Slide 110/20/08
Mucegaiul strugurilor/PLAVI
Clasa chimica noua– benzamida
Descoperita de Rohm si Haas in 1992 si patentata in 1993
Vanduta la Dow AgroSciences (DAS)
DAS a obtinut prima inegistrare in 2001
Commercializat in 2002
Molecula
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Tine sub control bolile cheie ale cartofului, strugurelui, tomatelor si leguminoaselor:
Putregaiul tarziu
Putregaiul timpuriu
Mucegaiul
Tine sub control si alte boli in combinatie cu alte fungicide cu alt mod de actiune precum mancozebul.
Optiuni/ Ready Mix
Potenteaza eficienta fungicidelor asociate.
Mancozeb
Zoxium
Zox+Mz (theory)
Zox+Mz (practice)
Study of synergy according to Colby: S = x+y-(xy/100) x = % efficacy with product A, y =% efficacy with product B
31
49
65
84
Synergie
Resultat de l'étude de synergie par la formule de Colby:
% Efficacy against potato late blight
Mancozeb
31
Zoxium
49
Zox+Mz (theory)
Zox+Mz (practice)
Study of synergy according to Colby: S = x+y-(xy/100) x = % efficacy with product A, y =% efficacy with product B
Resist.Less.
A la fin du traitement
7 jours + tard
14 jours + tard
Dans l'épiderme (immobile)
Devenir du Zoxium dans la feuille de pomme de terre
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Gavel (U.S. si Canada) Electis (EU), Unikat Pro (EU), Aderio(France)
1:8 – 75 DG Zoxamida + Mancozeb(8.3% + 66.7%)
Unikat (EU), Electis Pro(EU), Roxam(EU)
1:11.2 – 76.2 DG Zoxamida+ Mancozeb(6.25%+70%)
Stimo(SA)
Harpon (Mexico, Brazil)
Zoxium (South Africa)
Profiul produselor cu zoxamida
Actiuneaza intr-un singur loc
Activitate protectanta
Translocatie minima
Zoxium acts within Mitosis / nuclear division by binding irreversibly to beta-tubulin (a protein essential for nuclear division) through covalent attachment.
Zoxamide disrupts the formation of the microtubule and inhibits nuclear division
(a unique m.o.a. for Oomycete fungicides)
FRAC group 22
Zoxamide MOA
*
Oprierea cresterii hifelor
epifluorescence microscopy taken 6 hours post application of Zoxamide
Mecanismul actiunii zoxamidei
*
C: Mitocondrie/Respiratie
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ZOXIUM®
Inovatie
Mancozebul previne germinarea sporilor pe suprafata frunzei
Mancozebul este inregistrat in peste 70 de tari la nivel mondial
peste 70 (20+ EU) la culturi diferite
Peste 400 de specii de fungusi
Activ de 40 de ani fara efecte adverse majore raportate
Zoxamida actioneaza dupa germinarea sporilor
la formarea urmatorului nucleu, impiedicand elongarea hilului
Aceasta actiune are loc pe masura ce tubul fungusului creste de-a lungul suprafetei frunzei sau prin cuticula ceroasa pana in interiorul frunzei
Zoxamida opreste dezvoltagrea sporilor in sporangie
inainte ca acestia sa fie eliberati
Actioneaza inainte sporicizilor traditionali(inainte ca zoosporii sa fie motili)
*
*
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Zoxamida + Mancozeb (1:8) Inregistrata in 20 de tari din UE (30 in EUMENA)
Zoxamida + Mancozeb (1:11.2) inregistrata in 3 tari
Includerea in Anexa I: Aprilie 2004
Inscrierea in Anexa III: 2 formulations (1:8 si 1:11.2)
Numar de cod GF1045 (sau GF1572) si GF1057
Inscrisa in majoritatea statelor in iulie 2008
(acum in curs de evaloare)
Grecia si UK sunt RMS regionale
Formulari pe baza de cupru au fost inscrise in 2011
Zoxamida: Situatia in UE
Ambele substante active tin sub control mucegaiul si putregaiul
Mancozeb controleaza putregaiul timpuriu si alte boli.
Combinatia are un efect de sinergism de potentare.
Profilul tehnic de uz
Cucurbit
Strugure
Mucegaiul
31 49 65 84 0102030405060708090% Efficacy against potato late blight
Study of synergy according to Colby: S = x+y-(xy/100) x = % efficacy with product A, y =% efficacy with product B
MancozebZoxiumZox+Mz (theory)Zox+Mz (practice)