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Title of Presentation

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EU-ASEAN S&T cooperation to jointly tackle societal challenges

UNCLASSIFIED

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Health in Horizon 2020

Societal Challenge 1: Health, Demographic Change

and

Well-being

Indicative total budget of EUR 7.47 billion - though other societal challenges also

have a relationship to health

Addressing European and global challenges: aging populations, increasing

burdens of disease, pressures on health care sector and systems

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Health in Horizon 2020

Health in 2014/15

Total budget for 2014/15 calls is EUR 1.2 bn

34 topics in Personalising Health and Care, and 16 Co-ordination Activities

PHC includes seven topics; understanding health, improved health information,

prevention, diagnosis, treatment, active and health aging, and integrated and

citizen-centered care

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Health in Horizon 2020

International Cooperation Possibilities in Health in Horizon

2020

1. PHC 4 – 2015: Health promotion and disease prevention: improved inter-sector co-

operation for environment and health based interventions

2. PHC 7-2014: Improving the control of infectious epidemics and foodborne outbreaks

through rapid identification of pathogens

3. PHC 8-2014: Vaccine development for poverty-related infectious diseases- TB

4. PHC 9-2015: Vaccine development for poverty-related infectious diseases- HIV/AIDS

5. HCO 4-2014: Support for international infectious disease preparedness research

6. PHC 14-2015: New Therapies for Rare Diseases

7. HCO 5 – 2014: Global Alliance for Chronic Diseases: prevention and treatment of type 2

diabetes

8. HCO 5 – 2014: Global Alliance for Chronic Diseases: 2015 priority

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Health in Horizon 2020

PHC 4 – 2015: Health promotion and disease prevention: improved

inter-sector cooperation for environment and health based

interventions

• Specific Challenge: Targeting ‘health in all policies’ to foster environments which support

health, well-being and behavioural change.

• Scope: Limited to the integration of environment, climate and health sectors (including air

quality, water and sanitation, chemicals, occupational factors, etc.). Proposals should

develop inter-sector initiatives and/or policy initiatives to promote health or prevent

disease based on known environmental stressors.

• Impact: Evidence on effective interventions, impact on sustainability of healthcare systems.

• Evaluation: Two Stage

• Budget: EUR 4-6 million per proposal, total budget of EUR 18 million

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Health in Horizon 2020

PHC 7 – 2014: Improving the control of infectious epidemics and

foodborne outbreaks through rapid identification of pathogens

Specific challenge: Threat of epidemics caused by existing, new and emerging infectious

diseases (including from antimicrobial resistant pathogens), many of which are zoonoses,

necessitating a “one health” approach

Scope: Sequence based data for pathogens will be generated, stored and analysed in

combination with clinical, microbiological, epidemiological and other data needed for risk

assessment (RA)

Expected Impact: Better containment and mitigation of epidemics by competent authorities

on the basis of a shared information system and global standards for rapid pathogen

identification.

Evaluation: Single Stage + Hearing

Budget: One project with a budget of EUR 15-20 million (incl. 5 from SC2)

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Health in Horizon 2020

PHC 8 – 2014: Vaccine development for poverty-related and

neglected infectious diseases: Tuberculosis

Specific challenge: Many poverty-related and neglected infectious diseases continue to

escape attempts to develop effective vaccines against them.

Scope: Proposals will focus on strengthening the capacity for discovery and early

development of new vaccine candidates for tuberculosis by i) establishing a platform for the

identification of (at least 10) new diverse and novel vaccine candidates for tuberculosis, and

their pre-clinical and early clinical testing, and ii) addressing major bottlenecks in vaccine

development; in particular better ways for early distinction between successful candidates

and those that will eventually fail in late stage clinical trials.

Expected Impact: Reduction in cost associated with late stage vaccine failure, increasing

number of other candidates which can be tested with same resources, links to EDCTP.

Evaluation: Single Stage + Hearing. Deadline 15th April 2014 at 17.00.00 Brussels time.

Budget: One project with a budget of up to EUR 25 million

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Horizon 2020 Health Calls

PHC 9 – 2015: Vaccine development for poverty-related and

neglected infectious diseases – HIV/AIDS

Specific challenge: Many poverty-related and neglected infectious diseases continue to

escape attempts to develop effective vaccines against them

Scope: Proposals will focus on strengthening the capacity for discovery and early

development of new vaccine candidates for tuberculosis by i) establishing a platform for the

identification of (at least 10) new diverse and novel vaccine candidates for tuberculosis, and

their pre-clinical and early clinical testing, and ii) addressing major bottlenecks in vaccine

development; in particular better ways for early distinction between successful candidates

and those that will eventually fail in late stage clinical trials.

Expected Impact: Reduction in cost associated with late stage vaccine failure, increasing

number of other candidates which can be tested with same resources, links to EDCTP.

Evaluation: Single Stage + Hearing.

Budget: Expected to be one project with a budget of EUR 21 million

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Horizon 2020 Calls

HCO 4-2014: Support for international infectious disease

preparedness research

• Specific challenge: Human health threatened by potential epidemics caused by existing, new

and emerging infectious diseases (including from antimicrobial resistant pathogens). In order

to save lives, the research response needs to be quick, flexible, comprehensive and global.

• Scope: The support action should provide organisational support to the implementation of

the global research collaboration for infectious diseases preparedness consortium (GloPID-R),

• Expected Impact: Reinforced international cooperation in funding of research in new and

emerging infectious diseases aiming to ensure a rapid and effective research response in case

of an outbreak.

• Evaluation: Single Stage. Deadline 15th April 2014 at 17.00 Brussels Time.

• Budget: One project of EUR 3 million

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Horizon 2020 Health Calls

PHC 14 – 2015: New therapies for rare diseases

Specific challenge: 6000-8000 rare diseases are lacking therapies despite many diseases

being life-threatening or chronically debilitating.

Scope: Proposals may address one or more of the following: development of new or

improved therapeutic approaches, for repurposing of existing therapies, as well as for

preclinical research, animal model development and good manufacturing practice (GMP)

production. Selected proposals should contribute to the objectives of, and follow the

guidelines and policies of the International Rare Diseases Research Consortium, IRDiRC.

Expected Impact: Proposals should contribute to reaching the IRDiRC objective to deliver

200 new therapies for rare diseases by 2020.

Evaluation: Two stage

Budget: Projects of EUR 4-6 million, with a total budget of EUR 60 million

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Health in Horizon 2020

HCO 5 – 2014: Global Alliance for Chronic Diseases: prevention and

treatment of type 2 diabetes

• Specific challenge: It is currently estimated that 347 million people worldwide suffer from

diabetes with more than 80% from low-and middle-income countries. Halting the rise in

prevalence of diabetes has been identified as one of the 9 WHO non communicable

diseases global voluntary targets to be met by Member States by 2025.

• Scope: Proposals should generate new knowledge on interventions and their

implementation for the prevention and treatment of type 2 diabetes in low and middle

income countries, and in vulnerable populations in high income countries.

• Expected Impact: Reducing health inequalities and inequities, including gender, in the

prevention and treatment of type 2 diabetes in both a local and global context.

• Evaluation: Single stage, deadline 15th April 2014 at 17.00.00 Brussels time

• Budget: Projects of EUR 1 to 3 million, with a total budget of EUR 9 million

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Health in Horizon 2020

HCO 5 – 2014: Global Alliance for Chronic Diseases: prevention and

treatment of type 2 diabetes

• Specific challenge: It is currently estimated that 347 million people worldwide suffer from

diabetes with more than 80% from low-and middle-income countries. Halting the rise in

prevalence of diabetes has been identified as one of the 9 WHO non communicable

diseases global voluntary targets to be met by Member States by 2025.

• Scope: Proposals should generate new knowledge on interventions and their

implementation for the prevention and treatment of type 2 diabetes in low and middle

income countries, and in vulnerable populations in high income countries.

• Expected Impact: Reducing health inequalities and inequities, including gender, in the

prevention and treatment of type 2 diabetes in both a local and global context.

• Evaluation: Single stage, deadline 15th April 2014 at 17.00.00 Brussels time

• Budget: Projects of EUR 1 to 3 million, with a total budget of EUR 9 million

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Health in Horizon 2020

HCO 6 – 2015: Global Alliance for Chronic Diseases: 2015 priority

• Specific challenge: ??

• Scope: ??

• Expected Impact: ??

• Evaluation: Single stage

• Budget: Projects of EUR 1 to 3 million, with a total budget of EUR 12 million

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Health in Horizon 2020

Summary

• Join the TB Vaccine workshop this afternoon from 13.00 in room 405

• Also keeen to explore work on:

– Environment and health based interventions

– HIV vaccines

– Emerging infectious disease

– Antimicrobial resistance

– Non-communicable diseases

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