Brain Tumors

Almario G. Jabson, M.D.

Incidence: Metatasis– most common Primary Brain Tumors–

Glioma

Site: adults: supratentorial children: infratentorial

Classification

WHO: Neuroepithelial:

Astrocyte- astrocytomas Oligodendrocytes- olidendrogliomas Ependymal cells and choroid plexus- ependymoma and choroid plexus papilloma Neurons: ganglioglioma, gangliocytoma, neuroblastoma Pineal Cells: Pineocytoma, pineoblastoma Embryonic: PNET

Meninges: meningioma Nerve Sheath Cells: Neuroma Neurofibroma Blood Vessels: Hemangioblastoma Germ Cells: Germinoma, Teratoma Tumors of maldevelopmental Origin-

Craniopharyngioma, Epidermoid/Dermoid Cysts, Colloid Cyst

Anterior Pituitary Gland: Pituitary Adenoma

Presentation

Mass Effect– Increased ICP Focal Damage- Loss or disturbed function including siezures

Disturbed Function

Diagnostics

Skull X ray: little value CT Scan with Contrast MRI with Gadolinium Angiography

Management

Anticonvulsants: Mannitol Furosemide Operative Management Radiotheraphy SRS Chemotheraphy

Intrinsic Brain Tumors

Astrocytoma Grade I Pilocytic Grade II Low grade Astrocytoma fibrillary and protoplasmic Grade III Anaplastic Astrocytoma Grade IV Glioblastoma Multiforme

Oligodendroglioma: Metastatic Tumors:

Extrinsic Brain Tumors Meningioma

Pituitary Adenoma Hormone effects Visual disturbance

Craniopharyngioma

Ependymoma

Choroid Plexus Papilloma

Intrinsic Post Fossa Tumors Medulloblastoma

Cerebellar Astrocytoma Hemangioblastoma

Extrinsic infratentorial Tumors Vestibular Schwnomma

Meningioma