EDUCATIONAL OBJECTIVES At the completion of this activity, participants should be able to: • Review cytomorphologic features of common cystic neck lesions in adults • Recognize common and uncommon tumors that metastasize to lung • Identify and describe diagnostic pitfalls in the evaluation of gynecologic (liquid based) specimens relating to glandular and rare lesions • Evaluate and assess aspirate samples from pancreatic solid lesions • Understand the rationale and aims for the recent standardized terminology systems of Bethesda-Gyn, Paris and Milan • Enumerate the helpful diagnostic clues in the differential diagnoses of thyroid conditions • Discuss pitfalls and differential diagnosis of melanoma cytology • To understand the importance of a Quality Assurance (QA) and Quality Control (QC) in a cytopathology laboratory • Recognize benign/reactive entities that could potentially mimic malignant lung tumors • Understand the application of cytology for molecular diagnosis and its indication in lung cancer 2018 Cyto-econference Chair Michael J. Thrall, MD Cytopathology Fellowship Director Houston Methodist Hospital Houston, Texas American Society of Cytopathology [email protected](302) 543-6583 Register online at cytopathology.org WEBINARS EARN 2 CME/CMLE – 2 SAM CREDITS PER WEBINAR #asceconf Follow us and continue the discussion!
Transcript
EduCatIonal objECtIvEs
At the completion of this activity, participants should be able to:
• Review cytomorphologic features of common cystic neck lesions in adults• Recognize common and uncommon tumors that metastasize to lung• Identify and describe diagnostic pitfalls in the evaluation of gynecologic
(liquid based) specimens relating to glandular and rare lesions• Evaluate and assess aspirate samples from pancreatic solid lesions• Understand the rationale and aims for the recent standardized terminology
systems of Bethesda-Gyn, Paris and Milan• Enumerate the helpful diagnostic clues in the differential diagnoses of thyroid conditions• Discuss pitfalls and differential diagnosis of melanoma cytology• To understand the importance of a Quality Assurance (QA) and Quality Control (QC)
in a cytopathology laboratory• Recognize benign/reactive entities that could potentially mimic malignant lung tumors• Understand the application of cytology for molecular diagnosis and its
indication in lung cancer
2018 Cyto-econference Chair
Michael J. Thrall, MDCytopathology Fellowship Director
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aprIl, 23, 2019
Aspiration Cytology of Neck Cysts in Adults: Morphologic Features and Ancillary Testing Strategies
Christopher C. Griffith, MD, PhD Assistant Professor of Pathology Emory University Atlanta, Georgia
Fine needle aspiration is a common initial diagnostic test for adults presenting with a cystic lesion of the neck . One of the main challenges for a cytopathologist in this situation is the recognition of cystic metastatic squamous cell carcinoma, which has become increasingly important due to the rising incidence of HPV positive oropharyngeal squamous cell carcinoma . This presentation will review cytomorphologic features of common cystic neck lesions in adults and review helpful ancillary testing strategies .
May 28, 2019
Kidney FNA – Clues and Pitfalls
Eva M. Wojcik, MDDepartment Chair, Pathology Loyola UniversityMaywood, Illinois
Fine-needle aspiration (FNA) biopsy of the kidney has a non disputable role in the diagnosis and treatment of renal lesions . Particularly, recent improvements in renal imaging techniques have brought renal FNA to the forefront, since small and asymptomatic renal masses are increasingly being detected . Consequentially, there is a pressing need for accurate typing as well as grading of RCC which, in turn, will aid in selection of cases of nephron sparing surgeries, partial nephrectomies or even non-surgical measures
like cryoablation . These therapeutic options are however not advisable for high-grade neoplasms . During this webinar we will review broad spectrum of renal FNAs including normal renal structures, inflammatory and reactive changes, cystic lesions and benign and malignant neoplasms . We will emphasize diagnostic clues and pitfalls .
junE 25, 2019
Challenges and Pitfalls in Cytomorphology of Melanoma
Xiaoqi Lin, MD, PhD Associate Professor Northwestern University Chicago, Illinois
Melanoma is a highly aggressive malignant tumor arising from skin, eye, and internal organs . Melanoma frequently metastasizes to lung, liver, the central nervous system, and other diverse sites . Metastasis may be the first clinical presentation in some patients . Melanoma can present with various cytologic patterns including plasmacytoid, undifferentiated, epithelioid, spindle-shaped/sarcomatoid, or macrophage-like . The cytoplasm can be delicate, granular, or vacuolated . These cytologic features can potentially mimic carcinoma, plasmacytoma/lymphoma, sarcoma, macrophages, or granular cell tumor, among others . Melanin pigment may be present in some cases, with differentials that include lipofuscin pigments, hemosiderin, or anthracotic pigment . Diagnostically challenging cases with clinical findings, Diff-Quik and/or Papanicolaou stained FNA smears and touch preps, H&E stained cell blocks/cores, and ancillary studies will be presented .
july 23, 2019
Common Diagnostic Pitfalls in Thyroid Cytopathology
Adebowale J. Adeniran, MDAssociate Professor; Director of Cytopathology Yale University School of Medicine New Haven, Connecticut
This presentation provides a comprehensive review of the most frequently encountered diagnostic pitfalls in both neoplastic and non-neoplastic thyroid conditions . Specific diagnostic scenarios and/or pitfalls that help in the differential diagnosis are discussed as well as the judicious use of ancillary studies when necessary . The presentation is delivered with ample illustrations of microscopic features to tackle common and uncommon diagnostic challenge in everyday routine practice of thyroid cytopathology .
auGust 27, 2019
Role of Cytology and Immunochemistry in Diagnosis of Metastatic Malignancies in the Lung: A Critical Appraisal
Varsha Manucha, MDAssociate ProfessorUniversity of Mississippi Medical CenterJackson, Mississippi
Israh Akhtar, MDProfessorUniversity of Mississippi Medical CenterJackson, Mississippi
Lung is one of the most common sites for primary and metastatic malignancies and a challenging site to diagnose primary versus a metastatic origin of the tumor on cytology . Pathologic diagnosis of the site of origin of cancer has major implications in the management and staging purposes and may have to be followed by testing for predictive/ prognostic markers . The clinical history of a known extrapulmonary primary or the radiologic findings of multiple nodules in the lung is useful in arriving at the right diagnosis, but is not always available . Rarely pulmonary metastasis may be the first manifestation of an extrapulmonary tumor or may even present as a single nodule . The use of immunochemistry facilitates the diagnosis but could be misleading .
These 60-minute webinars begin at 3:00 pm Eastern Time on the fourth Tuesday of each month (with the exception of December, which is the second Tuesday).
Earn 2 CME/CMLE – 2 SaM CrEditS pEr WEbinar
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sEptEMbEr 24, 2019
Pulmonary Cytology: Is it Benign or Malignant? Diagnostically Challenging Cases and Mimickers
Maria Luisa C. Policarpio-Nicolas, MDStaff PathologistCleveland ClinicCleveland, Ohio
This is a case-based didactic session that presents a spectrum of pulmonary/mediastinal specimens . Participants will be presented a variety of cases with diagnoses ranging from benign, reactive process to malignant . The differential diagnosis on the common and uncommon entities, ancillary tests and important pointers to avoid pitfalls will be discussed . An algorithm that will serve as a guide in navigating respiratory specimens including diagnostic pitfalls will also be presented .
oCtobEr 22, 2019
Lung and Mediastinal Cytology
Anjali Saqi, MD, MBAProfessor of Pathology, Cell BiologyColumbia University Medical CenterNew York, New York
Andre I. Moreira, MD, PhDProfessor of PathologyNew York University Langone HealthNew York, New York
Small biopsy and cytology specimens are often the only available specimen for diagnosis and determination of prognostic and predictive markers in lung cancer .Despite several diagnostic categories available for resected specimen, cytological diagnosis is restricted to adenocarcinoma, squamous cell carcinoma and neuroendocrine tumors . Diagnostic criteria and use of ancillary tests for tumor classification will be discussed . Tumors of the mediastinum are rare and the site can be involved in many different tumors . Most pathologists are not familiar with mediastinal disease, specially cytological features of these entities . In this webnair we will discuss a cytologic diagnostic approach for mediastinal diseases .
novEMbEr 26, 2019
Let’s Make the QA and QC More Meaningful and Effective for Your Lab
Ghazal Khan, MBA, MS, CT(ASCP)Chief CytotechnologistUniversity of Chicago MedicineChicago, Illinois
In this brief talk to educate participants about the importance of quality assurance (QA) and quality control (QC) in a cytopathology laboratory, I will address why it is important to have a QA plan and what measures should be part of the QA plan . In addition, the webinar will address how to implement QA measures and how to track them as well as who should participate in a QA plan and their role .
dECEMbEr 10, 2019
Glandular and Rare Lesions in GYN Cytopathology
Donna K. Russell, MEd, CT(ASCP)HT Education Coordinator; Cytopathology Residency/Fellowship TrainingUniversity of Rochester Medical Center Naples, New York
This case based session explores a variety of squamous, glandular and rare lesions in gynecologic cytopathology, as well as their differentials . There will be emphasis on key features of challenging cases in both squamous and glandular lesions . The session will provide an overview of benign, reactive and neoplastic lesions in liquid based preparations (SurePath and Thin Prep) . Pitfalls and differential diagnoses will be highlighted through a number of case presentations of common and uncommon findings in GYN cytopathology . Appropriate use of ancillary studies and morphologic criteria will also be discussed .
january 28, 2020
Interobserver Reproducibility for The Standardized Terminology Systems: Bethesda-GYN, Paris and Milan
Daniel F.I. Kurtycz, MDMedical Director University of WisconsinMadison, Wisconsin
In this session, we will discuss the reasons for and some of the outcomes of the current diagnostic terminology systems . These structures were created by professional consortiums because of direct needs in diagnostic cytopathology, and in hopes of improving diagnostic consistency between institutions and observers . The methods used to create the systems and the associated reproducibility studies will be discussed . Unanswered questions and aspirations of the systems will be considered .
FEbruary 25, 2020
Fine Needle Aspiration Cytology of Solid and Cystic Pancreatic Lesions: A Review
Momin T. Siddiqui, MDDirector of CytopathologyWeill-Cornell MedicineNew York, New York
The presentation will encompass slide review and extensive pictorial revies of solid and cystic pancreatic lesions . Morphologic features needed for diagnosing these lesions will be discussed . Review of cell blocks as well as ancillary testing currently used for some of these diagnostic entitites will also be addressed .
MarCh, 24, 2020
A Practical Approach to Cervical Cytology with Correlations to ASCCP Management Guidelines
Eric C. Huang, MD, PhDAssociate ProfessorDirector of Cytopathology and Fellowship ProgramUniversity of WashingtonSeattle, Washington
This webinar will help pathologists and cytotechnologists understand the downstream effect of the cytologic diagnoses that we make daily in Pap smears . This session focuses on the diagnostic criteria according to the Bethesda System for Reporting Cervical Cytology and associated diagnostic pitfalls for each cervical abnormality . In addition, the attendees will learn how to approach Pap smears based on the clinical management for the various cervical abnormalities .
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American Society of Cytopathology100 West 10th Street, Suite 605Wilmington, DE 19801
Continuing Medical Education (CME)The American Society of Cytopathology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians .The American Society of Cytopathology designates this live and enduring educational activity for a maximum of 24 AMA PRA Category 1 Credits™ . Physicians should only claim credit commensurate with the extent of their participation in the activity .American Board of Pathology Maintenance of Certification (MOC)This product can help fulfill the CME requirements and Self-Assessment Modules (SAMs) mandated by the American Board of Pathology Continuing Certification process .Continuing Medical Laboratory Education (CMLE)The ASC designates these activities for the indicated number of Continuing Medical Laboratory Education (CMLE) credit hours . This program is approved for 24 continuing education credits in the State of Florida and 12 in the State of California .The credit on each webinar is good for three years from the live presentation date .
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Earn 2 CME/CMLE – 2 SaM CrEditS pEr WEbinar
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