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LOI Applicant Town Hall Webinar
Washington, DC
February 11, 2015 at 2:00 pm ET
Improving Methods for Conducting
Patient-Centered Outcomes
Research
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Introductions
Improving Methods Requirements
Administrative Requirements
Resources
Submitting Questions:
Submit questions via the chat function in Meeting Bridge.
Ask a question via phone (an operator will standby to take your questions).
Agenda
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PCORI CER Methods Program and Contracts
Staff
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Rachael Fleurence, PhDProgram Director,
Methods and Infrastructure
Jason Gerson, PhDAssociate Director,
Methods
Jason Rotter, MHSProgram Associate,
Methods
Kate McQueston, MPHProgram Associate,
Methods
Maryan Zirkle, MD, MS, MA
Program Officer, Methods and Infrastructure
Emily Evans, PhD, MPH
Program Officer, Methods
Kathryn Smith, MPHProgram Assistant,
Methods
Andrea Heckert, PhD, MPH
Program Officer, Methods
Nora McGhee, PhDMerit Review
Officer
Ashton BurtonContracts Specialist,
Contracts
Improving Methods Requirements
PFA Overview: Improving Methods for Conducting
Patient-Centered Outcomes Research
Available Funds and Duration:
• A total of $12million (direct + indirect) for this cycle
• Up to $750,000 in total direct costs per project
• Maximum project period 3 years
Objectives of this PFA:Research findings that can be trusted
should be generated using valid, rigorous,
patient-centered research methods.
PCORI seeks to fund projects to address
gaps in methodological research relevant
to conducting PCOR.
Improving existing methods to benefit all
stakeholders, including researchers
planning investigations, policy makers
weighing the value of healthcare
interventions, and patients, clinicians, and
caregivers facing healthcare decisions.
Revisions for Spring 2015 Funding Cycle
Decrease of award size from $1,000,000 to $750,000 in total direct costs
Research related to human subjects protections and novel interventions for recruitment
and retention are now designated as Special Topics of Interest
Revised Special Topic of Interest focusing on methods for network-based data in research
The current PFA does not include a special emphasis on PROMIS related projects. We
will still consider projects that include PROMIS measures, provided they align with the S15
PRO/PCO priorities
No support for methods related to research prioritization and systematic reviews
Research Areas of Interest
Development of methods for patient and other stakeholder engagement in research
Development and refinement of general analytic methods
Development and refinement of design-specific analytic methods
Research related to patient-centered outcomes (PCOs) and
patient-reported outcomes (PROs)
Research on usefulness of patient-reported data in clinical care
Research on PRO score interpretability, with a focus on clinical
meaningfulness
Research on the collection of PRO data for multiple purposes
Research on integrating PROs into clinical practice
Research on the use of PROs in registries
Special Topics of Interest
Research on issues related to human subjects protections
Research on novel methods, interventions, or strategies for
increasing recruitment and retention of participants
Development of methods to support data research networks
Methods to improve distributed analyses in data research networks
Methods to obtain longitudinal and complete data in data research
networks
Patient and Stakeholder Engagement Plan
Description of the plan for engaging patients, caregivers,
and/or other stakeholders over the course of the project
Justification for choice of patients, caregivers, and/or other
stakeholders
Delineation of their roles and expected contributions
Consider engaging other stakeholders in the
methodological process and dissemination and
implementation plans
Examples: data architects, clinicians, domain experts, health
services researchers with different expertise than members of the
research team, policy makers, etc.
Administrative Requirements
Eligibility to Submit a Proposal
Any private sector (non-profit or for-profit) research
organization
Any public sector research organization (university or
college hospital or healthcare system, laboratory or
manufacturer, unit of local, state, or federal government)
Non-domestic components of organizations based in the
US and foreign organizations may apply, as long as there is
demonstrable benefit to the US healthcare system and US
efforts in the area of patient-centered research can be
clearly shown.
Individuals are not permitted to apply.
Budget and Period Limitations
Funds & Budget
Total Direct costs up to $750,000 over the life of the project
Indirect costs: up to 40%
Institutional base salary up to $200,000
Period of Performance
Maximum of 3 years
Letter of Intent (LOI)
This is a competitive LOI process:
Only those LOIs deemed most responsive to this PFA will be invited to submit a
full application.
All applicants will be notified of their status by March 23, 2015 by 5:00pm ET.
Download the LOI Template from the Funding Center to begin your LOI.
LOIs cannot exceed 3 pages and margins cannot be altered .
Adhere to the formatting and template requirements in the Application
Guidelines.
You must upload your LOI as a PDF in PCORI Online.
Please refer to the PFA, Application Guidelines, and Applicant Resources in the
Funding Center here http://www.pcori.org/assets/2014/08/PCORI-PFA-2014-Fall-
Methods-Application-Guidelines.pdf
Submission & Key Dates
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What When
LOI-Applicant Town Hall February 11, 2015 at 2:00 pm ET
LOI due in PCORI Online March 6, 2015 by 5:00pm ET
Applicants notified as to
whether they have been
selected to submit a full
application
March 23, 2015 by 5:00pm ET
Application Deadline (by
invitation only)May 5, 2015 by 5:00pm ET
Merit Review Dates August 6-7, 2015
Awards Announced September 30, 2015
Earliest Start Date November 2015
Using the PCORI Online System
Apply through PCORI Online (https://pcori.fluxx.io)
Access the website using Chrome or Safari browsers only
Create a new request and begin the LOI
Designate the LOI with the following individuals:
• PI, PI Designee, AO, and Financial Officer
Enter information into all required fields in the system
Upload the LOI in the system
Save information by clicking the ‘Save and Review’ button on the save and review page and on the side navigation pane
Where can I find help?
Visit pcori.org/apply Application Guidelines FAQs PCORI Online User Manuals Sample Engagement Plans
Schedule a Call with a Program Officer Submit a request at pcori.org/programmatic-inquiry Call 202-627-1884 ( programmatic inquiries) Submit a request at pcori.org/about-us/contact-us
Contact our Helpdesk E-mail [email protected] Call 202-627-1885 ( administrative and
technical inquiries)
Questions
Submitting Questions:
Submit questions via the chat function in Meeting Bridge.
Ask a question via phone (press 7 on your phone).
Please use this time to ask any programmatic and administrativequestions you may have about the PFA or LOI submission process.
If we are unable to address your question during this time, e-mail the help desk at [email protected].