CS # 52 - Tuberculous meningitisCS # 52 - Tuberculous meningitis
CS # 52 - Tuberculous meningitisCS # 52 - Tuberculous meningitis
CS# 19 Brain Infarction
Red neurons
CS#19 Brain Infarction
Hemorrhages and necrosis
“gitter cells”
CS #19 Brain infarction
CS # 19. Brain InfarctionCS # 19. Brain Infarction
Brain infarction: Note the many macrophages (“gitter cells”) which are cleaning up the lipid debris from the liquefactive necrosis.
MedulloblastomaMedulloblastoma
Medulloblastoma : located near the midline of the cerebellum and extending into the fourth ventricle above the brainstem
cerebellum
4th V
Brainstem
CS#216 Medulloblastoma
Tumor cells forming rosettes
CS# 216 Medulloblastoma
Small round blue tumor cells
CS# 216 MedulloblastomaCS# 216 Medulloblastoma
Note the following:
1. Small round blue tumor cells forming rosettes in which the cells are concentrically arranged about a central space.
2. Tumor cells have hyperchromatic nuclei which are frequently elongated or crescent (“carrot”) shaped
pseudorosettes
EpendymomaEpendymoma
Tumor arise from the ependymal lining of the fourth ventricle above the brainstem and bulging toward the cerebellum.
cerebellum
CS#218 Ependymoma
Perivascular pseudorosettes
CS#218 Ependymoma
Perivascular pseudorosette
Perivascular pseudo rosette pattern: Tumor cells are arranged about a central vascular space
Vascular space
CS # 218 EPENDYMOMA
Meningioma-GrossMeningioma-Gross
Meningioma : circumscribed reddish-yellow firm neoplasm beneath the dura next to the falx.
CS#248 Meningioma
CS #248: MeningiomaCS #248: Meningioma
Meningioma: benign tumor composed of clusters of pink tumor cells without visible cell membranes
Glioblastoma multiforme (GBM)Glioblastoma multiforme (GBM)
Tumors are quite vascular with prominent areas of necrosis and hemorrhage..
CS# 215 Glioblastoma Multiforme
Marked cellularity with marked hyperchromatism and pleomorphism
CS# 215. Glioblastoma Multiforme
necrosis
Palisading of cells
CS# 215 Glioblastoma Multiforme
Endothelial proliferation
CS: 215: Glioblastoma MultiformeCS: 215: Glioblastoma Multiforme
Glioblastoma multiforme (GBM): Note the following:
1. Marked cellularity with marked hyperchromatism and pleomorphism.
2. Prominent vascularity
3. Area of necrosis at the left with neoplastic cells palisading around it.
#3
Glioblastoma multiforme (GBM).:
#3 Pseudopalisading necrosis of neoplastic cells
necrosis
Pseudopalisading of tumor cells