Michelle Multiple Sclerosis Denmark
Introduction to Sanofi and Genzyme
495/MetroWest Partnership's Conference Panel
December 15, 2015
• Who is Sanofi?
• Who is Genzyme
• MetroWest Investment
−Talent
−Real Estate
−Community Relations
Overview
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Sanofi is a global healthcare leader focused on patients’ needs:
• engaged in the research, development, manufacturing and marketing
of therapeutic solutions focused on patients’ needs. Sanofi has core
strengths in diabetes solutions, human vaccines, innovative drugs,
consumer healthcare, emerging markets, animal health and
Genzyme.
• 4th largest pharmaceutical group in the world
• Headquartered in France
Who is Sanofi?
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SANOFI AT A GLANCE
CORPORATE PRESENTATION 2015 4
Our missionWe act with our partner to protect health, enhance life and respond to the hopes and potential healthcare needs of 7 billion people around the word.
3 business segments
Pharma Human vaccines
Animal Health
3 CommitmentsExploring the boundaries of medical innovation for patients
Preventingdisease and supportingpatients
Improving access to healthcare
More than
110,000employees
Present in
100countries
€33.8 millionIn sales 2014
SANOFI AT A GLANCE
OUR3 BUSINESS SEGMENTS
CORPORATE PRESENTATION 2015 5
HUMAN VACCINES
>Pediatric vaccines
> Influenza vaccines
>Booster vaccines for adults and adolescents
>Meningitis vaccines
>Vaccines for travelers and endemic areas
ANIMAL HEALTH
PHARMA PRODUCTS
>Anti-parasitics
>Anti-infectives
>Anti-inflammatories
>Anti-ulceratives
VACCINES
>Foot and mouth disease
>Rabies and pets vaccines Range
>Avian vaccines
PHARMA
>Diabetes
>Cardiovascular disease
>Rare diseases
>Multiple sclerosis
>Oncology
>Consumer Health care
>Generics
Net sales
€27,720 MNet sales
€3,974 MNet sales
€2,076 M
© G. Blonsky/Capa Pictures
Information of December 31st 2013
present in more than
100 countries
more than
110 000employees
112Industrial sites
in 41 countries
R&DA major
biopharmacy player
45% of revenues
generated by biologics
80% of development
projects are biologics
€33.8 million
In sales in 2014
Emerging markets
Diabetes solutions
Vaccines
Consumer Healthcare
Animal Health
Genzyme
Other Innovative Products
GROWTH PLATFORMS
• A pioneer of the biotechnology movement in the early 1980s, Genzyme
has always been driven by cutting-edge science and a commitment to
treating unmet medical needs.
• Genzyme has pioneered the development and delivery of
transformative therapies for over 30 years. Founded in 1981 in Boston,
Massachusetts, Genzyme evolved from a tiny start-up with just a
handful of employees to one of the world's leading biotech companies.
Acquired by Sanofi in 2011, Genzyme now benefits from the reach and
resources of one of the world’s largest pharmaceutical companies, with
a shared commitment to improving the lives of patients.
• Genzyme has long been known for our expertise in the class of rare
genetic diseases known as lysosomal storage disorders (LSDs). We
have also expanded – through both in-house development and
strategic acquisitions and partnerships – to other disease areas such
as thyroid cancer and multiple sclerosis
• Generated €2,604 million in Sales for 2014, an increase of 24%
Who is Genzyme?
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RareDiseases
• Lysosomal Storage Disorders (LSDs) are the cornerstone of Genzyme's rare disease business
• Leverage our legacy to expand our expertise in additional therapeutics areas
• Innovative partnership with Alnylam focused on RNAi
TREATMENT AREAS
Gaucher disease type 1Pompe disease
MPS I & II diseaseFabry disease
Thyroid cancerHomozygous Familial
Hypercholesterolemia
THEREAPEUTIC AREAS
HematologyNephrology
NeurologyPediatric
EndocrinologyOther
Sol Pompe disease
Eva & Alberto Fabry disease
Multiple Sclerosis
• MS business unit launched with the approval of two new therapies in 2013
• Unique, personalized approach to patient care
• Strong early-stage MS pipeline focused on targeted immunomodulation, neuroprotection, remylenation, and progressive MS
Once-daily oral therapy for relapsing remitting MS
Infusion therapy for relapsing remitting MS – 2 annual treatment courses
ShaniMS
TigerMS
• Sanofi Genzyme is the largest Bio-Pharma employer in
Massachusetts, with a combined 5,000 Sanofi Genzyme employees.
• Genzyme consistently ranks as one of the top charitable companies
in Massachusetts, leading the Bio-Pharma industry.
• Genzyme’s footprint stretches beyond the traditional center of
Kendall Square, with sites in Allston, Framingham, Westborough and
Northborough.
MA Landscape: Genzyme’s Impact
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Sanofi Genzyme MetroWest Facts!
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Located in
19
buildings
2300 full
time
employees
Filled ~370
of the ~540
open
positions
2015
Real estate
capacity to
support an
additional
~1100
employees
Top 3 sources
of talent
finding:
• Internal
• Referral
• Direct
Dedicated
R&D Center
and
Manufacturing
Operations
Genzyme Northborough Operation Center (gNOC)
• Located in Northborough,
Massachusetts
• Nearly 20 Acres of property
with a 20 year lease. Over
200,000 square feet of
warehouse space, fully
equipped to meet the growth
of Genzyme and meeting
Quality standards
• Approximately 200
employees
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gNOC Facts
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Total Size: 254,095 sq ft2 TSA Certified Cargo Screening Areas
24/7 Full-Perimeter Security2 Megawatt Diesel Backup Generator
Materials OperationsWarehouse 134,813 sq ft
CRT 4,350 pallets2-8C 791 pallets-20C 316 pallets
Receiving 9 docksShipping 6 docksOffices 1,202 sq ft
Quality Control Raw MaterialsWarehouse 10,197 sq ft
CRT 480 palletsLab 3,200 sq ftSampling suite 2,000 sq ftOffice 4,326 sq ft
Clinical SuppliesWarehouse 10,160 sq ft
CRT 654 palletsOffices 5,923 sq ft
Labeling & Packaging GroupPackaging Suite 9,194 sq ft2-8C 500 sq ftOffices 5,923 sq ft
• Cerezyme• Fabrazyme• Myozyme / Lumizyme• Clolar• Thyrogen• Aldurazyme• Elaprase• SepraFilm• LeGoo• Hyaluronic Acid (HA)
Materials Support
Genzyme in Westborough
EmployeeVolunteerism
• Moved into One Research Drive from Framingham on November 21, 2014• 500 employees working across multiple functions:
− Genzyme Industrial Operations Global Leadership and support functions− Genzyme Corporate Quality Operations and Global Quality Leadership− Sanofi Information Solutions− Sanofi Human Resources (including Staffing)− Sanofi Regulatory Affairs and Procurement
Community Relations
EmployeeVolunteerism
GoodNeighbors
Health+Access
ScienceEducation
Our Community Relations mission is to have a lasting positive impact where our employees live and work, by building sustainable partnerships through a combination of financial contributions and employee involvement.
Dedicated and Committed Community Relations
Mission in MetroWest!
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In 2014, Genzyme awarded ~$125,000 in
grants/sponsorships to MetroWest Organizations
Genzyme Science
Kids program at Fuller
Middle School
Boys and Girls Club
of MetroWest
Big Brothers Big
Sisters of Central
Mass MetroWest
Community Farms
OutreachFamily Promise
MetroWest
Framingham Public
Library
Habitat for Humanity
of
MetroWest/Worcester
MetroWest Free
Medical Program
Ashland Fire
Department
Association
Thank You!
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