21st Annual ISMRM Scientific
Meeting and Exhibition 2013
Discovery, Innovation &
Application - Advancing MR for
Improved Health
Salt Lake City, Utah, USA
20-26 April 2013
Table of Contents and Author Index
ISBN: 978-1-62993-102-9
ISSN: 1545-4428
TABLE OF CONTENTS
VOLUME 1
Optimization of Diffusion-Weighted Imaging for Body Applications 1
Dow-Mu Koh
Making the Most of3T for Body MRI 3
Shreyas S. Vasanawala
MRCP: Techniques & Pitfalls 4
David J. Lomas
Quantification of Diffuse Liver Disease Using MRI 5
Scott B. Reeder
Cirrhosis & Lesion Characterization at MR Imaging 8
ShahidM. Hussain
The Post-Treatment Liver 10
lhab R. Kamel
Imaging Algorithms for Adrenal Lesion Characterization 11
Hero K. Hussain
Renal Mass Characterization 13
Ivan Pedrosa
Functional MRI ofthe Kidney 15
Diego R. Martin
Pelvic Floor Imaging 17
KatarzynaJ. Mactira
Prostate Carcinoma: Case Studies 19
Masoom A. Haider
Tumor Metabolism 21
Kevin M. Brindle
Tumor Physiology 26
Michal Neeman
Tumor 'Omics' 27
John R. GriffithsMR in Cancer Cell Models 31
Franca Podo
MRI/MRS in Animal Models 33
Harish Poptani
Tumor Lipid Metabolism 34
Kristine Glunde
Tumor Energy Metabolism 37
Klaas Nicolay
pH in Cancer 39
Robert J. Gillies
Molecular Imaging in Cancer 40
Dmitri Artemov
Tumor Vasculature & Perfusion: Metabolic MRI 41
Charles S. Springer Jr.
Novel Contrast: CEST, Multinuclear 42
Michael T. McMahon
Cancer Treatment Response 43
Sabrina M. Ronen
ASL: Measurement 47
Maria A. Fernandez-Seara
ASL: Single Subject & Group Analysis, Including Live Demo 48
MichaelA. Chappell
ASL: Applications: Clinical, Pharma, Cognitive Neuroscience, etc 49
John A. Detre
Cross-over: Measuring Tracer Extravasation with ASL & DCE 50
Keith St. Lawrence
DCE: Measurement 51
David J. Collins
DCE Post-Processing: What Model to Use? 55
Lucy E. Kershaw
Cross-Over: Measuring the Arterial Input Function in DCE & DCS-MRI 56
Anders GarpebringDSC: Post-Processing, Including Live Demo 58
Ona Wu
What's Normal? Accounting for Population Variability 59
Guido Gerig
Drawing A Line: Multi-Variate Classification 61
Janaina Mourao-Miranda
From Group Analysis to Individual Studies: Statistical Considerations 63
Jeanette A. Mumford
Pre-Surgical Planning: Movement, Language & the Power of Localization 64
Susan Y. Bookheimer
Spatial Imaging Patterns in AD & Its Prodromal Stages Identified via Pattern Recognition Methods 66
Christos Davalzikos
Single-Subject Neuroimaging / Reliability ofMR in Psychiatric Disorders 67
John D. Port
Stroke & The Mytl. of Quantitation 68
Greg Zaharchuk
The Brain Stress Test 69
Richard B. Buxton
Real-Time fMRI, Brain States & Biofeedback 71
Xiaoping P. ffu
MRI in the Courtroom 72
Teneille R. Brown
Wrist Ligament Pathology: Diagnosis & Pitfalls 73
Kathryn J. Stevens
Glenoid Labral Tear & Normal Variation 74
Lynne S. Steinbach
What is the Rotator Interval, & Why Is It Important? 77
Michael J. Tuite
Bone Marrow Edema: Injury Patterns 78
Christine Chung
Challenges in Diagnosing Meniscal Tear in the Knee 79
Nancy M. Major
Posterolateral Corner: "The Dark Side of the Knee" 81
Tetyana A. Gorbachova
Diagnosing Hip Labral Tear: Impingement & Dysplasia 82
John A. Carrino
OCD: What Is It & How Do I Describe It? 85
Miriam A. Bredella
Optimizing MRI for Evaluation of Cartilage Injury 86
Douglas W. Goodwin
Athletic Pubalgia: The Sportsman's "Non-Hernia" 87
Adam C. Zoga
Osteomyelitis in Diabetic Feet: Can You Be Confident? 90
Sandra L. Moore
Task-Based BOLD fMRI for Presurgical Brain Mapping 93
Christoph Stippich
Resting State Functional Connectivity fMRI for Presurgical Brain Mapping 95
JoshuaS. Shimony
Diffusion Tractography: Technical Considerations for White Matter Mapping 96
Lauren J. O'Donnell
Intraoperative DTI White Matter Mapping: Neurosurgical Perspective 97
Christopher Nimsky
DTI vs. HARDI for Presurgical FiberTracking ofthe Motor Pathways 99
Jeffery I. Berman
Clinical Value of Mapping the Language Network with MR Diffusion Tractography 100
Alberto Bizzi
Spinal Cord Imaging: Diffusion & Ultra-High Field 110
Julien Cohen-Adad
IT & Diffusion Imaging of the Cervical Spinal Cord 111
Eric E. Sigmund
Functional MR Imaging of the Spinal Cord 112
Patrick W. Stroman
Spinal Cord DTI: Applications to Multiple Sclerosis 113
DanielS. Reich
Clinical Spinal Cord Imaging: Connecting Emerging MRJ Technologies to Unmet Clinical Needs 114
Jonathan A. D. Farrell
Imaging Correlates of Spinal Cord Atrophy 115
GovindNair
Overview of the MRI System 117
Paul R. Harvey
MRJ Magnets - Design and Construction 118
Adrian Thomas
Siting the System 119
Stuart Clare
Shimming: Fields, Coils & Control 120
Christoph Juchem
Gradient Systems 126
Michaels. Poole
Field Monitoring & System Calibration 129
Christoph Barmet
Overview of Device Interactions 130
Gregor Schaefers
kHz (Gradient) Interactions 131
Blaine A. Chronik
Modeling Low Frequency Interactions 132
Stuart R. Crazier
MRI Transmitter Amplifier Systems 133
Greig C. Scott
Low Noise Amplifiers and Receive Chain Architectures for MRI Systems 134
Stephan Biber
MRI Console Electronics 135
Katsumi Kose
Quantum Mechanical Description ofNMR - From Wave Function to Bloch Equation 136
Michael H. Buonocore
Application of Quantum Mechanics & Statistical Mechanics: Equilibrium Magnetization, Relaxation & DensityMatrix 141
Adam W. Anderson
Practical Use of Multiple Quantum Coherences in Spectral Editing & 2D NMR 142
Robin A. De Graaf
From Bloch Equation to MR contrasts: Relaxation & Physical Bases of Tissue Contrast 146
John C. Gore
Other Contrast: Polarization Transfer, Chemical Exchange & Magnetization Transfer 147
PennyAnne Gowland
Bloch Equation in the Rotating Frame, Multidimensional Excitation 149
V. Andrew Stenger
Bloch-Torrey Equation & Diffusion Imaging (DWI, DTI, q-Space Imaging) 150
Jennifer A. McNab
Maxwell Equations & EM Modeling 154
FrankEngelke, Armin Purea
Static Magnetic Field: From Magnetic Susceptibility to Magnetic Field (in)Homogeneity and Back 155
Jose P. MarquesThe Gradient System - Understanding Gradients from an EM Perspective: (Gradient Linearity, Eddy Currents,Maxwell Terms & Peripheral Nerve Stimulation) 159
FranzSchmitt
RF Field Generation, Coupling, Standing Wave Transmission 172
David O. Brunner
RF Field Generation: Bl Field Non-Uniformity & SAR 173
Brian K. Rtttt
Bl-Shimming & Parallel Transmission 174
Ulrich Katscher
The Reciprocity Principle in NMR Reception 175
James TroppThe BOLD Effect & Its Use for Detecting Brain Activity 179
Clarisse I. Mark
Acquisition, Reconstruction & Artefacts 183
Hans Hoogduin
Data Analysis Basics 185
Robert L. Barry
fMRI in Basic & Clinical Neuroscience 186
Beau M. Ances
Neurovascular Coupling & Quantitation 187
Anna Devor
fMRI: From Basic to Intermediate Brain Connectivity. Pushing Temporal & Spatial Resolution 188
Pierre Levan
Optical Measurements in Functional Neuroimaging 189
Joseph P. Culver
Data Mash-Up: ERPs, EEG/MEG & Neurochemistry 190
Matthew J. Brookes
From Diffusion Weighting to the Diffusion Tensor Indices 191
GarethJ. Barker
Advanced Models - Ball & Stick, Multi-Tensor, PASMRI & Etc 192
Noam Shemesh
q-Space & Microstructure 196
Yaniv Assaf
Single Subject Diffusion Analysis - ROI, Histogram, Tractography 197
Mara Cercignani
Distortion Correction & Registration 198
Philip Cook, James Gee
Group Studies of Diffusion Data - Cross Sectional & Longitudinal Challenges 201
Stephen M. Smith
Basic Relaxation Mechanisms & Contrast Agent Design 202A. Dean Sherry
Agent Synthesis and Functionalization: From Small Molecules to Nanoparticles 204
Hut Mao
Switching & Sensing: The Design and Application of Responsive MRI Contrast Agents for Molecular Imaging 205
Mark D. Paget
Targeting Agents 207
David P. Cormode
Toxicity 208Erik M. Shapiro
Theranostic Probes for siRNA & MicroRNA Therapies 209Anna V. Moore
Technical Challenges to Detection 210
Peter M. Jakob
Applications: Translational Challenges and Opportunities for Molecular MR Imaging 211
ChristopherC. Quarles
Cell Delivery 212
JeffW. M. Bultc. AravindArepally
Specialty Area: Molecular & Cellular Imaging: From Bench to the Bed 213
Zahi A. Fayad
Rising PSA: Is There A Cancer? 218
Jurgen J. Fiitterer
Cirrhotic Liver: What Is That Nodule? 220Claude B. Sirlin
Characterization ofCystic Abdominal Lesions 221
Jay P. Heiken
Liver Lesions in Cancer Patients: What Are They? 222
Jeong Min Lee
Incidental Adnexal Masses in Cancer Patients: Act, Ignore or Follow? 225
Elizabeth A. Sadowski
Breast Cancer Response to NAC: How Reliable Is It? 226
Nolo M. Hyllon
Bone Metastases Response to Therapy: MRI Versus Nuclear Medicine 228Christina Messiou
Measuring Response to Novel Therapies: Thinking Differently 229Mark Rosen
Rising PSA in the Treated Prostate Gland 231
Aytekin Oto
Pain in the Treated Pelvis 232
Yuliya Lakhman
The Role of Biological MR Imaging in the Treatment of Head & Neck Cancer 233Sitresh Mukherji
New Developments in MR Hardware 236Boris R. Keil
New Sequences & Techniques 238
Krishna S. NayakParallel Acquisition & Compressed Sensing 239
Sebastian Ko2erke
The Evaluation of Cardiac Function - Unmet Needs 245Dara L. Kraitchman
Techniques to Image Cardiac Function 246Alistair A. Young
Research Promises: What Can We Expect in the Future? 247
Nael F. Osman
Technical Foundations: How is It Done? 249Michael Jerosch-Herold
Research Promises: What Can We Expect in the Future? 254
Craig H. Meyer
Clinical Needs: What Do We Want to See? 258
David E. Sosnovik
Technical Foundations: How is It Done? - Simonetti 260Orlando P. Simonetti
Research Promises: What Can We Expect in the Future? 264Gustav J. Strijkers
Clinical Needs: What Do We Want to See? 267MichaelD. Hope
Technical Foundations: How is It Done? 297Jos J. M. Westenberg
Research Promises: What Can We Expect in the Future? 299Oliver Wieben
Non-Contrast-Enhanced MRA 300Vivian S. Lee
Not So Fast: Recent Advances in CE-MRA 307Vlrike I. Attenberger
Best of Both Worlds 309
Jeffrey H. Maki
The Value of CMR Over Other Modalities in Clinical Trials 310Chun Yuan
Prognostic Value of CMR Versus Traditional Risk Factors 312DavidA. Bluemke, AdityaJain
Fluorine-19 318Shelton D. Caruthers
Carbon-13 Imaging in the Heart 319Charles H. Cunningham
Recent Innovations in Cardiac MR: MR-PET 321
Timothy G. Reese
PET-Instrumentation 101 322William W. Moses
Tracer 101 323Frederick T. Chin
PET-MR Hardware 101 324
Craig Levin
PET-MR in Drug Research 325Alexander J. S. De Crespigny
PET-MR in Oncology 326Nina F. Schwenzer
PET-MR in Neuro 327
Ciprian Calana
Body PET-MR 328Alexander S. R. Guimaraes
Cardio-Pulmonary MR-PET 331Ron Blankslein
Diffusion MRI in the Heart 332Choukri Mekkaoui
Skeletal Muscle 334John S. Thornton
Abdomen/Pelvis 338Thomas L. Chenevert
Breast 340Savannah C. Par/ridge
Spinal Cord/Nerve Roots 342
Jurgen Finsterbusch
Intervertebral Discs/Cartilage 343Jose Maria G. Raya
Post Mortem Brain 344Tim B. Dyrby
2D versus 3D Acquisition Strategies 345
Stefan Skare
Developmental Neuroanatomy 348OritA. Glenn
In Part from "Magnetic Resonance Imaging's Role in the Care of the Infant at Risk for Brain Injury" 349Petra S. Hiippi, Gregory A. Lodygensky, Caroline Menache
Neuroimaging ofNeonatal Seizures 372
Thierry A. G. M. Huisman
CNS Infections 373
Niranjan Khandelwal
Pediatric Inflammatory Disorders 375Ashok Panigrahy
Pediatric Neuroimaging in Metabolic Disorders 376C. C. Tchoyoson Lim
From CSF Pulsation to MR Measurement of ICP: Methodology & Potential Applications 377
Noam Alperin
CSF Physiology & Its Relationship to ICP 378
MarkE. Wagshul
Beyond 4D MRA 381
Patrick A. Turski
Normal Pressure Hydrocephalus 383
William G. Bradley Jr.
Geriatric Neuroimaging: White Matter Diseases of Aging 384
Maria A. Rocca
Differential Diagnosis of Neurodegenerative Disorders 388
Marco EssigCircuit & Transmission Lines 390
Scott B. KingVolume & Surface Coils 391
Ed B. BoskampMulti-Tuned Coils 392
Dennis W. J. Klomp, Peter R. Luiten
Receive Arrays 395
Steven M. Wright
Transmit Arrays 396
Mark E. Ladd
RF Modeling 397
Astrid L. H. M. Van Lier
Cavity Resonators - Theory & Possibilities for MRI 398
Andrew G Webb
Asymmetric Coils & Travelling Waves 404
Nicola F. De Zanche
Construction ofRX Arrays 407
Boris R. Keil
RF Pulses Designs: From Basics to the State-of-the-Art 417
Adam B. Kerr
Gradients: What Can They Do? 418
Chen Lin
Dealing with Motion: Gating, Triggering & Sampling 419
Christopher J. Hardy
Pulse Sequence Modules I (IR, DE, Spatial SAT & Chem SAT) 420
Graeme C. McKinnon
Pulse Sequence Modules II (Tagging, Labeling, Diffusion Sensitization & MT) 421
Eric C. WongFlow Contrast without Using Exogenous Agent 426
Yiping P. Du
Echo-Train Pulse Sequences: EPI, RARE & Beyond 428
David C. Alsop
Non-Cartesian k-Space Sampling 429
James G. Pipe
Spoiled & Balanced Gradient-Echo Sequences 430
Klaus Scheffler
Excitation k-Space and uTE MRI 434
John M. PolityParallel Image Reconstruction 435
Mark A. Griswold
Phase-sensitive Image Reconstruction 436
Qing-San Xiang
MR Safety: Where Do the Risks Come From? 438
Harold Kugel
Planning an MR Suite: What Can Be Done To Ensure MR Safety? 440
EmanuelKanal
Screening the Patient: How to Deal with the Individual Subject 444Anne Marie Sawyer
High Field MRI: What Are the Special Safety Risks at Higher Fields? 451
Richard W. Bowtell
Contrast Agent Use in the Age of NSF 453
Henrik Michaely
MR Safety Testing of Devices: How to Separate the Good From the Bad & the Ugly 454
Roger LuechingerMRI Safety Events: Lessons Learned 455
Robert E. Watson
Task-Less fMRI: The Phenomenon of Intrinsic Signal Fluctuations 456
Catherine E. Chang
Connectomics: Panellation & Network Analysis Methods 457
Gael VaroqitatLXDiseases ofConnectivity 459
Fruncioso Xavier Caslellanos
Connectivity Studies in Large Populations: Towards Defining Disease Mechanisms & Risk 460Paul M. Matthews
Current Limitations, Pitfalls & Criticisms 461
Gael Varoquaux
0001. Surface Coils N/A
Joseph J. H. Ackerman
0002. Inversion Recovery & Early Contrast Studies in the Brain: A Brief History 463
Ian R. Young
0003. Contrast MR Angiography N/A
MartinR. Prince
0004. Excitation K-Space & uTE MRI 466
John M. Pauly0005. FSE (RARE, TSE,...) 467
Jiirgen K. Hennig
0006. Regional Mapping ofGas Uptake by Red Blood Cells and Tissue in the Human Lung Using HyperpolarizedXenon-129 MRI 468
Kun Qing, Kai Ruppert, Yun Jiang, Jaime F. Mata, G Wilson Miller, Yun MichaelShim, Chengbo Wang, lulian C. Ruset, F.
William Hersman, Talissa A. Altes, John P. Mugler
0007. Dynamic Imaging ofthe Fetal Heart Using Metric Optimized Gating 469
Christopher W. Roy, Mike Seed, JoshuaF. P. Van Amerom, Bahiyah At Nqfisi, Lars Grosse-Wortmann, Shi-Joon Yoo, ChristopherK. Macgowan
0008.3D Hemodynamics in Intracranial Aneurysms: Influence of Size and Morphology 470
SusanneSchnell, Sameer A. Ansari, Parmede Vakil, Marie Wasilewski, Maria L. Carr, Michael C Hurley, Bernard R. Bendok,Hunt Batjer, Timothy J. Carroll, James C. Carr, Michael Markl
0009. Multi-Slice Cardiac Arterial Spin Labelling Using Improved Myocardial Perfusion Quantification with
Simultaneously Measured Blood Pool Input Function 471
Adrienne E. Campbell-Washburn, Hui Zhang, Bernard M. Siow. Anthony N. Price, MarkF. Lythgoe, Roger J. Ordidge, David L.
Thomas
0010. Joint K-T Reconstruction and Oversampled Spirals for Single-Shot 2D Spatial/1D Spectral Imaging of l5CDynamics 472
Jeremy W. Gordon, David J. Niles, Sean B. Fain, Kevin M. Johnson
0011. A New Approach to Shimming: The Dynamically Controlled Adaptive Current Network 473
Chad Tyler Harris, William B. Handler, Blaine A. Chronik
0012. Reduced-FOV Imaging with Excitation Using Nonlinear Gradient Magnetic Fields (ENiGMa) 474
Emre Kopanoglu, Ergin Atalar, Robert ToddConstable
0013. Ultrafast Single Shot Imaging with Rotating Nonlinear Fields 475
Gigi Galiana, Robert Todd Constable
0014. A 3-Axis Phase Gradient Array for RF Encoded MRI Using the TRASE Method 476
Jonathan C. Sharp, Qunli Deng, Scott B. King, Vyacheslav Volotovskyy, Boguslaw Tomanek
0015. Shear Wave Imaging by Using Bi Gradients 477
Esra Turk, YusufZiyaIder, ArifSanli Ergun, TanerDemir, Ergin Atalar
0016. 3D Imaging with Multidimensional Nonlinear Encoding 478
Maxim Zaitsev, Sebastian Littin, Anna M. Welz, FengJia, Chris A. Cocosco, Andre*' Dewdney. Gerrit Schuttz. Jiirgen Hennig
0017. MRI by Steering Resonance Through Space 479
AngelaLynn Styczynski Snyder, Curtis Andrew Corum, Steen Moeller, Nathaniel J. Powell, Michael Garwood
0018. MR Fingerprinting: Rapid Simultaneous Quantification ofTl, T2, Proton Density and Off-Resonance Usinga Spiral Trajectory 480
Dan Ma, Vikas Gulani, Nicole Seiberlich, Jeffrey Duerk, Mark A. Griswold
0019. MR Fingerprinting Using Spiral QUEST 481
YunJiang, Dan Ma, Renate Jerecic, Vikas Gulani, Nicole Seiberlich, Jeffrey Durek, Mark A. Griswold
0020. Overhauser Enhanced MR Elastography at Very Low Field 482
Najat Satameh, MathieuSarracanie, Brandon Dean Armstrong, ArnaudComment, Matthew S. Rosen
0021. Driver-Free Assessment ofLiver Stiffness Using Fast Strain-Encoded (FSENC) MRI 483
AhmedA. Harouni, Ahmed M. Gharib, Nael F. Osman. Roderic I. Pettigrew, KhaledZ. Abd-Elmoniem
0022. Renal Diffusion and Perfusion in Cardiorenal Syndrome 484
Nur Farhayu Omar, Eleanor F. Cox, Tobias Breidthardt. fain B. Squire. Aghogho Odudu, Mohamed Torek Eldehni, Chris
Mclntyre, Susan T. Francis
0023. Susceptibility Tensor Imaging of the Renal Tubule 485
Luke Xie, Russell Dibb, Wei Li, Chunlei Liu, G. Allan Johnson
0024. Changes in Intrarenal Oxygenation as Evaluated by BOLD MRI in a Rat Biliary Obstruction Model 486
Mingshu Yang, Minji, Bin Yang, Li Wang, Chunmei Xia, Lixia Yang, Zhongwei Qiao, EdX. Wu
0025. Effects of an X-Ray Contrast Medium Administration on Renal T2* and T2 487
Andreas Pohlmann, Karen Arakelyan, Kathleen Cantow, Jan Hentschel, Bert Flemming. MechthildLadwig, Erdmann Seeliger,Thoralf Niendorf
0026. Evaluation ofNephrotoxicity of Iso- Versus Low-Osmolar Iodine Contrast Media by BOLD and Diffusion-
Weighted MR Imaging 488
Yuan-Cheng Wang, Shenghong Ju. Gao-Jun Teng
0027. High Temporal Resolution Mouse Renal Blood Flow (RBF) Imaging with Pseudo-Continuous ASL (PCASL)at Very High Field 489
Guillaume Duhamel, Valentin Prevost, Olivier M. Girard, Virginie Callot, Patrick J. Cozzone
0028. Assessment of Experimental Acute Kidney Injury by Fast Interleaved Monitoring ofT2* and T2 490
Andreas Pohlmann, Jan Hentschel. Mandy Fechner, Uwe Hoff Gordana Bubalo. Karen Arakelyan, Kathleen Canlow, Erdmann
Seeliger. Bert Ftemming, Lajos Marko, Helmar Waiczies, Sonia Waiczies, WolfHagen Schunck, DominikN. Mueller, Duska
Dragun, ThoralfNiendorf
0029. Combination of Non-Invasive Parametric MRI and Invasive Physiological Measurements: Towards a
Hybrid and Integrated Approach for Investigation ofAcute Kidney Injury 491
Jan Hentschel, Kathleen Cantow, Andreas Pohlmann, Karen Arakelyan, Bert Flemming, Mechthild Ladwig, Erdmann Seeliger,Uwe Hoff, Pontus B. Persson, Thoralf Niendorf
0030. Feasibility of Single Breath-Hold Renal Perfusion Imaging at 7T 492
Xiufeng Li, Carl Snyder, Pierre-Francois VanDe Moortele. Kamil Ugurbil, Gregory J. Metzger
0031. Arterial Spin Labeling for Quantification and Monitoring of Renal Blood Flow Changes After Acute Kidney
Injury in Mice - Comparison with Histopathology and Renal Function 493
Katja Hueper, Marcel Gutberlet, DagmarHartung, Song Rong, Hermann Holier, Martin Meier, Frank Wacker, Faikah Gueler
0032. Anatomical/Axonal Basis and Plasticity of Resting-State fMRI Connectivity in an Experimental Model of
Corpus Callosum Transection 494
Iris Y. Zhou, Y. X. Liang. Russell W. Chan, Shujuan Fan. Patrick P. Gao. Joe S. Cheng, K. F. So, EdX. Wu
0033. Caffeine-Induced Reductions in the Resting-State fMRI Global Signal Reflect Increases in EEG VigilanceMeasures 495
Chi Wah Wong, Valur Olafsson, Omer Tal, Thomas Liu
0034. Clustered Spontaneous Coordinated Network Events Contribute to Functional Connectivity 496
Thomas Allan, Matthew J. Brookes, Susan T. Francis, Penelope A. Gowland
0035. Multiple Time Scale Complexity Analysis of Resting State Fluctuations 497
Robert Smith
0036. Finite Number of Brain Network Configurations Revealed from Time-Varying Connectivity Assessment of
Resting State fMRI 498
Hao Jia, Xiaoping P. Hu, Gopikrishna Deshpande
0037. Investigation of the Neural Basis of the Default Mode Network Using Parallel Independent ComponentAnalysis ofSimultaneous EEG/fMRI Data 499
Sreenath Pntthviraj Kyathanahally, Nurhan Erbil, Vince D. Calhoun, Gopikrishna Deshpande
0038. Intrinsic Connectivity Network Activity Revealed by the Independent Modelling of the Primary and Post-
Stimulus Components of the BOLD Response 500
Karen J. Mullinger, Stephen D. Mayhew, Andrew P. Bagshaw, Richard W. Bowtell, Susan T. Francis
0039. Spontaneous Co-Activation Patterns ofthe Brain Revealed by Selectively Averaging Resting-State fMRI
Volumes 501
Xiao Liu, Catie Chang. Jeff H. Duyn
0040. Resting Brain Networks Revealed by Independent Component Analysis of Cerebral Blood Flow 502
Senhua Zhu, Zhuo Fang, Siyuan Hit, MarcKorczykowski, Ze Wang, John A. Detre, Hengyi Rao
0041. Resting-State fMRI at 4 Hz 503
Ying-Hua Chu, Jyrki Ahveninen, Tommi Raij, Wen-Jui Kuo, John W. Belliveau, Fa-Hsuan Lin
0042. Functional and Structural Disruption of the Precuneus Contributes to Cognitive Impairment in Pediatric
Multiple Sclerosis 504
Maria A. Rocca, Martina Absinta, Maria Pia Amato, Angelo Ghezzi, Lucia Moiola, Agnese Fiorino, Pierangelo Veggiotti,Giancarlo Comi, Massimo Filipp
0043. Impaired Regulation of the Blood Supply to the Brain in Multiple Sclerosis Measured with HypercapniaBOLD MRI 505
Yulin Ge, Hanzhang Lu, Yongxia Zhou, FengXu, IlyaKister, HinaJaggi, JosephHerbert, Robert I. Grossman
0044. Regional Hippocampal Involvement Differs Across Multiple Sclerosis Clinical Phenotypes: A Radial
Mapping MRBased Study 506
Elisabetta Pagani, Maria A. Rocca, Giulia Longoni, Vittorio Martinelli, Bruno Colombo, Andrea Falini, Giancarlo Comi, Massimo
Filippi0045. Macromolecular Proton Fraction as a New Clinical Biomarker of Demyelination in Multiple Sclerosis 507
Vasily L. Yarnykh, James D. Bowen, Alexey A. Samsonov. Pavle Repovic, AngeliMayadev, Bart P. Keogh, Beena Gangadharan,HunterR. Underbill, Kenneth R. Maravilla, Lily K. Jung Henson
0046. Spatial Patterns ofCortical Thinning in Neuromyelitis Optica: A Comparative Study with Multiple Sclerosis 508
Yaou Liu, Teng Xie, Ni Shu, Kuncheng Li, Yong He
0047. Hippocampal Magnetization Transfer Ratio and Not Hippocampal Atrophy Best Explains Memory
Dysfunction in Patients with Multiple Sclerosis 509
Mishkin Derakhshan, Gabriel Leonard, Daviad Araujo, D. Louis Collins, Douglas L. Arnold, Sridar Narayanan
0048. Regional Cortical Thickness in Relapsing Remitting Multiple Sclerosis: A Multi-Center Study 510
Ponnada A. Narayana, Koushik Govindarajan, Priya Gael, Sushmita Datta, John A. Lincoln, Stacy S. Cofteld, Gary R. Cutter, Fred
D. Lublin, Jerry S. Wolinsky
0049. Magnetisation Transfer Imaging of Subpial Cortical Abnormalities in Multiple Sclerosis 511
Rebecca S. Samson, Manuel Jorge Cardoso, Nils Muhlert, Varun Sethi, Claudia Angela M. Wheeler-Kingshott, Maria A. Ron,
Sebastian Ourselin, DavidH. Miller. Declan T. Chard
0050. Impact of Macrophagic Activity on Tissue Structure in Patients Suffering from Clinically Isolated Syndrome
Suggestive of Multiple Sclerosis: A Multicentric USPIO Enhancement Study at 3T 512
Adil Maarouf Jean Chrislophe Ferre. Wafaa Zaaraoui, Elise Bannier, Christian Barillot, Isabelle Berry, Gilles Edan, Damien
Galanaud, Jean Pelletier, Chrislophe Portefaix, Ayman Tourbah, Jean-Philippe Ranjava, Bertrand Audoin
0051. Correlations Between Corpus Callosal Myelin Water Fraction and Measures ofTranscallosal Inhibition in
Multiple Sclerosis Patients on Glatiramer Acetate Treatment 513Eric Y. Zhao. Irene Vavasour. Marjan Zakeri, Michael Borich. Cornelia Laule. Anthony L. Traboulsee. David K. B. Li. Lara Boyd,Alex L. Mackay
0052. The Human Connectome Project: Advances in Diffusion MRI Acquisition and Preprocessing 314Stamatios N. Sotiropoulos, Saad Jbabdi, JunqianXu. Jesper L. Andersson. Sleen Moeller, Edward J. Auerbach. Mat/hew F.
Glasser, DavidFeinberg, Christophe Lenglet. David C. Van Essen. Kamil Ugurbil, Timothy E. J. Behrens, Essa S. Yacoub
0053. Combining ZOOPPA and Blipped CAIPIRINHA for Highly Accelerated Diffusion Weighted Imaging at 7T
and 3T 515
Cornelius Eichner, Kawin Setsompop, Peter J. Koopmans, Alfred Anwander, RalfLutzkendorf, Steven F. Cauley, Himanshu Bhal.
David G. Norris, Robert Turner. Lawrence L. Wald, Robin Martin Heidemann
0054. 3D Multi-Slab Diffusion-Weighted Readout-Segmented Echo-Planar Imaging with Real-Time Cardiac-
Reordered K-Space Acquisition 516
Robert Frost, KarlaL. Miller, DavidA. Porter. Rob H. N. Tijssen, Peter Jezzard
0055. Accelerating Data Acquisition for Reversed-Gradient Distortion Correction in Diffusion MRI: A
Constrained Reconstruction Approach 517
Chilresh Bhushan, AnandA. Joshi, Richard M. Leahy. Justin P. Haldar
0056. High-Resolution Diffusion Weighted MRI Enabled by Multi-Shot EPI with Multiplexed Sensitivity-Encoding 518Nan-Kuei Chen, Arnaud Guidon, Hing-Chiu Chang, Allen W. Song
0057. Tilted 2D RF Excitation with Extended Slice Coverage for High-Resolution Reduced-FOV DWI 519Suchandrima Banerjee, Emine U. Saritas, GerdMelkus, Ajit Shankaranarayanan
0058. Fast DSI Reconstruction with Trained Dictionaries 520Berkin Bilgic, Itthi Chatnuntawech, Kawin Setsompop, Stephen F. Cauley, Lawrence L. Wald, Elfar Adalsteinsson
0059. Optimal Acquisition Protocol for White Matter Fiber Orientation Mapping Using Generalized CSA-ODF
Reconstruction 521Amith J. Kamath, /man Aganj, Junqian Xu, Essa S. Yacoub, Kamil Ugurbil, Guillermo Sapiro, ChristopheLenglet
0060. A Comparison Between Double-PFG MRI and DTI in ex Vivo Rat Brain 522Tuukka Miettinen, Alejandro Sierra, Teemu Laitinen, Juhana Sorvari, Olli Grohn
0061. Oscillating Gradient Spin-Echo (OGSE) Diffusion Tensor Imaging ofthe Human Brain 523
CoreyAllan Baron, Christian Beaulieu
The Physics ofMRI - Basic Spin Gymnastics 524
Walter Kucharczyk, Donald B. Plewes
K-Space 536Kevin M. Koch
Shoulder: Sources of Impingement 538Michael P. Recht
Hip: Femoral-Acetabular & Ischiofemoral Impingement 539Julia Crim
MRI ofAnkle Impingement Syndromes 541
James M. Linklater
Nerve Impingement Around the Body 542
Luis S. Beltran
Surgical Perspective: Neurosurgical Approach to Brain Tumors 543
Randy L. Jensen
The Perspective ofthe Neuro-oncologist in Brain Tumor Management after Surgery: What are the Questions &How can MR ImagingHelp? 544
Howard Colman
Addressing the Oncologist's Concerns with MR Imaging: Now & Future 545
Whitney Pope
0062. A Direct Calculation of Hemodynamic Energy Loss in the Presence of Abnormal Aortic Flow 546
Alex J. Barker, Krishna C. Bandi, Julio Garcia. Pirn Van Ooij, Patrick McCarthy. James C. Carr, S Chris Malaisrie, Michael
Mark!
0063.4D Flow MRI for Non-Invasive Assessment ofMesenteric Ischemia 547
Oliver Wieben. Alejandro Roldan-Alzate. Scott B. Reeder, Mark L. Schiebler. Scott K. Nagle, Charles W. Acher, Ben Ray Landgraf.Thomas M. Grist. Christopher J. Francois
0064. New Insights in the Disagreement ofTransvalvular Mean Pressure Gradient Measured by Transthoracic
Echo-Doppler and Cardiovascular Magnetic Resonance in Patients with Aortic Stenosis 548
Julio Garcia, Romain Capoulade, Lyes Kadem, Eric Larose, Philippe Pibarot
0065. Evaluation and Validation of Pulse Wave Velocity Measurements from 2D and 4D PC MRI in Swine with
Familial Hypercholesterolemia: Initial Results 549
Andrew L. Went/and, Thomas M. Grist, Dhanansayan Shanmuganayagam, Christian G. Kmeger, Patrick E. McBride, Jennifer J.
Meudt. Jess D. Reed, Oliver Wieben
0066. High Temporal-Resolution Three-Directional Velocity Measurements in a Single Breath-Hold Using EPIand Direct Inversion 550
NingJin, Rizwan Ahmad, Yu Ding, Sven Zuehlsdorff, Orlando P. Simonetti
0067. 4D UTE Flow: A Novel 4D Ultra-Short TE Phase-Contrast MRI Technique for Assessment of Flow and
Hemodynamics 551
Mo Kadbi. Melanie S. Traughber, Peter Martin, AmirA. Amini
0068. High-Resolution, High-SNR Velocity Maps Reconstructed from Low-Resolution Fourier Velocity EncodedMRI Data 552
Vinicius De Carvalho Rispoli, Joao L. A. Carvalho
0069. Analysis ofThermal Stability of Background Phase Errors in Phase-Contrast Flow Imaging 553
Julia Busch, Signe Johanna Vannesjo, Chrisloph Barmel, Klaus P. Pruessmann, Sebastian Kozerke
0070. 4 Dimensional, Single Step Laplacian Algorithm for Phase Unwrapping in 4D MR Flow 554
MichaelLoecher, Oliver Wieben, Kevin M. Johnson
0071. Improved Excitation Fidelity in Cardiac Imaging with 2-Spoke Parallel Excitation at 7 Tesla 555
Sebastian Schmitler, Lance Delabarre, Xiaoping Wu, Andreas Creiser, Dingxin Wang, Kami! Ugurbil, Pierre-Francois Van De
Moortele
0072. Improvement in B1+ Homogeneity of3T Cardiac MRI in Swine with Dual-Source Parallel RF Excitation 556
Daniel A. Herzka, Haiyan Ding, Michael Schar
0073. kT - PINS RF Pulses for Low-Power Field Inhomogeneity-Compensated Multislice Excitation 557
Amy Sharma, Samantha J. Holdsworth, Rafael O'Halloran, Eric Aboussouan, Anh Tu Van, Julian R. Maclaren, Mural Aksoy,Victor Andrew Stenger, Roland Bammer, William A. Grissom
0074. Simultaneous Multi-Slice Parallel RF Excitation with In-Plane B1+ Homogenization 558
Xiaoping Wu, Sebastian Schmitler, Edward J. Auerbach, Sleen Moeller, Kamil Ugurbil, Pierre-Francois Van De Moortele
0075. Simultaneous Multi-Slice Excitation by Parallel Transmission Using a Dual-Row PTX Head Array 559
Benedikt A. Poser, Robert James Anderson, Peter Serano, Azma Mareyam, Bastien Guerin, WeiranDeng, Lawrence L. Wald,
Victor Andrew Stenger
0076. Subject- And Resource-Specific Monitoring and Proactive Management of Parallel RF Transmission 560
Cem Murat Deniz, LeeorAlon, Ryan Brown, DanielK. Sodickson, Yudong Zhu
0077. Improvement in T2-Weighted Imaging at 7T by Using K[-Points 561
Florent Eggenschwiler, Kieran O'Brien, Rolf Gruetter, Jose P. Marques
0078. Fast Reconstruction for RF Monitored Sweep Imaging with Sideband Excitation 562
David Otto Brunner, Benjamin E. Dietrich, Matteo Pavan, Klaas P. Pruessmann
0079. B|-Insensitive Slice-Selective Pseudo-Adiabatic Pulse 563
Benoit Bourassa-Moreau, Guillaume Gilbert, Gilles Beaudoin
0080. A Simple Fat Suppression Method for Accelerated and Low-SAR 3D-EPI 564
Riidiger Stirnberg, DanielBrenner, Tony Stocker, Nadim Jon Shah
0081. Multiparametric Microvascular MRI: A Cluster Approach to Characterize Glioma 565
Nicolas Coquery, Clement S. Debacker, Regine Farion, Chantal Remy. Olivier Francois, Emmanuel Luc Barbier
0082. Longitudinal Characterization ofApolipoprotein E Targeted Replacement Mice at 7 T 566
James A. Goodman, Peter Cheng-Te Chou, Zhiyong Xie, Kelly R. Bales
0083. Microscopic 3D-DTI ofTumor Cell Migration, Numerical Modeling and Two- Photon Microscopic Imaging 567
Ulysse Gimenez, Florence Appaix, Teodora-Adriana Perles-Barbacaru, Franck Mauconduit, Marie-France Nissou, Emilie
Langard, Laurent Pelletier, Francois Berger, Didier Wion, Boudewijn Van Der Sanden, ffana Lahrech
0084. Preclinical MRI Reveals Bevacizumab Mitigates Radiation Necrosis 56S
X. Jiang, John A. Engelbach, Jeremy Cates, Dinesh K. Thotala, R. E. Drzymala, D. E. Hallahan, J. H. Ackerman, Joel R. Garbow
0085. Effects ofMaternal Chlorpyrifos Exposure on Guinea Pig Neurodevelopment 569
Roger J. Mullins, Su Xu, Joseph D. Pescrille, Jacek Mamczarz, Edna Pereira, EdsonX. Albuquerque, Rao P. Gullapalli
0086. Multivoxel Proton MR Spectroscopy Reveals Subcortical Glial Response to SIV-Infection in Rhesus
Macaques 570
William E. Wu, Ke Zhang, AssafTal, Eva-Maria Ratai, Ramon Gilberto Gonzalez, OdedGonen
0087. Activity-Modulated Interhemispheric Manganese Transfer Upon Intracortical Injection 571
Shu-Juan J. Fan, Wenwen A. Han, Frank Y. Lee, Kevin C. Chan. Samantha J. Ma, EdX. Wu
0088. Decreased Functional Connectivity After Acute Cocaine Administration: A Feasibility Study ofResting-State fMRI in Awake Non-Human Primates 572
Kaundinya Gopinath, Kevin Murnane, Leonard Howell
0089. Gd-Staining Reveals the Efficacy of an Anti-AB Antibody to Decrease Amyloid Plaque Load in Vivo in a
Transgenic Mouse Model of Alzheimer's Disease 573
Mathieu DavidSantin, Thomas Debeir, Thierry Delzescaux. Anne-Sophie Herard, Caroline Cohen, Laurent Pradier, Thomas
Rooney, MarcDhenain
0090. The Dose Response of the Developing Mouse Brain After Cranial Irradiation Varies by Brain Structure 574
Lisa M. Gazdzinski. RichardJ. Alsop, Brian J. Nieman
0091. MRI-US Fused Targeted Prostate Biopsy Detects Clinically Significant Cancer in Active Surveillance
Patients Better Than 12 Core Random Biopsy with Less Than 4 Cores 575
Michael Da Rosa, Laurent Milot, Linda Sugar, Danny Vesprini, Hans Chung, Andrew Loblaw, Laurence Klotz, Masoom A. Haider
0092. Validation Study ofESUR Prostate MR Guidelines 2012: The Significance of Different Sequences of Multi-
Parameter MRI in Detection ofProstate Cancer in 106 Consecutive Patients 576
Juan Hu, He Wang, Xuedong Yang, Chengyan Wang, Rui Wang, Ge Gao, Hui Zhang, Wenchao Cai, Wei Wang, Jue Zhang,Xiaoying Wang
0093. Derivation and Comparison of Site Specific Peripheral and Transition Zone Quantitative DCE MRI LogisticRegression Models for Prostate Cancer Detection: Does Cancer Location Matter? 577
Nikolaos Dikaios. MohamedAbdAlazeez, MarkEmberton, Taiki Fujiwara, David Atkinson, Shonit Punwani
0094. Computed Diffusion-Weighted Imaging of the Prostate at3T: Impact on Image Quality and Tumor
Detection 578
Andrew B. Rosenkrantz, Nicole Hindman, Hersh Chandarana, Fang-Ming Deng, James S. Babb, Samir S. Taneja, Christian
Geppert0095. Contrast Dispersion Mapping in DCE MRI: A New Option for Prostate Cancer Detection 579
Massimo Mischi, Kyveli Kompatsiari, Tamerlan Saidov. Marc Engelbrecht, Hessel Wijkstra, Marcel Breeuwer
0096. Hybrid T2 and Diffusion Weighted MRI for Prostate Cancer Detection 580
Shiyang Wang. Yahui Peng, Milica Medved, Ambereen Yousuf. Marko Ivancevic. Ibrahim Karademir, Yulei Jiang, Tatjana Antic.
Steffen Sammel. Aytek Oto, Gregory S. Karczmar
0097. 'H MRSI of Prostate Cancer Incorporating Spermine in the Quantification, a 7 Tesla Patient Study 581
Mariska P. Lultje, Robin A. De Graaf, Catalina S. ArleagaDe Castro, Peter R. Luijlen, Marco Van Vulpen, Uulke A. Van Der
Heide, Dennis W. J. Klomp0098. Stratification of Disease Aggressiveness of Prostate Cancer Using MRSI and DWI 582
Durgesh KumarDwivedi, GirdharBora, Rajeev Kumar, Sanjay Thitlkar, Sanjay Sharma, Siddhartha D. Gupta, NaranamangalamR. Jagannathan
0099. MR Spectroscopic Imaging of Prostate Cancer: Metabolism or Morphology? 583Thiele Kobus, Jeroen Van Der Laak, Caroline Bruggink, Christina Hulsbergen-Van DeKaa, Tom W. J. Scheenen, Arend
Heerschap
0100. Planning a Boosted Radiotherapy Dose to the Dominant Intraprostatic Tumour Lesion Within the Prostate
as Defined by Multifunctional MR Parameters 584
SophieF. Riches, Geoffrey S. Payne, Nandita M. Desouza. Scott Morgan. David Dearnaley, Veronica A. Morgan, SharonL. Giles,Mike Partridge
0101. Fast Cerebral Flow Territory Mapping Using Vessel Selective Dynamic Arterial Spin Labeling 585
Xingxing Zhang, Eidrees Ghariq, Sophie Schmid, Wouter M. Teeuwisse, Andrew G. Webb, Matthias J. P. Van Osch
0102. The Use of k-Means Clustering and Bayesian Inference Framework for the Processing ofVessel-Encoded P-
CASL Images as Compared with Super-Selective P-CASL MRI 586
Nolan S. Hartkamp, Michael Helle. MichaelA. Chappell, Thomas W. Okell, ReinoudP HBokkers, Jeroen Hendrikse, Matthias J.
P. Van Osch
0103. VENTI: Venous Territory Imaging Using Remote Sensing 587
Eric Wong, Jia Guo
0104. High Temporal Resolution Sampling ofTracer Kinetic Curves Using Time Encoded PCASL with Look-
Locker Readout 588
WouterM. Teeuwisse, Sophie Schmid, Andrew G. Webb, Matthias J. P. Van Osch
0105. Time Efficient Determination ofSpin Compartments by Time Encoded Arterial Spin Labeling 589
Sophie Schmid, Wouter M. Teeuwisse, Eidrees Ghariq, Andrew Webb, Hanzhang Lu, Matthias J. P. Van Osch
0106. Assessing Intracranial Vascular Compliance Using Dynamic Arterial Spin Labeling 590
Lirong Yan, Robert Smith, Collin Liu, Emily Kilroy, Yufen Chen, Danny J. J. Wang
0107. Simultaneous Acquisition of Cerebral Blood Volume, Blood Flow and Blood Oxygenation Weighted MRI
Signals at7T 591
Steffen N. Krieger, Laurentius Huber, Gary F. Egan, Robert Turner
0108. Multi-Bolus Pulsed ASL for Improved Renal Perfusion Quantification 592
Xiang He, Serter Gumus, Ayaz Aghayev, Kyongtae TyBae
0109. Simultaneous Arterial Spin Labelling MRI and H20ls Position Emission Tomography 593
Ke Zhang, HansHerzog, Christian Filss. Thomas Fischer, Walter Sturm. Burkhard Brocke, Nadim Jon Shah
0110. Investigating White Matter Perfusion Using Optimal Sampling Strategy Arterial Spin Labeling (OSS-ASL)at 7T 594
Alexander Graeme Gardener, Peter Jezzard
Methods for Hyperpolarizing Nuclear Spins 595
Jan H. Ardenkjaer-Larsen
Methods for Fast Imaging ofHyperpolarized Nuclei 597
Charles H. Cunningham
Preclinical Metabolic Imaging (Cancer, Cardiac, Kinetic Analysis) 599
DanielM. Spielman
Cardiovascular MR Imaging: Pushing the Limits, Part 1 600
Reza NezafatWhat's New in MR Safety?- Active Implants, Device Labeling & Identification 601
William Faulkner
Occupational Exposure Limits, Magnetic Field Spatial Gradients & Their Impact on MR Safety Practices 602
Gregory C. Brown
To Scan or Not to Scan? MR Safety Decision Making & the FPO Mode 604
EmanuelKanal, Anne Marie Sawyer
Legacy Implants, MR Conditional Labeling, Conflicting Information - MR Safety Now & the Future: Is There a
Better Paradigm? N/A
Stephanie Haaf
Genetics and Molecular Biology ofAlzheimer's Disease - Who Will Benefit from this Information 608
N/a
Quantitative Neuroimaging in the Clinical Setting: Toward an Earlier and More Accurate Diagnosis of
Neurogenerative Disease 613
James Brewer
Predicting Neurodegenerative Disease with Connectomics 614
Ashish Raj
0111. The C57BL/6 Mouse Exhibits Sporadic Congenital Portosystemic Shunts 615
Cristina Cudalbu, Valerie A. McLin, Hongxia Lei, Joao M. N. Duarte, Anne-Laure Rougemont. Graziano Oldani, Sylvain Terraz,
Christian Toso, RolfGruetter
0112. Astrocyte Reactivity Is Associated with Decreased Levels of N-Acetyl-Aspartate in the Absence of
Neurodegeneneration in the Rat Brain 616
Maria-Angeles Carrillo-De Sauvage, Lucile Ben Haim, Julien Valette. Carole Escartin
0113. 7 T 'H Detects Human Brain Gutamate Concentration Changes in Response to Hypoglycemia: A Study of
Diabetic Patients with and Without Hypoglycemia Unawareness 617
Melissa Terpstra. Amir Moheet, Anjali Kumar, Lynn E. Eberly, Elizabeth Seaquist, Gulin Oz
0114. Early Increases in Glu/GIn, Tau and TCho 1H MRS Resonances in vivo, Anticipate Later ImagingRepercussions ofthe Cerebral Inflammatory Response in a Mouse Model ofLPS-Induced Endotoxemia 618
Ana Belen Martin-Recuero, Agnieszka Krzyzanowska, Pilar Lopez-Larrubia, Carlos Avendaho, Sebastian Cerdan
0115. uNa-MRI and EPT: Are Sodium Concentration and Electrical Conductivity at 298 MHz (7T) Related? 619
Astrid L. H. M. W. Van Lier. Paul W. De Bruin, Sebastian A. Aussenhofer. Peter R. Luijten, Jan J. W. Lagendijk. Cornells A. T. Van
Den Berg, Andrew G. Webb
0116. Chlorine (35Cl) MRI in Humans: CI- Alterations Do Not Correspond to Disease-Related Na* Changes 620
Armin M. Nagel, Marc-Andre Weber, Frank Lehmann-Horn, Karin Jurkat-Rott, Alexander Radbruch, Reiner Umathum, WoljhardSemmler
0117. In Vivo Cardiac 'H MRS, 31P MRS, and MRI in Mouse Models of Increased Fatty Acid Oxidation with and
Without Myocardial Lipid Accumulation 621
Desiree Abdurrachim, Jolita Ciapaite, Michel Van Weeghel, Bart Wessels, Klaas Nicolay, SanderM. Houten, Jeanine J. Prompers0118. Caloric Restriction Enhances Oxidative Brain Metabolism in Healthy Aging Detected by 'H("CJMRS 622
Ai-Ling Lin, Daniel Coman, Lihong Jiang, Douglas L. Rothman, Fahmeed Hyder0119. Rates of Human Hepatic Oxidative Metabolism Estimated in Vivo Using a Novel "C-MRS Method 623
Douglas E. Befroy, Nimit Jain, Kill Folk Pelesen, Gerald I. Shulman, Douglas L. Rothman
0120. Acetylcarnitine Turnover in Rat Skeletal Muscle Measured in Vivo Using Localized "C NMR at 14.1 T 624
Jessica A. M. Bastiaansen, Joao M. N. Duarte, ArnaudComment, Rolf Gruetter
0121. Slab Profile Encoding for Minimizing Venetian Blind Artifact in 3D Diffusion-Weighted Multislab
Acquisition 625
Anh Tu Van, MuralAksoy, SamanthaJ. Holdsworth, DanielKopeinigg, Sjoerd 8. Vos, RolandBammer
0122. Accelerated Parallel Traveling Wave MR and Compressed Sensing Using a2-Channel Transceiver Array 626
Maryam Varelh, Anita Flynn, Wei Bian, Ye Li, DanielB. Vigneron, Sarah J. Nelson, Xiaaliang Zhang0123. Separation of Two Simultaneously Encoded Slices with a Single Coil 627
Daniel B. Rowe, Andrew S. Nencka. Andrzej Jesmanowicz, James S. Hyde0124. Local Resolution Adaptation for Curved Slice Imaging 628
Hans Weber. Gerril Schullz, Daniel Gallichan, Jiirgen Hennig, MaximZaitsev
0125. Simultaneous Multi-Slice Flyback Echo Planar Imaging with Auto-Calibration 629
Kangrong Zhu, AdamKerr, John M. Pauly
0126. Automated Selection of 2D-CAIPIRINHA Kernels and Application to 3D CE-MRA 630
Paul T. Weavers, Eric A, Borisch, Stephen J. Riederer
0127. ESPIRiT Reconstruction Using Soft SENSE 631Martin decker, Patrick Virtue, Shreyas S. Vasanawala. MichaelLustig
0128. Improving K-T Auto-Calibrating Parallel Imaging for 3D Cardiac Cine MRI Using Prior-Reconstruction
Static Tissue Estimation and Elimination 632
Peng Lai, Shreyas S. Vasanawala, Atsushi Nozaki, Maggie Fung. Anja C. SBrau
0129. Iterative Trajectory Correction for Radial Projection Imaging 633Tobias Wech, Johannes Tran-Gia, Dietbert Hahn, Herbert Kdstler
0130. Calibrationless Chemical Shift Encoded Imaging Using a Time-Segmented K-Space Reconstruction 634
Samir D. Sharma, Joshua D. Trzasko, Armando Manduca
0131. A Separated Transmit-Only, Receive-Only Array for Body Imaging at 7T with Automated Tuning and
Matching Capabilities 635
Carl Snyder. Lance Delabarre. Aaron T. Hess, Chris Rodgers, Mattew Robson, J. Thomas Vaughan0132. A Novel Flexible Flex Cable Antenna (FFCA) for Foot MR Imaging 636
Hongyang Yuan, Qunzhi Chen, Yu Wang, Wenchao Cat, Xiaoying Wang, Jue Zhang, JingFang0133. Screen Printed Flexible 2-Channel Receive Coil Array 637
Joseph R. Corea, AnaClaudia Arias, Anita Flynn, Greig C. Scott, Peter Shin, MichaelLustig
0134. Development of a Catheter-Mounted Cardiac RF Coil for Temperature Imaging in Atrial Fibrillation
Treatment 638
Nelly A. Volland. Robb Merrill. J. Rock Hadley. Dennis L. Parker
0135. High-Temperature Superconducting Radiofrequency Probe for MRI Applications Operated Below AmbientPressure in a Simple Liquid-Nitrogen Cryostat 639
Simon Auguste Lambert, MariePoirier-Quinol, Jean-Chrislophe Ginefri, Luc Darrasse
0136. MR Microimaging Using a High Tc Superconducting Bulk Magnet with Compressed Sensing 640Daiki Tamada, Takashi Nakamura, KatsumiKose
0137. A Lightweight, Portable MRI Brain Scanner Based on a Rotating Halbach Magnet 641Clarissa Zimmerman Cooley, Jason P. Stockmann, Brandon Dean Armstrong, Matthew S. Rosen, Lawrence L. Wald
0138. Target Field Based RF Phase Gradient Transmit Array for 3D TRASE MRI 642Jesse Bellec, Scott B. King, Chen-YiLiu, Christopher P. Bidinosli
0139. An Open Source Mobile NMR Relaxometry Platform 643Michael Twieg, MatthewJ. Riffe, Natalia Gudino, Mark A. Griswold
0140. Magnetic Particle Imaging for Safe Angiography and Stem Cell Tracking 644Emine U. Sarilas. Patrick W. Goodwill, Justin J. Konkle, Laura R. Croft. Kuan Lu, Bo Zheng, Steven M. Conolly
0141. Aging Augments the Suppression Ratio, A MRI Biomarker of Cortical Bone Porosity 645
Yiisu/A. Bhagat, Cheng Li, Shing Chun Benny Lam, Alan C. Seifert, Mahdieh BashoorZadeh, Felix W. Wehrli
0142. Can We Assess Cortical Bone Microstructure with Magnetic Resonance Imaging? 646Won C. Bae, Reni Biswas. Shantanu Patil, Christine Chung, Darryl D. D'Lima, Graeme M. Bydder, Jiang Du
0143. The Porous System Model Suitable to Investigate the Structural Properties of the Cancellous Bone by UsingDiffusion Techniques: Validation in Calcaneus and Femoral Neck 647
Silvia Capuani
0144. Assessment ofBone Marrow Fat Fraction in the Presence of Trabecular Bone: Initial Comparison ofWater-
Fat Imaging with Single-Voxel MRS 648
Dimilrios C. Karampinos, Gerd Melkus, Thomas Baum,Jan S. Bauer, Ernst J. Rummeny, RolandKrug0145. Variation ofLamellar Layer Thickness in Human Menisci on Ultrashort Echo Time (UTE) Imaging:Correlation with Indentation Stiffness 649
Ja-Young Choi, Rem Biswas, Mike Im, Won C. Bae, Sheronda Slatum, Eric Chang, Jiang Du, Graeme M. Bydder, DarrylD.D'Lima, Christine Chung
0146. Correlation Between Quantitative Delayed Contrast-Enhancement in Meniscus and Cartilage in Knee
Osteoarthritis 650
Jasper Van Tiel, Esther Bron, Koen Bos, Stefan Klein, Max Reijman, Jan Verhaar, Gabriel Krestin, Harrie Weinans, GyulaKotek,Edwin Oei
0147. Experimental Influences on the Anisotropies of Multi-ComponentT2 and Tip in Tendon 651
YangXia, Nian Wang0148. The Shear Modulus of the Nucleus Pulposus Measured Using MR Elastography: A Potential Biomarker for
Intervertebral Disc Degeneration 652
Daniel H. Cortes, Jeremy F. Magland, Alexander C. Wright. Dawn M. Elliott
0149. Feasibility of Using MR Elastography in the Intervertebral Disc and Comparison to Finite Element Model 653
Ephraim 1. Ben-Abraham, Jun Chen, Richard L. Ehman
0150. DCEMRI Shows Slower Wash-Out in Lumbar Disc Endplates to Sustain Diffusion of Nutrients Into the
Discs 654
L. Tugan Muftuler, Hon J. Yu, Vance O. Gardner. Dennis J. Maiman
0151. In-vivo 29Si Magnetic Resonance Imaging of Hyperpolarized Silicon Particles 655
Maja Cassidy. Henry Chan. Pratip Bhattacharya, Charles Marcus
0152. Imaging Caz+ Using Fluorine Chemical Exchange Saturation Transfer ("F-CEST) 656
Amnon Bar-Shir, AssafA. Gilad, Kannie W. Y. Chan, Guanshu Liu, Peter C. M. Van Zijl. Michael T. McMahon, JeffW. M. Bulte
0153. A Novel MR-Visible Persistent Apoptosis Marker Validated with Immunohistochemistry 657
Firas Moosvi, Jennifer H. E. Baker, Andrew Yung, Kenneth Curry, Stefan A. Reinsberg0154. Evaluation ofVanadium-Based Contrast Agents for Detection ofEarly Murine Colon Cancer Using MRI, X-
Ray Fluorescence Microscopy and a Novel Method of Image Co-Registrations 658
Devkumar Mustafi. Jesse Ward, Urszula Dougherty, Erica Markiewicz, Marc Bissonnette, Stefan Vogt, Gregory S. Karczmar
0155. Chemical Doping ofIron Oxide Inside Apoferritin to Form an MRI Contrast Agent with High R, and Low
R2 659
Maria Veronica Clavijo Jordan, Kevin M. Bennett
0156. Using Magnetization Transfer Contrast as a Surrogate Marker for the Occurrence of a Foreign BodyReaction in Hydrogel-Based Cell Therapy 660
Kannie W. Y. Chan, GuanshuLiu, Peter C. M. Van Zijl, Jeff W. M. Bulte, Michael T. McMahon
0157. Macrophage Tracking with Heteronuclear Proton MRI 661
Cornelius Faber, Rebecca Schmidt, Nadine Nippe, Klaus Strobel, Max Masthoff, Carsten Holtke, Olga Reifschneider, DanielaDelli Castelli, Silvio Aime, Christoph Bremer
0158. Imaging Oncolytic Virotherapy Delivery Using a CEST Reporter Gene 662
Christian Thomas Farrar, Jason S. Buhrman, Guanshu Liu, AssafA. Gilad, Michael T. McMahon. Giulia Fulci
0159. Bioengineering a Reporter System That Combines a Highly Sensitive CEST and Fluorescence ImagingProbe 663
Amnon Bar-Shir, Yoshinori Kato, ArvindP. Pathak, JeffW. M. Bulte, AssafA. Gilad
0160. A Bright Multi-Imaging Modality Gene Reporter 664
P. Stephen Patrick, Jayne Hammersley, Louiza Loizou, Mikko 1. Kettunen, Tiago B. Rodrigues, De-En Hu, Sui Seng Tee. Robin
Hesketh, Scott K. Lyons. Silvio Aime, Sandra M. Fulton, Kevin M. Brindle
0161. Dependence ofGradient Echo Phase Contrast on the Differential Signal Decay in Subcellular Compartments 665
Wei Li, Hui Han. Arnaud Guidon, Chunlei Liu
0162. Ultra-High-Field 7T in Vivo Normative Atlas of the Hippocampal Subfields Using Susceptibility Weighted
Imaging 666
Maged Goubran, Brendan Santyr, DaveA. Rudko, Joseph S. Gati, Trevor Szekeres, Terry M. Peters. Alt R. Khan
0163. A 7-Tesla Longitudinal Study on Proportion ofVeins in Plaques of Patients with Multiple Sclerosis 667
Assunta Dai-Bianco, Gunther Grabner, Hans Lassmann, MelanieSchemthaner. Claudia Kronnerwetter, Michael Weber, Clemens
Vass, Karl Kircher, Andreas Reitner, Eduard Auff Siegfried Trattnig
0164. An Improved Susceptibility Weighted Imaging Method Using Multi-Echo Acquisition 668
Sung Suk Oh, Se-Hong Oh. Hyunwook Park, Jongho Lee
0165. Flow Compensated Quantitative Susceptibility Mapping for Venous Oxygenation Imaging 669
Bo Xu, Tian Liu, Pascal Spincemaille, Yi Wang
0166. Magnetic Resonance Venography of the Fetal Brain Using Susceptibility Weighted Imaging (SWI) 670
Jaladhar Neelavali. Haacke Mark Ewart. Swati Mody, Lami Yeo, SheenaSaleem. Yashwanlh Katkuri, Pavan Jella. Ray O. Bahado-
Singh, Sonia Hassan. Robert Romero. Moriah Thomason
0167. Susceptibility Weighted Imaging at 3 Tesla Is Superior to Time-Of-Flight-Angiography for the Detection of
Peripheral Thrombi in Patients with Acute Stroke 671
Alexander Radbruch, Johanna Mucke, Matthias Roethke, Heinz-Peter Schlemmer, Sabine Heiland, Martin Bendszus, Stefan Rohde
0168. Regularized QSM in Seconds 672
Berkin Bilgic, Itthi Chatnuntawech, Audrey Peiwen Fan, Elfar Adalsteinsson
0169. Susceptibility Mapping Using Regularization Enabled Harmonic Artifact Removal 673
Hongfu Sun, Alan H. Wilman
0170. Efficient and Automatic Harmonic Field Pre-Filtering for Brain Quantitative Susceptibility Mapping 674
Ludovic De Rochefort, Hongchen Wang, Paulo Loureiro De Sousa, Jean-PaulArmspach
0171. Accelerated Human Cortical Microstructural Changes from 35 to 40 Weeks ofGestation Characterized with
DTI 675
Qiaowen Yu, Tina Jeon, Shuwei Liu, Hao Huang0172. Evaluation of the Longitudinal Relaxation Rate of Blood in Neonates 676
Jill Brill De Vis, Jeroen Hendrikse, Nikki Dieleman. Floris Groenendaal, Karina J. Kersbergen, Linda S. De Vries. Manon J. N. L.
Benders, Esben Thade Petersen
0173. Quantitative Measurement of Deep Medullary Venous in Susceptibility Weighted Imaging.-Comparison of
Hypoxic-Ischemic and Normal Neonates 677
Ning Ning, Xianjun Li, Jie Gao, Yumiao Zhang, Jianghong Han, XueLuo, Gang Niu, Youmin Guo, EdX. Wu, Jian Yang
0174. Increased Incidence of Intracranial Hemorrhage in Extremely Premature Infants Treated with HypercapnicVentilation 678
XiaweiOu, Charles M. Glasier, Raghu H. Ramakrishnaiah, Sarah B, Mulkey, Vivien L. Yap, Jeffrey R. Kaiser
0175. Quantitative Assessment of Cerebral Metabolism Rate of Oxygen in Neonates 679
Peiying Liu, HaoHuang, Nancy K. Rollins, Tina Jeon, Lina Chalak, Hanzhang Lu
0176. Whole-Brain Connectivity Mapping in Infants Reveals Widespread Areas ofWhite Matter DamageAssociated with Prematurity 680
Anand Pandit, EmmaRobinson, Paul Aljabar, Gareth Ball, loannis S. Gousias, Zi Wang, Giovanni Montana, Jo Hajnal, Daniel
Rueckert, Serena J. Counsell, A. DavidEdwards
0177. Atlas-Based Quantification of Diffusion Tensor Imaging (DTI) and Resting-State Functional MRI (Rs-FMR1) in Children with Cerebral Palsy (CP) 681
Shako Yoshida, Andreia V. Faria, Diane L. Damiano, Chunxiao Zhou, Alexander Hoon, Elaine Stashinko, Kenichi Oishi, James J.
Pekar, Susumu Mori
0178. The Structural Connectome of the Human Brain in Agenesis of the Corpus Callosum 682
Julia P. Owen, Yi-Ou Li, EtayZiv, Zoe Slrominger, Jacquelyn Gold, Polina Bukshpun, Mari Wakahiro, Elliott Sherr, Pratik
Mukherjee
0179. Revealing Morphological Connectome Alternation in Autistic Brain 683
Feng Shi. Li Wang, Ziwen Peng, Chong-Yaw Wee, Dinggang Shen
0180. Altered Structural and Functional Connectivity in Late Preterm Preadolescents 684
Jessica L. Wisnowski, Vincent J. Schmithorst, Rafael C. Ceschin, Patricia Corby. Hanna Damasio, AshokPanigrahyRectal Carcinoma: A "Distance Approach" 685
Stephanie Nougaret
Adnexal Mass Characterization 690Isabelle Thomassin-Naggara
Endometrial Carcinoma: Impact ofMR on Management 691Caroline Reinhold
Cervical Carcinoma: Staging & Follow-Up 693Evis Sola
Liver Lesions: Added Value of Diffusion MRI 694
Bachir Taouli
Renal Lesions: Added Value of Diffusion MRI 700Harriet C. Thoeny
Pelvis: Added Value of Diffusion MRI 702Nandita M. Desouza
Response to Treatment 703Kinh Gian Do
Liver Cell Adenoma: A New Perspective 704Anwar R. Padhani
Non-Contrast MR Angiography ofAbdomen 708
Mitsue Miyazaki
MR Venography 709
Pejman Ghanouni
The Basics 710Alexander P. Lin
Using Edited MRS to Reveal Extra Metabolites 711Richard A. Edden
Techniques for Evaluating Right Ventricle & Pulmonary Arteries 713
MichaelSalerno
Clinical Applications of MRI for Evaluating the Right Ventricle 714Susan Matulevicius
Clinical Applications of MRI in Pulmonary Vascular Disease 717Jens Vogel-Claussen
High Angular Resolution Diffusion Imaging 718Maxime Descoteaux
Susceptibility-Weighted Imaging (SWI) 719Chunlei Liu
Basic Image Manipulation & Measurements 720
Stephen J. WasllingPractical Tips & Tricks to Maximize Repeatability 721
Mark A. Horsfield
Mapping MRI Contrast Enhancement with Histology 722
Kai-Hsiang Chuang
Magnetic Resonance Histology- Cool Images- But Who Cares? 727
G. Allan Johnson. Alexandra Badea, Evan Calabrese, Chuntei Liu, Luke Xie
Diffusion Basics 728
Selh A. Smith
Diffusion Analysis - Absolute Beginner's Guide to Neuroimaging Methods 729
David Raffelt
Technical Aspects - How to Do It 730
Kyung Sung
Advanced MSK MRI Techniques with Clinical Applications 731
William B. Morrison
Fast & Super-Fast Imaging 732
Daniel K. Sodickson
MR in the Emergency Room 733
Pamela Schaefer
Parallel Imaging 736
Michael S. Hansen, Philip J. Beatty
0181. How Clinical Research Trials Changed the Use ofBreast MRI 737
Constance D. Lehman
0182. Innovations in Breast MRI N/A
Donald B. Plewes
0183. Evolution ofBreast Imaging: Beyond Mammomgraphy 741
Christiane K. Kuhl
0184. High Temporal Resolution Retrospective Real-Time Cine Imaging: Shortened Acquisition Via Nonlinear
Reconstruction 743
Hui Xue, Peter Kellman, Andrew E. Arai. MichaelSchacht Hansen
0185. Multi-Node, Multi-GPU Radial GRAPPA Reconstruction for Online, Real-Time, Low-Latency MRI 744
Haris Saybasili. Daniel A. Herzka, Kestutis Barkauskas, Nicole Seiberlich. MarkA. Griswold
0186. Multicenter Evaluation of Dynamic Three-Dimensional Whole-Heart Myocardial Perfusion Imaging at 3.0
Tesla for the Detection of Coronary Artery Disease Defined by Fractional Flow Reserve 745
Robert Manka, Rolf Gebker, Lukas Wissmann, RoyJogiya, Manish Motawani, Michael Frick, Sebastian Reinartz. Bernhard
Schnackenburg, Eike Nagel, Sven Plein, Sebastian Kozerke
0187. Deformable Registration for Improved Constrained Reconstruction of Ungated Cardiac Perfusion MRI 746
Ganesh Adluru, Edward V. R. Dibella
0188. Accelerated Sub-Mm Whole-HeartCoronary MRI: Compressed Sensing Vs. Parallel Imaging 747
Mehmet Akcakaya, Tamer A. Basha, Raymond H. Chan, Warren J. Manning, Reza Nezafat
0189. Autofocusing Nonrigid Respiratory Motion Correction for 3D Cones Coronary MR Angiography 748
R. Reeve Ingle. Holden H. Wu, Nii OkaiAddy, Joseph Y. Cheng, Bob S. Hu, Dwight G. Nishimura
0190. Accelerated 4D Flow CMR Imaging with Variable-Density Random Undersampling and Parallel Imaging 749
JingLiu, Petter Dyverfeldt, MichaelHope, DavidA. Saloner
0191. Quantification of Hepatic Blood Flow in Portal Hypertension Using 4D-Flow MRI: A Meal Challenge Study 750
Alejandro Roldan-Alzate, Alex Frydrychowicz, Oliver Wieben, Scott B. Reeder
0192. The 30-Second Time-Of-Flight Exam: Improving Image Quality with Modern Acceleration Methods 751
Jerome Yerly, RichardFrayne, R. MarcLebel
0193. Ultrafast Non-Contrast Enhanced 4D Dynamic MRA with 3D Stack-Of-Stars Golden Angle Radial
Acquisition and KWIC Reconstruction 752
Robert X. Smith, Lirong Yan, Stanislas Rapacchi, Yiqun Xue, Subashini Srinivasan. Daniel B. Ennis, Peng Hu, HeeKwon Song,
Danny J. J. Wang
0194. Effect of Risk-Reducing Salpingo-Oophorectomy on Breast MRI Fibroglandular Tissue and Background
Parenchymal Enhancement in BRCA1/2 Mutation Carriers: A Quantitative Assessment 753
Shandong Wu, Susan M. Domchek, Michael J. Deleo, Emily F. Conanl, Susan P. Weinstein, Despina Kontos
0195. Parenchymal Enhancement in the Contralateral Normal Breast of Patients Undergoing Neoadjuvant
Chemotherapy Measured by DCE-MRI754
Jeon-Hor Chen, HonJ. Yu, Christine Hsu, MuqingLin, Rita S. Mehta. Min-YingSu
0196. Diffusion Weighted Imaging of the Breast at 7T - Ready for Clinical Application? 755
Olgica Zaric, Katja Pinker, Stephan Gruber, David Porter, Thomas Helbich, Siegfried Trattnig, Wolfgang Bogner
0197. Simultaneous Diffusion MRI and PET Imaging ofBreast Cancer Patients 756
Eric E. Sigmund, Sungheon Kim, Christian Geppert, Linda Moy, David Paul, Christopher B. Glielmi, Kimberly Jackson. Kamil
Bani-Baker, Amy Melsaether
0198. Compartmental Diffusion in Breast Cancer 757
Edna Furman-Haran, Myra Feinberg-Shapiro, Erez Eyal, Dov Grobgeld, Noemi Weisenberg. Noam Nissan, Tania Zehavi,
Hadassa Degani
0199. Reproducibility or Chemical Exchange Saturation Transfer (CEST) MRI ofthe Breast at 7 Tesla 758
Adrienne N. Dula. Lori R. Arlinghaus. Jason M. Williams. Richard G. Abramson. Richard D. Dortch. Seth A. Smith. Thomas E.
Yankeetov
0200. Separation of Benign and Malignant Breast Lesions Using Pharmacokinetic Analysis for a Biopsy Cohort 759
Melanie Freed, AnaPaulaKlautau Leite, Jin Zhang, Melanie Moccaldi. Kai Tobias Block. Linda Moy. Sungheon Kim
0201. Impact of Factors Affecting the Accuracy of Breast MRI in Determining Residual Tumor Size FollowingNeoadjuvant Chemotherapy 760
Jeon-Hor Chen. Shadfar Bahri. RilaS. Mehla. Philip M. Carpenter. Christine E. McLaren, Wen-Pin Chen. David J. B. Hsiang,Min-YingSu
0202. Comparison of a High Spatial Resolution DTI Sequence to Standard DTI for Evaluating Fractional
Anisotropy ofBreast Tumors 761
Lisa J, Wilmes. Cheng-Liang Liu, David C. Newitt, Suchandrima Banerjee, Rebekah L. McLaughlin, Evelyn Proctor, Emine U.
Sari/as, Ajit Shankaranarayanan, Nola M. Hylton0203. Manganese-Enhanced MRI for Early Detection of Breast Cancer Metastatic Potential 762
Joris Tchouala Nofiele, Gregory J. Czarnota, Hat-Ling Margaret Cheng0204. The Robustness ofDSC-PWI for Acute Stroke Imaging; Timing Is Everything: The Vanishing Perfusion
Abnormality 763Irene Klaerke Mikkelsen. Lars Riisgaard Ribe, SusanneLise Bekke, Kim Mouridsen, Leif0stergaard
0205. Multi-Delay Multi-Parametric Arterial Spin-Labeled Perfusion MRI in Acute Ischemic Stroke -
Comparison with Dynamic Susceptibility Contrast Enhanced Perfusion Imaging 764
Danny J. J. Wang, David S. Liebeskind, Joe X. Qiao. Matthias Giinther, Whitney B. Pope, Jeffrey L. Saver, Noriko Salomon. JeffryR. Alger
0206. Derivation of Flow Information from a Hypocarbia Challenge Study Using Time Delay Correlation
Processing 765
Blaise Frederick, Yunjie Tong, Megan Strother, Lisa Nickerson, Kim Lindsey, Manus Donahue
0207. Noninvasive Multi-Echo Vessel-Encoded Arterial Spin Labeling Reactivity for More ComprehensiveQuantification of Hemodynamic Compensation: Development and Clinical Implementation in 50 Patients with
Cerebrovascular Disease 766
Manus J. Donahue, Paul Clemmons, Ricardo Andal, Robert Singer, Diane Brown, Morgan Anderson, Dan Claassen, John
Connors, Lisa Hermann, Lori Jordan, Howard Kirshner, J. Mocco, Ryan Moore, Anne O'Duffy, Derek Riebau. Allen Sills. MeganStrother
0208. Cerebral Perfusion and Vascular Reactivity in Insulin Resistance and Obesity 767
Henry Rusinek, JennyHa, Po Lai Yau, Aziz Tirsi, Wai Hon Tsui, Antonio Convit
0209. Evaluation of a Multiparamteric QBOLD Approach in Acute Stroke Patients 768Julien Bouvier, OlivierDetante, Irene Tropres, Sylvie Grand, David Chechin, Jean-Francois Le Bos, Alexandre Krainik,Emmanuel Luc Barbier
0210. Brain Connectivity and CBF Canges Fllowing Motor Training by MI-BCI Combined with TDCS in Stroke
Patients 769
Xin Hong, Yan Zhi Ong, lrvin Teh, FatimaAHNasrallah, ZhongKang Lu, Wei PengTeo, Cuntai Guan, Kai KengAng, Kok Soon
Phua. Ling Zhao, Effie Chew, Kai-Hsiang Chuang
0211. Dual-Echo Diffusion-Weighted EPI for Better Sensitivity to Acute Stroke 770
Samantha J. Holdsworth. Stefan Skare, Kristen Yeom, Michael U. Antonucci, Jalal B. Andre, Jarrett Rosenberg, Matus Straka,
Nancy J. Fischbein, Greg Zaharchuk, Roland Bammer
0212. Subcortical Volumetric Differences in Children with Sickle Cell Disease and Silent Infarction 771
Jamie M. Kawadler, Jonathan D. Clayden, Fenella J. Kirkham, ChristopherA. Clark
0213. Amide Proton Transfer (APT) Imaging ofAcute Cerebral Infarction: A Preliminary Study on Clinical
Patients 772
Takashi Yoshiura, Akio Hiwatashi, Osamu Togao, Jochen Keupp, Koji Yamashita, Kazufumi Kikuchi, Yuriko Suzuki, Makoto
Obara, Hiroshi Honda
0214. In vivo Spectroscopic Imaging of2-Hydroxyglutarate in Human Gliomas at 7.0 T 773
Sandeep Ganji, Keith M. Hulsey, Elizabeth A. Maher, Changho Choi
0215. Imaging Real-Time Cancer Metabolism with MAD-STEAM HP "C MRSI 774
Christine Leon, Adam B. Kerr. Robert A. Bok, Mark Van Criekinge, Galen D. Reed, Klaus Kruttwig, Andrei Goga, John
Kurhanewicz, John M. Pauly, Daniel B. Vigneron, Peder E. Z. Larson
0216. Partial Volume Corrected CMROj Determination in a Glioblastoma Patient by 170 MRI 775
Stefan H. Hoffmann, AlexanderRadbruch, WolfhardSemmler, Armin M. Nagel
0217. Improved Quantification ofCholine in Breast MRS Using Dixon Imaging Water Referencing 776Lenka Minarikova, Stephan Gruber, Wolfgang Bogner, Katja Pinker-Domenig, Siegfried Trattnig, Thomas Helbich. Marek
Chmelik
0218. Using Paired Tissue and Serum Samples to Characterize Human Lung Cancer Metabolomics with ex vivo
1HHRMAS MRS 777
Hailiang Huang, Emily Decelle, Yannick Berker, Andreas Schuler. Isabel Dittman, Li Su, Eugene J. Mark, Mark J. Daly. David C.
Christiani, Leo L. Cheng0219. In Vivo Evidence for Abnormal Cerebral Bioenergetics in Schizophrenia Measured by 31P MagnetizationTransfer Spectroscopy 778
Fei Du, Alissa Cooper, Thida Thida, Selma Sehovic. Scott Lukas, Bruce Cohen, Xiaoliang Zhang, Dost Ongur0220. Longitudinal Magnetic Resonance Spectroscopy in Premanifest and Early Huntington Disease 779
Bretta Russell-Schulz, Alex L. Mackay, Blair R. Leavitt
0221. Serial Proton MR Spectroscopy ofGray and White Matter in Relapsing-Remitting Multiple Sclerosis 780Ivan I. Kirov, AssafTal, James S. Babb. Joseph Herbert. OdedGonen
0222. Cerebral Glucose Metabolism During Euglycemia and Hypoglycemia in Patients with Type 1 Diabetes 781
Kim C. C. Van De Ven, Marinette Van Der Graaf, Bastiaan E. De Galan. Cees J. Tack, ArendHeerschap
0223. Metabonomics ofGastrointestinal Mucosa in Celiac Disease Using In-Vitro Proton NMR Spectroscopy 782
Naranamangalam R. Jagannathan, Uma R. Sharma, Sujeet R. Mewar, Govind K. Makharia
0224. MR-Guided Focused Ultrasound for the Treatment of Essential Tremor: Initial Experience on MR-Based
Targeting and Temperature Monitoring 783
Yuexi Huang, Nir Lipsman, Michael L. Schwartz. Andres M. Lozano, Kullervo Hynynen
0225. Pain Palliation in Patients with Bone Metastasis Using MR-Guided Focused Ultrasound with Conformal
Bone System: A Preliminary Report 784
Bio Joo, Mi-Suk Park, Soo Hyun Lee, Hye Jin Choi, Young Tag Oh, hay Rachmilevitch, Ori Alar
0226. MRI-Guided Focused Ultrasound-Mediated Drug Delivery to Pancreatic Cancer: Safety and Efficacy 78S
Nalalya Rapoporl, Allison H. Payne, Christopher Dillon, Jill E. Shea
0227. Apparent Diffusion Coefficient Decrease During Thermal Ablation ofthe Prostate as an Early Indicator for
Loss ofTissue Viability 786
Juan C. Plata, Andrew B. Holbrook. Michael Marx, VasantSalgaonkar, Peter Jones, Chris J, Diederich, Aurea Pascal-Tenorio.
Donna Bouley. Graham Sommer, Kim R. Butts Pauly
0228. Selective Brain Cooling in Sheep by Intra-Ventricular Catheters: A 7T BIRDS Study 787
Daniel Coman, Yuegao Huang, John W. Simmons, James A. Goodrich, Brain McHugh, John A. Elefteriades, Douglas L. Rothman,Fahmeed Hyder
0229. Comprehensive Comparison ofSix Referenceless PRF Shift MR Thermometry Methods 788
Changjun Tie, Chao Zou, MengyueHe, Wensha Guo, Yiu-Cho Chung, Xin Liu
0230. In Vivo Validation ofT2-Based MR Thermometry in Adipose Tissue Layers for HIFU Near-Field
Monitoring 789
Paul Baron, Mario Ries. Martijn De Greef, Roel Deckers, MaxKohler, Jukka Tanttu, Chrit T. W. Moonen. Lambertus W. Bartels
0231. Non-Invasive In Vivo Loss Tangent Imaging: Thermal Sensitivity Estimation at the Larmor Frequency 790
Narae Choi, Joonsung Lee, Min-Oh Kim, JaewookShin, Dong-Hyun Kim
0232. Towards Improving Predictive Capabilities of MR-ARFI for Transcranial Focused Ultrasound Therapy 791
Elena Kaye, Yoni Herzberg, Gil Navon, Kim R. Butts Pauly
0233. Hybrid US-MR Guided HIFU Treatment Method with 3D Motion Compensation 792
Zarko Celicanin, Vincent Auboiraux, Oliver Bieri, Lorena Petrusca, Yutaka Natsuaki, Francesco Santini, Magalie Viallon, Klaus
Scheffler, Rares Salomir
0234. Casein Coated Magnetic Iron Oxide Nanoparticles forTargeted Imaging and Drug Delivery 793
Jing Huang, Hyunseok Kang, Liya Wang, Run Lin, Xianghong Peng, Lily Yang, DongMoon Shin, Hui Mao
0235. Sustained Restoration ofLV Dysfunction in a Pig Ischemia-Reperfusion Injury Model Using Human
Amnion-Derived Mesenchymal Stem Cells Tracked by Manganese-Enhanced MR1 794
Rajesh Dash, Paul Kim, Yuka Matsuura, Fumiaki Ikeno, Jennifer Lyons, Xiaohu Ge, Scott Metzler, Ngan Huang, Patricia Nguyen,Joseph Wu, John Cooke, Pilar Ruiz-Lozano, Robert C. Robbins. Michael V. McConnell, Alan C. Yeung, Phillip Harnish, Phillip C.
Yang
0236. MR Imaging ofCancer Vasculature Using VEGF Receptor-Targeted Dual Contrast Labeled Liposomes 795
Yoshinori Kato, Wenlian Zhu, Marina V. Backer, Ronnie C. Mease, SusantaK. Sarkar, Joseph M. Backer, Dmitri Artemov
0237. E-Selectin Targeted USPIO Enhancement of Atherosclerotic Plaques Visualizes Treatment Response and
Mechanism ofAction 796
Brigit Den Adel, Ernst Suidgeest, Carmen Burtea, Marieke Stammes, Kim Van Der Heiden, Sophie Laurent, Robert E. Poelmann,
RobertN. Muller, Louise Van Der Weerd
0238. Two Component System for MR/optical Image-Guided Delivery and Cell Surface Targeting of HER2(+)Cancer Cells 797
Sudalh Hapuarachchige, Wenlian Zhu, Yoshinori Kato, Dmitri Artemov
0239. A PSMA-Targeted Theranostic Nanoplex Combining TRAIL Gene CDNA and Prodrug Enzyme Deliveryfor Prostate Cancer Treatment 798
Zhihang Chen, Marie-France Penet, Balaji Krishnamachary, Sangeeta Ray, Cong Li, Paul T. Winnard, Martin G. Pomper, Zaver
M. Bhujwalla
0240. EGFR MAb-Bioconjugated Superparamagnetic Iron Oxide Nanoparticles as a Specific MRI Contrast Agentfor Detection of Brain Glioma In Vivo 799
Tao Mu, Yuanyuan Qin, Yan Zhang, He Wang, Wenzhen Zhu
0241. Integrated PET/MRI with MGa-DOTATOC in Patients with Neuroendocrine Tumors - First Results 800
Karsten Beiderwellen, Thorsten D. Poeppel, Verena Hartung-Knemeyer, Christian Buchbender, HilmarKuehl, Andreas Bockisch,
Thomas C. Lauenstein
0242. Molecular Imaging of Cancer with Paramagnetic Vesicles Targeted to Phosphatidylserine 801
Patrick Winter, John Pearce, Zhengtao Chu, Jing-Huei Lee, Xiaoyang Qi
0243. In Vivo Quantification of Inflammation Burden in an Experimental Allergic Encephalomyelitis Rat Model
Using Fluorine-19 MRI 802
Jia Zhong, Penelope Morel, Hongyan Xu, Lisa Pusateri, Eric T. Ahrens
0244. Tl-Weighted Imaging of Lumbar Spine Using Multiband Slice Accelerated Spin Echo 803
Dingxin Wang, Peter D. Kollasch, EdwardJ. Auerbach, Steen Moeller, Bhat Himanshu, Kamil Ugurbil, Vibhas Deshpande
0245. Fast T2 Weighted Imaging with PSIF in the Abdomen at 3T 804
Chao Zou, Wensha Guo. Xin Liu, Yiu-Cho Chung
0246. A Variable Bandwidth Radial Gradient and Spin-Echo (VB-RadGRASE) Method for Improved T2 and Fat-
Water Parameter Estimation 805
Mahesh Bharath Keerthivasan, Jean-Philippe Galons, Puneet Sharma, Diego R. Martin, Ali Bilgin. Maria 1. Altbach
0247. Multi-Echo Acquisition of 3D TOF and SWI of Radiation-Induced Cerebral Microbleeds at 7T 806
Wei Bian, Suchandrima Banerjee, Douglas A. C. Kelly, Susan M. Chang, Sarah J. Nelson. Janine M. Lupo
0248. Optimization ofCube-FLAIR 3D FSE Imaging at 7T 807
Manojkumar Saranathan, Thomas Tourdias, Michael Zeineh, Adam Kerr, Jeffrey D. Bernstein, Geoff A. Kerchner, Brian K. Run
0249. SAR and Scan-Time Optimized 3D Whole-Brain Double Inversion Recovery (DIR) Imaging 808
Eberhard Daniel Pracht, Thorsten Feiweier, Philipp Ehses, Daniel Brenner, Bemd Weber, TonyStocker
0250. Rapid Tracking of Soft Palate Motion During Speech Using Pencil Beam and Turbo Navigators 809
AndrewDavid Scott. Redha Boubertakh, Malcolm Birch, Marie Pinkstone, Marc Eric Miguel
0251. Real-Time MRI Can Differentiate Sleep-Related Breathing Disorders in Children 810
Yoon-Chul Kim. Shirleen Loloyan. Ziyue Wu, Winston Tran, Roberta Kato, Sally L. D. Ward, Michael C. K. Khoo, Krishna S.
Nayak
0252. Fat Saturation for 2D Small-Tip Fast Recovery Imaging UsingTailored 3D Spectral-Spatial Pulses 811
Feng Zhao, Jon-Fredrik Nielsen, Douglas C. Noll
0253. Reduction of Acoustic Noise to Improve Patient ComfortThrough Optimized Sequence Design 812
Eric Yann Pierre, DavidManuel Grodzki, Bjoem Heismann, Vikas Gulani, JeffreySunshine, KechengLiu, Mark A. Griswold
Inflammatory Bowel Disease: Technique 813Sharon E. Clarke
Inflammatory Bowel Disease: Case Studies 815
Stuart A. Taylor
MRI ofPerianal Fistulas 816
Roy S, Dwarkasing
Retrospective Motion Correction for Cardiovascular and Body Imaging 818
Freddy Odille
Clinical & Research Applications ofBone Imaging 825
Thomas M. Link
Free Induction Decay Imaging of Short-Lived Signals 826
Michael Garwood
MRI Assessment ofTrabecular & Cortical Bone Structure & Strength 827
Felix W. Wehrli
Magnetic Resonance Imaging Bone Marrow 830
Xiaojuan Li
Imaging Bone Water Compartments 832
Jiang Du
Clinical Applications of Diffusion Imaging in the Spine 843
Lawrence Neil Tanenbaum
0254. Acute Hemorrhagic Myocardial Infarction Leads to Localized Chronic Iron Deposition: A CMR Study 864
Avinash Kali, Ivan Cokic, Andreas Kumar, RichardL Q Tang, Sotirios A. Tsaftaris, Matthias G. Friedrich, Rohan Dharmakumar
0255. Quantitative T2 Mapping Visualizes Hemorrhage and Edema After Acute Myocardial Infarction in Swine 865
Haiyan Ding, Michael Schar, Elliot R. McVeigh, Henry Halperin, M. Muz Zviman, Roy Beinart, DanielA. Herzka
0256. Tl Mapping After Acute Myocardial Infarction: Multiphase Phase-Sensitive Inversion-Recovery (MpPSIR)Method as Valuable Alternative to the Modified Look-Locker Inversion Recovery (MOLLI) Method 866
Oliver M. Weber, Javier Sanchez-Gonzalez, LeticiaFernandez-Friera, Gonzalo Pizarro-Sanchez, Jesus G. Mirelis, RodrigoFernandez-Jimenez, Luis Jesus Jimenez-Borreguero, Christian Stehning, Valentin Fuster, Borja Ibanez
0257. Combined Saturation/Inversion Recovery Sequences for Improved Evaluation of Scar and Diffuse Fibrosis
in Patients with Arrhythmia or Heart Rate Variability 867
Sebastian Weingartner, Mehmet Akqakaya, Kraig V. Kissinger, Beth Goddu. Sophie J. Berg, Warren J. Manning, Reza Nezafat
0258. Three-Dimensional MOLLI for Myocardial Tl Mapping Using Respiratory Navigation and Inversion Time
Gating 868
Tobias Voigt, Tobias Schaeffter, Rene M. Botnar, JoukeSmink, Markus Henningsson0259. Assessment of Myocardial Radiofrequency Ablation Lesions with 3D High Resolution Free-Breathing T2
Mapping 869Daniel A. Herzka, Haiyan Ding. Farhad Pashakhanloo, Karl H. Schuleri, Aravindan Kolandaivelu, Elliot R. McVeigh, Henry
Halperin, M. Muz Zviman, Roy Beinart
0260. The Dual-IR Sequence Improves the Inter-Observer Correlation in Post-Ablation Atrial Scar Size
Measurements Compared to the Traditional IR Sequence 870
Sarah Anne Peel, Aruna Arujuna, James Harrison, Zhong Chen, Kawal Rhode, Jaswmder Gill, Reza Razavi. Tobias Schaeffter,Rene M. Botnar
0261. Is Fat-Suppression Necessary to Evaluate Remodeling in the Left Atrium with Late Gadolinium
Enhancement? 871
Dana C. Peters, Jaime L. Shaw, James William Goldfarb, Warren J. Manning
0262. A New Method for Accurate Myocardial Tl Mapping Using Variable Angle Long Echo Train Relaxometric
Imaging (VALERI) 872Thanh D. Nguyen, Mitchell A. Cooper, Pascal Spincemaille. Jonathan W. Weinsaft, Martin R. Prince, Yi Wang
0263. Myocardial ATP Turnover Rates in the in vivo Hearts with Post-Infarction Remodeling 873
QiangXiong, Pengyuan Zhang. Lei Ye, Jinfeng Tian, Cory Swingen, Albert Jang, J. Thomas Vanghan, Jianyi Zhang0264. A Multi-Resolution Anatomical Atlas ofthe Human Brainstem Based on Diffusion Tensor Imaging at 11.7T 874
Manisha Aggarwal, Jiangyang Zhang, Olga Pletnikova, Barbara Crain, Juan Troncoso, Susumu Mori
0265. Comparison with Histology of Quantitative MR Properties of the Brain Stem Tissue in 3T and 7T 875Anna I. Blazejewska, SamuelJ. Wharton. Stefan T. Schwarz, James Lowe, Dorothee P. Auer, Richard W. Bowtell, Penelope A.Gowland
0266. Exploring Cortical Cytoarchitecture in High Resolution Rl Maps 876
Jose P. Marques. Rolf Gruetter
0267. High-Resolution Quantitative Tl Maps of the Human Stria of Gennari at 7 Tesla 877Christine Lucas Tardif, Miriam Waehnert. Juliane Dinse, AndreasSchafer, Pierre-Louis Bazin, Robert Turner
0268. Motion-Corrected 350 um Isotropic MPRAGE at 3 T Using Volumetric Navigators (VNavs) 878Matthew Dylan Tisdall, Jonathan R. Polimeni, Andre J. W. Van Der Kouwe
0269. A Simple Method to Denoise MP2RAGE 879Kieran O'Brien. Gimnar Krueger. Francois Lazeyras, RolfGruelter, Alexis Roche
0270. How Much Resolution Is Needed for in-vivo Analysis of Cortical Myeloarchitecture? 880Miriam Waehnerl, Juliane Dime, Christine Lucas Tardif. Andreas Schafer. Stefan Geyer. Pierre-Louis Bazin. Robert Turner
0271. The Fixation Protocol Alters Brain Morphology in ex-vivo MRI Mouse Phenotyping 881
A. Elizabeth De Guzman, Michael D. Wong, Jacqueline A. Gleave, Brian J. Nieman
0272. MRI of Cell Layers in Mouse Brain in Vivo Using Intra- And Extra-Cellular Contrast Agents 882
Takashi Watanabe, Jens Frahm, Thomas Michaelis
0273. Magic Angle Enhanced MR Microscopy of Fibrous Structures in the Eye 883
Kevin C. Chan, Zion Tse, Ning-Jiun Jan, Joel S. Schuman, Seong-Gi Kim. tan A. Sigal
VOLUME 2