What is a mutation?

Genetic Disorders

Make a list of all the genetic disorders you

have heard of – do you know what causes them?

Huntington's disease

• Lesson Learning Outcomes:

Increasing Difficulty

what are the symptoms of Huntington’s disease and how is

it inherited?

List the symptoms of Huntington’s

disease

Interpret genetic diagrams and family trees to

predict the likelihood of

inheriting genetic disorders

Consider the ethical

implications of treatments for

genetic disorders

Huntington’s Disease• We are going to watch a video about Huntington’s disease• While you are watching the video write down any symptoms

of Huntington’s disease.

Value Line

• How guilty is Carol Carr?

Innocent Guilty

Value Line

• How guilty is Carol Carr?

Innocent Guilty

Pass the buck!

• Your table has been given a placemat. Read the question in the middle of the placemat. Each person should take a square and write in their square the answer to the question

Genetic Crosses

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tTtTttTtT

Sickle cell anaemia

• Sickle cell anaemia is a recessive genetic disorder. What are the chances the child of two heterozygous parents will have sickle cell anaemia?

Hypercholesterolemia

• Hypercholesterolemia is a dominant genetic disorder. A homozygous recessive woman and a heterozygous man are going to have children. They want to know what the chances of their child inheriting the condition are.

Achondroplasia

• Achondroplasia is a dominant genetic disorder. What are the chances of two heterozygous parents having a child who inherits the condition?

Genetic Cross snowballing

• Write a problem for someone else (they must have to solve it using a genetic cross diagram).

• Don’t forget to say which characteristic is dominant and which one is recessive

Huntington's disease

• Lesson Learning Outcomes:

Increasing Difficulty

what are the symptoms of Huntington’s disease and how is

it inherited?

List the symptoms of Huntington’s

disease

Interpret genetic diagrams and family trees to

predict the likelihood of

inheriting genetic disorders

Consider the ethical

implications of treatments for

genetic disorders

In a family with a history of Huntington’s why might a child not be allowed the test to see if they have it UNTIL their parents have been

tested?

Why might some people choose to have a test for Huntington’s? What could the ethical implications be after having this test?

Why might some people choose not to have a test for Huntington’s? What could the consequences of this be?

A pregnant woman with a family history of Huntington’s disease is going to get the foetus tested for the disease. What are some of

the ethical implications of this?

Apart from a person’s family, who else might be interested in the results of a genetic test? What might they do with this information?

Some genetic tests can give a “false positive” what do you think this is and what could the implications of this be?

Some genetic tests can give a “false negative” what do you think this is and what could the implications of this be?