Applied Oral Pathology through Interactive
Learning
Applied Oral Pathology through Interactive
LearningInfectious Diseases
Rachel S. Ennis MDH707 Spring 2011
Infectious Diseases
Rachel S. Ennis MDH707 Spring 2011
Infectious DiseasesChapter 4 Objectives
Infectious DiseasesChapter 4 Objectives
Inflammatory and immune response Causes of opportunistic infection Organisms involved in specific
infectious diseases Oral candidiasis; five forms Herpes labialis; clinical features Recurrent intraoral herpes simplex
infection; clinical features Minor aphthous ulcers; clinical features
Inflammatory and immune response Causes of opportunistic infection Organisms involved in specific
infectious diseases Oral candidiasis; five forms Herpes labialis; clinical features Recurrent intraoral herpes simplex
infection; clinical features Minor aphthous ulcers; clinical features
Objectives continued:Objectives continued:
Herpes Zoster; clinical characteristics
Epstein-Barr Virus; four associated diseases
Coxsackie virus and oral manifestations
Oral manifestations of HIV infection; clinical appearance
Herpes Zoster; clinical characteristics
Epstein-Barr Virus; four associated diseases
Coxsackie virus and oral manifestations
Oral manifestations of HIV infection; clinical appearance
Any ideas?Any ideas?
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Acute Necrotizing Ulcerative GingivitisAcute Necrotizing
Ulcerative Gingivitis Edematous and erythematous gingiva Cratered or “punched out”
interdental papillae Painful Foul odor Metallic Taste Associated with decreased resistance Caused by Fusiform bacilli,
and spirochetes
Edematous and erythematous gingiva Cratered or “punched out”
interdental papillae Painful Foul odor Metallic Taste Associated with decreased resistance Caused by Fusiform bacilli,
and spirochetes
Inflammatory and Immune Response
Inflammatory and Immune Response
Inflammatory response: body’s first line of defense against tissue injury and disease-producing microorganisms
Immune response: defends body against injury, remembers past instances of injury
Inflammatory response: body’s first line of defense against tissue injury and disease-producing microorganisms
Immune response: defends body against injury, remembers past instances of injury
Opportunistic InfectionOpportunistic Infection
Alteration in the oral micro flora Organisms that are normally
nonpathogenic are able to cause disease
Alteration in the oral micro flora Organisms that are normally
nonpathogenic are able to cause disease
Opportunistic infections of the oral cavity
Opportunistic infections of the oral cavity
Dental caries
Periodontal disease
Dental caries
Periodontal disease
Infectious Diseases and the organisms involved
Infectious Diseases and the organisms involved
Impetigo: Staph Aureus, Staph pyogenes. Tonsillitis and Pharyngitis: Streptococci, Adenoviruses,
Influenza, and Epstein-Barr virus Tuberculosis: Mycobacterium tuberculosis Actinomycosis: Actinomyces israelii Syphilis: Treponima pallidum Veruca vulgaris: Human papilloma virus Condyloma acuminatum: Human papilloma virus Primary herpetic gingivostomatitis: Herpes simplex
virus Acute Necrotizing Ulcerative Gingivitis: Borrelia
vincentii fusiform bacillus, and spirochete
Impetigo: Staph Aureus, Staph pyogenes. Tonsillitis and Pharyngitis: Streptococci, Adenoviruses,
Influenza, and Epstein-Barr virus Tuberculosis: Mycobacterium tuberculosis Actinomycosis: Actinomyces israelii Syphilis: Treponima pallidum Veruca vulgaris: Human papilloma virus Condyloma acuminatum: Human papilloma virus Primary herpetic gingivostomatitis: Herpes simplex
virus Acute Necrotizing Ulcerative Gingivitis: Borrelia
vincentii fusiform bacillus, and spirochete
ImpetigoImpetigo
Adult male with impetigo Child with impetigo on chin on chin
Adult male with impetigo Child with impetigo on chin on chin
Syphilis chancreSyphilis chancre
Dorsal surface of tongueDorsal surface of tongue
ActinomycosisActinomycosis
Left mandibleLeft mandible
Condyloma acuminatumCondyloma acuminatum
Lower lipLower lip
Oral Candidiasis(thrush)
Oral Candidiasis(thrush)
Pseudomembranous Erythematous Denture stomatitis (chronic
atrophic candidiasis) Chronic hyperplastic candidiasis Angular cheilitis
Pseudomembranous Erythematous Denture stomatitis (chronic
atrophic candidiasis) Chronic hyperplastic candidiasis Angular cheilitis
Angular cheilitisAngular cheilitis
Commissure of lipsCommissure of lips
Pseudomembranous candidiasis
Pseudomembranous candidiasis
Hard palateHard palate
Herpes LabialisHerpes Labialis
Caused by herpes simplex virus
Also called “cold sore or fever blister”
Vermillion of lips
Caused by herpes simplex virus
Also called “cold sore or fever blister”
Vermillion of lips
Herpes LabialisHerpes Labialis
Vesicles on lips and vermillion boarderVesicles on lips and vermillion boarder
Herpes LabialisHerpes Labialis
Lower lipLower lip
Recurrent intraoral herpes simplex infection
Recurrent intraoral herpes simplex infection
Herpes simplex virus Keratinized mucosa (hard palate,
and gingiva May be caused by sunlight, menstruation,fatigue,fever,stress Painful, focal crops of vesicles Prodromal symptoms:
pain,burning,tingling
Herpes simplex virus Keratinized mucosa (hard palate,
and gingiva May be caused by sunlight, menstruation,fatigue,fever,stress Painful, focal crops of vesicles Prodromal symptoms:
pain,burning,tingling
Primary Herpes Simplex Infection
Primary Herpes Simplex Infection
Dorsal surface of tongueDorsal surface of tongue
Minor aphthous ulcersMinor aphthous ulcers
Nonkeratinized mucosa One to several ulcers present No vesicle preceding ulcer Pain <1cm Round to oval Can recur
Nonkeratinized mucosa One to several ulcers present No vesicle preceding ulcer Pain <1cm Round to oval Can recur
Minor aphthous ulcerMinor aphthous ulcer
Floor of mouthFloor of mouth
Major Aphthous UlcerMajor Aphthous Ulcer
Soft palateSoft palate
Herpes ZosterHerpes Zoster
Shingles Unilateral, painful eruption of
vesicles along sensory nerve May affect three branches of
trigeminal nerve Prodromal symptoms: pain,
burning,paresthesia May last several weeks
Shingles Unilateral, painful eruption of
vesicles along sensory nerve May affect three branches of
trigeminal nerve Prodromal symptoms: pain,
burning,paresthesia May last several weeks
Herpes ZosterHerpes Zoster
ShinglesShingles
Varicella ZosterVaricella Zoster
Lips and palate Lips and palate
Epstein-Barr VirusEpstein-Barr Virus
Infectious Mononucleosis Palatal petichiae kissing disease Nasopharyngeal carcinoma Burkitt lympoma Hairy Leukoplakia usually on lateral border of tongue
Infectious Mononucleosis Palatal petichiae kissing disease Nasopharyngeal carcinoma Burkitt lympoma Hairy Leukoplakia usually on lateral border of tongue
Hairy LeukoplakiaHairy Leukoplakia
Lateral boarder of tongueLateral boarder of tongue
CoxsackievirusCoxsackievirus
Discovered in Coxsackie, NY Transmission by fecal-oral
contamination, saliva, respiratory droplets
May cause: Herpangina Hand-Foot-and Mouth Disease Acute Lymphonodular Pharyngitis
Discovered in Coxsackie, NY Transmission by fecal-oral
contamination, saliva, respiratory droplets
May cause: Herpangina Hand-Foot-and Mouth Disease Acute Lymphonodular Pharyngitis
Coxsackie virusCoxsackie virus
Sores on dorsal surface of tongue and palateSores on dorsal surface of tongue and palate
HIV and Oral LesionsHIV and Oral Lesions Candidiasis Herpes simplex infection Herpes Zoster Hairy Leukoplakia Human papilloma virus lesions Atypical gingivitis and periodontitis Kaposi sarcoma Non-Hodgkin lymphoma Aphthous ulcers Mucosal pigmentation Bacterial salivary gland enlargement and xerostomia Spontaneous gingival bleeding resulting from
thrombocytopenia
Candidiasis Herpes simplex infection Herpes Zoster Hairy Leukoplakia Human papilloma virus lesions Atypical gingivitis and periodontitis Kaposi sarcoma Non-Hodgkin lymphoma Aphthous ulcers Mucosal pigmentation Bacterial salivary gland enlargement and xerostomia Spontaneous gingival bleeding resulting from
thrombocytopenia
HIV associated thrushHIV associated thrush
Soft palateSoft palate
PapillomaPapilloma
Papilloma on soft palatePapilloma on soft palate
Papilloma Papilloma
Lateral boarder of tongueLateral boarder of tongue
PapillomaPapilloma
Buccal MucosaBuccal Mucosa
Kaposi sarcomaKaposi sarcoma
HIV infectionHIV infection
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ReferencesReferences
Ibsen, O., Phelan, J.A. (2009). Oral pathology for the dental hygienist, 5thed.
St. Louis, MO: Saunders Elsevier.
Langlais, R. P. , Miller, C.S. , Nield-Gehrig, J. S. (2009) Color atlas of common
oral diseases, 4thed. Philadelphia, PA: Lippincott Williams and Wilkins.
Ibsen, O., Phelan, J.A. (2009). Oral pathology for the dental hygienist, 5thed.
St. Louis, MO: Saunders Elsevier.
Langlais, R. P. , Miller, C.S. , Nield-Gehrig, J. S. (2009) Color atlas of common
oral diseases, 4thed. Philadelphia, PA: Lippincott Williams and Wilkins.