MD/PhD Program “Molecular Medicine“
Hannover Medical School
Report 2003
MD/PhD Program “Molecular Medicine“
Hannover Medical School (MHH)
Responsible persons Univ. Prof. Dr. Reinhold E. Schmidt Chairman MD/PhD Program Carl-Neuberg Str. 1 30625 Hannover Tel: 0511-532-6656 [email protected] MD/PhD commission:
Prof. Dr. E. Ungewickell, Prof. Dr. A. Gossler, Prof. Dr. J. Schmidtke, Prof.’in Dr. B. Schlegelberger, Prof. Dr. C. Klein, Prof. Dr. R. Förster, HD Dr. B. Sodeik, PD Dr. T. Tschernig, Dr. S. Münte, Dr. F. Bahlmann, Dr. C. Nassenstein, Dr. E. Hesse Dr. Susanne Kruse, Marlies Daniel MD/PhD Office
OE 9117 Carl-Neuberg Str. 1 30625 Hannover Tel. 0511-532-6011 [email protected] [email protected] Internet: www.mh-hannover.de/studium/phd
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President of Hannover Medical School
Hannover Medical School is proud to offer the first PhD program in Germany to be accreditated according to European standards. The main issue of this international postgraduate program is to train young German medical doctors as well as students from life sciences and to attract participants from abroad. The Medical School Hannover is making an important effort to get a higher degree of internationalization. Hannover Medical School is the youngest Medical School in Germany, located on the Campus Roderbruch, which is in the eastern part of Hannover. The main scientific topics are transplantation research, research in mucosal immunity, in infectious diseases and in immunity, in cell biology and specially in stem cell research. Most of all scientific activities are organized in a multidisciplinary approach, including preclinical and clinical departments. Many thanks to the organizers, lecturers and supervisors of this program. I hope that the best young scientists from everywhere will be interested in coming to Hannover. Professor Dr. Horst v. der Hardt President of the Hannover Medical School, 03/99-03/04
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Chairman
The MD/PhD program „Molecular Medicine“ was established in autumn 2000. Last year, the first students did successfully graduate with outstanding achievements. Our program has meanwhile become one of the leading MD/PhD programs in Germany due to excellent interdisciplinary cooperation between the Hannover Medical School, the University and the School of Veterinary Medicine Hannover due to the support of the International Promotion Program (IPP) by DAAD and DFG. It is also the first German PhD program which has been accreditated according to European standards (modules ECTS). There is a good ratio between medical students and students from life sciences as well as between German and foreign students. This program attracts great national and international interest. Additionally, the MD/PhD porgram is the basis for the Hannover Biomedical Research School founded in 2003. Many thanks to everyone who has supported this new MD/PhD program, especially to those students who will determine the future excellence of the program.
Reinhold E. Schmidt, MD Professor of Medicine and Immunolgy
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We express our thanks to our sponsors: “Friends of MHH”
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Table of Contents
I. Current Status, Problems and Prospects ________________________ 15
1. Current Status ___________________________________________________________________ 15 2. Common Rules ___________________________________________________________________ 17 3. Cooperation with International Institutes_____________________________________________ 17 4. Measures for Implementation_______________________________________________________ 19
II. Measures and Results _______________________________________ 19
1. Personnel _______________________________________________________________________ 19 1.1. Scientific collaborators and administrative personnel__________________________________________ 19 1.2. Tutors ______________________________________________________________________________ 20
2. Language courses_________________________________________________________________ 20 3. Social Activities __________________________________________________________________ 20 4. Organization of Educational Material________________________________________________ 21 5. Marketing Measures ______________________________________________________________ 21 6. Guest Lectures and additional colloquia ______________________________________________ 22 7. Travel __________________________________________________________________________ 23 8. Visits abroad by the graduate students _______________________________________________ 23
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I. Current Status, Problems and Prospects
1. Current Status
At the moment there are 58 students in the program [23 women und 35 men; 35 international and 23
Germans; 34 medical students (incl. veterinary students) and 24 scientists]. The international students
come from Argentina (1), China (3), Columbia (1), Ethiopia (1), Georgia (1), Hungary (1), India (19),
Indonesia (2), Japan (1), Slovakia (1), Syria (1), the Netherlands (1), Turkey (1) and Ukraine (1). The
students are either financed by the corresponding departments or by scholarships (DAAD;
“Gesellschaft der Freunde der MHH“; Winkra Energie etc.).
Concerning selection of the new students, a 3-step level procedure was introduced in 2002. It consists
of: 1. preselection by the PhD commission, 2. a written test in the individual home countries, 3. an
interview (in 2003 in Hannover and New Delhi and Hyderabad, India). In 2002 an extensive
application form was developed, which as further improved in 2003.
The selection of the applicants is based on qualification only. The accepted candidates are supposed to
choose a department and a research project themselves. This means that there can be bottle-necks
regarding the guarantee of the financing of the students. For this reason scholarships were applied for
with e.g. the EU - Marie Curie Programm.
Students work on a 3-year research project in one of the departments of the MHH or at cooperating
institutes (see list of students). In addition, there is an obligation program of teaching consisting of
seminars and tutorials (see list of lecturers). In the first year basics and methodics of biology and
medicine are taught. During the second academic year, focus lies more on current research projects
(applied aspects). Since 2003, four main foci have been established: Immunology; Infection; Oncology
and Differentiation; Genetics and Cell Biology (see Curriculum, Fig. 2). Besides an extensive English
curriculum, guest seminars, scientific colloquia, discussions with the supervisors and technical
practical courses took place. Most important are the so-called “soft skills“ as well as seminars about
“Ethics“ (Prof. Schmidtke), “Animal Experiments“ (Prof. Hedrich), “Scientific Writing“ (Dr. Kruse),
“Presentation techniques” (Prof. Dierks) etc. The students keep book about all seminars. At the end of
every semester an evaluation of the educational programs and lecturers is performed.
After 18 months, students give an oral intermediate exam in the respective main subject and the
subject of the co-supervisor (presentation and discussion of a research paper). After 3 years the final
exam takes place in form of a public disputation. In 2003, six MD/PhD students (Massoumeh Attaran,
Yasmin Dulkys, Veit Erpenbeck, Gernot Sellge, Julia Skokova, Andreas Tiede) suceessfully finished
the program. 8
The ECTS System was introduced (credit points = cp; see Fig. 1). The program was accreditated
according to European standards by ZEvA on December 9th, 2003.
Figure 1. Study Structure MD/PhD Program “Molecular Medicine“
The current structure of the Curriculum is as follows:
Figure 2. Curriculum 2003/4
3-year PhD project work (125 cp) Annual presentation in department (3x; 10 cp) Journal club (3x; 3 cp) Public annual presentation/project report (3x; 10 cp) Talk/presentation on international congress (2 cp)
Basics (seminar and tutorial; 3 h per week; 8 cp)
Year 1 Year 2 Year 3
Interdisciplinary seminars/courses (60 h; 6 cp) Project-orientated seminars/courses (80 h; 8 cp)
PHD thesis
and Final exam Complex and clinical
systems (seminar and tutorial; 3 h per week; 8 cp)
Intermediate Exam after 18 month
1st year
In parallel: special in-depth seminars for medical students and students from life sciences, respectively
Basics in Molecular Medicine (Focus on Methods); Seminar Tuesday, 2h
Tutorial Thursday, 1h
Tutorial for the respective seminar on Tuesday
Christmas 1st sem. 2nd sem.
2nd year
1. Focus: Immunology
2. Focus: Genetics and Cell Biology
3. Focus: Infection
4. Focus: Differentiation and Oncology
or
or
4th sem. 3rd sem.
}
For all: Seminar Tuesday, 2h and Tutorial Thursday,
In September 2002, a nation-wide network of biomedically orientated PhD programs was established
by the MHH to which 11 different universities currently belong. In 2003, two meetings took place (in
Bonn). Discussions were going on about mutual aims, problems and cooperations. There will be a
further improvement of coordination of the selection procedures (exams and interviews).
2. Common Rules
On 15.12.99, a rule for the MD/PhD program was passed by the senate of Hannover Medical School.
This rule unites a regulations for studies and exams. On 12.02.02, the MD/PhD program received
authorization from the Lower Saxony Ministry for Science and Culture to alternatively award besides
the PhD title for scientists the title Dr. rer. nat. Such changes in the rules and adaption to the program
situation were passed by the senate on 04.06.02. On 11.02.04, the rules were adapted to the
suggestions by the committee of referees for accreditation and were overall updated. The PhD rules
consider all aims of the program.
3. Cooperation with International Institutes
Fortunately within the MHH there is an active exchange, i.e. participation of almost all scientifically
active departments in the MD/PhD program – whether by means of active organizing within the
MD/PhD commission, by supervising the MD/PhD students at the research laboratories or as lecturers
in the numerous educational programs. This goes for the basic scientific as well as for the clinically
orientated departments, for example: Biochemistry, Dermatology, Developmental Biologiy, Genetics,
Hematology, Hepatology and Gastroenterology, Heart and Thoracic Surgery, Immunology,
Microbiology, Nephrology, Neurology, Oncology, Pathology, Physiology, Rheumatology, Tumor
Biology, Visceral and Transplantation Surgery, Cell Biology etc. Therefore intensive cooperation
exists between collaborators (Post-docs etc.) from Graduate Colleges with the MD/PhD program.
Moreover, the “Graduate School” (Hannover Biomedical Research School) was founded in October
2003. There is close cooperation between the graduate and PhD programs of the School of Veterinary
Medicine Hannover, also concerning lecturers and students. Thanks to the scientists of the MHH there
is already intensive cooperation with European and internationally very well-known research institutes
(e.g. also by means of the European Graduate College “Pseudomonas: Pathogenicity and
Biotechnology“). Of course, the PhD students profit from this cooperation, too.
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A constant exchange and participation in education and research exists with the following institutes:
a) national:
• German Research Center for Biotechnology (GBF); Braunschweig
• School of Veterinary Medicine, Hannover
• Fraunhofer Institute for “Toxicology and Experimental Medicine”, Hannover
• Max Planck Institute for “Experimental Endocrinology“, Hannover
• Institute for “Animal Breeding”, Mariensee (FAL)
• Center for Stem Cell Research, Gatersleben
There is intensive cooperation with these national institutes as well as concerning education (lecturers)
and concerning research, i.e. making three year projects available or the function of scientists as co-
supervisors.
b) international (especially with):
• Cincinatti Children’s Hospital, Ohio, USA
With Prof. Dr. J. Köhl close cooperation. Exchange of scientists is planned.
• Scripps Research Institute, La Jolla, USA
Dr. Tanja Heller (student of 1. academic year) is spending two research years in La Jolla with the
Emmy Noether Program (DFG). An intensive scientific exchange results from this.
• Centre for DNA Fingerprinting (CDFD), Hyderabad, India
With Prof. Dr. S. Hasnain there has been intensive contact since 2002 (see guest lecturer and trip to
India). The establishment of a mutual “summer school“ is planned (application at Volkswagen
Foundation) and the exchange of scientists.
• Centenary Institute, Sydney, Australia
Marc H. Dahlke (Student of the 2. academic year) is currently spending one research year in
Sydney.
c.) Economy/Industry (especially with):
IPF PharmaCeuticals GmbH, Hannover
Industry excursions (e.g. Schering AG, Berlin).
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4. Measures for Implementation
The MHH has guaranteed to continue financial support of the MD/PhD program after discontinuation
of the support by the DAAD/DFG (after 5 years). The MD/PhD program will play a key role in all
respects (scientific, organization) in Hannover Biomedical Research School. The establishment of the
Graduate School will be considered in the future budget.
The accreditation (see above) implements the program.
II. Measures and Results
The MD/PhD Program “Molecular Medicine“ started in winter semester 2000/01. Since 01.01.2002
the program is supported by the DAAD/DFG by means of the “International Promotion Program”
(IPP).
1. Personnel
Within the IPP the posts for a scientific coordinator (full time) and funds for assistant students (see
“non scientific care”; 10 hours/week) have been granted.
1.1. Scientific collaborators and administrative personnel
Since 01.05.2002 Dr. Susanne Kruse has been working on the program as scientific coordinator. She
is a graduated biologist and, therefore, most competent for the sector “Molecular Medicine”. She has
various tasks; she is responsible for the total coordination and organization of the MD/PhD program,
e.g.
• Consultation of the PhD students and applicants
• Organization and coordination of the application procedure
• Cooperation with the PhD commission
• Processing of the PhD commission meetings
• Contact to supervisors and lecturers of the Medical School and cooperating institutes
• Public relations (articles, homepage design etc.)
• Marketing (flyers, poster, advertisements etc.)
• Fund raising (incl. sponsors); applications (EU, „Stifterverband“,BMBF etc.)
• Planing of the curriculum
• Organization of workshops/seminars
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• Presentation of the seminar “Scientific Writing“
• Evaluation of seminars and tutorials
• Preparation of exams and coordination
• Organization of the inauguration, non scientific care and social activities
• Contact to DAAD and other PhD programs (esp. MD/PhD Network)
• Organization und application for accreditation
• Administration of the budget
• Instruction of the person in charge (Mrs. Daniel), the German teacher (Mrs. Marotz)
and both assistant students (see below!)
Mrs. Marlies Daniel works at the PhD Office (full time) as person in charge/correspondant. Her
position is financed by the Hannover Medical School.
Mrs. Daniel supports Dr. Kruse with the coordination und organization of the MD/PhD program. She
is responsible for the total correspondence, telephone calls, organization of the application procedure,
taking care of the students (esp. during the training period: organization of accommodation, banks,
insurance etc.), statistics etc.
1.2. Tutors
Rebecca Bieber und Julia Fraedrich have been employed as assistant students for each 5 hours/week
since 01.07.2002. Both tutors especially take care of the MD/PhD students in close cooperation with
the “International Office” (concerning culture, geography, history and institutions) and help at German
authorities.
2. Language courses
Mrs. Petra Marotz has been employed as the German teacher since 01.10.2002 (hourly basis) with a
lectureship. She teaches the foreign PhD students in two courses à 2 hours/week. This concerns a
course for beginners and an advanced course (1 year experience). A total of 15 MD/PhD students
participate in the courses.
3. Social Activities
• On 31.05.03, a tour to Papenburg took place, main organization of the “International office”.
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• On 11.07.03, 20 MD/PhD students visited the company Schering AG in Berlin.
• On 17.07.03, the summer term was closed by a grill party in the courtyard of building I1. Lots of
students, lecturers and supervisors came.
• From 23. – 24.08.03, a trip to the North Sea for all international students was organized by the
DFA (Deutscher Famulanten Austausch).
• The orientation weeks (from October 1st), which were organized for the first time, were supported
by the “WIN” (welcome in Niedersachsen) program of Lower Saxony.
• The opening of term was celebrated on 14.10.03. All students, lecturers, supervisors, the head of
MHH as well as a large number of invited guests came. Invited speaker: Dr. Josef Lange (State
secretary of the Ministery of Research). Musical introduction: Pure Desmond (Hargassner).
• On 07.11.03, the six MD/PhD final exams were celebrated. Invited speaker: Prof. Dr. D.
McConnell (Trinity College, Dublin, Ireland).
• On 21.11.03, 17 MD/PhD students visited the town hall of Hannover, invited by Ingrid Lange
(deputy major).
• On 06.12.03, a bus excursion to Bremen took place together with the “International Office”. We
had a guided tour and a visit to the art museum (Paul Klee exhibition).
• On 18.12.03, an international Christmas party was celebrated with all MD/PhD students, lecturers
and supervisors.
4. Organization of Educational Material
For the seminars/lectures another “Beamer” was bought. The MD/PhD office moved to building I4
(level 1) in November. We have two offices and two seminar rooms now. Another PC and colour laser
printer were bought. All equipment was added to the inventory by the Medical School. Four different
basic textbooks (Immunology; Genetics; Cell Biology; Developmental Biology) were bought and are
available now for all MD/PhD students in our cabin in the library.
5. Marketing Measures
• For marketing uses, flyer and poster were created and printed by the agency HzweiS. These were
distributed on meetings, congresses, within MHH and other universities.
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• A large number of ads were published in Nature, die Zeit, Science, HAZ, MAI Journal, SZ,
Laborjournal etc.). The resonance was enourmous (300 applications).
• Within MHH, poster are put up to inform employees and students of events (info meetings,
ceremonies etc.), printed by the “Forschungswerkstätten”.
• A year book 2002 was printed, supported by sponsors.
• On 15.04.03, an info meeting on the MD/PhD program was organized for scientists and students.
• Because of the accreditation, the MD/PhD program serves as a model and advisor for lots of other
programs.
6. Guest Lectures and additional colloquia
• On 31.01.03, the seminar “Scientific writing” was given by S. Kruse at MHH.
• From 21. – 22.02.03, Prof. Schmidtke held his seminar “Ethics and Genetics” at MHH.
• on 28.04.03 and 05.05.03, Prof. Hedrich and colleagues gave a course on “Animal Experiments” at
MHH.
• From 04. – 05.04.03, the annual presentation workshop took place at the festival hall of the
Stephansstift Hannover. All students had to present and openly discuss their projects with the other
students, lecturers and supervisors. Separate student and supervisor meetings were organized. On
Friday, an international evening took place.
• On 16.05.03, a seminar organized by the company “Applied Biosystems” on “Gene expression and
SNP genotyping for human and mouse – Real-time PCR possibilities today and tomorrow” was
performed.
• The on-site evaluation by the accreditation committee was done on 24.06.03.
• Altogether 44 applicants were invited to interviews in Hannover, New Delhi (India; DAAD office)
and Hyderabad (India; CDFD) beginning of Juli 2003. The candidates had to give a short
presentation on a past or future project. In Hannover, the applicants were accomodated in the
“Sleep-In” guest house.
• From 14. – 15.07.03, the workshop on “Presentation techniques” took place at MHH (Frau PD Dr.
Dierks). The aim was to train students for giving annual presentations, conference talks etc.
• On 07.11.03, the first six final exams were sucessfully performed (public disputation, in English).
External referees were invited (Daeron, Paris; v. Weizäcker, Freiburg; Maurer, Mainz; Schröder,
Kiel; Virchow, Rostock; Grez, Frankfurt). Invited speaker: Prof. Dr. D. McConnell (Dublin,
Ireland). Musical introduction/ending: Herr Neuhäuser.
7. Travel
• Claudia Karacsonyi was granted a travel support for a congress in Göttingen (March 2003).
• From 05. – 07.05.03, Dr. S. Kruse and Prof. Dr. R.E. Schmidt were attending the “Jahrestagung der
DAAD geförderten PHD Programme” in Bonn.
• From 30.06. – 04.07.03, the MD/PhD students Ferdinand Bahlmann, Veit Erpenbeck, Julia Freise,
Marcel Mala, Anika Meyerholz and Axel Schambach were attending the meeting with nobel prize
holders in Lindau.
• From 03. - 07.07.03, Dr. S. Kruse, Prof. Dr. R. E. Schmidt und Prof. Dr. C. Klein were traveling to
India to give interviews with 22 applicants in the DAAD office New Delhi and at CDFD,
Hyderabad. From these applicants, 8 were selected for the program. In Hyderabad, contacts with
Prof. Dr. S. Hasnain were tightened.
• From 19. - 20.09.03, Dr. S. Kruse visited the general meeting of the Swiss MD/PhD society in
Basel.
• On 26.09.03, Dr. S. Kruse attended the annual meeting of the “Deutsche Gesellschaft für
Immunologie” in Berlin.
• From 27. - 28.10.03, Dr. S. Kruse was invited to give a talk on “marketing on demand” on the
GATE Workshop “Internationales Hochschulmarketing” in Bonn.
• From 08. – 09.12.03, Dr. S. Kruse and Prof. Dr. R.E. Schmidt attended the annual meeting of the
DAAD programs (IPP) in Bonn.
8. Visits abroad by the graduate students
• For three PhD students travel costs to Hannover were supported (October 2003). The other
students were supported from the “WIN” program (see above).
• Overall, the MD/PhD students attended numerous meetings, congresses and short research stays
abroad. They were supported by the departments, DAAD, DFG (Emmy Noether) etc.
16
Year 2000
Tanja Heller
Nadine Landgraf
Masami Rudolph
EducationCollege/University:1992-2000 Hannover Medical School andFac. de med. Montpellier
Highest degree:MD (Dr. med.)
Major Subjects:Medicine
Projects/Research: Complement systemToll like receptors, signal transduction
Scholarships:Studienstiftung des Deutschen VolkesEmmy Noether Stipendium DFG
Scientific Interests and Goals:Mechanisms of innate immuntity
Hobbies and other interests:Music, Sports, Travel
Publications:Heller T, Hennecke M, Baumann U, Gessner JE, zu Vilsendorf AM, et al. J Immunol. 1999; 163(2):985-94Heller T, Gessner JE, Schmidt RE, Klos A, Bautsch W, Kohl J. J Immunol. 1999; 162(10):5657-61
First name:Tanja
Last name:Heller
Date of birth:25.04.1973
Country:Germany
E-mail:[email protected]
Supervisor:Prof. R.E. SchmidtClinical Immunology
EducationCollege/University:1994-2000 School of Veterinary Medicine Hannover
Highest degree:Veterinarian
Major Subjects:Molecular Biology, Veterinary Medicine
Projects/Research:Myosin Mutation 723 Arg->Gly as one reason for FHC. Investigation on molecular level.
First name:Nadine
Last name:Landgraf
Date of birth:15.7.74
Country:Germany
E-mail:[email protected]
Supervisor:PD KraftMolecular and CellPhysiology
EducationCollege/University:1991-1997 Kyolin University1998-2000 Harvard Medical School
Highest degree: MD
Major Subjects:Molecular biology
Projects/Research:Molecular analysis of somatogenesis in mouse
Scientific Interests and Goals:Having own laboratory or biotechnology company
Hobbies and other interests:Swimming, Watching movies
Publications:Watabe-Rudolph M. Schlautmann N. Papaioannou VE. Gossler A. Mech Dev. 2002; 119:251-6.Watabe-Rudolph M. Rudolph KL. Averbeck T. Buhr T. Lenarz T. Stover T. Otol Neurotol. 2002; 23:793-8.
First name:Masami
Last name:Rudolph
Date of birth:06.05.1970
Country:Japan
Email:[email protected]
Supervisor:Prof. GosslerMolecular Biology
Year 2001
Wahid Ansari
Ferdinand Bahlmann
Asha Balakrishna
Christian Bernreuther
Frank Bollig
Marc H. Dahlke
Meta Djojosubroto
Julia Freise
Christoph M. Happel
Vladimira Jakubcakova
Yijiang Li
Jian-Yun Liu
Tom Lüdde
Ebru Serinsöz
Frank Tacke
Matthewos Tessema
Sonja Werwitzke
EducationCollege/University:Aligarh Muslim University, Aligarh Panjab University, Chandigarh
Highest degree:M.Sc. in Biotechnology
Major Subjects:Molecular Biology and Immunology
Projects/Research:Role of Natural Killer Cells in HIV-1 Infection
Scholarships:DBT-Govt. Of India fellowship-M.Sc programmeCSIR-Govt. Of India Junior Research FellowshipSFB 566-Teilproject A2
Scientific Interests and Goals:Immunobiology and Molecular Pathogenesis of Infectious Diseases.
Hobbies and other interests:Cricket, Music and Travelling
First name:Abdul Wahid
Last name:Ansari
Date of birth:16.02.1973
Country:India
E-mail: [email protected]
Supervisor:Prof. R E SchmidtDr. Hans HeikenClinical Immunology
EducationCollege/University:1994 – 2001 Hannover Medical School2000 – 2001 Tufts University, School of Medicine, Boston,
USA
Highest degree:MD (Dr. med.)
Projects/Research:Endothelial Progenitor Cells in Kidney Disease
Scientific Interests and Goals:To transfer basic science from bench to bedside
Publications:Bahlmann F, Janssen U, Kohl J, Zwirner J, Haubitz M, Floege J A J KidneyDis 2000; 35:21-28.Schratzberger P, Walter DH, Rittig K, Bahlmann FH, Pola R, et al.. J ClinInvest 2001; 107:1083-1092.Ostendorf T, Kunter U, Grone HJ, Bahlmann F, Kawachi H, et al. J Am Soc Nephrol 2001; 12:909-918.Walter DH, Rittig K, Bahlmann FH, Kirchmair R, Silver M., et al.Circulation 2002; 105:3017-3024.
Woywodt A, Bahlmann FH, De Groot K, Haller H, Haubitz, M. NephrolDial Transplant 2002; 17:1728-1730Dahlke MH, Popp FC, Bahlmann FH, Aselmann H, Jager MD, Neipp M,Piso P, Klempnauer J, Schlitt HJ. J Hepatol. 2003;39:365-73.Bahlmann FH, DeGroot K, Duckert T, Niemczyk E, Bahlmann E, BoehmSM, Haller H, Fliser D. Kidney Int. 2003;64:1648-52.Bahlmann FH, De Groot K, Spandau JM, Landry AL, Hertel B, Duckert T,Boehm SM, Menne J, Haller H, Fliser D. Blood. 2004;103:921-6.Bahlmann FH, de Groot K, Haller H, Fliser D. Nephrol Dial Transplant.2004;19:20-2.Bahlmann FH, deGroot, K., Sowa, J., Hertel, B.,Menne, J., Haller,H.,Fliser, D. Kidney Int. In pressBahlmann FH, Song, R. , Boehm, S.M., Mengel, M., von Wasielewski, R.,Lindschau, C., Kirsch, T., de Groot, K., Laudeley, R., Niemczyk, E., Gueler,G., Menne, J., Haller, H., & Fliser, D. Circulation in press
First name:Ferdinand Hermann
Last name:Bahlmann
Date of birth:24.03.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. HallerNephrology
EducationCollege/University:1995-98 Bhavans‘ Vivekananda College,
Secunderabad, India; B.Sc. (Genetics,Botany, Chemistry),
1998-2000 Sri Ramachandra Medical College andResearch Institute, Chennai, India;M.Sc.(HumanGenetics)
Highest degree:M.Sc.
Major Subjects:Human Genetics
Projects/Research:-Molecular genetics of Retinoblastoma-Secondary alterations in Mantle cell lymphomas
Scholarships:Scholarship from the „ Gesellschaft der Freunde der MHH“
Scientific Interests and Goals:I am interested in the analysis of a commonly deleted chromosomal region(1p22), in Mantle cell lymphomas and the search for tumor suppressor genes in this region.
Hobbies and other interests:Photography,Travelling, Music, Reading, Poetry
First name:Asha
Last name:Balakrishnan
Date of birth:15.03.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. SchlegelbergerCell and Molecular Pathology
EducationCollege/University:1994-1996 University of Hamburg, Physics1995-2001 University of Hamburg,Medicine
Highest degree: MD (Dr. med.)
Major Subjects:Molecular Biology, Neurobiology
Projects/Research:Influence of CAMs (L1, CHL1) on Differentiation/Regeneration in the Central Nervous System
Scholarships:Grant from TWS, Graduiertenkolleg
Hobbies and other interests:History, Geography, Sports, Close-Up-Magic
First name:Christian
Last name:Bernreuther
Date of birth:03.11.72
Country:Sweden
E-mail:[email protected]
Supervisor:Prof. C. GrotheNeuroanatomy
EducationCollege/University:1991-1999 Hannover Medical School
Highest degree:MD (Dr. med.)
Major Subjects:Molecular biology, inflammation
Projects/Research:Regulation of gene expression ininflammation
Scientific Interests and Goals:See projects/research above
Hobbies and other interests:Soccer, tennis, biking
Publications:Kafert S, Winzen R, Loos A, Bollig F, Resch K, Holtmann H. FEBS Lett. 1998; 421(1):2-6.Bollig F, Winzen R, Kracht M, Ghebremedhin B, Ritter B, Wilhelm A, Resch K, Holtmann H. Eur. J. Biochem. 2002; 269(23):5830-9.Bollig F, Winzen R, Gaestel M, Kostka S, Resch K, Holtmann H.Biochem Biophys Res Commun. 2003; 301(3):665-70
First name:Frank
Last name:Bollig
Date of birth:28.12.1970
Country:Germany
E-mail:[email protected]
Supervisor:Prof. HoltmannPharmacology
EducationCollege/University:1995-2000 Hannover Medical School2001/2002 Surgical Resident, MHH2003/2004 Research Fellow, Centenary Institute
University of Sydney
Highest degree:MD (Dr. med.)
Major Subjects:Hepatic Stem CellsMesenchymal Stem CellsImmunosuppression by antibodiesCD45
Projects/Research:• Bone marrow to hepatocyte plasticity models• Experimental immunosuppression by anti-CD45 mAbs• Liver regeneration by mesenchymal stem cells• Socio-demographic studies in living donation• Models for technical surgical questions
Scholarships:Educational Grant by the DFGInternal Grant by the MHH (HiLF)
Scientific Interests and Goals:Making stem cell therapy feasible
Latest Publications:Ko S, Dahlke MH, Lauth O, Jager MD, Deiwick A, et al. Exp Hematol. 2001; 29(3):339-44.Dahlke MH, Lauth OS, Jager MD, Roeseler T, Timrott K, et al. Blood. 2002;99(10):3566-72.Ko S, Jaeger MD, Dahlke MH, Nakajima Y, Schlitt HJ. Curr Mol Med. 2002; 2(3):249-55.Dahlke MH, Popp FC, Bahlmann FH, Aselmann H, Jaeger MD, Neipp M, Piso P Klempnauer J, Schlitt HJ. J Hepatol 2003; 39(3):365-73.Dahlke MH, Schlitt HJ. Liver Trans, 2003; 9(10):1100-1.Dahlke MH, Larsen S, Rasko JE, Schlitt HJ. Leuk Lymph 2004,45(2):229-36Dahlke MH, Larsen S, Popp FC, Schlitt HJ, Rasko JE. Liver Trans, 2004, in press
First name:Marc H.
Last name:Dahlke
Date of birth:17.09.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. SchlittDepartment for Surgery,University of Regensburg
EducationCollege/University: University of Indonesia; Jakarta, Indonesia
Highest degree: B.Sc. in Biology (with Honours)
Major Subjects:Human Biology (Genetics)
Projects/Research:The impact of telomere shortening, senescence signalling and telomerase on regeneration and cancer.
Scientific Interests and Goals:Telomere biology and cancer.To learn more about the role of telomerase and telomere in cancer initiation and progress.
Hobbies and other interests:Reading, watching movies and other live performances (music, operas, theater, dance).
Publications:Djojosubroto MW, Choi YS, Lee HW, Rudolph KL Telomeres and telomerase in aging, regeneration and cancer. Mol. Cells. 2003; 15: 164-175.
Yusuf I, Djojosubroto MW, Ikawati R, Lum K, Kaneko A, Marzuki S. AdvExp Med Biol. 2003; 531: 37-46.
Keenihan SH, Gramzinksi R, Ratiwayanto S, Hadiputranto H, Riberu W, Soebianto S, Rusjdy F, Syafruddin D, Kartikasari A, Djojosubroto M, et al.Adv Exp Med Biol. 2003; 531: 83-102.
First name:Meta
Last name:Djojosubroto
Date of birth:21.11.1975
Country:Indonesia
E-mail:[email protected]
Supervisor:PD Dr. med. KL RudolphDept. Gastroenterology, Hepatology, and Endocrinology
EducationCollege/University:1987- 1994 Gymnasium Langenhagen 1999-2001 Wayne State University School of Medicine,
Detroit, MI, USA1994- 2001 Hannover Medical School
Highest degree:MD (Dr. med.)
Major Subjects:Microbiology, Molecular Biology
Projects/Research:Pathogen-host interaction of Chlamydia trachomatis
Scholarships:DAAD
Scientific Interests and Goals:PhD-Degree, Investigation of the pathogen-host interactions in Chlamydia trachomatis induced arthritis on a molecular and product level.
Publications:Freise J, Gérard HC, Bunke T, Whittum-Hudson JA, Zeidler H, et al. Ann Rheum Dis. 2001; 60(2):140-5.Gérard HC, Freise J, Wang Z, Roberts G, Rudy D, et al. Microbes Infect. 2002; 4(1):13-22
First name:Julia
Last name:Freise
Date of birth:16.12.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. H. ZeidlerRheumatology
EducationCollege/University:University of Frankfurt/Main, Germany
Highest degree:MD (Dr. med.)
Major Subjects:Medicine, Cell Biology
Projects/Research:Induction of homologous recombination by site-specific meganucleases
Scholarships:Studienstifung des Deutschen Volkes (1993-2000)
Scientific Interests and Goals:Gene therapy, bone marrow failure syndroms
Hobbies and other interests:carpe diem
Publications:Kirin SI, Happel CM, Hrubanova S, Weyhermüller T, Klein C, Metzler-Nolte N; Dalton Transactions 2004; in pressHobmayer B, Snyder P, Alt D, Happel CM, Holstein TW. Cell Tissue Res2001; 304: 147-157Hobmayer B, Rentzsch F, Kuhn K, Happel CM, Cramer v Laue C, Snyder P,Rothbächer U, Holstein TW. Nature 2000; 407: 186-189
First name:Christoph M.
Last name:Happel
Date of birth:16.04.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. C. KleinPediatrical Hematologyand Oncology
EducationCollege/University:Faculty of Nature SciencesUniversity of P.J SafarikDepartment of Molecular Biology; Kosice, Slovakia
Highest degree:Dr. rer. nat. (RNDr.)
Major Subjects:Molecular biology, neurobiology, chronobiology
Projects/Research:Circadian RhythmsThe Role of PKCα in Circadian Rhythms
Scientific Interests and Goals:My aim is to improve myself in research, to be good scientist...
Hobbies and other interests:life, nature, travelling, music, ...
First name:Vladimira
Last name:Jakubcakova
Date of birth:09.09.1975
Country:Slovakia
E-mail:[email protected]
Supervisor:Prof.EicheleMax-Planck-Institute of Experimental Endocrinology
EducationCollege/University:1994-1999 Bachelor of Medicine Univ. in Xi‘An1999-2001 Master of Medicine Univ. in Xi‘An
Higest degreeM.B., M.Sc. in Medicine
Major subjectPulmonary Transplantation Immunology
Project /Research2003 - Suppression of MHC-Class II molecule up regulation by HMG-CoA reductase inhibitors in an allogeneic model of rat lung transplantation2002 - Tissue engineered carotids: immunological,histological and molecular characteristics
Scientific Interests and GoalsEvery aspect concerning the lungLung Transplantation & Transplant ImmunologyLung Preservation & Ischemia reperfusion injuryPulmonary Stem cell & Tissue EngineeringThoracic & Experiment Surgery
Hobbies and other interestsI have many hobbies, please visit my personal website, or leave message on my BBS.
First Name:Yijiang
Last name:Li
Date of birth:29.07.1976
Country:China
E-mail:[email protected]:www.ki.mycm.net
Supervisor:Prof. Axel Haverich
EducationCollege/University:1991-1996 Peking University Medicine
Highest degree:MD
Major Subjects:Immunology, molecular biology
Projects/Research:Transplantation tolerance induction
Scientific Interests and Goals:Pursuing a position as a research scientist, specifically in the area of transplantation tolerance induction.
Hobbies and other interests:Travel,running, music, chess
First name:Jian-Yun
Last name:Liu
Date of birth:25.12.1972
Country:China
E-mail:[email protected]
Supervisor:Prof. SchlittVisceral and Trans-plantation Surgery
EducationCollege/University:Hannover Medical School
Highest degree:MD (Dr.med.)
Major Subjects:Internal Medicine/Hepatology
Projects/Research:Cell cycle regulation in the liver, antiapoptotic pathways in liver injury
Scholarships:Award from „Studienstiftung des Deutschen Volkes“
Scientific Interests and Goals:Cell cycle regulation in the liver, antiapoptotic pathways in liverinjury
Hobbies and other interests:piano, soccer, travelling, meeting with friends, reading
Publications:Lüdde T, Kubicka S, Plumpe J, Liedtke C, Manns MP, Trautwein C. Oncogene 2001; 20(38):5264-78.Luedde T, Wuestefeld T, Trautwein C. Hepatology 2001; 34(6):1254-6.Luedde T, Liedtke C, Manns MP, Trautwein C. Eur Cytokine Netw. 2002; 13(4):377-83.Luedde T, Rodriguez M, Tacke F, Xiong Y, Brenner D, Trautwein C. Hepatology. 2003; 37(4):833-41
First name:Tom
Last name: Lüdde
Date of birth:30.03.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. TrautweinGastroenterologyand Hepatology
EducationCollege/University:Ankara University Medical Faculty
Highest degree:MD, Associate Prof. in Pathology
Major Subjects:Pathology, Molecular Pathology
Projects/Research:Quantitative expression of gene expression in differentmechanisms of early allograft damage after renaltransplantation
Scientific Interests and Goals:To have an insight to molecular pathology and combine thisknowledge for my future pathology practice focusing on hematological malignancies
Hobbies and other interests:Drawing, music, reading, travelling, volleyball
Publications:Serinsöz E, Ensari A. Turkish Journal of Gastroenterology 2000; 4(3): 267-274.Unal AE, Bayar S, Serinsoz E, Kocaoglu H. Hepatogastroenterology 2002; 49(44):556-7.Yorganci A, Serinsoz E, Ensari A, Sertcelik A, Ortac F.Gynecol Oncol. 2003 Aug;90(2):478-81.Serinoz E, Varli M, Erden E, Cinar K, Kansu A, Uzunalimoglu O, Yurdaydin C, Bozkaya H. J Clin Gastroenterol. 2003 Mar;36(3):269-72.Bock O, Serinsoz E, Neusch M, Schlue J, Kreipe H. Br J Haematol. 2003 Nov;123(3):472-4.Li Z, Schwieger M, Lange C, Kraunus J, Sun H, van den Akker E, Modlich U, Serinsoz E, Will E, von Laer D, Stocking C, Fehse B, Schiedlmeier B, Baum C. Exp Hematol. 2003 Dec;31(12):1206-14.Bock O, Serinsoz E, Schlue J, Kreipe H.Leuk Res. 2004 May;28(5):457-60.Bock O, Schlue J, Mengel M, Busche G, Serinsoz E, Kreipe H.J Pathol. 2004 May;203(1):609-15
First name:Ebru
Last name:Serinsöz
Date of birth:15.01.1972
Country:Turkey
E-mail:[email protected]
Supervisor:Prof. KreipePathology
EducationCollege/University:1994-2001 Hannover Medical School1998-1999 University of Texas MD Anderson Cancer Center2000 Baylor College of Medicine, Houston, TX
Highest degree:Dr. med.
Major Subjects:Internal Medicine, Immunology, Hepatology, Virology
Projects/Research:Influence of mutations in the Hepatitis B Virus genome on virus replication and drug resistance (PhD thesis)Humoral regulation of thrombopoiesis and its clinical impact in patients with chronic liver diseases and in healthy volunteers (MD thesis)Gene transfer of inducible Bcl-Xs in myeloid leukemia (research scholarship at MD Anderson Cancer Center, Houston, TX, USA, 1998-1999)
Scholarships:1998-1999 DAAD-Funding
Scientific Interests and Goals:Molecular understanding of the basic virology of hepatitis B virus replication and of clinical problems such as drug resistance or fulminant hepatitisDefining the impact of cytokine dysregulation for the clinical course and complications in patients with chronic liver disease
Hobbies and other interests:Music, travel, art, literature, sports, party!
Publications:Tacke F, et al. Br J Haematol 1999; 105(2):511-513Tacke F, et al. Blood Coagul Fibrinolysis 2001; 12(7):539-545Schöffski P, Tacke F, et al. Liver 2002; 22:114-120Tacke F, et al. Liver 2002; 22:205-212 Tacke F, et al. J Hepatol 2003, 38(4):447-454Luedde T, Rodriguez M, Tacke F, et al. Hepatology 2003, 37(4):833-841Tacke F, et al. Blood Coagul Fibrinolysis 2003, 14(4):319-325Streetz KL, Tacke F, et al. Hepatology 2003, 38(1):218-229Tacke F, et al. Cancer Biol Ther 2004, 3(3)Tacke F, et al. Scand J Gastroenterol 2004 (in press)Tacke F, et al. Current Medicinal Chemistry 2004 (in press)
First name:Frank
Last name:Tacke
Date of birth:10.07.1973
Country:Germany
E-mail:[email protected]
Supervisors:Prof. Dr. C. TrautweinGastroenterology,Hepatology & Endocrinology
EducationCollege/University:1992 – 1998 DVM, Veterinary Medicine Addis Ababa
University1999 – 2001 MSc., Animal Pathology, Utrecht University
Highest degree:DVM, MSc.
Major Subjects:Cancer genetics, Host-pathogen interaction
Projects/Research:DNA methylation patterns in Myelodysplastic syndromes (MDS)
Scholarships:Nuffic: Netherlands University Fellowships Programme
Scientific Interests and Goals:My area of interest is cancer genetics and I am particularly interested in finding molecular targets for diagnosis and therapy of cancer.
Hobbies and other interests:Music, literature, movies and football
Publications:Mathewos Z, Getachew A, Yilma J. Revue. Méd. Vét. 2001, 152, 851-858.Tessema MZ, van Tongeren SE, Doresstein GM. Eur. J. Vet. Pathol. 2000, 6, 121-124.Tessema MZ, Koets AP, Rutten VPMJ, Gruys E. Vet. Quart. 2001, 23, 153-162.Tessema M, Länger F, Dingemann J, Ganser A, Kreipe H, Lehmann U. Leukemia 2003; 17(5):910-8Tessema M, Lehmann U, Kreipe H. Virchows Arch. 2004; 444(4):313-23.
First name:Mathewos
Last name:Tessema
Date of birth:27.01.73
Country:Ethiopia
E-mail:[email protected]
Supervisors:Prof. KreipeDr. LehmannPathology
EducationCollege/University:1994-2001 Studies of Medicine; Hannover Medical School1997-2001 MD thesis (Basic immunology)
Highest degree:MD (Dr. med.)
Major Subjects:Immunology, Rheumatology, Molecular Biology
Projects/Research:- New therapeutic approaches and
pathogenesis of autoimmune diseases- Interaction of immune complexes with Fc receptors- Differentiation and functional characterization of CD8β+ T cells
Scholarships:Grant from Hannover Medical School (HiLF programe)
Hobbies and other interests:Sports and photography
Publications:Werwitzke S, Drescher B, Schmidt RE, Witte T. Immunobiology 2000, 202:168-171Witte T, Werwitzke S, Schmidt RE. Immunobiology 2000, 202:194-198Werwitzke S, Tiede A, Drescher BE, Schmidt RE, Witte, T. Clinical andExperimental Immunology 2003, 133:334-43Werwitzke S, Tiede A, Stoll M, von Depka M. Journal of Thrombosis and Haemostasis 2004, 2:193-4
First name:Sonja
Last name:Werwitzke
Date of birth:10.12.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. R.E. SchmidtClinical Immunology
Year 2002
Diya Abraham
Syed Raza Ali
Johannes Beckermann
Georg Bohn
Thomas Gebhardt
Shashi Kant
Claudia Karacsonyi
Axel Karow
Varsha Kumar
Gesa Meyer
Anika Meyerholz
Christina Nassenstein
Axel Schambach
Aravind Sekhar
Amar Deep Sharma
Srinivas Annavarapu Rao
Krishna Kumar Singh
Manvendra Singh
Frank Traub
Linding Wang
EducationCollege/University:1999 B.Sc.-University of Mysore, India2001 M.Sc.-University of Mysore, India
Highest degree:M.Sc. in Biochemistry
Major Subjects:Microbiology, Zoology, Botany
Projects/Research:Analyzing the in vivo function of protein kinase C byusing mutant mice (knock outs).
Scholarships:1. Gold medallist in Master of Science2. Venkataraman Aarthie award
Scientific Interests and Goals:My main field of interest is Genetics and Molecular Biology.With the expertise I gain from these fields I would like tocontribute to the upliftement of mankind and society and alsounderstand to certain extent the great complexity of life.
Hobbies and other interests:Singing, Dancing, Cooking, Interior decoration, Reading,Flower arrangement
First name:Diya
Last name:Abraham
Date of birth:15.07.1979
Country:India
E-mail:[email protected]
Supervisor:Dr. M. LeitgesMax-Planck-Institutefor ExperimentalEndocrinology
EducationCollege/University:1999-2001 University of Pondicherry, India
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:Molecular characterization of complement-mediated FcγR gene regulation as an amplification loop of the innate immune response to immune complexes.
Scholarships:1. Awarded By DBT, India for selecton in All India Combined M.Sc. Biotechnology Program (1999-2001).2. Junior Research Fellowship awarded by Council for Scientific and Industrial Research, India (July, 2001).3. Grant from the „Gesellschaft der Freunde der MHH“ for my doctorate study.
Scientific Interests and Goals:To study the regulatory aspects of transcription at the level of protein-DNA interaction.
Hobbies and other interests:Music, travel and cricket
First name:Syed
Last name:Raza Ali
Date of birth:08.07.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. GessnerClinical Immunology
EducationCollege/University:1996-2002 in Marburg, London, Hannover
Highest degree:MD (Dr. med.)
Major Subjects:Nephrology
Projects/Research:UPA/UPAR in endothelial progenitor cells
Scholarships:DAAD
Scientific Interests and Goals:Signal transduction, endothelial progenitor cells, internalmedicine, clinical nephrology
First name:Johannes
Last name:Beckermann
Country:Germany
E-mail:[email protected]
Supervisor:Prof. DumlerNephrology
EducationCollege/University:1994-1997 Albert Ludwigs Universität Freiburg1997-1998 Universidad de Salamanca, Spain1998-2002 Technische Universität München
Highest degree:MD (Dr. med.)
Major Subjects:Medicine
Projects/Research:Identification and characterization of three novel auxiliary γsubunits of voltage gated calcium channelsGeneration and characterization of hematopoietic stem cell lines as novel tools to investigate genetic and developmental aspects of congenital bone marrow failure syndromes
Scientific Interests and Goals:Identification and characterization of yet undefined congenital bone marrow failure syndromes and the genuine role of hematopoietic stem cells in the development and differentiation of the hematopoietic system
Hobbies and other interests:Music, opera and exhibitions, cooking
Publications:Klugbauer N, Dai S, Specht V, Lacinova L, Marais E, Bohn G, Hofmann F. FEBS Lett 2000; 470: 189-197Bohn G, Moosmang S, Conrad H, Stieber J, Ludwig A, Biel M, Klugbauer N, Hofmann F. JPN J Electrcardiol 2000; 20: 76-78Bohn G, Moosmang S, Conrad H, Ludwig A, Hofmann F, Klugbauer N. FEBSLett 2000; 481: 73-76Moosmang S, Bohn G, Conrad H, Ludwig A, Biel M, Klugbauer N, Hofmann F (2001) “Molecules contributing to cardiac pacemaker current” in Morad M, Kostyuk P Calcium Signaling (IOS Press): 262-264
First name:Georg
Last name:Bohn
Date of birth:25.02.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. KleinPediatrical Hematologyand Oncology
EducationCollege/University:Hannover Medical School
Highest degree:MD (Dr. med.)
Projects/Research:Regulation of mast cells by cytokinesMast cell-nerve interactions
Hobbies and other interests:Jogging, Collecting records, Travelling
Publications:Zender L, Kock R, Eckhard M, Frericks B, Gosling T, Gebhardt T, DrobekS, Galanski M, Kuhnel F, Manns M, Kubicka S. Gastroenterology. 2002; 123:608.Gebhardt T, Sellge G, Lorentz A, Raab R, Manns MP, Bischoff SC. Eur J Immunol. 2002; 32:2308Bedoui S, Lechner S, Gebhardt T, Nave H, Beck-Sickinger AG, Straub RH, Pabst R, von Horsten S. J Neuroimmunol. 2002; 132:25.Lorentz A, Klopp I, Gebhardt T, Manns MP, Bischoff SC. J Allergy Clin Immunol. 2003; 111:1062.Sellge G, Lorentz A, Gebhardt T, Levi-Schaffer F, Bektas H, Manns MP, Schuppan D, Bischoff SC. J Immunol. 2004; 172:260.
First name:Thomas
Last name:Gebhardt
Date of birth:02.04.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. S.C. BischoffGastroenterology,Hepatology, and Endocrinology
EducationCollege/University:2000-2002 School of Biotechnology, Madurai Kamarej University, Madurai, India
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:Mechanisms of activation and substrate targeting in the MAP kinase cascadesCotransformation of multiple T-DNAs: Segregation analysis in the T1generationHydrophobic conserved residues of homeodomains
Scholarships:Have received DBT (Department of Biotechnology) studentship for 2years during my M.Sc.Have received educational stipend during my B.Sc. under rural experience program.
Scientific Interests and Goals:I am interested in the study of molecular mechanisms of activation of MAP kinase cascade and it´s target proteins.
Publications:Kant S, Bagaria A, Ramakumar S.Biochem Biophys Res Commun. 2002; 299(2):229-32.
First name:Shashi
Last name:Kant
Date of birth:10.07.1976
Country:India
E-mail:[email protected]@mh-hannover.de
Supervisor:Prof. Dr. M. GaestelPhysiological Biochemistry
EducationCollege/University:University of Buenos Aires
Highest degree:M.Sc. in Biochemistry
Major Subjects:Biochemistry / Biotechnology
Projects/Research:•The role of lipid rafts in the antigen presentation pathway. Hannover Medical School, Germany.•Design of a transfer vector for the production of recombinant AgMNPV. IBBM, U of La Plata, Argentina.(2002)•Design of an Enzyme immune assay for the detection of GADA. Department of Immunology, U of Buenos Aires, Argentina.(2001-2002)•Study of different mutations in the ccr5 gen and their relationship with HIV-1. Department of Genetics, U of Buenos Aires, Argentina.(1999)
Scholarships:CADIE studentship for an interchange course at the University of Massachusetts, Amherst.
Scientific Interests and Goals:To become a doctor and continue my education in the researchfield.
Hobbies and other interests:Travel, sports, cinema
First name:Claudia Victoria
Last name:Karacsonyi
Date of birth:04.10.1977
Country:Argentina
E-mail:[email protected]
Supervisor:Dr. LindnerCell Biology
EducationCollege/University:1995-2002 Hannover Medical School
Highest degree:MD (Dr.med.)
Major Subjects:Microbiology, Pediatrics
Projects/Research:Enterohemorrhagic Escherichia coliAcute lymphoblastic leukemia
Scientific Interests and Goals:My main interest is to contribute to further insight into antileukemic immunity
Hobbies and other interests:Running, travel, soccer, literature
First name:Axel
Last name:Karow
Date of birth:16.10.1974
Country:Germany
E-mail:[email protected]
Supervisor:Prof. KleinPediatrical Hematology And Oncology
EducationCollege/University: 2000-2002 Madurai Kamaraj University
Highest degree:M.Sc. in Biochemical Technology
Major Subjects:Immunology
Projects/Research:Analysis of the coupling mechanism between C5a anaphylatoxinand FcγRs in Ab-dependent models of nephritis and autoimmune hemolytic anemia
Scholarships:Graduiertenkolleg (GK 705)
Scientific Interests and Goals:Unravelling the molecular aspects of diseases, thus contributingtowards research in medicine.
Hobbies and other interests:painting, travelling, reading books and an avid animal lover
First name:Varsha
Last name:Kumar
Date of birth:28.01.80
Country:India
E-mail:[email protected]
Supervisor:Prof. Gessner JEClinical Immunology
EducationCollege/University:1995-2003 School of Veterinary Medicine Hannover, Germany
Highest degree:MD
Major Subjects:Toxicology, Cell Biology
Projects/Research:Molecular mechanisms of the inflammatory response of mast cells and colonocytes induced by Clostridium difficile toxins A and B: analysis of toxin-induced pro-inflammatory signal cascades.
Scientific Interests and Goals:To get further insights into the pathogenesis of intestinal inflammation induced by bacterial toxins using molecular and immunological techniques
Hobbies and other interests:Everything related to music: playing the violin, dancing…
First name:Gesa
Last name:Meyer
Date of birth:17.03.1976
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. JustInstitute of ToxicologyHannover Medical School
EducationCollege/University:1995-2002: Hannover Medical School, Human medicine
Highest degree:MD (Dr. med.)
Major SubjectsInternal medicine, cell biology
Projects/Research:Role of CALM in clathrin dependent transport mechanisms
Scientific Interests and Goals:My main interest is the influences of transport processes during the developm4ent of haematological malignancies
Publications:Umeda A, Meyerholz A, Ungewickell E. Eur J Cell Biol. 2000; 79(5): 336-42.
First name:Anika
Last name:Meyerholz
Date of birth:22.05.1976
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. UngewickellCell biology
EducationCollege/University:1995-2002 Albert-Ludwigs-University Freiburg, Germany
Highest degree:MD
Major Subjects:(Neuro-) Immunology, Allergology, Pneumology
Projects/Research:Mechanisms of Neurogenic Inflammation in Allergic Asthma: TheRole of the Neurotrophin Receptors TrkA, TrkB, TrkC und p75NTR
Scientific Interests and Goals:To get further insights to the pathogenesis of allergic asthma as well as neuro-immune interaction using physiological, immunological and molecular techniques in diverse in-vitro and in-vivo test-systems.
Hobbies and other interests:My big fat horse “Fly“; Literature
Publications:Virchow JC Jr, Faehndrich S, Nassenstein C, Bock S, Matthys H, Luttmann W.Clin Exp Allergy. 2001 Jun;31(6):836-44Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, Luttmann W, Renz H, Virchow JC jr. J Exp Med. 2003 Aug 4;198(3):455-67Nassenstein C, Kerzel S, Braun A. Prog Brain Res. 2004;146:347-67
First name:Christina
Last name:Nassenstein
Date of birth:24.04.1976
Country:Germany
E-mail:[email protected]
Supervisor:Dr. BraunFraunhofer-Institute ofToxicology and Experi-mental Medicine
EducationCollege/University:1995-2001 University of Hamburg, Medicine2001 Scripps Research Institute (USA), UCSF (USA)
University of Zürich (Switzerland)
Highest degree:MD (Dr. med.)
Major Subjects:Hematology, Virology, Molecular Biology
Projects/Research:Regulation of Gene Expression in Retroviral VectorsGenetics of Lipid Metabolism
Scholarships:1996-2001 Scholarship „Studienstiftung des Deutschen
Volkes“
Scientific Interests and Goals:Molecular origin of diseases. Connection of basic scienceapproaches with clinical applications. Gene therapy,transplantation.
Hobbies and other interests:Beach Volleyball, Soccer, Travel
Publications:Ries S, Buchler C, Schindler G, Aslanidis C, Ameis D, et al. Hum Mutat.1998; 12 (1): 44-51.Wodrich H, Schambach A, Krausslich HG. Nucleic Acids Res. 2000,284(4): 901-10Schambach A, Wodrich H, Hildinger M, Bohne J, Krausslich HG, BaumC. Mol Ther. 2000, 2(5): 435-45.
First name:Axel
Last name:Schambach
Date of birth:27.08.74
Country:Germany
E-mail:[email protected]
Supervisor:Prof. BaumHematology
EducationCollege/University:1996-2002 Bangalore Medical College, Bangalore
Highest degree:M.B.B.S.(Bachelor of Medicine & Surgery)
Major Subjects:Medicine, Surgery, Obstetrics & Gynaecology
Projects/Research:Genes specifically expressed in intestine epithelium
Scholarships:JNCASR Summer Research Fellowship `98
Scientific Interests and Goals:Developmental biology
Hobbies and other interests:Travel, Reading, Rock Music, Calligraphy
First name:Aravind
Last name:
Sekhar
Date of birth:19.04.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. GosslerMolecular Biology
EducationCollege/University:J.N.U. New Delhi, India
Highest degree:M.Sc. in Bioechnology
Major Subjects:Cell Biology, Immunology and Molecular Biology
Projects/Research:Differentiation of adult as well as embryonic stem cells into hepatocytes.
ScholarshipsDepartment of Biotechnology in India
Scientific Interests and Goals:I am interested in stem cell biology and want to exploretheir potential for therapeutic purposes.
Hobbies and other interests:Watching cricket matches
First name:Amar Deep
Last name:Sharma
Date of birth:21.02.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. OttGastroenterology, Hepatology andEndocrinology
EducationCollege/University:1992-1997 M.B.B.S; Dr S.N Medical College, Jodhpur, India1998-2001 MD Pathology; AFMC, Pune, India2001 Diplomate National Board (DNB) Pathology
Highest degree:MD Pathology ; DNB Pathology
Major Subjects:Pathology, Hematology and Oncology
Projects/Research:Gastrointestinal stromal tumours: A Light microscopic, Ultrastructuaral & Immunohistochemical Correlation of 30 cases.Redifferentiation stratergies for thyroid cancer
Scientific Interests and Goals:To translate molecular research into clinical diagnostics and therapeutics
Hobbies and other interests:Guitar, Cars, Travel and Cricket
Publications:Mishra DK, Rai R, Rao AS. Indian J. Hematol.& Blood Transf. 1999; 17: 20 Rao A, Mishra DK, Subramanya H. Indian J. Hematol.& Blood Transf. 2000; 18: 90-94.
First name:Srinivas
Last name:Annavarapu Rao
Date of birth:08.06.1973
Country:India
E-mail:[email protected]
Supervisor:Prof. BrabantEndocrinology
EducationCollege/University:1995-98 Udai Pratap College/ Purvanchal University1998-1999 Benaras Hindu University 1999-2001 Goa University
Highest degree:M.Sc. in Biotechnology
Major Subjects:Cell and Molecular Biology, Biochemistry, Biophysics, Immunology, Microbiology and Genetic Engineering
Projects/Research:Genetics of retinal drusen formation in Rhesus Macaques.
Scholarships:Grant from the Pro Retina.
Scientific Interests and Goals:I want to pursue my research in the field which has somedirect effect in medical sciences.
Hobbies and other interests:Music, Novels, Cricket and Chess
First name:Krishna Kumar
Last name:Singh
Date of birth:02.10.1977
Country:India
E-mail:[email protected]
Supervisor:Prof. SchmidtkeHuman Genetics
EducationCollege/University:2000-2002 Madurai kamaraj University M.Sc in Biotechnology.
Highest degree:M.Sc. in Biotechnology
Major Subjects:Biotechnology
Projects/Research:1. Construction of antisense vector to studythe process of Melaninbiosynthesis and UV induced inflammation.2. Production, purification, characterization and comparative study of a protease from a thermophilic fungi Thermomycese lanuginosus.
Scholarships:1. Awarded by DBT,india for selection in All india combined M.Sc. biotechnology programe (2000-2002).2. Junior Research Fellowship (JRF) awarded by Council for Scientific and Industrial Research (CSIR), India.3. R&D Assistantship from JNCASR, Bangalore, India.
Scientific Interests and Goals:My main field of interest is Developmental Biology, I want tostudy the biology of Somite and Limb Patterning. I would consider myself to be successful in my ambition if I am in any way able to add to the knowledge that will ultimately help us tounderstand this fascinating area of biology better.
Hobbies and other interests:Music, Cricket, Movies, literature, etc.
First name:Manvendra
Last name:Singh
Date of birth:02.01.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. KispertMolecular Biology
EducationCollege/University:1995-2001 Philipps University Marburg (Germany)2001-2002 University of Pretoria (South Africa) 2002 Pritzker School of Medicine Chicago (USA)
Highest degree:MD
Major Subjects:Microbiology, Cell Biology, Proteomics
Projects/Research:Influence of BMP-2 on human bone marrow cellsProteinprofile of human breast cancer
Scholarships:Forschungspool der Universität Marburg (2000)
Scientific Interests and Goals:Tumor growth and development
Hobbies and other interests:swimming, handball, economics, travelling
Publications:Wilke A., Traub F., Kienapfel H., Griss P. Biochem Biophys Res Commun. 2001; 284:1093-7.
First name:Frank
Last name:Traub
Date of birth:19.08.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. KreipePathologie
EducationCollege/University:Anhui UniversityShanghai Institute of Biological Products
Highest degree:M.Sc. in Pathogenic Microbiology & Molecular Biology
Major Subjects:Cloning and expression of HIV-1 gag p24, env gp41 recombinantantigens and p24-gp41 fusion recombinant antigen in Escherichiacoli
Projects/Research:FunctiofFunctional characterization of M-type K15 of Kapos’s Sarcoma-Associated herpesvirus
Scholarships:DAAD
Scientific Interests and Goals:Molecular biology and virology;grasp the highest standardtechniques and serve the people
First name:Linding
Last name:Wang
Date of birth:12.04.1973
Country:China
E-mail:[email protected]
Supervisor:Prof. SchulzVirology
Year 2003
Khaled Alkasah
Tammy Chang
Anuhar Chaturvedi
Dorothea Dijkstra
Dorothea Gadzicki
Jaba Gamrekelashvili
Arnab Ghosh
Shipra Gupta
Eric Hesse
Kumaravelu Jagavelu
Gustavo Salguero Lopez
Harini Nivarthi
Andri Pramono
Rahul Purwar
Bishnudeo Roy
Tibor Veres
Anastassiia Vertii
Ajit K. Yadav
EducationCollege/University:1992-1996 BSc in Medical Laboratories, Sana´a University, Yemen.
Highest degree:MSc in Medical Microbiology, Sana´a University, Yemen.
Major Subjects:Microbiology, Haematology and Biochemstry.
Projects/Research:Viral and Genetic Detreminants of KSHV/HHV-8 Transmission from Mother to Child.
Scholarships:DAAD
Hobbies and other interests:Swimming and other sports
First name:Khaled
Last name:Alkharsah
Date of birth:08.01.1975
Country:Syria
E-mail:[email protected]
Supervisor:Prof. Dr. T. F. Schulz Virology
First name:Tammy
Last name:Chang
Date of birth:16.10.1975
Country:Taiwan (R.O.C.)
E-mail:Tammy_CYS@ web.de
Supervisor:Prof. TümmlerKlinische Forschergruppe“Molecular Pathology of Cystic Fibrosis”
Education
College / University:
1995-1997 Phillipps University Marburg, Germany
1997-2003 Justus-Liebig University Gießen, Germany
Highest degree:
Dipl. oec. troph.
Major Subjects:Biochemistry of Nutrition, Nutrition in developing countries
Project / Research:
Pseudomonas aeruginosa – mammalian host cell interaction: Phagocyte-sensitizing genes of P. aeruginosa
Scientific Interests and Goal:Genotypic and phenotypic characterization of baterial fitnessand virulence factors in Pseudomonas using biochemical, biological and/or biophysical assays
Hobbies and other interests:There are a lot of other things outside the lab which are also to be discovered. But above all, the one who created all things on earth, is of most interest.
Publications:Iozef R, Rahlfs S, Chang T, Schirmer H, Becker K. FEBS Letters 2003 Oct;554:284-288
EducationCollege/University:B. Pharm - June 1997 to July2001 Department of Pharmaceutical
Sciences and Drug Research, Punjabi University Patiala, Punjab India.
MS (Pharm) Biotechnology - July 2001 to Dec 2002National Institute of Pharmaceutical Education and Research ,
Mohali, Punjab. India
Highest degree:MS(Pharm)
Major Subjects:Pharmacology, Pharmaceutics, Biotechnology
Projects/Research:Functional genomics using RNA-interference in hematopoietic
cells
Scientific Interests and Goals:Functional analysis of individual signaling molecules by means
of RNAi in primary normal and malignant hematopoietic cells thus to find targets for therapeutic interventation.
Scholarships1. Awarded by National Institute of Pharmaceutical
Education and Research for MS(Pharm) in Biotechnology-July 2001 to Dec 2002
2. Junior Research Fellowship awarded by Council of Scientific and Industrial Research India (Dec, 2002 )
3. Grant from Deutsche Forschungsgemeinschaft for my doctorate study
Hobbies and other interests:Movies, Travelling and cooking
Publications:Review ArticleShruti Agarwal, Anuhar Chaturvedi, Nilanjan RoyPharmacogenomics –The concept behind Personalized Medicine.Current Research and Information in Pharmaceutical SciencesVol. 3 No. 3 July - September 2002
First name:Anuhar
Last name:Chaturvedi
Date of birth:31.12.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. Matthias EderHematology and Oncology
First Name:Dorothea (Dorrit)
Last Name:Dijkstra
Date of Birth:28.10.1977
Country:The Netherlands
E-mail:[email protected]
Supervisors:Prof. Dr. T. WerfelDr. R. GutzmerDermatology
Education College/University:1995-1999 Hogeschool IJsselland, Deventer, The
Netherlands1999-2001 Vrije Universiteit, Amsterdam, The
Netherlands
Highest degree:MSc (Drs.)
Major Subjects:Immunology, Dermatology, Pharmacology
Scientific Interests and Goals:To find out the role of anaphylatoxins C3a and C5a and their respective receptors in modulating the interaction between dendritic cells and T-lymphocytes in the skin. We will compare healthy subjects and patients with chronic inflammatory skin diseases as a model.
Hobbies and other interests:Parasitology (fascinating how they escape from host immune responses!), World Wildlife Foundation, Windsurfing, Skating, Friends, Drawing, Reading, Music, my parents dog Rocaille etc.
EducationCollege/University:1994-2001 Medizinische Hochschule Hannover, Germany
Highest degree:MD
Major Subjects:Genetics, Tumorigenesis
Projects/Research:Identification of secondary genetic changes in BRCA1/2-induced hereditary breast cancer development
Scientific Interests and Goals:To gain insight into fundamental molecular processes during breast cancer development, in particular of hereditary breast cancer, to improve the diagnostic procedures and adapt therapeutic strategies for a better prognostic outcome.
Hobbies and other interests:Literature, theatre, sports, drawing
Publications:D.Gadzicki, K.Müller-Vahl, M.Stuhrmann Molecular and Cellular Probes 1999; 13:321-323
D.Gadzicki, KR.Müller-Vahl, D.Heller, S.Ossegge, M.M.Nöthen, J.Hebebrand, M.Stuhrmann Am J Med Genet (published online 10 Feb 2004)
First name:Dorothea
Last name:Gadzicki
Date of birth:07.10.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. Dr. med. Brigitte Schlegelberger,Cell and Molecular Pathology
EducationCollege/University:1996-2002 Tbilisi State Medical University, Tbilisi Georgia
Highest degree:MD
Major Subjects:Basic and tumor Immunology
Projects/Research:Influence of tumor cell death on tumor specific immune response
Scientific Interests and Goals:To clarify mechanisms of immune tolerance & activation in tumor immunity
Hobbies and other interests:Table tennis, football, neuroscience.
Publications:Nizharadze N, Gongadze M, Sanikidze T, Gamrekelashvili J, Sumbadze C, Kevlishvili O. Proc. Georgian Acad. Sci., Biol., Ser. A., 2002, 28: 573-576.
First name:Jaba
Last name:Gamrekelashvili
Date of birth:07.01.1979
Country:Georgia
E-mail:[email protected]
Supervisor:PD.Dr. T. GretenDepartment of Gastroenterology,Hepatology & Endocrinology
EducationCollege/University:1996-2001 Mysore Medical College, India
Highest degree:MBBS
Major Subjects:Medicine
Projects/Research:Mechanisms and modulation of anti-leukemia immunity
Scientific Interests and Goals:To obtain further insights into management of childhood leukemia
Hobbies and other interests:Exploring Indian wildlife; Anthropology and development oflanguages
First name:Arnab
Last name:Ghosh
Date of birth:09.05.1978
Country:India
E-mail:[email protected]
Supervisor:Prof. KleinPediatric Hematology and Oncology
EducationCollege/University:1998-2003: All India Institute of Medical Sciences (AIIMS), New Delhi, India
Highest degree:M.Biotech.
Major Subjects:Biotechnology, Molecular Biology, Immunology
Projects/Research:Generation and characterization of chemokine-derived peptides leading to the inactivation of chemokine receptors on
inflammatory cells
Scientific Interests and Goals:To know more about chemokines
Hobbies and other interests:Painting
First name:Shipra
Last name:Gupta
Date of birth:27.08.1979
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. J. ElsnerDermatology
EducationCollege/University:1996-2003 Hannover University Medical School, Germany
Harvard University Medical School, U.S.A.University of Birmingham, GBUniversity of Otago, New ZealandUniversity of Zurich, SwitzerlandUniversity of Cape Town, South Africa
Highest degree:MD (Dr. med.)
Major Subjects:Cell Biology, Genetics, Tissue Engineering
Projects/Research:Gene- expression analysis of mesenchymal stem cells and theirmatrix- synthesis under functional aspects
Scientific Interests and Goals:Differentiation and characteristics of mesenchymal stem cells
Scholarship:Scholarship Foundation, Bayer Leverkusen AGDAADHannelore Munke Research Award
Hobbies and other interests:Sports (Jogging, Motorcycling, Swimming), Travelling, all my friends, Literature, good wine and food
Publications:Musholt PB, Hesse E, Musholt TJ, Petrich T, Pötter E, Oetting G, et al. ClinChem Lab Med 2001; 39:171.
Hesse E, Musholt PB, Petrich T, Pötter E, Lichtinghagen R, Musholt TJ, Knapp WH. Eur J Nucl Med Mol Imaging 2002; 29:183.
First name:Eric
Last name:Hesse
Date of birth:09.10.1975
Country:Germany
E-mail:[email protected]
Supervisor:Prof. M. v. GriensvenExperimentalTraumatology
EducationCollege/University:1997-1999 Bharathidasan University, Trichy, India
Highest degree:M.Sc.
Major Subjects:Microbiology
Projects/Research:Functional analysis of Tbx8 in muscle development.
Scientific Interests:To study the molecular aspeccts and signalling mechanisms of organ development.
Hobbies and other interests:Photography, Lepidoptery, Travelling
Publications:Kumaravelu J, Shanmugasundaram GK, Unwala H, Ramamoorthi N, Banerjea AC. Genes and Immunity 2001; 2, 404-407.
Ramamoorthi N, Kumaravelu J, Shanmugasundaram GK, Rani K, Banerjea AC. Genes and Immunity 2001; 2, 408-410.
First name:Kumaravelu
Last name:Jagavelu
Date of birth:08.03.1976
Country:India
E-mail:[email protected]
Supervisor:Prof.Dr KispertMolecular Biology
EducationCollege/University:1995-2001 Universidad Nacional de Colombia, Bogota Colombia
Highest degree:MD
Major Subjects:Cellular and molecular biology of cardiovascular diseases: Cellular and molecular mechanisms of angiogenesis.Role of progenitor cells in neovascularization
Projects/Research:Impact of biomechanical stretch in progenitor cell differentiation. Role of progenitor cells in Hypertension
Scientific Interests and Goals:My main goal is to apply the knowledge from research in molecular biology on the understanding of cardiovascular diseases. As a first approach I am working on in vitro and in vivomodels of vascular hypertension at a cellular and molecular level. It will open me new perspectives about potential applications of molecular technology and their impact on diagnostic and prevention strategies and more specific and effective treatments for these kind of diseases.
Hobbies and other interests:Take a walk by the mountains. Good music and literature.
First name:Gustavo
Last name:Salguero
Date of birth:11.07.1978
Country:Colombia
E-mail:[email protected]
Supervisor:PD. Bernhard SchiefferCardiology and Angiology
EducationB.Sc. Biochemistry, Daulat Ram College, Delhi Univrsity.M.Sc. Biotechnology, Madurai Kamaraj University
Highest degree:Master
Major Subjects:Biotechnology, Biochemistry
Projects/Research:Molecular analysis of transcription factors involved in dendritic cell developmernt
Hobbies and other interests:Reading, Indian classical dance.
First name:Harini
Last name:Nivarthi
Date of birth:15.08.1980
Country:India
E-mail:[email protected]
Supervisor:Prof. Dr. KleinPediatric Hematology and Oncology
EducationCollege/University:1999 B.Sc. University of Indonesia, Indonesia2003 M.Sc University of Indonesia, Indonesia
Highest degree:M.Sc. in Microbiology Medicine
Major Subjects:Cell Biology,Virology, Molecular Biology
Projects/Research:In vitro Hematopoietic Differentiation of Embryonic Stem Cells Using Gene Modified Vectors
Scientific Interests and Goals:My interest is unravelling the mechanism of hematopoiesis in embryonic stem cell and genetic control behind this
Hobbies and other interests:Playing Piano, travelling, watching movie
First name:Andri
Last name:Pramono
Date of birth:21.08.1976
Country:Indonesia
E-mail:[email protected]
Supervisor:Prof. Dr. K. WeltePediatrics
EducationCollege/University:Lucknow UniversityAll India Institute of Medical Sciences, New Delhi, India
Highest degree:M.Sc( Biochemistry)
Major Subjects:Biochemistry, Immunology
Projects/Research:T cell - keratinocyte interaction in chronic inflammatory skin
diseases
Scientific Interests and Goals:Doing good research in the field of Immunogy
Hobbies and other interests:Reading, Cricket
First name:Rahul
Last name:Purwar
Date of birth:05.12.1977
Country:India
E-mail:[email protected]
Supervisor:Prof.Dr. M. WittmannProf. Dr. T.WerfelDermatology
EducationCollege/University:2001-2003 School of Biotechnology, Madurai Kamaraj University, Madurai, India
Highest degree:MSc in Biotechnology
Major Subjects:Biotechnology
Projects/Research:Contribution of B1 cells to the gut associated humoral immunity.
Scholarships •Received DBT (Department of Biotechnology, India) studentship during my MSc.• Junior research fellowship (JRF) awarded by Counsil for Scientific and Industrial Research (CSIR), India
Scientific Interests and Goals:I Have a particular interest in understanding the complexity of the regulation of immune responses.
First name:Bishnudeo
Last name:Roy
Date of birth:04.08.1978
Country:India
E-mail:[email protected]
Supervisor:Dr. S. WeissMolecular ImmunologyGBF
EducationCollege/University:1996-2003 Semmelweis University Budapest, Hungary
Highest degree:MD
Major Subjects:Immunology, Neuroimmune Interactions, Respiratory Medicine
Projects/Research:Interaction between pulmonary dendritic cells and nerves during allergic airway inflammation
Scientific Interests and Goals:To reveal locations and mechanisms of cross-talk between the nervous and immune system and investigating the contribution of neuroimmune interactions to allergy
Hobbies and other interests:Music, literature, languages, hiking
Publications:Vannay A, Fekete A, Muller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabo AJ. Kidney Blood Press Res. 2004
First name:Tibor
Last name:Veres
Date of birth:11. 06. 1978
Country:Hungary
E-mail:[email protected]
Supervisor:Dr. BraunFraunhofer-Institute forToxicology and Experi-mental Medicine
EducationCollege/University:1993-1998 Kharkov State University -Kharkov, Ukraine2001-2003 Kadir Has University-Istanbul, Turkey
Highest degree:MSc
Major Subjects:Molecular Biology, Protein Interaction, Heat Shock Proteins
Projects/Research:Search for biological functions of Hsp25 phosphorylation
Scientific Interests and Goals:To understand the role of Hsp25 phosphorylation inthermoresistance and translational inhibition, particularly in Hsp25interaction with translation factors and Akt/PKB
Hobbies and other interests:Alpine skiing; Lab mice and Street cats
Publications:Memon A., Aktoprakligil D., Ozdemir A., Vertii A. Turk J. Bot 2001; 25:11-121
First name:Anastassiia
Last name:Vertii
Date of birth:03.08.1976
Country:Ukraine
E-mail:[email protected]
Supervisor:Prof. Dr. M. GaestelDr. A. KotlyarovPhysiological Chemistry
EducationCollege/University:2001-2003Jawaharlal Nehru University, New Delhi, India.
Highest degree:M.Sc in Biotechnology
Major Subjects:Molecular Biology
Projects/Research:Master Thesis; Stabilization of proteins by solvent engineering:Lysozyme as a modelCurrent Ph.D project: Characterization of biochemical pathways implicated in production of varieties of xylose containing glycans
Scholarships:Scholarship sponsored by DBT, India for Master education (2001-2003).Junior Research Fellowship (2003), awarded by ICMR, India.Presently, GK705 Fellowship for my Ph.D study.
Scientific Interests and Goals:I am interested in xylosylation of cytoplasmic proteins. My current project focused on to find out different pathways leads to production of various xylose containing glycans. I am also interested in dessecting out the role of xylose moieties on various glycan modified proteins.
First name:Ajit
Last name:Yadav
Date of birth:07.07.1980
Country:India
E-mail:[email protected]
Supervisor:Dr. Hans BakkerProf. Dr. R. Gerardy-SchahnCellular Chemistry
Faculty
Jürgen Alves Norbert Krug (Fraunhofer Institut)
Rudolph Bauerfeind Jens Kuipers
Christopher Baum Tosso Leeb (TiHo)
Rainer Blasczyk Ulrich Lehmann
Jan Buer (GBF) Robert Lindner
Olaf Dammann Nisar Peter Malek
Helmut Drexler Heiner Niemann (TiHo, Mariensee)
Matthias Eder Bernhard Schieffer
Greogor Eichele (MPI) Brigitte Schlegelberger
Reinhold Förster Reinhold Ernst Schmidt
Matthias Gaestel Jörg Schmidtke
Engelbert Gessner Thomas F. Schulz
Achim Gossler Reinhard Schwinzer
Florian Gunzer Beate Sodeik
Carlos Alberto Guzmann (GBF) Jürgen Strehlau
Hermann Haller Manfred Stuhrmann-Spangenberg
Hansjörg Hauser (GBF) Christian Trautwein
Denise Hilfiker Burkhard Tümmler
Helmut Holtmann Ernst Ungewickell
Roland Jacobs Claus Urbanke
Ingo Just Sigfried Weiss (GBF)
Andreas Kispert Karl Welte
Christoph Klein Thomas Werfel
Andreas Klos Miriam Wittmann
Alexey Kotlyarov Anna M. Wobus (IPK Gatersleben)
Department and function:Professor, Biophysical Chemistry
Education:1975 – 1981 University of Hannover, Biochemistry1981 – 1984 PhD thesis
Positions:1984 – 1990 Postdoc Hannover Medical School1990 – 1995 PD Hannover Medical School1995 - Prof. Hannover Medical School
Major research interests:Protein design using different model systems:• Restriction endonuclease EcoRI• IS1 Transposase• Helikase I• DynaminCircular Dichroism Spectroscopy
Selected Publications:Windolph S, Fritz A, Oelgeschlaeger T, Wolfes H, Alves J. Biochemistry 1997; 36: 9478-9485.Kalthoff C, Alves J, Urbanke C, Knorr R, Ungewickell EJ. J Biol Chem 2002, 277:8209-16.Scheele U, Alves J, Frank R, Duwel M, Kalthoff C, Ungewickell E. J Biol Chem. 2003; 278(28):25357-68.
First name:Jürgen
Last name:Alves
Acad. Title:Prof. Dr. rer. nat.
Address:OE 4350Hannover Medical School
Phone and e-mail:++49-0511-532 [email protected]
Further information:http://www.mh-hannover.de/institute/bpc
Department and function:Group Leader, Cell Biology
Education:1991 Dr. rer. nat. in Biology, University of Bonn
Positions:1991-94 Postdoc at EMBL + University of Heidelberg1994-97 Postdoc at Yale University School of MedicineSince 1997 Group leader at Hannover Medical School
Major research interests:Endocytosis and Signal Transduction in the Nervous SystemThe goal of our laboratory is to understand the cellular and molecular basis of communication between neurons in the mammalian nervous system.To communicate neurons use chemical signals that are stored and transported in membrane bound vesicles.Endocytosis, a fundamental process common to all eucaryotic cells, plays a central role in the formation of the vesicles. We are studying the function of endocytosis in neuronal signaltransduction and the molecular components which form endocytic transport vesicles in neurons.
Selected Publications:Bauerfeind et al. J. Biol. Chem. 1997; 272: 30984-92Bauerfeind et al. Adv. Pharmacol. 1998; 42: 253-7
First name:Rudolf
Last name:Bauerfeind
Acad. Title:Dr. rer. nat.
Address:OE4130Hannover Medical School
Phone and e-mail:++49-511 532 [email protected]
Further information:www.mh-hannover.de/institute/zellbiologie/RudisWeb/Home.htm
Department and function:Professor, Hematology and Oncology
Education:1981-1982 Philosophy 1982-1989 Medicine
Positions:1989-1991 Research Clinics, Borstel b. Bad Oldesloe1991-1992 Toxicology, Univ. of Hamburg1993-1999 Heinrich-Pette-Institute Hamburg 2000 University Hospital Eppendorf, Hamburg2000 - MHH, Dept. Hematology and Oncology2002 Cincinnati Children‘s Hospital Adjunct Position
Major research interests:Cell TherapyGene Transfer and TherapyRetrovirusesGene expressionStem Cell BiologyBiology of cell selection and clonal evolution
Oncogenesis
Selected Publications:Li Z, et al. Science 2002, 296:497.Wahlers A, et al. J Virol 2002, 76: 303-312.Schieldmeier B, et al. Blood 2003, 101:1759-1768.Baum C, et al. Blood 2003, 101:2099-2114.Williams DA, Baum C. Science. 2003; 302(5644):400-1. Engels B, et al. Hum Gene Ther. 2003; 14(12):1155-68Li Z, et al. Exp Hematol. 2003 Dec;31(12):1206-14
First name:Christopher
Last name:Baum
Acad. Title:Prof. Dr. med.Adjunct Associate Prof. of Pediatrics
Address:OE 5120Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/haemonko/cb_research.htm
Department and function:Director, Transfusion Medicine
Education:1981-1987 Universities of Bochum and Essen, Medicine1996 Specialist in Transfusion Medicine
Positions:1987-1988 University of Marburg, Surgery1988-1991 University of Essen, Immunology1992-1993 University of Duesseldorf,
Hematology and Oncology1993-1998 Humboldt-University of Berlin,
Transfusion Medicine1998 Hannover Medical School,
Professor for Transfusion Medicine
Major research interests:MHC diversity and diversificationImmunology of allogeneic stem cell transplantationImmunology of Graft versus Host and Graft versus Tumor effects
Selected Publications:Elsner HA, Rozas J, Blasczyk R. Immunogenetics 2002; 54: 447-62.Elsner HA, Blasczyk R. Eur J Immunogenet 2002; 29: 229-36Seltsam A, Hallensleben M, Kollmann A, Blasczyk R. Blood. 2003; 102(8):3035-42. Elsner HA, DeLuca D, Strub J, Blasczyk R. Bone Marrow Transplant. 2004; 33(2):165-9. Elsner HA, Blasczyk R. Tissue Antigens. 2004; 63(2):109-21.Khattab B, Eiz-Vesper B, Ganser A, Hertenstein B, Blasczyk R. Ann Hematol. 2004; 83(2):107-13.
First name:Rainer
Last name:Blasczyk
Acad. Title:Prof. Dr.
Address:OE 8350Hannover Medical School
Phone and e-mail:++49 -511- 532 [email protected]
Further information:www.mh-hannover.de/institute/transfusion
Department and function:Professor, Mucosal Immunity, GBF
Education:1987-1994 Medicine in Hannover and New York, 1995 Approbation, Doctor of Medicine, 2001 Habilitation in Immunology,
Positions:1998-present Head of Mucosal Immunity (GBF), 1998-present Institute of Medical Microbiology (MHH), 1996-1998 DFG-Fellowship in Immunology, Hôpital Necker-
Enfants Malades, Paris, France,1995-1996 Resident in Internal Medicine, Department of
Hematology and Oncology (MHH),
Major research interests:My current work on mucosal immunity concentrates on functional genomics of regulatory T cells in transgenic mouse models and patients with autoimmunity and inflammation. Other interests are Host-Pathogen-Crosstalk and Molecular Diagnostics.
Selected Publications:Buer J, AifantisI, DiSanto JP, Fehling HJ, von Boehmer H J. Exp. Med. 1997; 185:1541-1547.Buer J, Lanoue A, Franzke A, Garcia C, von Boehmer H, Sarukhan A. J. Exp. Med. 1998; 187: 177-183.Lechner O, Lauber J, Franzke A, Sarukhan A, von Boehmer H, Buer J. Curr. Biol. 2001; 11: 587-595.Buer J, Balling R. Nature Reviews Genetics 2003; 4: 195-205.Franzke A, Piao W, Lauber J, Gatzlaff P, Konecke C, et al. Blood. 2003; 102:734-9.
First name:Jan
Last name:Buer
Acad. Title:Prof. Dr. med.
Address:GBF-MIMascheroder Weg 138124 Braunschweig
Phone and e-mail:[email protected]
Further information:www.gbf.de
Department and function:Head, Perinatal Infectious Disease Epidemiology UnitObstetrics, Prenatal Medicine, and General GynecologyPediatric Pulmonology and Neonatology
Education:1981-83 Linguistics, U of Hamburg, 1983-90 Medicine, Med U of Lübeck and U of Hamburg,
Epidemiology,1996-97 Harvard School of Public Health,
Positions:1991-95 Post-Doc, Pediatrics, U of Hamburg1995-97 Post-Doc, Neuroepidemiology, Children‘s Hospital,
Boston,1997-2000 Instructor in Neurology, Harvard Med School,since 2000 Assistant Professor in Neurology, Harvard Med School, since 2002 Professor of Perinatal Infectiology, Hannover Med.
School
Major research interests:Epidemiologic research on the role of infection and inflammation in theetiology and pathogenesis of brain white matter damage in pretermnewborns
Selected Publications:Dammann O, Leviton A. Pediatric Research 1997;42:1-8.Dammann O, Leviton A. Current Opinion in Pediatrics 2000;12:99-104.Dammann O, Durum S, Leviton A. Trends in Neurosciences 2001; 24:320-4.Dammann O, Allred EN, Genest DR, Kundsin RB, Leviton A. Paediatric and Perinatal Epidemiology 2003;17:49-57.Dammann O, Drescher J, Veelken N. Developmental Medicine & Child Neurology 2003;45:148-51.Jung H, Neumaier Probst E, Hauffa BP, Partsch CJ, Dammann O. J Clin Endocrinol Metab. 2003 Oct;88(10):4590-5. Dammann O, Leviton A. Ann Neurol. 2004 Feb;55(2):158-161.Dammann O, Allred EN, Van Marter LJ, Dammann CE, Leviton A. Pediatr Res. 2004; 55(2):319-325.
First name:Olaf
Last name:Dammann
Acad. Title:Prof. Dr.med., M.Sc.
Address:OE6415Hannover Medical School
Phone and e-mail:++49-511- 532 [email protected]
Further information:http://www.mh-hannover.de/forschung/perinatalinfektiologie/index.htm
Department and function:Director, Cardiology and Angiology
Education:1970 – 1976 Medical School, Univ. of Freiburg1986 Habilitation
Positions:1989-1996 Associate Professor University of Freiburg1990 – 1994 Heisenberg Award and InvestigatSept. 1996 Professor of Medicine, Chief of Cardiology, Medical
University, Hannover
Major research interests:Endothelial FunctionMolecular Mechanisms of cardiac hypertrophy and adaption to stressInflammation in arteriosclerosi
Selected Publications:Schieffer B, Schieffer E, Hilfiker-Kleiner D, Hilfiker A, Kovanen PT, et al. Circulation. 2000 Mar 28;101(12):1372-8.Schieffer B, Luchtefeld M, Braun S, Hilfiker A, Hilfiker-Kleiner D, et al. Circ Res. 2000; 87(12):1195-201Fiedler B, Lohmann SM, Smolenski A, Linnemüller S, Pieske B, et al. Proc Natl Acad Sci USA 2002;99:11363-11368Hornig B, Kohler C, Schlink D, Tatge H, Drexler H. Hypertension 2003; 41(5):1092-5Spiekermann S, Landmesser U, Dikalov G, Bredt M, Gamez G, et al. Circulation 2003; 107: 1383 - 1389Heineke J, Kempf T, Kraft T, Hilfiker A, Morawietz H, et al. Circulation 2003; 107: 1424 - 1432Podewski E.K., Hilfiker-Kleiner D., Hilfiker A., Morawietz H., Lichtenberg A., et al. Circulation 2003; 107: 798-802Schieffer B, Drexler H. J Am Coll Cardiol. 2003;41(11):1962-3.Wollert KC, Drexler H. Eur Heart J. 2003; 24(24):2164-5.
First name:Helmut
Last name:Drexler
Acad. Title:Prof. Dr.
Address:OE 6880Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/kardiologie/index.html
Department and function:Professor, Hematology/Oncology unit; Consultant Bone marrow transplantation
Education:1982-89 Study of Medicine, Homburg/S and
Frankfurt/M1990 Doctoral thesis1989-91 Research assistant and fellow Int. Med.1991-93 Research fellow Dana Farber Cancer Inst., Boston1993-2000 Research fellow Int. Med. Frankfurt + MHHSince 2001 Habilitation, consultant Int. Medicine
Positions:1991-1993 Dana Farber Cancer Institute, Boston1993-1996 Johann Wolfgang v.Goethe University
FrankfurtSince 1996 MHH
Major research interests:Signal transduction by cytokine receptors in myeloid cellsModels for myeloproliferative disorders and acuteleukemiaLentiviral gene transferRNA interference
Selected Publications:Kafert S, Luther S, Böll I, Wagner K, Ganser A, Eder M. J.Biol. Chem 1999. 274:33064Wagner K, Kafert-Kasting S, Heil G, Ganser A, Eder M. Blood 2001, 98: 2681Scherr M, Battmer K, Blömer U, Schiedlmeier B, Ganser A, Grez M, Eder M. Blood2002, 99:709Scherr M, Battmer K, Winkler T, Heidenreich O, Ganser A, Eder M.. Blood 2003,101:1566Scherr M, Morgan MA, Eder M. Curr Med.Chem 2003, 10: 245Tiede A, Eder M, von Depka M, Battmer K, Luther S, et al. Gene Ther. 2003; 10(22):1917-25. Scherr M, Steinmann D, Eder M. Ann Hematol. 2004; 83(1):1-8.
First name:Matthias
Last name:Eder
Acad. Title:Prof. Dr. med.
Address:OE 6860Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/kliniken/haemonko/index.htm
Department and function:Director, Molecular Embryology, MPI
Education:1980 Ph.D. University of Basel1981-1984 Postdoctoral training University of California,
San Francisco
Positions:1985-1989 Assistant Professor, Harvard Medical School, Boston1989-1990 Associate Professor, Harvard Medical School, Boston1991-1992 Associate Professor, Baylor College of Medicine,
Houston1992- Professor of Biochemistry and Neuroscience,
Baylor College of Medicine,Houston1997 A. Romansky Professor of Biochemistry1998- Director at the Max-Planck-Institute of Experimental
Endocrinology, Hannover
Major research interests:Developmental BiologyFunctional GenomicsNeurobiologyCircadian rhythms
Selected Publications:Sun ZS, Albrecht U, Zhuchenko O, Bailey J, Eichele G, LeeCC. Cell 1997; 90: 1003-1011.Albrecht U, Sun Z, Eichele G, Lee CC. Cell 1997; 91: 1055-1064.Reymond A, Marigo V, Yaylaoglu MB, Leoni, A, Ucla C, et al. Nature 2002;420: 582-586.Carson JP, Thaller C, Eichele G Current Opinion in Neurobiology 2002;12: 562-565.Moeller C, Swindell EC, Kispert A, Eichele G. Development. 2003;130(21):5103-11. Visel A, Thaller C, Eichele G. Nucleic Acids Res. 2004 Jan 1;32
First name:Eichele
Last name:Gregor
Acad. Title:Prof. Dr. Phil.
Address:Max-Planck Insitutefor Experimental Endocrinology,Hannover
Phone and e-mail:++49-511- 5359 [email protected]
Further information:http://www.endo.mpg.de/
Department and function:Director, Immunology
Education:1981 Abitur, Gymnasium Pegnitz1988 DVM, Munich, Veterinary Faculty1988 - 1991 Ph.D. Thesis
Positions:1991-93 Postdoc, Insitute of Biochemistry, University of Munich1994-00 Research Associate, Max-Delbruck-Center for
Molecular Medicine, Berlin2000-01 Associate Professor for Experimental Surgery and
Immunology, University of Erlangen2001 – Director and Head, Institute of Imunology, Professor for
Immunology
Major research interests:Chemokines and chemokine receptors, role in lymphoid organorganogenesis and organization, development of immunology memory,cell migration, tumor metastasis
Selected Publications:Forster R., Mattis A. E., Kremmer E., Wolf E., Brem G., Lipp M. Cell 1996 87:1037Forster R., Schubel A., Breitfeld D., Kremmer E., Renner-Muller I., et al. Cell 199999:23 Breitfeld D., Ohl L., Kremmer E., Ellwart J., Sallusto F., et al. J Exp Med 2000192:1545Henning G., Ohl L, Junt T., Reiterer P., Brinkmann V., et al. J Exp Med 2001;194:1875Ohl L., Henning G., Krautwald S., Lipp M., Hardtke S., et al. J Exp Med 2003;197:1199Pabst O., Ohl L., Wendland M., Wurbel M.A., Kremmer E., et al. J Exp Med. 2004
First name:Reinhold
Last name:Förster
Acad. Title:Prof. Dr. med. vet
Address:OE5240Hannover Medical School
Phone and e-mail:[email protected]
Department and function:Director, Biochemistry (Physiological Chemistry)
Education:1983 PhD in Biology (Biophysics), Humboldt-University
Berlin1993 Habilitation in Biochemistry, Free University Berlin
Positions:1991-1995: Junior Research Group Leader at the Max-Delbrück-
Centrum for Molecular Medicine (MDC), Berlin-Buch1995-1997: Heisenberg-Fellow of the German Research Council
(DFG), Guest Research Group Leader at the MDC,Berlin-Buch
1997-2000: Professor of Molecular Genetics; Innovationskolleg"Zellspezialisierung" of the Martin-Luther-UniversityHalle-Wittenberg
2001-recent: Chair and Head of Institute of Biochemistry/ Physiological Chemistry of Hannover Medical School
Major research interests:Analysis of mechanisms of stress-dependent signal transductionNucleo-cytoplasmic signallingRegulation of gene expression by protein phosphorylation at the post-transcriptional level
Selected Publications:Kotlyarov A., Neininger A., Schubert C., Eckert R., Birchmeier C., et al. Nature Cell Biol. 1999; 1: 94-97.Neininger A., Thielemann H, Gaestel M. EMBO Rep. 2001; 2: 703-708.Neininger A., Kontoyiannis D., Kotlyarov A., Winzen R., Eckert R., et al. J. Biol. Chem. 2002; 277: 3065-3068.Kotlyarov A., Yannoni Y., Fritz S., Laaß K., Telliez J.-B., et al. Mol. Cell. Biol. 2002; 22: 4827-4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21): 7732-7741.
First name:Matthias
Last name:Gaestel
Acad. Title:Prof. Dr.
Address:OE 4310Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/biochemie
Department and function:Group Leader, Laboratory of Molecular Immunology; ClinicalImmunology
Education:1993 PhD in Chemistry and Molecular Biology, Technical
University (TU) Berlin1999 Habilitation in Immunology, Hannover Medical School
Positions:1994-1996: Research Associate, Dept. of Clinical Immunology,
Hannover Medical School 1994: Visiting Scientist, Dept. of Immunology, University of
Utrecht, The Netherlands1997: EMBO Research Fellow, Dept. of Pathology, CMU
Geneva, Switzerland1997-recent: Research Group Leader, and from 2002 on, Scientific
Director and Head of the Laboratory of Molecular Immunology at the Department of Clinical Immunology, Hannover Medical School
Major research interests:I) Analysis of molecular mechanisms underlying immunoregulation during disease development in gene knockout mice.II) Signal transduction of G-protein coupled receptors.III) Gene regulation of IgG Fc receptors and their targeting for the establishment of new therapeutic strategies.
Selected Publications:Meyer D. et al. Blood 1998; 92:2997-4002.Schiller C. et al. Eur J Immunol. 2000; 30:481-490.Baumann U. et al. J Immunol. 2000; 164:1065-1070.Baumann U. et al. J Immunol. 2001; 167:1022-1027.Chouchakova N. et al. J Immunol. 2001; 166:5193-5200.Heusohn F. et al. J Immunol. 2002; 168:2857-2864.Radeke HH. et al. J Biol Chem. 2002; 277:27535-27544.Shushakova N. et al. J Clin Invest. 2002; 110:1823-1830.Nieswandt B. et al. Int Immunol. 2003; 15:341-349.
First name:J. Engelbert
Last name:Geßner
Acad. Title:Prof. Dr. rer.nat.Dr. hum.biol.habil.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/immun
Department and function:Director, Molecular Biology
Education:1982 B.S. Eberhard-Karls-University, Tübingen,) 1983 M.S. Friedrich-Miescher-Laboratory (FML) of
the Max-Planck-Society, Tübingen1986 Ph.D. Max-Planck-Society, Tübingen1987 - 1989 Postdoc at the Mount Sinai Hospital Res.
Institute, Toronto, Canada
Positions:June 1989- July 1994 Head of an independent research group at
Max-Delbrück-Lab., Cologne, GermanyApril 1994 Habilitation: University of Cologne Aug. 1994 - July 1997 Associate Staff Scientist, The Jackson
Laboratory, Bar Harbor, MEAug. 1997 - June 1999 Staff Scientist , The Jackson Laboratorysince July 1999 Professor for Molecular Biology, MHH
Major research interests:The main research interest of the group lies on the analysis of the molecular mechanisms underlying developmental processes during mammalian embryogenesis. Development of the Notochord The notochord is a transient embryonic structure that serves as a signaling center that is essential for the dorsoventralpatterning of the spinal cord and somites. Various mutations in mice disturb the development or maintenance of the notochord. Identification and functional characterization of the genes affected by these mutations is the subject of several projects. Somitogenesis Somites form as the result of segmentation of the paraxial mesoderm. They give rise to the vertebrae, ribs, the epaxial and hypaxialmuscles and the dorsal dermis. Their formation lays the basis for the metameric arrangement of the vertebrae and of the spinal ganglia. The formation of segments as well as their subdivision into cranial and caudal compartments is the subject of our investigations. We analyse the role of Notch signalling in these processes as well as spontaneous mouse mutants in which somitogenesis is disrupted.
Selected Publications:Jouve C., Palmeirim I., Henrique D., Beckers J., Gossler A., et al. Development 2000; 127: 1421-1429.Beckers J., Schlautmann N., Gossler, A. MOD 2000; 95: 35-46.Beckers J, Caron A, Hrabê de Angelis M, Hans S, Campos-Ortega JA, Gossler A.MOD 2000; 95: 23-34.Watabe-Rudolph M, Schlautmann N, Papaioannou VE, Gossler A. MOD 2002; 119:251-256Aulehla A, Wehrle C, Kemler R, Mallo M., Gossler A., Kanzler B, Herrmann BG. Dev. Cell 2003; 4: 395-406Serth K, Schuster-Gossler K, Cordes R, Gossler A.Genes and Development 2003; 17(7):912-25
First name:Achim
Last name:Gossler
Acad. Title:Prof. Dr.
Address:OE 5250Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/institute/molekularbiologie/
Department and function:Group Leader, Medical Microbiology
Education:1983 – 1990 Medical School in Würzburg, Bonn and Köln1991 – 1993 MD thesis
Positions:1994 – 1996 Postdoc, Tufts University, BostonFrom 1996 Research associate, Institute of Medical Microbiology,
Hannover Medical School
Major research interests:-Virulence of enterohemorrhagic E. coli and pathogenicity of EHEC-infections-Microbe/host interactions in EHEC-disease-Development of diagnostic tools for detection of bacterial pathogens
Selected Publications:Gunzer F, Hennig-Pauka I, Waldmann KH, Sandhoff R, Gröne HJ, et al. Am.J.Clin.Pathol. 2002; 118:364-375.Gunzer F, Hennig-Pauka I, Waldmann KH, Mengel M. Methods Mol.Med. 2003;73:307-327.Pulz M, Matussek A, Monazahian M, Tittel A, Nikolic E, et al. J Clin Microbiol. 2003; 41(10):4671-5. Matussek A, Lauber J, Bergau A, Hansen W, Rohde M, et al. Blood. 2003; 102(4):1323-32
First name:Florian
Last name:Gunzer
Acad. Title:MD (Dr. med.)
Address:OE 5210Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:http://www.mh-hannover.de/institute/mikrobiologie/
Department and function:Head Vaccine Research Group, Microbial Pathogenesis and Vaccine Research, Division of Microbiology, GBF
Education:1976-1981 Medicine, National University Rosario, Argentina1982-1986 Specialisation in Bacteriology, Rosario, Argentina 1988 MD, University of Genoa, Italy1989 Qualifying Medical Graduates Examination, School of
Medicine and Surgery, Genoa, Italy1993 PhD in Microbiology, University of Genoa, Italy2000 Habilitation Medical Microbiology, Hanover Medical
School
Positions:Since 1994 Head Vaccine Research, GBF, Braunschweig, Germany1991 - 1993 Laboratory of Microbial Pathogenesis, Univ. Genoa, Italy1989 - 1991 Division of Microbiology, GBF, Braunschweig, Germany1986 - 1989 Institute of Microbiology, Genoa, Italy1982 - 1986 National University of Rosario, Argentina1982 - 1986 Italian Hospital, Rosario, Argentina1982 - 1986 Children Hospital, Rosario, Argentina
Major research interests:Vaccinology, mucosal immunity, development of antigen delivery systems and adjuvants.
Selected Publications:Guzmán C A, Talay S R, Molinari G, Medina E., Chhatwal GS. J. Infect. Dis 1999;179:901-906.Medina E, Molinari G, Rohde M, Hasse B, Chhatwal GS, Guzmán CA. J. Immunol. 1999; 163:3396-3402.Medina E, Paglia P, Rohde M., Colombo M.P, Guzmán CA. Eur. J. Immunol. 2000;30:768-777.Drabner B, Borsutzky S, Winckler U, Morr M, Ensoli B, et al. Eur. J. Immunol. 2002; 32:2857-2865Schulze K, Medina E, Chhatwal GS, Guzman CA. Vaccine. 2003; 21:1958-64. Borsutzky S, Fiorelli V, Ebensen T, Tripiciano A, Rharbaoui F, et al. Eur J Immunol. 2003 Jun;33(6):1548-56. Schulze K, Medina E, Chhatwal GS, Guzman CA. Infect Immun. 2003; 71(12):7197-201.
First name:Carlos Alberto
Last name:Guzman
Acad. Title:MD, PhD
Address:GBFMascheroder Weg 138124-Braunschweig
Phone and e-mail:[email protected]
Department and function:Director, Nephrology; Chairman, Department of Internal Medicine
Education:1972-1982 Chemistry, Art History, Medicine in
Tübingen, Berlin and Cardiff
Positions:1992-1996 Assistenzarzt FU Berlin1996-1999 Postdoctoral Fellowship Yale University1992-1997 Professor of Medicine, Franz-Volhard-Klinik
at the Max Delbrück Centre, Berlin1999 Professor of Medicine, MHH
Major research interests:I am interested in acute and chronic changes of the vasculature. I have started in analysing signal transduction pathways in vascular smooth muscle cells and gradually moved into endothelial cells. Additionally, I am interested in vascular development, circulating endothelial progenitor cells and stem cells in the kidney.
Selected PublicationsMaasch C, Wagner S, Lindschau C, Alexander G, Buchner K, et al. FASEB J 2000; 14(11):1653-1663.Drab M, Verkade P, Elger M, Kasper M, Löhn M, et al. Science 2001; 293 (5539): 2449-2452.Radermacher J, Chavan A, Bleck J, Vitzthum A, Stoess B, et al. N Engl J Med. 2001; 344(6):410-417.Woywodt A, Streiber F, de Groot K, Regelsberger H,Haller H, Haubitz M. Lancet2003; 361(9353):206-210.Radermacher J, Mengel M, Ellis S, Stuht S, Hiss M, et al. N Engl J Med. 2003; 349(2):115-24Woywodt A, Schroeder M, Gwinner W, Mengel M, Jaeger M, et al. Transplantation. 2003; 76(1):1-4Fiebeler A, Park JK, Muller DN, Lindschau C, Mengel M, et al. Am J Kidney Dis. 2004 Feb;43(2):286-95
First name:Hermann
Last name:Haller
Acad. Title:Prof. Dr.
Address:OE 6840Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:[email protected]
Department and function:Head, Gene Regulation and Differentiation And Division of Molecular Biotechnology, GBF
Education:1969-1974 University of Stuttgart-Hohenheim, Food technology1974-1977 PhD thesis at University of Konstanz, Biology
Positions:1978-1980 Post-Doc at MPI f. Molecular Genetics, Berlin and
DKFZ, Heidelberg1981- Research fellow, group leader, head of dept.,
head of division, GBF, Braunschweig
Major research interests:1. Signal transduction in the cytokine system (signalling molecules
and their impact on transcription, cellular and systemic consequences)
2. Biotechnology with mammalian cells (protein production, viral vectors, cellular vaccines)
Selected Publications:Kirchhoff S., Hauser H. Oncogene 1999; 18: 3725-3736Nourbakhsh M, Hauser H. EMBO J. 1999; 18:101-111Kröger A, Ortmann D, Krohne TU, Blum H., Hauser H, Geissler M. Cancer Res.2001, 61, 2609-2617Unsinger J, Kröger A, Hauser H, Wirth D. Molecular Therapy 2001; 4: 484-489Meraro D, Gleit-Kielmanowicz M, Hauser H, Levi B-Z. J. Immunology 2002; 168:6224-6231Feng X, Guo Z, Nourbakhsh M, Hauser H, Ganster R, et al. Proc. Natl. Acad. Sci.USA 2002, 99: 14212-14217Kröger A, Dallügge A, Kirchhoff S., Hauser H. Oncogene 2003, 22:1045-1056
First name:Hansjörg
Last name:Hauser
Acad. Title:Dr. rer. nat
Address:GBFMascheroder Weg 138124 Braunschweig
Phone and e-mail:++49 [email protected]
Further information:www.gbf.de
Department and function:Group Leader, Molecular Cardiology (Cardiology and Angiology)
Education:1994 PhD in Biology (Genetics and Developmental Biology),
University of ZürichZürich, CH
Positions:1994-1996: Post Doc in the Department of Biology at the EMORY University in Atlanta (Georgia, USA)1997-2001: Post Doc in the Department of Cardiology and
Angiology of Hannover Medical School2001-recent: Group Leader in Molekular Cardiology in the
Department of Cardiology and Angiology
Major research interests:Analysis of mechanisms of stress-dependent signal transductionresponsible for the transition of compenatory hypertrophy todecompensated hypertrophy in the heart. Focus on the gp130-JAK/STAT signaling pathway and AP-1 transcription factors.Regulation and role of pro-angiogenic gene CCN1 in the pathophysiology of the heart.
Selected Publications:Hilfiker A., Hilfiker-Kleiner D., Pannuti A., Lucchesi J. C.. EMBO J. 1997; 16: 2054-2060
Hilfiker-Kleiner D, Hilfiker A, Schieffer B, Engel D, Mann DL, Wollert KC, DrexlerH Cardiovasc Res. 2002; 53(2):460-469.
Hilfiker A., Hilfiker-Kleiner D., Fuchs M., Kaminski K., Lichtenberg, A., RothkötterH., Schieffer B., and Drexler H. Circulation. 2002; 106(2):254-260
Podewski E.K., Hilfiker-Kleiner D., Hilfiker A., Morawitz H., Lichtenberg A., Wollert K.C. and Drexler H. Circulation. 2003Hilfiker-Kleiner D, Kaminski K, Kaminska A., Fuchs M., Klein G., Podewski E.,Kiian I., Wollert K.C., Hilfiker A., Drexler H. Circulation accepted for publication
First name:Denise
Last name:Hilfiker-Kleiner
Acad. Title:PhD
Address:OE 6887Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/cardiology
Department and function:Professor, Biochemistry (Physiological Chemistry)
Education:1980 Diploma in Biology, University of Hannover1985 Ph. D., Ludwig-Maximilians-University Munich1993 Habilitation in Immunology, Medical School Hannover
Positions:1985-1987: Postdoctoral fellow at the Weizmann Institute of
Science, Rehovot, Israel1987-2001: Group leader, Institute of Pharmacology, Medical
School Hannover2001-2003: GBF-BraunschweigSince 2003: Professor for Biochemistry of Cellular Signal
Transduction, Institute of Biochemistry/Physiological Chemistry, Medical School Hannover
Major research interests:Post-transcriptional control of gene expression in inflammation
- cis-acting RNA elements- regulatory RNA-binding proteins- signalling pathways affecting post-transcriptional mechanisms
Selected Publications:Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.-Y.A., Shyu A.-B., Müller M., Gaestel M., Resch K., Holtmann. H. EMBO J. 1999; 18:4969-4980.Holtmann H., Winzen R., Holland P., Eickemeier S., Hoffmann E., Wallach D., Malinin N., Cooper J.A., Resch K., Kracht M. Mol. Cell. Biol. 1999; 19:6742-6753.Bollig F., Winzen R., Kracht M., Ghebremedhin B., Ritter B., Wilhelm A., Resch K., Holtmann H. Eur. J. Biochem. 2002; 269:5830-5839.Winzen R., Gowrishankar G., Bollig F., Redich N., Resch K., Holtmann H. Mol. Cell. Biol. 2004, in press.
First name:Helmut
Last name:Holtmann
Acad. Title:Prof. Dr.
Address:OE 4310Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/institute/biochemie
Department and function:Group Leader, Clinical Immunology
Education:1981-1986 Biology in Hannover
Positions:1987-recent Scientist in the Division of Clinical Immunology, MHH1992 PhD in Biology, MHH2003 Habilitation in Immunology, MHH
Major research interests:Analysis of Natural Killer (NK) cell subpopulations. Our particular interest is focused on NK cells with weak cytoxic capacity that are supposed to play an important role in immune regulation.
Selected PublicationsR. Jacobs, G. Hintzen, A. Kemper, K. Beul, G. Behrens, S. Kempf, K. W. Sykora und R. E. Schmidt. Eur J Immunol 2001; 31: 3121-3126.
R. Jacobs, C. R. Pawlak, E. Mikeska, D. Meyer-Olson, M. Martin, C. J. Heijnen, M. Schedlowski und R. E. Schmidt. Rheumatol 2001; 40: 868-875.
J. M. Kittner, R. Jacobs, C. R. Pawlak, C. J. Heijnen, M. Schedlowski und R. E. Schmidt. Rheumatol 2002; 41: 1031-1039.
R. H. Straub, J. M. Kittner, C. J. Heijnen, M. Schedlowski, R. E. Schmidt und R. Jacobs. J Rheumatol 2002; 29: 1659-1664.
R. Jacobs, H. Heiken und R. E. Schmidt. Mol Immunol 2004; in press:
R. Jacobs, K. Weber, K. Wendt, H. Heiken und R. E. Schmidt. J Clin Immunol 2004; in press
First name:Roland
Last name:Jacobs
Acad. Title:PD Dr.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/immun
Department and function: Director, Toxicology
Education:1976-1988 Pharmacy in Münster
Medicine at Free University Berlin
Positions:1989-1995 Postdoc positions in Pharmacology at the Universities
of Giessen, Essen, Homburg/Saar1997 Post Orange Fellowship of INSERM in Nice, France1995-2000 Assistant Professor at the University of Freiburg2000 Professor of Toxicology, MHH
Major research interests:The molecular and cellular mode of action of bacterial protein toxins and the functional consequences on the signal transduction of the target cells.
Selected Publications
Vetter, IR, Hofmann, F, Wohlgemut, S, Herrmann, C, Just, I. J. Mol. Biol. 2000; 301:1091-1095Wilde, C, Chhatwal, GS, Schmalzing, G, Aktories, K, Just, I. J. Biol. Chem 2001;276:9536-9542Wilde, C, Barth, H, Sehr, P, Han, L, Schmidt, M, Just, I, Aktories, K J. Biol. Chem. 2002; 277:14771-14776Gerhard, R, John, H, Aktories, K, Just, I Mol. Pharmacol. 2003; 63:1349-1355Genth H, Gerhard R, Maeda A, Amano M, Kaibuchi K, Aktories K, Just, I. J. Biol: Chem. 2003; 278: 28523-28527Ahnert-Hilger G, Höltje M, Große G, Pickert G, Mucke C, Nixdorf-Bergweiler B, Boquet P, Hofmann F, Just I. J. Neurochem. 2004, in press
First name:Ingo
Last name:Just
Acad. title:Prof. Dr.
Address:OE 5340Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/
institute/toxikologie/
Department and function:Professor, Molecular Biology of Vertebrates
Education:1983-1989 University of Tübingen, Biochemistry1987-1988 Queen Mary College, London, Biochemistry1989-1990 Diploma thesis, MPI Tübingen1990-1993 PhD thesis, MPI Tübingen
Positions:1993-1994 Postdoc, MPI Tübingen1994-1996 Postdoc, Harvard University1997-2001 Group leader, MPI FreiburgSince 2001 C3 Professor, MHH
Major research interests:Genetic control of vertebrate (mouse) development:- Organogenesis (organs of mesodermal origin like kidneys, skeleton,muscles, heart)
- Function of Wnt and Tbx genes in development
Selected Publications:Kispert A, Vainio S, McMahon AP. Development 1998; 125: 4225-4234Herrmann BG, Koschorz B, Wertz K, McLoughlin KJ, Kispert A. Nature 1999; 402: 141-146Leitges M, Neidhardt L, Haenig B, Herrmann BG, Kispert A. Development 2000; 127: 2259-2267Kohlhase J, Heinrich M, Liebers M, Frohlich Archangelo L, Reardon W, Kispert A. Cytogenet Genome Res. 2002; 98(4):274-7Moeller C, Swindell EC, Kispert A, Eichele G. Development. 2003; 130(21):5103-11.
First name:Andreas
Last name:Kispert
Acad. Title:Prof. Dr.
Address:OE 5250Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:http://www.ifm-mhh.de.vu/
Department and function:Professor; Pediatric Hematology/Oncology
Education:1983-1990 Medical School (University Ulm, Munich)1992 Magister Artium, Philosophy2000 Doctorat Immunology (Institut Pasteur, Paris)
Positions:1990 Residency in Pediatrics, University Munich1991-1994 Residency and Research Associate Hôpital Necker
Enfants Malades, Paris1994-1995 Residency in Pediatrics, University Freiburg1995-1998 Clinical and Research Fellow
Children‘s Hospital, Harvard Medical School Boston1998-2000 Instructor in Pediatrics and Research Associate, Howard
Hughes Medical Instit., Harvard Medical School, Boston2000- Hannover Medical School
Major research interests:Gene Therapy, Tumor Immunology, Stem Cell Biology
Selected Publications:Klein C, Bueler H, Mulligan RC. J Exp Med 2000; 191: 1699-1708Dahl AM, Klein C, Andres PG, London CA, Lodge MP, et al.. J Exp Med 2000,191:2031-2038Snapper SB, Takeshima F, Rosen FS, Antón I, Thomas S, et al. Nat Cell Biol 2001;3:897-904Robert C, Klein C, Cheng G, Kogan A, Mulligan RC, et al. Gene Therapy 2003; 10(17):1479-86Klein C, Nguyen D, Liu CH, Mizoguchi E, Bhan AK, Rosen FS, et al. Blood 2003; 101(6):2159-66
First name:Christoph
Last name:Klein
Acad. Title:Prof. Dr., PhD
Address:OE 6780Hannover Medical School
Phone and e-mail:+49-511-532 [email protected]
Further information:www.mh-hannover.de/Kliniken/paed_haemonko/Klinik.htm
Department and function:Assistant Medical Director, Medical Microbiology
Education:1980 - 86 Study of Medicine at the Johannes-Gutenberg University
Mainz1988 - 91 Experimental training in Molecular Biology and Cell
Biology at the Baylor College of Medicine, Department ofCell Biology, Houston, Texas, Medical Center
2000 Consultant with board certification in Med. Microbiol.
Positions:1987 - 88 Research Assistent in the Department of Medical
Microbiology, Johannes-Gutenberg University, Mainz1991 -2000 Research Assistant and, from 2001 on, Assistant Medical
Director at the Department of Medical Microbiology, MHH
Major research interests:Basic research on …1. Chlamydia: Bacteria–host-cell interaction, regulated host-cell genes, mechanisms and signalling pathways2. Complement: Anaphylatoxic peptides C3a, C5a and their G-proteincoupled receptors as part of the innate immunity, receptor regulation on various levels including gene-regulation and interaction with cytokines
Selected Publications:Hess S., et al.. Arthritis Rheum. 2001; 44: 2392-2401Settmacher B., et al. Eur J Immunol. 2003; 33: 920-927Hess S, et al. Cell Microbiol. 2003; 5(11):785-95.
First name:Andreas
Last name:Klos
Acad. Title:Prof. Dr.
Address:OE 5210Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/institute/mikrobiologie/
Department and function:Group Leader, Biochemistry (Physiological Chemistry)
Education: 1978-1985 Medical School, Charkov, Ukraine1987-1991 PhD thesis
Positions:Research Assistent
Major research interests:MAPK cascades activated by stress or cytokinesSignalling events that are triggered by p38 activity,and analyse how these events contribute to specific gene expression and cellular responses.
Selected Publications:Kotlyarov A., Neininger C., Schubert R., Eckert C., Birchmeier H-D, et al. Nature Cell Biol. 1999; 1: 94-97.Kotlyarov A, Gaestel M. Biochem. Soc. Trans. 2002; 30: 959-963.Kotlyarov A, Yannoni Y, Fritz S, Laaß K, Telliez J-B, et al. Mol. Cell. Biol. 2002; 22: 4827–4835.Shi Y, Kotlyarov A, Laabeta K, Gruber AD, Butt E, et al. Mol Cell Biol. 2003; 23(21):7732-41.
First name:Alexey
Last name:Kotlyarov
Acad. Title:MD
Address:OE4310Hannover Medical School
Phone and e-mail:[email protected]
Further information:www.mh-hannover.de/ institute/biochemie/
Department and function:Head of Immunology, Allergology and Clinical Inhalation Research, ITEM
Education:1981-89 Medicine in Hannover, Göttingen and Hartford (USA)1998-2000 Degree in Internal Medicine, Respiratory Medicine,
Allergology and Intensive Care Medicine, Hannover Medical School (MHH)
1999 Habilitation in Internal Medicine (MHH)
Positions:1989-93 and1995-2000: Assistenzarzt Medical School Hannover (MHH)1993-95: Postdoctoral Fellowship University Bochum and
University Southampton (German Research Council Scholarship)
since 2000: Professor of Immunology, Allergology and Clinical Inhalation Research, MHHand Head of Department Immunology, Allergology and Clinical Inhalation Research, Fraunhofer ITEM
Major research interests:Pathophysiology and therapeutic interventions of airway diseases, in particular asthma. Preclinical and clinical research.
Selected Publications:Krug N, Erpenbeck VJ, Balke K, Petschallies J, Tschernig T, et al. Am J Respir Cell Mol Biol 2001;25:125-131.Krug N, Tschernig T, Erpenbeck VJ, Hohlfeld JM, Köhl J. Am J Respir Crit Care Med 2001;164:1841-1843. 29.Erpenbeck VJ, Hohlfeld JM, Volkmann B, Hagenberg A, Geldmacher H, et al. J Allergy Clin Immunol 2003; 111: 1319-27.Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, et al. J Exp Med 2003; 198; 455-67.Erpenbeck VJ, Hagenberg A, Dulkys J, Elsner J, Krentel H, et al. Am J Respir Crit Care Med 2004; 169; 578-586.Hohlfeld JM, Schmiedl A, VJ Erpenbeck, Venge P, Krug N. J Allergy Clin Immunol 2004; 113: 496-502.Weigt H, Muhlradt P, Larbig M, Krug N, Braun A. J Immunol 2004 (in press).
First name:Norbert
Last name:Krug
Acad. Title:Prof. Dr.
Address:Fraunhofer Institute forToxicology and Experimental Medicine Nikolai-Fuchs-Str. 130625 Hannover
Phone and e-mail:++49- 511- 5350 [email protected]
Further information:www.item.fraunhofer.de
Department and function: Group Leader, Rheumatology,Consultant for Internal Medicine and Rheumatology
Education:1984-1991 Study of medicine at Hannover Medical School
Positions:1991-1993 Physician in practive/fellow Hannover Medical School1993-1995 Postdoctoral Fellowship
University of California Los Angeles1993-2000 Fellow in the Department of Internal Medicine at
Hannover Medical School2000 Consultant for Internal Medicine2001 Consultant for Rheumatology
Major research interests:I am interested in the etiopathogenesis, genetics and diagnosis of undifferentiated and reactive arthritis & spondyloarthritis: • analysis of mechanisms of bacterial persistence, • the development of optimized diagnostic tools to discover
intraarticularly persisting bacteria, • identification of genetic susceptibility factors of arthritis.
Selected publications:Kuipers, J.G., Bialowons, A., Dollmann, P., Jendro, M.C., Koehler, et al. Clin. Exp.Rheumatol., 2001, 19:47-52.Seta, N., Granfors, K., Sahly, H., Kuipers, J.G., Song, Y.W., et al. Arthritis Rheum.; 2001; 44:931-939.Putschky, N., Schnarr, S., Wollenhaupt, J., Zeidler, H., Kuipers, J.G. Ann Rheum Dis2001; 60:632-634.Schnarr, S., Putschky, N., Jendro, M.C., Zeidler, H., Hammer, M., Kuipers, J.G.,Wollenhaupt, J. Arthritis Rheum. 2001; 44: 2679-2685. Kuipers, J.G., Andresen, J., Köhler, L. Schnarr, S., Putschky, N., Zeidler, H.,Wollenhaupt, J. Clin Exp Rheumatol. 2002, 20:185-192.Kuipers, J.G., Bialowons, A., Dollmann, P., Jendro, M.C., Wagener, N., Rebmann, V., et al. Clin. Exp. Rheumatol. 2002, 20:455-462Jendro, M.C., Fingerle, F., Deutsch, T., Liese, A., Köhler, L., et al. Med. Microbiol.Immunol 2004 193: 45-52
First name:Jens
Last name:Kuipers
Acad. Title:Priv.-Doz. Dr. med.
Address:OE 6850Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/kliniken/rheumatologie/
Department and function:Professor, Animal Breeding and Genetics, TiHo
Education:1987-1992 Diplom, Chemistry, University of Munich1993-1995 PhD thesis, Biochemistry, U. of Munich
Positions:1996 Postdoc, UTHSC, San Antonio, Tx, USA1996-1999 Postdoc (Habilitation), U. of Göttingen
Major research interests:Molecular genetics and genomics of domestic animals (dog, horse, pig, cattle)Identification of genetic variations that lead to hereditary diseases or other phenotypic traits such as economically important performance traits
Selected Publications:Drögemüller C, Distl O, Leeb T. Genome Res 2001; 11: 1699-1705.Drögemüller C, Peters M, Pohlenz J, Distl O, Leeb T. J Mol Med 2002; 80: 319-323.Martins-Wess F, Voß-Nemitz R, Drögemüller C, Brenig B, Leeb T. Genomics 2002; 80: 416-422.Backofen B, Jacob R, Serth K, Gossler A, Naim HY, Leeb T. Eur J Biochem. 2002; 269(21):5240-5. Martins-Wess F, Milan D, Drogemuller C, Vobeta-Nemitz R, Brenig B, et al. BMC Genomics. 2003; 4(1):20. Sander P, Hamann H, Pfeiffer I, Wemheuer W, Brenig B, et al. Neurogenetics. 2004
First name:Tosso
Last name:Leeb
Acad. Title:Prof. Dr.
Address:Department of AnimalBreeding and GeneticsSchool of VeterinaryMedicine HannoverBünteweg 17p30559 Hannover
Phone and e-mail:++49-511-953 [email protected]
Further information:www.tiho-hannover.de/ einricht/zucht/t_leeb.htm
Department and f unction:Group Leader and Head of the Laboratory of Molecular Diagnostics; Pathology
Education:1986-1992 University of Hannover, Biochemistry1992-1996 PhD, Molecular Biology
Positions:1996-1998 Head Laboratory of Molecular Diagnostics
Institute of Pathology, Bielefeldsince 1999 Research Group Leader and Head of the
Laboratory of Molecular Diagnostics,Institute of Pathology, Hannover Medical School
Major research interests:Epigenetics of malignant neoplasiaTumor evolutionMolecular diagnosis of neoplasiaMain focus on breast cancer and hematological neoplasia in humans
Selected Publications:Lehmann U, Kreipe H. Methods 2001; 25: 409-418.Lehmann U, Celikkaya G, Hasemeier B, Länger F, Kreipe H. Cancer Res 2002;62: 6634-6638.Kleeberger W, Versmold A, Rothamel T, Glockner S, Bredt M, et al. Am J Pathol. 2003; 162(5):1487-94Tessema M, Langer F, Dingemann J, Ganser A, Kreipe H, Lehmann U.Leukemia. 2003; 17(5):910-8. Lehmann U, Brakensiek K, Kreipe H. Ann Hematol. 2003 [Epub ahead print]
First name:Ulrich
Last name:Lehmann
Acad. Title:PD Dr. rer. nat.
Address:OE 5102Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/ institute/pathologie/
Department and functionGroup Leader, Cell Biology
Education:1982-1987 Biology, Technical University of Munich1988-1992 PhD Thesis, MPI for Biochemistry, Martinsried
Positions:1992-1997 Postdoc at Washington University, St. Louis, MO, USA1997-2000 Assistant in the Department of Immunobiology,
University of Bonnsince 2000 Assistant in the Department of Cell Biology
Major research interests:Antigen processing and presentation; intracellular sorting of MHC II molecules, antigens and cofactors for antigen processing; lipid rafts and their function in MHC II biology; roles of intestinal epithelial cells in mucosal immunity
Selected Publications:Lindner R., Unanue E. EMBO J. 1996; 15: 6910-6920.Lindner R. Electrophoresis 2001; 22: 386-393.Lindner R. Traffic 2002; 3: 133-146.
First name:
Robert
Last name:Lindner
Acad. Title:Dr. rer. nat.
Address:OE 4130Hannover Medical School
Phone and e-mail:++49- 511- 532-2918
Further information:www.mh-hannover.de/Institute/Zellbiologie/
Department and function:Group Leader, Gastroenterology, Hepatology and Endocrinologyand Molecular Biology
Education:6/96 MD1/98-12/00 Post Doc Fred Hutchinson Cancer Center, Seattle WA;
USA
Positions:since 1/96 Dept. of Gastroenterology, MHHsince 2/01 Dept.of Gastroenterology and Institute for Molecular
Biology
Major research interests:My scientific interest concentrates on the understanding of the mammalian cell cycle, specifically on the control of cyclin dependent kinases. Our research tries to elucidate the molecular regulation of cyclin kinase inhibitors by proteolytic mechanisnms. We are using biochemistry and mouse models as our main tools.
Selected Publication:Malek NP, Sundberg H, McGrew S, Nakayama K, Kyriakides TR, Roberts J. Nature2001; 413: 323-27.Zender L, Hutker S, Liedtke C, Tillmann HL, Zender S, et al. Proc Natl Acad Sci USA 2003; 100(13):7797-802.
First name:Nisar Peter
Last name:Malek
Acad. Title:Dr.med.
Address:OE5250Hannover Medical School
Phone and e-mail:[email protected]
Further information:http://www.mh-hannover.de/ kliniken/gastro/gastro.htm
Department and function:Head, Biotechnology; FAL
Education:1973-1978 Veterinary Sciences, Veterinary University Hannover1978-1980 PhD thesis1985/86 Texas A&M University, College of Veterinary
Medicine1989: Habilitation Veterinary University Hannover1994: Apl. Professor for Reproductive Biology Veterinary
University Hannover
Positions:1980-1987: Scientist at the Institute for Animal Science1987-now: Head of Dept. Biotechnology at the Institute
Major research interests:Molecular regulation of preimplantation developmentTransgenesis in domestic species, Use of agricultural animals for biomedical applications, Aspects of somatic cloningGenetic diversity
Selected Publications:Niemann H, Wrenzycki C. Theriogenology 2000, 53: 21-34.Fernandez B, Buehler A, Wolfram S, Espanion G, Franz WM, et al. Circulation Research 2000, 87: 207-213.Kirchhof N, Carnwath JW, Lemme E, Anastassiadis K, Schöler H, Niemann H. Biol. Reprod.2000, 63: 1708-1715.Niemann H, Verhoeyen E, Wonigeit K, Lorenz R, Hecker J, et al. Transplantation 2001. 72: 1896-1906.Brambrink, Wabnitz P, Halter R, Klocke R., Carnwath J, et al. Biotechniques 2002, 33: 376-385.Kues WA, Carnwath JW, Paul D, Niemann H. Cloning Stem Cells. 2002; 4:231-43. Wrenzycki C, Herrmann D, Niemann H. Biol Reprod. 2003; 68(6):2073-80. Anger M, Kues WA, Klima J, Mielenz M, Kubelka M, et al. Mol Reprod Dev. 2003; 65(3):245-53. Terletski V, Schwarz S, Carnwath J, Niemann H. Microbiol Res. 2003; 158(2):135-42.
First name:Heiner
Last name:Niemann
Acad. Title:Prof. Dr. med.vet. Dr.habil.
Address:Dept. BiotechnologyInstitute for Animal Science, MarienseeFAL, Hoeltystr. 1031535 Neustadt
Phone and e-mail:++49-(0)[email protected]
Further information:www.tzv.fal.de
Department and function:Professor, Cardiology and Angiology
Education:1984-1990 Medical School, Albert Ludwigs
University Freiburg i. Br.1987-1990 Doctoral thesis: Role of the Renin-
Angiotensin System in Experimental Heart Failure.1992-1993 Clinical Residency, Dept. of Cardiology,
Freiburg, University Hospital1993-1996 Postdoc, Dept. Of Experimental
Pathology, EMORY University Atlanta, USA.1996- Dept. Of Cardiology and Angiology, MHH
Positions:1992-1993 Clincial Residency1993-1996 Post-doc1996-1999 Clinical Residency1999-2001 Research Associatesince 2001 Assistant Prof. of Medicine
Major research interests:Vascular biology and Signal transduction of G-Protein coupled receptors. Experimental and clinical atherosclerosis research
Selected Publications:Schieffer B., Luchtefeld M., Hilfiker A., Drexler H. Circ Res. 2000, 87:1195-1201.Krämer C, Sunkomat J, Luchtefeld M., Walden M., Forssmann WG., et al. Circ Res. 2002; 90(7):770-6.Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, et al. Circ Res. 2003; 92(11): e80-6 Luchtefeld M, Drexler H, Schieffer B. Biochem Biophys Res Commun. 2003; 308(3):668-72.
First name:Bernhard
Last name:Schieffer
Acad. Title:PD Dr. med.
Address:OE 6880Hannover Medical School
Phone and e-mail:++49-511-532 4666++49-511-532 [email protected]
Further information:www.mh-hannover.de/ kliniken/kardiologie/htm/ home.html
Department and function:Director, Cell and Molecular Pathology
Education:1975-1982 Studied medicine at the Ludwig Maximilian University
in Munich and the Christian Albrecht University of Kiel
Positions:1983-2000 Assistant, University Lecturer, then Professor at the
Institute of Human Genetics, University of Kiel1987-2000 Deputy Director of the Institute of Human Genetics,
University of Kiel2001-2003 Director of the Institute of Cell and Molecular
Pathology, Hannover Medical School
Major research interests:My main interests are tumor genetics, with particular emphasis on the dissection of tumorigenesis, development of new diagnostic tools, and on genetic counseling in hereditary cancer syndromes.
Selected Publications:Zhang Q, Siebert R, Yan M, Hinzmann B, Cui X, et al. Nature Genetics 1999; 22: 63-68Schlegelberger B, Zwingers T, Harder L, Nowotny H, Siebert R, Vesely M, et al. Blood 1999; 94: 3114-3120Zhang Y, Matthiesen P, Harder S, Siebert R, Castoldi G, et al. Genes Chromosomes Cancer 2000; 27:52-58Metzke-Heidemann S, Harder L, Gesk S, Schoch R, Jenisch S, et al. GenesChromosomes Cancer 2001; 31: 10-14 McPherson JD, Marra M, Hillier L, Rosenthal A, Wen G, et al. Nature 2001; 409: 934-41 Steinemann D, Gesk S, Zhang Y, Harder L, Pilarsky C, et al. Genes Chromosomes Cancer. 2003; 37(4):421-6Wilkens L, Flemming P, Gebel M, Bleck J, Terkamp C, et al. Proc Natl Acad Sci USA. 2004;101(5):1309-14.
First name:Brigitte
Last name:Schlegelberger
Acad. Title:Prof. Dr..
Address:OE 5120Hannover Medical School
Phone and e-mail:++49-0511-532 [email protected]
Further information:www.mh-hannover.de/institute/zellpathologie/
Department and function:Director, Clinical ImmunologyChairman of the MD/PhD Program
Education:1976 M.D., Medical School of the Rheinische Friedrich-
Wilhelms-Universität Bonn1977 Masters of Psychology, Rheinische Friedrich-Wilhelms-
Universität Bonn
Positions:1978-83 Instructor in Medicine, Medical School of the University
of Bonn1986-94 Associate Professor of Medicine and Immunology,
Hannover Medical School1995- Head, Professor of Medicine and Immunology, Dept.
Clinical Immunology, Hannover Medical School
Major research interests:Fc receptors, regulation and activation, role in pathogenesis of diseases; activation mechanisms of human natural killer cells; pathogenesis of vasculitis and chronic rheumatoid arthritis; immunotherapy (cytokines and immunoglobulins); immunodeficiencies, AIDS - pathogenesis and treatment; clinical therapy studies
Selected Publications:Hundt M, et al. Eur J Immunol 2001; 31:3475-83.Tillmann HL, et al. N Engl J Med 2001; 345: 715-24Behrens GMN, et al. J Clin Invest 2002; 110: 1319-27.Shushakova N, et al. J Clin Invest 2002; 110: 1823-30.Behrens GM, et al. Eur J Med Res. 2003;8(5):221-5.Werwitzke S, et al. Clin Exp Immunol. 2003;133(3):334-43. Drescher B, et al. Immunology. 2003;110(3):335-40Ulbricht KU, et al. Arthritis Rheum. 2003; 48(12):3542-3.
First name:Reinhold Ernst
Last name:Schmidt
Acad. Title:Prof. Dr. med.
Address:OE 6830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/immunwww-mh-hannover.de/studium/phd
Department and function:Director, Human Genetics
Education:1966-1973 Universities of Freiburg and Basel, Medicine
Positions: 1988-1990 Professor of Human Genetics, Berlin1990- Professor of Human Genetics, Director and Chair, MHH
Major research interests:Molecular Basis of Inherited Disease, Genetics of Behavior in Subhuman Primates, Structure and Ethics of Genetic Service Provision
Selected Publications:Krawczak and Schmidtke: DNA-Fingerprinting, Bios, Oxford (1998)Trefilov, Berard, Krawczak and Schmidtke, Behavior Genet. 2000; 30: 295.Rommel, Karck, Haverich, Schmidtke, Arslan-Kirchner, Hum. Mutat 2002; 20: 406Schmidtke, Nippert, Wolff, Int. Encycl. Soc. Behav. Sci, 6092 (2001)Schubert S, Skawran B, Dechend F, Nayernia K, Meinhardt A, et al. Biol Reprod. 2003; 69(3):968-75.
First name:Jörg
Last name:Schmidtke
Acad. Title:Prof. Dr.
Address: OE 6300Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.human-genetik.net
Department and function:Director, Virology
Education:1980 MD Mainz1986 Habilitation Innsbruck
Positions:1996 MRCPath, London, 2003 FRCPath, London,
Major research interests:Kaposi‘s sarcoma – associated herpesvirus/human herpesvirus 8
Selected Publications:Glenn M, Rainbow L, Aurade F, Davsion A, Schulz TF. J.Virol. 1999; 73: 6953 –6963;Platt GM, Simpson GR, Mittnacht S, Schulz TF. J. Virol. 1999; 73: 9789 – 9795.Greensill J, Sheldon J, Renwick NM, Beer B, Norley S, et al. J. Virol. 2000; 74:1572-1577.Luppi M, Barozzi P, Schulz TF, et al. N Engl J Med 2000; 343: 1378-1385Viejo-Borbolla A, Kati E, Sheldon J, Nathan K, Mattsson K, et al. J.Virol. 2003; 77(12):7093-100.Brinkmann MM, Glenn M, Rainbow L, Kieser A, Henke-Gendo C, Schulz TF. J Virol. 2003; 77(17):9346-58.
First name:Thomas F.
Last name:Schulz
Acad. Title:Prof. Dr. med., FRCPath
Address:OE 5230Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Department and function:Group Leader, Transplant Laboratory
Education:1983 Degree of „Diplom-Biologe“ (Masters Degree in
Biology), University of Braunschweig
1987 Degree of „Dr.rer.nat.“ (PhD), University of Hannover
1994 Habilitation; Venia legendi for Immunology, Hannover Medical School (MHH)
Positions:1983-1987 Research Assistant, MHH
1987-1990 Research Associate, MHH
1990-1991 Fellowship of the German Research Council (DFG), National Jewish Center for Immunology, Denver
1991- Group leader, Transplant Laboratory, MHH
1999- Professor of Immunology
Major research interests:Transplant Immunology/Xenotransplantation: Analysis of human anti-pig T cell responses, development of immunomodulatory antibodies, immunological monitoring of transplant recipients.Analysis of T cell activation in the human: Signal transduction, role ofcell surface molecules (CD28, CD45), CD45 polymorphisms.
Selected Publications:Siefken R, Klein-Heßling S, Serfling E, Kurrle R, Schwinzer R. J Immunol 1998; 161:1645-1651 Jacobsen M, Schweer D, Ziegler A, et al. Nature Gen 2000; 26:495-499Niemann H, Verhoeyen E, Wonigeit K et al. Transplantation 2001; 72:1898-906 Dulat H, von Grumbkow C, Baars W, Schröder N, Wonigeit K, Schwinzer R. Eur J Immunol 2001; 31: 2217-2226Schwinzer R, Witte T, Hundrieser J, et al. Genes Immun 2003; 4:168-169
First name:Reinhard
Last name:Schwinzer
Acad. Title:Prof. Dr.rer.nat.
Address:OE 6220Hannover Medical School
Phone and e-mail:++49- 511- 532 [email protected]
Further information:www.mh-hannover.de/kliniken/visceralchirurgie/
Department and function:Assistant Professor, Virology
Education:1982 – 1988 University of Bonn, Biology1988 – 1989 Columbia University, New York, NY, USA
Immunology1989 - 1993 European Molecular Biology Laboratory, Heidelberg,
Cell Biology
Positions:1993 - 1997 Postdoc and Staff Scientist, Yale University,
New Haven, CT, USA, Dept. Cell Biology1997 – 2002 Group leader, Biochemistry Dept., MHH
Major research interests:Our group is interested in the cell biology of complex DNA viruses. How does a virus get access to a cell, disassemble to uncover its genome for replication, and how is – within a couple of hours – the viral program switched to virus assembly and egress? We have developed several in vivo and in vitro motility assays to analyse the cell biology of Herpes Simplex Virus and particularly the microtubule-mediated capsid transport by digital video microscopy. Using these assays, we characterize cytosolic host factors as well as structural viral proteins important in HSV1 entry and egress.
Selected Publications:Sodeik, Doms, Ericsson, Hiller, Machamer, van' t Hof, et al. J of Cell Biology 1993;121:521-541.Sodeik, Ebersold, Helenius. J of Cell Biology 1997; 136:1007-1021.Ojala, Sodeik, Ebersold, Kutay, Helenius. Mol & Cell Biology 2000; 20:4922-4931.Döhner, Wolfstein, Prank, Echeverri, Dujardin, Vallee, & Sodeik. Molecular Biology Cell 2002; 13:2795-2809.Mabit H, Nakano MY, Prank U, Saam B, Dohner K, et al. J Virol. 2002; 76(19):9962-71
First name:Beate
Last name:Sodeik
Acad. Title:HD Dr. rer.nat.
Address:OE 5320Hannover Medical School
Phone and e-mail:[email protected]
Further information:www.mh-hannover.de/institute/virologie/
Department and function:Group Leader, Pediatric Nephrology and Metabolic Diseases,Consultant for Transplant and Nephrology Ward, Dialysis and Outpatient Service
Education:1975-1983 Medical Schools at Bochum, Stanford and Hamburg1983-85 Clinical Anesthesia
Positions:1985-1986 Pediatrics and Transplant Medicine Heidelberg 1986-1993 Pediatrics, Intensive Care and Pediatric Nephrology,
UKE Hamburg1993-1996 Research Fellow and Deputy Chief of Lab. Div. Of
Immunology, TB Strom Beth Israel Deaconess MedicalCenter, Harvard Medical School, Boston
1996-1997 Clinical Consultant Pediatric Nephrology Charite Berlin1998-now MHH
Major research interests:Transplant Immunology, Activation and Silencing of T-Cells, Quantitative Measurement of T-Cell ResponsesT-Cell Effectors, T-cell driven Primary Renal Diseases
Selected Publications:Strehlau J, Pavlakis M, et al. Proc Natl Acad Sci U S A. 1997;94(2):695-700. Strehlau J, Schachter AD, et. Al. Kidney Int. 2002;61(1):90-5.Pape L, Froede K, Strehlau J, Ehrich JH, Offner G. Pediatr Transplant. 2003; 7(4):302-4Melk A, Henne T, Kollmar T, Strehlau J, Latta K, et al. Kidney Int. 2003; 64(1):314-20.
First name:Juergen
Last name:Strehlau
Acad. Title:Prof. Dr. med.
Address:OE 6720Hannover Medical School
Phone and e-mail:0511-532-5597/[email protected]
Department and function:Professor, Human Genetics
Education:1980 – 1986 Free University Berlin, Medicine1988 MD1995 Specialist in Human Genetics2002 apl. Professorship
Positions:1987 Guestdoc, Cerrahpasha Medical Faculty,
Istanbul, Turky1988 – 1990 Postdoc, Inst. Humangenetics, FU BerlinSince 1991 Head of Molecular Diagnostics, Inst. Human
Genetics, Medical School Hannover
Major research interests:Molecular genetics of several monogenenic disorders like cysticfibrosis, haemochromatosis, morbus Osler, ataxia telangiectasia; neuro-and psychiatro-genetics, genetic screening
Selected Publications:M.Stuhrmann,T.Dörk. Andrologia 2000; 32; 71-83O.Schöffski, J.Schmidtke, M.Stuhrmann. Community Genetics 2000; 3:2-11M.Stuhrmann, N.Graf, T.Dörk, J.Schmidtke. Journal of Pediatrics (Suppl III) 2000;159:S186-S191M.Stuhrmann, L.Bashawri, MA.Ahmed, et al. British Journal of Haematology2001, 112: 616-620J.Ockenga, T.Dörk, M.Stuhrmann. Journal of Medical Genetics 2001; 38:243-244D.Heller, U.Schneider, J.Seifert, KF.Cimander, M.Stuhrmann. Addiction Biology2001, 6:183-187M.Schürmann, M.Albrecht, E.Schwinger, M.Stuhrmann. Eur J Hum Genet 2002;10:729-732Groman JD, Hefferon TW, Casals T, Bassas L, Estivill X, et al. Am J Hum Genet. 2004; 74(1):176-9.
First name:Manfred
Last name:Stuhrmann-Spangenberg
Acad. Title:Prof. Dr. med.
Address:OE 6300Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/kliniken/humangenetik
Department and function:Professor; Gastroenterology, Hepatology and Endocrinology
Education:1979 Abitur, Max-Planck-Gymnasium,
Nürtingen/Baden-Württemberg1979-81 Apprenticeship, Dresdner Bank AG, Stuttgart1981-87 Study of Medicine, University of Mainz and
Tübingen1987 M.D., University o Mainz 1988 FMGMES
Positions:1988-91 Internal Medicine, University of Mainz1991-93 Dep. of Pharmacology, UCSD, USA1993-96 Dep. of Gastroenterology & Hepatology1996- Associate Professor Dep. of Gastroenterology,
Hepatology & Endocrinology
Major research interests:Mechanisms of viral and immune mediated liver failure and liver regeneration in humans and animal models
Selected Publications:Ludde T, Kubicka S, Plumpe J, Liedtke C, Manns MP, et al. Oncogene. 2001; 20: 5264-78.Jaeckel E, Cornberg M, Wedemeyer H, Santantonio T, Mayer J, et al.. N Engl J Med. 2001; 345: 1452-7.Bock CT, Tillmann HL, Torresi J, Klempnauer J, Locarnini S, et al. Gastroenterology. 2002; 122: 264-73.Wuestefeld T, Klein C, Streetz KL, Betz U, Lauber J, et al. J Biol Chem. 2003; 278: 11281-8. Tacke F, Brabant G, Kruck E, Horn R, Schoffski P, et al. J Hepatol. 2003; 38(4):447-54Luedde T, Rodriguez ME, Tacke F, Xiong Y, Brenner DA, Trautwein C.Hepatology. 2003; 37(4):833-41.Liedtke C, Groger N, Manns MP, Trautwein C. J Biol Chem. 2003; 278(30):27593-604.Bock CT, Buerke B, Tillmann HL, Tacke F, Kliem V,et al. Gastroenterology. 2003; 124(7):1809-20. Klein C, Wustefeld T, Heinrich PC, Streetz KL, Manns MP, Trautwein C.Eur J Immunol. 2003; 33(8):2251-61
First name:Christian
Last name:Trautwein
Acad. Title:Prof. Dr. med.
Address:OE 6810Hannover Medical School
Phone and e-mail:xx49/511/[email protected]
Further information:http://www.mh-hannover.de/kliniken/gastro/gastro.htm
Department and function:Head, ‘Clinical Reasearch Group Pseudomonas‘
Education and positions:1971 - 1976 study of biochemistry1974 - 1981 study of medicine1979 Dr. rer.nat.1984 Dr. med.1991 habilitation1992 professorship
Major research interests:• Genomics• Molecular pathology of cystic fibrosis• Pseudomonas genomics
Selected Publications:Bronsveld I, Mekus F, Bijman J, Ballmann M, de Jonge HR, et al. J Clin Invest. 2001;108:1705-15.Wiehlmann L, Salunkhe P, Larbig K, Ritzka M, Tümmler B. Genome Letters 2002, 1: 123-130Larbig KD, Christmann A, Johann A, Klockgether J, et al. J Bacteriol. 2002; 184:6665-80.Weinel C, Nelson KE, Tümmler B. Environmental Microbiology 2002, 4: 809-818Kiewitz C, Tümmler B. Genome Letters 2002, 1: 111-114 Mekus F, Laabs U, Veeze H, Tümmler B. Hum Genet. 2003;112:1-11.
Klockgether J, Reva O, Larbig K, Tummler B. J Bacteriol. 2004; 186(2):518-34.
First name:Burkhard
Last name:Tümmler
Acad. Title:Prof. Dr. Dr.
Address:OE 6710Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www. mh-hannover.de/ kliniken/kinderheilkunde/kfg/index.htm
Department and function: Director, Cell Biology
Education:1974: Diploma in Biology from the Free University Berlin1976: PhD obtained from the Free University Berlin1977-79: EMBO Fellow at the MRC Unit for Biophysics at
King‘s College in London, UK1979-82: Postdoctoral fellow (DFG) at the Biological
Laboratories at Harvard University (Cambridge, Ma)1982-84: Heisenberg-Fellow at the LMB in Cambridge (UK)
and the Max-Planck Institute for BiophysicalChemistry in Göttingen, Germany.
Positions:1986-92: Junior-Research group leader at the Max-Planck-
Institute for Biochemistry, Martinsried, Germany1992-1998: Associate Professor at the Dept. of pathology at
Washington University St. Louis, MOsince 1998: Professor for Cell Biology at MHH
Major research interests:Intracellular vesicular transport, functions of molecular chaperones
Selected Publications:Ungewickell, E., H. Ungewickell, et al. Nature 1995; 378: 632-635.Umeda, A., A. Meyerholz, et al. Eur J Cell Biol 2000; 79(5): 336-342.Scheele, U., C. Kalthoff, et al. J Biol Chem 2001; 276(39): 36131-36138.Kalthoff, C., S. Groos, et al. Mol Biol Cell 2002; 13(11): 4060-4073.Kalthoff, C., J. Alves, et al. J Biol Chem 2002; 277(10): 8209-8216.Scheele, U., J. Alves, et al. J Biol Chem. 2003; 278(28):25357-68.Hinrichsen, L., J. Harborth, et al. J Biol Chem. 2003; 278(46): 45160-70.
First name:Ernst
Last name:Ungewickell
Acad. Title:Prof. Dr. rer. nat.
Address:OE 4130Hannover Medical School
Phone and e-mail: ++49-511- 532 [email protected]
Further information:www.mh-hannover.de/institute/zellbiologie/
Department and function:Head, Central Institute for Biophysical and BiochemicalProcedures
Education:1968-1972 Chemistry, Technical University Braunschweig1972 – 1976 Dissertation, University Hannover
Positions:1973- Hannover Medical School
Major research interests:Protein nucleic acid and protein protein interactions Single stranded DNA binding proteins, analytical ultracentrifugation, biophysical chemistry in solution
Selected Publications:Urbanke C, Wray J. Biochem J 2001; 358:165-73 Grazulis S, Deibert M, Rimseliene R, Skirgaila R, Sasnauskas G, et al. Nucleic Acids Res 2002; 30(4):876-85Meyer S, Urbanke C, Wahle E.. Biochemistry 2002 ;41(19):6082-9Landwehr M, Curth U, Urbanke C. Biol Chem 2002; 383(9):1325-33 Schubert WD, Urbanke C, Ziehm T, Beier V, Machner MP,et al. Cell 2002; 111(6):825-36Witte G, Urbanke C, Curth U. Nucleic Acids Res. 2003; 31(15):4434-40Zaremba M, Urbanke C, Halford SE, Siksnys V J Mol Biol. 2004; 336(1):81-92
First name:Claus
Last name:Urbanke
Acad. Title:Prof. Dr.
Address:OE 8830Hannover Medical School
Phone and e-mail:++49-511-532 [email protected]
Further information:http://www.mh-hannover.de/einrichtungen/bpc/
Department and function: Head, Molecular Immunology, GBF
Education:1969-1978 Biology at the Free University of Berlin,
Special Studies: Molecular Biology and Genetics1974-1978 PhD Student at the Basel Institute for Immunology,
Basel, Switzerland
Positions:1978-1980 Research Associate at the Salk Institute for Biological
Studies, Department of Developmental Biology, San Diego,USA.
1980-1983: Scientific Assistant at the Friedrich-Miescher-Laboratorium of the Max-Planck-Gesellschaft, Tübingen, Germany.
1983-1989: Member at the Basel Institute for Immunology, Basel, Switzerland.
1989-1990: Visiting Professor at the Institute for Immunology and Rheumatology, University of Oslo, Oslo, Norway.
1990-present: Group leader at the GBF (Gesellschaft für Biotechnologische Forschung), Braunschweig, Germany.
Major research interests:Interaction of bacteria with the immune system.B cell development.
Selected PublicationsDarji A, Guzmán CA, Gerstel B, Wachholz P, Timmis KN, Wehland J, ChakrabortyT, Weiss S. Cell 1997; 91: 765-775.Engel H, Bogen B, Müller U, Andersson J, Rolink A, Weiss S. Eur. J. Immunol. 1998; 28: 2289-2299.Hense M, Domann E, S. Krusch S, Wachholz P, Dittmar KEJ, Rohde M, Wehland J, Chakraborty T, Weiss S. Cell. Microbiol. 2001; 3: 599-609 .Krusch S, E. Domann E, M. Frings M, A. Zelmer A, M. Diener M, T. Chakraborty T, S. Weiss S. J. Gene Med. 2002; 4, 655-667.Kretschmer K, Joungebloud A, Stopkowicz J, Stoermann B, Hoffmann R, Weiss S.J. Immunol. 2003; 171, 1192-201.
First name:Siegfried
Last name:Weiss
Acad. Title:Dr. rer.nat.
Address:AG MolekulareImmunologie,Mascheroder Weg 1a,38124 Braunschweig
Phone and e-mail:++49-0531-6181-230, [email protected]
Further information:[email protected]>-> Forschung Molecular Immunology
Department and function:Director, Pediatric Hematology/Oncology
Education:1969-1973 University Tübingen, Medicine1973-1975 Freie Universität Berlin1975 Dr. med.1976 Approbation1984 Board certified Pediatrician
Positions:1985-1987 Assist. Professor, Head Laboratory of
Cytokine Biology, Memorial Sloan KetteringCenter, New York
1987-1993 Professor for Pediatrics, MHH1993-1997 Professor for Specific Pediatric Hematology
and Oncology, MHHSince 1997 Head, Dept. of Pediatric Hematology/
Oncology, MHH
Major research interests:Cytokines, Hematopoietic stem cells, Bone marrow failure syndromes, Leukemias
Selected Publications:Welte K, Gabrilove J et al. Blood 1996 88 (6): 1907-1929.Ballmaier M, Germeshausen M et al. Blood 2001; 97 (1) 139-146.Tschan CA, Pilz C, Zeidler C, Welte K et al. Blood 2001; 97(6):1882-1884.Germeshausen M, Ballmaier M,Welte K. Ann NY Acad Sci 2001; 938:305-320.Germeshausen M, Schulze M, Ballmaier et al. Br J Hematol. 2001; 115:222-224.Zeidler C, Welte K. Semin Hematol 2002; 39(2):82-88.Dale DC, Cottle TE, Fier CJ, Bolyard AA et al. Am J Hematol. 2003; 72(2):82-93.Beger C, Gerdes K, Lauten M, Tissing WJ, Fernandez-Munoz I, et al. Br J Haematol. 2003;122(2):245-52.
First name:Karl
Last name:Welte
Acad. Title:Prof. Dr. med.
Address:OE 6780Hannover MedicalSchool
Phone and e-mail:++49-511-532 [email protected]
Further information:www.mh-hannover.de/Kliniken
Department and function:Professor, Dermatology
Education:Medical Doctor, Professor of Medicine
Positions:1985-1989 Post Doc in the Dept´s of Immunology in Hannover and in Goettingen1989-1994 Clinicail Education in the the Field of Dermatology in Hannoversince 1994: Registrar („Oberarzt“) in the Dept of Dermatology
Major research interests:Dermatoimmunology:Specifity and functions of skin infiltrating T-cells in eczemaRegulation of cytokine pattern in human T-cells and antigen-presenting cellsExpression and function of anaphylatoxin receptors
Selected Publications:Werfel T, Kirchhoff K, Wittmann M, Begemann G, Kapp A, Heidenreich F, Götze O, Zwirner J. J Immunol 2000; 165:6599-6605Schmid-Ott G, Jaeger B, Meyer S, Stephan E, Kapp A, Werfel T. J Allergy Clin Immunol 2001; 108:455-462Gutzmer R, Langer K, Lisewski MS, Mommert S, Kapp A, Werfel T. J Allergy Clin Immunol 2002; 109:524-531Wittmann M, Kienlin P, Mommert S, Kapp A, Werfel T. J Immunol 2002; 168:3793-3800Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71. Weinmann O, Gutzmer R, Zwirner J, Wittmann M, Langer K, et al. Immunology 2003; 110(4):458-65.
First name:Werfel
Last name:Thomas
Acad. Title:Prof Dr. med.
Address:Dept DermatologyHannover Medical SchoolRicklinger Str. 530449 Hannover
Phone and e-mail:[email protected] [email protected]
Further information:http://www.klinikum-hannover.de/hkl/
Department and function:Juniorprofessor, Dermatology
Education:1989 Abitur, Gymnasium am Geroweiher,
Mönchengladbach1989-96 University Studies, Human Medicine, Heinrich-Heine
University, Düsseldorf
Positions:1996 – 2003 Residency, Department of Dermatology, Hannover
Medical School1999-2001 Postdoctoral Research (DFG Grant)12/2002 - Juniorprofessorin, Department of Dermatology,
Hannover Medical School
Major research interests:Inflammation in eczematous skin diseases, regulation of IL-12, Th1 / Th2 „specific“ transcription factors, heat shock proteins in inflammatory skin diseases (HSP70, HSP27, gp96)
Selected Publications:Wittmann et al. Blood 1999; 94:1717Wittmann et al. Int Arch Allergy Immunol 2001; 124:346Wittmann et al. J Immunol 2002; 168:3793Gutzmer R, Langer K, Mommert S, Wittmann M, Kapp A, Werfel T. J Immunol. 2003; 171(12):6363-71.
First name:Miriam
Last name:Wittmann
Acad. Title:Prof. Dr. med.
Address:Ricklinger Str. 530449 Hannover
Phone and e-mail:0511 9246 278miriamwittmann@ web.de
Further information:http://www.klinikum-hannover.de/hkl/
Department and function:Head, "In Vitro Differentiation" Group, IPK Gatersleben
Education:1964-1969 Study of biology at the Univ. of Greifswald1970-1974 PhD thesis at the Institute of Genetics Gatersleben /
University of Halle1997 Habilitation and venia legendi ("Cell Biology") at the
Medical Faculty, University of Halle
Positions:1974-1991 Scientific co-worker (Mutagenesis and embryonic
stem cell research) Institute of Genetics, Gatersleben,
Academy of SciencesSince 1992 Head of the Research Group "In Vitro Differentiation",
IPK Gatersleben
Major research interests:-Stem cell research: Embryonic and adult (intestinal, hematopoietic) stem cells-Stem cell differentiation into cardiac, skeletal, vascular smooth muscle, neuronal and pancreatic cells-Analysis of cell-cell and cell-matrix interactions-Embryotoxicity analysis in vitro using embryonic stem cells
Selected Publications:Rolletschek A, Chang H, Guan K, Czyz J, Meyer M, Wobus AM. Mech. Dev.2001; 105:93-104.Boheler KR, Czyz J, Tweedie D, Yang H-T, Anisimov SV, Wobus AM. Circ.Res. 2002; 91:189-201.Blyszczuk P, Czyz J, Kania G, Wagner M, Roll U, St-Onge L, Wobus AM.Proc. Natl. Acad. Sci. USA 2003; 100:998-1003Czyz J, Nikolova T, Schuderer J, Kuster N, Wobus AM. Mutat Res. 2004; 557:63-74. Kania G, Blyszczuk P, Czyz J, Navarrete-Santos A, Wobus AM. Methods Enzymol. 2003;365:287-303. Czyz J, Wiese C, Rolletschek A, Blyszczuk P, Cross M, Wobus AM. Biol Chem. 2003; 384(10-11):1391-409.
First name:Anna M.
Last name:Wobus
Acad. Title:PD Dr. rer. nat.
Address:Institute of Plant Genetics (IPK Gatersleben)Corrensstr. 306466 Gatersleben
Phone and e-mail:[email protected]
Further information:www.ipk-gatersleben.de