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Faculty of Pharmacy-Zagazig University Course Specifications 2012/2013

(Clinical Pharmacy Program)

First level – Semester 2

2012-2013

1


CONTENTS :

(1) Histology course specification ………………………….. …... 3

(2) Human rights course specification…………………………... 18

(3) Pharmaceutical Analytical Chemistry 1 course specification 28

(4) Pharmaceutical Organic Chemistry 2 course specification... 40

(5) Pharmacy Orientation course specification……………..…... 56

(6) Pharmacognosy 1 course specification ……………………… 69

(7) Physical Pharmacy course specification…………………….. 82

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COURSE SPECIFICATIONS

Histology

Second level – Semester 2

2012-2013

3


Course Specification of Histology (2012-2013)-----------------------------------------------------------------------------------------

University: Zagazig Faculty: Pharmacy

A- Course specifications:Program(s) on which the course is given: Clinical Pharmacy Program

Major or Minor element of programs: Major

Department offering the program: -------

Department offering the course: Histology department/ Faculty of Medicine

Academic year/ Level: First level/Semester 2

Date of specification approval: September 2012

B- Basic information:Title: Histology Code: MD203

Credit Hours:

Lectures: 2 hr/week

Practical: 2 hr/week

Tutorials: ---

Total: 3 hrs/week

C- Professional information: 1-Overall Aims of the Course:

Outline principles of cellular components, tissues, organs structure

and staining techniques.

Illustrate different types of microscopes and DNA structure.

Use proper medical terms, abbreviation and symbols of histology.

4


2-Intended Learning Outcomes of Histology (lLOs):

A- Knowledge and Understandinga1 Outline principles of cellular components structure and functions.a2 Illustrate principles of histological staining techniques.a3 Demonstrate different types of microscopes and their functions.

a4 Underline DNA and chromosome structure.

a5 Describe histological features of different tissues in normal and pathological conditions as well.

B- Professional and Practical skillsb1 Use proper medical terms, abbreviation and symbols of histology.b2 Construct a research study and analyze the results.C- Intellectual skillsc1 Evaluate both scientific and library based information.D- General and Transferable skillsd1 Write and present reports.

d2 Develop critical thinking, decision-making and problem-solving skills.

5


D- Contents:

Practical session (2hrs/week)

Lecture(2hrs/week)

Week No.

Projector slides for: 1- types of microscopes2- cell membrane 3- mitochondria4- Golgi bodies5- rough& smooth endoplasmic reticulum6- lysosomes

Types of microscopes (LM&EM)

Types of stains Membranous organoids (cell

membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes).

1

Projector slides for: 1- ribosomes2- centriolesc 3- cilia and falgella4- nucleus5- fat and liver glycogen

Non-membranous organoids Structure of the nucleus

2

Projector slides for: Chromosomes (krayotyping)

DNA structure Chromosomes structure Cell cycle

3

Projector slides for: 1-Simple epithelium2-Stratified epithelium

Epithelial tissues (structure, types, sites)

4

Projector slides for: 1-fat cells2- mast cells3- adipose c.t.4- areolar c.t.5- yellow elastic c.t6- tendon

Connective tissues and fibers (structure, types).

Connective tissues proper (structure, types).

5

Projector slides for: 1-hyaline and elastic cartilage2- compact

Histological structure of bone and cartilage.

6

6


decalcified,ground and spongy bonesPractical exam I

Projector slides for: blood film showing RBCs and leucocytes

RBCs and WBCs (histological structure, function)

Periodical exam

7

Projector slides for: skeletal, smooth and cardiac musclesActivity I

Histological structure of skeletal, smooth and cardiac muscles

8

Projector slides for: nerve trunk (H&E and osmic acid)

Histological structure of neurons, synapse, neurological cells and nerve endings

9

Projector slides for:1- aorta2- medium sized artery and vein3- basilar artery

Histological structure of arteries and veins

10

Projector slides for: 1- thymus2- tonsils3- spleen4- lymph node

Histological structure of thymus, tonsils, spleen and lymph node

11

Projector slides for: 1- fundus and pylorus2- small intestine3- large intestine

Histological structure of tongue, oesophagus, stomach, small and large intestine

12

Projector slides for: 1- liver2- pancreas3- salivary glands

Histological structure of liver, pancreas and salivary glands

13

Projector slides for: 1- kidney2- trachea3- lungActivity II

Histological structure of trachea, lung and kidney

14

7


Projector slides for: 1- pituitary gland2- supra-renal gland3- thyroid and paparathyroid glandsPractical exam II

Histological structure of pituitary, supra-renal, thyroid and parathyroid glands

15

E- Teaching and Learning Methods: Lectures (overhead projector, data show, board)

Practical sessions

Self learning (Activities…)

F- Student Assessment Methods 1. Periodical exam to assess: a1, a2,a3, a4, a52. Written exam to assess: a1, a2, a3, a4, a5, a6, c13. Practical exams to assess: b1,b2 4. Activities to assess: d1, d2

Assessment schedule:

Assessment (1): Written exam Week 16

Assessment (2): Activity Week 8, 14

Assessment (3): Practical exams Week 6,15

Assessment (4): Periodical exam Week 7

Weighting of Assessment:Assessment method Marks PercentageWritten exam 65 65%Practical exam and activities 25 25%Periodical exam 10 10%TOTAL 100 100%

8


G- Facilities Required for Teaching and Learning: Black (white) board, overhead projectors, Data show.

H- List of References:1- Course Notes: Handout

2- Essential Books (text books)

Ross M.H.& Pawlina W.: Histology: A Text and Atlas (Histology

(Ross)) (2010).

3- Recommended Books

Notes on histology for pharmacy students (prof.Dr.M.Fathy Saad )

--------------------------------------------------------------------------------------------

Course Coordinators: Prof. Dr. Gamal Abd Allah

Date: /9/2012

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http://www.amazon.com/Histology-Text-Atlas-Ross/dp/0781772001/ref=sr_1_1?s=books&ie=UTF8&qid=1345455922&sr=1-1&keywords=histology

http://www.amazon.com/Histology-Text-Atlas-Ross/dp/0781772001/ref=sr_1_1?s=books&ie=UTF8&qid=1345455922&sr=1-1&keywords=histology


Matrix I of Histology course

Course Contents

ILOs of Histology course

Knowledge and understanding

Professional and

practical skills

Intellectual skills

General and

transferable skills

Lectures a1 a2 a3 a4 a5 b1 b2 c1 d1 d2

1Types of microscopes (LM&EM), types of stains, membranous organoids (cell membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes). x x x

2 Non-membranous organoids, structure of the nucleus x 3 DNA structure, chromosomes structure, cell cycle x x 4 Epithelial tissues (structure, types, sites) x 5 Connective tissues and fibers (structure, types), connective tissues proper

(structure, types) x 6 Histological structure of bone and cartilage x 7 RBCs and WBCs (histological structure, function) x 8 Histological structure of skeletal, smooth and cardiac muscles x 9 Histological structure of neurons, synapse, neurological cells and nerve

endings x x 10 Histological structure of arteries and veins x 11 Histological structure of thymus, tonsils, spleen and lymph node x 12 Histological structure of tongue, oesophagus, stomach, small and large

intestine x 13 Histological structure of liver, pancreas and salivary glands x

10


14 Histological structure of trachea, lung and kidney x 15 Histological structure of pituitary, supra-renal, thyroid and parathyroid

glands x Practical sessions

1 Projector slides for:types of microscopes, cell membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes

x 2 Projector slides for: ribosomes, centriolesc,cilia and falgella,

nucleus, fat and liver glycogen x 3 Projector slides for: Chromosomes (krayotyping) x 4 Projector slides for: Simple epithelium,Stratified epithelium x

5 Projector slides for: fat cells, mast cells, adipose c.t., areolar c.t., yellow elastic c.t, tendon x

6Projector slides for: hyaline and elastic cartilage, compact decalcified, ground and spongy bonesPractical exam I x

7 Projector slides for: blood film showing RBCs and leucocytes x 8 Projector slides for: skeletal, smooth and cardiac muscles x 9 Projector slides for: nerve trunk (H&E and osmic acid) x 10 Projector slides for: aorta, medium sized artery and vein, basilar artery x 11 Projector slides for: thymus, tonsils, spleen, lymph node x 12 Projector slides for: fundus and pylorus, small intestine, large intestine x

11


13 Projector slides for: liver, pancreas, salivary glands x 14 Projector slides for: kidney, trachea, lung

Activity II x x x x

15

Projector slides for: pituitary gland, supra-renal gland,thyroid and paparathyroid glandsPractical exam II x

12


Matrix II of Histology National

Academic Reference Standards

NARS

Program ILOs

Course ILOs Course contents Sources

Teaching and learning methods

Method of assessment

Lecture Practical session

Self learning

Written exam

Practical exam

2.1

Principles of basic,

pharmaceutical, medical, social,

behavioral, management,

health and environmental

sciences as well as

pharmacy practice.

A2

a1

Types of microscopes (LM&EM), types of stains, membranous organoids (cell membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes).

Student book x x

Non-membranous organoids, structure of the nucleus

a2

Types of microscopes (LM&EM), types of stains, membranous organoids (cell membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes).

Student book x x

2.7

Principles of various

instruments and techniques

A 18 a3

Types of microscopes (LM&EM), types of stains, membranous organoids (cell membrane,

Notebook x x

13


including sampling,

manufacturing, packaging, labeling,

storing and distribution processes in

pharmaceutical industry

mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes).

2.11

Principles of body function in health and disease states

as well as basis of genomic and

different biochemical

pathways regarding their correlation with

different diseases.

A 16 a4DNA structure, chromosomes structure, cell cycle

Notebook x x

2.12

Etiology, epidemiology,

laboratory diagnosis and

clinical features of different diseases and

their pharmaco-therapeutic approaches

A19 a5

Epithelial tissues (structure, types, sites)

Student book x x

connective tissues and fibers (structure, types), connective tissues proper (structure, types) Histological structure of bone and cartilageRBCs and WBCs (histological structure, function)Histological structure of

14


skeletal, smooth and cardiac musclesHistological structure of neurons, synapse, neurological cells and nerve endingsHistological structure of arteries and veinsHistological structure of thymus, tonsils, spleen and lymph nodeHistological structure of tongue, oesophagus, stomach, small and large intestineHistological structure of liver, pancreas and salivary glandsHistological structure of trachea, lung and kidneyHistological structure of pituitary, supra-renal, thyroid and parathyroid glands

3.1

Use the proper pharmaceutical

and medical terms and

abbrevations and symbols in

pharmacy practice

B1 b1

Projector slides for:types of microscopes, cell membrane, mitochondria, Golgi bodies, rough& smooth endoplasmic reticulum and lysosomes Practical

Notes x xProjector slides for: ribosomes, centriolesc,cilia and falgella,nucleus, fat and liver glycogen

15


Projector slides for: Chromosomes (krayotyping)

3.11

Conduct research studies and analyze the

results

B13 b2

Projector slides for: Simple epithelium,Stratified epithelium

Practical Notes x x

Projector slides for: fat cells, mast cells, adipose c.t., areolar c.t., yellow elastic c.t, tendonProjector slides for: hyaline and elastic cartilage, compact decalcified, ground and spongy bonesProjector slides for: blood film showing RBCs and leucocytesProjector slides for: skeletal, smooth and cardiac musclesProjector slides for: nerve trunk (H&E and osmic acid) Projector slides for: aorta, medium sized artery and vein, basilar artery Projector slides for: thymus, tonsils, spleen, lymph nodeProjector slides for: fundus and pylorus, small intestine, large intestine Projector slides for: liver, pancreas, salivary glands

16


Projector slides for: kidney, trachea, lungProjector slides for: pituitary gland, supra-renal gland,thyroid and paparathyroid glands

4.14

Analyze and evaluate

evidence- based

information needed in pharmacy practice

C16 c1

Activity DNA structure,

chromosomes structure, cell cycle, Histological structure of neurons,

synapse, neurological cells and nerve endings

Student book,

essential book,

internet

x x x x x

5.9

Implement writing and presentation

skills

D10 d1 Activity Internet

x x

x

5.10

Demonstrate critical

thinking, problem-

solving and decision-making abilities

D11 d2 Activity Internet

x x x

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Human Rights


2012-2013

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اإلنسان حقوق مقرر توصيفالزقازيق كلية جامعة

الصيدلة : المقرر- مواصفات أ

: بكالوريو المقرر خاللها من يقدم التى البرامج أو الصيدلة سالبرنامج

األكلينيكيه : ً ثانويا للبرامج بالنسبة ثانويا أو رئيسيا عنصرا يمثل المقرر

: البرنامج عن المسئول العلمي --------------------------- القسم

: المقرر تدريس عن المسئول العلمي - القسم جامعة الحقوق كلية

الزقازيق. : األولى المستوي الدراسية .–السنة الثاني التيرم : سبتمبر التوصيف اعتماد .2012تاريخ

: ( األساسية( البيانات بالكود : : اإلنسان حقوق HU 201العنوان

المعتمدة : --- الساعاتأسبوعيا المحاضرات : ساعتانالعملي: ---

العملية : ---الدروس

األسبوع 2المجموع : في ساعة: ( المهنية( البيانات ج

1: للمقرر) العامة األهداف أهمية معرفة على قادرين الطالب يكون سوف المقرر إتمام عند

. الحقوق تلك حماية وكيفية المجتمع نحو وواجباته اإلنسان حقوق2: اإلنسان) حقوق لمقرر المستهدفة التعليمية النتائج

والفهم –أ المعرفةومصدرها ب يلم اإلنسان بحقوق .المقصود 1أ

.يعدد والجماعية الفردية اإلنسان حقوق أنواع 2أ.يشرح الحقوق هذه حماية كيفية 3أ

الذهنية- المهارات ج

19


اإلنسان . حقوق يدرك 1ج

. اآلخرين نحو بواجباته يلم ج2

حقوق مجال في اآلخرين سلوك تقييم على الطالب قدرات ينمياإلنسان.

ج3

والمنقولة- العامة المهارات د. الفريق أفراد كأحد بكفاءة يعمل 1د

الجماعية و الفردية الحقوق معرفة خالل من الفرد شخصية ينميلإلنسان. 2د

. المشكالت حل و القرارات اتخاذ و النقدي التفكير مهارات ينمي 3د

: المحتويات- د

المحاضرة األسبوع)2( األسبوع/ ساعة

مقدمة- 1اإلنسان- 2 بحقوق التعريفاإلنسان- (3 حقوق )1قانوناإلنسان- (4 حقوق تكملة) 2قانوناإلنسان- (5 حقوق تكملة) 3قانوناإلنسان- (6 حقوق قانون )1مصادراإلنسان- (7 حقوق قانون تكملة) 2مصادر

الدوري االمتحان8( فردية- ( اإلنسان حقوق أنواع9 ( جماعية- ( اإلنسان حقوق أنواعاإلنسان- (10 حقوق )1حمايةاإلنسان- (11 حقوق تكملة) 2حمايةالطبي- (12 المجال في اإلنسان حقوق )1تطبيقاتالطبي- (13 المجال في اإلنسان حقوق )2تطبيقاتالطبي- (14 المجال في اإلنسان حقوق )3تطبيقاتحره- 15 مناقشة و عامة مراجعة

: التعلم- و التعليم أساليب هـالمحاضرةالمناقشة

: - الطلبة تقييم أساليب و1- : أ يقيم الدوري أ 1االمتحان ج 2و ج 1و 2و

20


2- : أ يقيم التحريري أ 1االمتحان أ 2و ج 3و ج 1و ج 2و د 3و د 1و د 2و 3و

: التقييم الزمني الجدولالسابع األسبوع الدوري ):1تقييم ( االمتحانعشر السادس األسبوع التحريري ):2تقييم ( االمتحان

: التقييم ترجيحالمئوية النسب الدرجات التقييم طريقة

10% 10 الدوري االمتحان90% 90 التحريري االمتحان

100% 100 اإلجمالي

: التعلم- و للتعليم الالزمة التسهيالت ز1) ( ) : داتا- المرئي العرض جهاز و السوداء و البيضاء اللوحات للمحاضرات

شو).: المراجع- قائمة ي

1 : المقرر- ) مذاكرات اإلنسان ( حقوق الطالب )2012(كتاب

الدراسية- 2 الكتباإلنسان حقوق

مقترحة- 3 كتباإلنساني الدولي القانون

الخ- 4 انترنت، مواقع دورية، مجالتاإلنسان حقوق مجالت

. . : هاشم الرءوف عبد د أ المقرر منسق2012/ التاريخ: /

21


22


اإلنسان 1مصفوفة حقوق مقررحقوق لمادة المنشودة التعلم نتائج

اإلنسانالمقرر و محتويات عامة مهارات

تواصلية المهاراتالفكرية

و المعرفةالفهم

د3

د2 1د

ج3

ج2

ج1 3أ 2أ 1أ

x مقدمة 1

x اإلنسان بحقوق التعريف 2

x اإلنسان ( حقوق )1قانون 3

x اإلنسان ( حقوق تكملة) 2قانون 4

x اإلنسان ( حقوق تكملة) 3قانون 5

x اإلنسان ( حقوق قانون )1مصادر 6

x اإلنسان ( حقوق قانون تكملة) 2مصادر 7

x x ( فردية ( اإلنسان حقوق أنواع 8

x x ( جماعية ( اإلنسان حقوق أنواع 9

x x اإلنسان ( حقوق )1حماية 10

x x اإلنسان ( حقوق تكملة) 2حماية 11

x x x x x x x المجال في اإلنسان حقوق تطبيقات) 1الطبي ( 12

x x x x x x x المجال في اإلنسان حقوق تطبيقاتتكملة) 2الطبي ( 13

23


x x x x x x x المجال في اإلنسان حقوق تطبيقاتتكملة) 3الطبي ( 14

x x x x x x x حره مناقشة و عامة مراجعة 15

اإلنسان 2مصفوفة حقوق مقررأسلو ب

التقييم

التعليم أساليبالتعلم و

المصدر

محتوياتالمقرر

نتائج التعلمالمنش ودة

للمقرر

نتائج التعلمالمنش ودة

للبرنامج

المعايير األكاديمية المرجعية

)NARSالقومية (االمتحا

نالتحرير

ي

التعل م

الذاتي

الدرو س

العملية

المحاضرة

x x كتابالطالب مقدمة

1أ 1أ

العلوم مباديءو األساسية

الطبية و الصيدالنيةو االجتماعية و

اإلدارة و السلوكيةالعلوم و الصحة و

عن فضال البيئيةالصيدلة ممارسة

2.1x x كتابالطالب

بحقوق التعريفاإلنسان

x x كتابالطالب

حقوق قانون)1اإلنسان (

24



حقوق قانون )2اإلنسان (تكملة


حقوق قانون )3اإلنسان (تكملة


قانون مصادراإلنسان ( حقوق

1(


قانون مصادراإلنسان ( حقوق

تكملة) 2


حقوق أنواع( فردية ( اإلنسان

2أ

x x x كتابالطالب

حقوق أنواع اإلنسان

( جماعية(


حقوق تطبيقاتفي اإلنسان

الطبي ( المجال1 (



الطبي ( المجالتكملة) 2



الطبي ( المجال

25


تكملة) 3

x

x كتاب

الطالب وكتب

مقترحة

و عامة مراجعةحره مناقشة


حقوق حماية)1اإلنسان (

3أ 31أ

و المنظمة الشئونو الصيدلة قوانين

األخالقية المباديءو الصحية للرعاية

الصيدلة مهنة

2.21


حقوق حماية )2اإلنسان (تكملة

x

x كتابالطالب



x




x




x

x كتاب


مقترحة



حقوق أنواع( فردية ( اإلنسان

1ج

16ج

من مجموعة يحللمتعددة المعلومات

مجال في المصادرالصيدلة

4.14x x كتابالطالب


( جماعية(


حقوق أنواع( فردية ( اإلنسان 2ج

26




( جماعية(















3ج







x x كتاب


مقترحة


27





1د 4د كأحد بكفاءة يعملالفريق أفراد 5.3







x x كتاب


مقترحة





2د 8د

المهارات ينميالتي و اإلدارية

و التمويل تشملو التسويقالمبيعات

5.7







x x كتاب


مقترحة




الطبي ( المجال3د 11د

مهارات ينميو النقدي التفكيرو المشكالت حل

5.1O

28


1 (

القرارات اتخاذ







x x كتاب


مقترحة


29



Pharmaceutical Analytical Chemistry I

First level- Semester 2 2012-2013

30


Course Specification of Pharmaceutical Analytical Chemistry I for (2012/2013)

---------------------------------------------------------------------


A- Course specifications:Program(s) on which the course is given: Clinical pharmacy program



Department offering the course: Pharmaceutical Analytical Chemistry

Academic year / Level: First level / Semester 2

Date of specification approval: September 2012

B- Basic information:Title: Pharmaceutical Analytical Chemistry I Code: PC 205

Credit hours

Lectures :2 hrs/week

Tutorials: ---

Practical: 2 hrs/week

Total: 3 hrs/week

c- Professional information:

1-Overal1 Aims of the CourseAt the end of the course, the students will be able to:

Illustrate theories and mechanisms of neutralization, preciptimetry and gravimetric reactions.

Describe the major procedures for running a reaction and the ideal conditions for each one.

31


2-Intended Learning Outcomes of Pharmacutical Analytical

chemistry Course (lLQs)

A- Knowledge and Understanding

a1Illustrate theories and mechanisms of neutralization, preciptietric

and gravimetric reactions.

a2Describe the major procedures for running a reaction and the ideal

conditions for each one.

a3Demonstrate the methods of converting resulting analytical data

into concentrations

B- Professional and Practical skills

b1 Handle and dispose chemicals safely.

b2Apply neutralization, preciptietric and Gravimetric reactions in

determination of some inorganic and organic compounds

C- Intellectual skills

c1Interpret results obtained from different methods applied for

determination of different pharmaceutical mixtures.

c2 Convert obtained analytical results into concentrations

c3Decide the use of the most appropriate standardization method for

different compounds.

D- General and Transferable skillsd1 Work as member of team

d2 Adopt safety guidelines

d3 Manage time and perform a task within time limit.

32


D- Contents:

Week Lecture

(2 hrs/week)

Practical

(2hrs/week)

1 Theoretical bases of acid base

reactions and pH calculations

Safety guidelines

2 Acid base equilibrium and pH

calculations

Preparation of standard

solutions

3 Buffer solutions Standardization of strong

acids and bases

4 Neutralization indicators Determination of NaOH and

Na2CO3

5 Color determination of pH and

neutralization titration curves

Det. Of boric acid, borax and

their mixture

6 Application of neutralization reactions Det. Of sodium carbonate

and bicarbonate

7 Nonaqueous titrations

Periodical exam

Det. Of HCl/HAC mix. And

BaCl2

8 Introduction to gravimetric analysis Practical exam I

9 Contamination and its reduction Determination of calcium

10 Application of gravimetric analysis Determination of Iron

11 Types of solutions Presentation

12 colloids Activity

13 Theory of preciptimetry Determination of chloride

14 Solubility product rules Determination of iodide

33


15 Argentometric indicators Practical exam II

E- Teaching and Learning Methods Lectures (overhead projector, data show, board)

Practical sessions

Activity

F- Student Assessment Methods 1- Written exam to assess : a1,a2,a3,c1

2- Practical exam to assess : b1- b2, c1,c2,c3,d1,d2,d3

3- Oral exam to assess : a1,a2,a3,c1

4- Periodical exam to assess : a2,a3


Assessment (1): Practical exam 1 Week 8,15Assessment (3): written exam Week 16Assessment (4): Oral exam Week 16Assessment (5) Activity Week 12Assessment (6) Periodical exam Week 7

Weighting of AssessmentAssessment method Marks PercentageWritten exam 50 50%Practical exam 25 25%Periodical exam 10 10%Oral exam 15 15%TOTAL 100 100%

34


G- Facilities Required for Teaching and Learning:Black (white) board, overhead projectors, Data show and software.

G- List of References

1- Course Notes: Lecture notes and department notes

2- Essential Books (Text Books)G. Svehla "Vogel's Textbook of Quantitative Inorganic Analysis

including Elementary Instrumental Analysis" 4th edn, Longman Inc.,

New York (1978).

3- Recommended Books i- F. Rouessac, A. Rouessac "Chemical Analysis: Modern Instrumental

Methods and Techniques" 4th edn, John Wiley & Sons, Ltd., New York

(1998).

ii- Stuart A. Burman "Instrumentation in Analytical Chemistry"

American Chemical Society, Washington (1982).

4- Periodicals, Web Sites, etcAnalytical Letters Journal

Analyst Journal

Journal of pharmaceutical and biomedical analysis

Course Coordinators: Prof. Dr. Hanna Saleh

Head of department: Prof. Dr. Mohamed Elbolkiny

Date: القسم مجلس من المقرر توصيف إعتماد و مناقشة تمم 2012/ 9 / بتاريخ

35


36


Matrix I of Pharmaceutical Analytical Chemistry I

Course Contents

ILOs of the course

knowledge and

understanding

practical

skills

intellectual

skills

Transferable

and general

skills

Lecturesa1 a2 a3 b1 b3 c1 c2 c3 d1 d2 d3

1Theoretical bases of acid base reactions and pH calculations

x x2 Acid base equilibrium and pH calculations x3 Buffer solutions x4 Neutralization indicators x x5 Color determination of pH and neutralization titration curves x x

37


6 Application of neutralization reactions x7 Nonaqueous titrations x x8 Introduction to gravimetric analysis x9 Contamination and its reduction x x10 Application of gravimetric analysis x11 Types of solutions x x12 colloids x13 Theory of preciptimetry x x14 Solubility product rules x15 Argentometric indicators x x15 Safety guidelines x x16 Preparation of standard solutions x x x x x x

17 Standardization of strong acids and bases x x x x x

18 Determination of NaOH and Na2CO3 x x x x x

19 Det. Of boric acid, borax and their mixture x x x x x

20 Det. Of sodium carbonate and bicarbonate x x x

38


21 Det. Of HCl/HAC mix. And BaCl2 x x x x x

22 Determination of calcium x x x x x

23 Determination of Iron x x x x x

24 Presentation x x x x x

25 Activity x x x

26 Determination of chloride x x x x x

27 Determination of iodide x x x x x

39


Matrix II of Pharmaceutical Analytical Chemistry I

National Academic Reference Standards

NARS

Program

ILOs



Weighting of assessment

lecture

practical

session

self learnin

g

written

exam

practical

exam

oral

exam

periodical

exam

2.1

Principles of basic,

pharmaceutical, medical,

social, behavioral,

management, health and

environmental sciences

as well as pharmacy

practice.

A1 a1

Theoretical bases of acid base reactions and pH calculations

Theory of gravimetry Theory of

preciptimetry and solubility product rule

Colloids and solutions

notebook x x x x

2.3

Principles of different

analytical techniques

using GLP guidelines

and validation

procedures.

A7 a2 Buffer solutions and neutralization indicators

Color determination of pH and neutralization titration curves

Application of neutralization reactions

Nonaqueous titrations

NotebookReference

Web

x x x x

40


Titration curves and det. of E.P. in redox reactions

Application of gravimetric reactions

Titration curves and applications of preciptimetric reactions

2.17

Methods of biostatistical

analysis and

pharmaceutical

calculations

A17 a3

Theoretical bases of acid base reactions and pH calculations

Application of neutralization reactions

Nonaqueous titrations Titration curves and

determination of E.P. in redox reactions

Detection of E.P. in preciptimetric reactions

Gravimetric reactins

notebook x x x x

3.2

Handle and dispose

chemicals and

pharmaceutical

preparations safely

B2 b1 Safety guidelines Standardization of

strong acids and bases

Practical notebook x x

3.4

Extract, isolate,

synthesize, purify,

identify, and/or

standardize active

substances from different

origins.

B5 b2

Standardization of strong acids and bases

Det. Of boric acid, borax and their mixture

Det. Of sodium carbonate and bicarbonate

Det. Of HCl/HAC mix. And BaCl2

Det. Of calcium and magnesium mixture

Determination of calcium and iron


4.3 Apply qualitative and

quantitative analytical

C3 c1 c2


41


and biological methods

for QC and assay of raw

materials as well as

pharmaceutical

preparations

Determination of chloride and iodide

4.5

Select the appropriate

methods of isolation,

synthesis, purification,

identification, and

standardization of active

substances from different

origins.

C6 c3

Determination of mixtures as HCl/HAC and carbonate and bicarbonate


5.3Work effectively in a

team D3 d1 All practical sessions Activity

Practical notebook Web

x

5.6Adopt ethical, legal and

safety guidelines D7 d2

Safety guidelines Practical notebook x

5.8Demonstrate creativity

and time management

abilitiesD9 d3 All practical sessions

Activity

Practical notebook

Webx

42


43



Pharmaceutical Organic Chemistry -2


44


Course Specification of Pharmaceutical Organic

Chemistry-2 (2012/2013)

--------------------------------------------------------------------

-


A- Course specifications:Program(s) on which the course is given: Clinical Pharmacy program



Department offering the course: Pharmaceutical Organic Chemistry

Academic year Level: First level /Semester 2

Date of specification approval: October 2012B- Basic information:Title: Pharmaceutical Organic Chemistry -2 Code: PC 203

Credit hours:

Lectures: 2 hrs/week


Tutorials: ---

Total: 3 hrs/week


On completion of the course, students will be able to:

Acquire the fundamental bases of stereochemistry of organic compounds and the chemistry of carbohydrates, their identification, and their application in pharmaceutical compounds.

45


Understand the chemistry of aromatic heterocyclic compounds as well as their importance in the synthesis of drugs (in pharmaceutical industry).

Develop skills in terms of identification and synthesis of organic compounds including some drugs

2-Intended Learning Outcomes of the course (lLOs):

a-Knowledge and Understandinga1

Understand the basic principles of Stereochemistry of organic compounds and know the chemistry of Carbohydrates and their important chemical reactions.

a2 Appropriately name a given heterocyclic compounds and synthesize different aromatic heterocyclic compounds.

a3 Identify the functional groups in organic compounds and their use in some synthetic procedures.

b-Intellectual skillsb1 Identify the stereochemistry of organic compounds and their

reaction products.

b2 Correlate the chemistry of carbohydrates to their important role in biological sciences and pharmaceutical compounds.

b3 Suggest methods for synthesizing aromatic heterocyclic compounds of pharmaceutical interest.

b4 Correlate the structure of organic molecules with their chemical properties.

c-Professional and Practical skillsc1 Analyze the stereochemistry of organic compounds and their

chemical reactions.c2 Efficiently identify carbohydrate compounds and conduct

simple chemical synthetic reactions.c3 Use laboratory reagents adequately, safely and successfully.

d-General and Transferable skillsd1 Critical thinking.d2 Problem solvingd3 Integration of different fields of knowledge.d4 Team work.d5 Independent learning.

46


D-Content

Week Lecture (2hrs)

Practical (2hrs)

1 1- Stereochemistry*Definition, aim of study, classification *Structural isomerism

-Melting point determination-Crystalization

2 *Rotational isomerism*Geometrical isomerism

-Synthesis of Nitrobenzene

3 *.Optical isomerism- Synthesis of Nitro-naphthaleneActivity

4 * R and S, Enantiomers , Diastereomers* D, L and Erythro, threo Nomenclature

- Synthesis of m-Nitro-benzoic acid

5 2- CarbohydratesIntroductionClassification

-Synthesis of Picric acid-

6 Monosaccharide'si. Synthesisii.Cyclic structure of Monosaccharidesiii.Chemical reactions of Monosaccharides

-Synthesis of Monophenyl urea

7 *DisaccharidesI. Nomenclatureii. Chemical reactions of DisaccharidesPeriodical exam

- Synthesis of Dibenzal acetone- Practical exam

8 Polysaccharidesi.Nomenclatureii.Chemical reactions and determination of the type of glycosidic

- Synthesis of Tribromophenol

47


linkage.

9 3- Heterocyclic chemistryNomenclature of heterocyclic & fused heterocyclic compounds

- Identification of Carbohydrates-

Activity

10 Five membered ringFuran, Pyrrole&Thiophene.Reactions& Synthesis

- Synthesis of Glucosasone

11 Five membered ring with two nitrogensPyrazole& Imidazole Synthesis & Properties

-Revision lab for identification of unknown

12 Six-membered ringPyridine and its derivatives.Synthesis & Reactions.

-Revision lab for synthetic methods

13 Six-membered ring with two nitrogens.Pyrimidine, Pyrazine&PyridazineSynthesis & Properties

Final Practical Exam

14 Fused systemQuinoline, Isoquinoline,Indole and purinesSynthesis& chemistry

15 Heterocyclic compounds in Pharmaceutical Industry

16 Written exam

48


E- Teaching and Learning Methods: Lectures

Practical session

Self learning (internet search on some selected topics….)

6-Student Assessment methods: 1- Written exam to assess: a1, a2, a3, c1, c2

2- Practical exams to assess: b1, b2, b3, b4, d2, c2, c3

3- Activities to assess: d1, d2, d3, d4, d5

4- Periodical exam to assess: a1, a2


Assessment (1): Written exam Week 16Assessment (2): Practical exams Week 7,13Assessment (3): Activity Week 3,9Assessment (4): Periodical exam Week 7

Section I.01 Weighting of AssessmentAssessment method Marks PercentageWritten exam 50 50%Practical exam 25 25%Periodical exam 10 10%Oral exam 15 15%TOTAL 100 100%

G- Facilities Required for Teaching and Learning: Black (white) board, overhead projectors, Data show and software.

49


7-Rreferences &books

1-Alan.R.Katritzky, Christopher A. Ransden ,john.A.joule&viktor v. “ Handbook of Heterocyclic Chemistry ,3rd edition.2010.

2-John A.joule ,” Heterocyclic Chemistry” 5th edition .2010

3-Stereochemistry workbook , problems & solution 2006.

Course Coordinators: Prof. Dr. Eatedal Hassan Abd el-aal

Head of department: Prof. Dr. Eatedal Hassan Abd el-aal

Date: / / 2012 مجلس من المقرر توصيف إعتماد و مناقشة تمبتاريخ القسم

50


Matrix I of Pharmaceutical Organic Chemistry-2

Course Contents Knowledge and Understanding

Professional and practical skills

Intellectual skills

General and Transferable skills

Lectures a1 a2 a3 b1 b2 b3 b4 c1 c2 c3 d1 d2 d3 d4 d5

11- Stereochemistry*Definition, aim of study, classification *Structural isomerism

x x x

2 *Rotational isomerism*Geometrical isomerism x x x

3*.Optical isomerism x x x * activity x x x x

4 * R and S, Enantiomers , Diastereomers* D, L and Erythro, threo Nomenclature x x x

52- CarbohydratesIntroductionClassification

x x x x x

6

Monosaccharidesi. Synthesisii.Cyclic structure of Monosaccharidesiii.Chemical reactions of Monosaccharides

x x x x x

Periodic exam x x

7*Disaccharidesi.Nomenclatureii. Chemical reactions of Disaccharides

x x x x x 8 *.Polysaccharides

i.Nomenclatureii.Chemical reactions and determination of the type of glycosidic

x x x x x

51


linkage

9

3- Heterocyclic chemistryNomenclature of heterocyclic & fused heterocyclic compounds

x x x

*activity x x x x x10 Five membered ring

Furan, Pyrrole&Thiophene.Reactions& Synthesis x x x x 11 Five membered ring with two nitrogens

Pyrazole& Imidazole Synthesis & Properties x x x x

12Six-membered ringPyridine and its derivatives.Synthesis & Reactions.

x x x x

13Six-membered ring with two nitrogens.Pyrimidine, Pyrazine&PyridazineSynthesis & Properties

x x x x

14Fused systemQuinoline, Isoquinoline,Indole and purinesSynthesis& chemistry

x x x x

15 Heterocyclic compounds in Pharmaceutical Industry x x x x 16 Written Exam x x

Practical sessions

1 Melting point determinationCrystalization x

2 Synthesis of Nitrobenzene x3 Synthesis of Nitro-naphthalene x4 Synthesis of Nitro-Benzoic acid x5 Synthesis of picric acid x

52


6 Synthesis of Monophenyl urea x7 Synthesis of Dibenzalaceton

Practical exam x8 Synthesis of tribromophenol x9 Identification of carbohydrates x x10 Synthesis of Glucosasone x11 Revision lab for identification of unknown x12 Revision lab for synthetic methods

Practical exam x13 Final Practical Exam x14

53


Matrix II of Pharmaceutical Organic Chemistry-2 course

54


National Academic Reference

Standards NARS

Program ILOs


Teaching and learning methods Weighting of assessment

Lecture Practical session

Self learning

Written exam

Practical exam

Periodical exam

2.1 Principles of basic, pharmaceutical, medical, social,



sciences as well as pharmacy practice.

A1

a1

1- Stereochemistry*Definition, aim of study, classification *Structural isomerism

Student book

Essential books

x x x

2- CarbohydratesIntroductionClassification*.Polysaccharidesi.Nomenclatureii.Chemical reactions and determination of the type of glycosidiclinkage

a2 3- Heterocyclic chemistryNomenclature of heterocyclic & fused heterocyclic compounds

Five membered ringFuran, Pyrrole&Thiophene.Reactions& Synthesis

Five membered ring with two nitrogensPyrazole& Imidazole Synthesis & PropertiesSix-membered ringPyridine and its derivatives.Synthesis & Reactions.Six-membered ring with two nitrogens.Pyrimidine,

55


Pyrazine&PyridazineSynthesis & Properties

a3

Heterocyclic compounds in Pharmaceutical Industry

Student book

Essential books

x x x

2.5Principles of drug design ,developme

nt and synthesis

A9a2


Student book

Essential books

Internet

x x x

Five membered ring with two nitrogensPyrazole& Imidazole Synthesis & Properties

Student book

Essential books

x x

Six-membered ringPyridine and its derivatives.Synthesis & Reactions.

Student book

Essential books

x x x

Six-membered ring with two nitrogens.Pyrimidine, Pyrazine&PyridazineSynthesis & Properties

Student book

Essential books

x x x

Fused systemQuinoline, Isoquinoline,Indole and purinesSynthesis& chemistry

Student book

Essential books

x x x

56


3.4 Extract , isolate ,synthesize , purify ,identify ,and /or standardize active substances from different origins.

B6 b3


Practical notes

x

x


x xSix-membered ringPyridine and its derivatives.Synthesis & Reactions.

x x

57


Six-membered ring with two nitrogens. Pyrimidine, Pyrazine&PyridazineSynthesis & Properties

Fused systemQuinoline, Isoquinoline,Indole and purinesSynthesis& chemistry

4.5

Select the appropriate methods of

isolation ,synthesis .purification ,identi

fication ,and standardization of active substances

from different origins.

C6 c2


Student book

Essential books

x


x x

Six-membered ringPyridine and its derivatives.Synthesis & Reactions.

x xSix-membered ring with two nitrogens.Pyrimidine, Pyrazine&PyridazineSynthesis & Properties

Fused systemQuinoline, Isoquinoline,Indole

58


and purinesSynthesis& chemistry

5.8

Demonstrate creactivity and

time management abilities

D9 d3

Revision lab for identification of unknown

Internet

x x

Revision lab for synthetic methods

5.10

Implement writing and

thinking ,problem solving and

decision-making abilites

D11

d1

activity

Practical notes

x

x


x

x

d2


activity

Practical Exam

59


60



Pharmacy Orientation


61


Course Specification of Pharmacy Orientation for (2012/2013)

-----------------------------------------------------------------------





Department offering the course: Pharmaceutics department


Date of specification approval: October 2012

B- Basic information:Title: Pharmacy Orientation Code: PT 202

Credit hours:


Practical: -----

Tutorials: ---

Total: 2 hrs/week



Illustrate the different principles of pharmacy orientation and medical terminology

62


2-Intended Learning Outcomes of Pharmacy Orientation (lLOs):


a1 Define different principles of pharmacy orientation

a2Mention the principles of different sciences in medical terminology


c1 Consider the definitions of different sciences and basics

63


D- Contents:

Lecture (2hrs/week)

Week No.

Pharmacy- Pharmacist- Drug1

Pharmacy education.2

-Departments of Faculty of Pharmacy- Pharmaceutical Organizations

3

Drug information- Pharmacopeias. Formularies4

Functions of Pharmacists - Dosage Forms.5

- Prefix pertaining to numbers6

Periodical exam7

- Prefix pertaining to colour and directions- Prefix pertaining to size and comparison

8

-Roots (examples), Suffix (examples).-Pharmacy terminology, Pharmacy-Dosage Regimen, Drug products. Dosage range. Loading and maintenance dose, LADME system, Intra- and extravascular administration.

9

-Ethics in Pharmacy- Code of ethics.-Rational use of drugs.

10

-Essential Drug list.-Self-care and self-medication, the role of pharmacists in it.-Standards of Practice, Regulations-The role of national and international organizations.

11

Disintegration- Dissolution- Bioavailability- Batch number- Manufacture- Production- Stability- Expiration date- Storage conditions.

12

Abrasive- Absorbent- Antacid- Anti-inflammatory- Anthelmentics- Antiamebic- Anti bacterial.

13

- Antidotes- Anti epileptics - Antihypertensive- Anti-mfectives- Antimalarials- Antipyretics- Antirheumatics- Antivirals.- Coagulants- Contraceptives- Antitussives- Bronchodilators- Systemically acting drugs

14

History of pharmacy15

64


E- Teaching and Learning Methods: Lectures

F- Student Assessment Methods: 1-Periodical exam to assess: a1, a2, c12-Written exam to assess : a1, a2, c1

Assessment schedule:Assessment (1): Periodical exam Week 7Assessment (2): Written exams Week 16

Section I.02 Weighting of AssessmentAssessment method Marks PercentageWritten exam 90 90%Periodical exam 10 10%TOTAL 100 100%


H- List of references:1- Course Notes:

2- Recommended books

Pharmacy: An Introduction to the Profession L. Michael Posey, 210, 2008

Pharmacy: What It Is and How It Works, Third Edition (Pharmacy

Education Series) William N. Kelly, 488, 2011.

Orientation in Pharmacy Ralph Clark ,181, 1961

--------------------------------------------------------------------------------------------

65

http://www.amazon.com/s/ref=ntt_athr_dp_sr_1?_encoding=UTF8&field-author=Ralph%20Clark&ie=UTF8&search-alias=books&sort=relevancerank

http://www.amazon.com/William-N.-Kelly/e/B001JSD7FC/ref=ntt_athr_dp_pel_1

http://www.amazon.com/L.-Michael-Posey/e/B001JS0W3W/ref=ntt_athr_dp_pel_1


Course Coordinators: Prof.Dr / Hanaa Abdel Fattah El ghamry

Head of department: Prof.Dr / Mahmoud Abdel Ghany Mahdy

Date: القسم مجلس من المقرر توصيف إعتماد و مناقشة تم2012/ 10 / بتاريخ

66


Matrix I of Pharmacy Orientation

Course contents

ILOs Knowledge

and understanding

Intellectual skills

a1 a2 c1 Lectures1 Pharmacy- Pharmacist- Drug x x2 Pharmacy education. x x

3-Departments of Faculty of Pharmacy- Pharmaceutical Organizations x x

4 Drug information- Pharmacopeias. Formularies x x5 Functions of Pharmacists - Dosage Forms. x 6 Word Parts [Prefix- Suffix- Root]. x 7 Prefix pertaining to numbers x 8 - Prefix pertaining to colour and directions

- Prefix pertaining to size and comparison x x

9

-Roots (examples), Suffix (examples).-Pharmacy terminology, Pharmacy-Dosage Regimen, Drug products. Dosage range. Loading and maintenance dose, LADME system, Intra- and extravascular administration.C15:C22 x x

10

-Ethics in Pharmacy- Code of ethics.-Rational use of drugs. x x

67


11

-Essential Drug list.-Self-care and self-medication, the role of pharmacists in it.-Standards of Practice, Regulations-The role of national and international organizations. x x

12

Disintegration- Dissolution- Bioavailability- Batch number- Manufacture- Production- Stability- Expiration date- Storage conditions. x

13Abrasive- Absorbent- Antacid- Anti-inflammatory- Anthelmentics- Antiamebic- Anti bacterial. x x

14

- Antidotes- Anti epileptics - Antihypertensives- Anti-mfectives- Antimalarials- Antipyretics- Antirheumatics- Antivirals.- Coagulants- Contraceptives- Antitussives- Bronchodilators- Systemically acting drugs x x

15 History of pharmacy x x x

68


Matrix II of Pharmacy Orientation


NARS

Program ILOs



Method of assessment

Lecture Self learning

Written exam

2.1 Principles of basic,




sciences as well as pharmacy

practice.

A2 a1Pharmacy- Pharmacist- Drug Student book x x

Pharmacy education. Student book x x-Departments of Faculty of Pharmacy- Pharmaceutical Organizations

Student book

Essential books

x x

Drug information- Pharmacopeias. Formularies

Student book

Essential books

x x

Functions of Pharmacists - Dosage Forms. Student book x xWord Parts [Prefix- Suffix- Root]. Student book x xPrefix pertaining to numbers Student book x x- Prefix pertaining to colour and directions- Prefix pertaining to size

Student book x x

69


and comparison

a2

-Roots (examples), Suffix (examples).-Pharmacy terminology, Pharmacy-Dosage Regimen, Drug products. Dosage range. Loading and maintenance dose, LADME system, Intra- and extravascular administration.C15:C22

Student book x x


Student book x x-Essential Drug list.-Self-care and self-medication, the role of pharmacists in it.-Standards of Practice, Regulations-The role of national and international organizations.

Student book x x


Student book x x


Student book x x

- Antidotes- Anti epileptics - Antihypertensives- Anti- Student book x x

70


mfectives- Antimalarials- Antipyretics- Antirheumatics- Antivirals.- Coagulants- Contraceptives- Antitussives- Bronchodilators- Systemically acting drugs

History of pharmacy Student book x x

4.1

Apply pharmaceutical

knowledge in the formulation of

safe and effective medicines as well as in dealing with new drug delivery

systems.

C1 c1

Pharmacy- Pharmacist- Drug x x

Pharmacy education. x x-Departments of Faculty of Pharmacy- Pharmaceutical Organizations

x x

Drug information- Pharmacopeias. Formularies

x x- Prefix pertaining to colour and directions- Prefix pertaining to size and comparison

x x

71


-Roots (examples), Suffix (examples).-Pharmacy terminology, Pharmacy-Dosage Regimen, Drug products. Dosage range. Loading and maintenance dose, LADME system, Intra- and extravascular administration.C15:C22


x x

-Essential Drug list.-Self-care and self-medication, the role of pharmacists in it.-Standards of Practice, Regulations-The role of national and international organizations.

x x


x x


x x

72


- Antidotes- Anti epileptics - Antihypertensives- Anti-mfectives- Antimalarials- Antipyretics- Antirheumatics- Antivirals.- Coagulants- Contraceptives- Antitussives- Bronchodilators- Systemically acting drugsHistory of Pharmacy

x x

73



Pharmacognosy 1


2012-201

74


Course Specification of Pharmacognosy I (2012-2013)

-------------------------------------------------------------------------------------------------------

University : Zagazig Faculty : Pharmacy

A- Course specifications:Program (s) on which the course is given : Clinical Pharmacy

Major or Minor element of programs : Major

Department offering the program : -------

Department offering the course : Pharmacognosy department

Academic year Level : First year /Second term

Date of specification approval : October 2012

B- Basic information: Title: Pharmacognosy 1 code: PG202

Credit Hours: ---

Lectures : 2 hrs/week

Practical : 2 hrs/week

Tutorials : ---

Total : 3 hrs/week

C- Professional information 1- Overall aim of the course:


Describe Morphological, Histological characters and uses of

medicinal flowers, barks, wood and herbs as well as Identification

of different active constituents and adulteration.

Examine and determine the active constituents of the studied

drugs.

75


Intended Learning Outcomes of Pharmacognosy 1 (ILOs) :


a1Illustrate morphological and Histological characters and uses of medicinal

flowers, barks, wood and herbs

a2 Identify adulteration of different medicinal flowers, barks, wood and herbs.

a3Demonstrate different active constituents of medicinal flowers, barks,

wood and herbs.

B- Professional and Practical skillsb1 Handel and dispose chemicals in a safe way.

b2 Handle equipments effectively

b3 Examine drugs of plant origin in entire and powdered form.

b4 Determine the active constituents of the studied drugs.

C- Intellectual skillsc1 Adapt GLP and safety guidelines in the lab.

c2 Differentiate between drugs in entire and powdered form.

c3 Investigate active constituents of different drugs.

D- General and Transferable skillsd1 Work as a member of a team.

d2 Manage time and plan of work.

d3 Write and present reports.

d4 Develop critical thinking and make a decision.

76


D. Contents

Practical session (2hrs/lab)

Lecture contents (2hrs/lecture)

Week No.

Laboratory safety measures Dealing with microscope.

General introduction for what will be taught all over the term

Introduction for the flowers and giving the students the possible references, web sites, text books.

1

Description of clove flower Including Macro- and micro-morphological study for entire drug.

Rest of introduction of flower.

2

Histology of powdered clove.

Description of clove flower Including Macro- and micro-morphological study for entire drug and for powdered clove.3

German chamomile flower macro-, and Micro-morphology, powders and chemical identification.

Chamomile (German and Roman) and calendula flowers macro-and, Micro-morphology of the entire and powdered drugs, chemical identification.

4

Santonica flowers macro-and, micro-morphology, powder and chemical identification.

Activity

Rest of flower drugs-, uses-, active constituents, pharmaceutical preparations.5

Practical exam1 General introduction of bark6 Cinnamon bark macro-and

Micro-morphology, powder and chemical identification.

Rest of the introduction and cinnamon bark: macro-and; micro morphology -, powder and chemical identification.

Periodical exam.

7

Cassia barks (Morphology, histology, powder and chemical test, when it is possible.

Cinchona in details: macro-and; micro-morphology - powder and chemical identification.

8

Cinchona barks (Morphology, histology for entire drug powder and chemical test when it is possible.

Cascarilla, quillaia, and canella bark (Morphology, histology, powder and chemical test when it is possible.9

Morphological demonstration for all barks

Cascara and frangula in details: macro-morphology; micro-morphology powder and chemical identification.

10

77


Revision for powdered barks (Cinnamon, Cassia and cinchona).

Rest of the taught barks.11

Quassia wood: Macro- and micro-morphology of entire wood.

Galls: Macro-morphology and micro-morphology of entire drug.

Introduction to wood12

Hyoscymusmuticus herb: Macro- and micro-morphology of entiredrug

Galls: Macro-morphology of entire wood; micro-morphology-, Powder; chemical identification

13

Mentha: Macro- and micro-morphology of Powder and chemical identification

Herbs introduction14

Practical exam 2 Official and nonofficial herbs15

E- Teaching and Learning Methods: Lectures.

Practical session.

Self learning (Activities, internet search).

F- Student Assessment Methods:1. Periodical exam to assess: a1, a3, c2 and c3

2. Written exams to assess: a1, a2, a3, c2 and c3

3. Practical exams to assess: b1, b2,b3, b4,c1 and d1

4. Oral exam to assess: a1, a2, a3, c2 and c3

5. Activities to assess: d1, d2, d3 and d4Assessment schedule:

Assessment (1): Written exam Week 16

Assessment (2): Practical exams Week 6, 15.

Assessment (3): Oral exam Week 16

Assessment (4): Activity Week 5

Assessment (5): Periodical exam Week 7

Weighting of Assessment

78


Assessment method Marks Percentage

Written exam 50 50%

Practical exam 25 25%

Oral exam 15 15%

Periodical exam 10 10%

TOTAL 100 100%

G- Facilities Required for Teaching and Learning: For lectures: Black (white) boards, overhead projectors, data show.

For Labs: Chemicals, glassware, instruments, digital balances and

water baths.

H- List of References :1-Course Notes: Student book of Pharmacognosy I

approved by pharmacognosy department (2012).

2 -Text Books:

Textbook of Pharmacognosy, 5t" Ed., T.E.Wallis(1967).

Trease and Evans, Pharmacognosy, 15t" Ed., Saunders

Company, Nottingham,U.K., Willium Charles Evans (2003).

-----------------------------------------------------------------------------------------

Course Coordinator : Prof Dr/AfafElsyedHead of department : Prof. Dr. Samih El-DahmyDate: القسم مجلس من المقرر توصيف إعتماد و مناقشة تم

2012/ 10 / بتاريخ

79


Matrix 1 of Pharmacognosy I

Course Contents

ILOs of Pharmacognosy I

knowledge and understanding

professional and practical skills

intellectual skills

Transferable and general

skillsa1x x x

a6 b1 b2 b3 b4 c1 c2 c3 d1 d2 d3 d4

9 General introduction for what will be taught all over the term. x x x x

2 Introduction for the flowers and giving the students the possible references, web sites, text books. x x x x

3 Rest of introduction of flower. x x x x 4 Description of clove flower Including Macro- and micro-

morphological study for entire drug and for powdered clove. x x x x

5Chamomile (German and Roman) and calendula flowers macro-and, Micro-morphology of the entire and powdered drugs, chemical identification.

x x x x

6 Rest of flower drugs, uses, active constituents, pharmaceutical preparations. x x x x

7 General introduction of bark x x x x

8 Rest of the introduction and cinnamon bark: macro-and; micro morphology -, powder and chemical identification. x x x x

11 Cinchona in details: macro-and; micro-morphology - powder and chemical identification. x x x x

80


x

x x

12 Cascarilla, quillaia, and canella bark (Morphology, histology, powder and chemical test when it is possible. x x x x

13 Cascara and frangula in details: macro-morphology; micro-morphology powder and chemical identification. x x x x

14 Rest of the taught barks. x x x x Introduction of wood x x x x Galls: Macro-morphology of entire wood; micro-morphology-,

Powder; chemical identification x x x x 15 Herbs introduction x x x x 16 Official and nonofficial herbs x x x x 17 Laboratory safety measures x x 18 Dealing with microscope. x x 19 Description of clove flower Including Macro- and micro-

morphological study for entire drug. x x x 20 Histology of powdered clove x x x 26 German chamomile flower macro-, and Micro-morphology,

powders and chemical identification x x x 27 Santonica flowers macro-and, micro-morphology, powder and

chemical identification. x x x 30 Cinnamon bark macro-and Micro-morphology, powder and chemical

identification. x x x 35 Cassia barks (Morphology, histology, powder and chemical

test, when it is possible. x x x 38 Cinchona barks (Morphology, histology for entire drug powder

and chemical test when it is possible. x x x

81


x x x

39 Morphological demonstration for all barks x x x 40 Quassia wood: Macro- and micro-morphology of entire wood. x x x 41 Galls: Macro-morphology and micro-morphology of entire

drug. x x x 42 Hyoscymus muticus herb: Macro- and micro-morphology of

entire drug x x x 42 Mentha: Macro- and micro-morphology of Powder and

chemical identification x x x

45 Activity (net search). x x x x

Matrix II of Pharmacognosy I


Program

Course

Course contents Sources

Teaching and learning


82


NARS ILOs ILOs methods

lecture

practical

session

self learni

ng

written

exam

practical

exam

oral exam

periodical exam

2.1 Principles of basic, pharmaceutical, medical, social, behavioral, management, health and environmental sciences as well as pharmacy practice.

A2

a1

General introduction for what will be taught all over the term.

Book note x x x x

Introduction for the flowers and giving the students the possible references, web sites, text books.Rest of introduction of flower.

Description of clove flower Including Macro- and micro-morphological study for entire drug and for powdered clove.Chamomile (German and Roman) and calendula flowers macro-and, Micro-morphology of the entire and powdered drugs, chemical identification.Rest of flower drugs, uses, active constituents, pharmaceutical preparations

a2 General introduction of bark Book note

x x x xRest of the introduction and cinnamon bark: macro-and; micro morphology -, powder and chemical identification.

83


Cinchona in details: macro-and; micro-morphology - powder and chemical identification.Cascarilla, quillaia, and canella bark (Morphology, histology, powder and chemical test when it is possible.

Cascara and frangula in details: macro-morphology; micro-morphology powder and chemical identification.

Rest of the taught barks.

a3

Introduction of wood Book note

x x xGalls: Macro-morphology of entire wood; micro-morphology-, Powder; chemical identification

a4Herbs introduction Book

note x x xOfficial and nonofficial herbs

a5Identify adulteration of different plant organs using microscope and chemical tests.

Book note x x x

2.3

Principles of isolation, synthesis, purification, identification, and standardization methods

A8 a6Study the active constituents of medicinal flowers, barks, woods and herbs.

Book note x x x x

84


of pharmaceutical compounds.

3.2

Handle and dispose chemicals and pharmaceutical preparations safely

B2b1 Safety measures lab Practical

note x

b2 Dealing with microscope Practical note x

3.4

Extract, isolate, synthesize, purify, identify, and/or standardize active substances from different origins.

B4

b3Examine the entire and powdered forms of different medicinal flowers, barks, wood and herbs.

Practical note x

b4identification of different secondary metabolites using chemical tests

Practical note x

4.2

Comprehend and apply GLP,GPMP, GSP and GCP guidelines in pharmacy practice

C2 c1 Safety measures lab. Practical note x

4.5 Select the appropriate methods of isolation, synthesis, purification, identification, and standardization of active substances from different origins.

C6

c2

Differentiate between drugs obtained from different medicinal flowers, barks, wood and herbs in entire and powdered form.

book note x x x x

c3 Study the active constituents of medicinal flowers, barks, wood and herbs.

book note

x x x x

85


5.3 Work effectively in a team D3 d1 activity Internet

research

x

5.8

Use numeracy, calculation and statistical methods as well as information technology tools

D8 d2 activity Internet research

x

5.9Demonstrate creativity and time management abilities

D.9 d3 activity Internet research

x

5.10 Implement writing and presentation skills D10 d4 activity Internet

research

x

86



Physical Pharmacy


87


Course Specification of Physical Pharmacy for (2012/2013)

------------------------------------------------------------------------





Department offering the course: Pharmaceutics department


Date of specification approval: October 2012

B- Basic information:Title: Physical pharmacy Code: PT 201

Credit hours:



Tutorials: ---

Total: 3 hrs/week



Illustrate the principles of pharmaceutical sciences Perform various laboratory tests for analysis of different samples.

88


2-Intended Learning Outcomes of Physical Pharmacy (lLOs):


a1 Mention the principles of physical pharmacy

a2 illustrate the rheology of pharmaceutical dosage forms

a3 Mention types of flow

a4 Summarize surface and interfacial phenomena

a4 illustrate solubility and dissolution rates

a5 Define solutions and mention their properties

a6 Summarize disperse systems

B- Professional and Practical skills

b1 Calculate the viscosity of liquids

b2 Calculate the surface tension of liquids

b3 Calculate the percentage of adsorbed substances

b4 Calculate the solubility of certain substances


c1 Assess properties of different disperse systems

D- General and Transferable skillsd1 explain different types of flow

89


D- Contents:

Practical session (2hrs/week)

Lecture (2hrs/week)

Week No.

Determination of viscosity of liquids (1)Principles of physical pharmacy

1

Determination of viscosity of liquids (2)Principles of physical pharmacy

2

Solving problem on viscosityThe rheology of pharmaceutical dosage forms

3

Determination of surface tension of liquids (1)Types of flow

4

Determination of surface tension of liquids (2)and lab evaluationSurface and interfacial phenomena

5

Practical exam-1Surface and interfacial phenomena6

Determination of percentage of adsorbed substances (1)Periodical exam

7

Determination of percentage of adsorbed substances (2)Solubility and dissolution rate

8

Determination of solubility of certain substances (1)Solubility and dissolution rate

9

Determination of solubility of certain substances (2)Solutions and their properties

10

General revisionsolutions and their properties11General revisionDisperse systems12Practical exam-2 Disperse systems13

Open discussion14-Revision15

E- Teaching and Learning Methods:

90


Lectures

Practical session

F- Student Assessment Methods: 1-Periodical exam to assess: a1 ,a2 ,a3 ,a4 ,d1

2-Written exam to assess: a1 ,a2 ,a3 ,a4 ,a5 ,a6 ,a7,c1 ,d1 3-Practical exams to assess: b1 ,b2 .b3 ,b4 4-Oral exam to assess: a1 ,a2 ,a3 ,a4 ,a5 ,a6 ,a7,c1 ,d1Assessment schedule:

Assessment (1): Written exam Week 16Assessment (2): Practical exams Week 6 ,13Assessment (3): Oral exams Week 16Assessment (4): Periodical exam Week 7

Section I.03 Weighting of AssessmentAssessment method Marks PercentageWritten exam 50 50%Practical exam 25 25%Oral exam 15 15%Periodical exam 10 10%Total 100 100%


H- List of references:1- Course Notes:

2- Recommended books

Physical Pharmacy: Physical Chemical Principles in the Pharmaceutical

Sciences, Alfred N. Martin,622, 1993

Martin's Physical Pharmacy and Pharmaceutical Sciences

Patrick J. Sinko, 672, 2010

91

http://www.amazon.com/Alfred-N.-Martin/e/B001H6ETA8/ref=ntt_athr_dp_pel_1


Physical Pharmacy Dr. U. B. Hadkar, 314, 2007

--------------------------------------------------------------------------------------------

Course Coordinators: Prof.Dr / Mahmoud Abdel Ghany Mahdy

Head of department: Prof.Dr / Mahmoud Abdel Ghany Mahdy

Date: القسم مجلس من المقرر توصيف إعتماد و مناقشة تم2012/ / بتاريخ

92

http://www.amazon.com/s/ref=ntt_athr_dp_sr_1?_encoding=UTF8&field-author=Dr.%20U.%20B.%20Hadkar&ie=UTF8&search-alias=books&sort=relevancerank


Matrix I of Physical Pharmacy

Course contents

ILOs of Physical Pharmacy course

Knowledge and undestanding Professional and practical skills

Intellectual skills

General and transferable skills

a1 a2 a3 a4 a5 a6 a7 b1 b2 b3 b4 c1 d1 Lectures1 Principles of physical pharmacy x 2 The rheology of pharmaceutical dosage forms x 3 Types of flow x x4 Surface and interfacial phenomena x 5 Surface and interfacial phenomena x 6 Solubility and dissolution rate x 7 Solutions and their properties x 8 Disperse systems x x

Practical sessions9 Determination of viscosity of liquids (1) x x

10 Determination of viscosity of liquids (2) x x11 Solving problem on viscosity x 12 Determination of surface tension of liquids (1) x x13 Determination of surface tension of liquids (2) x 14 Determination of percentage of adsorbed substances (1) x x

93


15 Determination of percentage of adsorbed substances (2) x 16 Determination of solubility of certain substances (1) x x 17 Determination of solubility of certain substances (2) x x

Matrix II of Physical Pharmacy

NARS program ILOS

Course ILOS

Course content Sources



lecture practical session

written exam

practical exam

oral exam

periodical exam

2.1 Principles of basic,



health and environmental sciences as

well as pharmacy practice.

A2 a1

Principles of physical pharmacy

notebook x x x x

a2

The rheology of pharmaceutical dosage forms

notebook x x x x

a3 Types of flow notebook x x x x

a4 Surface and interfacial phenomena

notebook x x x x

94


a6 solutions and their properties notebook x x x

a7 Disperse systems notebook x x x x

Solubility and dissolution rate

notebook x x x notebook x x x x

3.8 Apply techniques used

in operating pharmaceutical equipment and

instruments

B10

b1

Determination of viscosity of liquids (1)

notebook x x

Determination of viscosity of liquids (2)

notebook x x

b2

Determination of surface tension of liquids (1)

notebook x x

Determination of surface tension of liquids (2)

notebook x x

b3

Determination of % of adsorbed substances (1)

notebook x x

95


Determination of % of adsorbed substances (2)

notebook x x

b4

Determination of solubility of certain substances (1)

notebook x x

Determination of solubility of certain substances (2)

notebook x x

4.5 Select the appropriate methods of isolation, synthesis,

purification, identification,

and standardization

of active substances from different origins

C6 c1

Determination of surface tension of liquids Determination of % of adsorbed substances

notebook x x x

5.4 Use

numeracy, calculation and

statistical methods as well as information

technology tools

D5 d1 Types of flow notebook x x x

96


97

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