CONTEMPORARY DEBATES IN HEART FAILURE AND HYPERTENSION

Joint Symposium of the Association of Black Cardiologists, the American Society of Hypertension and the American College of Cardiology

• Advances in Heart Failure For African Americans:

Paradigm Shift or Paradigm Drift?

• 2014 Evidence-Based Guideline For the Management

of High Blood Pressure: Did They Get It Right?

AG

EN

DA

• Case Presentation with Key Clinical Pearls

• Panel Discussion with Audience Question and Answer

DEBATES

• 8442 patients with class II-IV heart failure with LVEF 40% or less

• LCZ696 vs enalapril in addition to standard therapy

• 20% reduction in death and hospitalization

• Small number of Blacks enrolled

Advances in Heart Failure

For African Americans:

Paradigm Shift or Paradigm Drift?

PRO

Clyde W. Yancy

• 1050 AA patients with dilated ventricles and NYHA class III-IV heart failure

• Fixed dose hydralazine and isosorbide vs placebo

• 43% reduction in mortality

• 33% reduction in first hospitalization

• Surprisingly low utilization despite guideline recommendation

Advances in Heart Failure

For African Americans:

Paradigm Shift or Paradigm Drift?

CON

Elizabeth Ofili

Advances in Heart Failure

For African Americans:

Paradigm Shift or Paradigm Drift?

PRO CON

YANCY versus

OFILI

• BP goal <150/90mHg in patients 60 years or older without

renal disease or diabetes

• Higher than previous recommendation of <140/90mmHg

2014 Evidence-Based Guideline

For the Management of High Blood

Pressure: Did They Get It Right?

PRO

Joel Handler

Raising the SBP goal to 150 mm Hg in persons who are 60

years of age – especially in African Americans – may have

a substantial negative impact on gains that have been

made in the last several decades in the treatment of CVD.

2014 Evidence-Based Guideline

For the Management of High Blood

Pressure: Did They Get It Right?

CON

William Elliott

2014 Evidence-Based Guideline For

the Management of High Blood

Pressure: Did They Get It Right?

PRO CON

HANDLER versus

ELLIOTT

Case Presentation with Key Clinical Pearls

Domenic A. Sica

Panel Discussion with Audience Question and Answer