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When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces...

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Uncomplicated Type B Dissection When to Intervene ? 1 Pr JP Becquemin Institut Vasculaire Paris Est HPPE Champigny sur Marne France
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Page 1: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Uncomplicated Type B Dissection

● When to Intervene ?

1

Pr JP Becquemin Institut Vasculaire Paris Est

HPPE Champigny sur Marne France

Page 2: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Disclosure

Speaker name: Becquemin

I do not have any potential conflict of interest

Page 3: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Disclosure

Speaker name: Becquemin

I do not have any potential conflict of interest

Page 4: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should
Page 5: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Treatment Options

BMT TEVAR Open surgery

Page 6: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : Mortality / Treatment

Fattori R JACC 2008

10 %

35 %

Page 7: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : Outcomes Endpoints

• Mortality

• Aortic Events

Page 8: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : Mortality BMT

One month 11 %One Year 16 %Five Year 20%

Estrera AL Circulation 2006Clough R EJVS : 2018 Shimamoto T JTCS : 2018

Page 9: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : Outcomes Endpoints

• Mortality

• Aortic Events

Page 10: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : BMT

2008

Page 11: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : BMT 2019

Page 12: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Limits of BMT

Page 13: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

UATBD : BMT CT scan > 8 yrs

Page 14: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should
Page 15: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Flap fibrosis

Page 16: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should
Page 17: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should
Page 18: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

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9165 casesSurvival 1 yr 5 yrBMT 84% 60 %OR 76% 67 %

Tevar 85 % 76 %

Page 19: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

RisksOf TEVAR

Page 20: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

TEVAR for ATBDEUREC Registry (Eggebrecht H Circulation 2008

33/3074 TEVAR (1.1%)Dissection (17 acute, 10 chronic)20/33 urgent Proximal Bar Stent 79%Mortality 42%

Page 21: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

How to select patients for early TEVAR ?

Page 22: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

254 patients FU 6,8 year38 % intervention

Page 23: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should
Page 24: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Recent Advances

• Promote Early False Lumen Thrombosis• Balloon False Lumen Rupture ( Alsac)• Coil embolisation ( Pellenc )• Candy Plug Technique ( Kölbel )

Page 25: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

Take Home Message

• UATBD is a life threatening event• TEVAR improves survival and reduces late aortic

events• TEVAR is justified selectively• False lumen occlusion should be obtained• Optimum delay of for intervention 1-3 months

Page 26: When to Intervene?...• UATBD is a life threatening event • TEVAR improves survival and reduces late aortic events • TEVAR is justified selectively • False lumen occlusion should

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