1
CURRICULUM VITAE
Carol A. Bagnell, Ph.D
Department of Animal Sciences Ph: 848-932-6334; FAX: 732-932-6996
School of Environmental and Biological Sciences [email protected]
Rutgers - The State University of New Jersey http://animalsciences.rutgers.edu/faculty/bagnell
59 Dudley Road – Foran Hall Rm 126
New Brunswick, NJ 08901-8525
EDUCATION
Ph.D 1983 Endocrinology Medical College of Georgia, Augusta, GA
M.S. 1976 Biology West Virginia University, Morgantown, WV
B.A. 1974 Biology Glassboro State College, Glassboro, NJ
PROFESSIONAL EXPERIENCE
2014-present Director, Graduate Program in Endocrinology & Animal Biosciences,
Rutgers University, New Brunswick, NJ
2008-2014 Chair, Dept. of Animal Sciences, Rutgers University
2002- present Professor, Dept. of Animal Sciences, Rutgers University
1995 - 1999 Associate Chair, Dept. of Animal Sciences, Rutgers University
1994 - 2002 Associate Professor, Dept. of Animal Sciences, Rutgers University
1988 - 1989 Visiting Scientist in the laboratory of Dr. Kevin Catt, Endocrinology and
Reproduction Research Branch, NICHD, NIH, Bethesda, MD
1988 – 1994 Assistant Professor, Dept of Animal Sciences, Rutgers University
1987 -1988 Associate Researcher, Pacific Biomedical Research Center (PBRC)/Dept.
of Anatomy and Reproductive Biology, University of Hawaii, Honolulu.
1984 - 1987 Assistant Researcher, PBRC/Dept. of Anatomy and Reproductive
Biology, University of Hawaii; Acting Director, MARC Program
Spring 1983 Visiting Scientist, Institute of Histology and Embryology, University of
Geneva, Switzerland.
1983 - 1984 Postdoctoral Fellow, Dept. of Anatomy and Reproductive Biology and
Dept. of Biochemistry and Biophysics, University of Hawaii
RESEARCH INTERESTS
Studies in my laboratory focus on (1) improving our understanding of maternal programming of
development by testing the lactocrine hypothesis and (2) the role of the hormone relaxin in
reproduction. Our group defined the term ‘lactocrine’ as a means of maternal delivery of milk-borne
bioactive factors into the circulation of offspring as a consequence of nursing. Porcine milk contains
relaxin that is transmitted into the peripheral circulation of neonates only if they are allowed to nurse.
These studies indicate that a window of opportunity for transmission of milk-borne bioactive factors,
including relaxin, from mother to neonate is open during the first few days of life. Data from our
porcine model provide compelling evidence that maternal programming of neonatal female
reproductive tract development requires lactocrine signaling from birth. Current studies focus on the
short-term effects of milk-borne factors on neonatal development as well as the long-term
2
consequences of lactocrine signaling on reproductive health and fertility in adulthood. Since all
mammals evolved to nurse, this research has broad implications for understanding maternal
contributions to postnatal reproductive tract programming in both humans and domestic animals.
GRANT SUPPORT- External
2016-2018 National Institute of Food and Agriculture/US Department of Agriculture:
“Maternal lactocrine programming of female reproductive tract development”,
Funding supplement $554,000, Co-PI with Frank Bartol; ($215,982 to Bagnell).
2013-2017 National Institute of Food and Agriculture/US Department of Agriculture:
“Maternal lactocrine programming of female reproductive tract development”,
$700,000 Co-PI with Frank Bartol; ($325,857 to Bagnell).
2007-2010 US Dept of Agriculture (USDA) Competitive Grants Program: “Molecular
markers and mediators of porcine reproductive tract development”, $343,912 Co-
PI with Frank Bartol, 3-yr renewal; ($152,009 to Bagnell).
2003-2007 USDA Competitive Grants Program: “Molecular markers and mediators of
porcine uterine development”, $297,869 Co-PI with Frank Bartol; ($169,139 to
Bagnell).
1999-2004 USDA Competitive Grants Program: “The role of relaxin in porcine uterine
growth and remodeling”, $180,000 PI.
1993-1997 USDA Competitive Grants Program: "Intraovarian role of relaxin in follicular
development", $239,000 PI.
1993-1995 Johnson & Johnson Discovery Award: "Cell adhesion molecules in the ovary:
Gene expression and immunolocalization", $20,000 PI.
1988-1991 NIH, FIRST Award 1 R29 HD 22885. Paracrine Control of Follicular Growth
and Ovulation", $157,500 PI.
1985-1988 NIH, New Investigator Research Award 1 R23 HD 20624. "Paracrine Control of
Follicular Growth and Ovulation", $107,500 PI.
1984-1985 NIH, NIGMS, MARC program subproject "Production and biological action of
relaxin in the ovarian follicle", $10,434 PI.
GRANT SUPPORT – Internal
USDA/NIFA – Cooperative State Research Service - Hatch Funding
2016-2021 “Role of milk-borne factors in neonatal reproductive tract development”. Project #
3
NJ 06175; $10,000.
2010-2015 “Role of milk-borne factors in neonatal reproductive tract development”. Project #
NJ 06153; $10,000.
2004-2009 “Relaxin and estrogen interaction in porcine cervical development”. $10,000.
2003-2008 “Relaxin and estrogen interaction in porcine cervical development”. $10,000.
1997-2002 “The role of relaxin in control of porcine ovarian development. $10,000.
1993-1996 “Mechanism and nature of the relaxin receptor in the porcine follicle”. $10,000.
1988-1992 “Mechanism and nature of the relaxin receptor in the porcine follicle”. $10,000.
NJ Agriculture Experiment Station - Equine Initiative Funding
2007-2008 “Effects of nutritional supplements on exercise-induced inflammation and
oxidative stress in horses”, Co-PI with C Williams, $33,419
2006-2007 “Development of an exercise-induced joint inflammation model in horses”, Co-PI
with C Williams, $21, 590
2005-2006 “Joint inflammation in horses and cytokine assay development”, Co-PI with C
Williams, $35,000
2004-2005 “Inflammation in horses and cytokine assay development”, Co-PI with K
McKeever, C Williams, P Ryan, $44,000
2002-2004 “Equine relaxin and receptors: Markers of placental function”,
Total (2 awards): $81,000
1995-2002 "Equine relaxin as a diagnostic tool for assessing placental insufficiency and fetal
well-being in the mare", Total (5 awards): $164,834
Other Internal Funding
2004-2006 Busch Biomedical Research Grant: “Tumor suppressor role of epithelial cadherin
in human ovarian cancer”, $25,000
1990-1995 Biomedical Research Support Awards (4), Total: $25,516
1989-1991 Rutgers University Research Council Awards (3), Total: $6,800
RESEARCH SUPPORT - Other
2006-2021 Bernard and Jane Steinetz Research Fund, supported by the Steinetz Charitable
Lead Unitrust for 15 years starting in 2006; ~$65,000/yr; total income to date:
$832,117
2004 Lindstrom Foundation – gift in support of research, $6,000
2003 Novartis, Inc., East Hanover, NJ. Donation of laboratory equipment, estimated
value $45,000
2001-pres Carl N. Steinetz Memorial Fund. Endowment in support of research, ongoing
$111,591
4
TRAINEE SUPPORT – Undergraduate Research
Aresty Undergraduate Research Awards:
2016 Julie Wang: Long term effects of nursing from birth on uterine protein during
pregnancy in the pig; Aresty Research Assistant support
2013 Jessica Lovich: Effects of age and nursing on RXFP1in the neonatal porcine heart;
$1000
2010 Lauren Barron: Influence of nursing on estrogen receptor-alpha and apoptotic-
related proteins in the porcine small intestine; $1000
2010 Kristene Welch: Uterine developmental programming and the impact of lactocrine
signaling; $1000
2009 Nathalie Sanchez: Effects of milk-borne factors on neonatal porcine cardiac
development; $1000
2008 Michael Strug: Role of estrogen and relaxin receptors in increasing mouse
interpubic ligament sensitivity to relaxin; $1000
2007 Megan Dilts: The role of relaxin on connective tissue remodeling and apoptosis in
the neonatal porcine heart and cervix; $1000
Undergraduate Research Fellowships sponsored:
1996- 2001 NJ Commission on Cancer Research Summer Fellowships
1996 "Cell adhesion molecules in cancer cells", $2,800.
1997 "Hormonal control of protease activity in ovarian cancer cells", $2,800.
1999 “Control of MMP activity in NIH-OVCAR ovarian cancer cells”, $2,800
2000 “Mechanism of growth factor action in human ovarian cancer”, $2,800
2001 "Estrogen receptor in growth factor action in ovarian cancer", $2,800
1997-2005 Rutgers University Undergraduate Fellowships (5) Total: $7,500
HONORS/PROFESSIONAL ACTIVITIES
2011 Relaxin 2012 – The 6th International Conference on Relaxin and Relaxin-Related
Peptides, Florence, Italy, Organizing Committee Member
2005 Relaxin 2008 – The 5th International Conference on Relaxin and Relaxin-Related
Peptides, Maui, Hawaii, Organizing Committee Member
2004 Graduate Program Service Award, Department of Animal Sciences, Rutgers
University, New Brunswick, NJ
2003 Distinguished Alumnus Award, Medical College of Georgia School of Graduate
Studies, Augusta, GA
Fall 2001 Sabbatical - Merck Research Laboratories, Rahway, NJ
& 2002 Division of Atherosclerosis and Endocrinology
2000 Relaxin 2004 - The 4th International Conference on Relaxin and Relaxin-Related
Peptides, Organizing Committee Member
5
2002- pres Editorial Board, Reproductive Biology and Endocrinology
2002-2005 Editorial Board, Domestic Animal Endocrinology
1999-2003 Editorial Board, Biology of Reproduction
1996-1997 Sixth Annual ESCOP/ACOP Leadership Development Program, participant
1990-present Reviewer of USDA, NSF, NATO and BARD proposals
1988-present Reviewer, manuscripts submitted to American Journal of Physiology,
Endocrinology, Endocrine Journal and Journal of Endocrinology
PROFESSIONAL SOCIETY MEMBERSHIPS
American Assn for the Advancement of Science
Endocrine Society Society for the Study of Reproduction
Sigma Xi Women in Endocrinology
TEACHING EXPERIENCE
Current Teaching
Animal Reproduction (11:067:327; 3 credits; undergraduate)
Fall semesters 1997 – present (20 yrs); Course Coordinator
125-140 students/year
Animal Microtechniques and Tissue Culture (11:067:067:430; 4 credits; undergraduate)
Spring semesters 1989-present (28 yrs); 30-48 students/year
Upper-level laboratory course team-taught with Drs. Jesse and Uzumcu for students majoring
in Animal Sciences, Biotechnology or Biology
Physiology of Reproduction (16:067:502/16:340:502; 3 credits; graduate)
Course coordinator, 1999; Team-taught course every other year 1991 – 2013
Past Teaching – Undergraduate
Preveterinary Clinical Anatomy (11:067:380; 3 credits) 1989-1996 (7 yrs)
Preveterinary Clinical Anatomy Laboratory (11:067:381; 2 credits)
1989-1996; Upper-level courses intended for preveterinary students; 24 students/year
Animal Science (11:067:142; 3 credits)
1991-1996; First-year, introductory course team-taught with 4 other faculty members;
110 students
6
Animal Nutrition (11:067:330; 3 credits)
Presented one lecture on nutrition and reproduction in 1991 and 1992
Past Teaching – Graduate
Current Principles of Animal Science (16:067:501; 3 credits; 1993)
Recent Advances in Animal Reproduction (16:067:612, 3 credits)
Team-taught with two other faculty, 1994
Graduate Seminar in Animal Sciences (16:067:693; 1 credit) Coordinator, 1993 and 2003
Teaching Grants
1998-1999 Rutgers University Grant. "Conversion of the Biotech Center Storage Room to a
Student Computing Facility for the Biotechnology and Animal Science Curricula
and Library Instruction", $40,000; (Co-PI with Zylstra and Gardner)
1996-1997 Instructional Computing Award Provost's Office. "Animal Science Departmental
Instructional Computing Proposal", $17,578 (C Bagnell, PI; B Jesse, Co-PI).
Funding of a student computing facility in Bartlett Hall.
1995-1996 Teaching Excellence Center Grant, "Production of Instructional Videos for
Veterinary Anatomy", $3,500 (C. Bagnell, PI)
INVITED SEMINAR PRESENTATIONS
A. Keynote or Plenary Addresses
1. 2017: “Lactocrine signaling and developmental programming” - Plenary Lecture. 10th
International Conference on Pig Reproduction, Columbia, MI, June 14, 2017
2. 2014: “Maternal programming of reproductive tract development: The lactocrine
hypothesis” Keynote Lecture. Dept of Physiology & Center for Reproductive Biology
and Health Retreat, Pennsylvania State University, State College, PA, November 7-8,
2014
3. 2012: “Maternal programming of neonatal development”, Russell Nutrition Symposium,
Rutgers University, New Brunswick, NJ, Nov 13, 2012
4. 2012: “Milk-borne relaxin and reproductive system development”, Relaxin 2012- the 6th
International Conference on Relaxin and Related Peptides, Florence, Italy, Oct 7-12, 2012
5. 2012: “Anti-arthritic actions of relaxin, in combination with estrogens, in joint and bone
tissues”, Relaxin 2012- the 6th International Conference on Relaxin and Related Peptides,
Florence, Italy, Oct 7-12, 2012
7
6. 2008: “Milk-borne relaxin and the lactocrine hypothesis for maternal programming of
neonatal tissues”, Relaxin 2008- the 5th International Conference on Relaxin and Related
Peptides, Maui, HI, May 19-23, 2008
7. 2004: “Relaxin and neonatal porcine uterine growth and development”, Relaxin 2004 –
the Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, WY,
September 5-10, 2004
8. 2004: “Relaxin and regulation of porcine uterine development and function”, Plenary
talk, Gordon Research Conference Reproductive Tract Biology, New London, CT
9. 2000: “Relaxin and uterine growth and remodeling”. Relaxin 2000, The 3rd International
Conference on Relaxin and Related Peptides, Broome, Australia
10. 1999: "Relaxin as a biochemical marker of placental insufficiency in the horse".
International Conference on Equine Reproductive Medicine, Celle, Germany
11. 1994: "Porcine relaxin: Gene expression during the cycle and pregnancy". Second
International Congress on the Hormone Relaxin, Adelaide, South Australia
12. 1993: "Sources and biological actions of relaxin in the pig". Plenary talk, 4th International
Conference on Pig Reproduction, Columbia, Missouri
13. 1986: "Paracrine control of follicle development". International Serono Symposium, Paris,
France
B. Other Invited Addresses
1. 2016: “Maternal lactocrine programming of reproductive tract development” Dept of Animal
Sciences, Cornell University, Ithaca, NY
2. 2016:“Role of Nursing from Birth on Reproductive Tract Development”
President’s Research Symposium, Augusta University, Augusta, GA
3. 2013: “Maternal lactocrine programming of neonatal development”, Dept of Dairy Science,
Virginia Polytechnic and State University, Blacksburg, VA, May 7, 2013
4. 2011: “Maternal lactocrine programming of reproductive tract development”, Neonatology
Group, Robert Wood Johnson Medical School, New Brunswick, NJ, November 18, 2011
5. 2009: “Maternal lactocrine programming of reproductive tract development”, Reproductive
Biology Symposium, West Virginia University, Morgantown, WV, July 17, 2009
6. 2008: “Molecular markers and mediators of porcine reproductive tract development: Year 1,
CSREES, USDA National Research Initiative Animal Reproduction Annual Investigator
Meeting. Indianapolis, IN, July 10, 2008
8
7. 2006: “Mechanism of relaxin action in reproduction and beyond”, Department of Animal
Sciences, Rutgers University, New Brunswick, NJ, February, 24, 2006
8. 2004: “Equine relaxin: An insurance policy for pregnant mares”, New York University School
of Medicine, Institute of Environmental Medicine, Tuxedo, NY
9. 2004 “Equine relaxin: An insurance policy for pregnant mares”, 2004 New Jersey State
Agricultural Convention, Long Branch, NJ
10. 2003: “Equine relaxin: An insurance policy for pregnant mares”, Equine Research Update,
Rutgers University, New Brunswick, NJ
11. 2003: “A career in endocrinology: From PhD to Professor”, Medical College of GA,
Augusta, GA
12. 2003: “Relaxin: Mechanism of action and marker of placental function”, Cornell University
Ithaca, NY
13. 2002: "Ovarian gene array studies", Division of Endocrinology and Atherosclerosis, Merck
Research Laboratories, Rahway, NJ
14. 2001: "Relaxin and uterine growth and remodeling", Wyeth Ayerst, Women's Health
Research Institute, Radnor, PA
15. 2001: "Equine relaxin: A diagnostic marker of placental insufficiency" Endocrine Research
Interest Group, Rutgers University/UMDNJ, New Brunswick, NJ
16. 2001: "Relaxin and uterine growth and remodeling", Endocrinology Discovery Group, Merck
Research Laboratories, Rahway, NJ
17. 2001: "Equine relaxin: A tool to diagnose placental insufficiency and monitor fetal well-
being" Dept of Animal Sciences, Rutgers University, New Jersey
18. 2001: “Mechanism of relaxin action in uterine growth & remodeling" Dept. of Animal &
Dairy Science, Mississippi State University, Mississippi
19. 2000: “Mechanism of relaxin action in promoting uterine and cervical growth”. Dept of
Genetics and Molecular Biology, JA Burns School of Medicine, University of Hawaii, HI
20. 1999: "Equine relaxin as a diagnostic tool for placental insufficiency". Danish Veterinary
College, Royal Agricultural and Veterinary University of Copenhagen, Denmark
21. 1999: “Equine relaxin: A tool to diagnose placental insufficiency and monitor treatment
efficacy”. MacDonald College, McGill University, Montreal, Canada
9
22. 1998:“The role of relaxin in reproductive tissue growth”. Dept. of Physiology, University of
Maryland Medical School, Baltimore, MD
23. 1998: “Equine relaxin - Diagnostic marker of placental insufficiency”. Havermeyer
Foundation Workshop on Equine Placentitis, Lexington, KY
24. 1998: “Trophic effects of relaxin: A role for the IGF system”. Symposium on Reproductive
Biology and Hormone Action, Augusta, GA
25. 1998: "Relaxin: Secretion and effects on the IGF system". Dept. of Biomedical Sciences,
University of Guelph, Ontario Canada
26. 1994: "Relaxin in the developing ovarian follicle". Dept. of Biology, Queens College, Flushing,
NY
27. 1993: "The role of relaxin in growth and remodeling of the ovary". Dept. of Obstetrics and
Gynecology, Loeb Medical Research Center, Ottawa, Ontario
28. 1991: "Paracrine control of the ovary: A role for relaxin". Department of Physiology, Cornell
University, Ithaca, NY
29. 1991: "In situ evidence for differential expression of relaxin mRNA by porcine theca
and granulosa lutein cells", Ottawa Civic Hospital, Ottawa, Ontario
30. 1990: "Ovarian relaxin gene expression". Department of Endocrinology and Physiology, Medical
College of Georgia, Augusta, Georgia
31. 1988: "Development of the corpus luteum - Local Control Factors". Department of Anatomy,
Howard University, Washington, D.C.
32. 1985: "A paracrine role for relaxin in ovulation and at parturition". Department of
Obstetrics and Gynecology, School of Medicine, University of Ottawa
GENBANK SUBMISSIONS
Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone
pLGR7s similar to porcine LGR7 (Relaxin receptor). Accession number: CA994861; Short
(284bp) porcine relaxin receptor cDNA; Jan 7, 2003.
Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone
pLGR7l similar to porcine LGR7 (Relaxin receptor). Accession number: CA994862; Long
(431bp) porcine relaxin receptor cDNA; Jan 7, 2003.
Bartol FF, Wiley A, Bathgate RAD, Bagnell CA. Sus scrofa neonatal uterus cDNA clone pLGR8
similar to porcine LGR8 (INSL3 receptor). Accession number: CA997681; Porcine INSL3
(198bp) receptor cDNA; Jan 8, 2003.
10
PUBLICATIONS IN JOURNALS
Refereed, Research Journal Articles
1. George AF, Rahman KM, Camp ME, Prasad N, Bartol FF, Bagnell CA. 2017. Defining
age- and lactocrine-sensitive elements of the neonatal porcine uterine microRNA-mRNA
interactome. Biol Reprod 96(2): 327-340.
2. Ho TY, Rahman KF, Camp ME, Wiley AA, Bartol FF, Bagnell CA. 2016. Timing and
duration of nursing from birth affect neonatal porcine uterine matrix metalloproteinase 9
and tissue inhibitor of metalloproteinase 1. Domestic Animal Endocrinology 59: 1-10.
3. Rahman KM, Camp ME, Prasad N, McNeel AK, Levy SE, Bartol FF, Bagnell CA. 2016.
Age and nursing affect the neonatal porcine uterine transcriptome. Biol Reprod 94(2):46,
1-13.
4. Harvey C, Chen J, Bagnell CA, Uzumcu M. 2015. Methoxychlor and its metabolite
HPTE inhibit cAMP production and expression of estrogen receptors alpha and beta in rat
granulosa cells in vitro. Reproductive Toxicology 51:72-78.
5. Camp ME, Wiley AA, Boulos MB, Rahman KM, Bartol FF, Bagnell CA. 2014. Effects
of age, nursing, and oral IGF1 supplementation on neonatal porcine cervical
development. Reproduction 148: 441-451
6. Rahman KM, Lovich JE, Lam C, Camp ME, Wiley AA, Bartol FF, Bagnell CA. 2014.
Nursing supports neonatal porcine testicular development. Domestic Animal
Endocrinology 48: 84-92.
7. Miller DJ, Wiley AA, Chen JC, Bagnell CA, Bartol FF. 2013. Nursing for 48 h from
birth supports uterine gland development and endometrial cell compartment-specific gene
expression. Biol Reprod 88 (1):4, 1-10.
8. Frankshun A-L, Chen JC, Barron L, Ho T-Y, Miller DJ, Rahman K, Bartol FF, Bagnell
CA. 2012. Nursing during the first two days of life is essential for the expression of
proteins important for growth and remodeling of the neonatal porcine cervix.
Endocrinology 153(9):4511-4521.
9. Chen JC, Frankshun A-L, Wiley AA, Miller DJ, Welch KA, Ho T-Y, Bartol FF, Bagnell
CA. 2011. Relaxin and milk-borne lactocrine-acting factors affect morphoregulatory
gene and protein expression patterns in the neonatal porcine uterus. Reproduction
141:675-683.
10. Ho T-Y, Santora K, Frankshun A-L, Bagnell CA. 2011. Effects of relaxin and estrogens
on bone remodeling markers, receptor activator of NF-kB ligand (RANKL) and
osteoprotegerin (OPG), in rat adjuvant-induced arthritis. Bone 48:1346-1353.
11
11. Frankshun A-L, Ho T-Y, Reimer DC, Chen J, Lasano S, Steinetz BG, Bartol FF, Bagnell
CA. 2011. Characterization and biological activity of relaxin in porcine milk.
Reproduction 141: 373-380.
12. Chen JC, Wiley AA, Ho T-Y, Frankshun A-L, Hord KM, Bartol FF, Bagnell CA. 2010.
Transient estrogen exposure from birth affects uterine expression of developmental
markers in neonatal gilts with lasting consequences in pregnant adults. Reproduction
139:623-630.
13. Lamprecht ED, Bagnell CA, Williams CA. 2009. Inflammatory responses to three
modes of intense exercise in Standardbred mares – a pilot study. Comparative Exercise
Physiology 5: 115-125.
14. Yan W, Chen J, Wiley AA, Bartol FF, Bagnell CA. 2008. Relaxin and estrogen affect
estrogen receptor , vascular endothelial growth factor and relaxin receptor expression in
the neonatal porcine uterus and cervix. Reproduction 135:705-712.
15. Santora K, Rasa C, Visco D, Steinetz BG, Bagnell CA. 2007. Antiarthritic effects of
relaxin, in combination with estrogen, in rat adjuvant-induced arthritis. Journal of
Physiology and Experimental Therapeutics 322(2): 887-893.
16. Ho TY, Yan W, Bagnell CA. 2007. Relaxin-induced matrix metalloproteinase-9
expression is associated with the activation of the NF-kB pathway in human THP-1 cells.
Journal of Leukocyte Biology 81:1303-1310.
17. Masters RA, Crean BD, Yan W, Moss A, Ryan PL, Wiley AA, Bagnell CA, Bartol FF.
2007. Neonatal porcine endometrial development and epithelial proliferation affected by
age and exposure to estrogen and relaxin. Domestic Anim Endocrinol 33: 335-346.
18. Yan W, Wiley AA, Bathgate RAD, Frankshun AL, Lasano S, Crean BD, Steinetz BG,
Bagnell CA, Bartol FF. 2006. Expression of LGR7 and LGR8 by neonatal porcine
uterine tissues and transmission of milk-borne relaxin into the neonatal circulation by
suckling. Endocrinology 147:4303-10.
19. Yan W, Ryan PL, Bartol FF, Bagnell CA. 2006. Uterotrophic effects of relaxin related
to age and estrogen receptor activation in neonatal pigs. Reproduction 131:943-950.
20. Neumann J, Lazaris A, Huang YJ, Karatzas C, Ryan PL, Bagnell CA. 2006. Production
and characterization of recombinant equine prorelaxin. Domestic Animal Endocrinology
31:173-185.
21. Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA. 2002. Relaxin increases
secretion of tissue inhibitor of matrix metalloproteinase-2 and -9 during uterine and
cervical growth and remodeling in the pig. Endocrinology 143:91-98.
22. Ryan PL, Baum DL, Lenhart JA, Ohleth KM, Bagnell CA. 2001. Expression of uterine
12
and cervical epithelial cadherin during relaxin-induced growth in pigs. Reproduction
122:929-937.
23. Lenhart JA, Ryan PL, Ohleth KM, Palmer SS, Bagnell CA. 2001. Relaxin increases
secretion of matrix metalloproteinase-2 and –9 during uterine and cervical growth and
remodeling in the pig. Endocrinology 142:3941-3949.
24. Ryan PL, Bennett-Wimbush K, Vaala WE, Bagnell CA. 2001. Systemic relaxin in
pregnant pony mares grazed on endophyte infected fescue: Effects of fluphenazine
treatment. Theriogenology 56:471-483.
25. Kirkup K, Mallin A, Bagnell CA. 2000. Inhibition of pig granulosa cell adhesion and
growth in vitro by immunoneutralization of epithelial cadherin. J Reprod & Fertility
120:275-281.
26. Lenhart JA, Ryan PL, Ohleth KM, Bagnell CA. 1999. Expression of connexin-26,-32
and -43 gap junction proteins in the porcine cervix and uterus during pregnancy and
relaxin-induced growth. Biol Reprod 61:1452-1459.
27. Ohleth KM, Zhang Q, Lenhart JA, Ryan PL, Bagnell CA. 1999. Trophic effects of
relaxin on reproductive tissue: Role of the IGF system. Steroids 64: 634-639.
28. Ohleth KM and Bagnell CA. 1999. Relaxin secretion and gene expression in porcine
granulosa and theca cells are stimulated during in vitro luteinization. Biol Reprod
60:499-507.
29. Wang-Lee JL, Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1998. Regulation of
urokinase- and tissue-type plasminogen activator by relaxin in the uterus and cervix of the
prepubertal gilt. J Reprod Fertility 114: 119-125.
30. Ohleth KM, Zhang Q, Bagnell CA. 1998. Relaxin protein and gene expression in
ovarian follicles of immature pigs. J Molecular Endocrinology 21:179-187.
31. Lenhart JA, Downey BR, Bagnell CA. 1998. Connexin 43 gap junction protein
expression during follicular development in the porcine ovary. Biol Reprod 58:583-590.
32. Ohleth KM, Lenhart JA, Ryan PL, Radecki SV, Bagnell CA. 1997. Relaxin increases
insulin-like growth factors and IGF binding proteins of the pig uterus in vivo.
Endocrinology 138:3652-3658.
33. Ryan PL, Valentine AF, Bagnell CA. 1996. Expression of E-cadherin in the developing
and adult pig ovary. Biol Reprod 55:1091-1097.
34. Ohleth KM and Bagnell CA. 1995. Relaxin-induced deoxyribonucleic acid synthesis in
porcine granulosa cells is mediated by insulin-like growth factor I. Biol Reprod 53:1286-
1292.
13
35. Zhang Q and Bagnell CA. 1994. Trophic action of relaxin on porcine theca cells:
Interaction with insulin and IGF-I in vitro. Endocrine Journal 2:349-55.
36. Bagnell CA, Zhang Q, Ohleth K, Connor ML, Downey BR, Tsang BK, Ainsworth L.
1993. Developmental expression of the relaxin gene in the porcine corpus luteum. J
Molec Endocrinol 10:87-97.
37. Zhang Q and Bagnell CA. 1993. Relaxin stimulation of porcine granulosa cell
deoxyribonucleic acid synthesis in vitro: Interactions with insulin and insulin-like growth
factor I. Endocrinology 132:1643-1650.
38. Bagnell CA, Tashima L, Tsark W, Ali SM, McMurtry JP. 1990. Relaxin gene
expression in the sow corpus luteum during the cycle, pregnancy and lactation.
Endocrinology 126:2514-2520.
39. Bagnell CA, Tsark W, Tashima L, Downey BR, Tsang BK, Ainsworth L. 1990. Relaxin
gene expression in the porcine follicle during preovulatory development induced by
gonadotrophins. Molecular Endocrinology 5:211-219.
40. Bagnell CA, Baker NK, McMurtry JP, Brocht DM, Lewis GS. 1990. Control of luteal
relaxin release by prostaglandin F2α: Differences in the sow cycle and pregnancy.
Proceedings of the Society for Experimental Biology and Medicine 194:125-130.
41. Bagnell CA, Ayau E, Downey BR, Tsang BK, Ainsworth L. 1989. Localization of
relaxin during formation of the corpus luteum. Biol Reprod 40:835-41.
42. Bagnell CA, Baker NK, McMurtry JP. 1989. Immunohistochemical localization of
insulin in the chick embryo during development. General and Comparative
Endocrinology 73:293-298.
43. Bagnell CA, Frando LB, Downey BR, Tsang BK, Ainsworth L. 1987. Localization of
relaxin in the pig follicle during preovulatory development. Biol Reprod 37:235-40.
44. Bagnell CA, McMurtry JP, Baker NK, Timtim JL, Bryant-Greenwood GD. 1987.
Detection of relaxin by immunohistochemistry in the corpus luteum during lactation.
Biol Reprod 37:1317-1325.
45. Ali SM, McMurtry JP, Bagnell CA, Bryant-Greenwood GD. 1986.
Immunocytochemical localization of relaxin in corpora lutea of sows throughout the
estrous cycle. Biol Reprod 34:139-43.
46. Koay ESC, Bagnell CA, Bryant-Greenwood GD, Lord SB, D'Cruz A, Larkin LH. 1985.
Immunocytochemical localization of relaxin in human decidua and placenta. J Clin Endo
Metab 60:859-63.
47. Bagnell CA, Mills T, Costoff A, Mahesh VB. 1982. A model for the study of androgen
effects on follicular atresia and ovulation. Biol Reprod 27:903-14.
14
Refereed Journal Articles – Reviews
48. Bagnell CA, Ho TY, George AF, Wiley AA, Miller DJ, Bartol FF. 2017. Maternal lactocrine
programming of porcine reproductive tract development. Molec Reprod and Development,
doi: 10.1002/mrd.22815.
49. Bartol FF, Wiley AA, George AF, Miller DJ, Bagnell CA. 2017. Postnatal reproductive
development and the lactocrine hypothesis. J Anim Science 95(5): 2200-2210.
50. Bartol FF, Wiley AA, Miller DJ, Silva AJ, Roberts KE, Davolt MLP, Chen JC,
Frankshun A-L, Camp ME, Rahman KM, Vallet JL, Bagnell CA. 2013. Lactation
Biology Symposium: Lactocrine signaling and developmental programming. Journal of
Animal Science 91:696-705.
51. Bartol FF and Bagnell CA. 2012. Lactocrine programming of female reproductive tract
development: Environmental connections to the reproductive continuum. Mol Cell
Endocrinol 354:16-21.
52. Bagnell CA, Steinetz BG, Bartol FF. 2009. Milk-borne relaxin and the lactocrine
hypothesis for maternal programming of neonatal tissues. Ann N Y Acad Sci 1160:152-
157.
53. Bartol FF, Wiley AA, Bagnell CA. 2009. Relaxin and maternal lactocrine programming
of neonatal uterine development. Ann N Y Acad Sci 1160:158-163.
54. Chen J, Wiley AA, Kauffold H, Wahner M, Bartol FF, Bagnell CA. 2009. Perinatal
zearalenone exposure affects RXFP1, RXFP2 and morphoregulatory gene expression in
the neonatal porcine uterus. Ann N Y Acad Sci 1160: 188-189.
55. Frankshun AL, Ho TY, Steinetz BG, Bartol FF, Bagnell CA. 2009. Biological activity
of relaxin in porcine milk. Ann N Y Acad Sci 1160:164-168.
56. Ho TY, Dilts MA, Bartol FF, Bagnell CA. 2009. Relaxin promotes matrix
metalloproteinase-2 and decreases Wnt/-catenin expression in the neonatal porcine
heart. Ann N Y Acad Sci 1160:287-288.
57. Ryan PL, Christiansen DL, Hopper RM, Bagnell CA, Vaala WE, LeBlanc MM. 2009.
evaluation of systemic relaxin blood profiles in horses as a means of assessing placental
function in high-risk pregnancies and responsiveness to therapeutic strategies. Ann NY
Acad Sci 1160: 169-178.
58. Wiley AA, Kauffold J, Wähner M, Crean-Harris B, Miller D, Bagnell CA, Bartol FF.
2009. Laser microdissection of neonatal porcine endometrium for tissue specific
evaluation of relaxin receptor (RXFP1) expression in response to perinatal zearalenone
exposure. Ann N Y Acad Sci 1160:190-191.
59. Yan W, Wiley, AA, Bartol FF and Bagnell CA. 2005. Tissue-specific effects of relaxin
15
on the reproductive tract of neonatal gilts. Ann N Y Acad Sci. 1041:132-5.
60. Bagnell CA, Yan W, Wiley AA, Bartol FF. 2005. Effects of relaxin on neonatal porcine
uterine growth and development. Ann N Y Acad Sci. 1041:248-55.
61. Ho TY and Bagnell CA. 2005. Relaxin induces matrix metalloproteinase-9 through
activation of nuclear factor kappa B in human THP-1 cells. Ann N Y Acad Sci.
1041:314-6.
62. Santora K, Rasa C, Ronan J, Visco D, Steinetz B, Bagnell CA. 2005. Effects of relaxin in
a model of rat adjuvant-induced arthritis. Ann N Y Acad Sci. 1041:481-5.
63. Ryan PL, Bennet-Wimbush K, Vaala W, Bagnell CA. 1999. Relaxin as a biochemical
marker of placental insufficiency in the horse: a review. Pferdeheilkunde (Equine Health)
15: 622-626.
64. Bagnell CA, Zhang Q, Downey BR, Ainsworth L. 1993. Sources and biological actions
of relaxin in the pig. J Reprod Fert Suppl 48:127-138.
65. Bagnell CA. 1991. Production and biologic action of relaxin within the ovarian follicle:
An Overview. Steroids 56:242-246.
66. Mahesh VB, Mills TM, Bagnell CA, Conway BA. 1987. Animal models for study of
polycystic ovaries and ovarian atresia. Advances in Expt Medicine and Biology 219:
237-257.
67. Gambrell R, Bagnell CA, Greenblatt R. 1983. Role of estrogens and progesterone in the
etiology and prevention of endometrial cancer. Am J Obstet and Gynecol 146(6): 696-
707.
PUBLICATIONS IN BOOKS
1. Bartol FF, Wiley AA, Bagnell CA. 2008. Epigenetic programming of porcine
endometrial function and the lactocrine hypothesis. Reprod Dom Anim (July) 43(2): 281-
287.
2. Bartol FF, Wiley AA, Bagnell CA. 2006. Uterine development and endometrial
programming. Soc Reprod Fertil Suppl 62:113-130.
3. Lenhart J, Ohleth K, Ryan P , Wang-Lee J, Bagnell CA. 2001. Relaxin and porcine
uterine growth and remodeling. In: Relaxin 2000 edited by GW Tregear, R Ivell, RA
Bathgate and JD Wade, Kluwer Scientific Publishers, Netherlands, pp 83-89.
4. Ryan PL, Bennett-Wimbush K, Vaala WE, Bagnell CA. 2001. Relaxin and placental
dysfunction in the horse. In: Relaxin 2000 edited by GW Tregear, R Ivell, RA Bathgate
and JD Wade, Kluwer Scientific Publishers, Netherlands, pp. 91-99.
16
5. Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1999. Effect of relaxin on
tissue inhibitor of metalloproteinase-1 and -2 in the porcine uterus and cervix. In: RA
Greenwald, S Zuker, LM Golub (eds). Inhibition of Matrix Metalloproteinases:
Therapeutic Applications, Annals of the NY Acad of Sciences Vol 878: 565-566.
6. Bagnell CA. 1995. Porcine relaxin: Gene expression during the cycle and pregnancy.
In: A MacLennan, G. Tregear G.D. Bryant-Greenwood (eds). Progress in Relaxin
Research. World Scientific Publishing Co., Singapore pp. 93-100.
7. Bagnell CA, Ohleth K, Clark CL, Taylor MJ. 1993. Detection of relaxin secretion and
gene expression in individual porcine luteal cells. In: P.C.K. Leung, A.J.W. Hsueh, and
H.G. Friesen (eds). Molecular Basis of Reproductive Endocrinology. Springer-Verlag,
NY, pp. 264-269.
8. Bagnell CA, Ainsworth L, Bryant-Greenwood GD, Greenwood FC. 1987. Follicular
relaxin: A role in the paracrine control of ovarian function. In: F. Naftolin, A.
DeCherney (eds). The Control of Follicle Development, Ovulation and Luteal Function:
Lessons from In Vitro Fertilization. Raven Press, NY, pp. 35-44.
9. Bagnell CA, McMurtry JP, Lewis GS. 1987. The effect of prostaglandin F on relaxin
release differs in the cyclic and pregnant sow. In: V.B. Mahesh, D.S. Dhinsa, E.
Anderson, S.P. Kalra (eds). Regulation of Ovarian and Testicular Function. Plenum
Press, NY, pp. 715-719.
10. Bagnell CA, Greenwood FC, Bryant-Greenwood GD. 1984. A paracrine role for
follicular relaxin. In: M.R. Sairam and L.E. Atkinson (eds). Gonadal Proteins and
Peptides and Their Biological Significance. World Scientific Publ. Co, Singapore, pp.
299-308.
11. Mahesh VB, Costoff A, Mills T, Bagnell CA. 1982. The polycystic ovary syndrome and
experimental models for the study of its pathogenesis. In: T. Muldoon, V. Mahesh, B.
Perez-Ballester (eds). Recent Advances in Fertility Research, Part A: Developments in
Reproductive Endocrinology. Alan R. Liss, NY, pp. 301.
PUBLICATIONS – in press/ in preparation
George AF and Bagnell CA. 2017. Relaxin. In: M Skinner (ed). Encyclopedia of Reproduction,
2nd Edition, Volume 2, Female Reproduction - Pregnancy, Chapter 91. Elsevier Inc., Waltham,
MA, in press.
George AF, Rahman KM, Miller DJ, Wiley AA, Camp M, Bartol FF, Bagnell CA. Effects of
colostrum, feeding method and oral IGF1 on porcine uterine development. In review in
Reproduction.
George AF, Prasad N, Keel B, Vallet JA, Bartol FF, Bagnell CA. Long-term effects of nursing
on the uterine porcine transcriptome at pregnancy day 13. In preparation.
17
George AF, Vallet JA, Bartol FF, Bagnell CA. Long-term effects of lactocrine deficiency on
proteomic analysis of porcine uterine secretions in early pregnancy. In preparation.
ABSTRACTS
Gray KK, Wiley AA, Miller DJ, Vallet JL, Bagnell CA, Bartol FF. 2017. Lactocrine-deficient
gilts exhibit altered patterns of endometrial development on postnatal day 14. 50th Meeting of
the Society for the Study of Reproduction, Washington, DC, July 2017.
George AF, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2017. Nursing for 12 hours from
birth supports neonatal porcine uterine development. 50th Meeting of the Society for the Study of
Reproduction, Washington, DC, July 2017.
George AF, Rahman KM, Camp ME, Prasad N, Bartol FF, Bagnell CA. 2016. Integrated
microRNA-mRNA expression profiling by next generation sequencing reveals age- and
lactocrine-sensitive biological processes in the neonatal porcine uterus. 49th Meeting of the
Society for the Study of Reproduction, San Diego, CA, July 2016.
George AF, Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Colostrum, oral
insulin-like growth factor-1, and pregnant sow serum support neonatal porcine uterine cell
proliferation. 48th Annual Meeting of the Society for the Study of Reproduction, San Juan, PR,
June 2015.
Selected for a 2015 USDA NRI AFRI Merit Award
Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Defining the age-sensitive
neonatal porcine uterine transcriptome. 48th Annual Meeting of the Society for the Study of
Reproduction, San Juan, PR, June 2015.
Ho T, Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2015. Timing of colostrum
consumption and duration of nursing from birth affect neonatal porcine uterine and cervical
MMP9 and TIMP1 expression. 48th Annual Meeting of the Society for the Study of
Reproduction, San Juan, PR, June 2015.
Camp ME, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2014. Colostrum and oral insulin-
like growth factor-1 support neonatal porcine cervical proliferation and development. 47th
Annual Meeting of the Society for the Study of Reproduction, Grand Rapids, MI, July 2014.
Rahman KM, Camp ME, Prasad N3, McNeel AK, Levy SK, Bartol FF, Bagnell CA. 2014.
Defining the lactocrine-sensitive neonatal porcine uterine transcriptome. 47th Annual Meeting of
the Society for the Study of Reproduction, Grand Rapids, MI, July 2014.
Camp ME, Boulos MB, Wiley AA, Rahman KM, Bartol FF, Bagnell CA. 2013. Lactocrine
effects on porcine cervical histoarchitecture and cell proliferation. 46th Annual Meeting of the
Society for the Study of Reproduction, Palais de Congress, Montreal, Canada, July 22-26, 2013
18
Rahman KM, Lovich JE, Lam C, Camp ME, Bartol FF, Bagnell CA. 2013. Nursing supports
neonatal porcine testicular development: Lactocrine effects on Sertoli cell number and
proliferation. 46th Annual Meeting of the Society for the Study of Reproduction, Palais de
Congress, Montreal, Canada, July 22-26, 2013
Oral presentation selected for an SSR Agricultural Fellowship Award
Roberts KE, Davolt ML, Miller DJ, Wiley AA, Bagnell CA, Bartol FF. 2013. Identification of
cell compartment-specific gene expression events associated with estrogen receptor-alpha
dependent endometrial development using multispectral imaging and digital image processing.
46th Annual Meeting of the Society for the Study of Reproduction, Palais de Congress, Montreal,
Canada, July 22-26, 2013
Uczkowski HM, Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. The effects of nursing
on expression of estrogen receptor alpha in the neonatal porcine brain. University of Sao Paulo,
Faculty of Food Engineering and Animal Science, 20th International Symposium of
Undergraduate Research, Sao Paulo, Brazil, Oct, 2012.
Uczkowski HM, Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. Importance of nursing
for estrogen receptor-alpha expression in the neonatal porcine cerebral cortex and hypothalamus.
Annual Meeting of the Society for the Study of Reproduction, Penn State U, PA, August 12-15.
Rahman KM, Chen JC, Camp ME, Bartol FF, Bagnell CA. 2012. Nursing supports expression of
proteins associated with neonatal porcine testicular development. Annual Meeting of the Society
for the Study of Reproduction, Penn State U, PA, August 12-15.
Camp ME, Rahman KM, Bartol FF, Bagnell CA. 2012. A neonatal porcine bioassay for
identification of lactocrine activity in colostrum. Annual Meeting of the Society for the Study of
Reproduction, Penn State U, PA, August 12-15.
Camp ME, Ferio KM, Chen JC, Welch KM, Bartol FF, Bagnell CA. 2011. Defining a Critical
Time Period for Lactocrine Signaling in Support of Neonatal Porcine Cervical Development.
Annual Meeting of the Society for the Study of Reproduction, Portland, OR, July 31-August 4.
Ferio KM, Chen JC, Welch KA, Camp ME, Bartol FF, Bagnell CA. 2011. Age and Duration-
Dependent Effects of Lactocrine Signaling on Markers and Mediators of Uterine Growth and
Remodeling in Neonatal Gilts. Annual Meeting of the Society for the Study of Reproduction,
Portland, OR, July 31-August 4.
Miller DJ, Silva AJ, Wiley AA, Bagnell CA, Bartol FF. 2011. Nursing for 48 h from birth
supports normal Tissue compartment-specific gene expression events and neonatal porcine
endometrial morphogenesis. Annual Meeting of the Society for the Study of Reproduction,
Portland, OR, July 31-August 4.
Selected for a 2011 USDA NRI CSREES Merit Award
Bartol FF, Chen JC, Miller DJ, Frankshun A-L, Wiley AA, Silva AJ, Camp ME, Ferio KM,
Bagnell CA. 2011. The lactocrine hypothesis: Programming reproductive tract development.
Triennial Lactation Symposium (In honor of Dr. Alan Tucker) 2011 ADSA/ASAS Joint Annual
19
Meeting, July 10-14, New Orleans, LA.
Barron LA, Frankshun A-L, Bartol FF, Bagnell CA. 2011. Influence of nursing on estrogen
receptor α and apoptotic-related proteins in the porcine small intestine. SEBS Undergraduate
Research Symposium, Cook Campus, Rutgers University, April 2011.
First prize – 2011 SEBS Undergraduate Research Poster Competition
Bartol FF, Chen JC, Miller DJ, Frankshun A-L, Wiley AA, Silva AJ, Camp ME, Ferio KM,
Bagnell CA. 2011. The lactocrine hypothesis: Programming reproductive tract development. J
Anim Sci 89 (E-Suppl 1):1 (Abstract 3).
Bartol FF, Bagnell CA. 2010. Programming reproductive tract development. J. Anim. Sci. Vol.
88, E-Suppl. 2, P.793 (Abst 917)
Barron LA, Frankshun A-L, Bartol FF, Bagnell CA. 2010. Influence of nursing on markers of
apoptosis in the neonatal porcine small intestine. University of Sao Paulo, Faculty of Food
Engineering and Animal Science, 18th International Symposium of Undergraduate Research, Sao
Paulo, Brazil, Nov, 2010.
Welch KA, Chen J, Frankshun A-L, Bartol FF, Bagnell CA. 2010. The role of milk-borne
factors on matrix metalloproteinase (MMP) 9 protein and gene expression in the neonatal porcine
uterus. University of Sao Paulo, Faculty of Food Engineering and Animal Science, 18th
International Symposium of Undergraduate Research, Sao Paulo, Brazil, Nov, 2010.
Chen JC, Frankshun A-L, Welch KA, Ferio KM, Wiley AA, Ho T-Y, Bartol FF, Bagnell CA.
2010. Lactocrine signaling supports matrix metalloproteinase (MMP) 9 expression in the
neonatal porcine uterus. Annual Meeting of the Society for the Study of Reproduction,
Milwaukee, WI, July 30-August 3.
Selected for a 2010 USDA NRI CSREES Merit Award
Ferio KM, Frankshun A-L, Chen JC, Ho T-Y, Miller DJ, Bartol FF, Bagnell CA. 2010.
Colostrum is important for estrogen receptor- expression in male and female neonatal porcine
reproductive tissues. Annual Meeting of the Society for the Study of Reproduction, Milwaukee,
WI, July 30-August 3.
Frankshun A-L, Chen JC, Barron LA, Ferio KM, Miller DJ, Bartol FF, Bagnell CA. 2010.
Nursing during the first 48 h of life is important for expression of proteins involved in neonatal
porcine cervical development at postnatal day 14. Annual Meeting of the Society for the Study of
Reproduction, Milwaukee, WI, July 30-August 3.
Sanchez N, Chen JC, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2010. Effects of lactocrine
signaling and relaxin on estrogen and relaxin receptor expression in the neonatal porcine heart.
Annual Meeting of the Society for the Study of Reproduction, Milwaukee, WI, July 30-August 3.
Silva AJ, Wiley AA, Frankshun A-L, Bagnell CA, Bartol FF. 2010. Defining the porcine milk
proteome. Annual Meeting of the Society for the Study of Reproduction, Milwaukee, WI, July
30-August 3.
20
Welch KA, Chen JC, Frankshun A-L, Bartol FF, Bagnell CA. 2010. The role of milk-borne
factors on matrix metalloproteinase (MMP) 9 expression in the neonatal porcine uterus. SEBS
Undergraduate Research Symposium, Cook Campus, Rutgers University, April 2010.
First prize – 2010 SEBS Undergraduate Research Poster Competition
Sanchez N, Chen JC, Miller DJ, Wiley AA, Bartol FF, Bagnell CA. 2009. The effects of milk-borne
factors on estrogen receptor expression in the neonatal porcine heart. University of Sao Paulo,
Faculty of Food Engineering and Animal Science, 17th International Symposium of Undergraduate
Research, Sao Paulo Brazil, Nov 3, 2009
Chen JC, Frankshun A-F, Wiley AA, Miller DJ, Welch KA, Ho T-Y, Bartol FF, Bagnell CA.
2009. Relaxin and milk-borne lactocrine-acting factors affect morphoregulatory gene expression
patterns in the neonatal porcine uterus. Annual Meeting of the Society for the Study of
Reproduction, Pittsburgh, Pennsylvania, July 18-21.
Frankshun A-L, Chen JC, Miller DJ, Wiley AA, Ho T-Y, Bartol FF, Bagnell CA. 2009. Milk
and relaxin affect expression of proteins important for growth, remodeling and apoptosis of the
neonatal porcine cervix. Annual Meeting of the Society for the Study of Reproduction,
Pittsburgh, Pennsylvania, July 18-21.
Strug M, Frankshun A-L, O’Byrne E, Lasano S, Steinetz BG, Bagnell CA. 2009. Development
of prepubertal mouse interpubic joint sensitivity to estrogen and relaxin. Annual Meeting of the
Society for the Study of Reproduction, Pittsburgh, Pennsylvania, July 18-21.
Strug M., Frankshun A.L., Lasano S., Steinetz B.G., Bagnell C.A. 2008. Role of estrogen and
relaxin receptors in increasing neonatal mouse interpubic ligament sensitivity to relaxin.
University of Sao Paulo, Faculty of Food Engineering and Animal Science, 16th International
Symposium of Undergraduate Research, Sao Paulo Brazil, Nov 3, 2008
Frankshun A, Steinetz B, Bartol FF, Bagnell CA. 2008. Characterization and biological activity of
milk-borne relaxin. Gordon Research Conference on Reproductive Tract Biology, Andover, NH,
Aug 3-8.
Chen J, Wiley AA, Kauffold H, Wahner M, Bartol FF, Bagnell CA. 2008. Perinatal
zearalenone exposure affects RXFP1, RXFP2 and morphoregulatory gene expression in the
neonatal porcine uterus. Gordon Research Conference on Reproductive Tract Biology, Andover,
NH, Aug 3-8.
Lamprecht, ED, Bagnell CA, Williams CA. 2008. Effect of exercise and superoxide dismutase
on systemic antioxidants and nitric oxide in horses. Am. Soc. Anim Sci Proc 86.
Naftolovich R, Ho TY, Frankshun AL, Chen J, Bagnell CA. 2007. In vitro effects of relaxin on
matrix metalloproteinase-2 expression and activity in the porcine neonatal heart. University of
Sao Paulo, Faculty of Food Engineering and Animal Science, 15th International Symposium of
Undergraduate Research, Sao Paulo, Brazil, Nov 28-29, 2007.
21
Chen J, Frankshun A, Ho T, Bartol FF, Bagnell CA. 2007 Estrogen exposure from birth affects
uterine gene expression in neonatal gilts that persists in pregnant adults. 40th Annual Meeting of
the Society for the Study of Reproduction, San Antonio, TX, July 21-25, 2007.
Lamprecht ED, Bagnell CA, Williams CA. 2007. Inflammatory responses to three modes of
intense exercise in Standardbred mares. Equine Science Society Proceedings 20: 76-77.
Crean BD, Masters RA, Yan W, Wiley AA, Bagnell CA, Bartol FF. 2006 Porcine uterine
expression of MSX1 and MSX2: Effects of relaxin, estrogen and ICI 182,780 in the neonatal
endometrium. 39th Annual Meeting of the Society for the Study of Reproduction, Omaha, NE,
July 27-Aug 1, 2006.
Ho T, Santora K, Yan W, Visco D, Bagnell CA. 2006 Relaxin and estrogen regulate the bone
remodeling markers, receptor activator of nuclear factor-kappa B ligand (RANKL) and
osteoprotegerin (OPG) in rat adjuvant-induced arthritis. 39th Annual Meeting of the Society for
the Study of Reproduction, Omaha, NE, July 27-Aug 1, 2006.
Ho T, Yan W, Wiley AA, Bartol FF, Bagnell CA. 2005 Evolution of the Hoxa/Wnt Axis and
estrogen regulation of Wnt7a expression in the neonatal porcine uterus. 38th Annual Meeting of
the Society for the Study of Reproduction, Quebec, Canada, July 24-27.
Santora K, O’Byrne E, Visco D, Steinetz BG, Bagnell CA. 2005. Relaxin decreases tumor
necrosis factor in chronic and acute rat models of joint inflammation. 38th Annual Meeting of
the Society for the Study of Reproduction, Quebec, Canada, July 24-27.
Yan W, Lasano S, Steinetz BG, Bartol FF, Bagnell CA. 2005. Presence of relaxin in the milk of
lactating sows and its transmission to neonatal pigs via suckling. 38th Annual Meeting of the
Society for the Study of Reproduction, Quebec, Canada, July 24-27.
Masters RA, Crean BD, Yan W, Wiley AA, Bagnell CA, Bartol FF. 2005. Distribution of active
beta-catenin in neonatal porcine uterine tissues affected by age and exposure to estrogen and relaxin.
38th Annual Meeting of the Society for the Study of Reproduction, Quebec, Canada, July 24-27.
Yan W, Wiley AA, Bartol FF, Bagnell CA. 2004. Tissue-specific response to relaxin in the
reproductive tract of neonatal gilts: LGR7 expression and regulation by relaxin. Relaxin 2004 –
the Fourth International Conference on Relaxin and Related Peptides, Jackson Hole, WY,
September 5-10, 2004.
Santora K, Rasa C, Ronan J, Visco D, Steinetz B, Bagnell CA. 2004. Effects of relaxin in a
model of rat adjuvant-induced arthritis. Relaxin 2004 – the Fourth International Conference on
Relaxin and Related Peptides, Jackson Hole, WY, September 5-10, 2004.
Ho TY, Bagnell CA. 2004. Relaxin induces matrix metalloproteinase-9 through activation of
nuclear factor kappa B in human THP-1 cells. Relaxin 2004 – the Fourth International
Conference on Relaxin and Related Peptides, Jackson Hole, WY, September 5-10, 2004.
22
Yan W, Wiley, AA, Bartol FF, Bagnell CA. 2004. Tissue-specific response to relaxin in the
reproductive tract of neonatal gilts: LGR7 expression and regulation by relaxin. Gordon
Research Conference – Reproductive Tract Biology, June 6-11, 2004, New London, CT.
Yan W, Bagnell CA. 2003. Effects of relaxin on estrogen receptor and vascular endothelial growth
factor expression in the cervix and vagina of neonatal pigs. Soc for Theriogenology, Sept 16 –20,
2003, Columbus, OH.
Wiley A, Bartol FF, Bathgate RA, Bagnell CA. 2003. Relaxin (LGR7) and insulin-like peptide-3
(LGR8) receptor expression in neonatal porcine uterine tissues. Biol Reprod 68(1): 156.
Yan W, Ryan PL, Bagnell CA. 2002. Tissue-specific effects of relaxin on the reproductive tract of
neonatal pigs: Estrogen receptor-dependent and independent actions. Biol Reprod 66(1): 202.
Neumann J, Liu SW, Bagnell CA. 2002. Relaxin increases vascular endothelial growth factor
production through a cAMP-dependent mechanism in the human monocyte cell line, THP-1.
Biol Reprod 66(1): 200.
Bagnell CA, Neumann J, Ryan PL. 2002. Equine relaxin: A diagnostic marker of placental
insufficiency and fetal well-being. Advances in Therapeutic Agents Discovery and
Development, January 29, Rutgers University, New Brunswick, NJ.
Neumann J, Huang Y-J, Ryan PL, Bagnell CA. 2001. Production and characterization of
recombinant equine relaxin. Biol Reprod 64(1): 599.
Malkiewicz S, Bagnell CA. 2001. Mechanism of growth factor action in an ovarian cancer cell
line. Rutgers Undergraduate Fellows Program, April 25, Rutgers University, New Brunswick,
NJ.
Neumann J, Huang Y-J, Bagnell CA. 2000. Strategies for the production of recombinant equine
relaxin. Equine Research Update, Dec 9, Rutgers University, New Brunswick, NJ.
Ryan P, Vaala W, Bagnell CA. 2000. Relaxin and placental dysfunction in the horse. Relaxin
2000 – 3rd International Meeting on relaxin and relaxin-like peptides. Oct 22-27, Broome,
Australia.
Lenhart JA, French KA, Bagnell CA. 2000. Effect of relaxin on vascular endothelial growth
factor in the porcine uterus and cervix. Biol Reprod 62 (1):492.
Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 2000. Matrix metalloproteinase-2 in
the porcine uterus and cervix: Effects of relaxin. 21st Century Workshop on Animal
Biotechnology, April 7, Rutgers University, New Brunswick, NJ.
Lenhart JA, Ryan PL, Ohleth KM, Bagnell CA. 1999. Differential expression of connexin-26, -
32 and -43 gap junction proteins in the porcine cervix during relaxin-induced growth and
remodeling. Biol Reprod 60 (1): 250.
23
Ryan P, Bennet-Wimbush K, Loch W, Vaala W, Bagnell CA. 1998. Effects of fescue toxicosis
and fluphenazine on relaxin concentrations in pregnant pony mares. American Association of
Equine Practitioners Proceedings 44: 60-61.
Ryan P, Vaala W, Bagnell CA. 1998. Evidence the equine relaxin in a good indicator of
placental insufficiency in the mare. AAEP Proceedings 44: 62-63.
Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1998. Effect of relaxin on tissue
inhibitor of metalloproteinase (MMP)-1 and -2 in the porcine uterus and cervix. NY Academy of
Sciences Conference, Inhibition of MMPs: Therapeutic Applications, Tampa, FL.
McGonigle KM, Lenhart JA, McConochie RM, Bagnell CA. 1998. Effects of relaxin on the
porcine granulosa cell matrix metalloproteinase system. XII Ovarian Workshop, Houston, TX.
Lenhart JA, Ohleth KM, Ryan PL, Palmer SS, Bagnell CA. 1998. Effect of relaxin on matrix
metalloproteinase-2 in the porcine uterus and cervix. Biol Reprod 58 (1):326.
Kirkup KM and Bagnell CA. 1998. Immunoneutralization of epithelial cadherin inhibits
porcine granulosa cell DNA synthesis. Biol Reprod 58 (1):33.
Lenhart JA, McGonigle KM, Ohleth KM, Ryan PL, Bagnell CA.1997. Matrix metalloproteinase
activity is modulated by relaxin in porcine granulosa cells and the uterus. Biol Reprod 56(1):209.
Ohleth KM and Bagnell CA. 1997. Relaxin secretion from porcine theca and granulosa cells is
stimulated by in vitro luteinization. Biol Reprod 56(1):253.
Ryan PL, Vaala WE, Bagnell CA. 1997. Equine relaxin: Hormonal measurement of placental
insufficiency in the at-risk pregnant mare. Biol Reprod 56(1):437.
Ryan PL, Vaala WE, Bagnell CA. 1997. Equine relaxin: A diagnostic tool for assessing at risk
pregnancies and parturient complications in the mare. 15th Equine Nutrition and Physiology
Symposium, Fort Worth, Texas, May 29-31, 1997.
Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1996. Connexin 43 gap junction expression
increases in the porcine cervix and uterus during relaxin-induced growth and remodeling. Biol
Reprod 54(1):250.
Lenhart JA, Ohleth KM, Ryan PL, Bagnell CA. 1996. The effect of relaxin in vivo on porcine
ovarian follicular fluid proteoglycan levels and matrix metalloproteinases. XIth Ovarian
Workshop, London, Ontario.
Ohleth KM, Lenhart JA, Ryan PL, Bagnell CA. 1996. Effect of relaxin on the porcine uterine
insulin-like growth factor system in vivo. Biol Reprod 54(1):291.
Ryan PL, Baum DL, Lenhart JA, Ohleth KM, Bagnell CA. 1996. Relaxin regulates epithelial
cadherin expression in porcine reproductive tissue in vivo. Biol Reprod 54(1):547.
24
Lenhart JA, Bagnell CA. 1995. Localization of connexin 43 gap junction protein during
follicular development in the porcine ovary. Biol Reprod 52(1):101.
Ohleth KM and Bagnell CA. 1995. Expression of E-cadherin in the developing and adult pig
ovary. Biol Reprod 52(1):146.
Ohleth KM, Bagnell CA. 1994. Effect of relaxin on IGF-I secretion by cultured porcine
granulosa cells. Biol Reprod 50(1):273.
Zhang Q, Bagnell CA. 1994. Relaxin induction of tyrosine phosphorylation in porcine granulosa
cells. Biol Reprod 50(1):108.
Ohleth KM, Bagnell CA. 1993. A relaxin-like protein in the avian ovary. Biol Reprod 48(1):93.
Zhang Q, Bagnell CA. 1993. Effect of tyrosine kinase inhibitors on relaxin-induced DNA
synthesis in cultured porcine granulosa cells. Biol Reprod 48(1):493.
Zhang Q, Bagnell, CA. 1993. Autocrine action of relaxin on porcine theca interna cell DNA
synthesis: Interactions with hormones of the insulin-like family in vitro. Presented at the Fourth
International Conference on Pig Reproduction, Columbia, Missouri.
Bagnell CA, Feldman MR, Ohleth KM, Blaschuk O, Ainsworth L. 1992. The
immunohistochemical localization of clusterin in the developing porcine ovary. Biol Reprod
46(1):216.
Zhang, Q, Ohleth KM, Bagnell CA. 1992. Biological action of relaxin in the developing pig
follicle: Effects on cell proliferation and deoxyribonucleic acid (DNA) synthesis in vitro. Biol
Reprod 46(1):217.
Bagnell CA, Zhang Q, Ohleth K, Downey BR, Ainsworth L. 1991. Developmental expression
of the relaxin gene in the porcine corpus luteum. Biol Reprod 44(1):189.
Bagnell CA, Ohleth K, Clark CL, Taylor MT. 1991. Simultaneous detection of relaxin
secretion and gene expression in individual porcine luteal cells. Presented at the Serono
Symposium "Molecular Basis of Reproductive Endocrinology" in Vancouver, British Columbia.
Bagnell CA. 1990. Identification of immunoreactive relaxin in the neurohypophysis of the pig.
Biol Reprod 42(1):184.
Bagnell CA, Tsark W, Tashima L, Downey BR, Tsang BK, Ainsworth L. 1989. Relaxin gene
expression during ovarian follicular development in the pig. 71st Annual Meeting of the
Endocrine Society, Seattle, Washington, p 205.
Bagnell CA, Ali SM, McMurtry JP. 1988. In situ localization of relaxin messenger RNA in the
pig corpus luteum in the cycle, pregnancy and lactation. Biol Reprod 38(1):179.
25
Bagnell CA, Ayau E, Downey BR, Tsang BK, Ainsworth L. 1988. Localization of relaxin
during formation of the corpus luteum. Presented at the 1988 Ovarian Workshop in Tacoma,
Washington.
Bagnell CA, Frando LB, Bryant-Greenwood GD, Downey BR, Tsang BK, Ainsworth, L. 1986.
Localization of relaxin in the pig follicle during preovulatory development. Biol Reprod
34(1):16.
Bagnell CA, Greenwood FC, Bryant-Greenwood GD. 1985. Paracrine relaxin: A role in the
ovarian follicle of the pig and rat. J. Endocrinology 107S:141.
Bagnell CA, Baker NK, Bryant-Greenwood GD. 1985. Immunohistochemical localization of
relaxin in the rat ovary during lactation. Biol Reprod 32(1):90.
Bryant-Greenwood GD, Bagnell CA, Koay ESC, Greenwood FC. 1984. Paracrine role for
follicular and decidual relaxins. Presentation of paper at Montebello Symposium on Gonadal
Proteins and Peptides, Montebello, Canada.
Bagnell CA, Bryant-Greenwood GD. 1984. Plasminogen activator during follicular
development in rat and pig granulosa cells. Presented at the 5th Biennial Ovarian Workshop,
1984, Laramie, Wyoming.
Bagnell CA, Mills T, Stadt H, Gerardot R, Mahesh VB. 1983. Inhibition of Aromatase: A
possible mechanism of androgen-induced atresia. Presented at the 65th Annual Endocrine
Society Meeting, San Antonio, Texas.
Bagnell CA, Mills T, Costoff A, Mahesh, VB 1982. Comparison of histology and ovulation as
measures of ovarian function using a rat model developed to study follicular growth and atresia.
Presented at the Annual Meeting of the Society for Experimental Biology and Medicine,
Southeastern Section, Augusta, GA.
Bagnell CA, Mills T, Costoff A, Mahesh VB. 1981. A model for the study of androgen effects
on follicular atresia. Southeastern Meeting of Endocrinology, Emory University, Atlanta, GA.
POSTDOCTORAL FELLOWS and STUDENTS MENTORED
Dr. Peter Ryan, Postdoctoral Fellow, 1994-1997
Present address: Professor, Dept of Animal & Dairy Science, Mississippi State U.
Dr. Frank Petersen, Research Associate, 2004-2006
Present address: NJ Dept of Agriculture, Division of Animal Health, Trenton, NJ
Dr.Teh-Yuan Ho, Postdoctoral Fellow, 2003-2004; Research Associate 2005-present
26
Graduate students – Primary advisor (current location in parentheses):
Student Yrs Deg Project/Thesis Title
Ashley George 2013 - Ph.D. Role of nursing in maternal programming of
neonatal uterine development
Meredith Camp 2009-2014 Ph.D. Lactocrine signaling and neonatal porcine
reproductive tract development
(Food and Drug Administration, Washington, DC)
Henry Bignell 2011-2014 M.S. Glutamine supplementation on the lipid profile of
colostrum, milk and neonatal adipose tissue
(Cornell University, County Agent)
Kathleen Rahman 2008-2014 Ph.D. Milk-borne bioactive factors: Effects on neonatal
porcine reproductive tissues and uterine function
in adults (started in my lab 9/09)
(Former Teaching Instructor, Rutgers U)
Joseph Chen 2005-2011 Ph.D. Regulation of porcine uterine programming: Effects
of neonatal estrogen and relaxin exposure
(Siemens Healthcare Diagnostics)
Amy Frankshun 2005-2011 Ph.D. The lactocrine role of relaxin in the developing
porcine cervix
(Food and Drug Administration, Rockville, MD)
Emily Lamprecht 2004-2010 Ph.D. Inflammatory responses of horses to intense
exercise and effects of nutritional supplementation
(Cargill Animal Nutrition)
Wenbo Yan 1999-2005 Ph.D. Relaxin action in the reproductive tract: Interaction
with estrogen signaling pathways
(Biology Dept, Nyack College, NY)
Karen Santora 2002-2005 M.S. Effects of relaxin on arthritis and inflammation
(Merck and Company)
Jennifer Neumann 1999-2002 M.S. Production and characterization of recombinant
equine relaxin
(Physician in North Carolina)
27
Graduate students – Primary advisor (con’t):
Student Yrs Deg Project/Thesis Title
Judy Lenhart 1992-1999 Ph.D. Role of relaxin in the control of reproductive tissue
growth. Awards: First Prize, 1996 Cook College
Graduate Research Poster Competition; 1997 GSNB
Teaching Award; (Celgene Corporation)
Kathleen Ohleth 1992-1997 Ph.D. Relaxin: Control of secretion and effects on the
insulin-like growth factor system
(Precise Publications, CEO)
Zhang Qi, M.D. 1989-1994 Ph.D. Role of relaxin in porcine follicular development
and ovulation
(MD, Pathologist)
Graduate students – Member of the thesis committee:
Student Yrs Deg Graduate Program Major Advisor
Chelsee Holloway in progress Ph.D Endo & Anim Biosci L. Quadro
Ali Yasrebi in progress M.S. Endo & Anim Biosci T. Roepke
Seher Yirtici 2016 M.S. Endo & Anim Biosci M. Uzumcu
Jennifer Yang 2016 Ph.D. Endo & Anim Biosci T. Roepke
Allyson Agostini-Dreyer 2014 Ph.D. Nutritional Sciences W. Cohick
Alison Golinski 2013 Ph.D. Endo & Anim Biosci H. John-Alder
Jushen Cheng 2011 M.S. Endo & Anim Biosci W. Cohick
Kristy Longpre 2011 Ph.D. Endo & Anim Biosci L. Katz
Norell Hadzimichalis 2008 Ph.D. Cell & Neurobiology G. Merrill
Brian Leibowitz 2008 Ph.D. Endo & Anim Biosci W. Cohick
AnneMarie Armenti 2007 M.S. Animal Sciences M. Uzumcu
Alvaro Arjona 2006 Ph.D. Animal Sciences D. Sarkar
Jodie Fleming 2006 Ph.D. Animal Sciences W. Cohick
Jill Lindia 2004 M.S. Animal Sciences L. Katz
Meagan Shearer 2003 M.S. Animal Sciences L. Katz
Kim McMunn 2001 M.S. Animal Sciences L. Katz
Bojing Wang 2001 M.S. Animal Sciences W. Cohick
Daniela Maina 1999 Ph.D. Animal Sciences L. Katz
Heather Billings 1998 Ph.D. Animal Sciences L. Katz
Steve Leili 1997 Ph.D. Animal Sciences C. Scanes
Michelle Lane 1996 Ph.D. Animal Sciences B. Jesse
Luquan Wang 1996 Ph.D. Animal Sciences B. Jesse
Gretchen Ritacco 1996 M.S. Animal Sciences P. Schoknecht
Wei-Lun Hung 1995 M.S. Animal Sciences J.P. Advis
Gloria Regisford 1994 Ph.D. Animal Sciences L. Katz
28
Graduate students – External examiner for Ph.D. defense:
Student Yr Institution Thesis Title
Lifu Song 1998 University of Guelph Effects of equine relaxin on the activity of
Guelph, Ontario equine ovarian stromal cells in vitro
J Willcox 2012 University of Guelph The neuroprotective effects of relaxin-2 and
Guelph, Ontario relaxin 3
Undergraduate students - George H. Cook Honors Program
Mindy Feldman, 1991-1992
Thesis: Localization of cadherins in the developing pig follicle
Brian Karolewski, 1992-1993
Thesis: Temporal expression of clusterin gene and protein in the developing ovary
Kuntal Joshi, 1993-1994
Thesis: Cadherin function in the ovarian follicle
Anthony Valentine, 1994-1995
Thesis: Cell adhesion molecules in the porcine ovary: Epithelial cadherin expression
during development.
*First Prize - 1995 Cook College Undergraduate Research Poster Competition
Daniel Baum, 1995-1996
Thesis: Regulation of E-cadherin expression in ovarian cells.
*First Prize - 1996 Cook College Undergraduate Research Poster Competition.
Kathryn McGonigle, 1997-98 Rutgers University Undergraduate Fellow
Thesis: Ovarian Growth: Effects of relaxin and estrogen on connective tissue proteases.
1997 Summer NJ Commission on Cancer Research Fellow
Amy Mallin, 1998-99 Merck/Rutgers Undergraduate Research Fellow
Thesis: Role of E-cadherin in ovarian cell adhesion, apoptosis and cell communication.
Stephanie Dondzil, 1998-99
Thesis: Hormonal control of connective tissue protease activity in ovarian cancer cells.
1999 Summer NJ Commission on Cancer Research Fellow
Kelli French, 1999-2000 Rutgers Undergraduate Research Fellow
Thesis: Characterization of VEGF in porcine reproductive tissues
Stefanie Malkiewicz, 2000-2001 Rutgers Undergraduate Research Fellow
Thesis: Mechanism of growth factor action in an ovarian cancer cell line
2000 Summer NJ Commission on Cancer Research Fellow
29
Undergraduate students - George H. Cook Honors Program (con’t)
Tamiko Yamamoto, 2004-2005 J & J/Rutgers Undergraduate Research Fellow
Thesis: Cross talk between relaxin and estrogen receptor in uterine tissue remodeling
Megan Dilts, 2007-2008 Aresty Undergraduate Research Scholar
Thesis: The role of relaxin on connective tissue remodeling and apoptosis in the neonatal porcine
heart and cervix.
Michael Strug, 2008-2009 Aresty Undergraduate Research Scholar
Thesis: Role of estrogen and relaxin receptors on mouse interpubic ligament sensitivity to relaxin.
Nathalie Sanchez, 2009-2010 Aresty Undergraduate Research Scholar
Thesis: Effects of milk-borne factors on neonatal porcine cardiac development
*First prize – 2009 SEBS Undergraduate Research Poster Competition
Lauren Barron, 2010-2011 Aresty Undergraduate Research Scholar
Thesis: Gut closure in neonatal pigs: Role of colostrum
*First prize – 2011 SEBS Undergraduate Research Poster Competition
Kristene Welch, 2010-2011 Aresty Undergraduate Research Scholar
Thesis: Uterine developmental programming and the impact of lactocrine signaling
*First prize – 2010 SEBS Undergraduate Research Poster Competition
Monica Boulos, 2012-2013 GH Cook Honors Scholar
Thesis: Effects of nursing on porcine cervical development
Nikesh Patel, 2014-2015 GH Cook Honors Scholar
Thesis: Neonatal porcine hepatic cholesterol and triglycerides: Effects of Aminogut
Jessica Lovich, 2014-2015 GH Cook Honors Scholar
Thesis: Effects of duration of nursing from birth on neonatal uterine gene expression
Mary Nasr, 2015-2016 GH Cook Honors Scholar
Thesis: Effects of age and nursing on neonatal porcine small intestine development
Undergraduate Students – Independent Research
Helen Uczkowski, 2011 Douglass STEM Summer Research Experience
Jerika Boulware, 2012 and 2013 Rodkin Science Scholar in support of summer research
Jennifer Wang, 2016-2017 Aresty Program Research Assistant
Project title: Long term effects of nursing from birth on uterine protein during pregnancy in the pig
Summer Internship for Biotechnology High School Students – sponsored Jo Belluardo and
Anya Stoupine during Summer 2008 for a 4 week internship in my laboratory.
30
Cooperative Education Advisor for more than 25 undergraduates since 1988
Academic Advisor for undergraduates majors in Animal Sciences, Biology and
Biotechnology ~ 30 students annually
Independent Research in Animal Sciences (Problems in Animal Sciences; 11:067:494-495)
1989-present; Two students per year
Douglas Project SUPER advisor
1999; Heather Jensen
SERVICE
Professional Service
2017 USDA Grant Review Panel – Animal Reproduction, Member
2009 USDA Grant Review Panel – Animal Reproduction, Member
2008 USDA Grant Review Panel - Animal Reproduction, Member
2007-2008 Society for the Study of Reproduction (SSR), Nominating Committee
Member
2007-2008 SSR, Awards Committee, Member
2000-2001 SSR, Future Meetings Committee, Member
2000 USDA Review Panel – Animal Reproductive Efficiency, Member
1993-1994 SSR, Membership Committee, 1995/96 Chair
1993 NIH-Biochemical Endocrinology Study Section, ad hoc member
1992 NIH Special Study Section - Small Business Innovation Research, ad hoc
member
Rutgers University Activities
2017-2020 Graduate School New Brunswick, Executive Council, Member
2015-2016 TA-GA Professional Development Fund Committee, Member
2008-2011 Busch Biomedical Research Program, Grant reviewer
2007 -pres Graduate School New Brunswick, Biological Sciences Area Committee
2004-2006 Graduate School New Brunswick, Committee of Review
1999-pres University Biosafety Committee, Member
1997-1998 Faculty Panel - Detenurement/dismissal FAS faculty
1996-1999 University Senate, Member
School of Environmental and Biological Sciences Activities
2017-pres SEBS/NJAES Advisory Council, Member
2015-2016 Search Committee for faculty hires in the NJ Institute for Food, Nutrition
and Health, Member
2015 Search Committee for Dept of Ecology, Evolution and Natural Resources,
Assistant Extension Specialist, Chair
31
School of Environmental and Biological Sciences Activities (con’t)
2010 Search Committee for Associate Director of the NJ Institute for Food,
Nutrition and Health, Member
2007 Biochemistry Task Force Committee, Member
2006 Agricultural Experiment Station Budget Committee, Member
2005-2006 College Appointments and Promotions Committee, Co-chair
2003-2005 College Appointments and Promotions Committee, Member
2003-2007 College Faculty Financial Aid Committee
2003 College Grievance Committee, Chair
2002-2008 Special Projects & Tuition Differential Advisory Committee
2000-2001 Cook College Organizational Structural Leadership Strategy Team,
Co-chair
1999-2000 Junior/Senior Colloquium Committee, Member
1994-1998 College Planning Committee, Member
1993-1999 Curriculum and Educational Policy Committee, Member
1992-1993 College Affirmative Action Committee, Chair
1990-2006 G.H. Cook Honors Program Committee, Member
1991 Rutgers Guidance Counselor Program, invited speaker
1991-1993 College Library Representative
Animal Science Department/Biotech Center Activities
2009- pres Pioneers In Endocrinology, organizing committee, Member
2008, 2009 Peer Evaluation Committee (PEC) for Biotech Center, Member
2007, 2016 PEC Committee for Animal Sciences, Chair
2017 PEC Committee for Animal Sciences, Chair
2005 Committee to review Candidate for promotion and tenure, Chair
2002 Committee to review Candidate for promotion to Professor I, Member
1999-2001 Animal Science Chair Advisory Panel, Member
1995-1999 Associate Chair of the Department of Animal Sciences
1993-1995 Departmental Safety Representative
Departmental Committees:
2002-pres Faculty Mentoring Committee for Dr. Mehmet Uzumcu, Chair
1999-pres Faculty Mentoring Committee for Dr. Wendie Cohick, Chair
1996 Evaluating & Rewarding Excellence in Teaching, Chair
1993-1998 Johnson & Johnson Seminar in Reproduction Committee, Chair
Faculty Search Committees:
2015-2016 Endocrine-Epigenetics faculty search, Chair
2008-2009 Endocrine Cluster hire, Ad hoc member
2002-2003 Endocrinology faculty hire, Member
2000-2001 Transgenic faculty hire, Member
2000-2001 Genomics faculty hire, Member
1996-1997 Animal Biotechnologist hire, Chair
1994-1995 Instructor in Reproduction, Chair
1993-1994 Nutrition/genetics faculty hire, Member
32
Graduate Program in Endocrinology and Animal Biosciences
(formerly called Animal Sciences, until 2007)
2014- pres Graduate Program Director
2015, 2017 SEBS Excellence Fellowship Committee, Member
2007-2009 Admissions Committee, Chair
1999-pres TA/GA Appointments Committee, Chair
1995-2009 Academic Standards Committee, Member
1992-1995 Academic Standards Committee, Chair
1990-1992 Admissions Committee, Member
Other Outreach:
Bagnell CA. Sp 2016. Got Milk? Explorations GH Cook Campus Magazine, p.10.
The News Kids, Summer 2015
Television interview by elementary school student journalists in The News Kids program in
Princeton, NJ. Met with students and discussed research on the importance of mother’s milk in
programming development conducted on the Cook Campus farm and in the laboratory.
cv\bagnell 12-8-2017