1st Joint Meeting of the International Society for Autonomic Neuroscience and the American Autonomic Society

ISAN/AAS 2011

Búzios, Rio de Janeiro, Brazil September 12-16, 2011

Scientific Program

MONDAY, SEPTEMBER 12, 2011 10:00-20:00 Registration

ISAN/AAS WORKSHOP Clinical Assessment of the Autonomic Nervous System

Which Tests For What Problems?

13:00-13:05 Welcome and Introduction Mark W. Chapleau, USA

13:05-13:20 Autonomic Systems: Pathways, Effectors & Pathophysiologic Correlates David S. Goldstein, USA

Assessment of the Autonomic Nervous System in Autonomic Disorders

Chairs: Antonio C. Nobrega, Brazil and Nicola Montano, Italy 13:20-13:40 Orthostatic Hypotension, Intolerance & Syncope

Benjamin Levine, USA 13:40-13:50 Discussion 13:50-14:10 Hypertension, Heart Failure & Other Cardiovascular Disorders

Murray Esler, Australia 14:10-14:20 Discussion 14:20-14:40 Autonomic Neuropathies

Roy Freeman, USA 14:40-14:50 Discussion 14:50-15:10 Synucleinopathies – Neurodegenerative Diseases

David S. Goldstein, USA 15:10-15:20 Discussion 15:20-15:35 COFFEE BREAK 15:35-15:50 Gastrointestinal Disorders

Thomas Chelimsky, USA 15:50-15:55 Discussion 15:55-16:10 Urogenital Disorders

To be Announced 16:10-16:15 Discussion

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16:15-16:35 Genetics and Other Emerging Methods David Robertson, USA

16:35-16:45 Discussion 16:45-17:00 Open Discussion and Adjourn

Chair: Felicia Axelrod 18:30-19:00 WELCOME TO ISAN/AAS 2011

Sérgio Cravo, Chair of the Local Organizing Committee Mark W. Chapleau and Julian F.R. Paton, Co-Chairs of the Program Committee Jean-Pierre Timmermans, President of ISAN Mickael J. Joyner, President of AAS

19:00-20:00 OPENING PLENARY LECTURE

Purinergic Neurotransmission: Pathophysiology and Therapeutic Potential Geoffrey Burnstock, University College Medical School, London, UK

20:00 WELCOME COCKTAIL TUESDAY, SEPTEMBER 13, 2011 8:00-10:00 Symposia 1 and 2 Symposium 1: Afferent Baroreflex Dysfunction: From Molecules to Man Chairs: Horacio Kaufmann, USA and Mark W. Chapleau, USA 8:00-8:25 Introduction: afferent vs. efferent baroreflex dysfunction and failure

Horacio Kaufmann, USA 8:25-8:50 Heritable and environmental factors influencing baroreflex control of blood

pressure in humans Jens Jordan, Germany

8:50-9:15 Molecular determinants of afferent baroreflex function, insights from mouse models Mark W. Chapleau, USA

9:15-9:40 Familial dysautonomia: a genetic disease with afferent baroreflex failure Lucy Norcliffe-Kaufmann, USA

9:40-9:55 Preserved cardiovascular reflex regulation in patients with continuous flow left ventricular assist device Jens Tank, D Malehsa, K Heusser, K Hegemann, A Diedrich, C Bara, J Jordan, M Strueber. Hannover, Germany and Nashville, TN, USA

9:55-10:00 General Discussion 10:00-10:15 COFFEE BREAK Symposium 2: Bladder to Brain; Autonomic Basis of Urinary Dysfunction Chairs: Marcus Drake, UK and Tony Pickering, UK 8:00-8:05 Introduction

Marcus Drake, UK

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8:05-8:30 Higher CNS centres in lower urinary tract dysfunction Clare Fowler, UK

8:30-8:55 Peripheral pathophysiology in lower urinary tract dysfunction Christopher Fry, UK

8:55-9:20 Spinal cord and brainstem control of the micturition cycle Marcus Drake, UK

9:20-9:30 Micturition suppressing sites in the periaqueductal grey of the rat. Ella Stone, JH Coote, TA Lovick. Birmingham, UK

9:30-9:40 Pre-treatment with purinergic antagonists alter the functional response to methacholine in the inflamed rat urinary bladder. Patrick Aronsson, R Vesela, M Andersson, G Tobin. Gothenburg, Sweden

9:40-9:50 Role of the urothelium in afferent sensitivity to potassium in the mouse bladder Laura-Joy Gooch, DM Daly, CR Chapple, D Grundy. Sheffield, UK

9:50-10:00 Summary and General Discussion 10:00-10:15 COFFEE BREAK 10:15-11:00 PLENARY LECTURE 2

The Spectrum of Baroreflex Failure David Robertson, Vanderbilt University, Nashville, TN, USA

11:00-13:00 Poster Session I 13:00-14:00 Lunch & Trade Display (Exhibits) 14:00-16:00 Symposia 3 and 4 Symposium 3: Functional Imaging of the Brainstem and Cortical Sites of Autonomic Control in Human Subjects Chair: Vaughan Macefield, Australia 14:00-14:25 Does the cortical autonomic network “listen” or “speak” during cardiovascular

arousal? Kevin Shoemaker, Canada

14:25-14:50 Neural correlates of the autonomically mediated integration of emotion and bodily state Marcus Gray, UK

14:50-15:15 Identification of sites of sympathetic outflow during concurrent recordings of sympathetic nerve activity and fMRI Luke Henderson, Australia

15:15-15:40 Structural and functional brain alterations in sleep disordered breathing Ron Harper, USA

15:40-15:55 Importance of the medial amygdala to the neurogenic hypertension in Schlager mice Kristy Jackson, TP Nguyen-Huu, K Palma-Rigo, PJ Davern, GA Head. Melbourne, Australia

15:55-16:00 General Discussion

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16:00-16:15 COFFEE BREAK Symposium 4: Neural Disorders of the Gastrointestinal Tract: Mechanisms and Prospects for Treatment Chairs: Patricia Castelucci, Brazil and David Linden, USA 14:00-14:05 Introduction and welcome

Patricia Castelucci, Brazil 14:05-14:35 A common neuropathological mechanism of action for postoperative-, sepsis- and

trauma-induced ileus Tony Bauer, USA

14:35-15:05 The physiology and pathophysiology of hydrogen sulfide in the gastrointestinal tract David Linden, USA

15:05-15:25 Disordered colorectal function after spinal cord injury, animal studies point to novel treatments John B. Furness, Australia

15:25-15:30 Introduction to student presentations David Linden, USA

15:30-15:40 Amplification of cholinergic neurotransmission by adenosine released from Interstitial Cells of Cajal at a tripartite myenteric synapse of the rat ileum Isabel Silva, P Marques, C Vieira, F Ferreirinha, T Magalhães-Cardoso, M Duarte-Araújo, P Correia-de-Sá.

15:40-15:50 The role of NO in intestinal ischemia/reperfusion injury to enteric neurons in mice Leni Rivera, M Thacker, L Pontell, HJ Cho, JB Furness. Melbourne, Australia

15:50-16:00 Effect of obesity on P2X2 receptors and chemical coding in myenteric neurons of male and female (ob/ob) mice Marcia Mizuno, LA Velloso, P Castelucci. Sao Paulo, Brazil

16:00-16:15 COFFEE BREAK 16:15-18:15 Debate: What is Important to Know about Modulation of Sympathetic

Transmission Chair: Ian (JC) McGrath, UK

16:15-16:25 Synergy between sympathetic neurotransmitters: molecular, cellular or imaginary? Ian (JC) McGrath, UK

16:25-16:40 Neurovascular transmission during natural patterns of nerve activity James A. Brock, Australia

16:40-16:50 Questions/Debating Points from Floor 16:50-17:05 Disruption of vascular neuroeffector transmission in hypertension

James J. Galligan, USA 17:05-17:15 Questions/Debating Points from Floor 17:15-17:30 Factors influencing the role of ATP as a vascular sympathetic neurotransmitter

William Dunn, UK 17:30-17:40 Questions/Debating Points from Floor

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17:40-17:55 Using rat sympathetic neurons as a model system for post-synaptic receptor function Paul Kammermeier, USA

17:55-18:15 Questions/Debating Points and General Discussion 18:15-19:15 AAS Business Meeting WEDNESDAY, SEPTEMBER 14, 2011 8:00-10:00 Symposia 5 and 6 Symposium 5: Neuro-Glial-Vascular Mechanisms in the CNS Control of Autonomic Function Chairs: Javier E. Stern, USA and Julian F.R. Paton, UK 8:00-8:25 Role of astrocytes as brain sensors of cardiovascular hemodynamics

Jessica A. Filosa, USA 8:25-8:50 Modulation of brain neurovascular plasticity by afferent signaling: effects of

exercise Lisete Michelini, Brazil

8:50-9:15 Cerebral perfusion: a major determinant of arterial pressure Julian F.R. Paton, UK

9:15-9:40 Neuro-glial-vascular signaling mechanisms influencing neurohumoral integration in the brain Javier E. Stern, USA

9:40-9:55 Autoimplantation of astrocytes into cardiovascular center of brainstem causes sympathoinhibition and decreases the mortality rate in hypertensive rats Takuya Kishi, K Sunagawa. Kyushu, Japan

9:55-10:00 General Discussion 10:00-10:15 COFFEE BREAK Symposium 6: Autonomic Dysfunction in Obesity: Consequences and Mechanisms Chair: Kamal Rahmouni, USA 8:00-8:30 Autonomic dysfunction in obesity: Clinical implications

Murray Esler, Australia 8:30-9:00 Fetal programming of autonomic function: Effects of maternal obesity

Paul D. Taylor, UK 9:00-9:30 Sympathetic nerve activation in obesity: Mechanistic insights

Kamal Rahmouni, USA 9:30-9:45 Hyperphagia and obesity in mice with genetic ablation of gastrointestinal brain-

derived neurotrophic factor Edward A Fox, JE Biddinger, KR Jones, J McAdams, A Worman. Boulder, CO USA

9:45-10:00 Hypertension in obesity-prone Sprague-Dawley rats is associated with blunted renal sympathoinhibitory and regional vasodilator responses to gastric peptides Daniela M Sartor, JMY How, T Pumpa. Melbourne, Australia

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10:00-10:15 COFFEE BREAK 10:15-11:00 PLENARY LECTURE 3

The Autonomic Nervous System in Body Protection and Pain Wilfrid Janig, Physiologisches Institut Christian-Albrechts-Universität Kiel, Germany

11:00-13:00 Poster Session II 13:00-14:00 Lunch & Trade Display (Exhibits) 14:00-16:00 Symposia 7 and 8 Symposium 7: Pathophysiology of Obstructive Sleep Apnea: From Animal Models to Consequences to Human Health Chairs: Mark W. Chapleau, USA and Sérgio L. Cravo, Brazil 14:00-14:30 Molecular mechanisms of chemoreceptor activation and sustained

sympathoexcitation in disease Mark W. Chapleau, USA

14:30-15:00 Cardiovascular responses to obstructive sleep apnea: are chemoreceptors as important as we think? Sérgio L. Cravo, Brazil

15:00-15:30 Sleep apnea, arrhythmias and sudden death Virend Somers, USA

15:30-15:45 Neurobehavioral and autonomic dysfunction in obstructive sleep apnea Juan Idiaquez, R Del Rio, R Iturriaga, J Santin, I Santos. Chile

15:45-16:00 Electrophysiological properties of expiratory and pre-sympathetic neurons in the ventrolateral of rats submitted to chronic intermittent hypoxia Davi José de Almeida Moraes, DB Zoccal, BH Machado. Ribeirao Preto, Brazil

16:00-16:15 COFFEE BREAK Symposium 8: Autonomic Neuro-Immunomodulation: The Interplay between Two Integrative Systems – Nervous and Immune Systems Chair: Valdo José Dias da Silva, Brazil 14:00-14:25 Signaling the brain in systemic inflammation: The role of perivascular cells

Paul E. Sawchenko, USA 14:25-14:50 Stress-dependent hypertension and the role of T lymphocytes

Paul Marvar, USA 14:50-15:15 Neuroendocrine control of T cell development in mammals

Wilson Savino, Brazil 15:15-15:40 Neuro-immunomodulation in Chagasic cardiomyopathy

Marcus Paulo R. Machado, USA 15:40-15:55 Identifying rat sympathetic neurons that regulate immune function

Bradford Bratton, D Martelli, MJ McKinley, D Trevaks, RM McAllen. Melbourne, Australia

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15:55-16:00 General Discussion 16:00-16:15 COFFEE BREAK 16:15-18:15 Symposia 9 and 10 Symposium 9: Autonomic Control of Body Temperature Chair: Shaun Morrison, USA 16:15-16:40 TRP channels in thermoregulation

Andrej Romanovsky, USA 16:40-17:05 Stress-induced hyperthermia

Kazuhiro Nakamura, Japan 17:05-17:30 The preoptic hypothalamus and thermoregulation

Robin McAllen, Australia 17:30-17:55 Brainstem pathways contributing to thermoregulation

Shaun Morrison, USA 17:55-18:10 Leptin amplifies the action of thyrotropin releasing hormone in the nucleus of the

solitary tract: implications for thermogenesis Grelinda E. Hermann, RC Rogers. Baton Rouge, LA

18:10-18:15 General Discussion 18:15-18:30 COFFEE BREAK Symposium 10: Glia-Neuron Interactions in Autonomic Neuroscience Chair: Benedito H. Machado, Brazil 16:15-16:40 Astroglial control of the respiratory and autonomic activities

Alexander Gourine, UK 16:40-17:05 Glial cells and glutamate synapses in the paraventricular nucleus of the

hypothalamus Jaideep Bains, Canada

17:05-17:30 The role of glia in the purinergic modulation of the preBötzinger complex inspiratory rhythm generating network Gregory Funk, Canada

17:30-17:55 Glial–neural interactions in brainstem autonomic control Richard C. Rogers, USA

17:55-18:15 General Discussion 18:15-18:30 COFFEE BREAK Hot Topic Platform Presentations by Trainees/Junior Scientists – I 18:30-18:45 Neurochemically coding functional subpopulations of rat sympathetic

preganglionic neurons activated after glucoprivation Lindsay Parker, NN Kumar, AK Goodchild. Sydney, Australia

18:45-19:00 P2X7 receptor-dependent intestinal afferent hypersensitivity in a mouse model of post-infectious irritable bowel syndrome Christopher Keating, P Pelegrin, CM Martinez, D Grundy. Sheffield, UK

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19:00-19:15 Transient changes in BDNF parallel plasticity observed in the IML following distal axon injury Aminata Coulibaly, BF Walsh, LG Isaacson. Oxford, OH, USA

19:15-19:30 Aging is associated with reduced white matter connectivity and fractional anisotropy in cortical autonomic regions Ruma Goswami, KN Norton, MF Frances, HA Sharma, JK Shoemaker. Ontario, Canada

19:30 CONGRESS DINNER THURSDAY, SEPTEMBER 15, 2011 8:00-10:00 Symposia 11 and 12 Symposium 11: The Battle between Brain Disease and Heart Health Chair: William T. Talman, USA 8:00-8:25 Stress and the human heart

Murray Esler, Australia 8:25-8:50 Psychological depression and heart disease

Angela Grippo, USA 8:50-9:15 Subarachnoid hemorrhage and the heart

Jonathon Zaroff, USA 9:15-9:40 Selective lesions in the Nucleus Tractus Solitarii and sudden death in rats

William T. Talman, USA 9:40-9:55 Analysis and treatment of cardiac alterations in an animal model of anxio-

depressive pathologies Caroline Sévoz-Couche, F Camus, ML Bourhis, C Becker, JJ Benoliel. Paris, France

9:55-10:00 General Discussion 10:00-10:15 COFFEE BREAK Symposium 12: The Osmopressor Response – A Newly Discovered Pathway for Cardiovascular Regulation Chairs: Satish R. Raj, USA and Jens Jordan, Germany 8:00-8:05 Introduction by Chairs 8:05-8:30 Water: A surprising treatment for orthostatic hypotension

Jens Jordan, Germany 8:30-8:55 Water: A new treatment for blood phobia syncope

Chih Cherng Lu, Taiwan 8:55-9:20 The osmopressor response – What have we learned from the mouse?

Julia McHugh, USA 9:20-9:45 Molecular and cellular afferent transduction mechanisms of the osmopressor

response Gary Lewin, Germany

9:45-10:00 General Discussion

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10:00-10:15 COFFEE BREAK 10:15-11:00 PLENARY LECTURE 4

Neural Mechanisms of Chronic Pain: Lessons from Translational Studies of Endometriosis Karen J. Berkley, Florida State University, USA

11:00-13:00 Poster Session III 13:00-14:00 Lunch & Trade Display (Exhibits) 14:00-16:00 Symposia 13 and 14 Symposium 13: Drug and Exercise Therapy for Postural Orthostatic Tachycardia Syndrome (POTS) Chairs: Michael J. Joyner, USA and David Robertson, USA 14:00-14:25 From syndrome to genes and back – controversies and future directions

Emily M. Garland, USA 14:25-14:50 Drug therapy for POTS, past present and future?

Satish R. Raj, USA 14:50-15:15 Lessons from exercise physiology and spaceflight for POTS

Benjamin Levine, USA 15:15-15:40 The Dallas exercise intervention for POTS

Qi Fu, USA 15:40-15:55 Postural orthostatic tachycardia syndrome, chromatin regulation and the

noradrenaline transporter gene Richard Bayles, Melbourne, Australia

15:55-16:00 General Discussion 16:00-16:15 COFFEE BREAK Symposium 14: Autonomic Control and Its Relationship with Biological Cycles Chairs: Daniel Vianna, Australia and Rodrigo Cunha Alvim de Menezes, Brazil 14:00-14:30 Endogenous circadian control of autonomic, cardiovascular and metabolic function

Frank A.J.L. Scheer, USA 14:30-15:00 Ultradian rhythmicity in autonomic and behavioural parameters

Bill Blessing, Australia and Youchirou Ootsuka, Japan 15:00-15:30 Ultradian rhythms of mammalian energy metabolism and their relationship to food

availability and ambient temperature Carola Meyer and Gerhardt Heldmaier, Germany

15:30-16:00 Autonomic control during different sleep stages Matteo Cerri, Italy

16:00-16:15 COFFEE BREAK Hot Topic Platform Presentations by Trainees/Junior Scientists – II

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16:15-16:30 Orexin activates brown adipose tissue (BAT) thermogenesis in the rat Tudor Domenico, CJ Madden, SF Morrison. Portland, OR, USA

16:30-16:45 Sympathetic over activity occurs before the hypertension in the two-kidney one clip model Elizabeth Oliveira-Sales, AP Abdala, E Colombari, RR Campos, JFR Paton. Sao Paulo, Brazil and Bristol, UK

16:45-17:00 Acute, specific transgenic ‘silencing’ of Phox2b-expressing neurons in the caudal nucleus tractus solitarius reduces arterial pressure and respiration at rest and in response to hypercapnia in conscious rats Aihua Li, APL Abdala, JFR Paton, Nattie EE. Bristol, UK and Dartmouth, USA

17:00-17:15 Angiotensin type 1A receptors transfected into the A1 neurons inhibit baroreflex gain and the cardiovascular response to stress in AT1A

–/– mice Kesia Palma-Rigo, TP Nguyen-Huu, PJ Davern, JK Bassi, JL Elghozi, AM Allen, Head GA. Melbourne, Australia and Paris, France

17:15-17:30 Sympathetic activation after myocardial infarction in the rat: role of the arterial baroreflex, cardiac afferent reflexes and sex Carolyn Barrett, MI Pinkham. Auckland, New Zealand

17:30-17:45 Balancing resting arterial pressure and sympathetic nerve activity: influence aging in women Emma Hart, N Charkoudian, BG Wallin, TB Curry, MJ Joyner. Rochester, MN, USA

17:45-18:00 The norepinephrine paradox in hereditary sensory and autonomic neuropathy type IV Lucy Norcliffe-Kaufmann, FB Axelrod, H Kaufmann. New York City, USA

18:00-19:00 ISAN Business Meeting FRIDAY, SEPTEMBER 16, 2011 8:00-10:00 Symposia 15 and 16 Symposium 15: The Cardiac Vagal Axis – Recent Developments Chairs: Jack Cheng, USA and Robin McAllen, Australia 8:00-8:25 Structural and functional plasticity in the cardiac vagal axis

Jack Cheng, USA 8:25-8:50 Processing of physiological signals by cardiac ganglion cells

Tony Pickering, UK 8:50-9:15 What the vagal nerve stimulation can do for the diseased heart?

Kenji Sunagawa, Japan 9:15-9:40 Modulation and rescue of vagal neuroeffector transmission

David Paterson, UK 9:40-9:55 Reduced heart rate variability in the diabetic heart is reversed by inhibition of

glycogen synthase kinase 3β activity Charles M. Welzig, Y Zhang, H-J Park, K Picard, JB Galper. Charleston, SC and Boston, MA

9:55-10:00 General Discussion

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10:00-10:15 COFFEE BREAK Symposium 16: Oxidative Stress and Autonomic Function Chairs: Valdir A. Braga, Brazil and Eduardo Colombari, Brazil 8:00-8:25 The brain ACE2/Ang-(1-7)Mas receptor axis and oxidative stress

Eric Lazartigues, USA 8:25-8:50 Dissecting oxidative stress signaling pathways in forebrain cardiovascular circuits

using viral vectors for gene transfer Robin L. Davisson, USA

8:50-9:15 Oxidant signaling in the hindbrain modulates salt appetite in hypertension Steve Mifflin, USA

9:15-9:40 Sympathetic vasomotor control by oxidative stress in renovascular hypertension Ruy R. Campos, Brazil

9:40-9:55 SFO-targeted (pro)renin receptor deletion attenuates hypertension is associated with reduced oxidative stress in human renin-angiotensinogen transgenic mice. W Li, H Peng, SJ McDaniels, CD Sigmund, Yumei Feng. New Orleans, Louisiana, and Iowa City, IA, USA

9:55-10:00 General Discussion 10:00-10:15 COFFEE BREAK 10:15-11:00 PLENARY LECTURE 5

Biomarkers, Mechanisms, and Treatment of Autonomic Failure in Parkinson Disease and Related Disorders David S. Goldstein, Clinical Neurology Section NINDS, NIH, Bethesda, MD, USA

11:00-13:00 Poster Session IV 13:00-14:00 Lunch & Trade Display (Exhibits) 14:00-16:00 Symposia 17 and 18 Symposium 17: Role of the Vagus Nerve in Pain and Inflammation Chair: David Grundy, UK 14:00-14:30 Vagal nutrient signaling and immunoprotection

Wim A. Buurman, The Netherlands 14:30-15:00 Vagally-mediated intestinal immune response

Wouter de Jonge, The Netherlands 15:00-15:30 Determinants and modulators of vagal nociceptors

Marian Kollarik, USA 15:30-15:45 Vagal afferents: nociception and antinociception

David Grundy, UK 15:45-16:00 Evidence for neuroepithelial bodies (NEBs) as vagal mechanotransducers in the

intrapulmonary mouse airway epithelium Robrecht Lembrechts, I Brouns, K Schnorbusch, I Pintelon, JP Timmermans, D Adriaensen. Antwerp, Belgium

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16:00-16:15 COFFEE BREAK Symposium 18: Cardiac Sympathetic Neuroplasticity: Implications for Health and Disease Chairs: Peter G. Smith, USA and Beth Habecker, USA 14:00-14:25 Sympathetic neurotransmission in the cardiac system: Functional plasticity and

regulation by target-derived factors Susan Birren, USA

14:25-14:50 Neurotrophins and cytokines induce remodeling of cardiac sympathetic nerves after ischemia-reperfusion Beth Habecker, USA

14:50-15:15 Cholinergic transdifferentiation of cardiac sympathetic nerves in heart failure Keiichi Fukuda, Japan

15:15-15:40 Changes in cardiac sympathetic innervation in response to pharmacotherapy Peter G. Smith, USA

15:40-15:55 Cardiac sympathetic denervation in symptomatic and asymptomatic carriers of the E46K mutation in the synuclein gene Beatriz Tigero Merino, JC Gomez-Esteban, H Kaufmann, V Llorens, JJ Zarranz. Cruces Hospital, Spain and New York City, USA

15:55-16:00 General Discussion 16:00-16:15 COFFEE BREAK 16:15-17:00 CLOSING PLENARY LECTURE

Baroreceptors and the Cardiovascular Autonomic Control: 50 Years from Basic Research to Clinical Application Eduardo M. Krieger, Heart Institute (InCor), University of São Paulo, Brazil

17:00 CLOSING CEREMONY AND ANNOUNCEMENT OF ELSEVIER AWARDS

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POSTER SESSION I Tuesday, September 13, 2011 11:00-13:00 Baroreceptor Reflexes Poster 1 Methionine sulfoxide reductase-A is required for normal baroreflex

sensitivity and sympathovagal balance: evidence for redox regulation of autonomic function in young mice Sabharwal R1, Abboud FM1, Chapleau MW2 - 1University of Iowa - Iowa City, Iowa, USA; 2University of Iowa & Veterans Affairs Medical Center - Iowa City, Iowa, USA

Poster 2 Differential Sympathetic activation and baroreceptor reflex sensitivity induced by hepatic cirrhosis in rats. Estrela HFG1, Bergamaschi CT1, Campos RR1 - 1Federal University of São Paulo - Department of Physiology

Poster 3 Bursts of muscle sympathetic nerve activity are absent in familial dysautonomia Macefield V.G.1, Norcliffe-Kaufmann LJ2, Axelrod FB3, Kaufmann H4 - 1University of Western Sydney - School of Medicine ; 2New York University School of Medicine - Physiology & Neuroscience; 3NYU School of Medicine - Pediatrics and Neurology; 4NYU medical center - Neurology

Poster 4 Preserved cardiovascular reflex regulation in patients with continuous flow left ventricular assist device Tank J1, Malehsa D2, Heusser K1, Hegemann K1, Diedrich A3, Bara C2, Jordan J4, Strueber M2 - 1Hannover Medical School, Hannover, Germany - Institute of Clinical Pharmacology; 2Hannover Medical School, Hannover, Germany - Department of Cardiac, Thoracic, Transplantation, and Vascular Surgery; 3Vanderbilt University School of Medicine, Nashville, TN, USA - Department of Medicine, Division of Clinical Pharmacology, Autonomic Dysfunction Service; 4Medical School Hannover - Clinical Pharmacology

Poster 5 Effects of positive airway pressure on heart rate variability and baroreflex sensitivity in healthy subjects. Gonçalves TR1, Barros RBM1, Nunes MVL2, Farinatti PTV3, Giannella Neto A2, Soares PP1 - 1Fluminense Federal University - Laboratory Experimental and Applied Exercise Physiology; 2Rio de Janeiro Federal University - Biomedical Engineering Program; 3Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil. - Graduate Program in Physical Activity Sciences of the Salgado de Oliveira University, Rio de Janeiro, Brazil

Poster 6 Baroreflex changes only stressed volume not the slope of the venous return surface in anesthetized dogs Sakamoto T1, Sunagawa K1 - 1Kyushu University - cardiovascular medicine

Poster 7 Baroreflex sensitivity and blood pressure transients in postmenopausal women Barnes JN1, Charkoudian N2, Hart EC1, Joyner, Michael1 - 1Mayo Clinic - Anesthesiology; 2Mayo Clinic - Physiology and Biomedical Engineering

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Poster 8 Effect of combined administration of testosterone and cocaine on baroreflex activity in unanesthetized rats. Engi SA1, Cruz FC2, Leão RM3, Corrêa FMA4, Planeta CS2, Crestani CC1 - 1School of Pharmaceutical Sciences of Araraquara, São Paulo State University- UNESP - Department of Natural Active Principles and Toxicology; 2Faculdade de Ciências Farmacêuticas - UNESP/Araraquara - Depto. Princípios Ativos Naturais e Toxicologia; 3Faculdade de Ciências Farmacêuticas - UNESP - Araraquara - Depto. Princípios Ativos Naturais e Toxicologia; 4Universidade de Sâo Paulo - Farmacologia

Poster 9 Baroreflex mechanisms regulating the occurrence of sympathetic action potentials in human muscle sympathetic nerve activity Salmanpour A1, Shoemaker JK2 - 1the University of Western Ontario - ; 2the University of Western Ontario - the School of Kinesiology

Poster 10 Low intensity resistance training increases spontaneous baroreflex sensitivity Oliveira LR1, Macedo FN1, Santana MNS1, Oliveira KMS1, Melo VU1, BARRETO AS1, Santos MRV2, Santana-Filho VJ1 - 1Universidade Federal de Sergipe - Fisiologia; 2UFS - Departamento de Fisiologia / CCBS

Poster 11 Blunted increases in leg vascular conductance to carotid baroreflex activation in young women Vianna LC1, Kim A1, Fairfax ST1, Fadel PJ1 - 1University of Missouri - Department of Medical Pharmacology and Physiology

Poster 12 Clinical implications dysfunction of cardiopulmonary baroreflex in patients with coronary artery disease Mamontov OV, Shlyakhto EV2, Konradi AO1 - 1Almazov Federal Heart, Blood and Endocrinology Centre - Research Laboratory of the pathogenesis and treatment of hypertension ; 2Almazov Federal Heart, Blood and Endocrinology Centre - director

Poster 13 BAROREFLEX SENSITIVITY IN PATIENTS WITH RESISTANT HYPERTENSION: SPIRONOLACTONE EFFECTS Konrady A1, A Bagrov2, Shlyakhto E1, Emelyanov I1 - 1Almazov Federal Heart, Blood and Endocrinology Center, Saint-Petersburg, Russian Federation - Arterial Hypertension Department; 2National Institute on Aging, NIH, Baltimore, USA2 - Hypertension Unit

Poster 14 Analysis of heart rate response to maximal expiratory pressure and Valsalva maneuver in healthy young men Minatel V1, Karsten M1, Neves LMT1, Pissinato IG1, Beltrame T1, Borghi-Silva A1, Catai AM1 - 1Federal University of Sao Carlos - Physiotherapy Department

Autonomic Basis of Urinary Function & Dysfunction Poster 15 Micturition suppressing sites in the periaqueductal grey of the rat Stone

E1, Coote JH1, Lovick TA1 - 1University of Birmingham - School of Clinical and Experimental Medicine

Poster 16 Pre-treatment with purinergic antagonists alter the functional response to methacholine in the inflamed rat urinary bladder Aronsson P1, Vesela R2, Andersson M1, Tobin G1 - 1University of Gothenburg - Pharmacology; 2Charles University - Pharmacy

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Poster 17 Autonomic receptor-mediated influence on the proliferation of the human bladder urothelial UROtsa and T24 cell lines Andersson M1, Aronsson P1, Giglio D1, Tobin G1 - 1University of Gothenburg - Pharmacology

Poster 18 Role of the urothelium in afferent sensitivity to potassium in the mouse bladder. Gooch LJ1, Daly DM1, Chapple CR2, Grundy D1 - 1University of Sheffield - Biomedical Science; 2Royal Hallamshire Hospital - Urology

Poster 19 Design and feasibility of ICEPAC (Interstitial Cystitis Elucidation of Psychophysiologic and Autonomic Characteristics) –. Autonomic and somatic measures Chelimsky G1, Janata J2, Ialacci S3, Louttit M3, Daneshgari F4, Chelimsky TC3 - 1Case Medical Center and Case Western Reserve University - Pediatrics; 2Case Medical Center and Case Western Reserve University - Psychiatry; 3Case Western Reserve University - Neurology; 4Case Medical Center and Case Western Reserve University - Urology

Poster 20 Design and Feasibility of ICEPAC (Interstitial Cystitis: Elucidation of Psychophysiologic and Autonomic Characteristics) – Stress Response and Psychophysiologic Measures Janata JW1, Daneshgari F2, Buffington CAT3, Chelimsky G4, Pajer K5, Louttit M6, Zhang D6, Chelimsky TC6 - 1Case Western Reserve University School of Medicine - Psychiatry; 2Case Medical Center and Case Western Reserve University - Urology; 3Ohio State University - School of Veterinary Science; 4University Hospitals of Cleveland - Pediatrics; 5Ohio State University - Pediatrics; 6Case Western Reserve University - Neurology

Poster 21 Intravesical pressure (IP) alterations evoked by carbachol into the fourth brain ventricle (4th V) in female rats Cafarchio, E.M.1, Almeida RL1, Ogihara CA1, Saviolli, I.H.1, Colombari E2, Sato MA1 - 1Faculdade de Medicina do ABC - Morfologia e Fisiologia; 2UNESP - Fisiologia e Patologia

Poster 22 “Design and Feasibility of ICEPAC (Interstitial Cystitis Elucidation of Psychophysiologic and Autonomic Characteristics) – Bupivacaine instillation and Urodynamic Measures “ Veizi IE1, Daneshgari F2, Hijaz A1, Louttit M3, Ialacci S3, Janata J4, Chelimsky G5, Chelimsky TC3 - 1University Hospitals Case Medical Center - Urology; 2Case Medical Center and Case Western Reserve University - Urology; 3Case Western Reserve University - Neurology; 4University Hospitals Case Medical Center - Psychiatry; 5Case Medical Center and Case Western Reserve University - Pediatrics

Poster 23 Bladder overactivity due to global impairment of ecto-NTPDases in humans with lower urinary tract disorders exhibiting unbalanced ATP / adenosine formation Silva I1, Correia J1, Ferreirinha F1, Magalhães-Cardoso T1, Silva-Ramos M2, Sévigny3, Correia-de-Sá P1 - 1ICBAS - University of Porto, Portugal - Lab Pharmacology and Neurobiology / UMIB; 2Centro Hospitalar do Porto, Portugal - Serviço de Urologia; 3Univ. Laval, Québec, QC, Canada - Centre de Recherche en Rhumatologie et Immunologie, CHU and Départ. Microbiologie-Infectiologie et d’Immunologie, Fac. Médecine

CNS Sites of Autonomic Control & Responses to Stress, Arousal and Fear

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Poster 24 The hippocampal connection to the autonomic network Norton KN1, Shoemaker JK2 - 1The University of Western Ontario - School of Kinesiology; 2The University of Western Ontario - Kinesiology

Poster 25 Aging is associated with reduced white matter connectivity and fractional anisotropy in cortical autonomic regions Goswami R1, Norton KN1, Frances MF1, Sharma HA2, Shoemaker JK1 - 1The University of Western Ontario - School of Kinesiology; 2The University of Western Ontario - Robarts Research Institute

Poster 26 Identifying a central command network of sympathetic control in the awake human James C, Henderson LA2, Macefield V.G.1 - 1University of Western Sydney - School of Medicine ; 2University of Sydney - Department of Anatomy & Histology

Poster 27 The interface between heart and brain: a case of aborted sudden death in autonomic epilepsy OSORIO J1, Reis CHM2, Bello YB3, Martins Jr GC2, Figueiredo JM4, CASTRO RRT4 - 1Hospital Geral de Nova Iguaçu - Residência em Clínica Médica; 2Hospital Geral de Nova Iguaçu - Serviço de Neurologia; 3Hospital Geral de Nova Iguaçu - Residência em Neurologia; 4Hospital Geral de Nova Iguaçu - Unidade Semi-intensiva

Poster 28 Sympathetic Nerve Activity during Deep Brain Stimulation. Sverrisdottir YB1, Basnayake1, Green AL1, Paterson DJ1 - 1University of Oxford - Department of Physiology, Anatomy & Genetics

Poster 29 Brain frontal cortical activation is related to cardiac vagal activity in the depressive elderly: a pilot study Oliveira NA1, Deslandes A2, Silveira H3, C.G. Araújo4, Laks J5 - 1Laboratório de Neurociêcia do exercício-UGF - Laboratório de Neuropsiquiatria geriátria- UFRJ; 2Laboratório de Neurociência do exercício-UGF - Escola Nacional de Saúde Pública-Fundação Oswaldo Cruz, Rio de Janeiro; 3Laboratório de Neurociência do exercício-UGF - Laboratório de Neuropsiquiatria Geriátrica-UFRJ; 4UGF - CLINIMEX; 5Centro de Alzheimer e Outros Transtornos Mentais na Velhice-CDA/IPUB-UFRJ - Laboratório de Neuropsiquiatria Geriátrica-UFRJ

Poster 30 Dynamic changes of stress-index under simulated psychoemotional strain depending on vegetative state and self-appraisal level of examinees Stepanyan AYu1, Grigoryan VH1 - 1Yerevan State University - Human&Animal Physiology

Poster 31 Analysis and treatment of cardiac alterations in an animal model of anxio-depressive pathologies Sévoz-Couche C1, Camus F1, Bourhis ML1, Becker C1, Benoliel JJ1 - 1UPMC/INSERM UMRS 975, Department of Pain and Stress, 91 boulevard de l'Hôpital - 75013, Paris, France

Poster 32 Angiotensin type 1A receptors transfected into the A1 neurons inhibit baroreflex gain and the cardiovascular response to stress in AT1A

-/- mice Palma-Rigo K1, Nguyen-Huu TP2, Davern PJ2, Bassi JK3, Elghozi JL1, Allen AM3, Head GA2 - 1Paris – Centre de Recherche Cardiovasculaire - INSERM U 970; 2Baker IDI Heart and Diabetes Research Institute - Neuropharmacology Laboratory; 3University of Melbourne - Department of Physiology

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Poster 33

Importance of the medial amygdala to the neurogenic hypertension in Schlager mice Jackson K L1, Nguyen-Huu T P2, Palma-Rigo K2, Davern PJ2, Head GA2 - 1Baker IDI Heart and Diabetes Research Institute & Monash University - Neuropharmacology Laboratory; 2Baker IDI Heart and Diabetes Research Institute - Neuropharmacology Laboratory

Poster 34

The expression of contextual fear conditioning involves dorsal hippocampus nitric oxide/ cGMP pathway. FABRI DRS1, Hott, S. C.1, D.G. Reis1, Corrêa FMA2 - 1UNIVERSIDADE DE SÃO PAULO - FARMACOLOGIA; 2Universidade de Sâo Paulo - Farmacologia

Poster 35

Disinhibition of the medial prefrontal cortex reveals functionally distinct regions that influence diverse autonomic outflows in the rattus norvegicus Hassan SF1, Burke PG1, Cornish JL2, Goodchild AK1 - 1Macquarie University - Australian School of Advanced Medicine; 2Macquarie University - Department of Pyschology

Poster 36

Deactivation of posterior insula does not modify cardiovascular variables in conscious rats Del Rio R1, Contreras M1, Moya EA1, Iturriaga R1 - 1Lab Neurobiology - P. Universidad Catolica de Chile

Poster 37

Bed nucleus of the stria terminalis β1, but not β2-adrenoceptors, are involved with expression of contextual fear conditioning of rats Hott, S. C.1, FABRI DRS1, Gomes FV2, Reis DG3, Corrêa FMA4, Resstel LBM2 - 1Universidade de São Paulo - farmacologia; 2FMRP-USP - Farmacologia; 3Faculdade de Medicina de Ribeirão Preto, USP - Farmacologia; 4Universidade de Sâo Paulo - Farmacologia

Poster 38

Medial prefrontal cortex endocannabinoid system modulates the baroreflex activity through CB1 receptors. Ferreira-Junior NC1, FEDOCE AG1, Alves FHF1, Correa FMA1, Resstel LBM1 - 1Faculdade de Medicina de Ribeirão Preto-USP - Farmacologia

Poster 39

The dorsomedial hypothalamus (DMH) plays a strain-dependent role in vascular responses to cocaine but not cold stress in conscious rats Knuepfer MM1, Bušauskas M1 - 1St. Louis University School of Medicine - Pharmacol. & Physiol. Science

Poster 40

Autonomic markers of emotional processing: skin sympathetic nerve activity during exposure to emotionally-charged images in humans Brown R, James C, Henderson LA2, Macefield V.G.1 - 1University of Western Sydney - School of Medicine ; 2University of Sydney - Department of Anatomy & Histology

Poster 41

Respiratory pattern reflects state and trait anxiety in rats. Carnevali L1, Sgoifo A1, Trombini M1, Landgraf R2, Neumann ID3, Nalivaiko E4 - 1University of Parma - Parma, Italy; 2Max Planck Institute for Psychiatry - Munich, Germany; 33University of Regensburg - Regensburg, Germany; 4University of Newcastle - Newcastle, Australia

Poster 42

Alpha2 but not alpha1 and beta adrenoceptors in the lateral septal area modulates cardiovascular responses evoked by restraint stress in rats. Scopinho, A.A.1, Reis DG1, Resstel LBM1, Corrêa FMA1 - 1Faculdade de Medicina de Ribeirão Preto, USP - Farmacologia

Poster 43

Contribution of excitatory amino acid receptors in the dorsomedial hypothalamus and periaqueductal gray to the asymmetry and lateralization

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Poster 44 in the cardiovascular responses to stress in rats Xavier CH1, Vaz G.C.1, Lima A.M.1, Ianzer D.2, Nalivaiko E3, Fontes MAP1 - 1Universidade Federal de Minas Gerais - Fisiologia e Biofísica; 2Instituto Butantan - Centro de Toxinologia Aplicada; 3University of Newcastle - School of BIomedical Sciences and Pahrmacy

Poster 45 Ultradian 90-min biological rhythm is attenuated in orexin-deficient mice Ootsuka Y1, Miyata K1, Kuwaki T1 - 1Kagoshima University - Graduate school of Medical & Dental Science, Department of Physiology

Neural Disorders of the GI Tract Poster 46 Characterization of GI tract’s autonomic innervation in a mouse model of

Familial Amyloid Polyneuropathy Teixeira D1, Saraiva MJ1 - 1Institute for Molecular and Cell Biology - Molecular Neurobiology

Poster 47 Investigation of the effectiveness of a ghrelin receptor agonist to stimulate the defecation centre in spinal cord injured rats Furness JB1 - 1University of Melbourne - Anatomy and Cell Biology

Poster 48 The role of NO in intestinal ischemia/reperfusion injury in mice Rivera LR1, Thacker M1, Pontell L1, Cho HJ1, Furness JB1 - 1University of Melbourne - Anatomy and Cell Biology

Poster 49 Developmental regional distribution and neurochemical coding of enteric neurons in the zebrafish mutant lessen compared to the wildtype zebrafish. uyttebroek l1, Shepherd I2, Hubens G1, Timmermans JP3, Van Nassauw L1 - 1Laboratory of Human Anatomy and Embryology - University of Antwerp; 2Department of Biology - Emory University, Atlanta; 3Laboratory of Histology & Cell Biology - University of Antwerp

Poster 50 Assessment quercetin supplementation in diabetic Wistar rats: analysis of vasoactive intestinal polypeptide (VIP) immunoreactive myenteric neurons from jejunum Martins JVCP1, Souza SRG2, I. Zignani3, Melo CGS4, Miranda Neto MH3, Zanoni JN3 - 1Universidade Estadual de Maringá - Departamento de Ciências Morfológicas (DCM); 2Universidade Estadual de Maringá - Departamento de Ciências Morfológicas; 3Universidade Estadual de Maringá - Ciencias Morfológicas; 4Faculdade de Odontologia de Bauru. Universidade de São Paulo - Anatomia

Poster 51 Ileum of diabetic rats (Rattus norvegicus): effect of supplementation with 2% L-glutamine on glial cells and myenteric neurons ZANONI JN1, TRONCHINI EA1, TASHIMA CM1, ALVES EPB1, PEREIRA RVF1 - 1Universidade Estadual de Maringá - Departamento de Ciências Morfológicas

Poster 52 Effects of age and prolonged caloric restriction on plasmatic constituent, oxidative state and the cholinergic and nitrergic myenteric neurons of the proximal colon of Wistar rats (Rattus norvegicus) Schoffen JPF1, Santi-Rampazzo AP2, Cirilo CP2, Zapater MCVU2, Vicentini FA2, Sá-Nakanishi AB3, Comar JF3, Natali MRM2 - 1Universidade Estadual do Norte do Paraná - Centro de Ciências Biológicas; 2Universidade Estadual de Maringá - Departamento de Ciências Morfológicas; 3Universidade Estadual de Maringá - Departamento de Bioquímica

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Poster 53 aging rats under ascorbic acid supplementation: study of immunoreactive myenteric neurons of proximal colon to cgrp neurotransmitter Defani MA1, Zanoni JN2, Mata JZ3 - 1Universidade Estadual de Maringá - Departamento de Ciências Morfológicas; 2Universidade Estadual de Maringa - Ciencias Morfologicas; 3UEM - Departamento de Ciências Morfológicas

Poster 54 Effects of experimental ulcerative colitis on the P2X7 receptor of the enteric neurons of rat distal colon. Da Silva Marcos Vinicius1, Marosti ARB2, Castelucci P3 - 1Universidade de São Paulo - Instituto de Ciêmcias Biomédicas; 2Universidade de São Paulo - Departamento de Anatomia - ICBIII; 3USP - Departamento de Anatomia

Poster 55

P2X7 receptor-dependent intestinal afferent hypersensitivity in a mouse model of post-infectious irritable bowel syndrome. Keating CD1, Pelegrin P2, Martinez CM2, Grundy D1 - 1University of Sheffield - Biomedical Science; 2University Hospital “Virgen de la Arrixaca”-FFIS - Inflammation and Experimental Surgery Unit

Poster 56 Distinct phenotypes of the neural crest- and placode-derived nociceptors innervating the guinea pig esophagus. Ru F1, Surdenikova L2, Brozmanova M2, Banovcin P jr3, KOLLARIK M1 - 1The Johns Hopkins School of Medicine, Baltimore - Medicine; 2Jessenius Medical School, Martin, Slovakia - Pathophysiology; 3Jessenius Medical School, Martin, Slovakia - Gastroenterology

Poster 57 Study of the P2X2 receptor in neurons and enteric glial cells of the ileum rats subjected to ischemia / reperfusion Mendes CE1, Palombit K2, Tavares de Lima W3, Castelucci P4 - 1Instituto de Ciências Biomédicas/USP - Departamento de Anatomia; 2Universidade de São Paulo - Anatomia; 3ICB - USP - Farmacologia; 4USP - Departamento de Anatomia

Poster 58 effect of obesity on p2x2 receptor and chemical coding in myenteric neurons of males and females mice (ob/ob). Mizuno MS1, Velloso LA2, Castelucci P1 - 1USP - Departamento de Anatomia; 2Universidade Estadual de Campinas - Clínica Médica

Poster 59 The umami taste receptor ligand, monosodium glutamate, induces the peristaltic reflex in rat colon by activation of T1R1/T1R3 taste receptors. Grider JR1, Bala V.1, Mahavadi S.1, Murthy K.S.1, Lyall V.J.1 - 1Virginia Commonwealth University - School of Medicine

Poster 60 NEUROPROTECTIVE effect of the aqueous extract of Agaricus blazei Murill on HuC/D immunoreactive myenteric population of the jejunum of Wistar rats (Rattus norvergicus) in aging process. Santi-Rampazzo AP1, Cirilo CP1, Schoffen JPF2, Zapater MCVU1, Vicentini FA1, Soares AA3, Peralta RM3, Natali MRM1 - 1Universidade Estadual de Maringá - Departamento de Ciências Morfológicas; 2Universidade Estadual do Norte do Paraná - Centro de Ciências Biológicas; 3Universidade Estadual de Maringá - Departamento de Bioquímica

Poster 61 Effects of intestinal ischemia and reperfusion on P2X7 receptor expressing neurons of the rat ileum enteric nervous system Palombit K1, Mendes CE2, Tavares de Lima W3, Castelucci P4 - 1Instituto de Ciências Biomédicas - Universidade de São Paulo - Anatomia; 2Instituto de Ciências Biomédicas/USP - Departamento de Anatomia; 3ICB - USP - Farmacologia; 4USP - Departamento de Anatomia

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Poster 62 Experimental Colitis Induced by Trinitrobenzenesulfonic Acid (TNBS) in Wistar Rats: Effects in the Colon Morphology and Intrinsic Innervations Natali MRM1, Gonçalves, CCM2, Souza Silva, JF3, Hernandes, L.3, Bersani-Amado CA4 - 1Universidade Estadual de Maringá - Departamento de Ciências Morfológicas; 2Universidade Estadual de Maringá - Enfermagem; 3Universidade Estadual de Maringá - Ciências Morfológicas; 4UEM - Farmácia e Farmacologia

Poster 63 Study of intestinal ischemia/reperfusion on p2x2 receptor and chemical code of rat ileum enteric nervous system Marosti ARB1, Da Silva Marcos Vinicius2, Castelucci P3 - 1Universidade de São Paulo - Departamento de Anatomia - ICBIII; 2Universidade de São Paulo - Departamento de Anatomia - ICBIII; 3USP - Departamento de Anatomia

Poster 64 Amplification of cholinergic neurotransmission by adenosine released from Interstitial Cells of Cajal at a tripartite myenteric synapse of the rat ileum Silva I1, Marques P1, Vieira C1, Ferreirinha F1, Magalhães-Cardoso T1, Duarte-Araújo M1, Correia-de-Sá P1 - 1ICBAS - Universidade do Porto - Laboratório de Farmacologia e Neurobiologia - UMIB

Poster 65 Immunohistochemical analysis of Interstitial Cells of Cajal in diabetic Wistar rats supplemented with quercetin. FREZ, FCV1, Souza SRG1, Perego, LM1, Moreira, EA1, ZANONI JN1 - 1Universidade Estadual de Maringá - Departamento de Ciências Farmacêuticas

Poster 66 Study of the P2X7 receptor and chemical coding on the submucosal plexus of the ileum rats subjected to ischemia/reperfusion Castelucci P1, Meloni I2, Jurjuck JI3, Mendes CE4, Tavares de Lima W5, Palombit K6 - 1Universidade de São Paulo - Departamento de Anatomia; 2USP - disfunções metábolicas; 3FMU - estudante; 4Instituto de Ciências Biomédicas/USP - Departamento de Anatomia; 5ICB - USP - Farmacologia; 6Universidade de São Paulo - Anatomia

Poster 67 Upregulated alpha2-adrenergic receptors in the muscularis externa of the ileum following hapten-induced colitis contribute to normalization of small intestinal motility in the guinea pig. Linden DR1, Peck RD1, Stoltz GJ1 - 1Mayo Clinic - Physiology and Biomedical Engineering

Poster 68 Colitis-induced brain-derived neurotrophic factor in rat dorsal root ganglia mediates calcitonin gene-related peptide expression and bladder hyperactivity Qiao LY1, Yu SJ1, Gulick MA1 - 1Virginia Commonwealth University - Department of Physiology and Biophysics

Poster 69 Therapeutic approaches for familial amyloid neuropathies affecting the peripheral and autonomic nervous system Saraiva MJ1 - 1Institute for molecular and cell biology - Molecular Neurobiology

Poster 70 Cholecystokinin [CCK] amplifies the gastric accommodation reflex in the rat: in vivo recordings from the dorsal motor nucleus of the vagus. Viard E1, Rogers RC1, Hermann GE1 - 1Pennington Biomedical Research Center - Autonomic Neuroscience

Poster 71 Hyper-dopaminergic vomiting crises in familial dysautonomia Norcliffe-Kaufmann LJ1, Axelrod FB2, Kaufmann H3 - 1New York University School of Medicine - Physiology & Neuroscience; 2NYU School of Medicine - Pediatrics and Neurology; 3New York University School of Medicine - Neurology

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Poster 72 Effects of fumonisin on myoenteric neurons NADPH – positive diaphorasis of the large intestine (proximal colon) in Wistar rats (Rattus novergicus) Amorim SSS1, Sousa FC2, Schamber CR2, Natali MRM3, Miranda-Neto MH2, Mello EVLS2 - 1Universidade Estadual de Maringa - Departamento de Ciências Morfologicas; 2Universidade Estadual de Maringa - Ciencias Morfologicas; 3Universidade Estadual de Maringá - Departamento de Ciências Morfológicas

POSTER SESSION II Wednesday, September 14, 2011 11:00-13:00 Sympathetic Neurotransmission & End-Organ Responses Poster 73 Dissecting the adenosine triphosphate docking site in P2X4 receptor from

the copper allosteric coordination complex. Huidobro-Toro JP1, Navarrete C1, Lagos C2, Loeb B3, Bull P4 - 1Laboratorio de Nucleótidos, Departamento de Fisiología and CARE - P. Universidad Católica de Chile, Santiago, CHILE; 2Centro de Bio-Informática UC (CBUC), Facultad de Ciencias Biológicas - P. Universidad Católica de Chile, Santiago, CHILE; 3Departamento de Química Inorgánica, Facultad de - P. Universidad Católica de Chile, Santiago, CHILE; 4Departamento Genética Molecular y Microbiología - P. Universidad Católica de Chile, Santiago, CHILE

Poster 74 Optical techniques for monitoring norepinephrine, and vesicular monoamine, transporter rates in sympathetic nerve terminals of mouse vas deferens Brain KL1 - 1University of Birmingham - Clinical and Experimental Medicine

Poster 75 Real time monitoring of neurotransmitter uptake and storage in PC-12 cells: implication for co-storage and co-transmission Sidaway P1, Brain KL1 - 1University of Birmingham - Clinical and Experimental Medicine

Poster 76 An increased contribution of L-type Ca2+ channels to activation of vascular muscle underlies spinal cord injury-induced augmentation of neurovascular transmission in rat tail artery Al Dera HS1, Habgood MD2, Furness JB1, Brock JA1 - 1University of Melbourne - Anatomy and Cell Biology; 2University of Melbourne - Pharmacology

Poster 77 Neurochemically coding functional subpopulations of rat sympathetic preganglionic neurons activated after glucoprivation Parker LM1, Kumar NN1, Goodchild AK1 - 1Macquarie University - Australian School of Advanced Medicine

Poster 78 Preganglionic input drives upregulation of adrenomedullin/adrenomedullin2 in murine principal sympathetic neurons Wessels L1, Pfeil U1, Faulhammer P1, Kummer W1 - 1Justus-Liebig-University Giessen - Institute of Anatomy and Cell Biology

Poster 79 How electrode damage distorts phase plane trajectories of spikes driven by strong and weak nicotinic synapses in rat sympathetic neurons Horn JP1, Springer MG1 - 1University of Pittsburgh School of Medicine - Department of Neurobiology

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Poster 80 Development of calbindin-containing neurons in sympathetic ganglia of rats and cats Maslyukov PM1, Emanuilov A.I.2, Konovalov V.V.1, Nozdrachev A.D.3 - 1Yaroslavl State Medical Academy - Normal Physiology; 2Yaroslavl State Medical Academy - Human Anatomy; 3Pavlov Institute of Physiology - Laboratory of physiology of reception

Poster 81 Characterizing the functional role of phosphoinositides and cholesterol in sympathetic co-transmission at the rat vas deferens neuroeffector junction Donoso MV1, Miranda R1, Huidobro Toro P1 - 1Laboratorio de Nucleótidos, Departamento de Fisiología and CARE. - P. Universidad Católica de Chile, Santiago, CHILE

Poster 82 Accelerated Intraneuronal Catecholamine Loss Related to Decreased Vesicular Uptake in Lewy Body Diseases Goldstein D1, Holmes C1, Kopin IJ1, Sharabi Y1 - 1Clinical Neurocardiology Section, CNP, DIR, NINDS, NIH, Bethesda, MD 20892-1620 USA - -

Poster 83 Sympathetic innervation interacts with myocyte-derived factors to regulate neonatal rat cardiomyocyte maturation Kreipke RE1, Birren SJ2 - 1Brandeis University - Neuroscience; 2Brandeis University - Biology

Poster 84 Sex differences in sympathetic neurovascular transduction in humans Tan CO1, Tzeng YC2, Taylor JA1 - 1Harvard Medical School - Physical Medicine and Rehabilitation; 2University of Otaga - Surgery and Anesthesia

Poster 85 Human sympathetic neurovascular transduction during isocapnic hypoxia Tzeng YC1, Tan CO2, Hamner JW3, Taylor JA2 - 1University of Otaga - Surgery and Anesthesia; 2Harvard Medical School - Physical Medicine and Rehabilitation; 3Harvard Medical School - Physical Medicine & Rehabilitation

Poster 86 Functional responses to renal and cardiac denervation in sheep with sepsis Calzavacca P1, Ramchandra R1, Bellomo R2, May CN1 - 1Florey Neuroscience Institute, University of Melbourne, Victoria, Australia - Systems Neurophysiology; 2Austin Hospital, Melbourne, Victoria, Australia - Department of Intensive Care

Poster 87 Reproducibility of sympathetic response to cold face test: comparison with three other pressor stimuli Khurana RK1, Chriss E1 - 1Union Memorial Hospital - Medicine

Poster 88 Sympathetic Activation during the Cold Pressor Test changes Cerebral Compliance Falvo MJ1, Blatt M2, Jasien JJ1, Deegan BM3, OLaighin G3, Serrador JM4 - 1VA NJ Health Care System - War Related Illness & Injury Study Center; 2Department of Veterans Affairs - War Related Illness and Injury Study Center; 3National University of Ireland Galway - Electrical & Electronic Engineering; 4War Related Illness & Injury Study Center, VA NJ Health Care System - Harvard Medical School, Boston, MA

Poster 89 Reactive oxygen species and products of cyclooxygenase modulate the contractile response to phenylephrine in aorta from normotensive and renal hypertensive 2K-1C rats Silva BR1, Bendhack LM2 - 1FMRP-USP - Farmacologia; 2USP - FCFRP

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Poster 90 CELLULAR MECHANISMS INVOLVED IN THE VASODILATATION INDUCED BY NATRIURETIC PEPTIDES ANP AND CNP IN RAT ISOLATED AORTA. Andrade FA1, Bendhack LM2 - 1Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo - Farmacologia; 2Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo - Física e Química

Neuro-Glial-Vascular Interactions Poster 91 Autoimplantation of Astrocytes into Cardiovascular Center of Brainstem

Causes Sympathoinhibition and Decreases the Mortality Rate in Hypertensive Rats Kishi T1, Sunagawa K2 - 1Kyushu University Graduate School of Medical Sciences - Advanced Therapeutics for Cardiovascular Diseases; 2Kyushu University - Cardiovascular Medicine

Poster 92 Cerebral blood may contribute to the set-point of arterial pressure in the rat Paton JFR1, Malpas SC2, Barrett CJ3 - 1University of Bristol - Physiology & Pharmacology; 2University of Auckland - Physiology; 3The University of Auckland - Department of Physiology

Poster 93 An anti-hypertensive role for the GPR182 orphan receptor in the rostral ventrolateral medulla of hypertensive rats? Milosavljevic S1, Japundzic-Zigon N2, Paton JFR3, Murphy D4 - 1University of Bristol - Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology; 2University of Belgrade - Institue of Pharmacology, Clinical Pharmacology and Toxicology, School of Medicine; 3University of Bristol - Physiology & Pharmacology; 4University of Bristol - Henry Wellcome L.I.N.E

Poster 94 Astrocytes in rat nucleus of the solitary tract are activated by low glucose or glucoprivic challenges McDougal DH1, Rogers RC1, Hermann GE2 - 1Pennington Biomedical Research Center - Laboratory of Autonomic Neuroscience; 2Pennington Biomedical Research Center - Autonomic Neuroscience

Poster 95 DO GLIAL CELLS IN THE NTS PLAY A ROLE IN AUTONOMIC AND RESPIRATORY CONTROL IN RATS? Costa KM1, Moaes DJA1, Machado BH1 - 1School of Medicine of Ribeirão Preto, University of São Paulo - Department of Physiology

Poster 96 Selective glial, like selective neuronal, damage in the nucleus tractus solitarii disturbs cardiac and cardiovascular function Talman WT1, Nitschke Dragon D1, Jones S1, Moore SA2, Lin L-H1 - 1Univ. of Iowa and VAMC - Neurology; 2Univ. of Iowa and VAMC - Pathology

Poster 97 Purinergic modulation of preBötzinger Complex inspiratory rhythm generating networks Zwicker JD1, Pagliardini S1, Kasparov S2, Gourine AV3, Funk GD1 - 1University of Alberta - Physiology; 2University Of Bristol, UK - Physiology; 3University College London -

Poster 98 Astroglial control of the respiratory and autonomic activities Gourine AV1, Kasparov S2 - 1University College London - Neuroscience, Physiology and Pharmacology; 2University of Bristol - Physiology and Pharmacology

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Autonomic Dysfunction in Obesity & Hypertension Poster 99 Hyperphagia and obesity in mice with genetic ablation of gastrointestinal

brain-derived neurotrophic factor Fox EA1, Biddinger JE1, Jones KR2, McAdams J1, Worman A1 - 1Purdue University - Psychological Sciences; 2University of Colorado, Boulder - Molecular, Cellular & Developmental Biology

Poster 100 Hypertension in obesity-prone Sprague-Dawley rats is associated with blunted renal sympathoinhibitory and regional vasodilator responses to gastric peptides Sartor DM1, How JMY1, Pumpa T1 - 1University of Melbourne - Medicine

Poster 101 Prevalence and treatment of depression are differentially associated with insulin resistance and obesity. Gilbey MP1, Casale C2, Lei S2, Malik SN2, Marina N1, Cotena E1, Heath DI3, Sufi P3, Gray R3, Mohamed-Ali V2 - 1University College London - Neuroscience, Physiology and Pharmacology; 2University College London - Medicine; 3Whittington Hospital - North London Obesity Surgery Service (NLOSS)

Poster 102 Regulation of sympathetic nerve activity by AMPA and NMDA receptors in the rostral ventrolateral medulla of obese Zucker rats. Huber DA1, Schreihofer AM1 - 1University of North Texas Health Science Center - Department of Integrative Physiology

Poster 103 Changes in arterial baroreceptor reflex control of renal sympathetic nerve activity in high fat diet-induced obesity as a predictor of hypertension in Wistar rats Fardin NM1, Oyama LM2, Campos RR1 - 1UNIFESP - Fisiologia Cardiovascular e Respiratória; 2UNIFESP - Ciências da Saúde

Poster 104 Obstructive sleep apnea and chronic stress exacerbate sympathetic activation and baroreflex dysfunction in patients with metabolic syndrome Toschi-Dias E1, Trombetta IC1, Maki-Nunes C1, Drager LF2, Angelo LF1, Alves MJNN1, Cepêda-Fonseca FX1, Lorenzi Filho, G2, Negrão CE3, Rondon MUPB3 - 1Heart Institute (InCor), University of São Paulo Medical School - Unit of Cardiovascular Rehabilitation and Exercise Physiology; 2Heart Institute (InCor), University of São Paulo Medical School - Sleep Laboratory - Pulmonary Division; 3Heart Institute (InCor), University of São Paulo Medical School and School of Physical Education and Sport, University of São Paulo - Unit of Cardiovascular Rehabilitation and Exercise Physiology and Department of Biodynamic of the Human Body Movement

Poster 105 Involvement of the dorsomedial hypothalamus in the physiological responses evoked by air jet stress in wistar rats fed a high fat diet Abreu ARR1, De Abreu ARR1, Santos LGBT1, De Menezes RC1 - 1Universidade Federal de Ouro Preto - Departamento de Ciências Biológicas

Poster 106 GLUTAMATERGIC NEUROTRANSMISSION IN RVLM OF MSG OBESE CONSCIOUS RATS CUNHA NV1, Martins-Pinge MC2 - 1Universidade Estadual de Londrina - UEL - Depto de Ciências Fisiológicas; 2Universidade Estadual de Londrina - Ciências Fisiológicas

Poster 107 Relationships among autonomic dysfunction, obstructive sleep apnea, and insulin resistance in childhood obesity Oliveira FMS1, Tran WH1, Bhatia R2, Lesser DJ2, Chalacheva P1, Mittelman SD3, Keens TG4, Ward SLD4, Khoo MCK1 - 1University of Southern California - Biomedical Engineering; 2Children's Hospital Los Angeles - Division of Pediatric Pulmonology; 3Children's Hospital Los Angeles, Center

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for Endocrinology, Diabetes, and Metabolism - University of Southern California, Biomedical Engineering; 4Children's Hospital Los Angeles, Division of Pediatric Pulmonology - University of Southern California, Biomedical Engineering

Poster 108 GABA and Glutamate in the Paraventricular Nucleus During the Onset of Renal Wrap Rat Hypertension Parsell DM, Laimon-Thomson E, Northcott CA1 - 1Michigan State University - Pharmacology and Toxicology

Poster 109 Sympathetic over activity occurs before the hypertension in the two-kidney one clip model Oliveira-Sales EB1, Abdala A.P.2, Colombari E3, Campos RR1, Paton JFR4 - 1Universidade Federal de São Paulo - Fisiologia; 2University of Bristol - Physiology; 3UNESP - Fisiologia e Patologia; 4University of Bristol - Physiology & Pharmacology

Poster 110 Brain eicosanoids contribute to increased sympathetic activity and blood pressure in angiotensin II-salt hypertension in rats Fink GD1, Jeyaraj NA1 - 1Michigan State University - Pharmacology and Toxicology

Poster 111 Differential role of central insulin action and the autonomic nervous system on the hepatic production of glucose (HPG) in Wistar and SHR Ribeiro IMR1, Antunes VR2 - 1USP - Fisiologia e Biofísica; 2Universidade de São Paulo - Fisiologia

Poster 112 Mesenchymal stem cells decrease AT1 receptor in the RVLM and the hypertension in 2K-1C Wistar rats . Oliveira-Sales EB1, Maquigussa E2, Semedo P2, Guilhermino LP2, Câmara NOS2, C.T. Bergamaschi1, Boim M2, Campos RR1 - 1Universidade Federal de São Paulo - Physiology; 2Universidade Federal de São Paulo - Nephrology Department

Poster 113 Acute superoxide scavenging restores depressed baroreflex sensitivity in spontaneously hypertensive rats DD Guimarães1, NM Oliveira-Monteiro1, Braga VA1 - 1Universidade Federal da Paraíba - Ciências Veterinárias

Poster 114 SFO-targeted (pro)renin receptor deletion attenuates hypertension is associated with reduced oxidative stress in human renin-angiotensinogen transgenic mice. Li W1, Peng H1, McDaniels SJ1, Sigmund CD2, Feng Y1 - 1Tulane University - Physiology; 2University of Iowa - Department of Pharmacology, Center on Functional Genomics of Hypertension

Poster 115 Silencing either NOX2 or NOX4 in the paraventricular nucleus attenuates aldosterone/NaCl-induced hypertension in mice XUE B1, Beltz TG1, Guo F1, Hay M2, Johnson AK3 - 1The University of Iowa - Psychology; 2University of Arizona - Physiology; 3The University of Iowa - Depts. of Psychology, Health and Human Physiology, Pharmacology and the Cardiovascular Center

Poster 116 Changes in angiotensin II receptors (AT1 and AT2) protein expression within the sympathetic premotor neurons in response to renal denervation in renovascular hypertensive rats Nishi EE1, Bergamaschi CT1, Perry JC2, Campos RR1 - 1Unifesp - Fisiologia; 2Unifesp - Psicobiologia

Poster 117 Molecular orchestration of neuronal adaptation underlying central setpoint of blood pressure in the rat Vadigepalli R1, Paton JFR2, Gonye G2, Schwaber JS2 - 1Thomas Jefferson University - Pathology Anatomy Cell Biology ; 2University Of Bristol, UK - Physiology

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Pathophysiology of Obstructive Sleep Apnea Poster 118 Hypoxia and hyperoxia affect cardiovascular responses to obstructive apnea

after carotid chemoreceptor inactivation in rats Angheben JMM1, Silva TA1, Rossi MV1, Cravo SLD1, Schoorlemmer GHM1 - 1UNIFESP - Physiology

Poster 119 Exposure to chronic intermittent hypoxia alters sympathetic reflexes and neurotransmission in the rostral ventrolateral medulla (RVLM) in Sprague-Dawley rats Silva AQ1, Schreihofer AM1 - 1University of North Texas Health Science Center - Integrative Physiology

Poster 120 Depressed TS-evoked glutamatergic transmission on NTS neurons of rats submitted to intermittent hypoxia is due to reduced number of functional synapses Almado CE1, Machado BH1, Leão RX1 - 1School of Medicine of Ribeirao Preto - University of Sao Paulo - Department of Physiology

Poster 121 Synaptic properties of peripheral chemoreflex second-order neurons in the NTS of rats Accorsi-Mendonça D1, Castania JA2, Bonagamba LGH3, Machado BH4, Leão RX5 - 1FMRP-USP - Physiology; 2FMRP - Fisiologia; 3FMRP - USP - FISIOLOGIA; 4Faculdade de Medicina de Ribeirão Preto-USP - Fisiologia; 5Faculdade de Medicina de Ribeirão Preto, USP - Fisiologia

Poster 122 Cardiovascular responses to obstructive apnea are reduced during REM sleep in rats Schoorlemmer GHM1, Rossi MV2, Cravo SL3 - 1UNIFESP-EPM - Physiology; 2Universidade Federal de São Paulo - Fisiologia; 3Unifesp/EPM - Fisiologia Cardiovascular

Poster 123 The role of respiratory effort and peripheral chemoreceptors in cardiovascular responses induced by obstructive apnea in rats Ferreira CB1, Schoorlemmer GHM1, Cravo SL1 - 1Universidade Federal de São Paulo - UNIFESP, São Paulo/SP. - Departamento de Fisiologia Cardiovascular

Poster 124 Neurobehavioral and autonomic dysfunction in obstructive sleep apnea Idiaquez J1, Del Rio R2, Iturriaga R2, Santin J3, santos I1 - 1Universidad de Valparaiso - Catedra de Neurologia; 2P Universidad Catolica de chile - Laboratory of Neurobiology; 3P Universidad Catolica de Chile - Centro del sueño

Poster 125 Electrophysiological properties of expiratory and pre-sympathetic neurons in the ventrolateral medulla of rats submitted to chronic intermittent hypoxia. MORAES DJ1, Zoccal DB2, Machado BH3 - 1FACULDADE DE MEDICINA DE RIBEIRÃO PRETO/USP - DEPARTAMENTO DE FISIOLOGIA; 2Federal University of Santa Catarina - Dept Physiological Sciences; 3Faculdade de Medicina de Ribeirão Preto-USP - Fisiologia

Poster 126 Parasympathetic and Sympathetic Involvement in Obstructive Sleep Apnea Rothstein M1, Pereira E2, Baker S2, Arora R3, Bhatkar V4, Colombo J4 - 1Pulmonary & Critical Care Assoc - Jacksonville, FL, USA; 2Baker-Gilmour Cardiovascular Institute - Jacksonville, FL, USA; 3The Chicago Medical School - North Chicago, IL, USA; 4ANSAR Medical Technologies, Inc. - Philadelphia, PA, USA

Poster 127 Sympathetic Involvement in Sleep Medicine, Cardiovascular Implications Edward Pereira1, Baker S1, Rothstein M2, Arora R3, Bhatkar V4, Colombo J5 - 1Baker-Gilmour Cardiovascular Institute - Cardiology; 2Pulmonary & Critical Care Assoc - Pulmonology; 3The Chicago Medical School - Cardiology; 4ANSAR Medical

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Technologies, Inc. - BioMedical Engineering; 5ANSAR Medical Technologies, Inc. - Medical Director

Poster 128 Inhaled beta2-adrenorecptor agonist elicits hypecoagulability state Jacob G1, Ali-Saleh M2, Sarig G3, Brenner B3 - 1Medicne F - Tel Aviv Sourasky Medical Center, Faculty of Medicine, Tel Aviv University; 2Faculty of Medicine, IIT Technion, Haifa, Israel - Hematology; 3Rambam Medical Center, Haifa, Israel - Hematology

POSTER SESSION III Thursday, September 15, 2011 11:00-13:00 Autonomic Dysregulation in Myocardial Infarction & Heart Failure Poster 129 Inverse association between systolic function and sodium and water intake

in chronic aortic regurgitation Leme GA1, Tardivo ACB1, Roscani MG2, Matsubara LS2, Matsubara BB2, De Gobbi JIF1 - 1UNESP/IBB - Fisiologia; 2UNESP/FMB - Clínica Médica

Poster 130 Chronic treatment with low carvedilol dose improves blood pressure variability in rats with myocardial infarction Dantas EM1, Pimentel EB1, Andreão RV2, Cichoni BS3, Goncalves CP1, Zaniqueli D1, Baldo MP1, Rodrigues, SL1, Mill JG1 - 1Federal University of Espírito Santo - Physiological Sciences; 2Federal Institute of Espírito Santo - Electrical Engineering; 3Federal University of Espírito Santo - Computer Science

Poster 131 Symbolic analysis of cardiac autonomic modulation in coronary artery disease patients with and without acute myocardial infarction. Neves VR1, Takahashi ACM2, Santos-Hiss MDB2, Moura SCG2, Silveira RE2, Karsten M3, Borghi-Silva A4, Porta A5, Montano N6, Catai AM2 - 1Federal University of São Carlos - Physioterapy Department; 2Federal University of São Carlos - Physiotherapy Department; 3Federal University of Sao Carlos - Physiotherapy Department; 41Federal University of São Carlos - Physiotherapy Department; 5University of Milan - Department of Technologies for Health; 6University of Milan - Department of Clinical Sciences

Poster 132 Sympathetic activation after myocardial infarction in the rat: role of the arterial baroreflex, cardiac afferent reflexes and sex Barrett CJ1, Pinkham MI1 - 1The University of Auckland - Department of Physiology

Neuro-Immunomodulation & Control of Body Temperature Poster 133 Tumor Necrosis Factor stimulation of vagal afferent terminal calcium is blocked by

cannabinoids Rogers RC1, Hermann GE2 - 1Pennington Biomedical Research Center - Laboratory of Autonomic Neuroscience; 2Pennington Biomedical Research Center - Autonomic Neuroscience

Poster 134 Changes in expression and distribution patterns of Mas-related gene receptors in the murine ileum caused by intestinal inflammation Avula LR1, Van Nassauw L2, Stuyven E3, Buckinx R1, Alpaerts K1, Adriaensen D1, Favoreel H3, Cox E3, Timmermans JP3 - 1Laboratory of Cell Biology and Histology - Department of Veterinary Sciences; 2Laboratory of Cell Biology and Histology and

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Laboratory of Human Anatomy & Embryology - Department of Veterinary Sciences and Department of Antwerp Surgical Training, Anatomy and Research Center; 3Laboratory of Immunology - Department of Virology,Parasitology and Immunology

Poster 135 Cross talk between nitric oxide and carbon monoxide in the rat locus coeruleus during fever. Soriano RN1, Kwiatkoski M2, Batalhao ME1, Branco LGS3, Carnio EC1 - 1Escola de Enfermagem de Ribeirão Preto/USP - Dpto Enfermagem Geral e Especializada; 2Faculdade de Medicina de Ribeirão Preto/USP - Dpto Fisiologia; 3Faculdade de Odontologia de Ribeirão Preto/USP - Dpto Morfologia, Estomatologia e Fisiologia

Poster 136 Identifying rat sympathetic neurons that regulate immune function Bratton B1, Martelli D1, McKinley MJ1, Trevaks D1, McAllen RM1 - 1Florey Neuroscience Institutes - Systems Neurophysiology

Poster 137 Central alpha2-adrenoceptors mediate the inhibitory effect of lipopolysaccharide on sodium appetite independently from systemic inhibitory factors in rats De Luca Jr LA1, Almeida RL2, David RB1, Constancio J3, Fracasso JF4, Menani JV5 - 1UNESP - Faculdade de Odontologia de Araraquara - Fisiologia e Patologia; 2UNESP - Fisiologia e Patologia; 3UNESP-Faculdade de Odontologia de Araraquara - Fisiologia e Patologia; 4UNESP- Faculdade de Ciências Farmacêuticas - Araraquara; 5FOAr, UNESP - Fisiologia e Patologia

Poster 138 Leptin amplifies the action of thyrotropin releasing hormone in the nucleus of the solitary tract: implications for thermogenesis Hermann GE1, Rogers RC2 - 1Pennington Biomedical Research Center - Autonomic Neuroscience; 2Pennington Biomedical Research Center - Laboratory of Autonomic Neuroscience

Poster 139 Systemic vascular resistance does not increase during lower-body negative pressure in the heat stressed human Crandall CG1, Ganio MS1, Overgaard M2, Seifert T2, Secher NH2 - 1Texas Health Presbyterian Hospital Dallas - Institute for Exercise and Environmental Medicine; 2University of Copenhagen - Department of Anesthesia

Poster 140 Stress-induced hyperthermia is not mediated by interscapular brown adipose tissue in mice Vianna DML1, Carrive P1 - 1University of New South Wales - Medical Sciences

Poster 141 Selective brain cooling in the febrile sheep McKinley MJ1, Mathai M1, May CN1, McAllen RM1 - 1University of Melbourne - Florey Neuroscience Institutes

Poster 142 Orexin activates brown adipose tissue (BAT) thermogenesis in the rat Domenico T1, Madden CJ1, Morrison SF1 - 1Oregon Health & Science University - Neurological Surgery

Poster 143 Tail skin vasoconstriction during conditioned fear in the rat is mediated by the ventrolateral periaqueductal gray, not the dorsal tuberal hypothalamus. Luong L.N.L1, Vianna DML1, Carrive P1 - 1University of New South Wales - School of Medical Sciences

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Poster 144 Progressive increase in renal sympathetic nerve activity during development of cold-induced hypertension in rats Miki K1, Yagi K1, Yoshimoto M1 - 1Nara Women's University - Department of Integrative Physiology

Poster 145 Atypical antipsychotics cause an acute increase in cutaneous hand blood flow in patients with schizophrenia Blessing, W.W.1 - 1Flinders University - Human Physiology

Postural Orthostatic Tachycardia Syndrome (POTS)

Poster 146 Postural orthostatic tachycardia syndrome, chromatin regulation and the noradrenaline transporter gene Bayles R1 - 1BakerIDI Heart and Diabetes Institute - Human Neurotransmitters Laboratory

Poster 147 Effect of Fludrocortisone Acetate on Nausea and Autonomic Function during Tilt in Children with Postural Orthostatic Tachycardia Syndrome Shaltout HA1, Diz DI2, Fortunato JE3 - 1Wake Forest University, School of Medicine - Hypertension and Vascular Research Center; 2Wake Forest University - Hypertension and Vascular Research Center; 3Wake Forest University, School of Medicine - Department of Pediatrics, Division of Pediatric Gastroenterology

Poster 148 Actigraphy documented sleep problems in patients with postural tachycardia syndrome Wakwe C1, Bagai K2, Paranjape SY1, Farley MG1, Black BK1, Biaggioni I3, Robertson D4, Raj SR3 - 1Vanderbilt University - Medicine; 2Vanderbilt University - Neurology; 3Vanderbilt University - Medicine & Pharmacology; 4Vanderbilt University - Medicine, Pharmacology & Neurology

Poster 149 Neuroendocrine dysfunction in patients with postural orthostatic tachycardia syndrome Shomali ME1, Khurana RK1 - 1Union Memorial Hospital - Medicine

Poster 150 Neuropathic versus hyperadrenergic postural ortostatic tachycardia syndrome: time and frequency domain analysis. Park KJ, Low PA1, Singer W1, Figueroa JJ2, Sletten DM1, Opfer-Gehrking TL1, Zeller AD1 - 1Clinical Autonomic Research Laboratory - Department of Neurology, Mayo Clinic, Rochester, MN, U.S.A. ; 2Clinical Autonomic Research Laboratory - Clinical Autonomic Research Laboratory, Department of Neurology, Mayo Clinic, Rochester, MN, U.S.A.

Poster 151 The effects of the somatostatin analogue, octreotide, on orthostasis before and after food ingestion, in the Postural Tachycardia Syndrome Iodice V1, Low DA1, Mathias CJ1 - 1Autonomic and Neurovascular Medicine Unit, St Mary’s Hospital, Imperial College London - Autonomic Unit, National Hospital for Neurology and Neurosurgery, Institute of Neurology, University College London

Orthostatic Hypotension, Syncope & Cerebral Circulation Poster 152 Extracranial circulation affects near infrared spectroscopy assessment of

cerebral blood volume and oxygenation during neurovegetative tests CANOVA D1, Roatta S2, Micieli G3, Bosone D1 - 1IRCCS National Neurological

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Institute, “C.Mondino Foundation”, Pavia, Italy - Neurovascular Laboratory; 2University of Torino, Torino, Italy - Dept. of Neuroscience, Physiology Div.; 3IRCCS National Neurological Institute, “C.Mondino Foundation”, Pavia, Italy - Dept. of Emergency Neurology

Poster 153 Comparison of transcranial Doppler (TCD) and near infrared spectroscopy (NIRS) measurements during head-up tilt (HUT) in patients with neurally-mediated syncope (NMS) Schondorf R1, Eisenberg E2, Ehrlich E2, Benoit J2 - 1McGill University - Neurology; 2Jewish General Hospital - Neurology

Poster 154 Nonlinear profile of cerebral autoregulation dynamics- effects of stroke Hu K1, Lo MT2, Liu Y3, Peng CK4, Novak V5 - 1Division of Gerontology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA - Division of Sleep Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA - Research Center for Adaptive Data Analysis and Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, ROC; 2Division of Gerontology and Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA - Research Center for Adaptive Data Analysis and Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, ROC; 3DynaDx Corporation - Mountain View, CA; 4Division of Interdisciplinary Medicine & Biotechnology and Margret & H.A. Rey Institute for Nonlinear Dynamics in Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA - Research Center for Adaptive Data Analysis and Center for Dynamical Biomarkers and Translational Medicine, National Central University, Chungli, Taiwan, ROC; 5National Central University, Chungli, Taiwan, ROC - Research Center for Adaptive Data Analysis and Center for Dynamical Biomarkers and Translational Medicine

Poster 155 Brain Freeze Induced Changes in Cerebral Blood Flow Falvo MJ1, Blatt M2, Jasien JJ1, Deegan BM3, OLaighin G3, Serrador JM4 - 1VA NJ Health Care System - War Related Illness & Injury Study Center; 2Department of Veterans Affairs - War Related Illness and Injury Study Center; 3National University of Ireland Galway - Electrical & Electronic Engineering; 4Veterans Administration Health System - War Related Illness & Injury Study Center

Poster 156 Cerebral Blood Flow Decreases Prior to Nausea during Off-Vertical Axis Rotation Blatt M1, Falvo MJ1, Jasien JJ1, Wood SJ2, Serrador JM3 - 1VA NJ Health Care System, East Orange, NJ - War Related Illness & Injury Study Center; 2NASA Johnson Space Centre & Universities Space Research Association, Houston, TX - -; 3VA NJ Health Care System, East Orange, NJ, War Related Illness & Injury Study Center - Harvard Medical School, Boston, MA

Poster 157 Water: A new treatment for Blood Phobia Syncope Chih Cherng Lu1 - 1Tri-Service General Hospital - Anesthesiology

Poster 158 ROLE OF EXCITATORY PATHWAYS IN THE PARAVENTRICULAR NUCLEUS ON AUTONOMIC RESPONSE TO ORTHOSTATIC STRESS IN UNANESTHETIZED RATS Andrade O1, RAQUEL HA1, Fontes MAP2, Martins-Pinge MC2 - 1Universidade Estadual de Londrina - Ciências Fisiológicas; 2Universidade Federal de Minas Gerais - Fisiologia e Biofísica

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Poster 159 Differences in autonomic balance in patients with cardioinhibitory and vasodepressor type of reflex syncope during head-up tilt test and active standing. Holmegard HN1, Benn M2, Kaijer M3, Haunsø S4, Mehlsen J3 - 1Rigshospitalet, Copenhagen University Hospital - Laboratory of Molecular Cardiology; 2Herlev Hospital, Copenhagen University Hospital - Department of Clinical Biochemistry; 3Frederiksberg Hospital - Coordinating Research Centre; 4Rigshospitalet, Copenhagen University Hospital - Department of Cardiology

Poster 160 Epidemiology of orthostatic syndromes in syncope patients Smith JE1, Bena J2, Saju L1, Fouad-Tarazi FM3 - 1Cleveland Clinic - Cardiovascular Medicine; 2Cleveland Clinic - Quantitative Health Sciences; 3The Cleveland Clinic - Center for Syncope and Autonomic Disorders

Poster 161 PARAVENTRICULAR NUCLEUS OF HYPOTHALAMUS MODULATES AUTONOMIC RESPONSE TO ORTHOSTATIC STRESS IN UNANESTHETIZED WISTAR RATS. Andrade O1, Fontes MAP2, Martins-Pinge MC2 - 1Universidade Estadual de Londrina - Ciências Fisiológicas; 2Universidade Federal de Minas Gerais - Fisiologia e Biofísica

Poster 162 Somatic vigilance: an unrecognized cause of orthostatic intolerance Martinez JM1, Norcliffe-Kaufmann LJ2, Acosta J3, Adhikari I3, Kaufmann H3 - 1New York University Medical Center - Neurology; 2New York University School of Medicine - Physiology & Neuroscience; 3NYU Medical Center - Neurology

Poster 163 Duration of Treatment for Neurogenic Orthostatic Hypotension Shibao C1, Biaggioni I1, M.R. Griffin2, C.G. Grijalva2 - 1Vanderbilt University - Medicine; 2Vanderbilt University - Preventive Medicine

Poster 164 Time course of B-type natriuretic peptides changes after ventricular fibrillation in humans: relationship with cardiac syncope Costantino G1, Solbiati M1, Sagone A2, Vago T3, Pisano G4, Barbic F5, Dipaola F6, Casazza G7, Viecca M2, Furlan R8 - 1"L.Sacco" Hospital, Milan, Italy - Internal Medicine 2; 2"L.Sacco" Hospital, Milan, Italy - Cardiology; 3"L.Sacco" Hospital, Milan, Italy - Laboratory of Endocrinology; 4"L.Sacco"Hospital, Milan, Italy - Internal Medicine 2; 5"Bolognini" Hospital, Neuroscience Research Association, Seriate (BG), Italy - Internal Medicine; 6"Sesto S. Giovanni" Hospital, Sesto S.Giovanni, Milan, Italy - Internal Medicine; 7"L.Sacco" Hospital, University of Milan - Medical Statistics, Clinical Science; 8"Bolognini" Hospital, Seriate (BG), University of Milan, Italy - Internal Medicine

Poster 165 Ways to faint study: the sequel Jardine DL1, van Lieshout JJ2, Krediet CTP2, Wieling W2 - 1Christchurch Hospital, NZ - Department of General Medicine; 2Academic Medical Centre, Amsterdam, The Netherlands - -

Poster 166 3,4 Diaminopyridine Improves Orthostatic Blood Pressure and Symptoms in Neurogenic Orthostatic Hypotension Singer W1, Opfer-Gehrking TL1, Gehrking JA1, Figueroa JJ1, Sandroni P1, Low PA1 - 1Mayo Clinic Rochester, MN - Neurology

Poster 167 Chronic monitoring of brain tissue oxygen in freely moving rats from a fully implanted telemetry system Russell D1, Garry E2, Taberner A1, Budgett Dm1, Malpas SC3 - 1University of Auckland - Auckland Bioengineering Institute; 2BlueBox Sensors - Dublin, Ireland; 3University of Auckland - Physiology

Poster 168 Investigating syncope in children and adolescents: preliminary observations Protheroe CL1, Albaro C2, Roller JM1, Gibbs K2, Sanatani S2, Claydon VE3 - 1Simon Fraser University - Department of Biomedical Physiology and Kinesiology; 2BC Children's Hospital - Heart Centre; 3Simon Fraser University/University of British

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Columbia - Department of Biomedical Physiology and Kinesiology/International Collaboration On Repair Discoveries

Autonomic Neuropathies and Responses to Nerve Injury Poster 169 The prognosis and spectrum of disease in treatment induced diabetic

neuropathy, a painful autonomic neuropathy Gibbons CH1, Freeman R1 - 1Beth Israel Deaconess Medical Center, Harvard Medical School - Neurology

Poster 170 Perivascular sympathetic neuropathy in the streptozotocin type I diabetic rat model Johansen NJ1, Abela R1, Brock JA1 - 1University of Melbourne - Anatomy and Cell Biology

Poster 171 The severity of diabetic autonomic neuropathy affects pressure but not metabolic cerebral autoregulation Yeh SJ1, Chiu C.C.2, Liau B.Y.3 - 1Cheng Ching Hospital - Neurology; 2Feng Chia University - Graduate Institute of Electrical and Communications Engineering; 3Hungkuang University - Department of Biomedical Engineering

Poster 172 Y1R-mediated regulation of sciatic nerve blood supply in wistar kyoto rats Twynstra J1, Lacefield J.C.2, Shoemaker JK3 - 1The University of Western Ontario - School of Kinesiology; 2Robarts Research Institute - The University of Western Ontario; 3The University of Western Ontario - Kinesiology

Poster 173 The Laser Doppler Imaging Axon-Reflex Flare Area/Latency Ratio: A Novel Measure of Neurovascular C-Fiber Function Siepmann T1, Illigens BMW1, Freeman R1, Gibbons CH1 - 1Beth Israel Deaconess Medical Center, Harvard Medical School - Neurology

Poster 174 The quantification of cutaneous autonomic pilomotor innervation Gibbons CH1, Wang N1, Hovaguimian A1, Illigens BMW1, Freeman R1 - 1Beth Israel Deaconess Medical Center, Harvard Medical School - Neurology

Poster 175 The role of capsaicin-sensitive sensory neurons in autonomic dysreflexia in the spinal cord injured-rat Ramer LM1, AP van Stolk2, Inskip JA3, Ramer MS1, Krassioukov AV4 - 1University of British Columbia - International Collaboration on Repair Discoveries; 2UBC - ICORD; 3Simon Fraser University - Biomedical Physiology and Kinesiology; 4University of British Columbia - Physical Medicine and Rehabilitation

Poster 176 Transient changes in BDNF parallel plasticity observed in the IML following distal axon injury Coulibaly AP1, Walsh BF1, Isaacson LG1 - 1Miami University - Zoology

Poster 177 Spectral analysis of cardiovascular control after spinal cord injury in rats: Effect of time post-injury Inskip JA1, Ramer LM2, Ramer MS2, Krassioukov AV3, Claydon VE3 - 1Simon Fraser University/University of British Columbia - Biomedical Physiology and Kinesiology/International Collaboration on Repair Discoveries; 2University of British Columbia - International Collaboration on Repair Discoveries/Zoology; 3University of British Columbia - Department of Physical Medicine and Rehabilitation/International Collaboration on Repair Discoveries

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Poster 178 Autonomic Function & Symptoms of Orthostatic Hypotension in Wheelchair Athletes Wong SC1, Mills P2, Tawashy A3, Mikhail D4, OConnor R5, Warburton DER1, Taunton J5, Eng J3, Campbell D6, Krassioukov AV2 - 1University of British Columbia - Experimental Medicine; 2University of British Columbia - Physical Medicine and Rehabilitation; 3University of British Columbia - Rehabilitation Sciences; 4University of Western Ontario - Schulich School of Medicine and Dentistry ; 5University of British Columbia - Medicine; 6BC Wheelchair Sports - BC Wheelchair Sports

Poster 179 Does autonomic dysfunction play a role in the development of cardiovascular disease after spinal cord injury? Ravensbergen HJC1, Sahota IS2, Lear SA3, Krassioukov AV4, Claydon VE5 - 1Simon Fraser University/ University of Brithish Columbia - Biomedical Physiology and Kinesiology/ International Collaboration On Repair Discoveries; 2Simon Fraser University/ University of British Columbia - Biomedical Physiology and Kinesiology/International Collaboration On Repair Discoveries; 3Simon Fraser University - Biomedical Physiology and Kinesiology/Faculty of Health Science; 4University of British Columbia - Physical Medicine and Rehabilitation; 5Simon Fraser University/University of British Columbia - Biomedical Physiology and Kinesiology/International Collaboration On Repair Discoveries

Synucleinopathies & Severe Genetic Autonomic Disorders

Poster 180 Cardiac sympathetic denervation in symptomatic and asymptomatic carriers of the E46K mutation in the synuclein gene Tijero B1, Gomez-Esteban JC2, Kaufmann H3, Llorens V4, Zarranz JJ5 - 1Cruces Hospital - Movement disorders and autonomic Unit. Department of Neurology; 2Osakidetza. hospital of cruces - Neurology; 3NYU medical center - Neurology; 4Cruces Hospital - Service of Nuclear Medicine; 5Cruces Hospital - Neurology

Poster 181 Small Fiber Sensory Neuropathy in Parkinson Disease with Autonomic Failure Novak P1, Ravin P1, Hays AP2, Qin L1 - 1University of Massachusetts - Neurology; 2Therapath - NY

Poster 182 Mice overexpressing human alpha synuclein in oligodendrocytes do not develop an autonomic failure phenotype Tank J1, daCosta-Goncalves2, Ubhi K3, Rockenstein E3, Diedrich A4, Masliah E3, Jordan J1 - 1Hannover Medical School - Institute of Clinical Pharmacology; 2Max Delbrueck Center for Molecular Medicine, Berlin-Buch, Germany - Leibnitz Institute for Molecular Pharmacology; 3University of California, San Diego, La Jolla, USA - Department of Neurosciences; 4Vanderbilt University School of Medicine, Nashville, TN, USA - Department of Medicine, Division of Clinical Pharmacology, Autonomic Dysfunction Service

Poster 183 The norepinephrine paradox in hereditary sensory and autonomic neuropathy type IV Norcliffe-Kaufmann LJ1, Axelrod FB2, Kaufmann H3 - 1New York University School of Medicine - Department of Physiology and Neurosciences; 2New York University School of Medicine - Departments of Pediatrics and Neurology; 3New York University School of Medicine - Department of Neurology

Poster 184 Is end-tidal CO2 a valid measurement to assess hypoventilation in patients with familial dysautonomia? Perez MA1, Norcliffe-Kaufmann LJ2, Reyes J3, Axelrod FB4, Kaufmann H3 - 1Dysautonomia Center - Neurology; 2New York University School of Medicine - Physiology & Neuroscience; 3New York University School of Medicine - Neurology; 4New York University School of Medicine - Pediatrics and Neurology

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Poster 185 Improving the Quality of Autonomic Consultations through Voice Recognition Dictation Technology Cheshire WP1 - 1Mayo Clinic - Neurology

POSTER SESSION IV Friday, September 16, 2011 11:00-13:00

Mechanisms Regulating Sympathetic Nerve Activity Poster 186 Activity of hypothalamic paraventricular nucleus neurons supports non-

respiratory/non-cardiac rhythmic sympathetic nerve activity in water deprived rats Holbein W1, Toney GM1 - 1Univ. of Texas Health Science Center at San Antonio - Department of Physiology

Poster 187 Respiratory modulation of muscle sympathetic nerve activity is not increased in patients with essential hypertension or chronic obstructive pulmonary disease. Fatouleh R1, Macefield V.G.1 – 1University of Western Sydney – School of Medicine

Poster 188 Increasing intensity of hypoxia augments activation of hypothalamic paraventricular nucleus-projecting neurons in the caudal ventrolateral medulla King T.L.1, Heesch CM2, Friskey S.A.1, Ruyle BC3, Kline DD4, Hasser EM1 - 1University of Missouri - Biomedical Sciences/DCRC; 2University of Missouri - Dalton Cardiovascular Research Ctr; 3University of Missouri - DCRC; 4University of Missouri - Biomed Sci/DCRC

Poster 189 Projections from nucleus raphe obscurus to the caudal pressor area in the rat Silva NF1, Meneguzzi VC1, Pires JGP2, Futuro Neto HA3 - 1UFES - Morfologia; 2UNESC, UNIVIX - Farmacologia; 3EMESCAM, UFES, UNIVIX - Morfologia

Poster 190 Sources of tonic inhibition to the rostral ventrolateral medulla in the rattus norvegicus Bowman BR1, Kumar NN1, Goodchild AK1 - 1Macquarie University - Australian School of Advanced Medicine

Poster 191 Interactions of ATP- and glutamate-induced sympathoexcitation at the paraventricular nucleus level of rat Ferreira-Neto HC1, Yao ST2, Antunes VR1 - 1Institute of Biomedical Sciences, University of Sao Paulo - Physiology and Biophysics; 2University of Melbourne - Florey Neurosciences Institute

Poster 192 Rapid onset sympathoexcitation during static handgrip in older hypertensive adults Greaney JL1, Fadel PJ2, Farquhar WB1 - 1University of Delaware - Kinesiology and Applied Physiology; 2University of Missouri - Medical Pharmocology and Physiology

Poster 193 Balancing resting arterial pressure and sympathetic nerve activity: influence aging in women Hart EC1, Charkoudian N2, Wallin BG3, Curry TB1, Joyner, Michael4 - 1Mayo Clinic - Department of Anethesia; 2Mayo Clinic - Department of Physiology and Biomedical Engineering; 3Sahlgrenska Academy - Institute of Neuroscience and Physiology; 4Mayo Cinic - Department of Anethesia

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Poster 194 Blockade of orexin receptors differentially modulate sympathetic and respiratory responses to hypothalamic activation in rats Dampney RAL1, Horiuchi J1, Carrive P2, Dampney RAL1 - 1University of Sydney, NSW 2006 - School of Medical Sciences and Bosch Institute; 2University of NSW, NSW 2052 - School of Medical Sciences

Poster 195 Evidence that neurons of retrotrapezoid nucleus contributes to active expiration but not sympatho-excitation in response to peripheral chemoreflex activation in rat in situ preparations. Zoccal DB1, Moaes DJA2, Dias MB2, Cavalcanti-Kwiatkoski R2, Machado BH2 - 1Federal University of Santa Catarina - Dept Physiological Sciences; 2School of Medicine of Ribeirão Preto, University of São Paulo - Physiology

Poster 196 Sympathetic, endothelial and arterial dysfunction in adult patients with Fontan circulation Lambert E1, Dudakem Y2, Cheung M3, Sari C4, Schlaich, M4, Inman J4, Ahimastos A5, Eikelis N4, Patak A6, Grigg L7, Lambert G4 - 1Baker IDI Australia - Human Neurotransmitters; 2Royal Children Hospital - Cardiac surgery; 3Royal Children Hospital - Department of Cardiology; 4Baker IDI - Human Neurotransmitters; 5Baker IDI - Department of Physiology; 6Unité INSERM U 858 France - Service de Pharmacologie Clinique; 7Royal Melbourne Hospital - Department of Cardiology

Poster 197 Vestibular influences on muscle and skin sympathetic nerve activity: low-frequency sinusoidal galvanic vestibular stimulation reveals two peaks of modulation Hammam E1, Macefield V.G.1 - 1University of Western Sydney - School of Medicine

Poster 198 Peripheral chemoreflex induced long term facilitation of sympathetic nerve activity: role of adrenomedullin in the rostral ventrolateral medulla. Colombari D.S.A.1, Colombari E1, Murphy D2, Paton JFR3 - 1School of Dentistry, UNESP - Araraquara, SP, Brazil - Department of Physiology & Pathology; 2University of Bristol - Henry Wellcome L.I.N.E; 3University of Bristol - Physiology & Pharmacology

Poster 199 Peripheral chemoreflex stimulation and adrenomedullin in the rostral ventrolateral medulla induces long-term facilitation of sympathetic activity in rats exposed to chronic intermittent hypoxia Colombari E1, Colombari D.S.A.1, Zoccal DB2, Costa-Silva J.H.3, Moraes D.J.3, Paton JFR4, Murphy D5, Machado BH3 - 1School of Dentistry, UNESP - Araraquara, SP, Brazil - Department of Physiology & Pathology; 2Federal University of Santa Catarina - Dept Physiological Sciences; 3School of Medicine of Ribeirão Preto, University of São Paulo, Brazil - Department of Physiology; 4University of Bristol - Physiology & Pharmacology; 5University of Bristol - Henry Wellcome L.I.N.E

Poster 200 Patterning of Sympathetic Vasomotor activity in response to Paraventricular Nucleus of the Hypothalamus disinhibition: Role of Spinal Cord Vasopressingerg Synapses. Silva AM1, Bergamaschi CT2, Campos RR2 - 1UNIFESP - Escola Paulista de Medicina - Fisiologia Cardiovascular e Respiratória; 2Unifesp - EPM - Fisiologia Cardiovascular e Respiratória

Poster 201 Vestibular entrainment of sympathetic nerve activity by low-frequency sinusoidal acceleration in the horizontal plane Dawood T1, Hammam E1, Macefield V.G.1 - 1University of Western Sydney - School of Medicine

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Poster 202 Spinally projecting and vasopressin containing cells in the hypothalamic paraventricular nucleus of female rats are activated by relaxin in the forebrain circulation Brown RJ1, Coldren KM2, King TL2, Kline DD3, Hasser EM3, Heesch CM4 - 1University of Missouri - Interdisciplinary Neuroscience Program; 2University of Missouri - Biomedical Sciences; 3University of Missouri - Biomed Sci/DCRC; 4University of Missouri - Biomed Sci/DCRC/INP

Poster 203 A preliminary study on the arrangement of sympathetic fibres within the human common fibular nerve Tompkins R1, Melling J2, Shoemaker JK3, Wilson TD1 - 1University of Western Ontario - Department of Anatomy and Cell Biology, Schulich School of Medicine and Dentistry; 2University of Western Ontario - Faculty of Health Sciences, School of Kinesiology; 3University of Western Ontario - Faculty of Health Sciences, School of Kinesiology and Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry

Heart Rate Variability, Sympathovagal Balance & Cardiovagal Nerve Activity

Poster 204 Influence of sequential breathing on heart rate variability tests of cardiovagal function Shields RW1 - 1Cleveland Clinic - Neurology

Poster 205 Effects of acute hypertonic saline infusion in heart rate variability in male Wistar rats Farah HMAT1, Almeida RL1, Mostarda CT2, Farah VMA3, Sato MA1, Irigoyen MC2, Colombari E4 - 1Faculdade de Medicina do ABC - Morfologia e Fisiologia; 2Incor - USP - Laboratório de Hipertensão; 3Universidade Presbiteriana Mackenzie - Fisiologia; 4UNESP - Fisiologia e Patologia

Poster 206 Determination of sympathetic and parasympathetic modulation of pupillary diameter by pharmacological blockade Hilz MJ1, Cimpianu CL2, Tillmann A2, Riss S2, Moeller S2, DeFina PA3, Koehn J2 - 1New York University, New York, NY, USA - Depts. of Neurology, Medicine, Psychiatry; 2University of Erlangen-Nuremberg, Erlangen, Germany - Dept. of Neurology; 3International Brain Research Foundation, Edison, NJ, USA - IBRF

Poster 207 Relation of heart rate variability to endothelial function in healthy subjects- dependence upon cardiac cycle length Pinter A1, Horvath T1, Kollai M1 - 1Semmelweis University - Institute of Human Physiology and Clinical Experimental Research

Poster 208 Does the dorsal motor nucleus of the vagus control cardiac chronotropism in the rat? Pickering AE1, Salo LM1, Hewinson J1, Ambler MT1, Paton JFR1, McAllen RM2 - 1University of Bristol - Physiology & Pharmacology; 2Florey Neuroscience Institute - Systems Neurophysiology

Poster 209 Parasympathetic reactivation after a cardiopulmonary exercise test in humans is not associated with the endothelial nitric oxide synthase gene polymorphisms Barbosa TC1, Pereira FS1, Silva BM1, Neves FJ1, Rocha NG1, Sales AR1, Cardoso FT1, Ribeiro GS2, Nobrega AC1 - 1Fluminense Federal University - Physiology and Pharmacology; 2Fluminense Federal University - Pathology

Poster 210 Effect of tDCS on parasymphatetic reativaction after submaximal exercise MONTENEGRO RA1, Okano, A.H.2, Fontes, E.B.3, Cunha, F.A.4, Porto, F.5, Gurgel, J.L.6, Farinatti PTV7 - 1Laboratory of Integrative Biology of Exercise (LABIEX), Federal University of Rio Grande do Norte, Natal, Brazil. - Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute,

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State University of Rio de Janeiro, Rio de Janeiro, Brazil.; 2Laboratory of Integrative Biology of Exercise (LABIEX), Federal University of Rio Grande do Norte, Natal, Brazil. - Physical Education Departament. University of Rio Grande do Norte. Natal. Brazil; 3Laboratory of Integrative Biology of Exercise (LABIEX), Federal University of Rio Grande do Norte, Natal, Brazil. - Physical Education Faculty, State University of Campinas, Campinas, Brazil; 4Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil. - Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil.; 5Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil - Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil.; 6Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil - Physical Education Institute, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil; 7Physical Activity and Health Promotion Laboratory (LABSAU), Physical Education and Sports Institute, State University of Rio de Janeiro, Rio de Janeiro, Brazil. - Graduate Program in Physical Activity Sciences of the Salgado de Oliveira University, Rio de Janeiro, Brazil

Poster 211 Effects of Exercise Training on Heart Rate Recovery in Coronary Artery Disease Patients Neves VR1, Kiviniemi AM2, Hautala AJ2, Karjalainen J2, Catai AM1, Huikuri HV3, Tulppo MP2 - 1Federal University of São Carlos, São Carlos, SP, Brasil - Department of Physiotherapy; 2Verve Research, Oulu, Finland - Department of Exercise and Medical Physiology; 3University of Oulu, Finland - Division of Cardiology, Department of Internal Medicine

Poster 212 Reduced heart rate variability in the diabetic heart is reversed by inhibition of glycogen synthase kinase 3β activity Welzig CM1, Zhang Y2, Park H-J2, Picard K2, Galper JB2 - 1Medical University of South Carolina - Neurosciences; 2Tufts Medical Center, Boston, MA, USA - Molecular Cardiology Research Institute

Poster 213 GSK3β Regulates the Parasympathetic Response in the Heart via the Control of Sterol Response Element Binding Protein: A New Therapeutic Target For Cardiac Autonomic Neuropathy Zhang Y1, Welzig CM2, Park H-J1, Chuang Du3, Picard K1, Galper JB1 - 1Tufts Medical Center, Boston, MA, USA - Molecular Cardiology Research Institute; 2Medical University of South Carolina - Neurosciences; 3Tufts University School of Medicine, Boston, MA, USA - Center for Neuroscience Research, Department of Neuroscience

Poster 214 MORPHOLOGICAL REMODELING OF NUCLEUS AMBIGUUS (NA) PROJECTIONS TO CARDIAC GANGLIA IN STREPTOZOTOCIN (STZ)-INDUCED DIABETIC MICE Ai J1, Cheng Z1 - 1University of Central Florida - Biomolecular Science Center, Burnett School of Biomedical Science, College of Medicine

Poster 215 Parasympathetic Involvement in Sleep Medicine, Cardiovascular Implications Mitchell Rothstein1, Pereira E2, Baker S2, Arora R3, Bhatkar V4, Colombo J5 - 1Pulmonary & Critical Care Assoc - Pulmonology; 2Baker-Gilmour Cardiovascular Institute - Cardiology; 3The Chicago Medical School - Cardiology; 4ANSAR Medical Technologies, Inc. - BioMedical Engineering; 5ANSAR Medical Technologies, Inc. - Medical Director

Effects of Exercise Training and Other Behavioral Modifications

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Poster 216 AUTONOMIC CHANGES AFTER RESISTANCE EXERCISE IN INDIVIDUALS WITH UNTREATED STAGE 1 HYPERTENSION. Chrispino TC1, Barbosa TPC1, Neves FJ1, Nobrega AC2 - 1Fluminense Federal University, Niterói, RJ. - Graduate Program in Cardiovascular Sciences; 2Fluminense Federal University, Niterói, RJ. - Department of Physiology and Pharmacology

Poster 217 Diet and exercise training reduce blood pressure and restore alteration in autonomic modulation in women with prehypertension Sales ARK1, Neves FJ1, Silva BM1, Rocha NG1, Medeiros RF2, CASTRO RRT1, Nobrega AC1 - 1Fluminense Federal University - Physiology and Pharmacology; 2Fluminense Federal University - Physiology and Pharmacoogy

Poster 218 Sequential Effect Of Aerobic Training (T) On The Plasticity Of Central Oxytocinergic (Otergic) System In Normotensive And Hypertensive Rats. T. T. Zampieri1, S. D. Silva-Junior1, RUGGERI, A2, T. P. Alves1, Ceroni A3, J. E. Stern4, Michelini LC5 - 1ICB/USP - Fisiologia e Biofísica; 2Universidade de São Paulo - Fisiologia e Biofísica; 3USP - Fisiologia e Biofísica; 4MCG - Physiology; 5ICB - USP - Fisiologia e Biofísica

Poster 219 Effects Of Aerobic Training On Gabaergic And Glutamatergic Gene Expression Within The PVN And RVLM Of Rats RUGGERI, A1, T. T. Zampieri1, S. D. Silva-Junior1, Ceroni A1, Michelini LC1 - 1Universidade de São Paulo - Fisiologia e Biofísica

Poster 220 Aerobic Training Improves Microcirculation within the Nucleus Tractus Solitarii of Normotensive and Hypertensive Rats Jordao MT1, Cavalleri MT1, Burgi K1, Ceroni A1, Michelini LC1 - 1University of Sao Paulo - Department Physiology & Biophysics

Poster 221 Cardiac autonomic modulation after resistance exercise: comparison between genders Rezk CC1, Queiroz ACC2, Teixeira L2, Tinucci T2, Forjaz CLM2 - 1University Center FIEO - Physical Education Department; 2University of São Paulo - School of Physical Education and Sport

Poster 222 Swimming exercise in spontaneously hypertensive rats (SHR) changes the hemodynamic responses dependent on opioidergic pathways in the rostral ventrolateral medulla (RVLM) Almeida RL1, Ogihara CA1, Saviolli, I.H.1, Colombari E2, Sato MA1 - 1Faculdade de Medicina do ABC - Morfologia e Fisiologia; 2UNESP - Fisiologia e Patologia

Poster 223 Autonomic changes after sucessive bouts of maximal exercise in simulated rowing Soares PP1, Gonçalves TR1, Moraes Rde2, Barros RBM1, Pinto BS2, van Bavel D2, Tibiriça E2 - 1Fluminense Federal University - Laboratory of Exercise Physiology Experimental and Applied - Biomedical Institute; 2FIOCRUZ - Laboratory of Cardiovascular Physiopharmacology

Poster 224 Conditional Entropy Does Not Change After Eccentric Strength Training in Older Men Takahashi ACM1, Porta A2, Melo RC3, Quiterio RJ4, Silva E5, Borghi-Silva A1, Montano N6, Catai AM1 - 1Federal University of São Carlos - Physiotherapy Department; 2University of Milan - Department of Technologies for Health; 3University of São Paulo - School of Arts, Sciences and Humanities; 4UNESP - Univ Estadual Paulista - Physiotherapy Department; 5Methodist University of Piracicaba - Faculty of Health Sciences; 6University of Milan - Department of Clinical Sciences

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Poster 225 Chronic and acute effects of resistance training on autonomic modulation in elderly Queiroz ACC1, Kanegusuku, H1, COSTA LAR1, Wallerstein LF1, Dias da Silva VJ2, De Mello MT3, Ugrinowitsch C1, Forjaz CLM1 - 1University of São Paulo - School of Physical Education and Sport; 2Federal University of the Triângulo Mineiro - Physiology Division, Biological Science Department; 3Federal University of São Paulo - Psychobiology and Exercise Research Center

Poster 226 Comparison of affective responses in aerobic activities categorized by intensity, impulse training and duration Oliveira BRR1, Deslandes A2, Furtado ES3, Lemos FA1, Slama FA3, Santos TM1 - 1Universidade Gama Filho - Programa de Pós Graduação Stricto Sensu em Educação Física; 2UFRJ - IPUB; 3Universidade Gama Filho - Departamento de Educação Física

Poster 227 Acute yogic breathing increases forearm blood flow but does not alter blood pressure Wehrwein, Erica A1, Johnson1, Charkoudian N1, Wallin BG2, Joyner, Michael1 - 1Mayo Clinic - Anesthesiology; 2Sahlgrenska Academy - Institute of Neuroscience and Physiology

Poster 228 Cardiovascular effects after chronic administration of green tea in diabetic rats SANTOS F1, Mostarda CT2, Calassi N1, Dudas P1, Fiorino P1, Evangelista FS3, Irigoyen MC2, Farah VMA2 - 1Universidade presbiteriana Mackenzie - Metabolic Cardiovascular and Renal Physiopharmacology; 2Insituto do Coração (Incor), HC-FMUSP, São Paulo, SP - Div. de Experimentação; 3University of Sao Paulo (USP) - 3- School of Arts, Science and Humanitities

Autonomic Nervous System Effects on the Respiratory System

Poster 229 Role of carotid body chemoreceptors in cardiovascular adjustments induced by hypernatremia in rats Pedrino GR1, Rossi MV2, Schoorlemmer GHM2, Lopes OU2, Cravo SLD2 - 1UFG - Physiological Science; 2UNIFESP - Physiology

Poster 230 Airway constriction and cough induced by breathing warm humidified air in asthmatics: role of cholinergic mechanisms Lee LY1, Hayes D2 - 1University of Kentucky - Physiology; 2University of Kentucky - Pediatrics and Medicine

Poster 231 Can heart period influence respiration? Bertisch, SM1, Tan CO2, Taylor JA2 - 1Harvard Medical School - Division of General Medicine and Primary Care, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA; 2Harvard Medical School - Physical Medicine and Rehabilitation

Poster 232 Carotid Body Denervation Blocks Training Induces Resting Bradycardia and Reduces Oxytocin Immunoreactivity in Preautonomic PVN Subnuclei of Rats Cruz JC1, Ceroni A1, Cavalleri MT1, Michelini LC1 - 1University of Sao Paulo - Department Physiology & Biophysics

Poster 233 Protein kinase A inhibition in vivo depresses respiratory drive but not rhythm in central respiratory networks of adult rat Sousa LO1, Burke PGR1, Tallapragada VJ1, Goodchild AK1 - 1Macquarie University - Australian School of Advanced Medicine

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Poster 234 Evidence for neuroepithelial bodies (NEBs) as vagal mechanotransducers in the intrapulmonary mouse airway epithelium. Lembrechts R1, Brouns I1, Schnorbusch K1, Pintelon I1, Timmermans JP1, Adriaensen D1 - 1University of Antwerp - Laboratory of Cell Biology and Histology

Poster 235 Mouse pulmonary neuroepithelial bodies harbor a GABAergic signaling mechanism. Schnorbusch K1, Brouns I1, Lembrechts R1, Pintelon I1, Timmermans JP1, Adriaensen D1 - 1University of Antwerp - Laboratory of Cell Biology and Histology

Poster 236 Role of the retrotrapezoid nucleus phox2b-expressing neurons during mild-exercise in rats. Falquetto B1, Takakura AC2, Moreira TS1 - 1University of Sao Paulo - Physiology and Biophysics; 2University of Sao Paulo - Pharmacology

Poster 237 Acute, specific transgenic ‘silencing’ of Phox2b-expressing neurons in the caudal nucleus tractus solitarius reduces arterial pressure and respiration at rest and in response to hypercapnia in conscious rats Li A1, Abdala APL2, Paton JFR2, Nattie EE1 - 1Dartmouth Medical School - Physiology; 2University of Bristol - Physiology & Pharmacology

Poster 238 Localisation and function of muscarinic receptors in murine tracheal neurons Jositsch G1, Ringer C2, Wiegand S1, Hartmann P1, Krasteva G1, Schütz B2, Nassenstein C1, Wess J3, Weihe E2, Kummer W1 - 1Justus-Liebig-University Giessen - Institute for Anatomy and Cell Biology; 2Philipps-University Marburg - Institute for Anatomy and Cell Biology; 3National Institute of Diabetes and Digestive and Kidney Diseases - Molecular Signalling Section

Other Poster 239 Semaphorin 3F expression pattern coincides with the sympathetic nerve

degeneration induced by oestrogen in the rat uterus. Richeri A1, Chalar C2, Martínez G1, Brauer MM1 - 1Instituto de Investigaciones Biológicas Clemente Estable - Laboratory of Cell Biology; 2Facultad de Ciencias-UdelaR - Department of Biochemistry. Montevideo, Uruguay.

Poster 240 Superior ovarian nerve regulates ovarian estradiol secretion in rats Uchida S1, Kagitani F1, Hotta H1 - 1Tokyo Metropolitan Institute of Gerontology - Department of Autonomic Neuroscience

Poster 241 Complex Regional Pain Syndrome: a systemic disease of the autonomic nervous system? Chémali, KR1, Zhou, L1, Ianacci, S2, Chelimsky TC2 - 1Cleveland Clinic - Neurology; 2Case Western Reserve University - Neurology