gonalez and Richard E. Woods, Pearson Education2. Fundamentals of Digital Image Processing -A.K. Jain, Prentice HallREFERENCE BOOKS1. Digital Image Processing and Analysis- B. Chandaand D. Dutta Najumdar, PHI Learning2. Digital Image Processing for Medical Application- Geoff Dougherty, Cambridge University PressCOURSE OUTCOMES After the completion of the course the students will be able to1 demonstrate knowledge and understanding of the main categories of Image Processing operation 2 demonstrate the ability to evaluate and select image processing operations for a particular task3 critically evaluate alternative methods for performing a particular medical image analysis task4 understand how image processing techniques can be applied across medical imaging modalitiesNote:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering





BME326C: Hospital ManagementB. Tech. 3rd Year (Semester – VI)




Unit IChallenges of Health and Hospital Administration: Complexity of Hospitals created by ever increasing sophisticated diagnostic tools resulting into high cost (Need of Analysis and Planning), Declining Professional Ethics among specialist and other hospital staff. Analysis of Referral System, Analysis of Hospital Waste Management, Introduction of the latest Technologies to the Hospital Staff, Methods of reducing cost of health services, Analysis of the Quality of Hospital Services, Need of Streamlining the upkeep of Hospital through planning.

Unit IISocio-economic Development and Health Care and Nature of Health Care Administration: Goals and Aspects of Development and Their Inter-Relationship, Principles, Meaning and Objectives of Health Administration, Nature and Scope of Health Administration, Indicators Measuring Impact of Health Care Administration. Manpower Planning – Nature, Meaning and Ingredients of Manpower Planning, Development of Manpower Plans, National Health Policy.

Unit IIIFinancial Management and Cost Containment: Introduction to Management, Financial and Cost Management, Organization, Delegation of Powers/Authority and Fixation of Responsibility, Book Keeping, Charts of Accounts and Departmental Numbering, Material Management, Capital and Revenue Expenditure, Financial Statements and Reports, Budget and Budgetary Control, Cost Ascertainment and Cost Containment, Internal Control, Statistics and Management Information Systems.

Unit IVQuality Control and Quality Assurance in Health Care in a Hospital: Meaning and Need of Quality Control, Contents of Quality, Challenges to Setting Standards, Current Methods in Improving Quality.Hospital Waste Management: Classification, Amount of Hospital Waste, Hazards of Hospital Waste, Collection and Transportation of Hospital Waste, Disposal of Hospital Waste, Case Study.TEXT BOOKS1. Hospital Managerial Services by S.L.Goel & R. Kumar Deep, Deep & Deep Publication.2. Principles of Hospital Administration And Management- Ravi Bindra, Adroit PublisherREFERENCE BOOKS1.Hospital and Health Services Administration: Principals and Practice – Syed Amin Tabish, OUP IndiaCOURSE OUTCOMES After the completion of the course the students will be able to1. Understand basics about Health system and their services2. Apprehend the organization structure in hospitals 3. Gain knowledge about the regulation of health care waste management4. Understand the duties of technical personnelNote:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering



For students admitted in B. Tech. 1st Year (C-Scheme) in 2019 and all trailing students.


Examinations and evaluation of students shall be conducted as per guidelines of AICTE Examinations Reforms covering the entire syllabus. The students shall be made aware about the reforms.

BME328C: Principles of BioengineeringB. Tech. 3rd Year (Semester – VI)




Unit IHuman Physiological Fluid Mechanics, Blood Flow in the Microcirculation, and other Body Fluid Systems, Pulse and Wave Propagation in Blood Vessels, Mechanical Forces on Blood Vessels: Pressure, Stretch, and Shear Force, Viscoelasticity and Mechanical Properties of the Vessel, Vascular Remodeling and Tissue-Engineered Vascular Graft: Mechanical Factors

Unit IIMembrane Potentials & Cable Model, Hodgkin Huxley Model, Dielectric Properties of Cells & Biopolymers, Quantitative Physiology of Brain Blood Flow, Imaging Brain Blood Flow with Magnetic Resonance Imaging, Visual System Psychophysical Bioengineering: Matching warning signals to the properties of the eye and the visual nervous system, Visual Science Clinical Aspects, Geometrical Optics, Physical Optics and Microscopes, Optical Imaging

Unit IIIWireless Bioengineering, Imaging as an Inverse Problem, Human Molecular Imaging, Bioreactor Arrays, Bioheat Transfer, Applications to Cryosurgery

Unit IVStem Cell Research, Bioastronautics, Biological Molecular Structure and Function, Computational Modeling of Protein, Structure and Function, Molecular Structure/ Function of Neurodegeneration TEXT BOOKS1 Introduction to bioengineering-S.A. Berger, W. Goldsmith, E.R. Lewis, Oxford University PressREFERENCE BOOKS1 Biomedical Engineering and Design Handbook-Myer Kutz, McGraw-Hill COURSE OUTCOMES After the completion of the course the students will be able to1 Explain the principles and applications of mechanics in bioengineering2 Explain Principles, applications and techniques of human senses and their engineering.3 Understand imaging and wireless technologies in bioengineering.4 Understand computational methods in cell engineering.Note:1. In Semester Examinations, the examiner will set two questions from each unit (total 8 questions in all) covering






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