Download - Aaron A. Best, Ph.D. · Aaron A. Best, Ph.D. Harrison C. and Mary L. Visscher Professor of Genetics Department of Biology, Hope College 35 East 12th Street, Holland, MI49423 (616)

AaronA.Best,Ph.D.HarrisonC.andMaryL.VisscherProfessorofGenetics

DepartmentofBiology,HopeCollege35East12thStreet,Holland,MI49423

(616)395-7376,[email protected],@aaron_best

Education

Post-doctoral.MicrobialEvolution.DepartmentofMicrobiology,UniversityofIllinoisatUrbana-Champaign.Advisor:CarlR.Woese,Ph.D. 2002-2004DoctorofPhilosophy.Microbiology.DepartmentofMicrobiology,UniversityofIllinoisatUrbana-Champaign.Thesis:EvolutionoftranscriptioninArchaeaandtheearly-divergingeukaryote,GiardialambliaAdvisor:GaryJ.Olsen,Ph.D. 1996-2001MastersofScience.Microbiology.DepartmentofMicrobiology,UniversityofIllinoisatUrbana-Champaign.Advisor:GaryJ.Olsen,Ph.D. 1996-1999BachelorofArts.Biology.DepartmentofBiology,WilliamJewellCollege,Liberty,MO.Thesis:Assessingphylogeneticrelationshipsamongredalgaeusing18SribosomalDNAThesisAdvisor:PaulW.Gabrielson,Ph.D. 1992-1996

AcademicAppointmentsHarrisonC.andMaryL.VisscherProfessorofGenetics.DepartmentofBiology,HopeCollege,Holland,MI. 2015-presentHarrisonC.andMaryL.VisscherAssociateProfessorofGenetics.DepartmentofBiology,HopeCollege,Holland,MI. 2012-2015GuestResearchFaculty.ArgonneNationalLaboratory,Argonne,IL. 2011VisitingResearchScientist.TheSanfordBurnhamMedicalResearch 2010-2011Institute,LaJolla,CA.AssociateProfessorofBiology.DepartmentofBiology,HopeCollege, 2010-2015Holland,MI.VisitingResearchScientist.TheBurnhamInstituteforBiomedical 2008Research,LaJolla,CA.GuestResearchFaculty.ArgonneNationalLaboratory,Argonne,IL. 2007AssistantProfessorofBiology.DepartmentofBiology,HopeCollege, 2004-2010Holland,MI.

February2018 AaronA.Best,Ph.D. 2

HonorsandAwardsMacatawaAreaCoordinatingCouncil“StakeholderoftheYear”Award 2017InauguralHolderoftheHarrisonC.andMaryL.VisscherEndowedProfessorshipinGenetics,HopeCollege 2012-2022VisitingResearchScientist,TheSanfordBurnhamMedicalResearchInstitute,LaJolla,CA 2010-2011ArgonneNationalLaboratoryGuestFacultyResearchProgram 2011VisitingResearchScientist,TheBurnhamInstituteforBiomedicalResearch,LaJolla,CA 2008ArgonneNationalLaboratoryGuestFacultyResearchProgram 2007TowsleyResearchScholar,HopeCollege 2007-2010ProjectKaleidoscope(PKAL)F21Program 2006 OutstandingTeachinginMicrobiology,UniversityofIllinois 1998-1999UniversityofIllinoisListofTeachersRankedasExcellent(6semesters) 1996-1999FullscholarshiptoattendWorkshoponMolecularEvolution,MarineBiologicalLaboratory,WoodsHoleMA 1999OutstandingSeniorBiologyMajor,WilliamJewellCollege 1996CambridgeHonorsScholar 1994-1995CouncilonUndergraduateResearchSummerOpportunitiesforResearchCURSORFellowshipAward 1994PresidentialScholarship,WilliamJewellCollege 1992-1996Dean’sList,WilliamJewellCollege 1992,1995AlphaLambdaDeltaHonorsSociety 1992

ResearchInterests

Microbialgenomics–comparativegenomics,genome-scalemetabolicmodeling,transcriptionalregulatorynetworkmodeling,identificationofmissinggenefunction,genomesequencing,andmicrobialecologyofdifferentecosystemsMicrobialevolution–evolutionofmetabolicandtranscriptionalnetworksinmicrobes,comparativeanalysesoftranscriptionsystemsineukaryotes,mechanismsoftranscriptioninGiardialambliaApproachataPrimarilyUndergraduateInstitution

Convergence–Myresearchinterestsarebest-approachedusingtechniquesrangingfromtargetedbiochemicalandmolecularstudiestomodelingandinterpretationoflarge-scaledatasetsbeingproducedinthebiologicalsciencestoday.Thetechniquesandquestionssitattheinterfaceamongmultipledisciplines.Thus,myworkislargelycollaborativetobringmulti-disciplinaryperspectivesandskillstothestudiesathand.WorkinginthecontextofaprimarilyundergraduateinstitutioninaBiologydepartmentprovidesrichopportunitiesforinvestigationofproblemsonmultiplescalesofbiologyandallowsforfruitfulcollaborationwithlargeresearchinstitutions.


IntegrationofResearchintoCourses–Course-basedResearchExperiences(CREs)arebeneficialtoboththeresearchprogramandtothestudents.CREsoftenproduceusefulpreliminarydataandproviderecruitingopportunitiesforstudentstrainedintheprojectarea.CREsallowmorestudentstolearnsciencebyactuallydoingsciencethanIamabletomentordirectlyinmylaboratory.ManyofthemajorareasofmyresearchinterestshavebeenimplementedasCREsincoursesthatIteach.

ResearchSupport–Extramural(boldeddatesindicateongoing)

(Averagelevelofannualizedexternalsupportsince2012is$790,791;currentannualizedlevelofexternalsupportis$1,631,751)

NationalScienceFoundation,AwardNumberMCB-1716285“CollaborativeResearch:RUI:Investigatingmicrobialmetabolicandregulatorydiversitybymodelinggeneactivitystatesinferredfromtranscriptomedata”$488,522 Sep2017–PI:BestAandDeJonghM Aug2020NationalScienceFoundation,AwardNumberMCB-1616737“RUI:DynamicsofGenomicMosaicisminNon-HostAssociatedEscherichiaPopulations”$775,316 Aug2016–PI:BestA Jul2019SawyerProducts“GlobalSurveyofMicrobialPopulationsandChemicalContaminantsinWaterSources”$314,000 Jul2016–PI:BestA,PetersonJ,PikaartMandPeasleeG Dec2017ArnoldandMableBeckmanFoundation“BeckmanScholarsProgram”$104,000 May2015–Co-PI:JohnsonJandBestA May2018HerbertH.andGraceA.DowFoundation“MeetingthePersistentChallenges:Recruiting,Retaining,and GraduatingMichiganSTEMStudents”$3,000,000 Dec2014–Co-PI:MaderC,PeasleeGandBestA Nov2017NationalScienceFoundation,AwardNumberMCB-1330734“CollaborativeResearch:RUI:DevelopingIntegratedMetabolicRegulatoryModels(iMRMs)fortheInvestigationofMetabolicandRegulatoryDiversityofSequencedMicrobes”$399,511 Oct2013–PI:BestAandDeJonghM Sep2017OutdoorDiscoveryCenterMacatawaGreenway“PhysiologicalandGenomicCharacteristicsofEscherichiacoliIsolatesfromtheMacatwaWatershed”$12,000 Sep2013–


PI:BestAandPeasleeG Aug2014GreatLakesCollegeAssociation,NewDirectionsInitiative“MicrobialInteractionsinDormantSeeds:TrainingaCollaborativeTeamtoIntegratetheMicrobiomewithPlantPopulationEcology”$10,000 Aug2012–Co-PI:MurrayKG,BestA,BrownKandBultmanTL Aug2013AmericanSocietyforMicrobiology,UndergraduateResearchFellowshipProgram"Genome-wideanalysisoftranscriptionfactorbindinginGiardialamblia"$1,000(AcceptedTravelAwardPortionofFunding;DeclinedProjectFunding) Jun2013–Mentor/PI:ValesanoA(undergraduate)andBestA May2014NationalScienceFoundation,AwardNumberDBI-1229585“MRI:AcquisitionofaBenchtopNextGenerationSequencingPlatformtoEnhanceUndergraduateResearchandEducationatHopeCollege”$171,877 Sep2012–PI:BestAandLiJ Aug2015DepartmentofEnergy,SubcontractNumber2F-30041“KBase:AnIntegratedKnowledgebaseforPredictiveBiologyandEnvironmentalResearch”$380,000 Oct2011–PI:BestA,DeJonghMandTintleN Sep2016NationalScienceFoundation,AwardNumberABI-0850546"ExtendingtheRASTServertoSupportReconstructionandModelingofCellularNetworks"$1,267,183 Sep2009–Co-PI:DeJonghM,BestA,TintleN,RodionovDandOverbeekR Aug2012NationalScienceFoundation,AwardNumberMCB-0745100"RUI:AutomatedMetabolicReconstructionforAllSequencedMicrobialGenomes"$235,022 Aug2008–Co-PI:DeJonghMandBestA Jul2012HowardHughesMedicalInstitute,NationalGenomicsResearchInitiative“PhageGenomicsResearchCourse”~$36,000(equipmentandsupplies) Jan2008–Co-Director:BestAandStukeyJ May2011NationalScienceFoundation,AwardNumberDBI-0821832"MRI:AcquisitionofAutomatedGeneticAnalyzerforInterdisciplinaryResearch,TeachingandTraininginMolecularPhylogenetics,BiologyandBioinformaticsinanUndergraduateCollege"$117,080 Sep2008–


Co-PI:BestA,EvansTandMcDonoughV Aug2009AmericanSocietyforMicrobiology,UndergraduateResearchFellowshipProgram"ValidationofMissingGeneFunctionsintheRhamnoseMetabolicPathwayofBacillus,StreptomycesandSalmonella"$3,000 Jun2007Mentor/PI:StantonK(undergraduate)andBestA May2008

ResearchSupport–Intramural(boldeddatesindicateongoing)HopeCollegeHowardHughesMedicalInstitute,2014Course-basedResearch(CRE)DevelopmentAwardCourseTitle“ProgrammingFoundationswithApplicationModules”$20,000 May2015–Co-PI:McFallR,BandstraB,BestAandKruegerB May2017HopeCollegeHowardHughesMedicalInstitute,2014Course-basedResearch(CRE)DevelopmentAwardCourseTitle“BIOL301:GeneralMicrobiologyLaboratory”$10,000 May2014–PI:BestA Dec2015HopeCollegeHowardHughesMedicalInstitute,2010HughesResearchScholarAward“ScreeningofNaturalPlantExtractsforAnti-ParasiticActivity”$5,900 Jun2010–Mentor/PI:JansenE(undergraduate)andBestA Aug2010HopeCollegeHowardHughesMedicalInstitute,FacultyDevelopmentGrantforCollaborativeResearch"ScreeningofNaturalSeedExtractsfromTropicalandDomesticPlantsforAnti-parasiticActivity"$12,500 Jun2009–Co-PI:BestA,DestaDandMurrayKG Jun2010HopeCollege,TowselyResearchScholarAward“ASystemsBiologyApproachtoUnraveltheComplexitiesofMicrobialLife”$16,000+Sabbatical Jun2007–PI:BestA Aug2010HopeCollegeHowardHughesMedicalInstitute,InterdisciplinaryFullCourseDevelopmentAward"PhageGenomicsResearch"$10,000 May2008–Co-PI:BestAandStukeyJ Jun2009HopeCollegeHowardHughesMedicalInstitute,FacultyDevelopmentGrantforInterdisciplinaryResearch "NucleosomeDynamicsinGiardialamblia:APreliminarySearchforHistoneModificationsinaPrimitiveEukaryote"$10,000 Jun2008–


Co-PI:BestAandPikaartM Dec2008HopeCollegeHowardHughesMedicalInstitute,InterdisciplinaryCourseDevelopmentAward"MethodsinModelingComplexSystems"$5,000 Jan2007–Co-PI:BestAandKruegerB May2007HopeCollegeHowardHughesMedicalInstitute,FacultyDevelopmentGrantforInterdisciplinaryResearch"EvaluationandImplementationofStructuralEquationModelingasaStatisticalMethodforRefiningTheoreticalGenome-ScaleModelswithExperimentalData"$10,000 Jun2006–Co-PI:BestA,DeJonghMandTintleN Dec2006HopeCollegeHowardHughesMedicalInstitute,InterdisciplinaryCaseStudyDevelopmentAward"What'sintheCup?"$2,500 Mar2006–Co-PI:BestAandBartonA. Aug2006HopeCollege,SummerFacultyDevelopmentGrant $2,500 Jun2006– BestA Aug2006HopeCollegeHowardHughesMedicalInstitute,FacultyDevelopmentGrantforInterdisciplinaryResearch"DevelopmentofaSoftwareEnvironmentforComparativeGenomeAnalysisandAnnotation"$10,000 Jun2005–Co-PI:BestAandDeJonghM Dec2005HopeCollege,SummerFacultyDevelopmentGrant $2,500 Jun2005– BestA Aug2005

Publications

15peerreviewedpublicationssince2012,including10withover100undergraduateco-authors.Namesofundergraduateco-authorsareindicatedbyanasterisk.GoogleScholar:http://scholar.google.com/citations?hl=en&user=vX6KclIAAAAJISIWebofScience:5245citationssince2013;6933citationstotal;h-index=16

ResearchPapers1. ArkinAP,StevensRL,CottinghamRW,MaslovS,HenryCS,etal.(2017)TheDOE

SystemsBiologyKnowledgebase(KBase).NatureBiotech.InPress.2. HanauerDI,GrahamMJ,SEA-PHAGES,BetancurL,BobrownickiA,CresawnSG,

GarlenaRA,Jacobs-SeraD,KaufmannN,PopeWH,RussellDA,JacobsWR,SivanathanV,AsaiDJ,HatfullGF.(2017)AnInclusiveResearch-Education


Community(iREC):ImpactoftheSEA-PHAGESprogramonresearchoutcomesandstudentlearning.Proc.Natl.Acad.Sci.114:13531-13536.http://www.pnas.org/content/114/51/13531.full

3. BowermanN*,TintleN,DeJonghMandBestAA.(2017)IdentificationandAnalysisofBacterialGenomicMetabolicSignatures.Biocomputing2017.WorldScientific.pp.3-14.http://dx.doi.org/10.1142/9789813207813_0002

4. BestAA,PorterAL*,FraleySMandFraleyGS.(2017)CharacterizationofGutMicrobiomeDynamicsinDevelopingPekinDucksandImpactofManagementSystem.Front.Microbiol.7:2125.http://journal.frontiersin.org/article/10.3389/fmicb.2016.02125/full

5. FariaJP,DavisJJ,EdirisingheJN,TaylorRC,WeisenhornP,OlsonRD,StevensRL,RochaM,RochaI,BestAA,DeJonghM,TintleNL,ParrelloB,OverbeekRandHenryCS.(2016)ComputingandApplyingAtomicRegulonstoUnderstandGeneExpressionandRegulation.Front.Microbiol.7:1819.https://www.frontiersin.org/articles/10.3389/fmicb.2016.01819/full

6. DisselkoenC,GrecoB*,CookK*,KochK*,LereboursR*,VissC*,CapeJ*,HeldE*,AshenafiY*,FischerK*,AcostaA*,CunninghamM*,BestAA,DeJonghMandTintleN.(2016)ABayesianFrameworkfortheClassificationofMicrobialGeneActivityStates.Front.Microbiol.7:1191.http://journal.frontiersin.org/Article/10.3389/fmicb.2016.01191/abstract

7. Schenk,A*,Porter,AL*,Alenciks,E*,Frazier,K*,Best,AA,Fraley,S.M.,etal.(2016).Increasedwatercontaminationandgrow-outPekinduckmortalitywhenraisedwithwatertroughscomparedtopin-meteredwaterlinesusingaUnitedStatesmanagementsystem.Poult.Sci.95(4):736-748.http://ps.oxfordjournals.org/content/95/4/736.full

8. PowersS*,DeJonghM,BestAAandTintleNL.(2015)Cautionsaboutthereliabilityofpairwisegenecorrelationsbasedonexpressiondata.Front.Microbiol.6:650http://dx.doi.org/10.3389/fmicb.2015.00650

9. PopeWH,BowmanCA,RussellDA,Jacobs-SeraD,AsaiDJ,CresawnSG,JacobsWR,HendrixRW,LawrenceJG,HatfullGF,ScienceEducationAlliancePhageHuntersAdvancingGenomicsandEvolutionaryScience*,PhageHuntersIntegratingResearchandEducation,andMycobacterialGeneticsCourse.(2015)Wholegenomecomparisonofalargecollectionofmycobacteriophagesrevealsacontinuumofphagegeneticdiversity.eLife.4:e06416.*Includes42HopeCollegeUndergraduateStudentAuthors.http://dx.doi.org/10.7554/eLife.06416

10. RodionovaIA,LiX,ThielV,StolyarS,StantonK*,FredricksonJF,BryantDA,OstermanAL,BestAAandRodionovDA.(2013)ComparativegenomicsandfunctionalanalysisofrhamnosecatabolicpathwaysandregulonsinBacteria.Front.Microbiol.4:407.(correspondingauthor)http://www.frontiersin.org/Journal/10.3389/fmicb.2013.00407/full

11. PopeWH,Jacobs-SeraD,BestAA,BroussardGW,ConnerlyPL,DedrickRM,KremerTA,OffnerS,OgiefoAH,PizzornoMC,RockenbachK,RussellDA,StoweEL,StukeyJ,ThibaultSA,ConwayJF,HendrixRWandHatfullGF.(2013)ClusterJMycobacteriophages:IntronSplicinginCapsidandTailGenes.PLoSONE.8(7):e69273


http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0069273

12. RavcheevDA,BestAA,SernovaNV,KazanovMD,NovichkovPS,RodionovDA.(2013)Genomicreconstructionoftranscriptionalregulatorynetworksinlacticacidbacteria.BMCGenomics.14:94.http://www.biomedcentral.com/1471-2164/14/94

13. TintleNL,SitarikA*,BoeremaB*,YoungK*,BestAAandDeJonghM.(2012)Evaluatingthequalityofgenesetsusedintheanalysisofbacterialgeneexpressiondata.BMCBioinform.13:469.http://www.biomedcentral.com/1471-2105/13/193

14. RodionovaIA,YangC,LiX,KurnasovOV,BestAA,OstermanAL,RodionovDA.(2012)DiversityandVersatilityoftheThermotogamaritimaSugarKinome.J.Bacteriol.194:5552-5563.http://jb.asm.org/content/194/20/5552

15. RavcheevDA,BestAA,TintleN,DeJonghM,OstermanAL,NovichkovPSandRodionovDA.(2011)InferenceoftheTranscriptionalRegulatoryNetworkinStaphylococcusaureusbyIntegrationofExperimentalandGenomics-BasedEvidence.J.Bacteriol.193:3228-3240.http://jb.asm.org/cgi/content/full/193/13/3228

16. PopeWH,Jacobs-SeraD,RussellDA,PeeblesCL,Al-AtracheZ,etal*.(2011)ExpandingtheDiversityofMycobacteriophages:InsightsintoGenomeArchitectureandEvolution.PLoSONE6(1):e16329.doi:10.1371/journal.pone.0016329.*Includes18UndergraduateStudentAuthorshttp://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0016329

17. DestaD,SjoholmR*,LeeL,LeeM,DittenhagerK,CancheS*,BabuB,ChavdaS,DewarC,YanowS,BestAAandLeeM.(2011)SynthesisandAntiprotozoalActivityof1,2,3,4-Tetrahydro-2-thioxopyrimidineAnalogsofCombretestatinA-4.Med.Chem.Res.20:364-369.http://www.springerlink.com/content/53r936311433600v/

18. HenryCS,DeJonghM,BestAA,FrybargerP*,LinsayB*andStevensRL.(2010)High-throughputgeneration,optimizationandanalysisofgenome-scalemetabolicmodels.NatureBiotech.28:977-982.http://www.nature.com/nbt/journal/v28/n9/full/nbt.1672.html

19. TintleNL,BestAA,DeJonghM,VanBruggenD*,HeffronF,PorwollikSandTaylorRC.(2008)Genesetanalysesforinterpretationofmicroarrayexperimentsonprokaryoticorganisms.BMCBioinform.9:469.http://www.biomedcentral.com/1471-2105/9/469

20. AzizRK,BartelsD,BestAA,DeJonghM,DiszT,EdwardsRA,FormsmaK*,GerdesS,GlassEM,KubalM,MeyerF,OlsenGJ,OlsonR,OstermanAL,OverbeekRA,McNeilLK,PaarmannD,PaczianT,ParrelloB,PuschGD,ReichC,StevensR,VassievaO,VonsteinV,WilkeAandZagnitkoO.(2008)TheRASTServer:RapidAnnotationsusingSubsystemsTechnology.BMCGenomics.9:75.http://www.biomedcentral.com/1471-2164/9/75

21. DeJonghM,FormsmaK*,BoillotP*,GouldJ*,RycengaM*andBestA.(2007)Towardtheautomatedgenerationofgenome-scalemetabolicmodelsintheSEED.BMCBioinform.8:139.http://www.biomedcentral.com/1471-2105/8/139/

22. MorrisonHG,McArthurAG,GillinFD,AleySB,AdamRD,OlsenGJ,BestAA,CandeWZ,ChenF,CiprianoMJ,DavidsBJ,DawsonSC,ElmendorfHG,HehlAB,HolderME,HuseSM,KimUU,Lasek-NesselquistE,ManningG,NigamA,NixonJEJ,PalmD,


PassamaneckNE,PrabhuA,ReichCI,ReinerDS,SamuelsonJ,SvardSGandSoginML.(2007)Genomicminimalismintheearlydiverging,intestinalparasite,Giardialamblia.Science.317:1921-1926.http://www.sciencemag.org/cgi/content/abstract/317/5846/1921

23. BestAA,MorrisonHG,McArthurAG,SoginMLandOlsenGJ.(2004)Evolutionoftranscription:insightsfromthegenomeofGiardialamblia.GenomeRes.14:1537-1547.http://www.genome.org/cgi/content/full/14/8/1537

24. BestAAandOlsenGJ.(2001)SimilarsubunitarchitectureofarchaealandeukaryalRNApolymerases.FEMSMicrobiolLett.195:85-90.http://www.blackwell-synergy.com/doi/full/10.1111/j.1574-6968.2001.tb10502.x

BookContributions,Reviews,CommentariesandGenomeAnnouncements

1. AndersK,BarekziN,BestAA,FrederickG,MavrodiD,etal*.(2017)GenomeSequencesofMycobacteriophagesAmgine,Amohnition,Bella96,Cain,DarthP,Hammy,Krueger,LastHope,Peanam,PhelpsODU,Phrank,SirPhilip,SlimphazieandUnicorn.GenomeAnnounc.5:e01202-17.*Includes31UndergraduateStudentAuthorshttp://genomea.asm.org/content/5/49/e01202-17.full

2. KazmierczakRA,BestAA,NguyenD*,EisenstarkA.(2017)Whole-GenomeShotgunSequencesofSalmonellaentericaSerovarTyphimuriumLilleengenTypeStrainsLT1,LT18,LT19,LT20,LT21,andLT22.GenomeAnnounc.5:e00720-17.https://doi.org/10.1128/genomeA.00720-17

3. DevoidS,OverbeekR,DeJonghM,VonsteinV,BestAA,HenryC.(2013)AutomatedGenomeAnnotationandMetabolicModelReconstructionintheSEEDandModelSEED.inAlperH.S.etal.(eds)SystemsMetabolicEngineering:MethodsandProtocols,MethodsMol.Biol.985:17-45.http://link.springer.com/protocol/10.1007/978-1-62703-299-5_2

4. BestAAandHarbourDV.(2012)VirtualLaboratoryMeetsCase-BasedInstructionJ.Microbiol.&Biol.Edu.13:469.

5. HenryCS,OverbeekRA,XiaF,BestAA,GlassE,GilbertJA,LarsenPE,EdwardsR,DiszT,MeyerF,VonsteinV,DeJonghM,BartelsD,DsaiN,D’SouzaM,DevoidS,KeeganKP,OlsonR,WilkeA,WilkeningJandStevensRL.(2011)ConnectingGenotypetoPhenotypeintheEraofHigh-throughputSequencing.Biochim.Biophys.Acta.1810:967-977.http://www.sciencedirect.com/science/article/pii/S0304416511000596

6. BestAA,DejonghM,BartonAJ,BrownJRandBarneyCC.(2007)ModelsofInterdisciplinaryResearchandServiceLearningatHopeCollege.CURQuarterly.28:18-23.

Pre-Prints

1. DisselkoenC,HekmanN*,DeJonghM,BestAAandTintleN.(2017)BayesianGeneActivityStateEstimationfromGenome-WideTranscriptomicsData.bioRxiv24100doi:https://doi.org/10.1101/241000

2. ArkinAP,StevensRL,CottinghamRW,MaslovS,HenryCS,etal.(2016)TheDOESystemsBiologyKnowledgebase(KBase).bioRxiv096354doi:https://doi.org/10.1101/096354


SelectedPublicDatasetsOriginatingfromClassroomBasedResearchProjects1. Peirce,C.E.*,Best,A.,Stukey,J.,Barber,A.J.*,Chew,R.D.*,Corajod,J.M.*,Georges,A.E.*,

Harmon,C.J.*,Hildebrandt,E.N.*,Jansen,E.C.*,Knutter,J.Z.*,Kraay,B.A.*,LaRoche,J.R.*,Long,C.A.*,Murray,C.E.*,Peterson,L.J.*,Rose,A.C.*,Schipper,D.J.*,Simmons,J.M.*,Sjoholm,R.L.*,Slette,I.J.*,Willis,A.N.*,Davenport,K.,Chertkov,O.,Goodwin,L.,Green,L.,Rogers,Y.,Tapia,R.,Brettin,T.,Detter,C.,Han,C.,Bradley,K.W.,Khaja,R.,Lewis,M.F.,Barker,L.P.,Jordan,T.C.,Ko,C.,Russell,D.A.,Bowman,C.A.,Jacobs-Sera,D.,Hendrix,R.W.andHatfull,G.F.(2009)CompletegenomesequenceofMycobacteriophagePumpkin.GenBank:GQ303265.

2. Ludwig,M.L.*,Best,A.,Stukey,J.,Baxter,C.E.*,Dobbs,H.A.*,Endean,T.B.*,Gasparotto,A.C.*,Genzink,K.A.*,Gerometta,E.A.*,Goodman,D.E.*,Kozack,J.C.*,LaBarge,L.M.*,Lewinski,J.L.*,Wieringa,J.G.*,Willey,M.R.*,Yancey,H.E.*,Zhang,X.*,Meincke,L.J.,Goodwin,L.A.,Detter,J.C.,Han,S.,Green,L.D.,Bradley,K.W.,Khaja,R.,Lewis,M.F.,Barker,L.P.,Jordan,T.C.,Russell,D.A.,Leuba,K.D.,Fritz,M.J.,Bowman,C.A.,Pope,W.H.,Jacobs-Sera,D.,Hendrix,R.W.andHatfull,G.F.(2011)CompletegenomesequenceofMycobacteriophageVix.GenBank:JF704114.

3. Karssen,M.P.*,Best,A.,Stukey,J.,D'Addario,T.J.*,Day,A.S.*,Deeg,C.E.*,Johnson,L.E.*,Leonard,B.R.*,Neilands,D.A.*,Owens,N.D.*,Schuman,J.A.*,Stukel,M.G.*,Tans,L.M.*,Thomas,M.K.*,Ulmer,M.R.*,VanWynen,C.M.*,Vessells,D.W.*,Viveen,V.D.*,Weiss,M.P*.,Anders,K.R.,Braun,M.A.,Delesalle,V.A.,Hughes,L.E.,Ware,V.C.,Bradley,K.W.,Barker,L.P.,Asai,D.J.,Bowman,C.A.,Russell,D.A.,Pope,W.H.,Jacobs-Sera,D.,Hendrix,R.W.andHatfull,G.F.(2014)CompletegenomesequenceofMycobacteriophageInventum.GenBank:KM066034.

SelectedPresentationsNationalConferenceswithUndergraduateStudents(studentsindicatedbyasterisk)

1. PritchardS*,Hughes,M*,PayneC*,RagonL*andBestAA.GenomicandPhysiologicalCharacteristicsofNovelEscherichiaStrainsIsolatedfromFreshWaterSources.AmericanSocietyforMicrobiologyMicrobe.NewOrleans,LA,June2017.

2. HughesM*,RagonL*,LeeK*,PikaartM,PeasleeGFandBestAA.GenomicCharacterizationofEscherichiaIsolatesfromaWatershed.AmericanSocietyforMicrobiologyMicrobe.Boston,MA,June2016.

3. CushmanK*andFischmanH*.LysisCassetteMosaicismandPotentialExpandedHostRangeEvidentintheGenomesofGlassandBella96.7thAnnualSEA-PHAGESSymposiumHHMIJaneliaResearchCampus,Washington,D.C.,June2015.

4. ValesanoAL*andBestAA.TranscriptomeProfilingoftheLifeCycleofGiardialambliausingRNA-Seq.14thAnnualBeckmanSymposium,Irvine,CA,August2014.

5. ValesanoAL*andBestAA.TranscriptomeProfilingoftheLifeCycleofGiardialambliausingRNA-Seq.AmericanSocietyforMicrobiology114thGeneralMeeting,Boston,MA,May2014.

6. DeegCE*,SchulzW*,EguiluzM*,StukeyJandBestAA.RefiningRestrictionEnzymeDigestionStrategiestoIdentifyClusterMembershipofNewlyIsolatedMycobacteriophages.AmericanSocietyforMicrobiology114thGeneralMeeting,Boston,MA,May2014.


7. DeegC*.RefiningRestrictionEnzymeDigestionStrategiestoIdentifyClusterMembershipofNewlyIsolatedMycobacteriophages.5thAnnualSEA-PHAGESSymposiumHHMIJaneliaFarm,Washington,D.C.,June2013.

8. DeegC*.Isolationof20MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Inventum.5thAnnualSEA-PHAGESSymposium,HHMIJaneliaFarm,Washington,D.C.,June2013.

9. McLellanLK*,WoodigaSA,KingSJ,RodionovDandBestAA.RegulationofHyaluronicAcidMetabolisminStreptococcuspneumoniaebyRegR.AmericanSocietyforMicrobiology113thGeneralMeeting,Denver,CO,May2013.

10. ValesanoAL*,EguiluzM*andBestAA.ComparativeAnalysisof26GenomeScaleMetabolicModelsoftheGenusShewanella.AmericanSocietyforMicrobiology113thGeneralMeeting,Denver,CO,May2013.

11. McLellanLK*.Isolationof20MycobacteriophagesandGenomicAnalysisofPhineas,aMemberoftheNewlyFormedClusterP.4thAnnualSEA-PHAGESSymposium,HHMIJaneliaFarm,Washington,D.C.,June2012.

12. KozackJ*,PhageGenomicsResearchGroup*(131stYearStudents),StukeyJandBestAA.IsolationandGenomeSequencingofTwoNovelMycobacteriophage,EnderandVix.Poster.AmericanSocietyforMicrobiology110thGeneralMeeting,SanDiego,CA,May2010.(originatingfromclassroomlaboratory)

13. DobbsH*.IsolationandGenomeSequencingofTwoNovelMycobacteriophage,EnderandVix.OralPresentation.2ndAnnualNationalGenomicsResearchInitiativeSymposium.HHMIJaneliaFarmResearchCampus,Ashburn,VA,June2010.

14. GeorgesA*.IsolationandGenomceSequencingofaNovelMycobacteriophage,Pumpkin.OralPresentation.1stAnnualNationalGenomicsResearchInitiativeSymposium.HHMIJaneliaFarmResearchCampus,Ashburn,VA,June2009.

15. -JansenEC*,PeirceC*,PhageGenomicsResearchGroup*(181stYearStudents),StukeyJandBestAA.IsolationandGenomeSequencingofaNovelMycobacteriophage,Pumpkin.Poster.AmericanSocietyforMicrobiology109thGeneralMeeting,Philadelphia,PA,May2009.(originatingfromclassroomlaboratory)

16. HenryC,BestAA,DeJonghM,FrybargerP*andStevensR.High-throughputReconstructionandOptimizationof100NewGenome-scaleMetabolicModels.Poster.AmericanSocietyforMicrobiology109thGeneralMeeting,Philadelphia,PA,May2009.

17. BowermanN*,McPhersonN*,DeJonghMandBestAA.AutomatedAssignmentofMetabolicCapabilitiesforSequencedMicrobesBasedonGenomeAnnotation.Poster.AmericanSocietyforMicrobiology109thGeneralMeeting,Philadelphia,PA,May2009.

18. FrybargerP*,HenryC,DeJonghM,StevensRandBestAA.Reconstruction,OptimizationandCurationof100NewGenome-scaleMetabolicModels.Poster.RECOMB-BioinformaticsEducation,UniversityofCaliforniaSanDiego,LaJolla,CA,March2009.

19. StantonKM*andBestAA.ValidationofmissinggenefunctionsintherhamnosemetabolicpathwayofBacillus,SalmonellaandStreptomyces.AmericanSocietyforMicrobiology108thGeneralMeeting.Boston,MA,June2008.

20. BestAA,DeJonghM,BoillotP*,BowermanN*,FormsmaK*,FrybargerP*andWilkeningJ*.TowardtheAutomatedGenerationofGenome-scaleMetabolic


NetworksintheSEED.Poster.AmericanSocietyforMicrobiology107thGeneralMeeting,TorontoON,May2007.(Note:Iwasthepresenteratthismeeting)

21. SarriaI*,HoltropMF*,BushZJ*,LaphamLL*andBestAA.UniqueTranscription22. MechanismofGiardialamblia.Poster.AmericanSocietyforMicrobiology106th

GeneralMeeting,OrlandoFL,May2006.23. SarriaI*,HoltropM*andBestA.UniqueTranscriptionMechanismofGiardia

lamblia.OralPresentation.AnnualBiomedicalResearchConferenceforMinorityStudents,AtlantaGA,November2005.

LocalandRegionalConferenceswithUndergraduateStudents

(Forthesepresentations,a“-“atthebeginningofthereferenceindicatesaprojectconductedsolelyinaclassroomlaboratoryatthetimeofthepresentation)1. PritchardS*,RagonL*,HughesM*,MillerC*,AcostaA*,MorganC*,MullenB*,

RosemaD*,SmithG*,SpeetJ*,ThomasR*,WhitmoreN*andWinterN*.GenomicCharacteristicsofEscherichiacoliIsolatesfromtheMacatawaWatershed.14thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2015.

2. –DalmanM*,FischmanH*,FletcherE*,FranzK*,GuillaumeJ*,HardyE*,JeavonsA*,JurikC*,KrahnA*,MachayA*,Mejicano-GormelyE*,PetrovichM*,PlatteC*,RichA*,RoyerJ*,TheisMC*,VelaN*andDeegC*.Isolationof35MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Glass.14thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2015.

3. –BelykK*,ConroyJ*,CushmanK*,ElliottM*,FiferJ*,GitterS*,GuttingA*,KainE*,KosibaD*,LeeS*,NguyenK*,ParliamentN*,ReitsmaH*,SieversM*,TalagaS*,VersluisP*,YoonYC*,ZickR*andBogolinM*.Isolationof35MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Bella96.14thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2015.

4. -AlexanderC*,DeGlopperK*,DornS*,EnsinkE*,GagerC*,HenryR*,MasiakA*,MayR*,MoffatS*,SchaarC*,SellersL*andTrentadueK*.Isolationof32MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Roscoe.13thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2014.

5. -BanaszakE*,BogolinB*,BordeauxJ*,BottomleyM*,BulthuisK*,CollinsJ*,CunninghamM*,HarrisS*,HodgsonK*,Klochko-BullJ*,KnolJ*,LunderbergD*,MerrimanB*,NurenbergE*,OttemanC*,RhodesA*,StamasH*andTealL*.Isolationof32MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Minnie.13thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2014.

6. AtwellM*,BlystraD*,MillerC*,MorrowA*,PritchardS*andSheasleyL*.PhysiologicalandGenomicCharacteristicsofEscherichiacoliIsolatesfromtheMacatawaWatershed.13thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2014.


7. ValesanoAL*.Genome-wideanalysisoftranscriptionfactorbindinginGiardialamblia.WestMichiganRegionalUndergraduateScienceResearchConference,VanAndelResearchInstitute,GrandRapids,MI,November2013.

8. MillerC*.CharacterizationofNewMicrobialPopulationsintheMacatawaWatershed.PEWUndergraduateResearchSymposiumintheBiologicalSciencesandPsychology.St.Louis,MO,November2013.

9. ValesanoAL*.Genome-wideanalysisoftranscriptionfactorbindinginGiardialamblia.PEWUndergraduateResearchSymposiumintheBiologicalSciencesandPsychology,St.Louis,MO,November2013.

10. McLellanLK*.RegulationofHyaluronicAcidMetabolisminStreptococcuspneumoniaebyRegR.12thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2013.

11. EguiluzMB*andValesanoAL*.ComparativeAnalysisof26GenomeScaleMetabolicModelsoftheGenusShewanella.12thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2013.

12. -D’AddarioTJ*,DayA*,DeegC*,etal.(17firstyearstudents*).Isolationof20MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Inventum.12thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,April2013.

13. ShadesK*.DeterminationofPutativeDNABindingSitesforVirulenceFactorRegRinStreptococcus.11thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,Holland,MI,April2012.

14. -EguiluzMB*,GageMR*,HederstedtER*,etal.(17firstyearstudents*).Isolationof20MycobacteriophagesandGenomicAnalysisoftheNovelMycobacteriophage,Phineas.11thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,Holland,MI,April2012.

15. EguiluzMB*.TamingoftheShew–MetabolicModelingoftheGenusShewanellaPEWUndergraduateResearchSymposiumintheBiologicalSciencesandPsychology,Chicago,IL,November,2012.

16. McLellanLK*.RegulationofHyaluronicAcidMetabolisminStreptococcuspneumoniaebyRegR.WestMichiganRegionalUndergraduateScienceResearchConference,VanAndelResearchInstitute,GrandRapids,MI,November2012.

17. ValesanoAL*.MetabolicModelingoftheGenusShewanellaUsingtheModelSEED.WestMichiganRegionalUndergraduateScienceResearchConferenceVanAndelResearchInstitute,GrandRapids,MI,November2012.

18. JansenE*andBestAA*.ScreeningExtractsfromtheTropicalPioneerPlantsBocconiafrutescens,Guettardapoasana,andPhytolaccarivinoidesforAnti-ParasiticActivity.10thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,Holland,MI,April2011.

19. PeirceC*andBestAA*.GenerationandComparativeAnalysesofGenome-scaleMetabolicModelsfortheGenusShewanellausingtheModelSEED.10thAnnualHopeCollegeCelebrationforUndergraduateResearchandCreativePerformance,Holland,MI,April2011.

20. HicksCA*andBestAA*.SuspectedFunctionoftheArchaealClusteroftheGHMPKinaseSuperfamilyasCharacterizedbyMethanococcusmaripaludisandSalinibacter


ruber.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

21. EdewaardK*andBestAA*.IdentifyingTranscriptionFactorBindingSitesinGiardialamblia.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

22. -NickolsA*,VanderVeenG*,BoydK*andLewisS*.PredictedRegulonsofPdhRandPsrAinShewanellaoneidensis.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

23. -TapperIIDF*,EastburgLC*,AgauasSJ*,MorricalEB*andPeirceC*.PredictedTranscriptionFactorBindingSitesofFadRReguloninS.oneidensisUnsubstantiatedinEMSA.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

24. -BeckerJP*,BowermanNC*,ConstantJR*,KosibaSL*andPeirceC*.VerifyingthePredictedTranscriptionFactor,PsrA,andItsPredictedBindingSitesinShewanellaoneidensis.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreative Performance,Holland,MI,April2010.

25. -DeYoungJT*,ShierSE*,SlenkNC*,ColburnT*andPeirceC*.EffectofProlineintheExpressionofthePredictedHypRReguloninShewanellaoneidensis.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

26. -BaxterC*,DobbsH*,EndeanT*,GasparottoA*,GenzinkK*,GeromettaE*,GoodmanD*,KozackJ*,LaBargeL*,LewinskiJ*,LudwigM*,WieringaJ*,WilleyM*andYanceyH*.IsolationandGenomeSequencingofTwoNovelMycobacteriophages,EnderandVix.Poster.9thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2010.

27. DonkerslootJ*,GuerraJr.L*,LamphearB*,PikaartMandBestAA.UbiquitylationofHistoneH2BinGiardialamblia.UniversityofNotreDame,SouthBend,IN,July2009.

28. -BarrusJ*,DeHaanC*,LewisJ*,WestcottA*andBestAA.InvestigationoftheCorrelationBetweenGeneClusteringandBiochemicalActivityofPduXinStreptomycescoelicolorandListeriainnocua.Poster.8thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

29. BowermanN*,McPhersonN*andBestAA.AutomatedAssignmentofMetabolicCapabilitiesforSequencedMicrobesBasedonGenomeAnnotation.Poster.8thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

30. FrybargerP*,DeJonghMandBestAA.High-throughputReconstructionandOptimizationof100NewGenome-scaleMetabolicModels.Poster.8thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

31. -HicksC*,LewisB*,PhillipsT*,VanderMaasM*andBestAA.PredictedRoleofPantothenateKinase4inCoenzymeABiosynthesisfromM.maripaludisandS.ruber.Poster.8thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

32. -MaddenJ*,ParrottS*,PoelN*,SalasT*andBestAA.IdentifyingSubstrateBindingSpecificityofaGHMPKinaseinThermoplasmaacidophilum.Poster.8thAnnualHope


CollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

33. -PeirceC*,BarberA*,ChewR*,CorajodJ*,GeorgesA*,HarmonC*,HildebrandtE*,JansenE*,KnutterJ*,KraayB*,LaRocheJ*,LongC*,MurrayC*,PetersonL*,RoseA*,SchipperD*,SimmonsJ*,SjoholmR*,SletteI*,WillisA*,StukeyJandBestAA.IsolationandGenomeSequencingofaNoveMycobacteriophage,Pumpkin.Poster.8thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,April2009.

34. LamphearBR*,BowermanNC*andBestAA.IdentifyingTranscriptionFactorBindingSitesinGiardialamblia.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

35. StantonKM*andBestAA.ValidationofMissingGeneFunctionsintheRhamnoseMetabolicPathway.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

36. BowermanNC*andBestAA.AutomatedGenerationandManualCurationofaMetabolicModelforShewanellaoneidensisMR-1.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

37. ChavezA*andBestAA.PredictedN-formyl-L-glutamateDeformylaseinHistidineCatabolism.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

38. -LyonsJ*,McNeilA*,SeriniJ*,TreolarN*andBestAA.PredictedL-threonineKinaseforB12Biosynthesis.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

39. -BarberioK*,LeeK-H*,PepperA*,SlaughterJ*andBestAA.PredictedRoleofDapEintheArginineMetabolicPathway.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

40. -GardnerD*,KouJ*,MeidemaT*,MorganE*andBestAA.GeneticAnalysisofaPredictedDualRoleofDapEintheArginineandLysineBiosynthesisPathways.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

41. -EllsworthK*,GoltzA*,JansmaA*,McConnellyE*andBestAA.MissingGene,N-formylglutamateDeformylase(nfoD)intheHistidineDegradationPathway.Poster.7thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,March2008.

42. BowermanNC*,LamphearBR*,andBestAA.IdentifyingTranscriptionFactorBindingSitesinGiardialamblia.Poster.PEWUndergraduateResearchSymposium,St.Louis,MO,November2007.

43. BowermanNC*,LamphearBR*,andBestAA.IdentifyingTranscriptionFactorBindingSitesinGiardialamblia.Poster.WestMichiganUndergraduateScienceResearch Conference,VanAndelInstitute,GrandRapids,MI,October2007.

44. -HeeremaS*,HessK*,JanczakK*,VickeryJ*andBestAA.ExaminationofaPredictedL-threonineKinaseRequiredforCoenzymeB-12BiosynthesisinStreptomycescoelicolorandSalmonellatyphimurium.Poster.6thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,January2007.


45. -GreenM*,HarrierS*,HaumillerW*,NicholsA*andBestAA.DeterminationofrhaZFunctioninL-rhamnoseUtilizationinSalmonellatyphimurium.Poster.6thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,January2007.

46. -LienM*,OosterhouseE*,StantonK*,GendronM*andBestAA.PredictedRolesofRhaEandRhaWDomainsinFusedYuxGintheRhamnoseMetabolicPathway.Poster.6thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,January2007.

47. -CooperA*,DeHaanJ*,EngersW*,VoylesA*andBestAA.PredictedAlternativeN-formylglutamateDeformylaseinHistidineCatabolism.Poster.6thAnnualHopeCollegeCelebrationofUndergraduateResearchandCreativePerformance,Holland,MI,January2007.

48. VanBeekM*,HekmanJ*,KrasityB*andBestA.IdentifyingTranscriptionFactorBindingSitesinGiardialamblia.Poster.PEWUndergraduateResearchSymposium,Chicago,IL,November2006.

49. HoltropM*,SarriaI*andBestA.TheUniqueMechanismofTranscriptioninGiardialamblia.Poster.5thAnnualCelebrationofUndergraduateResearchandCreativePerformance,HollandMI,January2006.

50. GonthierSJ*andBestAA.ASoftwareEnvironmentfortheAnalysisofProteinSequenceMotifs.Poster.5thAnnualCelebrationofUndergraduateResearchandCreativePerformance,HollandMI,January2006.

51. AmbroseJR*,FormsmaKS*,GouldJA*,BestAAandDeJonghM.IntegrationofKEGGPathwaysintotheSEED.OralPresentation.16thAnnualArgonneSymposiumforUndergraduatesinScience,EngineeringandMathematics,ArgonneIL,November2005.

NationalConferenceAbstractswithoutUndergraduateStudents

1. DeJonghM,BestA,TintleNandHenryC.IntegrationofTranscriptomicDataandMetabolicModelsforExpression-InformedFlux-BalanceAnalysis.COBRA2015,4thConferenceonConstraint-BasedReconstructionandAnalysis.Heidelberg,Germany,September2015.

2. MarshallC,O’BrienS,KemnerK,O’LoughlinE,BestAandGilbertJ.MicrobialEcologyofRestoredWetlandsatVariousStagesofMaturityandFloodingFrequency.AmericanSocietyforMicrobiology115thGeneralMeeting,NewOrleans,LA,June2015.

3. HenryC,DehalP,BaumolJ,BestA,BischofJ,etal.MetabolicModelingintheDOESystemsBiologyKnowledgebase.COBRA20143rdConferenceonConstraint-BasedReconstructionandAnalysis.Charlottesville,VA,May2014.

4. HenryC,DeJonghM,BestAandStevensR.High-throughputReconstructionandOptimizationof130NewGenome-ScaleMetabolicModels.2009AIChEAnnualMeeting,Nashville,TN,November2009.

5. BestAAandStukeyJ.HopeCollegePhageGenomicsResearchCourse:FirstYearImplementationandResults.Poster.1stAnnualNationalGenomicsResearchInitiativeSymposium.HHMIJaneliaFarmResearchCampus,Ashburn,VA,June2009.


6. BestAA,DeJonghMandKruegerB.IntegratingBioinformaticsandComputationalModelingintotheBiologyCurriculumatHopeCollege.Poster.RECOMB-BioinformaticsEducation,UniversityofCaliforniaSanDiego,LaJolla,CA,March2009.

7. DeJonghMandBestAA.TowardtheAutomaticGenerationofGenome-scaleMetabolicModelsintheSEED.Poster.DOEJointGenomics:GTLAwardeeWorkshopV,Bethesda,MD,2007.

8. BestAAandDeJonghM.AResearch-basedApproachtoTeachingBioinformatics:MicrobialGenomeAnnotationandMetabolicModelingusingtheSEED.Poster.AmericanSocietyforMicrobiologyConferenceforUndergraduateEducators(ASMCUE),OrlandoFL,May2006.

9. BestAAandWoeseCR.Definingmicrobialrelationshipswithcompletegenomes:theeuryarchaealcrown.Poster.AmericanSocietyforMicrobiology104thGeneralMeeting,NewOrleansLA,May2004.

10. BestAAandOlsenGJ.Evolutionoftranscription:insightsfromthegenomeofGiardialamblia.Poster.AmericanSocietyforMicrobiology102ndGeneralMeeting,SaltLakeCityUT,May2002.

11. BestAAandOlsenGJ.Agenome-widesearchforarchaealpromoterelements.Poster.NinthDOEGenomeContractorandGranteeWorkshop,OaklandCA,January,2002.

12. BestAAandOlsenGJ.Bioinformaticsforgenomeanalysis.Poster.NinthDOEGenomeContractorandGranteeWorkshop,OaklandCA,January,2002.

13. BestAAandOlsenGJ.Genetransfer:pastandpresent.Poster.NinthDOEGenomeContractorandGranteeWorkshop,OaklandCA,January,2002.

14. BestAAandOlsenGJ.PolyadenylationofmRNAtranscriptsinArchaea.CellandMolecularBiologyTrainingGrantSymposium,UniversityofIllinois,October2001.

15. BestAAandOlsenGJ.SubunitinteractionsofanarchaealRNApolymeraseandrelationshipstoeucarya.Poster.AmericanSocietyforMicrobiology99thGeneralMeeting,ChicagoIL,May1999

InvitedOralPresentations

1. MacatawaWatershedEscherichiacoliLevelsandPopulationGenomics.InvitedTalk.OttawaCountyWaterQualityForum,WestOlive,MI,November2017.BestA.

2. LongitudinalMonitoringofBacterialPopulationsandNutrientLoadsintheMacatawaWatershed.InvitedSeminar.DepartmentofBiology,DordtCollege,SiouxCenter,IA,November2017.BestA.

3. LongitudinalMonitoringofMicrobialPopulationsandNutrientLoadsintheMacatawaWatershed.InvitedTalk.IAGLR2017,Detroit,MI,May2017.BestA.

4. IdentificationandAnalysisofBacterialGenomicMetabolicSignatures.InvitedPaperPresentation.PacificSymposiumonBiocomputing2017,TheBigIsland,HI,January2017.BestA.

5. IntegratingTeachingandResearchatPrimarilyUndergraduateInstitutions:Challenging,Achievable,Rewarding.InvitedSeminar.DepartmentofMicrobiologyandImmunologySeminarSeries,UniversityofMichigan,AnnArbor,MI,November2016.BestA.


6. TheDynamicsandInterpretationofMicrobiomeData.InvitedSeminar.PoultryScienceAssociation.NewOrleans,LA,July2016.BestA.

7. SEAzethePhage:EvolutionofFirstYearSTEMEducationatHopeCollege.InvitedPlenaryLectureattheMichiganAmericanSocietyforMicrobiologySpringMeeting2016:FrontiersinMicrobiologyEducation.GrandRapids,MI,April2016.StukeyJandBestA.

8. FundingandFacilitatingYourResearch.InvitedWorkshopSpeakerandDiscussionLeaderforthe“Gettingstartedasamicrobiologistataprimarilyundergraduateinstitution(PUI)”WorkshopattheAmericanSocietyforMicrobiology114thGeneralMeeting,Boston,MA,May2014.BestAAandKingR.

9. IntegratingScienceandEducationPanelDiscussion.InvitedPanelParticipantatthe2013HHMISEA-PHAGESInSilicoWorkshop,HHMIHeadquarters,ChevyChase,MD,December2013.BestAA.

10. TheMetabolicLandscapeofSequencedMicrobes.Fall2013DepartmentofBiochemistrySeminarSeries,UniversityofMissouri,Columbia,MO,October2013.BestAA.

11. IncorporatingYourResearchIntoYourTeaching.InvitedPanelParticipantattheSecondBiennialMidwestP3Workshop:PostdoctoPUIProfessor,HopeCollege,Holland,MI,April2013.BestAA.

12. TheMetabolicLandscapeofSequencedMicrobes.KeynoteSpeakerforthe2012MicrobiologyResearchConference,UniversityofIllinoisatUrbana-Champaign,October2012.BestAA.

13. MetabolicReconstructionandModelingofSequencedMicrobesintheContextofUndergraduateEducation.AmericanSocietyforMicrobiologySymposium“FunctionalGenomicsintheClassroom”attheAmericanSocietyforMicrobiology110thGeneralMeeting,SanDiego,CA,May2010.BestAA.

14. PatchingHolesinMetabolicNetworks:IdentificationandValidationofNovelEnzymesinRhamnoseCatabolism.Spring2010DepartmentofBiochemistrySeminarSeries,WayneStateUniversity,Detroit,MI,March2010.BestAA.

15. InterdisciplinaryResearchAcrossBiology,MathematicsandComputerScience:Genome-scaleMetabolicReconstructionandModelingofMicrobialLife.MidstatesConsortiumforMathematicsandScience:InterdisciplinaryScienceEducation,St.OlafCollege,Northfield,MN,January2007.BestAA,DeJonghMandTintleN.

16. CombiningAutomatedGenome-scaleMetabolicModelGenerationwithPredictionandValidationofGeneFunctionintheContextofUndergraduateEducation.DOEJointGenomics:GTLAwardeeWorkshopV,Bethesda,MD,February2007.BestAA.

17. Genome-scaleMetabolicReconstructionandModelingofMicrobialLife.HHMIInterdisciplinaryLecture,HopeCollegeSummerResearchProgram,June2007.BestAA,DeJonghMandTintleN.

18. FormingLinkswithDisciplinarySocieties.ProjectKaleidoscope(PKAL)F21Meeting,ChicagoIL,2006.BestAA.

19. BioinformaticsatHopeCollege.AlbionCollege,DepartmentofBiology,March2005.BestAAandDeJonghM.

20. EvolutionoftranscriptioninArchaeaandtheearly-divergingeukaryote,Giardialamblia.UniversityofIllinoisDepartmentofMicrobiology,November2001.BestAA.


21. SimilarsubunitarchitectureofarchaealandeukaryalRNApolymerases.UniversityofIllinoisDepartmentofMicrobiology,October2000.BestAA.

22. Assessingphylogeneticrelationshipsamongredalgaeusing18SribosomalDNA.MissouriAcademyofSciences,Springfield,MO,April1996.BestAA.

Media,PublicPresentationsandOutreach

1. HopeCollegeDay1ResearchCommunities.RecruitingandPromotionalVideo.Aidedindesign/production,releasedDecember2017.https://youtu.be/j5Vk96JH4Pk

2. HopeCollegeDay1ResearchCommunities–Watershed.RecruitingandPromotionalVideo.Interviewedforandaidedindesign/production,releasedNovember2017.https://youtu.be/na31bzrJpSk

3. Hands-OnLearningfromDay1andBeyond.Interviewedfor“NewsfromHopeCollege”magazine,releasedspring2017.https://magazine.hope.edu/spring-2017/day1/

4. MajorGrantSupportsComprehensiveStudyofE.coliinMacatawaWatershed.InterviewedforHopeCollegeNews,releasedSeptember2016.http://www.hope.edu/news/2016/research/major-nsf-grant-supports-comprehensive-study-of-e-coli-in-macatawa-watershed.html

5. StudentResearchandDevelopmentfromDay1.InterviewedforHopeCollege“StoriesofHope”Blog,releasedApril2016.https://blogs.hope.edu/stories-of-hope/natural-and-applied-sciences/student-research-and-development-from-day-1/

6. Abrightfuture…MariaEguiluz.InterviewedforHopeCollegepromotionalvideohighlightingstudentsuccess,releasedJanuary2015.http://www.hope.edu/bright-future

7. ThroughtheSequencingRevolution:RevealingtheUnseenSelf.DepartmentSponsoredSessionaspartofHopeCollege2014CriticalIssuesSymposium–“TechnologyandtheFutureofBeingHuman”,HopeCollege,Holland,MI,September2014.InvitedSeminar.BestAA.

8. HopeCollege:CollaborativeStudentResearchandLeadingEdgeTechnology.IndianapolisHopeCollegeAlumniAssociation,Indianapolis,IN,May2014.BestAA.

9. MacatawaWatershedWaterQualityStudy.OttawaCountyEighthAnnualWaterQualityForum,WestOlive,MI,November2013.InvitedSeminar.BestAA,PikaartMandPeasleeG.

10. NSFFundsIntegratedMetabolicandRegulatoryModelingGrant.InterviewedforHopeTodayNews,releasedOctober2013.http://www.hope.edu/2013/10/22/nsf-funds-integrated-metabolic-and-regulatory-modeling-grant

11. Biologyinthe21stCentury.HarrisonC.andMaryL.VisscherEndowedChairinGeneticsInvestitureCeremony,HopeCollege,September2012.InvestitureLecture.BestAA.

12. “Next-Generation”GenomicSequencerWillEnhanceProgram.InterviewedforHopeTodayNews,releasedAugust2012.http://www.hope.edu/2012/08/16/next-generation-genomic-sequencer-will-enhance-program


13. AaronBestAppointedtoNewVisscherProfessorshipinGenetics.InterviewedforHopeTodayNews,releasedAugust2012.http://www.hope.edu/2012/08/01/aaron-best-appointed-new-visscher-professorship-genetics

14. NewSoftwareSpeedsGenomeAnalysis.InterviewedforHopeTodayNews,releasedOctober2012.http://www.hope.edu/2010/10/05/new-software-speeds-genome-analysis

15. ResearchOutoftheGate.InterviewedforCampusProfilearticlein“NewsfromHopeCollege”magazine,April2010.ArticledescribingPhageGenomicsResearchInitiativeatHopeCollege.

16. MicrobialHitchhikersandtheHumanGenome:HowMuchofYouisYou?HopeCollege2009AlumniWeekendAlumniCollegeLecture,May2009.InvitedSeminar.BestAA.

17. FortyUnder40.FeatureinterviewfortheHollandSentinelcommunityoverview“Focus2008”publication,March,2008

18. InterviewedforFox17News“OnCampus”segmentdescribingtheHHMIScienceEducationAllianceNationalGenomicsResearchInitiative,PhageGenomicsResearchcourseatHopeCollege,airedJanuary,10,2008

19. HopeChosenforNationalHHMIScienceInitiative.InterviewedforHopeTodayNews,releasedDecember2007.http://www.hope.edu/2007/12/12/hope-chosen-national-hhmi-science-initiative

20. AaronBestContributestoArticlein“Science”.InterviewedforHopeTodayNews,releasedNovember2007.http://www.hope.edu/2007/11/28/aaron-best-contributes-article-science

ProfessionalServiceEditorial

1. GuestAssociateEditorforNatureFrontiersInMicrobiology,hostingtheResearchTopic,“TowardsIntegratedMetabolicandRegulatoryModelsofAllMicrobialLife.”TopicproposalapprovedbyFrontiersInEditor;Actingasleadeditorforthetopic,2014–Present.http://journal.frontiersin.org/researchtopic/3129/towards-integrated-metabolic-and-regulatory-models-of-all-microbial-life

2. EditorialBoardMember(MicrobiologySection)fortheNaturePublishingGroupinternationalopenaccessjournal,ScientificReports,2011–Present.

PeerReview

1. ExternalreviewerforPUIdepartmentofbiology2. Adhocreviewerforconfidentialtenureandpromotionpackages3. Adhocreviewerfor3-Biotech,Archaea,Bioinformatics,BMCBiotechnologyfor

Biofuels,BMCMicrobiology,F1000Research,FEMSMicrobiologyEcology,FrontiersinMicrobiology,JournalofGreatLakesResearch,NucleicAcidsResearch,PLoSOne,PLoSPathogens,ProceedingsoftheNationalAcademiesofSciences,ScientificWorldJournal

4. AdhocreviewerforgrantproposalsfortheNationalScienceFoundation5. AdhocreviewerfortheAlfredP.SloanFoundationMicrobiologyoftheBuilt

EnvironmentProgram6. AdhocreviewerfortheM.J.MurdockCharitableTrustCollegeResearchProgramfor

LifeSciences


7. ReviewerfortheHowardHughesMedicalInstituteinitiative,“TheScienceEducationAlliance”proposal

ConferenceOrganizationandWorkshopParticipation

1. Co-Organizer.“YourStudents+YourGoals+YourIdeas=YourCURE”ConcurrentEducationSessionattheAmericanSocietyforMicrobiologyConferenceforUndergraduateEducators(ASMCUE),July2018,Austin,TX.

2. Participant.“2014CUREnetConferenceonCourse-BasedUndergraduateResearchExperiences”atColdSpringHarborLaboratory.March31–April2,2014.ColdSpringHarbor,NY.

3. InvitedSpeakerandDiscussionLeader.“Gettingstartedasamicrobiologistataprimarilyundergraduateinstitution(PUI)”WorkshopattheAmericanSocietyforMicrobiology114thGeneralMeeting,Boston,MA,May17,2014.

4. InvitedPanelParticipant.2013HHMISEA-PHAGESInSilicoWorkshop,HHMIHeadquarters,ChevyChase,MD,December11-13,2013.

5. InvitedParticipant(of~30attendees).InstituteforComputinginScience(ICiS):“GenomicsDrivingModelinginBiology”.July23-30,2011.ParkCity,UT.

6. InvitedParticipant(of19attendeesrepresentingPUIs,R1UniversitiesandResearchInstitutes).HowardHughesMedicalInstituteExtendedWorkshop:“Genomics:Opportunities,ToolsandChallenges”.November2007.ChevyChase,MD.

7. Co-Chairpersonofthecommitteetoorganizethe14thAnnualAmericanSocietyofMicrobiologyConferenceforUndergraduateEducators(ASMCUE),May2007,Buffalo,NY.

ServiceatHopeCollege

DepartmentofBiology,HopeCollegeBIOL195LaboratoryCoordinator(2004and2005)AdvisingofBiologyMajors/Minors(2005-present)BiologyWebsiteAdministration(2005–present)BIOL240CurriculumRevisionCommittee(2005)ProspectiveStudentVisitationMeetings(2005–present)DeKruifAwardCommittee(2006,2007,2009)BiologySeminarSeriesCo-coordinator(2006-2007)BiologyRecruitmentandRetentionTaskForce(2007)BiologyWebsiteRevisionCommittee,Chair(2007,2008)BiologyWebsiteCommittee,Chair(2008-present)BIOL231MicrobiologyfortheAlliedHealthProfessionsLaboratoryCoordinator(2009,2010,2012,2013)SystemsBiologyTenureTrackPositionSearchCommittee(2012-2013)IntroductoryLaboratoryCurriculumRevision–GeneticsSubcommittee(2012-2013)IntroductoryLaboratoryCurriculumRevision–EvolutionSubcommittee(2012-2013)Chairperson,BIOL108IntroductoryLaboratoryCurriculumRevision–GeneticsModule,Chairperson(2013-2014)


Chairperson,BiologyTenureTrackPositionSearchCommittee(2013-2014)BiologySeminarSeriesCoordinator(2014-2015)BiologyDepartmentSchedulingCoordinator(2015-2017)

DivisionofNaturalandAppliedSciences,HopeCollege

ComputationalScienceMinorAdvisoryCommittee(2005)ComputationalScienceandModelingAdvisoryCommittee(2006-2012)ScholarshipAdvisoryCommittee–Goldwater,Udall,NSFFellowships(2008)CoordinationofInauguralVisscherLectureinGenetics–Dr.ThomasCech,speaker(2013)

CoordinationofVisscherLectureinGenetics–Dr.GrahamHatfull(2015);Dr.JenniferDoudna(2017)

BeckmanScholarResearchMentor(2013-2014)Co-investigatoroninvitedproposaltotheHerbertH.andGraceA.DowFoundation,“MeetingthePersistentChallenges:Recruiting,Retaining,andGraduatingMichiganSTEMStudents”,awarded(2014)

Co-writerofinvitedproposaltotheArnoldandMabelBeckmanFoundationBeckmanScholarProgram,awarded(2014)

HopeCollege

CulturalAffairsCommittee(2006-2007)CriticalIssuesSymposiumPlanningCommittee2008,“GlobalHealth:FromCatastrophetoCure”2009,“AtWater’sEdge:Complacency,Thirst,Action”2012,“Reconciliation:HopeinaDividedWorld”

AdvisoryCommitteeonFinancialResources(2009-2010)CommitteeonAdmissionsandFinancialAid,Chairperson(2011-present)Pre-CollegeConferencePlanningCommittee(2012)HopeCollegeWebAdvisoryGroup(2014-)StrategicPlanningStudyGroupon“EnrollmentandStudentProfile”member(2014)

AcademicandProfessionalAffiliations

MemberoftheAmericanSocietyforMicrobiology(1998–present) DivisionR–EvolutionaryandGenomicMicrobiology DivisionW–MicrobiologyEducationMemberofthePKALF21ProgramMemberoftheCouncilonUndergraduateResearch(2009–present)

UndergraduateMentoringandTeachingMentoredUndergraduateResearchers

76undergraduatestudentshavebeenmentoredinmylaboratorysincebeginningindependentcareeratHopeCollegein2004


37formerstudentsarecurrentlyingraduateprogramsorhaveadvanceddegreesinSTEMfields10formerstudentsareworkinginSTEMfields>350studentsincludedinResearchProjectsthroughCourse-basedResearchExperiences(non-overlappingwithabove)

Courses,LaboratoriesandModulesDevelopedandImplementedatHopeCollege

Professor.BIOL/CHEM195Day1:WatershedIntroductoryLaboratoryProfessor.IDS100Day1:WatershedFirstYearSeminar

HopeCollege,2015-2016,2016-2017BothSemesters

DesignedandimplementedacoursewithDr.GrahamPeaslee(HopeCollegeChemistryDepartment)forfirstyearstudentswithaninterestinscience.ThecoursecombinestheFirstYearSeminartransitiontocollegecourseatHopeCollegewithaninvestigativeyear-longCRElaboratory.Thecourseservesasanalternateintroductorybiologyandchemistrylabcredit.Theresearchisfocusedonthechemical/physicalcharacteristicsofwaterandtheirrelationshiptomicrobialpopulationsasdeterminedby16SrRNAnextgenerationsequencingdatainthelocalMacatawawatershed.Theresearchquestioniscoupledtoacommunityledremediationeffortonthewatershed.Professor.CSCI195/BIOL195IntroductiontoPythonProgramming/IntroductiontoBioinformatics

HopeCollege,2017SpringSemesters

DesignedandimplementedacoursewithcolleaguesfromComputerScience,Chemistry,Religion,HistoryandCommunicationdepartmentstointroducestudentstoprogramming.Studentstakeacomputersciencecoursefor7weekstolearnthebasicsofprogramminginpython,followedbyadisciplinaryapplicationmoduleinthedisciplineoftheirchoosing.IntheIntroductiontoBioinformaticsmodule,studentslearnthebasicsofbioinformaticsthroughprogrammingexercisesandresearchprojects.Professor.BIOL301GeneralMicrobiology

HopeCollege,2004-2009,2011-2015FallSemesters

Designedandimplementedageneralmicrobiologycourseandassociatedlaboratoryforundergraduatebiologymajors.Course-basedResearchExperiences(CREs)havebeenincorporatedintothelaboratorymoduleoverthepast10years,including:bioinformatics-drivenhypothesistestingofgenefunction,watershedmicrobialsourcetracking,watershedmicrobegenomesequencingandphysiologicalcharacterizationofisolates.Thelaboratoryiscurrentlybeingconvertedtoafullyinvestigativeapproachcenteredonthemicrobialpopulationsinthelocalwatershed.

Professor.BIOL231MicrobiologyfortheAlliedHealthProfessions

HopeCollege,2005-2007,2009,2010,2012,2013SpringSemesters


Designedandimplementedageneralmicrobiologycourseandassociatedlaboratoryforundergraduatenursingmajorsandnon-biologymajors.DesignedandimplementedinvestigativelaboratorymodulesandaninterdisciplinarycasestudyincollaborationwiththeHopeCollegeNursingDepartment.During2012and2013,taughtinlaboratoryportionofthecourseonly.

Professor.BIOL395TopicsinBioinformatics

HopeCollege,2005-2006,FallandSpringSemesters;2006,2007,2009,2012,2014FallSemestersDesignedandconductedaresearch-basedcourseinmicrobialgenomeannotationandmetabolicmodeling.Co-taughtwithDr.MatthewDeJongh,HopeCollegeComputerScienceDepartment2005-2006.Designedasaprojectbasedcourseincorporatingprogramming,algorithmdesign,andresearchquestions.

Professor.BIOL207and208HonorsLabinCellsandGenetics–PhageGenomicsResearchHopeCollege,2008-2014FullAcademicYears(primaryinSpringsemesters) IncollaborationwithDr.JosephStukey,implementedayear-longhonorscourseinphagebiologyforfirst-yearstudentsatHopeCollege.Thecourseexposesstudentstoauthenticresearchthroughisolation,molecularcharacterization,genomesequencingandbioinformaticsanalysisofphages.ThecoursewasinitiallyfundedthroughtheHHMINationalGenomicsResearchInitiative.CurrentlyfundedbyHopeCollegewithcontributionsfromHHMIandtheUniversityofPittsburgh.Primaryresponsibilityforspringsemestercoveringbioinformatics/genomics.

ModuleDevelopment.BIOL108GeneralBiologyLaboratoryII–GeneticsModule HopeCollege,2014,SpringSemester

ChairpersonoftheGeneticsModulegrouptodevelopaninvestigative,multi-weekmoduleexploringprinciplesofheredityandmoleculargenetics.Thismoduleusesmoleculartechniquestocharacterizecaninetraitdeterminingloci,exposingstudentstoDNAisolation,DNAsequencing,sequenceanalysis,andgeneticdatabases.Coordinatedinitialimplementationofmodulein2014.

Professor.CHEM395-01MethodsinModelingComplexSystems

HopeCollege,2007,SpringSemesterDesignedandimplementedacourseincollaborationwithDr.BrentKrueger,HopeCollegeChemistryDepartment,exploringtheapplicationofcomputationalmodelingtoscientificproblems.

OtherCoursesTaught

Professor.BIOL195IntroductiontoCellBiology HopeCollege,2004and2005,FallSemesters


Professor.BIOL240CellsandGeneticsLaboratory HopeCollege,2008,FallSemesterGuestLecturer.BIOCH355TechniquesinBiochemistryandBiotechnology

UniversityofIllinois,2003,FallSemesterTeachingAssistant.MolecularPhylogenyWorkshop

CentersforDiseaseControl,Atlanta,GA,September2001TeachingAssistant.MCBIO101IntroductoryMicrobiologyLaboratory

UniversityofIllinois,1996-1999,6semestersGuestLecturer.MCBIO100IntroductoryMicrobiologyLecture

UniversityofIllinois,1997-1998,SummerSessionIIAdvisor.SeniorThesisResearchandGraduateRotationProjects

UniversityofIllinois,1997-2001TeachingAssistant.MolecularBiologyLaboratoryTutorial

OxbridgeHonorsProgram,WilliamJewellCollege,Spring1996TeachingAssistant.Bio133EvolutionandEcology

WilliamJewellCollege,Fall1993,1996