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Encapsulation Technologies
Leading the wayWhat is Microencapsulation?Lambson Microencapsulation Technologies
• Size: typically 1µm- 1mm
• Active ingredients are entrapped in a shell or matrix
• This renders them temporarily inactive
• Release of the active is “triggered” by a stimulus
Leading the wayWhy Encapsulate?
Isolate, Protect and Stabilise
Controlled Release
Appearance
Leading the wayIsolate, Protect and Stabilise
• Prevents degradation
• Flavour and odour masking
• Separates reactive components
• Manipulation of encapsulate (Oil & water)
• “Plug and play” add to formulation without changing it
• Flavour /Fragrance burst or slow over time release
Leading the wayControlled Release
Microcapsule
Active
Shear
pH
Temperature
Other
Leading the wayAppearance
Visual cues
Aesthetic appeal
Colour changes
Premier branding
Leading the way
Personal & Home Care
Consumer Markets
Food, Beverages & Nutrition
• Shampoo and Shower gels
• Cosmetic Creams
• Hand Sanitisers
• Deodorants
• Toothpaste
• Detergent & Fabric conditioner
• Targeted release
• Self-healing actives
Pharma & Medicine
• Vitamins, minerals, amino acids & unsaturated fatty acids
• Animal & Plant extracts, Flavours & Fragrances
Leading the wayIndustrial Markets
Construction & coatings Agriculture & Environment
• Pesticides & repellents
• Fertilisers
• Paints, antimicrobials & protection coatings
• Self-healing actives
• Phase changing materials
• Breakage markers
• Inkjet pigment
• Thermochromic dyes Invo-Caps containing Concrete healing active[1]
[1] A Kanellopoulos et al 2017 Smart Mater. Struct. 26 04502
Capsule wall
Encapsulated healing
active
Crack Healed concrete
Illustration of self-healing concrete
Leading the waySelecting the right technology
Consider:
• Core Material• Physical state, size, hydrophobicity• Concentration of active
• Wall material• Market: Consumer or industrial• Application: Isolate, protect, stabilise• Regulatory: grade, FDA, etc.• Release mechanism
• Process• Stability of core material• Particle size and distribution• feasibility
SEM image of Vida-Caps
Light Micrograph of Vida-Caps
Leading the wayInvo-CapCore/Shell Matrix
TechnologyComplex
CoacervationSpray Chilling
Material encapsulatedOils, some aqueous
activesAqueous, oils
Encapsulation material
Gelatine + Gum Arabic Lipids/ waxes, gelatine
% loading of active 90% 40%
Trigger mechanism Pressure, DigestionPressure,
Temperature,Digestion
Particle size 5-1500µm 10-1000µm
Biodegradability
Vegan
Leading the wayInvo-CapCore/Shell Matrix
TechnologyComplex
CoacervationIn situ polymerisation Spray Chilling
Hydrogel matrix beads
Material encapsulatedOils, some aqueous
activesOils, some aqueous
activesAqueous, oils
Large water soluble molecules, oils
Encapsulation material
Gelatine + Gum ArabicMelamine
Formaldehyde, Urea Formaldehyde
Lipids/ waxes, gelatine Alginate, agar
% loading of active 90% 90% 40% 15%
Trigger mechanism Pressure, Digestion PressurePressure,
Temperature,Digestion
Pressure, Diffusionequilibrium
Particle size 5-1500µm 0.1-300µm 10-1000µm 200-4000µm
Biodegradability
Vegan
Leading the wayVida-Caps
TechnologyComplex Coacervation
GelatineComplex Coacervation
Gelatine – free (Vida-Caps)
Material encapsulated
Oils, some aqueous actives Oils, some aqueous actives
Encapsulation material
Gelatine + Gum Arabic Chitosan + Gum Arabic
% loading of active 90% 90%
Trigger mechanism Pressure, Digestion Pressure
Particle size5-1500µm 20-1500µm
Hydro-alcoholicstability
Vegan
Leading the way
20– 1500µmHydro-
alcoholic Stability
Why Choose Vida-Caps?
Encapsulates hydrophobic
materials
High Loading (90%)
Bio-degradable
Vegan
Plastic Free
Pressure release
Bespoke Design
Leading the wayConclusion
Lambson are proud to offer a wide range of encapsulation products, customised to suit your requirements, and created to help take your formulations and developments to the next level.
Leading the way
With offices and facilities in England, Europe, China, Japan and America we offer a truly Global Supply Network.
Thank you for your attentionAny Questions?