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Epidemiology 7010
Epidemiology 7010Class 1 Part 2
Fall 2011
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Todays plan
History and discussion
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Hippocrates Jenner Graunt Snow Hi!
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For if one knows all these things well, or at least the
greater part of them, he cannot miss knowing, when he
comes into a strange city, either the diseases peculiar tothe place, or the particular nature of common diseases,
so that he will not be in doubt as to the treatment of
the diseases, or commit mistakes, as is likely to be the
case provided one had not previously considered thesematters. And in particular, as the season and the year
advances, he can tell what epidemic diseases will attack
the city, either in summer or in winter, and what each
individual will be in danger of experiencing from the
change of regimen.
--Hippocrates. On Airs, Waters, and Places. 400 B.C.E.
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Edward Jenner 1796
Jenner was a surgeon, but more importantly,
he was a good observer.
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dawgsports.com
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6Cowpox
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7Sarah Nelmes handWednesday, August 17, 2011
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http://blog.ozkizil.com/
Blossom
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A popular saying among doctors
during the enlightenment was,
Dont think, try.
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From kealyj's photostream,
downloaded from flickr, 2010
Jenners
Temple of
Vaccinia
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John Snow
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"The experiment, too, was on the grandest scale.
No fewer than three hundred thousand people of
both sexes, of every age and occupation, and of
every rank and station, from gentlefolks down to
the very poor, were divided into two groups
without their choice, and, in most cases, without
their knowledge; one group being supplied with
water containing the sewage of London, and,
amongst it, whatever might have come from the
cholera patients, the other group having water
quite free from such impurity." - Snow, 1855,p. 75.
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Grand Experiment
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Natural Experiment
Definition: The epidemiologist does not
manipulate a risk factor but rather observes the
changes in an outcome as the result of a
naturally occurring situation.
Q: What are some characteristics of a good
experiment?