VIROTECH – An Overview
2016
2015
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2012
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2009
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1997
1994
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1992
1988
1986Development of the Virotech system with standardized testing for all ELISA test kits in our portfolio
Beginning of distributing products of Alexon Trend, USA (later Remel, Oxoid and now ThermoFisher Scientific)
Start of distribution of MRL Diagnostics, USA products (today: Focus Diagnostics lnc.)
lntroduction of the first tests for CSF diagnostics - a product area that will be expanded in the following years
Expansion of the product portfolio with Westernblots by Biosens. Set-up and development of the new product line in order to become system diagnostics
Beginning of distribution of Meridian Bioscience, lnc. products
Entering contract manufacturing
Expansion of the distribution of Seramun Diagnostics GmbH‘s stool tests. In addition to that, infection diagnostics of Labsystems Diagnostics complements our portfolio
Expansion of the LINE product line - introduction of the Borrelia Europe LINE, Borrelia Europe LINE+ TpN17, Borrelia in vivo LINE to the European market
Entrance into PCR diagnostics. Beginning of the distribution of EuroClone Diagnostics s.r.l. products
lntroduction of the Pandemic New Influenza A ELISA and the Bordetella pertussis LINE with the innovative CatACT band
lntroduction of the Mycoplasma LINE - the only available LINE on the market until today
We expand our PCR test portfolio in the area of human genetics with the products of Asuragen, lnc.
Enigma Diagnostics Ltd. and Labsystems Diagnostics OY com-plement our product portfolio in the area of PCR diagnostics
Cooperation with the company Kapelan Bio-lmaging GmbH – the Lablmage® LA is available for evaluating our LINE lmmunoassays
Foundation of Virotech Systemdiagnostika GmbH
Establishment of our own antigen production site
Virotech becomes part of the Genzyme Diagnostics family which belongs to the biotechnology company Genzyme – we become Genzyme Virotech GmbH
Genzyme Diagnostics becomes part of Sekisui Medical in Japan and chan-ges its name to Sekisui Diagnostics. We become Sekisui Virotech GmbH
Since December 1st, 2016 VIROTECH Diagnostics GmbHAnniversary year
VIROTECH System Diagnostics ELISA .................................................................................6INFECTIOUSE DISEASE SEROLOGY
Human Diagnostic ELISA .................................................................................................................................... 6
Veterinary Diagnostic ELISA ............................................................................................................................... 9
Preabsorption of Rheumatoid Factors ...........................................................................................................9
Supplementary Material ELISA .......................................................................................................................10
Validation of ELISA Processors .......................................................................................................................10
Evaluation Software ELISA ...............................................................................................................................10
VIROTECH System Diagnostics LINE Immuno Assay ......................................................................................................................11INFECTIOUS DISEASE SEROLOGY
Human Diagnostic LINE ....................................................................................................................................11
Veterinary Diagnostic LINE ..............................................................................................................................13
Supplementary Material LINE .........................................................................................................................14
Interpretation Software LINE (human) - LabImage® LA ............................................................................14
Seramun Diagnostica ...................................................................................................................15INFECTIOUS DISEASE STOOL DIAGNOSTICS
Antigen Detection Tests – ELISA (sample material: stool samples / culture material) ......................15
Serazym® stool test controls as external controls for the Serazym® stool ELISAs ..............................16
Autoimmune Diagnostics – Line Immuno Assay ........................................................................................16
Content
Product Finder AAdenovirus
AB-ELISA / VIROTECH ............................... 6AG-ELISA / Seramun ......................... 15,16
AstrovirusAG-ELISA / Seramun ......................... 15,16
AutoimmunAB-Line / Seramun ................................. 16
BBordetella
AB-ELISA / VIROTECH ................................ 6Line / VIROTECH ...................................... 11
BorreliaAB-ELISA / VIROTECH ............................ 6,7CSF-ELISA / VIROTECH .......................... 6,7Line / VIROTECH ................................ 11,12CSF-Line / VIROTECH ....................... 11,12Veterinary ELISA / VIROTECH ................. 9Veterinary LINE / VIROTECH ................. 13
BrucellaAB-ELISA / VIROTECH ................................ 7
CCampylobacter
AG-ELISA / Seramun ......................... 15,16
Candida albicansAB-ELISA / VIROTECH ............................... 7
Clostridium difficile (Toxin/GDH)AG-ELISA / Seramun ......................... 15,16
CryptosporidiumAG-ELISA / Seramun ......................... 15,16
CytomegalievirusAB-ELISA / VIROTECH ................................ 7CSF-ELISA / VIROTECH .............................. 7
DDiphtheria
AB-ELISA / VIROTECH ................................ 7
EEntamoeba histolytica
AG-ELISA / Seramun ......................... 15,16
EnterovirusAB-ELISA / VIROTECH ............................... 7
Epstein Barr VirusAB-ELISA / VIROTECH ............................... 7CSF-ELISA / VIROTECH .............................. 7Line / VIROTECH ...................................... 12
External ControlsStool diagnostics ..................................... 16
FFSME / TBE
AB-ELISA / VIROTECH ............................... 8CSF-ELISA / VIROTECH ............................. 8
GGiardia lamblia
AG-ELISA / Seramun ......................... 15,16
HHelicobacter pylori
AB-ELISA / VIROTECH ............................... 8Line / VIROTECH ...................................... 12AG-ELISA / Seramun ......................... 15,16
Herpes simplex VirusLine / VIROTECH ...................................... 13
Herpes simplex Virus 1AB-ELISA spez. (gG1) / VIROTECH ......... 8CSF-ELISA / VIROTECH ............................. 8
Herpes simplex Virus 2AB-ELISA spez. (gG2) / VIROTECH ......... 8CSF-ELISA / VIROTECH ............................. 8
Herpes simplex Virus ScreenAB-ELISA / VIROTECH ............................... 8CSF-ELISA / VIROTECH ............................. 8
IInfluenza A
AB-ELISA / VIROTECH ............................... 8
Influenza BAB-ELISA / VIROTECH ............................... 8
MMeasles
AB-ELISA / VIROTECH ............................... 8CSF-ELISA / VIROTECH ............................. 8
Mumps AB-ELISA / VIROTECH ............................... 8CSF-ELISA / VIROTECH ............................. 8
Mycoplasma pneumoniaeAB-ELISA / VIROTECH ............................... 8Line / VIROTECH ...................................... 13
NNorovirus
AG-ELISA / Seramun ......................... 15,16
PParainfluenza
AB-ELISA / VIROTECH ............................... 8
Pertussis ToxinAB-ELISA / VIROTECH ................................ 6
PreabsorptionELISA / VIROTECH ..................................... 9
RRespiratory syncytial Virus
AB-ELISA / VIROTECH ............................... 9
RotavirusAG-ELISA / Seramun ......................... 15,16
RubellaCSF-ELISA / VIROTECH ............................. 9
SShiga Toxin
AG-ELISA / Seramun ......................... 15,16
Software VIROTECHSoftware ELISA......................................... 10Software LINE .......................................... 14
TFSME / TBE
AB-ELISA / VIROTECH ............................... 8CSF-ELISA / VIROTECH ............................. 8
TetanusAB-ELISA / VIROTECH ............................... 9
Treponema pallidumLine / VIROTECH ...................................... 13
VValidation Kit
ELISA / VIROTECH ................................... 10
Varizella zoster VirusAB-ELISA / VIROTECH ............................... 9CSF-ELISA / VIROTECH ............................. 9
YYersinia
AB-ELISA / VIROTECH ............................... 9Line / VIROTECH ...................................... 13
AB = Antibody, AG = Antigen
6
VIROTECH System Diagnostics ELISA
VIROTECH System Diagnostics ELISA
VIROTECH ELISA SystemThe VIROTECH ELISA product portfolio offers a wide range of qualitative, semi-quantitative and quantitative serological test systems for the most relevant infectious diseases. They serve as tools in order to diagnose specific IgG, IgM and IgA antibodies in human serum.
Furthermore, the VIROTECH system ensures a high level of flexibility by offering the possibility to apply dilution buffer, washing buffer, TMB, citrate stop solution as well as conjugates for all parameters.
In addition to serology, VIROTECH ELISAs can be used for detecting pathogen-specific antibodies in CSF within the established system. The index determination of antibodies follows the Reiber system. VIROTECH also offers antibody index controls for ensuring quality control of the daily CSF routine diagnostics.
INFECTIOUSE DISEASE SEROLOGYProduct Format Order Number Description
Human Diagnostic ELISA
Adenovirus ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC121.00
EC121.08
Can be processed in one run with all other kits of the respiratory panel.
Bordetella pertussis ELISAIgG / IgA Testkit 96 wells EC115.00 Sensitive Screening due to use of combined
antigens PT and FHA.
Pertussis Toxin ELISAIgA Testkit
IgG Testkit
IgG Quantification-Set
IgM Testkit
96 wells
96 wells
3 x 2 ml
96 wells
EC215A00
EC215G00
EN215Q60
EC215M00
Highly specific and sensitive diagnostics due to use of pure Pertussis Toxin. Quantitative IgG detection in IU/ml (WHO-Std) by using the IgG quantification set.
Borrelia afzelii + VlsE IgG ELISAIgG Testkit
IgG CSF Standards
IgG Antibody-Index-Control
96 wells
4 x 1 ml
4 x 1 ml
EC022G00
EC022L60
EN022L65
Maximum diagnostic sensitivity and good specificity due to an antigen mix of B. afzelii strain PKo, B. garinii strain PBr and B. burgdorferi ZS7 strain ZS7.
Borrelia afzelii + VIsE IgG Europe ELISAIgG Testkit
IgG CSF Standards
IgG Antibody-Index-Control
96 wells
4 x 1 ml
4 x 1 ml
EC024G00
EC022L60
EN022L65
Increased specificity due to a special cut-off adjustment.
7
VIROTECH System Diagnostics ELISA
Product Format Order Number Description
Borrelia afzelii IgM ELISAIgM Testkit
IgM CSF Standards
96 wells
4 x 1 ml
EC022M00
EC022L80
High sensitivity due a strong expressing OspC-B. afzelii-strain Pko.
Borrelia VlsE IgG ELISAIgG Testkit 96 wells EC023G00 High-specific Screening Assay, coated solely
with the in vivo expressed antigen VlsE.
Brucella ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC101.00
EC101.08
Detect B. abortas, B. melitensis and B. suis.
Candida albicans ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC111.00
EC111.08
Adjusted to primarily detect acute infections in IgG.
CMV ELISAIgG / IgM Testkit
IgG CSF Standards
96 wells
4 x 1 ml
EC113.00
EC113L60
Mix of native and recombinant antigens.
Diphtheria ELISAIgG Testkit 96 wells EC129.00 Usable for survey of vaccination status and
vaccination success. Aligned with WHO standards for quantitative detection in IU/ml.
EBV ELISAIgG / IgM Testkit
IgG CSF Standards
IgG Antibody-Index-Control
96 wells
4 x 1 ml
4 x 1 ml
EC102.00
EC102L60
EN102L65
EBV screening ELISA. A diagnostic statement with regard to seronegativity, suspicion to an EBV primary infection or past EBV infection can be made when combining the two antibody classes.
EBV EA-D ELISAIgG Testkit 96 wells EC202.00 “Early Antigen-Diffuse” belongs to the early
antigens, which are synthesised in the viral replication cycle (acute phase of infection).
EBV EBNA1 ELISAIgG Testkit 96 wells EC204.00 In case of a positive EBNA1-IgG und VCA-
IgM result, the "Diagnostic Factor" is used to make a clear distinction between primary and past infection (see VCA IgM ELISA).
EBV VCA IgG ELISAIgG Testkit 96 wells EC205G00 Includes the important high specific markers
for EBV: gp125 and p18.
EBV VCA IgM ELISAIgM Testkit 96 wells EC203M00 In case of a positive EBNA1-IgG und VCA-
IgM result, the "Diagnostic Factor" is used to make a clear distinction between primary and past infection (see EBNA1 ELISA).
Enterovirus ELISAIgA Testkit
IgG Testkit
IgM Testkit
96 wells
96 wells
96 wells
EC116A00
EC116G00
EC116M00
Coxackievirus B5 and Echovirus 14. Screening assay for the detection of heterotypic IgG-, IgA-, IgM-antibodies.
8
VIROTECH System Diagnostics ELISA
Product Format Order Number Description
Helicobacter pylori ELISAIgA Testkit
IgG Testkit
96 wells
96 wells
EC143A00
EC143G00
Sensitive detection of specific IgG- and IgA-antibodies.
HSV 1 (gG1) ELISAIgG / IgM Testkit
IgG CSF Standards
96 wells
4 x 1 ml
EC130.00
EC130L60
High-specific recombinant glycoprotein gG1.
HSV 2 (gG2) ELISAIgG / IgM Testkit
IgG CSF Standards
96 wells
4 x 1 ml
EC131.00
EC131L60
High-specific affinity-purified glycoprotein gG2.
HSV Screen ELISAIgG / IgM Testkit
IgG CSF Standards
IgG Antibody-Index-Control
96 wells
4 x 1 ml
4 x 1 ml
EC108.00
EC108L60
EN108L65
Screening of IgG and IgM of HSV1 and HSV2 in one assay.
Influenza A ELISAIgG / IgM Testkit
IgA Testkit
96 wells
96 wells
EC118.00
EC118A00
With seasonal updated antigens.
Influenza B ELISAIgG / IgM Testkit
IgA Testkit
96 wells
96 wells
EC119.00
EC119A00
With seasonal updated antigens.
Measles ELISAIgG Testkit
IgG CSF Standards
IgG Antibody-Index-Control
IgM Testkit
IgM CSF Standards
96 wells
4 x 1 ml
4 x 1 ml
96 wells
4 x 1 ml
EC105G00
EC105L60
EN105L65
EC105M00
EC105L80
Complete package of serum and CSF diagnostic.
Mumps ELISAIgG / IgM Testkit
IgG CSF Standards
96 wells
4 x 1 ml
EC106.00
EC106L60
Complete package of serum and CSF diagnostic.
Mycoplasma pneumoniae ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC114.00
EC114.08
Cut-off adjustment to detect acute infections in IgG. Specific infants cut-off adjustment.
Mycoplasma pn. polyvalent ELISAIgG, IgA+M Testkit 96 wells EC214.00 Efficient diagnostic due to simultaneous
detection of IgA & IgM antibodies with one polyvalent conjugate. Cut-off adjustment to detect acute infections in IgG. Specific infants cut-off adjustment.
ParaScreen ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC148.00
EC148.08
Detects Parainfluenza 1-3 in one test run.
9
VIROTECH System Diagnostics ELISA
Product Format Order Number Description
RSV ELISAIgG / IgM Testkit
IgA Set
96 wells
3 x 1.3 ml & 1 x 11 ml
EC107.00
EC107.08
Can be processed in one run with all other kits of the respiratory panel.
Rubella Virus CSF ELISAIgG CSF Testkit
IgG CSF Standards
IgG Antibody-Index-Control
96 wells
4 x 1 ml
4 x 1 ml
EC109L00
EC109L60
EN109L65
CSF Diagnostic for the detection of IgG antibody’s.
FSME / TBE ELISAIgG / IgM Testkit
IgG CSF Standard
IgG Antibody-Index-Control
IgM CSF Standards
96 wells
4 x 1 ml
4 x 1 ml
4 x 1 ml
EC117.00
EC117L60
EN117L65
EC117L80
Sensitive detection of an acute or recent infection with Tick-Borne-Encephalitis-Virus (TBE) or for the detection of vaccination antibodies.
Tetanus ELISAIgG Testkit 96 wells EC124.00 Survey of vaccination status and vaccination
success, routinely aligned with WHO stan-dards for quantitative detection in IU/ml.
VZV ELISAIgG / IgM Testkit
IgA Set
IgA CSF Standards
IgG CSF Standards
IgG Antibody-Index-Control
IgM CSF Standards
96 wells
3 x 1.3 ml & 1 x 11 ml
4 x 1 ml
4 x 1 ml
4 x 1 ml
4 x 1 ml
EC110.00
EC110.08
EC110L40
EC110L60
EN110L65
EC110L80
IgG adjusted as recommended by the Robert-Koch-Institute (aligned to the WHO standard: > 100IU/l = seropositive titer).
Yersinia enterocolitica ELISAIgG / IgA Testkit 96 wells EC142.00 Mix of purified native antigens and
recombinant antigens YopD, YopB & YopE.
Veterinary Diagnostic ELISA
Borrelia burgdorferi IgG Veterinary ELISAIgG Testkit dog / horse
IgM Set dog
96 wells
1 x 1.3 ml & 1 x 11 ml
DC122.00
DC122K80
Sensitive IgG antibody screening of dog or horse serum. Additional IgM diagnostics can be performed with the IgM kit for dogs.
Preabsorption of Rheumatoid FactorsRF-SorboTech Vial - 2 ml 161101 Rheumatoid factor absorbent for all IgM
and IgA+M ELISA tests and Pertussis Toxin IgA ELISA.
RF-SorboTech Vial - 10 ml 161102 Rheumatoid factor absorbent for all IgM and IgA+M ELISA tests and Pertussis Toxin IgA ELISA.
RF-SorboTech 80x 2 vials RF - 2 ml & dilution buffer
B/300.00 Rheumatoid factor absorbent for all IgM and IgA+M ELISA tests and Pertussis Toxin IgA ELISA.
10
VIROTECH System Diagnostics ELISA
Product Format Order Number Description
Supplementary Material ELISATetramethylbenzidine – Substrate Solution
11 ml 151101 General ELISA component
PBS-Washing Solution (20x concen-trated)
50 ml 141201 General ELISA component
Citrate-Stopping Solution 6 ml 141101 General ELISA component
PBS-Dilution Buffer (ready to use) 50 ml 141301 General ELISA component
VZV-IgM-Dilution Buffer (ready to use) 50 ml 141401 General ELISA component
IgA Conjugate (anti-human) 11 ml 131301 General ELISA component
IgA Conjugate 2 (anti-human) 11 ml 131601 General ELISA component
IgG Conjugate (anti-human) 11 ml 131101 General ELISA component
IgG Conjugate (anti-dog) 11 ml DC122.31
IgG Conjugate (anti-horse) 11 ml DC122.33
IgM Conjugate (anti-dog) 11 ml DC122.80
IgM Conjugate (anti-human) 11 ml 131201 General ELISA component
IgA + IgM Conjugate (anti-human) 11 ml 131401
12 breakable microtiter strips (antigen-coated)
1 plate ECXXXX01EC116M02DC122.01
Antigen-coated Enterovirus control antigen Borrelia burgdorferi Veterinary
IgA Set 3 x 1.3 ml & 1 x 11 ml ECXXX.08 IgA Controls and IgA Conjugate
IgA Controls 3 x 1.3 ml ENXXXK40 General ELISA component, filling level 3 x 2 ml by Enterovirus
IgG Controls 3 x 1.3 ml ENXXXK60 General ELISA component, filling level 3 x 2 ml by Enterovirus
IgM Controls 3 x 1.3 ml ENXXXK80 General ELISA component, filling level 3 x 2 ml by Enterovirus
IgG Standard Control Set 8 x 2 ml EN129K60 For use with the VIROTECH Diagnostics Diphtheria ELISA
IgG Standard Control Set 8 x 2 ml EN124K60 For use with the VIROTECH Diagnostics Tetanus ELISA
Validation of ELISA ProcessorsValidation Kit, ELISA 96 wells EC250.00 Kit to verify ELISA devices (semi- or fully
automated.
Pipetting Control-Set 2.8 ml
2 x 50 ml PBS-Dilution Buffer
EN250K60 Set to verify the pipetting process of ELISA devices (semi- or fully automated). For use with EC250.00.
Evaluation Software ELISALabCheck CSF Analysis 1x EX-CSF-GB Evaluation software for CSF diagnostics.
LabCheck 1-Point Quantification 1x EX-1-Punkt Evaluation software for 1-Point quantification for the VIROTECH Diagnostics Diphtheria, Pertussis Toxin and Tetanus IgG ELISA.
LabCheck Validation Kit and Pipetting Control-Set
1x EX-250-GB Evaluation software for the VIROTECH Validation Kit and Pipetting Control-Set.
11
VIROTECH System Diagnostics LINE Immuno Assay
VIROTECH System Diagnostics LINE Immuno Assay
VIROTECH LINE SystemVIROTECH LINE Immunoblots serve the qualitative detection of pathogen-specific IgG, IgM and IgA antibodies in human serum. The coated nitrocellulose test strips enable a high degree of flexibility by covering various system components. Microdispension of antigens at defined positions on the nitrocellulose ensures high reproducibility.
In diagnostics of Borrelia, exclusion bands contribute to a safe serology of IgG and IgM. In addition to that, the VIROTECH Borrelia LINE Immunoblots can be used for detecting antibodies in CSF.
Easy reading and interpretation of VIROTECH LINE Immunoblots can be done visually as well as by utilizing a user-friendly evaluation software.
INFECTIOUS DISEASE SEROLOGYProduct Format Order Number Description
Human Diagnostic LINE
B. pertussis + CatACT LINEIgA Line Immunoblot
IgA Line Immunoblot
IgG Line Immunoblot
IgG Line Immunoblot
IgA cut off Control*
IgA positive Control
IgG cut off Control*
IgG positive Control
IgG / IgA negative control
32 strips
96 strips
32 strips
96 strips
0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
WE116A32
WE116A96
WE116G32
WE116G96
WE116C40
WE116P40
WE116C60
WE116P60
WE116N20
New marker CatACT allows differentiation between vaccination and infection. Note towards parapertussis possible.
Controls separately available.
Borrelia LINEIgG Line ImmunoblotIgG Line Immunoblot
IgM Line ImmunoblotIgM Line Immunoblot IgG cut off Control*IgG positive Control
IgM cut off Control*IgM positive ControlIgG / IgM negative Control
32 strips96 strips
32 strips96 strips 0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
WE222G32WE222G96
WE222M32WE222M96
WE222C60WE222P60WE222C80WE222P80WE222N10
Excellent specificity and sensitivity due to the optimised combination of the most important common antigens (OspC, p39, p83/100) with well-known „in-vivo“ antigens. EBV-band as exclusion marker in IgM diagnostics.
Validated for CSF testing.
Controls separately available.
* supplementary LINE material (included in the kit)
12
VIROTECH System Diagnostics LINE Immuno Assay
Product Format Order Number Description
Borrelia in vivo LINE plusIgG Line ImmunoblotIgG Line Immunoblot IgG cut off control*IgG positive controlIgG negative control
32 strips96 strips
0.5 ml
0.5 ml
0.5 ml
WE223G32WE223G96
WE223C60WE223P60WE223N60
Treponema-band (TpN17) as exclusion marker in IgG diagnostics.
Validated for CSF testing.
Controls separately available.
Borrelia Europe LINEIgG Line ImmunoblotIgG Line Immunoblot
IgM Line ImmunoblotIgM Line Immunoblot IgG cut off control*IgG positive controlIgM cut off control*IgM positive controlIgG / IgM negative control
32 strips96 strips
32 strips96 strips 0.5 ml0.5 ml0.5 ml0.5 ml0.5 ml
WE224G32WE224G96
WE224M32WE224M96
WE224C60WE224P60WE224C80WE224P80WE224N10
Optimised combination of high purified lysate antigens (OspC, DbpA-PKo) and recombinant antigens (VlsE, p83, p58, p39, DbpA-Mix). EBV-band as exclusion marker in IgM diagnostics.
Validated for CSF testing.
Controls separately available.
Borrelia Europe plus TpN17 LINEIgG Line ImmunoblotIgG Line Immunoblot
IgG cut off control*IgG positive controlIgG negative control
32 strips96 strips
0.5 ml0.5 ml0.5 ml
WE225G32WE225G96
WE225C60WE225P60WE225N60
Treponema-band (TpN17) as exclusion marker in IgG diagnostics.
Validated for CSF testing.
Controls separately available.
EBV LINEIgG Line ImmunoblotIgG Line Immunoblot
IgM Line ImmunoblotIgM Line Immunoblot IgG cut off control*IgG positive control
IgM cut off control*IgM positive controlIgG / IgM control
32 strips96 strips
32 strips96 strips 0.5 ml0.5 ml0.5 ml0.5 ml0.5 ml
WE102G32WE102G96
WE102M32WE102M96
WE102C60WE102P60WE102C80WE102P80WE102N10
Double-cut-off strategy for EBNA1-inter-pretation. Tool for a clear differentiation between primary and past infection.
Controls separately available.
Helicobacter pylori LINEIgA Line Immunoblot
IgA Line Immunoblot
IgG Line Immunoblot
IgG Line Immunblot
IgA cut off control*
IgA positive control
IgG cut off control*
IgG positive control
IgG / IgA negative control
32 strips
96 strips
32 strips
96 strips
0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
WE243A32
WE243A96
WE243G32
WE243G96
WE243C40
WE243P40
WE243C60
WE243P60
WE243N20
Therapy-relevant differentiation of virulent and non-virulent strains via CagA and VacA.
Controls separately available.
* supplementary LINE material (included in the kit)
13
VIROTECH System Diagnostics LINE Immuno Assay
Product Format Order Number Description
HSV LINEIgG Line Immunoblot
IgG Line Immunoblot
IgG cut off control*
IgG positive control
IgG negative control
16 strips
32 strips
0.5 ml
0.5 ml
0.5 ml
WE130G16
WE130G32
WE130C60
WE130P60
WE130N60
High specific bands for HSV1 (gG1-recombi-nant) and HSV2 (gG2-purified) as well as a native total antigen band (1+2).
Controls separately available.
Mycoplasma pneumoniae LINEIgA Line Immunoblot
IgG Line Immunoblot IgM Line Immunoblot IgA cut off control*
IgA positive control
IgG cut off control*
IgG positive control
IgM cut off control
IgM positive control
IgG / IgA / IgM negative control
16 strips
16 strips 16 strips 0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
WE214A16
WE214G16
WE214M16
WE214C40
WE214P40
WE214C60
WE214P60
WE214C80
WE214P80
WE214N50
The only commercially available LINE, with an ideal combination of established (P1) & new antigens (P200, P400).
Controls separately available.
Treponema pallidum LINEIgG Line Immunoblot
IgG Line Immunoblot
IgM Line Immunoblot
IgM Line Immunoblot IgG cut off control*
IgG positive control
IgM cut off control*
IgM positive control
IgG / IgM negative control
16 strips
32 strips
16 strips
32 strips 0.5 ml
0.5 ml
0.5 ml
0.5 ml
0.5 ml
WE150G16
WE150G32
WE150M16
WE150M32
WE150C60
WE150P60
WE150C80
WE150P80
WE150N10
High sensitivity and specifity by using recombinant proteins.
Controls separately available.
Yersinia enterocolitica LINEIgA Line ImmunoblotIgA Line Immunoblot
IgG Line ImmunoblotIgG Line Immunoblot IgA cut off control*IgA positive controlIgG cut off control*IgG positive controlIgG / IgA negative control
32 strips96 strips
32 strips96 strips 0.5 ml0.5 ml0.5 ml0.5 ml0.5 ml
WE242A32WE242A96
WE242G32WE242G96
WE242C40WE242P40WE242C60WE242P60WE242N20
High sensitivity and specifity by using of recombinant proteins. Prevalence band YopDD in IgG shows contact with the pathogen.
Controls separately available.
Veterinary Diagnostic LINE
Borrelia Veterinary plus OspA LINEIgG Line Immunoblot (dog)
IgG Horse Set
32 strips
32 strips
DE226G32
DE226K62
Specific LINE assay to detect the most important Borrelia genospecies in dog and horse serum. Differentiation between infection and vaccination antibodies is possible for dogs.
* supplementary LINE material (included in the kit)
14
VIROTECH System Diagnostics LINE Immuno Assay
Product Format Order Number Description
Supplementary Material LINEIgA Conjugate (anti-human) 0.7 ml WE400.42 General LIA component 100x concentrated
IgG Conjugate (anti-human) 0.7 ml WE400.62 General LIA component, 100x concentrated
IgG Conjugate (anti-dog) 0.7 ml DE400.61 100x concentrated
IgG Conjugate (anti-horse) 0.7 ml DE400.62 100x concentrated
IgM Conjugate (anti-human) 0.7 ml WE400.82 General LIA component, 100x concentrated
Dilution- / Washbuffer 50 ml WE200.08 General LIA component, 10x concentrated
Substrate solution (BCIP/NBT) 57 ml WE200.02 General LIA component, ready to use
Incubationtray with 30 cavities, black, to be used with the ProfiBlot automates
1 x WE300.30S For processing with ProfiBlot device
Incubationtray with 48 cavities, black, to be used with the ProfiBlot automates
1 x WE300.48S For processing with ProfiBlot device
Incubationtray with 8 cavities 1 x WE300.08 Manual testing
Record Sheet, black 1 x WE300APB
Record Sheet lined 1 x WE301APB
LabImage® LA is a sophisticated software for efficient recognition and interpretation of the VIROTECH Diagnostics LINE Immunoblot. The complete automation of the strip analysis offers a maximum on standardisation, which significantly contributes to increase efficiency in medical diagnostic laboratories. Of course, bidirectional connection to LIS is possible. For a maximum on flexibility we provide the software in combination with different instruments depending on the size and automation of the laboratory (Examples of packages are listed below).
We would be glad to provide you with a tailored system for your laboratory.
Interpretation Software LINE (human) - LabImage® LA
LabImage® LA Package 1This package includes: LabImage® Reader with PC, LabImage® Soft-ware (CD), VIROTECH SetCards (CD), Manuals.
1 Package F/Lab-Image 1 Validated for VIROTECH Diagnostics LINE immunoblots.
LabImage® LA Package 2This package includes: LabImage® Reader without PC, LabImage® Software (CD), VIROTECH SetCards (CD), Manuals, License dongle.
1 Package F/Lab-Image 2 Validated for VIROTECH Diagnostics LINE immunoblots.
LabImage® LA Package 3This package includes: Flatbed Scanner (Plustek), LabImage® Software (CD), VIROTECH SetCards (CD), Manuals, License dongle.
1 Package F/Lab-Image 3 Validated for VIROTECH Diagnostics LINE immunoblots.
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Seramun Diagnostica
Seramun Diagnostica
In 1992, the company Seramun Diagnostica GmbH was founded south of Berlin. Seramun mainly develops and produces products in order to diagnose pathogens with a focus on stool diagnostics. Serazym® Stool ELISA serve as a direct proof of antigens. Due to a consistent sample dilution and standardized test procedures, all Serazym® Stool ELISAs can be processed either automatically or manually. As a special service, Seramun offers „external quality controls“ for stool diagnostics twice a year.
In the realm of autoimmune diagnostics, Seramun Diagnostica GmbH has developed a panel of LINE Immunoassays: the Seraline® products. Evaluation of Seraline® strips can be processed either automatically with the Seraline® scan software or visually.
INFECTIOUS DISEASE STOOL DIAGNOSTICSProduct / Format Order Number Features
Antigen Detection Tests – ELISA (sample material: stool samples / culture material)
Serazym® Campylobacter96 wells2 x 96 wells
HW/E-093HW/E-093-A2
Specific detection of Campylobacter jejuni and Campylobacter coli in stool and culture samples.
Serazym® Clostridium difficile GDH96 wells2 x 96 wells
HW/E-107HW/E-107-A2
Sensitive screening for the detection of Glutamatdehydrogenase of Clostridium difficile.
Serazym® Clostridium difficile Toxin A + B96 wells2 x 96 wells
HW/E-040HW/E-040-A2
Sensitive detection with a biotin/streptavidin conjugate system of Toxin A & B in stool and culture samples.
Serazym® Verotoxin 1 + 296 wells2 x 96 wells
HW/E-030HW/E-030-A2
Sensitive detection with a biotin/streptavidin conjugate system of Verotoxin 1 & 2 (Shiga Toxin 1 & 2) in stool and culture samples.
Serazym® H. pylori 2nd Gen.96 wells HW/E-114-A Sensitive detection of Helicobacter pylori with monoclonal antibodies.
Serazym® Adenovirus96 wells2 x 96 wells
HW/E-017HW/E-017-A2
Detection of the capsid protein hexon, common to all human pathogenic Adenovirus serotypes.
Serazym® Astrovirus96 wells2 x 96 wells
HW/E-045HW/E-045-A2
Detection of Astrovirus specific antigens in a short incubation time of 60-10 min.
Serazym® Norovirus96 wells2 x 96 wells
HW/E-061HW/E-061-A2
Detection of Norovirus capsid proteins of the genogroups GGI and GGII.
Serazym® Rotavirus96 wells2 x 96 wells
HW/E-020HW/E-020-A2
Detection of the major protein VP-6 of group A Rotaviruses.
Serazym® Cryptosporidium parvum96 wells HW/E-039-A Sensitive detection with monoclonal antibodies.
Serazym® Entamoeba histolytica96 wells HW/E-018-A Sensitive detection of Entamoeba histolytica.
Serazym® Giardia96 wells HW/E-106-A Sensitive detection of cyst-wall-protein 1 (CWP-1) despite intermittent
excretion.
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Seramun Diagnostica
Serazym® Stool test controls are tools for external quality controls for ELISA stool diagnostics of infectious pathogens. Two stool test controls are offered as a set with 400µl each per test parameter in a stabilized stool suspension. Shipping of the sets is offered twice a year on previously fixed dates. The dates are announced by VIROTECH Diagnostics GmbH. After the expiration date the qualitative results (positive or negative) will be announced on our website.
Product / Format Order Number Features
Serazym® Stool test controls as external controls for the Serazym® stool ELISAs
Serazym® Stool test control Campylobacter2 x 400µl HW/EK-093 controls with unknown result, twice a year.
Serazym® Stool test control Clostridium difficile GDH2 x 400µl HW/EK-107 controls with unknown result, twice a year.
Serazym® Stool test control C. difficile Toxin A+B2 x 400µl HW/EK-040 controls with unknown result, twice a year.
Serazym® Stool test control Verotoxin 1+22 x 400µl HW/EK-030 controls with unknown result, twice a year.
Serazym® Stool test control H. pylori 2nd Gen.2 x 400µl HW/EK-114 controls with unknown result, twice a year.
Serazym® Stool test control Adenovirus2 x 400µl HW/EK-017 controls with unknown result, twice a year.
Serazym® Stool test control Astrovirus2 x 400µl HW/EK-045 controls with unknown result, twice a year.
Serazym® Stool test control Norovirus2 x 400µl HW/EK-061 controls with unknown result, twice a year.
Serazym® Stool test control Rotavirus2 x 400µl HW/EK-020 controls with unknown result, twice a year.
Serazym® Stool test control Cryptosporidium parvum2 x 400µl HW/EK-039 controls with unknown result, twice a year.
Serazym® Stool test control Entamoeba histolytica2 x 400µl HW/EK-018 controls with unknown result, twice a year.
Serazym® Stool test control Giardia2 x 400µl HW/EK-106 controls with unknown result, twice a year.
Autoimmune Diagnostics – Line Immuno Assay
Seraline® Zöliakie-3 IgG20 strips HW/LIA-001-3G Line Immunoassay for detection of IgG antibodies to Gliadin, Tissue
Transglutaminase (tTG) and Mannan in human serum or plasma.
Seraline® Zöliakie-3 IgA20 strips HW/LIA-001-3A Line Immunoassay for detection of IgA antibodies to Gliadin, Tissue
Transglutaminase (tTG) and Mannan in human serum or plasma.
Seraline® ANA-12 IgG20 strips HW/LIA-002-12G Line Immunoassay for detection of IgG-antibodies in connective tissue
diseases in human serum or plasma.
Seraline® Vaskulitis-3 IgG20 strips HW/LIA-003-3G Line Immunoassay for detection of IgG-antibodies in systemic vasculitis in
human serum or plasma.
Seraline® HepAk-7 IgG20 strips HW/LIA-004-7G Line Immunoassay for detection of IgG-autoantibodies in autoimmune liver
diseases in human serum or plasma.
We supply our products worldwide and have collaborations with more than 30 distributors. We are constantly looking for new distributors to expand our distributor network.
Interested? Please contact us!
VIROTECH – International
Michael Becker
International Sales [email protected]
Dominic Drozd
Order Processing [email protected]
You are already Distributor and need support?
Product Information / Product Management:[email protected]
Product Safety / Support:[email protected]
VIROTECH Diagnostics GmbH
Löwenplatz 565428 Rüsselsheim
Product List VIROTECH Diagnostics GmbH, V1/2017e used pictures oficially purchased at Fotolia, LLC
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CO2 compensated print. Supports the project LifeStraw® drinking water purification, Kenia.