Date post: | 02-Mar-2023 |
Category: |
Documents |
Upload: | independent |
View: | 0 times |
Download: | 0 times |
INTRODUCTION • Also known as ‘Green Monkey Fever’.
• First Recognized in Democratic Republic of Congo (formerly Zaire) in 1976.
• It got it’s name from the Ebola River in Congo.
• An RNA virus from the Filoviridae family.
• It’s natural reservoir is unknown but believed to be in Monkeys, Gorillas, and Fruit Bats.
• The latest outbreak was in March 2014 in Guinea and Liberia.
THE TYPES
There are 5 identified subtypes:
-Bundibuygo Ebolavirus (BDBV)
-Zaire Ebolavirus (EBDV)
-Sudan Ebolavirus (SUDV)
-Tai Forest Ebolavirus (TAFV)
-Reston Ebolavirus (RESTV)
The first three are fatal, predominant in Africa.
TAFV & RESTV are predominant in Asia and Philippines.
HOW IS IT SPREAD? • It presents as a hemorrhagic fever with a fatality rate of
90%
• Contact with infected animals
• Person to person contact
• Sporadic outbreaks
• There is no “carrier” state, that is a person harbouring the disease without showing signs of infection
TRANSMISSION
• Direct contact with blood or secretion of an infected person.
• Ingestion of infected animal—Bushmeat.
• Via fomites: clothing, utensils, toys, etc.
• Nosocomial transmission—within healthcare setting and in morgues.
• Airborne transmission (aerosols)– This mode is still being queried in humans.
SYMPTOMS Incubation period of 2-21days with abrupt onset
-Fever
-Headache
-Joint & Muscle pain
-Sore throat
-Severe fatigue
-Gastrointestinal symptoms
-Rash
-Red eyes
-Bleeding (both internal & external)
CLINICAL DIAGNOSIS
• First rule out other infections that present with “Flu-like” symptoms.
• Early symptoms are usually non-specific hence a person who presents with a raid of symptoms, should be suspected for the virus.
-Isolate such person (Quarantine)
-Notify local and state health departments
LABORATORY TESTS
• ELISA (Enzyme linked immunosorbent assay)
• RT-PCR (Reverse transcriptase-polymerase)
• Virus isolation by cell culture
• Serum neutralization test
• IgM and IgG for the viral antibodies
TREATMENT
No curative treatments or vaccines available, therefore, supportive therapy is best as soon as detected:
-Balance fluids & electrolytes
-Oxygen therapy
-Maintain blood pressure
-Use of antibiotics for complications
-Use of anticoagulants (prevents blood clots where necessary)
PREVENTION
• Proper hand washing/sanitization.
• Health workers should use proper protective equipments—masks, gloves, etc.
• Extreme care to be applied in funeral homes.
• Minimal exposure to wildlife.
• Avoid travel/tours to high incidence areas.