Xmatrx ELITE

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All-in-One All-at-Once

• All-in-One All-at-Once – IHC, ISH, SS,

Multiplexing and Co-detection

• FISH*

• Fully Automated System from

Microtome to Microscope

Structural Components

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A True Fully Automated Molecular Pathology Workstation

for Laboratories of Today, Tomorrow and Beyond…

Key Features & Benefits

• Fully Automated System from Microtome to

Microscope

• All-in-One All-at-Once – IHC, ISH, SS, Multiplexing

and Co-detection

• FISH*

• Standardized process from baking through final glass

cover slip in 3 simple steps: Load – Click – View slides

• Automates technologies of Today…IHC, ISH, SS,

FISH*, Multiplexing and Co-detection of Nucleic Acid

and Protein Biomarkers

• Designed to automate the technologies of Tomorrow

and Beyond…Gene Expression Profiling, In Situ PCR,

miRNA… and more

• Meets Global regulator requirements and safety

standards

*Optional Software

Key Features & Benefits

• Multi-functional system – IHC, ISH, FISH*, SS,

Multiplexing and Co-detection

• Clean, intense, reliable and reproducible stains with

standardized process for complete automation

from Baking to final cover slip

• Multiple slide processing options – Random,

Continuous and STAT

• Multi-format specimen processing – Frozen and

FFPE sections, Cell preparations, Smears and FNAs

• Optimized protocols and ready-to-use reagents

• Efficient resource utilization

• Predictable, reliable and transparent cost structure

*Optional Software

Efficient, Productive and Profitable System

• High throughput - 100 slides per day (60 slides in

eight hour shift and 40 slide in a overnight run)

• Start overnight run and return to view completed

slides the next morning

• Low cost of ownership

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Compliance

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• Meets Globally accepted safety standards

• ISO 13485:2003 (CMDCAS)

• ISO 9001:2008

• Regulatory Compliant

• USFDA

• IVD - CE

Easy to Use

• Top loading of slides and reagents

• Color coded GUI with real time assay parameters

display

• Real time audio and visual alerts

• Color coded bulk reagent carboys

• Complete information log for every slide

• Short learning curve allows cross-training and rotation of personnel

*Optional Software

Reproducible, Reliable and Consistent Results

• User defined customized protocols – Clean, intense

stain with Ready-to-use reagents

• Factory protocols for ease of use

• User defined protocols for convenience

• Liquid level sensor for accurate dispensing and real

time reagent tracking – avoid false results

*Optional Software

On-Board Dehydration and

Final Coverslip

Reaction Micro-chamber

and Micro-fluidics

eXACT™ Temperature

Control on Every Slide

Liquid Level Sensor &

Reagent Dispensing System LIS Enabled

RFID and Barcode

Enabled

Enabling Technologies

Reaction Micro-Chamber with Micro-fluidics

• Reaction micro-chamber: 25 µL to 100 µL

• Reduced reagent consumption up to 75%

• Even distribution of reagents for uniform staining

without edge effect

• Overnight incubation/hybridization without drying

of specimen

eXACTTM Temperature Control on Every Slide

• 40 independent thermocyclable (PCR) work

stations

• No cross talk - High precision active heating and

cooling maintains accurate temperature on each

slide at all times

• Temperature uniformity + 2°C

• Temperature range from Ambient to 105°C for

robust antigen retrieval

• Thermocycling - Ambient 95°C< 2 min

RFID and Barcode Enabled Technology

• RFID tagged reagent vials – Accurate and precise

real time reagent usage tracking irrespective of

Xmatrx system

• Barcoded slides – eliminates human errors, correct

protocols on each slide delivering accurate results

Liquid Level Sensor and Reagent Dispensing System

• Redundant automated process to eliminate human

errors

• Accurate dispensing of micro-reagent volumes

• Error free reagent dispensing – delivers optimum

stains, eliminates false negatives

• Disposable pipette tips allows multiple

technologies on the same platform without cross

contamination

On-board Dehydration and Final Coverslip

• Dehydration

• Clearing

• Permanent mounting with glass cover slip

Intuitive Software System - LIS Enabled

• Easy to use user friendly GUI

• Multiple standardized and custom reporting

capabilities

• Usage tracking

• Inventory management

• Regulatory compliant

• LIS Enabled data tracking and management*

*Optional

Xmatrx ELITE – A Unique Value Proposition

• All-in-One All-at-Once

• Multiple technologies on a single platform - IHC,

ISH, SS, Multiplexing and Co-detection

• FISH*

• Fully automated system with standardized process

from baking through final glass cover slip in

3 simple steps: Load – Click – View slides

• Reduced reagent consumption by up to 75%

through the use of Reaction Micro-chamber with

Micro-fluidics

• Walkaway Automation through RFID and Barcode

enabled platform

• Disposable pipette tips allow multiple technologies

on the same platform

*Optional Software

Value Proposition - Pathologist

• All-in-One All-at-Once

• Multiple technologies on a single platform -

IHC, ISH, SS, Multiplexing and Co-detection

• FISH*

• Clean, intense, consistent and reproducible results

• High throughput system - 100 slides per day, 60

slides in eight hour shift and 40 slides in a

overnight run

• Disposable pipette tips allow multiple technologies

on the same platform

• Wide variety of antibodies, different clones and

compatible reagents provide complete portfolio

for the system

• Multiple technologies on the same system

*Optional Software

Value Proposition - Management

• Fully automated All-in-One All-at-Once system

• Low cost of ownership

• Eliminate requirement to purchase multiple

instruments for different technologies

• High throughput, efficient, productive and

profitable system

• Optimize resource utilization and cross training

• Predictable, reliable and transparent cost structure

• Eco-friendly and Cost savings – up to 75% reduced

reagent consumption and waste generation

through cutting edge technologies

• LIS enabled intuitive software system for accurate

usage tracking, inventory management and

generating regulatory compliant reports

*Optional Software

TIME

COST

QUALITY

Value Proposition - Lab Personnel (1/2)

• All-in-One All-at-Once

• Multiple technologies on a single platform - IHC,

ISH, SS, Multiplexing and Co-detection

• FISH*

• Fully automated system with standardized process

from Baking through final glass cover slip in 3

simple steps: Load – Click – View slides

• High throughput - 100 slides per day, 60 slides in

eight hour shift and 40 slide in a overnight run

• Advanced Enabling Technologies - RFID, Barcode,

Liquid Level Sensor, eXACT Temperature Control

and Reaction Micro-chamber with Micro-fluidics

• On-board dehydration, clearing and permanent

mounting with glass cover slip

*Optional Software

Value Proposition - Lab Personnel (2/2)

• Multiple slide processing options – Random,

Continuous and STAT

• Multi-format specimen processing – Frozen and

FFPE sections, Cell preparations, Smears and FNAs

• Easy to use user friendly GUI

• Factory protocols for ease of use

• User defined customized protocols for

convenience

• Real time audio and visual alerts

• Short learning curve allows cross-training and

rotation of personnel

• Multiple standardized and custom reporting

capabilities for Usage tracking, Inventory

management and Regulatory compliance

*Optional Software

Applications

IHC

Special Stains

ISH

Multiplexing IHC/ISH

Multiplex Stains

FISH

Thank YouPlease visit www.biogenex.com for more details on our product portfolio

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