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Tech Transfer: from Academy to Industry, Business Models and CasesAriela Markel, VP Business Development, Healthcare
May 2011
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A Heritage of Excellence
5 Campuses5 affiliated hospitals
3,500 Research projects >100 Research
centersOver 400 Researchers
in applied sciences
1,600 Post-Graduate students in biotechnology
1,000 researchers (staff members)
23,000 students
30% of all Israeli academic scientific research
43% of Israel’s biotechnology
research>1/3 of PhD
students in Israel
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About Yissum
Founded in 1964
28 experts in the fields of:LicensingResearch CollaborationsPatentsLegalFinance & admin
Headed by Yaacov Michlin
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Areas of Expertise
Pharmacology and Medicine
Brain Research
Nanoscience and Advanced Materials
Agriculture
Cleantech
Engineering and Computer Science
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Yissum’s Role
• Identification of technologies with commercial potential.• Analysis of commercialization opportunities: market size, market players,
competitive environment• Protection of the technology (IP) by patents or other tools and adequate
contracts (IIA)• Research collaborations, joint ventures, services (analysis, feasibility
studies, models)• Licensing of patents• Company creation (spin offs)• Participation in national projects (Magnet, others)• Internal funding for selected applied sciences projects (Baby Seed fund,
etc), including joint funding.
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Inventions providers: Our Researchers!
Faculty of Humanities
Faculty of Social Sciences
Faculty of Science
School of Business Administration
Faculty of Law and Institute of Criminology
School of Dental Medicine
Faculty of Medicine
Faculty of Agriculture
School of Computer Science and Engineering
School of Pharmacy
Interdisciplinary Centers
Truman Institute for Advancement of Peace
Institute for Advanced Studies
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The Challenge
Product-based
Business-oriented
Mission/project focused
Confidentiality essential
Timeframes & milestones
Economic role
Knowledge-based
Curiosity-driven
Broad scope
Publications
No time limits
Educational role
Industry Academia
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Intellectual Property
2010 Snapshot120 new inventions 155 new patent applications63 new patents granted
Intellectual Property at HUYissum owns all IP developed at HUResearchers receive 40-60% of revenues
Life Science & Biotechnology
56%
Materials16%
Agriculture, Food &
Nutrition, Cleantech
13%
Applied physics
6%
Computer Science &
Engeneering9%
A variety of new
inventions
Over the years• 7,077 patents• 2,023 inventions• 530 licenses• 72 spin-offs
Yissum’s Business Models
According to:
Technology’s characteristics: stage of development, project complexity, IP strength
Market characteristics: competitive environment, key players, investment required
We develop different Business Models:
Collaborative Research and Right of First Offer
Research and Licensing
Spin-off (start-ups, incubator companies)
Other types of cooperation, including consortia participation
Yissum’s Funding Initiatives 2008-2010
“Baby Seed”
$1m in 2010 dedicated to seed promising technologies.
Helps promising technologies cross the Valley of death
Up to $ 200 K per project in the form of a “loan”
Successful projects return the loan, for non successful becomes a grant
Major Types of Technology Transfer Agreements
Confidential Disclosure Agreement (CDA)
One-Way
Mutual
Material Transfer Agreement (MTA)
Academic
Industry
Consulting Agreement
Stand Alone
Part of Research or LA
Laboratory Services Agreement
Sponsored Research Agreement
Memorandum of Understanding
Research & License Agreement
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Global Reach
The Research And License Agreement
The License
Exclusive or non-exclusive
Exclusive limited to Field is really form of non-exclusive license
Territory covered by license
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The Research And License Agreement (2)
Consideration
Up-front license fee
Royalties
Sublicense Fees
Development/Other Milestone
Equity
Exit Fee
Minimum Royalties/License Maintenance Fee
Anti-shelving mechanism
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Business Flexibility– IP Issues
• Yissum is responsible for making all contractual and financial arrangements and aims to prepare agreements timely and with maximum flexibility to meet industry needs.
In typical research collaborations including licenses that include sponsored research, the research results belong to the Sponsor and the IP generated by HU researchers in the course of providing the research is exclusively licensed to the Sponsor for commercial use in its field of activity.
Yissum’s policy is to always find the way to allow industry to collaborate with HU researchers, through finding the right path of IP ownership/licensing for each project based on the subject of the research and the related Yissum background technology.