Welcome to IB 201!

Genetics and Evolution

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Instructors

Teaching Assistants

Moni Berg

Karen Cavey

Casey Funderburk

Beth Ruedi

LectureDr. Kim Hughes

(Genetics)Dr. Sydney Cameron

(Evolution)

LaboratoryDr. Kevin Dixon

Required Texts

Selected Chapters from “Essential Genetics”, by Russell, available online

“Evolutionary Biology”, by Freeman and Herron

Other reading material will be distributed in class or available on the course web site.

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How to access the chapters of the Genetics text online

Go to www.coursecompass.com. Once there you should register as a student. Enter your code to register and create a login and password.

Once you are logged in select IB 201 under the courses option.

Select “Biology Chapters” from the side menu. Scroll down until you get to “Genetics Appendix”.

6 chapters from the Genetics text (by Russell). You can download them and either view them on your computer or print them out.

Course Web Site

http://www.life.uiuc.edu/ib/201

Class schedule

Assigned readings

Homework assignments

Lecture notes

Powerpoint slides

Recommended problens

Course Pre-requisites

IB 150: Organismal and Evolutionary Biology

MCB 150: Molecular and Cellular Basis of Life

Review material available on the course web site: Basic Mendelian and Molecular Genetics

Grading

Lecture: 70% of grade; Laboratory: 30%

Lecture: 700 points total:

Two Midterms: 75 points each

Final Exam (cumulative): 100 points

Six Homework assignments: 75 pts ea

Online multiple-choice assignments:

access them from the course web site.

Extra Credit

Questions at beginning of class

Based on reading assignment

Answer due before class starts

2 pts each class (one-half letter grade)

Course Policies

NO MAKEUP EXAMSHW assignments posted on the course

web site, due before 9:00 am on due date. No extensions

Final: 1:30-4:30 pm Friday, May 6, in this room

Course Policies

NO MAKEUP EXAMSHW assignments posted on the course

web site, due before 9:00 am on due date. No extensions

Final: 1:30-4:30 pm Friday, May 6, in this room

How to succeed in this course

Come to class!Read the assigned material before classDownload lecture notes before class.Bring a calculator and scrap paper to

class.Do recommended problems: you will

see them again!Participate in class discussion

Don’t

Furiously take notes during classPut off the homework until the last

minutePut off doing recommended problems

until just before the exam

IB 201 Genetics and Evolution

Part 1 Genetics

Dr. Kim Hughes

465B Morrill Hall

kahughes@life.uiuc.edu

Office hours: Tu/Th after class or by appointment

Practice Quiz1. Round-seeded pea was crossed to a wrinkle-seeded pea all the

offspring were round. Diagram the cross and predict the ratio of wrinkled to round offspring in the F2 generation.

2. A round-seeded pea is crossed to a wrinkle-seeded pea. Half the offspring are round and half are wrinkled. What are the genotypes of the parents, the round F1 offspring, and the wrinkled F1 offspring?

3. True-breeding yellow, round plants were crossed to true breeding green, wrinkled ones. All F1 offspring are yellow and round. What are the genotypes of the parents and the F1 offspring? What phenotypes, and in what proportions, do you expect in the F2 generation?

4. A red snapdragon is crossed to a white snapdragon and all the offspring are pink. This is an example of what genetic property?

Practice Quiz5. A woman homozygous for the A allele of the ABO blood

group marries a man who is homozygous for the B locus. What is the blood group phenotype of their child? This is an example of what genetic property?

6. What is the most likely mode of inheritance illustrated by this pedigree?

7. The combined probability of two or more mutually exclusive events occurring is the ________ of their individual probabilities.

8. The joint probability of both of two independent events occurring is the _________ of their individual probabilities.

Terms you should know Gene

LocusAlleleDominanceRecessivenessWild typeMutationGenotypePhenotypeHomozygoteHeterozygoteMonohybridDihybrid

PleiotropyEpistasisAutosomeSex chromosomeHemizygousPleiotropyEpistasisHaploidDiploidNuclear DNAMitochondrial DNAChloroplast DNAChromosome

Homologous chromosomesSister chromatidsTetradMitosisMeoisisIndependent assortmentRecombinationCrossing overTranscriptionTranslation

Answers1. P: WW x ww

F1: WwF2: 3/4 round (W-) to 1/4 wrinkled (ww)

2. P: Ww x wwF1: 1/2 Ww (round) and 1/2 ww (wrinkled)

3. P: GG WW x gg wwF1: Gg WwF2: 9/16 yellow, round (G- W-); 3/16 yellow, wrinkled (G- ww); 3/16 green, round (gg W-); 1/4 green, wrinkled (gg ww)

4. Incomplete dominance5. AB; Codominance6. X-linked recessive7. Sum (this is the “sum rule” or the “addition rule” of probability8. Product (this is the “product rule of probability)

If you found these questions easy

You’re prepared to start this class

If these questions were not easy

You should attend the review session and study review material

Review session: Today, 5 pm, 140 Burrill Hall