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BENEFICIAL TREATMENTS OF
CATS WHISKERS(ORTHOSIPHON STAMINEUS)
SHUKRI BIN JAFFAR
MEB 040045
ENGLISH FOR BIOMEDICALSCIENCE
MS. JOTHIMALAR
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OUTLINEIntroductionObjectivesMethodologyDiscussionConclusion
RecommendationsReferences
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Originates fromSouth East Asia and
subtropical AustraliaFlowers were comeby two colors whichwas the purple and
white colorTraditional remedyto many type
diseases :oKidney problemso Livero Gallbladdero
Urinary tract
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Bioactive compoundwas the maincomponents for
research purpose.o5-hydroxy-6, 7, 3,4-tetramethoxyflavon
eo 4, 5, 6, 7-tetramethoxyflavone
Studies of Mariam A.
et al of extract catswhiskers leaf wasuseful where theirstudy on diabetic have
shown significant in
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Amzad M. study was
examined thechemical compositionand anti-fungalproperties of oils and
crude extracts of catswhiskers.Significant findingsof anti-fungal
properties :oBotrytis cinereao Rhizoctoniasolani
o Fusarium solani
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Khamsiah and
Akawuah study hasproved to befunctional asantioxidant at
formed of phenolicgroup To prevent the
diseases:oCoronary heartdiseaseso Cancerso Other aging
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The aims of the study areoTo determine the rolesof bio-active compound in
Orthosiphon stamineusoTo determine the typesof method used fordetecting the componentsin Orthosiphon stamineus
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Effects ofOrthosiphon stamineus aqueous extract onplasma glucose concentration and lipid profile in normal
and streptozotocin-induced diabetic rats
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NORMALRATS
INDUCEDDIABETIC
RATS
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After 14 days, therats blood samples
were collected todetermine :
Blood sugar Blood urea
nitrogen (BUN)Alanineaminotransferse(ALT) Asparateaminotransferase(AST)
Cholesterol Tri l cerides
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Chemical composition and anti-fungal properties of theessential oils and crude extracts ofOrthosiphon
stamineus Benth
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Anti-fungal activity &Minimum inhibitoryconcentration (MIC)
R.solani
B. cinereaF. solani
Colletotricucapsici
P. capsici
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Sinensetin, eupatorin, 3-hydroxy-5, 6, 7,4-tetramethoxyflavone and rosmarinic acid
contents and antioxidative effect ofOrthosiphon
stamineus from Malaysia
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Study on Orthosiphonstamineus aqueous
extraction were showedsignificant reducing theplasma glucoseconcentration on both
normal and diabetic rats.After 14 days, thetested rats were shown
significant in decreasingthe triglyceride and in asimilar way to increasethe plasma HDL-
cholesterol
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Proves that the
leaves ofOrthosiphonstamineus have
properties of anti-fungal andbacteriostatic .Composition inOrthosiphonstamineus essentialoils had shownsi nificant stud
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Methanol
extracts ofOrthosiphonstamineus were
showed activityof antioxidant. Antioxidant
activity wascorrelation withthe total
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Orthosiphon stamineus had showed
that, therehave many potential rolesespecially in treatment Reduced the plasma glucoseconcentration and triglycerideAct as natural fungicides to against thephytopathogensNine components inside essential oils of
Orthosiphon stamineus are the maincompound to be anti-fungal properties.Orthosiphon stamineus to be haveantioxidant properties
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Arebi, T, Z. Ismail and N. Ismail, Effect of flavonoids from Orthosiphonstamineus and Malpighis coccigera on the in vitro growth of calcium oxalatecrystals in human urine. In: proceedings of the International Conference onthe Use of the Traditional Medicine and Other Nature Products in healthCare. Chan, K.L., A. Hussin, A. Adikun, K..H. yuen, M.Z. Asmani and Z. Ismail,(Eds.). Universiti Sains Malaysia Press, Penang, Malaysia, 1993, 435-438.
Burkill, I.H., A dictionary of the economic products of the Malay Peninsula.Volume II. Art Printing Works Publishers, Kuala Lumpur, 1966.
G.A. Akowuah , I. Zhari, I. Norhayati, A. Sadikun, S.M. Khamsah.Sinensetin, eupatorin, 30-hydroxy-5, 6, 7, 40-tetramethoxyflavone androsmarinic acid contents and antioxidative effect ofOrthosiphon stamineusfrom Malaysia. Food Chemistry 87 (2004) 559566.
Hsu, F.L., Chen, Y.C., Cheng, J.T,. Caffeic acid as active principle from thefruit ofXanthium strumarium to lower plasma glucose in diabetic rats. PlantaMedica 2000, 66, 228230.agarath I.B and L.T. Ng. Herbs-The green pharmacy of Malaysia. Vinpress
Sdn. Bhd and Mardi, Kuala Lumpur 2000.
Lee, W.L., Micropropation and cell culture of misai kucing (Orthosiphonstamanues Benth) and detection of rosmarinic acid in the in vitro cultures.
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M. Amzad Hossain, Zhari Ismail, Atiqur Rahmam,and Sun ChulKang. Chemical composition and anti-fungal properties of the essentialoils and crude extracts of Orthosiphon stamineus Benth, Industrial Cropsand Products, 2008, 27 (3) : 328-334.
Olah, N.K., Radu, L., Mogosan, C., Hanganu, D., Gocan, S..Phytochemical and pharmacological studies on OrthosiphonstamineusBenth. (Lamiaceae) hydroalcoholic extract. J. Pharma. Biomed. Anal.2003. 33, 117123.
Sriplang. K, et alEffects ofOrthosiphon stamineus aqueous extract onplasma glucose concentration and lipid profile in normal andstreptozotocin-induced diabetic rats. Journal of Ethnopharmacology 2007,109: 510.
Rice-Evans, C. A., Miller, N. J., Paganga, G. Structure-antioxidant
activity relationships offlavonoids and phenolic acids. Free Radical Biol and Med, 1996, 20(7):933-956.
S.m.Khamsah, G. Akowah, I. Zhari. Antioxidant activity and phenoliccontent oforthosiphonstamineus benth from different geographical
origin. Journal of sustainability science and management 2006, 1(2):14-20
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THANK YOU
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QUESTION ?