WHAT
WHY
WHEN
WHERE
HbA1C
Name as a Rose, Smell as a sweet
Hemoglobin (Hb) - Divided into Glycated & Non Glycated Fraction.
H
Hb Hb Hb
HbA1
HbA1a HbA1b HbA1c
HbA0
Normal Adult HbFetal Hb
Glycated
A1a & A1b concentration very low
Main glycohemoglobin used since > 20 years for glycemic control with HPLC
Various Fractions of Glyco Hb
• Glycosylated Hb ( Total GHb)
• HbA1a• HbA1b• Hb LA 1c• Hb A1c – the most accurate indicator
for Glycemic Control
Hemoglobin A1c
Clinical Interpretation of HbA1c Values
HbA1c Value
Interpretation
4 - 6% Normal Value / Non Diabetic
6.1 – 7 % Well Controlled
7.1 – 8 % Unsatisfactory Control
> 8 % Poor Control & Needs Treatment
12.0
11.0
10.0
9.0
8.0
7.0
6.0
5.0
4.0
Clinical Value of “A1c”
• HbA1c - Index of Long term Glucose Control.
Test Results Not Affected By:
•Time of the Day•Meal Intake•Exercise•Just Administered Diabetes Drugs•Emotional Stress.
Monitor HbA1c every 3 months in Type 2 Diabetes
Advantages of HbA1c
• Convenience for the patient.
• Ease – Sample collection – A1c testing.
• A report card for blood sugar values
SOLUTIONS: QUALITY“The Complete A1c Solution”
• Excellent HPLC Precision.
• Interference Recognition.
• Clinical Study method of Choice.
• Superior Quality.
How to reduce “A1c”
• Consistent healthy eating.
• Exercising.
• Consistent testing with
“HITECH Diagnostics”.